FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:ZNF700-RAD23A (FusionGDB2 ID:102054)

Fusion Gene Summary for ZNF700-RAD23A

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF700-RAD23A
Fusion gene ID: 102054
HgeneTgene
Gene symbol

ZNF700

RAD23A

Gene ID

90592

5886

Gene namezinc finger protein 700RAD23 homolog A, nucleotide excision repair protein
Synonyms-HHR23A|HR23A
Cytomap

19p13.2

19p13.13

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 700UV excision repair protein RAD23 homolog ARAD23, yeast homolog, A
Modification date2020031320200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000254321, ENST00000482090, 
ENST00000541222, ENST00000316856, 
ENST00000586534, ENST00000592268, 
ENST00000588826, 
Fusion gene scores* DoF score4 X 2 X 4=3213 X 9 X 9=1053
# samples 515
** MAII scorelog2(5/32*10)=0.643856189774725
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(15/1053*10)=-2.81147103052984
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF700 [Title/Abstract] AND RAD23A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF700(12036088)-RAD23A(13063503), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRAD23A

GO:0006289

nucleotide-excision repair

9372924

TgeneRAD23A

GO:0032434

regulation of proteasomal ubiquitin-dependent protein catabolic process

12643283


check buttonFusion gene breakpoints across ZNF700 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across RAD23A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-HS-A5N9-01AZNF700chr19

12036088

+RAD23Achr19

13063503

+
ChimerDB4SARCTCGA-HS-A5N9ZNF700chr19

12036088

+RAD23Achr19

13063502

+
ChimerDB4SARCTCGA-HS-A5N9-01AZNF700chr19

12036088

+RAD23Achr19

13063503

+
ChimerDB4SARCTCGA-HS-A5N9-01AZNF700chr19

12036087

+RAD23Achr19

13063502

+


Top

Fusion Gene ORF analysis for ZNF700-RAD23A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000254321ENST00000541222ZNF700chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000254321ENST00000316856ZNF700chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000254321ENST00000586534ZNF700chr19

12036088

+RAD23Achr19

13063503

+
5CDS-intronENST00000254321ENST00000592268ZNF700chr19

12036088

+RAD23Achr19

13063503

+
5CDS-intronENST00000254321ENST00000588826ZNF700chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000482090ENST00000541222ZNF700chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000482090ENST00000316856ZNF700chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000482090ENST00000586534ZNF700chr19

12036088

+RAD23Achr19

13063503

+
intron-intronENST00000482090ENST00000592268ZNF700chr19

12036088

+RAD23Achr19

13063503

+
intron-intronENST00000482090ENST00000588826ZNF700chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000254321ENST00000541222ZNF700chr19

12036088

+RAD23Achr19

13063502

+
In-frameENST00000254321ENST00000316856ZNF700chr19

12036088

+RAD23Achr19

13063502

+
In-frameENST00000254321ENST00000586534ZNF700chr19

12036088

+RAD23Achr19

13063502

+
5CDS-intronENST00000254321ENST00000592268ZNF700chr19

12036088

+RAD23Achr19

13063502

+
5CDS-intronENST00000254321ENST00000588826ZNF700chr19

12036088

+RAD23Achr19

13063502

+
intron-3CDSENST00000482090ENST00000541222ZNF700chr19

12036088

+RAD23Achr19

13063502

+
intron-3CDSENST00000482090ENST00000316856ZNF700chr19

12036088

+RAD23Achr19

13063502

+
intron-3CDSENST00000482090ENST00000586534ZNF700chr19

12036088

+RAD23Achr19

13063502

+
intron-intronENST00000482090ENST00000592268ZNF700chr19

12036088

+RAD23Achr19

13063502

+
intron-intronENST00000482090ENST00000588826ZNF700chr19

12036088

+RAD23Achr19

13063502

+
In-frameENST00000254321ENST00000541222ZNF700chr19

12036087

+RAD23Achr19

13063502

+
In-frameENST00000254321ENST00000316856ZNF700chr19

12036087

+RAD23Achr19

13063502

+
In-frameENST00000254321ENST00000586534ZNF700chr19

12036087

+RAD23Achr19

13063502

+
5CDS-intronENST00000254321ENST00000592268ZNF700chr19

12036087

+RAD23Achr19

13063502

+
5CDS-intronENST00000254321ENST00000588826ZNF700chr19

12036087

+RAD23Achr19

13063502

+
intron-3CDSENST00000482090ENST00000541222ZNF700chr19

12036087

+RAD23Achr19

13063502

+
intron-3CDSENST00000482090ENST00000316856ZNF700chr19

12036087

+RAD23Achr19

13063502

+
intron-3CDSENST00000482090ENST00000586534ZNF700chr19

12036087

+RAD23Achr19

13063502

+
intron-intronENST00000482090ENST00000592268ZNF700chr19

12036087

+RAD23Achr19

13063502

+
intron-intronENST00000482090ENST00000588826ZNF700chr19

12036087

+RAD23Achr19

13063502

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000254321ZNF700chr1912036088+ENST00000541222RAD23Achr1913063503+70520653484143
ENST00000254321ZNF700chr1912036088+ENST00000316856RAD23Achr1913063503+1059206845402147
ENST00000254321ZNF700chr1912036088+ENST00000586534RAD23Achr1913063503+1078206845402147
ENST00000254321ZNF700chr1912036088+ENST00000541222RAD23Achr1913063502+70520653484143
ENST00000254321ZNF700chr1912036088+ENST00000316856RAD23Achr1913063502+1059206845402147
ENST00000254321ZNF700chr1912036088+ENST00000586534RAD23Achr1913063502+1078206845402147
ENST00000254321ZNF700chr1912036087+ENST00000541222RAD23Achr1913063502+70520653484143
ENST00000254321ZNF700chr1912036087+ENST00000316856RAD23Achr1913063502+1059206845402147
ENST00000254321ZNF700chr1912036087+ENST00000586534RAD23Achr1913063502+1078206845402147

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000254321ENST00000541222ZNF700chr1912036088+RAD23Achr1913063503+0.0296396450.97036034
ENST00000254321ENST00000316856ZNF700chr1912036088+RAD23Achr1913063503+0.65103850.34896144
ENST00000254321ENST00000586534ZNF700chr1912036088+RAD23Achr1913063503+0.69676650.30323353
ENST00000254321ENST00000541222ZNF700chr1912036088+RAD23Achr1913063502+0.0296396450.97036034
ENST00000254321ENST00000316856ZNF700chr1912036088+RAD23Achr1913063502+0.65103850.34896144
ENST00000254321ENST00000586534ZNF700chr1912036088+RAD23Achr1913063502+0.69676650.30323353
ENST00000254321ENST00000541222ZNF700chr1912036087+RAD23Achr1913063502+0.0296396450.97036034
ENST00000254321ENST00000316856ZNF700chr1912036087+RAD23Achr1913063502+0.65103850.34896144
ENST00000254321ENST00000586534ZNF700chr1912036087+RAD23Achr1913063502+0.69676650.30323353

Top

Fusion Genomic Features for ZNF700-RAD23A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNF700chr1912036088+RAD23Achr1913063502+1.04E-151
ZNF700chr1912036088+RAD23Achr1913063502+1.04E-151
ZNF700chr1912036088+RAD23Achr1913063502+1.04E-151
ZNF700chr1912036088+RAD23Achr1913063502+1.04E-151

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for ZNF700-RAD23A


check button Go to

FGviewer for the breakpoints of chr19:12036088-chr19:13063503

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRAD23Achr19:12036087chr19:13063502ENST0000058653469318_358271.0364.0DomainUBA 2
TgeneRAD23Achr19:12036087chr19:13063502ENST0000059226808161_2010309.0DomainUBA 1
TgeneRAD23Achr19:12036087chr19:13063502ENST00000592268081_810309.0DomainUbiquitin-like
TgeneRAD23Achr19:12036087chr19:13063502ENST0000059226808318_3580309.0DomainUBA 2
TgeneRAD23Achr19:12036088chr19:13063502ENST0000058653469318_358271.0364.0DomainUBA 2
TgeneRAD23Achr19:12036088chr19:13063502ENST0000059226808161_2010309.0DomainUBA 1
TgeneRAD23Achr19:12036088chr19:13063502ENST00000592268081_810309.0DomainUbiquitin-like
TgeneRAD23Achr19:12036088chr19:13063502ENST0000059226808318_3580309.0DomainUBA 2
TgeneRAD23Achr19:12036088chr19:13063503ENST0000058653469318_358271.0364.0DomainUBA 2
TgeneRAD23Achr19:12036088chr19:13063503ENST0000059226808161_2010309.0DomainUBA 1
TgeneRAD23Achr19:12036088chr19:13063503ENST00000592268081_810309.0DomainUbiquitin-like
TgeneRAD23Achr19:12036088chr19:13063503ENST0000059226808318_3580309.0DomainUBA 2
TgeneRAD23Achr19:12036087chr19:13063502ENST0000058653469319_363271.0364.0RegionNote=HIV-1 vpr binding
TgeneRAD23Achr19:12036087chr19:13063502ENST0000059226808319_3630309.0RegionNote=HIV-1 vpr binding
TgeneRAD23Achr19:12036088chr19:13063502ENST0000058653469319_363271.0364.0RegionNote=HIV-1 vpr binding
TgeneRAD23Achr19:12036088chr19:13063502ENST0000059226808319_3630309.0RegionNote=HIV-1 vpr binding
TgeneRAD23Achr19:12036088chr19:13063503ENST0000058653469319_363271.0364.0RegionNote=HIV-1 vpr binding
TgeneRAD23Achr19:12036088chr19:13063503ENST0000059226808319_3630309.0RegionNote=HIV-1 vpr binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+1424_10421.0743.0DomainKRAB
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+1424_10421.0743.0DomainKRAB
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+1424_10421.0743.0DomainKRAB
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14194_21621.0743.0Zinc fingerC2H2-type 1
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14222_24421.0743.0Zinc fingerC2H2-type 2
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14250_27221.0743.0Zinc fingerC2H2-type 3
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14278_30021.0743.0Zinc fingerC2H2-type 4
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14306_32821.0743.0Zinc fingerC2H2-type 5
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14362_38421.0743.0Zinc fingerC2H2-type 6
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14390_41221.0743.0Zinc fingerC2H2-type 7
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14418_44021.0743.0Zinc fingerC2H2-type 8
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14446_46821.0743.0Zinc fingerC2H2-type 9
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14474_50221.0743.0Zinc fingerC2H2-type 10%3B degenerate
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14508_53021.0743.0Zinc fingerC2H2-type 11
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14536_55821.0743.0Zinc fingerC2H2-type 12
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14564_58621.0743.0Zinc fingerC2H2-type 13
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14592_61421.0743.0Zinc fingerC2H2-type 14
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14620_64221.0743.0Zinc fingerC2H2-type 15
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14648_67021.0743.0Zinc fingerC2H2-type 16
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14676_69821.0743.0Zinc fingerC2H2-type 17
HgeneZNF700chr19:12036087chr19:13063502ENST00000254321+14704_72621.0743.0Zinc fingerC2H2-type 18
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14194_21621.0743.0Zinc fingerC2H2-type 1
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14222_24421.0743.0Zinc fingerC2H2-type 2
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14250_27221.0743.0Zinc fingerC2H2-type 3
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14278_30021.0743.0Zinc fingerC2H2-type 4
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14306_32821.0743.0Zinc fingerC2H2-type 5
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14362_38421.0743.0Zinc fingerC2H2-type 6
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14390_41221.0743.0Zinc fingerC2H2-type 7
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14418_44021.0743.0Zinc fingerC2H2-type 8
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14446_46821.0743.0Zinc fingerC2H2-type 9
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14474_50221.0743.0Zinc fingerC2H2-type 10%3B degenerate
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14508_53021.0743.0Zinc fingerC2H2-type 11
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14536_55821.0743.0Zinc fingerC2H2-type 12
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14564_58621.0743.0Zinc fingerC2H2-type 13
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14592_61421.0743.0Zinc fingerC2H2-type 14
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14620_64221.0743.0Zinc fingerC2H2-type 15
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14648_67021.0743.0Zinc fingerC2H2-type 16
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14676_69821.0743.0Zinc fingerC2H2-type 17
HgeneZNF700chr19:12036088chr19:13063502ENST00000254321+14704_72621.0743.0Zinc fingerC2H2-type 18
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14194_21621.0743.0Zinc fingerC2H2-type 1
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14222_24421.0743.0Zinc fingerC2H2-type 2
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14250_27221.0743.0Zinc fingerC2H2-type 3
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14278_30021.0743.0Zinc fingerC2H2-type 4
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14306_32821.0743.0Zinc fingerC2H2-type 5
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14362_38421.0743.0Zinc fingerC2H2-type 6
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14390_41221.0743.0Zinc fingerC2H2-type 7
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14418_44021.0743.0Zinc fingerC2H2-type 8
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14446_46821.0743.0Zinc fingerC2H2-type 9
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14474_50221.0743.0Zinc fingerC2H2-type 10%3B degenerate
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14508_53021.0743.0Zinc fingerC2H2-type 11
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14536_55821.0743.0Zinc fingerC2H2-type 12
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14564_58621.0743.0Zinc fingerC2H2-type 13
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14592_61421.0743.0Zinc fingerC2H2-type 14
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14620_64221.0743.0Zinc fingerC2H2-type 15
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14648_67021.0743.0Zinc fingerC2H2-type 16
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14676_69821.0743.0Zinc fingerC2H2-type 17
HgeneZNF700chr19:12036088chr19:13063503ENST00000254321+14704_72621.0743.0Zinc fingerC2H2-type 18
TgeneRAD23Achr19:12036087chr19:13063502ENST0000058653469161_201271.0364.0DomainUBA 1
TgeneRAD23Achr19:12036087chr19:13063502ENST00000586534691_81271.0364.0DomainUbiquitin-like
TgeneRAD23Achr19:12036088chr19:13063502ENST0000058653469161_201271.0364.0DomainUBA 1
TgeneRAD23Achr19:12036088chr19:13063502ENST00000586534691_81271.0364.0DomainUbiquitin-like
TgeneRAD23Achr19:12036088chr19:13063503ENST0000058653469161_201271.0364.0DomainUBA 1
TgeneRAD23Achr19:12036088chr19:13063503ENST00000586534691_81271.0364.0DomainUbiquitin-like


Top

Fusion Gene Sequence for ZNF700-RAD23A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000254321_ENST00000541222_TCGA-HS-A5N9-01A_ZNF700_chr19_12036088_+_RAD23A_chr19_13063503_length(transcript)=705nt_BP=206nt
ACTGCCCACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCC
CGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACC
CCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGG
ACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAG
CTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCA
ACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTT
TATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGC

>In-frame_ENST00000254321_ENST00000541222_TCGA-HS-A5N9-01A_ZNF700_chr19_12036088_+_RAD23A_chr19_13063503_length(amino acids)=143AA_start in transcript=53_stop in transcript=484
MRGRRLVTGQTSPRGTWCLYPGFCRSVACAMPCCSHRSCREDPGTSESREMQISRHQEQFIQMLNEPPGELADISDVEGEVGAIGEEAPQ

--------------------------------------------------------------
>In-frame_ENST00000254321_ENST00000316856_TCGA-HS-A5N9-01A_ZNF700_chr19_12036088_+_RAD23A_chr19_13063503_length(transcript)=1059nt_BP=206nt
ACTGCCCACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCC
CGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACC
CCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGG
ACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAG
CTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCA
ACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTT
TATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGC
TTCCTGTCCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCCAGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGA
AGCTGGCAGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCTCTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCT
CCATCCTCCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTCTAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGT
GGCCCAAATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAGGCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAA

>In-frame_ENST00000254321_ENST00000316856_TCGA-HS-A5N9-01A_ZNF700_chr19_12036088_+_RAD23A_chr19_13063503_length(amino acids)=147AA_start in transcript=845_stop in transcript=402
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------
>In-frame_ENST00000254321_ENST00000586534_TCGA-HS-A5N9-01A_ZNF700_chr19_12036088_+_RAD23A_chr19_13063503_length(transcript)=1078nt_BP=206nt
ACTGCCCACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCC
CGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACC
CCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGG
ACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAG
CTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCA
ACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTT
TATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGC
TTCCTGTCCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCCAGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGA
AGCTGGCAGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCTCTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCT
CCATCCTCCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTCTAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGT
GGCCCAAATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAGGCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAA

>In-frame_ENST00000254321_ENST00000586534_TCGA-HS-A5N9-01A_ZNF700_chr19_12036088_+_RAD23A_chr19_13063503_length(amino acids)=147AA_start in transcript=845_stop in transcript=402
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------
>In-frame_ENST00000254321_ENST00000541222_TCGA-HS-A5N9_ZNF700_chr19_12036088_+_RAD23A_chr19_13063502_length(transcript)=705nt_BP=206nt
ACTGCCCACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCC
CGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACC
CCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGG
ACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAG
CTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCA
ACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTT
TATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGC

>In-frame_ENST00000254321_ENST00000541222_TCGA-HS-A5N9_ZNF700_chr19_12036088_+_RAD23A_chr19_13063502_length(amino acids)=143AA_start in transcript=53_stop in transcript=484
MRGRRLVTGQTSPRGTWCLYPGFCRSVACAMPCCSHRSCREDPGTSESREMQISRHQEQFIQMLNEPPGELADISDVEGEVGAIGEEAPQ

--------------------------------------------------------------
>In-frame_ENST00000254321_ENST00000316856_TCGA-HS-A5N9_ZNF700_chr19_12036088_+_RAD23A_chr19_13063502_length(transcript)=1059nt_BP=206nt
ACTGCCCACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCC
CGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACC
CCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGG
ACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAG
CTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCA
ACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTT
TATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGC
TTCCTGTCCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCCAGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGA
AGCTGGCAGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCTCTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCT
CCATCCTCCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTCTAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGT
GGCCCAAATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAGGCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAA

>In-frame_ENST00000254321_ENST00000316856_TCGA-HS-A5N9_ZNF700_chr19_12036088_+_RAD23A_chr19_13063502_length(amino acids)=147AA_start in transcript=845_stop in transcript=402
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------
>In-frame_ENST00000254321_ENST00000586534_TCGA-HS-A5N9_ZNF700_chr19_12036088_+_RAD23A_chr19_13063502_length(transcript)=1078nt_BP=206nt
ACTGCCCACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCC
CGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACC
CCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGG
ACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAG
CTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCA
ACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTT
TATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGC
TTCCTGTCCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCCAGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGA
AGCTGGCAGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCTCTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCT
CCATCCTCCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTCTAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGT
GGCCCAAATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAGGCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAA

>In-frame_ENST00000254321_ENST00000586534_TCGA-HS-A5N9_ZNF700_chr19_12036088_+_RAD23A_chr19_13063502_length(amino acids)=147AA_start in transcript=845_stop in transcript=402
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------
>In-frame_ENST00000254321_ENST00000541222_TCGA-HS-A5N9-01A_ZNF700_chr19_12036087_+_RAD23A_chr19_13063502_length(transcript)=705nt_BP=206nt
ACTGCCCACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCC
CGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACC
CCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGG
ACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAG
CTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCA
ACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTT
TATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGC

>In-frame_ENST00000254321_ENST00000541222_TCGA-HS-A5N9-01A_ZNF700_chr19_12036087_+_RAD23A_chr19_13063502_length(amino acids)=143AA_start in transcript=53_stop in transcript=484
MRGRRLVTGQTSPRGTWCLYPGFCRSVACAMPCCSHRSCREDPGTSESREMQISRHQEQFIQMLNEPPGELADISDVEGEVGAIGEEAPQ

--------------------------------------------------------------
>In-frame_ENST00000254321_ENST00000316856_TCGA-HS-A5N9-01A_ZNF700_chr19_12036087_+_RAD23A_chr19_13063502_length(transcript)=1059nt_BP=206nt
ACTGCCCACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCC
CGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACC
CCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGG
ACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAG
CTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCA
ACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTT
TATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGC
TTCCTGTCCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCCAGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGA
AGCTGGCAGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCTCTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCT
CCATCCTCCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTCTAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGT
GGCCCAAATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAGGCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAA

>In-frame_ENST00000254321_ENST00000316856_TCGA-HS-A5N9-01A_ZNF700_chr19_12036087_+_RAD23A_chr19_13063502_length(amino acids)=147AA_start in transcript=845_stop in transcript=402
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------
>In-frame_ENST00000254321_ENST00000586534_TCGA-HS-A5N9-01A_ZNF700_chr19_12036087_+_RAD23A_chr19_13063502_length(transcript)=1078nt_BP=206nt
ACTGCCCACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCC
CGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACC
CCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGG
ACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAG
CTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCA
ACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTT
TATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGC
TTCCTGTCCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCCAGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGA
AGCTGGCAGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCTCTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCT
CCATCCTCCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTCTAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGT
GGCCCAAATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAGGCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAA

>In-frame_ENST00000254321_ENST00000586534_TCGA-HS-A5N9-01A_ZNF700_chr19_12036087_+_RAD23A_chr19_13063502_length(amino acids)=147AA_start in transcript=845_stop in transcript=402
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ZNF700-RAD23A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for ZNF700-RAD23A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for ZNF700-RAD23A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneRAD23AC0024623Malignant neoplasm of stomach1CTD_human
TgeneRAD23AC0038356Stomach Neoplasms1CTD_human
TgeneRAD23AC0235874Disease Exacerbation1CTD_human
TgeneRAD23AC1708349Hereditary Diffuse Gastric Cancer1CTD_human