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Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:ZNF461-AKT1 (FusionGDB2 ID:101465) |
Fusion Gene Summary for ZNF461-AKT1 |
Fusion gene summary |
Fusion gene information | Fusion gene name: ZNF461-AKT1 | Fusion gene ID: 101465 | Hgene | Tgene | Gene symbol | ZNF461 | AKT1 | Gene ID | 92283 | 207 |
Gene name | zinc finger protein 461 | AKT serine/threonine kinase 1 | |
Synonyms | GIOT-1|GIOT1|HZF28 | AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA | |
Cytomap | 19q13.12 | 14q32.33 | |
Type of gene | protein-coding | protein-coding | |
Description | zinc finger protein 461gonadotropin-inducible ovary transcription repressor 1zinc finger protein 28 | RAC-alpha serine/threonine-protein kinaseAKT1mPKB alphaRAC-PK-alphaprotein kinase B alphaproto-oncogene c-Aktrac protein kinase alphaserine-threonine protein kinasev-akt murine thymoma viral oncogene homolog 1v-akt murine thymoma viral oncogene-l | |
Modification date | 20200313 | 20200329 | |
UniProtAcc | . | Q96B36 | |
Ensembl transtripts involved in fusion gene | ENST00000588268, ENST00000360357, ENST00000540605, | ENST00000554581, ENST00000407796, ENST00000349310, ENST00000402615, ENST00000555528, ENST00000554848, ENST00000555458, ENST00000554192, ENST00000544168, ENST00000554585, | |
Fusion gene scores | * DoF score | 3 X 3 X 3=27 | 3 X 3 X 3=27 |
# samples | 4 | 3 | |
** MAII score | log2(4/27*10)=0.567040592723894 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: ZNF461 [Title/Abstract] AND AKT1 [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | ZNF461(37147350)-AKT1(105246553), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. | ZNF461-AKT1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF. ZNF461-AKT1 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF. ZNF461-AKT1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. ZNF461-AKT1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF. ZNF461-AKT1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Tgene | AKT1 | GO:0001934 | positive regulation of protein phosphorylation | 19057511 |
Tgene | AKT1 | GO:0006468 | protein phosphorylation | 11994271|14749367|23431171 |
Tgene | AKT1 | GO:0007173 | epidermal growth factor receptor signaling pathway | 20878056 |
Tgene | AKT1 | GO:0016310 | phosphorylation | 20333297 |
Tgene | AKT1 | GO:0018105 | peptidyl-serine phosphorylation | 16139227 |
Tgene | AKT1 | GO:0018107 | peptidyl-threonine phosphorylation | 20605787 |
Tgene | AKT1 | GO:0030307 | positive regulation of cell growth | 19203586 |
Tgene | AKT1 | GO:0032079 | positive regulation of endodeoxyribonuclease activity | 20605787 |
Tgene | AKT1 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 19667065 |
Tgene | AKT1 | GO:0035556 | intracellular signal transduction | 14749367 |
Tgene | AKT1 | GO:0035655 | interleukin-18-mediated signaling pathway | 21321938 |
Tgene | AKT1 | GO:0043066 | negative regulation of apoptotic process | 19203586 |
Tgene | AKT1 | GO:0043536 | positive regulation of blood vessel endothelial cell migration | 20011604 |
Tgene | AKT1 | GO:0048661 | positive regulation of smooth muscle cell proliferation | 21321938 |
Tgene | AKT1 | GO:0051091 | positive regulation of DNA-binding transcription factor activity | 19057511 |
Tgene | AKT1 | GO:0070141 | response to UV-A | 18483258 |
Fusion gene breakpoints across ZNF461 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene breakpoints across AKT1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | PRAD | TCGA-G9-6354-01A | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
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Fusion Gene ORF analysis for ZNF461-AKT1 |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
Frame-shift | ENST00000588268 | ENST00000554581 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
Frame-shift | ENST00000588268 | ENST00000407796 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
Frame-shift | ENST00000588268 | ENST00000349310 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
Frame-shift | ENST00000588268 | ENST00000402615 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
Frame-shift | ENST00000588268 | ENST00000555528 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
Frame-shift | ENST00000588268 | ENST00000554848 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
5CDS-intron | ENST00000588268 | ENST00000555458 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
5CDS-intron | ENST00000588268 | ENST00000554192 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
5CDS-intron | ENST00000588268 | ENST00000544168 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
5CDS-intron | ENST00000588268 | ENST00000554585 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
Frame-shift | ENST00000360357 | ENST00000554581 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
Frame-shift | ENST00000360357 | ENST00000407796 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
Frame-shift | ENST00000360357 | ENST00000349310 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
Frame-shift | ENST00000360357 | ENST00000402615 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
Frame-shift | ENST00000360357 | ENST00000555528 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
Frame-shift | ENST00000360357 | ENST00000554848 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
5CDS-intron | ENST00000360357 | ENST00000555458 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
5CDS-intron | ENST00000360357 | ENST00000554192 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
5CDS-intron | ENST00000360357 | ENST00000544168 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
5CDS-intron | ENST00000360357 | ENST00000554585 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
intron-3CDS | ENST00000540605 | ENST00000554581 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
intron-3CDS | ENST00000540605 | ENST00000407796 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
intron-3CDS | ENST00000540605 | ENST00000349310 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
intron-3CDS | ENST00000540605 | ENST00000402615 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
intron-3CDS | ENST00000540605 | ENST00000555528 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
intron-3CDS | ENST00000540605 | ENST00000554848 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
intron-intron | ENST00000540605 | ENST00000555458 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
intron-intron | ENST00000540605 | ENST00000554192 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
intron-intron | ENST00000540605 | ENST00000544168 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
intron-intron | ENST00000540605 | ENST00000554585 | ZNF461 | chr19 | 37147350 | - | AKT1 | chr14 | 105246553 | - |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
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Fusion Genomic Features for ZNF461-AKT1 |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for ZNF461-AKT1 |
Go to FGviewer for the breakpoints of :-: - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
. | AKT1 |
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Subunit of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, AKT1S1 negatively regulates mTOR activity in a manner that is dependent on its phosphorylation state and binding to 14-3-3 proteins. Inhibits RHEB-GTP-dependent mTORC1 activation. Substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. May also play a role in nerve growth factor-mediated neuroprotection. {ECO:0000269|PubMed:16174443, ECO:0000269|PubMed:17277771, ECO:0000269|PubMed:17386266}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for ZNF461-AKT1 |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
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Fusion Gene PPI Analysis for ZNF461-AKT1 |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ZNF461-AKT1 |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ZNF461-AKT1 |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Tgene | AKT1 | C0005586 | Bipolar Disorder | 5 | PSYGENET |
Tgene | AKT1 | C0011570 | Mental Depression | 5 | PSYGENET |
Tgene | AKT1 | C0011581 | Depressive disorder | 5 | PSYGENET |
Tgene | AKT1 | C0036341 | Schizophrenia | 5 | CTD_human;GENOMICS_ENGLAND |
Tgene | AKT1 | C0006142 | Malignant neoplasm of breast | 3 | CGI;CTD_human;GENOMICS_ENGLAND;UNIPROT |
Tgene | AKT1 | C0024121 | Lung Neoplasms | 3 | CTD_human |
Tgene | AKT1 | C0085261 | Proteus Syndrome | 3 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT |
Tgene | AKT1 | C0242379 | Malignant neoplasm of lung | 3 | CTD_human |
Tgene | AKT1 | C1140680 | Malignant neoplasm of ovary | 3 | CGI;CTD_human;GENOMICS_ENGLAND |
Tgene | AKT1 | C0021368 | Inflammation | 2 | CTD_human |
Tgene | AKT1 | C0033578 | Prostatic Neoplasms | 2 | CTD_human |
Tgene | AKT1 | C0376358 | Malignant neoplasm of prostate | 2 | CTD_human |
Tgene | AKT1 | C0525045 | Mood Disorders | 2 | PSYGENET |
Tgene | AKT1 | C0919267 | ovarian neoplasm | 2 | CGI;CTD_human |
Tgene | AKT1 | C0006868 | Cannabis Abuse | 1 | CTD_human |
Tgene | AKT1 | C0006870 | Cannabis Dependence | 1 | CTD_human |
Tgene | AKT1 | C0007114 | Malignant neoplasm of skin | 1 | CTD_human |
Tgene | AKT1 | C0007137 | Squamous cell carcinoma | 1 | CTD_human |
Tgene | AKT1 | C0009402 | Colorectal Carcinoma | 1 | CTD_human;GENOMICS_ENGLAND |
Tgene | AKT1 | C0014544 | Epilepsy | 1 | CTD_human |
Tgene | AKT1 | C0016059 | Fibrosis | 1 | CTD_human |
Tgene | AKT1 | C0018553 | Hamartoma Syndrome, Multiple | 1 | ORPHANET |
Tgene | AKT1 | C0018614 | Hashish Abuse | 1 | CTD_human |
Tgene | AKT1 | C0018800 | Cardiomegaly | 1 | CTD_human |
Tgene | AKT1 | C0020507 | Hyperplasia | 1 | CTD_human |
Tgene | AKT1 | C0023487 | Acute Promyelocytic Leukemia | 1 | CTD_human |
Tgene | AKT1 | C0024809 | Marijuana Abuse | 1 | CTD_human |
Tgene | AKT1 | C0025286 | Meningioma | 1 | CGI;CTD_human |
Tgene | AKT1 | C0026846 | Muscular Atrophy | 1 | CTD_human |
Tgene | AKT1 | C0028754 | Obesity | 1 | CTD_human |
Tgene | AKT1 | C0030193 | Pain | 1 | CTD_human |
Tgene | AKT1 | C0032580 | Adenomatous Polyposis Coli | 1 | CTD_human |
Tgene | AKT1 | C0032927 | Precancerous Conditions | 1 | CTD_human |
Tgene | AKT1 | C0033141 | Cardiomyopathies, Primary | 1 | CTD_human |
Tgene | AKT1 | C0033937 | Psychoses, Drug | 1 | CTD_human |
Tgene | AKT1 | C0033941 | Psychoses, Substance-Induced | 1 | CTD_human |
Tgene | AKT1 | C0036529 | Myocardial Diseases, Secondary | 1 | CTD_human |
Tgene | AKT1 | C0037286 | Skin Neoplasms | 1 | CTD_human |
Tgene | AKT1 | C0079772 | T-Cell Lymphoma | 1 | CTD_human |
Tgene | AKT1 | C0086237 | Epilepsy, Cryptogenic | 1 | CTD_human |
Tgene | AKT1 | C0205834 | Meningiomas, Multiple | 1 | CTD_human |
Tgene | AKT1 | C0234230 | Pain, Burning | 1 | CTD_human |
Tgene | AKT1 | C0234238 | Ache | 1 | CTD_human |
Tgene | AKT1 | C0234254 | Radiating pain | 1 | CTD_human |
Tgene | AKT1 | C0236018 | Aura | 1 | CTD_human |
Tgene | AKT1 | C0236733 | Amphetamine-Related Disorders | 1 | CTD_human |
Tgene | AKT1 | C0236735 | Cannabis-Related Disorder | 1 | CTD_human |
Tgene | AKT1 | C0236804 | Amphetamine Addiction | 1 | CTD_human |
Tgene | AKT1 | C0236807 | Amphetamine Abuse | 1 | CTD_human |
Tgene | AKT1 | C0259785 | Malignant Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0270948 | Neurogenic Muscular Atrophy | 1 | CTD_human |
Tgene | AKT1 | C0281784 | Benign Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0282313 | Condition, Preneoplastic | 1 | CTD_human |
Tgene | AKT1 | C0334605 | Meningothelial meningioma | 1 | CTD_human |
Tgene | AKT1 | C0334606 | Fibrous Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0334607 | Psammomatous Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0334608 | Angiomatous Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0334609 | Hemangioblastic Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0334610 | Hemangiopericytic Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0334611 | Transitional Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0347515 | Spinal Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0349604 | Intracranial Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0428791 | Aortic valve calcification | 1 | CTD_human |
Tgene | AKT1 | C0431121 | Clear Cell Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0457190 | Xanthomatous Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0458257 | Pain, Splitting | 1 | CTD_human |
Tgene | AKT1 | C0458259 | Pain, Crushing | 1 | CTD_human |
Tgene | AKT1 | C0678222 | Breast Carcinoma | 1 | CGI;CTD_human |
Tgene | AKT1 | C0751111 | Awakening Epilepsy | 1 | CTD_human |
Tgene | AKT1 | C0751303 | Cerebral Convexity Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0751304 | Parasagittal Meningioma | 1 | CTD_human |
Tgene | AKT1 | C0751407 | Pain, Migratory | 1 | CTD_human |
Tgene | AKT1 | C0751408 | Suffering, Physical | 1 | CTD_human |
Tgene | AKT1 | C0878544 | Cardiomyopathies | 1 | CTD_human |
Tgene | AKT1 | C1168401 | Squamous cell carcinoma of the head and neck | 1 | CTD_human |
Tgene | AKT1 | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
Tgene | AKT1 | C1334261 | Intraorbital Meningioma | 1 | CTD_human |
Tgene | AKT1 | C1334271 | Intraventricular Meningioma | 1 | CTD_human |
Tgene | AKT1 | C1335107 | Olfactory Groove Meningioma | 1 | CTD_human |
Tgene | AKT1 | C1383860 | Cardiac Hypertrophy | 1 | CTD_human |
Tgene | AKT1 | C1384406 | Secretory meningioma | 1 | CTD_human |
Tgene | AKT1 | C1384408 | Microcystic meningioma | 1 | CTD_human |
Tgene | AKT1 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
Tgene | AKT1 | C1527197 | Angioblastic Meningioma | 1 | CTD_human |
Tgene | AKT1 | C1565950 | Posterior Fossa Meningioma | 1 | CTD_human |
Tgene | AKT1 | C1565951 | Sphenoid Wing Meningioma | 1 | CTD_human |
Tgene | AKT1 | C1623038 | Cirrhosis | 1 | CTD_human |
Tgene | AKT1 | C2713442 | Polyposis, Adenomatous Intestinal | 1 | CTD_human |
Tgene | AKT1 | C2713443 | Familial Intestinal Polyposis | 1 | CTD_human |
Tgene | AKT1 | C3163622 | Papillary Meningioma | 1 | CTD_human |
Tgene | AKT1 | C3554519 | COWDEN SYNDROME 6 | 1 | CTD_human;GENOMICS_ENGLAND;UNIPROT |
Tgene | AKT1 | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |