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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CAAP1-TNNI3K (FusionGDB2 ID:12255)

Fusion Gene Summary for CAAP1-TNNI3K

check button Fusion gene summary
Fusion gene informationFusion gene name: CAAP1-TNNI3K
Fusion gene ID: 12255
HgeneTgene
Gene symbol

CAAP1

TNNI3K

Gene ID

79886

100526835

Gene namecaspase activity and apoptosis inhibitor 1FPGT-TNNI3K readthrough
SynonymsC9orf82|CAAPCARK|TNNI3K
Cytomap

9p21.2

1p31.1

Type of geneprotein-codingprotein-coding
Descriptioncaspase activity and apoptosis inhibitor 1conserved anti-apoptotic proteinFPGT-TNNI3K fusion proteinCardiac ankyrin repeat kinaseCardiac troponin I-interacting kinaseSerine/threonine-protein kinase TNNI3KTNNI3-interacting kinase
Modification date2020031320200313
UniProtAcc

Q9H8G2

.
Ensembl transtripts involved in fusion geneENST00000333916, ENST00000535437, 
ENST00000520187, ENST00000495958, 
ENST00000370891, ENST00000326637, 
ENST00000465473, 
Fusion gene scores* DoF score5 X 4 X 5=1005 X 5 X 4=100
# samples 66
** MAII scorelog2(6/100*10)=-0.736965594166206
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/100*10)=-0.736965594166206
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CAAP1 [Title/Abstract] AND TNNI3K [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCAAP1(26861064)-TNNI3K(74832940), # samples:2
Anticipated loss of major functional domain due to fusion event.CAAP1-TNNI3K seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
CAAP1-TNNI3K seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CAAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across TNNI3K (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-61-2095-01ACAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
ChimerDB4OVTCGA-61-2095CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
ChimerDB4OVTCGA-61-2095-01ACAAP1chr9

26861064

-TNNI3Kchr1

74832940

+


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Fusion Gene ORF analysis for CAAP1-TNNI3K

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000333916ENST00000370891CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
In-frameENST00000333916ENST00000326637CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
5CDS-intronENST00000333916ENST00000465473CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
Frame-shiftENST00000535437ENST00000370891CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
Frame-shiftENST00000535437ENST00000326637CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
5CDS-intronENST00000535437ENST00000465473CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-3CDSENST00000520187ENST00000370891CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-3CDSENST00000520187ENST00000326637CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-intronENST00000520187ENST00000465473CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-3CDSENST00000495958ENST00000370891CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-3CDSENST00000495958ENST00000326637CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-intronENST00000495958ENST00000465473CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
In-frameENST00000333916ENST00000370891CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
In-frameENST00000333916ENST00000326637CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
5CDS-intronENST00000333916ENST00000465473CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
Frame-shiftENST00000535437ENST00000370891CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
Frame-shiftENST00000535437ENST00000326637CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
5CDS-intronENST00000535437ENST00000465473CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-3CDSENST00000520187ENST00000370891CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-3CDSENST00000520187ENST00000326637CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-intronENST00000520187ENST00000465473CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-3CDSENST00000495958ENST00000370891CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-3CDSENST00000495958ENST00000326637CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-intronENST00000495958ENST00000465473CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000333916CAAP1chr926861064-ENST00000370891TNNI3Kchr174832940+2601828892158689
ENST00000333916CAAP1chr926861064-ENST00000326637TNNI3Kchr174832940+2601828892158689
ENST00000333916CAAP1chr926861063-ENST00000370891TNNI3Kchr174832939+2601828892158689
ENST00000333916CAAP1chr926861063-ENST00000326637TNNI3Kchr174832939+2601828892158689

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000333916ENST00000370891CAAP1chr926861064-TNNI3Kchr174832940+0.0043653910.9956346
ENST00000333916ENST00000326637CAAP1chr926861064-TNNI3Kchr174832940+0.0043653910.9956346
ENST00000333916ENST00000370891CAAP1chr926861063-TNNI3Kchr174832939+0.0043653910.9956346
ENST00000333916ENST00000326637CAAP1chr926861063-TNNI3Kchr174832939+0.0043653910.9956346

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Fusion Genomic Features for CAAP1-TNNI3K


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CAAP1chr926861063-TNNI3Kchr174832939+0.0014876020.9985123
CAAP1chr926861063-TNNI3Kchr174832939+0.0014876020.9985123
CAAP1chr926861063-TNNI3Kchr174832939+0.0014876020.9985123
CAAP1chr926861063-TNNI3Kchr174832939+0.0014876020.9985123

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CAAP1-TNNI3K


check button Go to

FGviewer for the breakpoints of chr9:26861064-chr1:74832940

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CAAP1

Q9H8G2

.
FUNCTION: Anti-apoptotic protein that modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop. {ECO:0000269|PubMed:21980415}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCAAP1chr9:26861063chr1:74832939ENST00000333916-5619_25246.33333333333334362.0Compositional biasNote=Poly-Ala
HgeneCAAP1chr9:26861063chr1:74832939ENST00000535437-5619_25101.33333333333333217.0Compositional biasNote=Poly-Ala
HgeneCAAP1chr9:26861064chr1:74832940ENST00000333916-5619_25246.33333333333334362.0Compositional biasNote=Poly-Ala
HgeneCAAP1chr9:26861064chr1:74832940ENST00000535437-5619_25101.33333333333333217.0Compositional biasNote=Poly-Ala
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025733_746392.3333333333333836.0Compositional biasNote=Poly-Ser
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227733_746493.3333333333333937.0Compositional biasNote=Poly-Ser
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025733_746392.3333333333333836.0Compositional biasNote=Poly-Ser
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227733_746493.3333333333333937.0Compositional biasNote=Poly-Ser
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025463_723392.3333333333333836.0DomainProtein kinase
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025463_723392.3333333333333836.0DomainProtein kinase
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025469_477392.3333333333333836.0Nucleotide bindingATP
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025469_477392.3333333333333836.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCAAP1chr9:26861063chr1:74832939ENST00000333916-56281_311246.33333333333334362.0Coiled coilOntology_term=ECO:0000255
HgeneCAAP1chr9:26861063chr1:74832939ENST00000535437-56281_311101.33333333333333217.0Coiled coilOntology_term=ECO:0000255
HgeneCAAP1chr9:26861064chr1:74832940ENST00000333916-56281_311246.33333333333334362.0Coiled coilOntology_term=ECO:0000255
HgeneCAAP1chr9:26861064chr1:74832940ENST00000535437-56281_311101.33333333333333217.0Coiled coilOntology_term=ECO:0000255
TgeneTNNI3Kchr9:26861063chr1:74832939ENST00000326637102521_51392.3333333333333836.0Coiled coilOntology_term=ECO:0000255
TgeneTNNI3Kchr9:26861063chr1:74832939ENST00000370891122721_51493.3333333333333937.0Coiled coilOntology_term=ECO:0000255
TgeneTNNI3Kchr9:26861064chr1:74832940ENST00000326637102521_51392.3333333333333836.0Coiled coilOntology_term=ECO:0000255
TgeneTNNI3Kchr9:26861064chr1:74832940ENST00000370891122721_51493.3333333333333937.0Coiled coilOntology_term=ECO:0000255
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227463_723493.3333333333333937.0DomainProtein kinase
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227463_723493.3333333333333937.0DomainProtein kinase
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227469_477493.3333333333333937.0Nucleotide bindingATP
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227469_477493.3333333333333937.0Nucleotide bindingATP
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025100_129392.3333333333333836.0RepeatNote=ANK 2
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025133_162392.3333333333333836.0RepeatNote=ANK 3
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025166_195392.3333333333333836.0RepeatNote=ANK 4
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025199_228392.3333333333333836.0RepeatNote=ANK 5
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025234_263392.3333333333333836.0RepeatNote=ANK 6
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025269_298392.3333333333333836.0RepeatNote=ANK 7
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025304_335392.3333333333333836.0RepeatNote=ANK 8
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025339_368392.3333333333333836.0RepeatNote=ANK 9
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025381_410392.3333333333333836.0RepeatNote=ANK 10
TgeneTNNI3Kchr9:26861063chr1:74832939ENST00000326637102566_96392.3333333333333836.0RepeatNote=ANK 1
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227100_129493.3333333333333937.0RepeatNote=ANK 2
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227133_162493.3333333333333937.0RepeatNote=ANK 3
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227166_195493.3333333333333937.0RepeatNote=ANK 4
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227199_228493.3333333333333937.0RepeatNote=ANK 5
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227234_263493.3333333333333937.0RepeatNote=ANK 6
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227269_298493.3333333333333937.0RepeatNote=ANK 7
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227304_335493.3333333333333937.0RepeatNote=ANK 8
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227339_368493.3333333333333937.0RepeatNote=ANK 9
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227381_410493.3333333333333937.0RepeatNote=ANK 10
TgeneTNNI3Kchr9:26861063chr1:74832939ENST00000370891122766_96493.3333333333333937.0RepeatNote=ANK 1
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025100_129392.3333333333333836.0RepeatNote=ANK 2
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025133_162392.3333333333333836.0RepeatNote=ANK 3
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025166_195392.3333333333333836.0RepeatNote=ANK 4
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025199_228392.3333333333333836.0RepeatNote=ANK 5
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025234_263392.3333333333333836.0RepeatNote=ANK 6
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025269_298392.3333333333333836.0RepeatNote=ANK 7
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025304_335392.3333333333333836.0RepeatNote=ANK 8
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025339_368392.3333333333333836.0RepeatNote=ANK 9
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025381_410392.3333333333333836.0RepeatNote=ANK 10
TgeneTNNI3Kchr9:26861064chr1:74832940ENST00000326637102566_96392.3333333333333836.0RepeatNote=ANK 1
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227100_129493.3333333333333937.0RepeatNote=ANK 2
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227133_162493.3333333333333937.0RepeatNote=ANK 3
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227166_195493.3333333333333937.0RepeatNote=ANK 4
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227199_228493.3333333333333937.0RepeatNote=ANK 5
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227234_263493.3333333333333937.0RepeatNote=ANK 6
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227269_298493.3333333333333937.0RepeatNote=ANK 7
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227304_335493.3333333333333937.0RepeatNote=ANK 8
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227339_368493.3333333333333937.0RepeatNote=ANK 9
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227381_410493.3333333333333937.0RepeatNote=ANK 10
TgeneTNNI3Kchr9:26861064chr1:74832940ENST00000370891122766_96493.3333333333333937.0RepeatNote=ANK 1


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Fusion Gene Sequence for CAAP1-TNNI3K


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000333916_ENST00000370891_TCGA-61-2095-01A_CAAP1_chr9_26861064_-_TNNI3K_chr1_74832940_length(transcript)=2601nt_BP=828nt
CCAGTGCCTGCCGCCCACGGCCGCAGGAGTCGGGCTTCGGTCGCACCAGAGACAGCGGACTTTCCTCCGATGGTTGCAGCAGAGGGATCA
TGACGGGGAAAAAGTCCTCCCGGGAGAAACGGCGCAAACGTAGCAGTCAGGAGGCGGCCGCAGCGCTCGCGGCCCCGGACATCGTACCCG
CGTTGGCCAGCGGCAGCAGTGGAAGCACTAGCGGCTGCGGGAGCGCCGGGGGCTGCGGGAGCGTCAGCTGCTGTGGGAACGCCAATTTTA
GTGGAAGTGTCACCGGCGGTGGGAGCGGCGGCAGCTGTTGGGGCGGGAGCAGCGTGGAGCGCAGCGAGCGCCGGAAGCGGAGGAGTACCG
ACTCTTCCAGCGTCTCGGGCTCCTTGCAGCAGGAAACTAAATATATTTTGCCAACTTTGGAAAAAGAATTATTCTTGGCAGAGCACAGTG
ACCTTGAAGAAGGTGGACTGGACCTGACTGTGTCATTGAAACCAGTTAGTTTCTATATATCAGACAAAAAAGAAATGCTTCAGCAGTGCT
TCTGTATTATAGGAGAGAAAAAGTTACAGAAGATGCTTCCTGATGTGTTAAAGAACTGTTCAATAGAAGAAATTAAAAAACTATGCCAGG
AACAGTTAGAGCTCCTGTCTGAAAAAAAAATTTTGAAGATTCTTGAGGGTGACAATGGAATGGACTCTGATATGGAAGAGGAAGCAGATG
ATGGTTCTAAGATGGGATCTGATTTAGTCAGTCAGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAG
GTTTGGAATTAAAACAAGGGCATGATGCCATTGTCACACTCCTGAAGCATTATAAGAGACCACAAGATGAATTGCCCTGTAATGAATATT
CTCAGCCTGGAGGAGATGGCTCCTATGTGTCTGTTCCATCACCCTTGGGGAAGATTAAAAGCATGACAAAAGAGAAGGCAGATATTCTCC
TCCTAAGAGCTGGATTGCCTTCACATTTCCATCTTCAGCTCTCAGAAATTGAGTTCCATGAGATTATTGGCTCAGGTTCTTTTGGGAAAG
TATATAAAGGACGATGCAGAAATAAAATAGTGGCTATAAAACGTTATCGAGCCAATACCTACTGCTCCAAGTCAGATGTGGATATGTTTT
GCCGAGAGGTGTCCATTCTCTGCCAGCTCAATCATCCCTGCGTAATTCAGTTTGTGGGTGCTTGCTTGAATGATCCCAGCCAGTTTGCCA
TTGTCACTCAATACATATCAGGGGGTTCTCTGTTCTCCCTCCTTCATGAGCAGAAGAGGATTCTTGATTTGCAGTCTAAATTAATTATTG
CAGTAGATGTTGCCAAAGGCATGGAGTACCTTCACAACCTGACACAGCCAATTATACATCGTGACTTGAACAGTCACAATATTCTTCTCT
ATGAGGATGGGCATGCTGTGGTGGCAGATTTTGGAGAATCAAGATTTCTACAGTCTCTGGATGAAGACAACATGACAAAACAACCTGGGA
ACCTCCGTTGGATGGCTCCTGAGGTGTTCACGCAGTGCACTCGGTACACCATCAAAGCAGATGTCTTCAGCTATGCTCTGTGTCTGTGGG
AAATTCTCACTGGCGAAATTCCATTCGCTCATCTCAAGCCAGCGGCTGCGGCAGCAGACATGGCTTACCACCACATCAGACCTCCCATTG
GCTATTCCATTCCCAAGCCCATATCATCTCTGCTGATACGAGGGTGGAACGCATGTCCTGAAGGAAGACCCGAATTTTCTGAAGTTGTCA
TGAAGTTAGAAGAGTGTCTCTGCAACATTGAGCTGATGTCTCCTGCATCAAGTAACAGCAGTGGGTCTCTCTCACCTTCTTCTTCTTCTG
ATTGCCTGGTGAACCGGGGAGGACCTGGCCGGAGTCATGTGGCAGCATTAAGAAGTCGTTTCGAATTGGAATATGCTCTAAATGCAAGGT
CCTATGCTGCTTTGTCCCAAAGTGCTGGACAATATTCCTCTCAAGGTCTGTCTTTGGAGGAGATGAAAAGAAGTCTTCAATACACACCCA
TTGACAAATATGGCTATGTATCCGATCCCATGAGCTCAATGCATTTTCATTCTTGCCGAAATAGTAGCAGCTTTGAGGACAGCAGCTGAC
AGCATTCGGCGTATACCTAAGGAGAGTTTTTTCCCCGAACTGACAGCAACGATTCCAACCACGGCAAGCTGGCTTCCAACTATAACATTT
TACTCTCAAAGGTCTCCTTAAATTGGGCTTGTTTTTACTTGTCCTATTTAATTCCCCACTATTAGCAGGCTTTGGATTTGTGCCTAAGGA
ATAATATGCAAAAGAACCAAGACAGAATGTATATGAAGAATTGTTTTTAATTTTGTAAATTAAAAAAAAATTTAGATCGTTACTTGGAAA
TGGAGCCTAAGTCTGTGGTGGACAGATAATAATTATGTTTTCCTGGGCTGAATTATGTAGACTTGTGTTTGACAGCTATGGGTTTATTTC

>In-frame_ENST00000333916_ENST00000370891_TCGA-61-2095-01A_CAAP1_chr9_26861064_-_TNNI3K_chr1_74832940_length(amino acids)=689AA_start in transcript=89_stop in transcript=2158
MTGKKSSREKRRKRSSQEAAAALAAPDIVPALASGSSGSTSGCGSAGGCGSVSCCGNANFSGSVTGGGSGGSCWGGSSVERSERRKRRST
DSSSVSGSLQQETKYILPTLEKELFLAEHSDLEEGGLDLTVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQ
EQLELLSEKKILKILEGDNGMDSDMEEEADDGSKMGSDLVSQQDICIDSASSVRENKQPEGLELKQGHDAIVTLLKHYKRPQDELPCNEY
SQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMF
CREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILL
YEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPI
GYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR

--------------------------------------------------------------
>In-frame_ENST00000333916_ENST00000326637_TCGA-61-2095-01A_CAAP1_chr9_26861064_-_TNNI3K_chr1_74832940_length(transcript)=2601nt_BP=828nt
CCAGTGCCTGCCGCCCACGGCCGCAGGAGTCGGGCTTCGGTCGCACCAGAGACAGCGGACTTTCCTCCGATGGTTGCAGCAGAGGGATCA
TGACGGGGAAAAAGTCCTCCCGGGAGAAACGGCGCAAACGTAGCAGTCAGGAGGCGGCCGCAGCGCTCGCGGCCCCGGACATCGTACCCG
CGTTGGCCAGCGGCAGCAGTGGAAGCACTAGCGGCTGCGGGAGCGCCGGGGGCTGCGGGAGCGTCAGCTGCTGTGGGAACGCCAATTTTA
GTGGAAGTGTCACCGGCGGTGGGAGCGGCGGCAGCTGTTGGGGCGGGAGCAGCGTGGAGCGCAGCGAGCGCCGGAAGCGGAGGAGTACCG
ACTCTTCCAGCGTCTCGGGCTCCTTGCAGCAGGAAACTAAATATATTTTGCCAACTTTGGAAAAAGAATTATTCTTGGCAGAGCACAGTG
ACCTTGAAGAAGGTGGACTGGACCTGACTGTGTCATTGAAACCAGTTAGTTTCTATATATCAGACAAAAAAGAAATGCTTCAGCAGTGCT
TCTGTATTATAGGAGAGAAAAAGTTACAGAAGATGCTTCCTGATGTGTTAAAGAACTGTTCAATAGAAGAAATTAAAAAACTATGCCAGG
AACAGTTAGAGCTCCTGTCTGAAAAAAAAATTTTGAAGATTCTTGAGGGTGACAATGGAATGGACTCTGATATGGAAGAGGAAGCAGATG
ATGGTTCTAAGATGGGATCTGATTTAGTCAGTCAGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAG
GTTTGGAATTAAAACAAGGGCATGATGCCATTGTCACACTCCTGAAGCATTATAAGAGACCACAAGATGAATTGCCCTGTAATGAATATT
CTCAGCCTGGAGGAGATGGCTCCTATGTGTCTGTTCCATCACCCTTGGGGAAGATTAAAAGCATGACAAAAGAGAAGGCAGATATTCTCC
TCCTAAGAGCTGGATTGCCTTCACATTTCCATCTTCAGCTCTCAGAAATTGAGTTCCATGAGATTATTGGCTCAGGTTCTTTTGGGAAAG
TATATAAAGGACGATGCAGAAATAAAATAGTGGCTATAAAACGTTATCGAGCCAATACCTACTGCTCCAAGTCAGATGTGGATATGTTTT
GCCGAGAGGTGTCCATTCTCTGCCAGCTCAATCATCCCTGCGTAATTCAGTTTGTGGGTGCTTGCTTGAATGATCCCAGCCAGTTTGCCA
TTGTCACTCAATACATATCAGGGGGTTCTCTGTTCTCCCTCCTTCATGAGCAGAAGAGGATTCTTGATTTGCAGTCTAAATTAATTATTG
CAGTAGATGTTGCCAAAGGCATGGAGTACCTTCACAACCTGACACAGCCAATTATACATCGTGACTTGAACAGTCACAATATTCTTCTCT
ATGAGGATGGGCATGCTGTGGTGGCAGATTTTGGAGAATCAAGATTTCTACAGTCTCTGGATGAAGACAACATGACAAAACAACCTGGGA
ACCTCCGTTGGATGGCTCCTGAGGTGTTCACGCAGTGCACTCGGTACACCATCAAAGCAGATGTCTTCAGCTATGCTCTGTGTCTGTGGG
AAATTCTCACTGGCGAAATTCCATTCGCTCATCTCAAGCCAGCGGCTGCGGCAGCAGACATGGCTTACCACCACATCAGACCTCCCATTG
GCTATTCCATTCCCAAGCCCATATCATCTCTGCTGATACGAGGGTGGAACGCATGTCCTGAAGGAAGACCCGAATTTTCTGAAGTTGTCA
TGAAGTTAGAAGAGTGTCTCTGCAACATTGAGCTGATGTCTCCTGCATCAAGTAACAGCAGTGGGTCTCTCTCACCTTCTTCTTCTTCTG
ATTGCCTGGTGAACCGGGGAGGACCTGGCCGGAGTCATGTGGCAGCATTAAGAAGTCGTTTCGAATTGGAATATGCTCTAAATGCAAGGT
CCTATGCTGCTTTGTCCCAAAGTGCTGGACAATATTCCTCTCAAGGTCTGTCTTTGGAGGAGATGAAAAGAAGTCTTCAATACACACCCA
TTGACAAATATGGCTATGTATCCGATCCCATGAGCTCAATGCATTTTCATTCTTGCCGAAATAGTAGCAGCTTTGAGGACAGCAGCTGAC
AGCATTCGGCGTATACCTAAGGAGAGTTTTTTCCCCGAACTGACAGCAACGATTCCAACCACGGCAAGCTGGCTTCCAACTATAACATTT
TACTCTCAAAGGTCTCCTTAAATTGGGCTTGTTTTTACTTGTCCTATTTAATTCCCCACTATTAGCAGGCTTTGGATTTGTGCCTAAGGA
ATAATATGCAAAAGAACCAAGACAGAATGTATATGAAGAATTGTTTTTAATTTTGTAAATTAAAAAAAAATTTAGATCGTTACTTGGAAA
TGGAGCCTAAGTCTGTGGTGGACAGATAATAATTATGTTTTCCTGGGCTGAATTATGTAGACTTGTGTTTGACAGCTATGGGTTTATTTC

>In-frame_ENST00000333916_ENST00000326637_TCGA-61-2095-01A_CAAP1_chr9_26861064_-_TNNI3K_chr1_74832940_length(amino acids)=689AA_start in transcript=89_stop in transcript=2158
MTGKKSSREKRRKRSSQEAAAALAAPDIVPALASGSSGSTSGCGSAGGCGSVSCCGNANFSGSVTGGGSGGSCWGGSSVERSERRKRRST
DSSSVSGSLQQETKYILPTLEKELFLAEHSDLEEGGLDLTVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQ
EQLELLSEKKILKILEGDNGMDSDMEEEADDGSKMGSDLVSQQDICIDSASSVRENKQPEGLELKQGHDAIVTLLKHYKRPQDELPCNEY
SQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMF
CREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILL
YEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPI
GYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR

--------------------------------------------------------------
>In-frame_ENST00000333916_ENST00000370891_TCGA-61-2095_CAAP1_chr9_26861063_-_TNNI3K_chr1_74832939_length(transcript)=2601nt_BP=828nt
CCAGTGCCTGCCGCCCACGGCCGCAGGAGTCGGGCTTCGGTCGCACCAGAGACAGCGGACTTTCCTCCGATGGTTGCAGCAGAGGGATCA
TGACGGGGAAAAAGTCCTCCCGGGAGAAACGGCGCAAACGTAGCAGTCAGGAGGCGGCCGCAGCGCTCGCGGCCCCGGACATCGTACCCG
CGTTGGCCAGCGGCAGCAGTGGAAGCACTAGCGGCTGCGGGAGCGCCGGGGGCTGCGGGAGCGTCAGCTGCTGTGGGAACGCCAATTTTA
GTGGAAGTGTCACCGGCGGTGGGAGCGGCGGCAGCTGTTGGGGCGGGAGCAGCGTGGAGCGCAGCGAGCGCCGGAAGCGGAGGAGTACCG
ACTCTTCCAGCGTCTCGGGCTCCTTGCAGCAGGAAACTAAATATATTTTGCCAACTTTGGAAAAAGAATTATTCTTGGCAGAGCACAGTG
ACCTTGAAGAAGGTGGACTGGACCTGACTGTGTCATTGAAACCAGTTAGTTTCTATATATCAGACAAAAAAGAAATGCTTCAGCAGTGCT
TCTGTATTATAGGAGAGAAAAAGTTACAGAAGATGCTTCCTGATGTGTTAAAGAACTGTTCAATAGAAGAAATTAAAAAACTATGCCAGG
AACAGTTAGAGCTCCTGTCTGAAAAAAAAATTTTGAAGATTCTTGAGGGTGACAATGGAATGGACTCTGATATGGAAGAGGAAGCAGATG
ATGGTTCTAAGATGGGATCTGATTTAGTCAGTCAGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAG
GTTTGGAATTAAAACAAGGGCATGATGCCATTGTCACACTCCTGAAGCATTATAAGAGACCACAAGATGAATTGCCCTGTAATGAATATT
CTCAGCCTGGAGGAGATGGCTCCTATGTGTCTGTTCCATCACCCTTGGGGAAGATTAAAAGCATGACAAAAGAGAAGGCAGATATTCTCC
TCCTAAGAGCTGGATTGCCTTCACATTTCCATCTTCAGCTCTCAGAAATTGAGTTCCATGAGATTATTGGCTCAGGTTCTTTTGGGAAAG
TATATAAAGGACGATGCAGAAATAAAATAGTGGCTATAAAACGTTATCGAGCCAATACCTACTGCTCCAAGTCAGATGTGGATATGTTTT
GCCGAGAGGTGTCCATTCTCTGCCAGCTCAATCATCCCTGCGTAATTCAGTTTGTGGGTGCTTGCTTGAATGATCCCAGCCAGTTTGCCA
TTGTCACTCAATACATATCAGGGGGTTCTCTGTTCTCCCTCCTTCATGAGCAGAAGAGGATTCTTGATTTGCAGTCTAAATTAATTATTG
CAGTAGATGTTGCCAAAGGCATGGAGTACCTTCACAACCTGACACAGCCAATTATACATCGTGACTTGAACAGTCACAATATTCTTCTCT
ATGAGGATGGGCATGCTGTGGTGGCAGATTTTGGAGAATCAAGATTTCTACAGTCTCTGGATGAAGACAACATGACAAAACAACCTGGGA
ACCTCCGTTGGATGGCTCCTGAGGTGTTCACGCAGTGCACTCGGTACACCATCAAAGCAGATGTCTTCAGCTATGCTCTGTGTCTGTGGG
AAATTCTCACTGGCGAAATTCCATTCGCTCATCTCAAGCCAGCGGCTGCGGCAGCAGACATGGCTTACCACCACATCAGACCTCCCATTG
GCTATTCCATTCCCAAGCCCATATCATCTCTGCTGATACGAGGGTGGAACGCATGTCCTGAAGGAAGACCCGAATTTTCTGAAGTTGTCA
TGAAGTTAGAAGAGTGTCTCTGCAACATTGAGCTGATGTCTCCTGCATCAAGTAACAGCAGTGGGTCTCTCTCACCTTCTTCTTCTTCTG
ATTGCCTGGTGAACCGGGGAGGACCTGGCCGGAGTCATGTGGCAGCATTAAGAAGTCGTTTCGAATTGGAATATGCTCTAAATGCAAGGT
CCTATGCTGCTTTGTCCCAAAGTGCTGGACAATATTCCTCTCAAGGTCTGTCTTTGGAGGAGATGAAAAGAAGTCTTCAATACACACCCA
TTGACAAATATGGCTATGTATCCGATCCCATGAGCTCAATGCATTTTCATTCTTGCCGAAATAGTAGCAGCTTTGAGGACAGCAGCTGAC
AGCATTCGGCGTATACCTAAGGAGAGTTTTTTCCCCGAACTGACAGCAACGATTCCAACCACGGCAAGCTGGCTTCCAACTATAACATTT
TACTCTCAAAGGTCTCCTTAAATTGGGCTTGTTTTTACTTGTCCTATTTAATTCCCCACTATTAGCAGGCTTTGGATTTGTGCCTAAGGA
ATAATATGCAAAAGAACCAAGACAGAATGTATATGAAGAATTGTTTTTAATTTTGTAAATTAAAAAAAAATTTAGATCGTTACTTGGAAA
TGGAGCCTAAGTCTGTGGTGGACAGATAATAATTATGTTTTCCTGGGCTGAATTATGTAGACTTGTGTTTGACAGCTATGGGTTTATTTC

>In-frame_ENST00000333916_ENST00000370891_TCGA-61-2095_CAAP1_chr9_26861063_-_TNNI3K_chr1_74832939_length(amino acids)=689AA_start in transcript=89_stop in transcript=2158
MTGKKSSREKRRKRSSQEAAAALAAPDIVPALASGSSGSTSGCGSAGGCGSVSCCGNANFSGSVTGGGSGGSCWGGSSVERSERRKRRST
DSSSVSGSLQQETKYILPTLEKELFLAEHSDLEEGGLDLTVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQ
EQLELLSEKKILKILEGDNGMDSDMEEEADDGSKMGSDLVSQQDICIDSASSVRENKQPEGLELKQGHDAIVTLLKHYKRPQDELPCNEY
SQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMF
CREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILL
YEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPI
GYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR

--------------------------------------------------------------
>In-frame_ENST00000333916_ENST00000326637_TCGA-61-2095_CAAP1_chr9_26861063_-_TNNI3K_chr1_74832939_length(transcript)=2601nt_BP=828nt
CCAGTGCCTGCCGCCCACGGCCGCAGGAGTCGGGCTTCGGTCGCACCAGAGACAGCGGACTTTCCTCCGATGGTTGCAGCAGAGGGATCA
TGACGGGGAAAAAGTCCTCCCGGGAGAAACGGCGCAAACGTAGCAGTCAGGAGGCGGCCGCAGCGCTCGCGGCCCCGGACATCGTACCCG
CGTTGGCCAGCGGCAGCAGTGGAAGCACTAGCGGCTGCGGGAGCGCCGGGGGCTGCGGGAGCGTCAGCTGCTGTGGGAACGCCAATTTTA
GTGGAAGTGTCACCGGCGGTGGGAGCGGCGGCAGCTGTTGGGGCGGGAGCAGCGTGGAGCGCAGCGAGCGCCGGAAGCGGAGGAGTACCG
ACTCTTCCAGCGTCTCGGGCTCCTTGCAGCAGGAAACTAAATATATTTTGCCAACTTTGGAAAAAGAATTATTCTTGGCAGAGCACAGTG
ACCTTGAAGAAGGTGGACTGGACCTGACTGTGTCATTGAAACCAGTTAGTTTCTATATATCAGACAAAAAAGAAATGCTTCAGCAGTGCT
TCTGTATTATAGGAGAGAAAAAGTTACAGAAGATGCTTCCTGATGTGTTAAAGAACTGTTCAATAGAAGAAATTAAAAAACTATGCCAGG
AACAGTTAGAGCTCCTGTCTGAAAAAAAAATTTTGAAGATTCTTGAGGGTGACAATGGAATGGACTCTGATATGGAAGAGGAAGCAGATG
ATGGTTCTAAGATGGGATCTGATTTAGTCAGTCAGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAG
GTTTGGAATTAAAACAAGGGCATGATGCCATTGTCACACTCCTGAAGCATTATAAGAGACCACAAGATGAATTGCCCTGTAATGAATATT
CTCAGCCTGGAGGAGATGGCTCCTATGTGTCTGTTCCATCACCCTTGGGGAAGATTAAAAGCATGACAAAAGAGAAGGCAGATATTCTCC
TCCTAAGAGCTGGATTGCCTTCACATTTCCATCTTCAGCTCTCAGAAATTGAGTTCCATGAGATTATTGGCTCAGGTTCTTTTGGGAAAG
TATATAAAGGACGATGCAGAAATAAAATAGTGGCTATAAAACGTTATCGAGCCAATACCTACTGCTCCAAGTCAGATGTGGATATGTTTT
GCCGAGAGGTGTCCATTCTCTGCCAGCTCAATCATCCCTGCGTAATTCAGTTTGTGGGTGCTTGCTTGAATGATCCCAGCCAGTTTGCCA
TTGTCACTCAATACATATCAGGGGGTTCTCTGTTCTCCCTCCTTCATGAGCAGAAGAGGATTCTTGATTTGCAGTCTAAATTAATTATTG
CAGTAGATGTTGCCAAAGGCATGGAGTACCTTCACAACCTGACACAGCCAATTATACATCGTGACTTGAACAGTCACAATATTCTTCTCT
ATGAGGATGGGCATGCTGTGGTGGCAGATTTTGGAGAATCAAGATTTCTACAGTCTCTGGATGAAGACAACATGACAAAACAACCTGGGA
ACCTCCGTTGGATGGCTCCTGAGGTGTTCACGCAGTGCACTCGGTACACCATCAAAGCAGATGTCTTCAGCTATGCTCTGTGTCTGTGGG
AAATTCTCACTGGCGAAATTCCATTCGCTCATCTCAAGCCAGCGGCTGCGGCAGCAGACATGGCTTACCACCACATCAGACCTCCCATTG
GCTATTCCATTCCCAAGCCCATATCATCTCTGCTGATACGAGGGTGGAACGCATGTCCTGAAGGAAGACCCGAATTTTCTGAAGTTGTCA
TGAAGTTAGAAGAGTGTCTCTGCAACATTGAGCTGATGTCTCCTGCATCAAGTAACAGCAGTGGGTCTCTCTCACCTTCTTCTTCTTCTG
ATTGCCTGGTGAACCGGGGAGGACCTGGCCGGAGTCATGTGGCAGCATTAAGAAGTCGTTTCGAATTGGAATATGCTCTAAATGCAAGGT
CCTATGCTGCTTTGTCCCAAAGTGCTGGACAATATTCCTCTCAAGGTCTGTCTTTGGAGGAGATGAAAAGAAGTCTTCAATACACACCCA
TTGACAAATATGGCTATGTATCCGATCCCATGAGCTCAATGCATTTTCATTCTTGCCGAAATAGTAGCAGCTTTGAGGACAGCAGCTGAC
AGCATTCGGCGTATACCTAAGGAGAGTTTTTTCCCCGAACTGACAGCAACGATTCCAACCACGGCAAGCTGGCTTCCAACTATAACATTT
TACTCTCAAAGGTCTCCTTAAATTGGGCTTGTTTTTACTTGTCCTATTTAATTCCCCACTATTAGCAGGCTTTGGATTTGTGCCTAAGGA
ATAATATGCAAAAGAACCAAGACAGAATGTATATGAAGAATTGTTTTTAATTTTGTAAATTAAAAAAAAATTTAGATCGTTACTTGGAAA
TGGAGCCTAAGTCTGTGGTGGACAGATAATAATTATGTTTTCCTGGGCTGAATTATGTAGACTTGTGTTTGACAGCTATGGGTTTATTTC

>In-frame_ENST00000333916_ENST00000326637_TCGA-61-2095_CAAP1_chr9_26861063_-_TNNI3K_chr1_74832939_length(amino acids)=689AA_start in transcript=89_stop in transcript=2158
MTGKKSSREKRRKRSSQEAAAALAAPDIVPALASGSSGSTSGCGSAGGCGSVSCCGNANFSGSVTGGGSGGSCWGGSSVERSERRKRRST
DSSSVSGSLQQETKYILPTLEKELFLAEHSDLEEGGLDLTVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQ
EQLELLSEKKILKILEGDNGMDSDMEEEADDGSKMGSDLVSQQDICIDSASSVRENKQPEGLELKQGHDAIVTLLKHYKRPQDELPCNEY
SQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMF
CREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILL
YEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPI
GYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CAAP1-TNNI3K


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CAAP1-TNNI3K


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CAAP1-TNNI3K


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneTNNI3KC4015285CARDIAC CONDUCTION DISEASE WITH OR WITHOUT DILATED CARDIOMYOPATHY2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneTNNI3KC3495676Anorectal Malformations1GENOMICS_ENGLAND