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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ZNF652-CD300LD (FusionGDB2 ID:101939)

Fusion Gene Summary for ZNF652-CD300LD

Fusion gene summary

Fusion gene information	Fusion gene name: ZNF652-CD300LD
	Fusion gene ID: 101939
		Hgene	Tgene
	Gene symbol	ZNF652	CD300LD
	Gene ID	22834	100131439
	Gene name	zinc finger protein 652	CD300 molecule like family member d
	Synonyms	-	CD300D\|CLM-4\|CLM-5\|CMRF35-A4\|CMRF35A4
	Cytomap	17q21.32-q21.33	17q25.1
	Type of gene	protein-coding	protein-coding
	Description	zinc finger protein 652	CMRF35-like molecule 5CD300 antigen-like family member DCMRF35-like molecule 4immune receptor CD300d
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000513488, ENST00000362063, ENST00000430262,	ENST00000375352,
Fusion gene scores	* DoF score	8 X 8 X 6=384	1 X 1 X 1=1
	# samples	8	1
	** MAII score	log2(8/384*10)=-2.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(1/1*10)=3.32192809488736
Context	PubMed: ZNF652 [Title/Abstract] AND CD300LD [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ZNF652(47394188)-CD300LD(72578450), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across ZNF652 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CD300LD (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-EW-A1OX-01A	ZNF652	chr17	47394188	-	CD300LD	chr17	72578450	-
ChimerDB4	BRCA	TCGA-EW-A1OX-01A	ZNF652	chr17	47394188	-	CD300LD	chr17	72578450	-

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Fusion Gene ORF analysis for ZNF652-CD300LD

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-3CDS	ENST00000513488	ENST00000375352	ZNF652	chr17	47394188	-	CD300LD	chr17	72578450	-
In-frame	ENST00000362063	ENST00000375352	ZNF652	chr17	47394188	-	CD300LD	chr17	72578450	-
In-frame	ENST00000430262	ENST00000375352	ZNF652	chr17	47394188	-	CD300LD	chr17	72578450	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000362063	ZNF652	chr17	47394188	-	ENST00000375352	CD300LD	chr17	72578450	-	2062	1219	292	1374	360
ENST00000430262	ZNF652	chr17	47394188	-	ENST00000375352	CD300LD	chr17	72578450	-	2209	1366	439	1521	360

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000362063	ENST00000375352	ZNF652	chr17	47394188	-	CD300LD	chr17	72578450	-	0.003301606	0.9966983
ENST00000430262	ENST00000375352	ZNF652	chr17	47394188	-	CD300LD	chr17	72578450	-	0.004041189	0.99595875

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Fusion Genomic Features for ZNF652-CD300LD

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZNF652-CD300LD

Go to
FGviewer for the breakpoints of chr17:47394188-chr17:72578450
.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.	FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000362063

74_183

300.0

607.0

Compositional bias

Note=Glu-rich

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000430262

74_183

300.0

607.0

Compositional bias

Note=Glu-rich

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000362063

245_268

300.0

607.0

Zinc finger

C2H2-type 1

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000362063

272_294

300.0

607.0

Zinc finger

C2H2-type 2%3B degenerate

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000430262

245_268

300.0

607.0

Zinc finger

C2H2-type 1

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000430262

272_294

300.0

607.0

Zinc finger

C2H2-type 2%3B degenerate

Tgene

CD300LD

chr17:47394188

chr17:72578450

ENST00000375352

136_139

126.33333333333333

195.0

Compositional bias

Note=Poly-Thr

Tgene

CD300LD

chr17:47394188

chr17:72578450

ENST00000375352

187_194

126.33333333333333

195.0

Topological domain

Cytoplasmic

Tgene

CD300LD

chr17:47394188

chr17:72578450

ENST00000375352

166_186

126.33333333333333

195.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000362063

497_574

300.0

607.0

Compositional bias

Note=Pro-rich

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000430262

497_574

300.0

607.0

Compositional bias

Note=Pro-rich

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000362063

299_322

300.0

607.0

Zinc finger

C2H2-type 3

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000362063

329_351

300.0

607.0

Zinc finger

C2H2-type 4

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000362063

357_379

300.0

607.0

Zinc finger

C2H2-type 5

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000362063

385_407

300.0

607.0

Zinc finger

C2H2-type 6

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000362063

413_435

300.0

607.0

Zinc finger

C2H2-type 7

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000362063

441_463

300.0

607.0

Zinc finger

C2H2-type 8

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000362063

469_492

300.0

607.0

Zinc finger

C2H2-type 9%3B degenerate

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000430262

299_322

300.0

607.0

Zinc finger

C2H2-type 3

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000430262

329_351

300.0

607.0

Zinc finger

C2H2-type 4

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000430262

357_379

300.0

607.0

Zinc finger

C2H2-type 5

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000430262

385_407

300.0

607.0

Zinc finger

C2H2-type 6

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000430262

413_435

300.0

607.0

Zinc finger

C2H2-type 7

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000430262

441_463

300.0

607.0

Zinc finger

C2H2-type 8

Hgene

ZNF652

chr17:47394188

chr17:72578450

ENST00000430262

469_492

300.0

607.0

Zinc finger

C2H2-type 9%3B degenerate

Tgene

CD300LD

chr17:47394188

chr17:72578450

ENST00000375352

19_125

126.33333333333333

195.0

Domain

Note=Ig-like V-type

Tgene

CD300LD

chr17:47394188

chr17:72578450

ENST00000375352

19_165

126.33333333333333

195.0

Topological domain

Extracellular

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Fusion Gene Sequence for ZNF652-CD300LD

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>In-frame_ENST00000362063_ENST00000375352_TCGA-EW-A1OX-01A_ZNF652_chr17_47394188_-_CD300LD_chr17_72578450_length(transcript)=2062nt_BP=1219nt
GCGGGGAGCCGGCGGTTATCTGGGCGGCGGAGCGCTCACAATGTGGCAGGAGACAGAAAAGATAAGATGCTCCCAAGTCCCTTGCAGCTC
TCTTCAGAAGAAAAATCACTAGTGCTCTGCTCTTGCCATAATACCAAACCTTTTTGACTCATGCTTTGGTGCTGCAACACTGGAAGAATT
GCACACAGTTTCCAGGAATATCTTTTTTTCATTTGAGTGATTCTTTGTGGATGAGAAAAGATTTGAGTCTTAATAATTACCTTGTTTTAA
AGCTATTTCTTTATAGTCTGAACTGTTTAATAAATTGGGCCACTTACCAATGAGCCACACAGCCAGTTCTTGTCAGGAGCTGGTTGAAAA
CTGTGCTGTGCATGTAGCAGGAATGGCACAAGAAGATAGCCGTCGTGGTCAAGTGCCATCTTCCTTTTATCATGGTGCCAACCAAGAACT
TGACCTGTCCACCAAAGTGTACAAAAGGGAATCAGGAAGTCCTTATTCTGTGTTAGTGGACACCAAGATGAGCAAACCGCATCTCCATGA
AACAGAAGAACAGCCATATTTCAGGGAGACAAGAGCAGTGTCTGACGTGCATGCTGTTAAGGAAGACCGGGAGAATTCTGATGACACAGA
GGAGGAAGAGGAAGAAGTCTCTTACAAAAGGGAGCAGATCATAGTGGAGGTAAACCTTAATAATCAAACATTAAATGTATCTAAAGGGGA
AAAGGGTGTCTCTTCTCAGTCCAAAGAGACTCCTGTTCTTAAGACAAGCAGTGAGGAGGAAGAGGAAGAGAGTGAGGAAGAGGCCACAGA
TGACAGCAATGACTATGGAGAGAATGAAAAGCAGAAGAAAAAGGAGAAGATAGTAGAGAAAGTCAGCGTTACACAAAGGAGAACCAGGAG
AGCTGCCTCTGTTGCCGCAGCTACCACTTCCCCTACTCCCAGAACTACAAGAGGTCGTAGGAAGAGTGTAGAGCCACCTAAGCGTAAGAA
GCGGGCCACAAAGGAGCCCAAAGCACCAGTCCAGAAAGCTAAGTGTGAAGAGAAAGAGACTCTGACCTGTGAGAAGTGCCCCAGGGTATT
TAACACTCGCTGGTACCTGGAGAAGCACATGAACGTTACTCATAGGCGCATGCAGATTTGTGATAAATGTGGCAAGAAGTTTGTCCTGGA
AAGTGAGCTGTCCCTTCACCAGCAAACAGACTGTGAAAAAAACATTCAGGCACACAAACTGCAGTCTCAGAATGGACAACCACAACAGCA
AGCCTGGCTTTCACAGCTGCAGCCACCCAGAAGACCAGCAGCCCCCTCACCAGGTCCCCGCTCAAGAGCACCCACTTCCTGTTCCTGTTC
CTCCTGGAGCTGCCTCTGCTCCTGAGCATGCTGGGGACCGTCCTCTGGGTAAACAGACCACAAAGAAGGTCTTGAAGGAGGAGGAGTCAG
CCCGATGATGAGAGTCCCAATGCCCATTGACGTCCTGTCCAGGGCGAAAGGCCCTCCCACAGAAGAAAAAACATTTTCTTTTCTCTTCTT
TTTTTCTTTCTAGAGATAGAGTCTTGCTCTGTCACCCAGGCTGGAATGCAATGGTGTAATCTCTGCTCACTGCAACTTTCCCCTCCCAGG
CTCAAGCGATCCTCCTGCCTCAACCTCCAGAGTAGCTGGGGCTACAGGCACATGCCACCACCCCCAGCTAATTTTTAAATTTTTTTGTAG
AGATGGGCTTCCACCACGTTGCCCAGGCTGGTCTCGAACTCTTGACCTCAAGAGATCCTCCCGCTTCGCCTCCCAAAGTGGTGGGATTAC
AGGTGTGAGCCACCGCACCTGGCAGAAAAACAACATTTCTATGGGGAATTGACTGTGGTTCTAGAGGCAGTGCTGGCCCCAGCTTCAGGG
AACAGCCTCCTAGTCCCCTATCTCCTGCAGCCGTGCCACCTGGGGCTATTCCCTTCTCTGCACAGTCCCTGGGGCCTGACAGAGCCCTTC

>In-frame_ENST00000362063_ENST00000375352_TCGA-EW-A1OX-01A_ZNF652_chr17_47394188_-_CD300LD_chr17_72578450_length(amino acids)=360AA_start in transcript=292_stop in transcript=1374
MFNKLGHLPMSHTASSCQELVENCAVHVAGMAQEDSRRGQVPSSFYHGANQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPYF
RETRAVSDVHAVKEDRENSDDTEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGE
NEKQKKKEKIVEKVSVTQRRTRRAASVAAATTSPTPRTTRGRRKSVEPPKRKKRATKEPKAPVQKAKCEEKETLTCEKCPRVFNTRWYLE
KHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQAHKLQSQNGQPQQQAWLSQLQPPRRPAAPSPGPRSRAPTSCSCSSWSCLCS

--------------------------------------------------------------
>In-frame_ENST00000430262_ENST00000375352_TCGA-EW-A1OX-01A_ZNF652_chr17_47394188_-_CD300LD_chr17_72578450_length(transcript)=2209nt_BP=1366nt
GGAGCGGCGGCCACGTAGCGCTGCGGCGGCAGCGGCAGCGGCCGAGGCCGGGTCTGAGGAGCGGCCCTGAGGACAGACGTTGGGCAGGGG
GGGAGGGGCTGGCCCAGCCGGCGGTTGTGACTCGAGCGCCGCGGCTGCAGGCCCCCGCCGCAGGGATGGACCGCCGAGGCGGCGGCCGGG
GCGGCGGAGGCGGAGGCGGCCGGCCCGGATAAGATGCTCCCAAGTCCCTTGCAGCTCTCTTCAGAAGAAAAATCACTAGTGCTCTGCTCT
TGCCATAATACCAAACCTTTTTGACTCATGCTTTGGTGCTGCAACACTGGAAGAATTGCACACAGTTTCCAGGAATATCTTTTTTTCATT
TGAGTGATTCTTTGTGGATGAGAAAAGATTTGAGTCTTAATAATTACCTTGTTTTAAAGCTATTTCTTTATAGTCTGAACTGTTTAATAA
ATTGGGCCACTTACCAATGAGCCACACAGCCAGTTCTTGTCAGGAGCTGGTTGAAAACTGTGCTGTGCATGTAGCAGGAATGGCACAAGA
AGATAGCCGTCGTGGTCAAGTGCCATCTTCCTTTTATCATGGTGCCAACCAAGAACTTGACCTGTCCACCAAAGTGTACAAAAGGGAATC
AGGAAGTCCTTATTCTGTGTTAGTGGACACCAAGATGAGCAAACCGCATCTCCATGAAACAGAAGAACAGCCATATTTCAGGGAGACAAG
AGCAGTGTCTGACGTGCATGCTGTTAAGGAAGACCGGGAGAATTCTGATGACACAGAGGAGGAAGAGGAAGAAGTCTCTTACAAAAGGGA
GCAGATCATAGTGGAGGTAAACCTTAATAATCAAACATTAAATGTATCTAAAGGGGAAAAGGGTGTCTCTTCTCAGTCCAAAGAGACTCC
TGTTCTTAAGACAAGCAGTGAGGAGGAAGAGGAAGAGAGTGAGGAAGAGGCCACAGATGACAGCAATGACTATGGAGAGAATGAAAAGCA
GAAGAAAAAGGAGAAGATAGTAGAGAAAGTCAGCGTTACACAAAGGAGAACCAGGAGAGCTGCCTCTGTTGCCGCAGCTACCACTTCCCC
TACTCCCAGAACTACAAGAGGTCGTAGGAAGAGTGTAGAGCCACCTAAGCGTAAGAAGCGGGCCACAAAGGAGCCCAAAGCACCAGTCCA
GAAAGCTAAGTGTGAAGAGAAAGAGACTCTGACCTGTGAGAAGTGCCCCAGGGTATTTAACACTCGCTGGTACCTGGAGAAGCACATGAA
CGTTACTCATAGGCGCATGCAGATTTGTGATAAATGTGGCAAGAAGTTTGTCCTGGAAAGTGAGCTGTCCCTTCACCAGCAAACAGACTG
TGAAAAAAACATTCAGGCACACAAACTGCAGTCTCAGAATGGACAACCACAACAGCAAGCCTGGCTTTCACAGCTGCAGCCACCCAGAAG
ACCAGCAGCCCCCTCACCAGGTCCCCGCTCAAGAGCACCCACTTCCTGTTCCTGTTCCTCCTGGAGCTGCCTCTGCTCCTGAGCATGCTG
GGGACCGTCCTCTGGGTAAACAGACCACAAAGAAGGTCTTGAAGGAGGAGGAGTCAGCCCGATGATGAGAGTCCCAATGCCCATTGACGT
CCTGTCCAGGGCGAAAGGCCCTCCCACAGAAGAAAAAACATTTTCTTTTCTCTTCTTTTTTTCTTTCTAGAGATAGAGTCTTGCTCTGTC
ACCCAGGCTGGAATGCAATGGTGTAATCTCTGCTCACTGCAACTTTCCCCTCCCAGGCTCAAGCGATCCTCCTGCCTCAACCTCCAGAGT
AGCTGGGGCTACAGGCACATGCCACCACCCCCAGCTAATTTTTAAATTTTTTTGTAGAGATGGGCTTCCACCACGTTGCCCAGGCTGGTC
TCGAACTCTTGACCTCAAGAGATCCTCCCGCTTCGCCTCCCAAAGTGGTGGGATTACAGGTGTGAGCCACCGCACCTGGCAGAAAAACAA
CATTTCTATGGGGAATTGACTGTGGTTCTAGAGGCAGTGCTGGCCCCAGCTTCAGGGAACAGCCTCCTAGTCCCCTATCTCCTGCAGCCG
TGCCACCTGGGGCTATTCCCTTCTCTGCACAGTCCCTGGGGCCTGACAGAGCCCTTCTTCCTTCTGAGGTCTCCAATGCAGTAGAAAACA

>In-frame_ENST00000430262_ENST00000375352_TCGA-EW-A1OX-01A_ZNF652_chr17_47394188_-_CD300LD_chr17_72578450_length(amino acids)=360AA_start in transcript=439_stop in transcript=1521
MFNKLGHLPMSHTASSCQELVENCAVHVAGMAQEDSRRGQVPSSFYHGANQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPYF
RETRAVSDVHAVKEDRENSDDTEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGE
NEKQKKKEKIVEKVSVTQRRTRRAASVAAATTSPTPRTTRGRRKSVEPPKRKKRATKEPKAPVQKAKCEEKETLTCEKCPRVFNTRWYLE
KHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQAHKLQSQNGQPQQQAWLSQLQPPRRPAAPSPGPRSRAPTSCSCSSWSCLCS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNF652-CD300LD

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for ZNF652-CD300LD

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ZNF652-CD300LD

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source