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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:ZEB1-TAOK3 (FusionGDB2 ID:100176)

Fusion Gene Summary for ZEB1-TAOK3

check button Fusion gene summary
Fusion gene informationFusion gene name: ZEB1-TAOK3
Fusion gene ID: 100176
HgeneTgene
Gene symbol

ZEB1

TAOK3

Gene ID

6935

51347

Gene namezinc finger E-box binding homeobox 1TAO kinase 3
SynonymsAREB6|BZP|DELTAEF1|FECD6|NIL2A|PPCD3|TCF8|ZFHEP|ZFHX1ADPK|JIK|MAP3K18|hKFC-A
Cytomap

10p11.22

12q24.23

Type of geneprotein-codingprotein-coding
Descriptionzinc finger E-box-binding homeobox 1delta-crystallin enhancer binding factor 1negative regulator of IL2posterior polymorphous corneal dystrophy 3transcription factor 8 (represses interleukin 2 expression)zinc finger homeodomain enhancer-binding proteserine/threonine-protein kinase TAO3CTCL-associated antigen HD-CL-09JNK/SAPK-inhibitory kinaseSTE20-like kinasecutaneous T-cell lymphoma-associated antigen HD-CL-09dendritic cell-derived protein kinasejun kinase-inhibitory kinasekinase from chicken
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000320985, ENST00000361642, 
ENST00000559858, ENST00000560721, 
ENST00000542815, ENST00000446923, 
ENST00000419821, ENST00000392533, 
ENST00000537952, ENST00000543709, 
ENST00000536979, 
Fusion gene scores* DoF score11 X 5 X 8=44013 X 15 X 5=975
# samples 1316
** MAII scorelog2(13/440*10)=-1.7589919004962
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/975*10)=-2.60733031374961
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZEB1 [Title/Abstract] AND TAOK3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZEB1(31608221)-TAOK3(118651915), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneZEB1

GO:0000122

negative regulation of transcription by RNA polymerase II

23765923|23814079

HgeneZEB1

GO:0045892

negative regulation of transcription, DNA-templated

20418909

TgeneTAOK3

GO:0006468

protein phosphorylation

10559204

TgeneTAOK3

GO:0006974

cellular response to DNA damage stimulus

17396146

TgeneTAOK3

GO:0046329

negative regulation of JNK cascade

10559204

TgeneTAOK3

GO:0046777

protein autophosphorylation

10559204


check buttonFusion gene breakpoints across ZEB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across TAOK3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-A4MJZEB1chr10

31608221

+TAOK3chr12

118651915

-


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Fusion Gene ORF analysis for ZEB1-TAOK3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000320985ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000320985ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000320985ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000320985ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000320985ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000361642ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000361642ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000361642ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000361642ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000361642ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-
3UTR-3CDSENST00000559858ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
3UTR-3CDSENST00000559858ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
3UTR-intronENST00000559858ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
3UTR-intronENST00000559858ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-
3UTR-intronENST00000559858ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000560721ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000560721ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000560721ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000560721ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000560721ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000542815ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000542815ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000542815ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000542815ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000542815ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-
intron-3CDSENST00000446923ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
intron-3CDSENST00000446923ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
intron-intronENST00000446923ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
intron-intronENST00000446923ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-
intron-intronENST00000446923ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000320985ZEB1chr1031608221+ENST00000419821TAOK3chr12118651915-34181681102221703
ENST00000320985ZEB1chr1031608221+ENST00000392533TAOK3chr12118651915-34181681102221703
ENST00000361642ZEB1chr1031608221+ENST00000419821TAOK3chr12118651915-3371121632174703
ENST00000361642ZEB1chr1031608221+ENST00000392533TAOK3chr12118651915-3371121632174703
ENST00000560721ZEB1chr1031608221+ENST00000419821TAOK3chr12118651915-333181232134703
ENST00000560721ZEB1chr1031608221+ENST00000392533TAOK3chr12118651915-333181232134703
ENST00000542815ZEB1chr1031608221+ENST00000419821TAOK3chr12118651915-332171132124703
ENST00000542815ZEB1chr1031608221+ENST00000392533TAOK3chr12118651915-332171132124703

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000320985ENST00000419821ZEB1chr1031608221+TAOK3chr12118651915-0.0076965460.9923035
ENST00000320985ENST00000392533ZEB1chr1031608221+TAOK3chr12118651915-0.0076965460.9923035
ENST00000361642ENST00000419821ZEB1chr1031608221+TAOK3chr12118651915-0.0083059730.99169403
ENST00000361642ENST00000392533ZEB1chr1031608221+TAOK3chr12118651915-0.0083059730.99169403
ENST00000560721ENST00000419821ZEB1chr1031608221+TAOK3chr12118651915-0.0085068770.99149317
ENST00000560721ENST00000392533ZEB1chr1031608221+TAOK3chr12118651915-0.0085068770.99149317
ENST00000542815ENST00000419821ZEB1chr1031608221+TAOK3chr12118651915-0.0086107240.99138933
ENST00000542815ENST00000392533ZEB1chr1031608221+TAOK3chr12118651915-0.0086107240.99138933

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Fusion Genomic Features for ZEB1-TAOK3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZEB1-TAOK3


check button Go to

FGviewer for the breakpoints of chr10:31608221-chr12:118651915

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTAOK3chr10:31608221chr12:118651915ENST00000392533821452_502214.33333333333334899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000392533821548_649214.33333333333334899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000392533821754_879214.33333333333334899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000419821821452_502214.33333333333334899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000419821821548_649214.33333333333334899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000419821821754_879214.33333333333334899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000392533821343_393214.33333333333334899.0Compositional biasNote=Ser-rich
TgeneTAOK3chr10:31608221chr12:118651915ENST00000419821821343_393214.33333333333334899.0Compositional biasNote=Ser-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19989_112419.3333333333333321125.0Compositional biasNote=Glu-rich (acidic)
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19989_112419.3333333333333321126.0Compositional biasNote=Glu-rich (acidic)
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19989_112401109.0Compositional biasNote=Glu-rich (acidic)
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18989_112419.3333333333333321058.0Compositional biasNote=Glu-rich (acidic)
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18989_112419.3333333333333321105.0Compositional biasNote=Glu-rich (acidic)
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19581_64019.3333333333333321125.0DNA bindingNote=Homeobox%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19581_64019.3333333333333321126.0DNA bindingNote=Homeobox%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19581_64001109.0DNA bindingNote=Homeobox%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18581_64019.3333333333333321058.0DNA bindingNote=Homeobox%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18581_64019.3333333333333321105.0DNA bindingNote=Homeobox%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19170_19319.3333333333333321125.0Zinc fingerC2H2-type 1
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19200_22219.3333333333333321125.0Zinc fingerC2H2-type 2
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19240_26219.3333333333333321125.0Zinc fingerC2H2-type 3
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19268_29219.3333333333333321125.0Zinc fingerC2H2-type 4%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19904_92619.3333333333333321125.0Zinc fingerC2H2-type 5
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19932_95419.3333333333333321125.0Zinc fingerC2H2-type 6
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19960_98119.3333333333333321125.0Zinc fingerC2H2-type 7%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19170_19319.3333333333333321126.0Zinc fingerC2H2-type 1
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19200_22219.3333333333333321126.0Zinc fingerC2H2-type 2
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19240_26219.3333333333333321126.0Zinc fingerC2H2-type 3
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19268_29219.3333333333333321126.0Zinc fingerC2H2-type 4%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19904_92619.3333333333333321126.0Zinc fingerC2H2-type 5
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19932_95419.3333333333333321126.0Zinc fingerC2H2-type 6
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19960_98119.3333333333333321126.0Zinc fingerC2H2-type 7%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19170_19301109.0Zinc fingerC2H2-type 1
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19200_22201109.0Zinc fingerC2H2-type 2
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19240_26201109.0Zinc fingerC2H2-type 3
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19268_29201109.0Zinc fingerC2H2-type 4%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19904_92601109.0Zinc fingerC2H2-type 5
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19932_95401109.0Zinc fingerC2H2-type 6
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19960_98101109.0Zinc fingerC2H2-type 7%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18170_19319.3333333333333321058.0Zinc fingerC2H2-type 1
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18200_22219.3333333333333321058.0Zinc fingerC2H2-type 2
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18240_26219.3333333333333321058.0Zinc fingerC2H2-type 3
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18268_29219.3333333333333321058.0Zinc fingerC2H2-type 4%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18904_92619.3333333333333321058.0Zinc fingerC2H2-type 5
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18932_95419.3333333333333321058.0Zinc fingerC2H2-type 6
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18960_98119.3333333333333321058.0Zinc fingerC2H2-type 7%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18170_19319.3333333333333321105.0Zinc fingerC2H2-type 1
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18200_22219.3333333333333321105.0Zinc fingerC2H2-type 2
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18240_26219.3333333333333321105.0Zinc fingerC2H2-type 3
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18268_29219.3333333333333321105.0Zinc fingerC2H2-type 4%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18904_92619.3333333333333321105.0Zinc fingerC2H2-type 5
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18932_95419.3333333333333321105.0Zinc fingerC2H2-type 6
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18960_98119.3333333333333321105.0Zinc fingerC2H2-type 7%3B atypical
TgeneTAOK3chr10:31608221chr12:118651915ENST0000039253382124_277214.33333333333334899.0DomainProtein kinase
TgeneTAOK3chr10:31608221chr12:118651915ENST0000041982182124_277214.33333333333334899.0DomainProtein kinase
TgeneTAOK3chr10:31608221chr12:118651915ENST0000039253382130_38214.33333333333334899.0Nucleotide bindingATP
TgeneTAOK3chr10:31608221chr12:118651915ENST0000041982182130_38214.33333333333334899.0Nucleotide bindingATP


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Fusion Gene Sequence for ZEB1-TAOK3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000320985_ENST00000419821_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(transcript)=3418nt_BP=168nt
GTAAACCAGGTGCGGTGGGGAGGGGGGAGGGGTGGAGGCGGAGGGGTGGGGGGGAAGGGGGAGGGAGGGGGAGGAGGTGACTCGAGCATT
TAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGC
CGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACT
CCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGAC
GAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGA
AAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACA
GGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGG
AAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAG
ATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACT
ACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGG
AACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGC
ACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCA
TAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCT
TAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGC
AAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACG
ACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGA
GGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGA
AGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACA
GAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAG
TACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAG
ATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATG
AGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGC
AAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGG
AGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGA
GCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAA
AAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCT
TACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCT
GGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTT
TTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCA
AAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATT
TTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGT
GATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCT
GGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTC
ACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATA
TTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAG
TTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGC
ATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAA

>In-frame_ENST00000320985_ENST00000419821_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(amino acids)=703AA_start in transcript=110_stop in transcript=2221
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>In-frame_ENST00000320985_ENST00000392533_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(transcript)=3418nt_BP=168nt
GTAAACCAGGTGCGGTGGGGAGGGGGGAGGGGTGGAGGCGGAGGGGTGGGGGGGAAGGGGGAGGGAGGGGGAGGAGGTGACTCGAGCATT
TAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGC
CGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACT
CCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGAC
GAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGA
AAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACA
GGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGG
AAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAG
ATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACT
ACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGG
AACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGC
ACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCA
TAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCT
TAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGC
AAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACG
ACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGA
GGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGA
AGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACA
GAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAG
TACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAG
ATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATG
AGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGC
AAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGG
AGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGA
GCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAA
AAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCT
TACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCT
GGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTT
TTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCA
AAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATT
TTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGT
GATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCT
GGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTC
ACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATA
TTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAG
TTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGC
ATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAA

>In-frame_ENST00000320985_ENST00000392533_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(amino acids)=703AA_start in transcript=110_stop in transcript=2221
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>In-frame_ENST00000361642_ENST00000419821_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(transcript)=3371nt_BP=121nt
GGGGGGGAAGGGGGAGGGAGGGGGAGGAGGTGACTCGAGCATTTAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGC
AGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGCCGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCC
CAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACTCCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAA
AGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAA
GATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCA
CAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCC
GTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGAC
GAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCT
GAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTT
ACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAG
CTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCG
TCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAG
CAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAA
GAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCT
GAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCAC
GAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAG
TCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAA
AACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCC
ATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTT
ACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAG
AGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAG
GAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGA
GTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTA
TTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAG
GAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCAC
ATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTC
CATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTAT
TGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGC
TTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCG
CAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTT
ATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGG
GGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATC
ATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTT
GTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCC
TGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCT
CCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGAT
GAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTC

>In-frame_ENST00000361642_ENST00000419821_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(amino acids)=703AA_start in transcript=63_stop in transcript=2174
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>In-frame_ENST00000361642_ENST00000392533_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(transcript)=3371nt_BP=121nt
GGGGGGGAAGGGGGAGGGAGGGGGAGGAGGTGACTCGAGCATTTAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGC
AGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGCCGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCC
CAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACTCCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAA
AGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAA
GATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCA
CAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCC
GTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGAC
GAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCT
GAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTT
ACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAG
CTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCG
TCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAG
CAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAA
GAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCT
GAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCAC
GAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAG
TCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAA
AACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCC
ATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTT
ACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAG
AGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAG
GAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGA
GTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTA
TTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAG
GAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCAC
ATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTC
CATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTAT
TGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGC
TTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCG
CAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTT
ATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGG
GGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATC
ATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTT
GTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCC
TGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCT
CCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGAT
GAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTC

>In-frame_ENST00000361642_ENST00000392533_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(amino acids)=703AA_start in transcript=63_stop in transcript=2174
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>In-frame_ENST00000560721_ENST00000419821_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(transcript)=3331nt_BP=81nt
ATTTAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGA
AGCCGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAG
ACTCCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTC
GACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAA
TGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGA
ACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGC
AGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGA
AAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCC
ACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGC
GGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACG
AGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTA
TCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTT
TCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGA
AGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACT
ACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAA
AGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTAC
AGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGC
ACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCA
AAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGA
AAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAG
ATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGA
TGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAG
AGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGG
AGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAA
AAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTC
TCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGT
GCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACA
GTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAA
GCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTT
ATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAAT
TGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCT
GCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAG
CTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTC
ATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTG
GAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATAT
TGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAA
AAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTCAGAGCTTTTAATTATATTTGTAAATAAAAGTGTTCATCAC

>In-frame_ENST00000560721_ENST00000419821_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(amino acids)=703AA_start in transcript=23_stop in transcript=2134
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>In-frame_ENST00000560721_ENST00000392533_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(transcript)=3331nt_BP=81nt
ATTTAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGA
AGCCGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAG
ACTCCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTC
GACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAA
TGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGA
ACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGC
AGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGA
AAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCC
ACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGC
GGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACG
AGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTA
TCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTT
TCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGA
AGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACT
ACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAA
AGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTAC
AGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGC
ACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCA
AAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGA
AAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAG
ATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGA
TGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAG
AGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGG
AGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAA
AAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTC
TCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGT
GCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACA
GTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAA
GCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTT
ATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAAT
TGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCT
GCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAG
CTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTC
ATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTG
GAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATAT
TGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAA
AAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTCAGAGCTTTTAATTATATTTGTAAATAAAAGTGTTCATCAC

>In-frame_ENST00000560721_ENST00000392533_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(amino acids)=703AA_start in transcript=23_stop in transcript=2134
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>In-frame_ENST00000542815_ENST00000419821_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(transcript)=3321nt_BP=71nt
AAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGCCGCCCCT
TTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACTCCTTTAG
GAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGACGAGACCG
GCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAAT
ACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAAT
GGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCAT
GGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGT
ATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAA
CAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGAT
GTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCT
CAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAA
GGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAG
TCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCG
GATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAA
TTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCA
GAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACG
CATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCA
TGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGAC
CAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCA
GACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCA
AGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGA
GGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGC
TGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAG
AATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAA
AAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTT
ACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAA
ACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAA
AACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATA
ATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTT
TTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTAC
ATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGA
GTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAAT
CCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATT
TTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACA
CTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTC
ACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACA

>In-frame_ENST00000542815_ENST00000419821_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(amino acids)=703AA_start in transcript=13_stop in transcript=2124
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>In-frame_ENST00000542815_ENST00000392533_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(transcript)=3321nt_BP=71nt
AAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGCCGCCCCT
TTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACTCCTTTAG
GAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGACGAGACCG
GCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAAT
ACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAAT
GGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCAT
GGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGT
ATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAA
CAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGAT
GTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCT
CAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAA
GGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAG
TCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCG
GATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAA
TTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCA
GAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACG
CATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCA
TGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGAC
CAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCA
GACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCA
AGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGA
GGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGC
TGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAG
AATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAA
AAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTT
ACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAA
ACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAA
AACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATA
ATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTT
TTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTAC
ATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGA
GTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAAT
CCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATT
TTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACA
CTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTC
ACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACA

>In-frame_ENST00000542815_ENST00000392533_TCGA-CD-A4MJ_ZEB1_chr10_31608221_+_TAOK3_chr12_118651915_length(amino acids)=703AA_start in transcript=13_stop in transcript=2124
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZEB1-TAOK3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZEB1-TAOK3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZEB1-TAOK3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneZEB1C2750448CORNEAL DYSTROPHY, FUCHS ENDOTHELIAL, 64CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneZEB1C0006142Malignant neoplasm of breast2CTD_human
HgeneZEB1C0339284Polymorphous corneal dystrophy2ORPHANET
HgeneZEB1C0678222Breast Carcinoma2CTD_human
HgeneZEB1C1257931Mammary Neoplasms, Human2CTD_human
HgeneZEB1C1458155Mammary Neoplasms2CTD_human
HgeneZEB1C1836724CORNEAL DYSTROPHY, POSTERIOR POLYMORPHOUS, 3 (disorder)2CTD_human;GENOMICS_ENGLAND
HgeneZEB1C4704874Mammary Carcinoma, Human2CTD_human
HgeneZEB1C0007621Neoplastic Cell Transformation1CTD_human
HgeneZEB1C0014170Endometrial Neoplasms1CTD_human
HgeneZEB1C0016781Fuchs Endothelial Dystrophy1GENOMICS_ENGLAND;ORPHANET
HgeneZEB1C0027626Neoplasm Invasiveness1CTD_human
HgeneZEB1C0029172Oral Submucous Fibrosis1CTD_human
HgeneZEB1C0036920Sezary Syndrome1CTD_human
HgeneZEB1C0079773Lymphoma, T-Cell, Cutaneous1CTD_human
HgeneZEB1C0151744Myocardial Ischemia1CTD_human
HgeneZEB1C0235874Disease Exacerbation1CTD_human
HgeneZEB1C0238463Papillary thyroid carcinoma1CTD_human
HgeneZEB1C0376407Granulomatous Slack Skin1CTD_human
HgeneZEB1C0476089Endometrial Carcinoma1CTD_human
HgeneZEB1C0919267ovarian neoplasm1CTD_human
HgeneZEB1C1140680Malignant neoplasm of ovary1CTD_human
HgeneZEB1C3501843Nonmedullary Thyroid Carcinoma1CTD_human
HgeneZEB1C3501844Familial Nonmedullary Thyroid Cancer1CTD_human