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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ACACA-STAC2 (FusionGDB2 ID:1302)

Fusion Gene Summary for ACACA-STAC2

check button Fusion gene summary
Fusion gene informationFusion gene name: ACACA-STAC2
Fusion gene ID: 1302
HgeneTgene
Gene symbol

ACACA

STAC2

Gene ID

31

342667

Gene nameacetyl-CoA carboxylase alphaSH3 and cysteine rich domain 2
SynonymsACAC|ACACAD|ACC|ACC1|ACCA24b2|24b2/STAC2
Cytomap

17q12

17q12

Type of geneprotein-codingprotein-coding
Descriptionacetyl-CoA carboxylase 1ACC-alphaacetyl-Coenzyme A carboxylase alphaSH3 and cysteine-rich domain-containing protein 2SRC homology 3 and cysteine-rich domain-containing protein 2
Modification date2020031320200313
UniProtAcc

Q13085

.
Ensembl transtripts involved in fusion geneENST00000353139, ENST00000360679, 
ENST00000394406, ENST00000335166, 
ENST00000416895, ENST00000361253, 
ENST00000588142, ENST00000589665, 
ENST00000333461, 
Fusion gene scores* DoF score44 X 35 X 17=261809 X 6 X 6=324
# samples 5112
** MAII scorelog2(51/26180*10)=-5.68182403997375
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/324*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ACACA [Title/Abstract] AND STAC2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACACA(35479453)-STAC2(37374428), # samples:1
Anticipated loss of major functional domain due to fusion event.ACACA-STAC2 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ACACA-STAC2 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ACACA-STAC2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ACACA (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across STAC2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AXX000005ACACAchr17

35479453

-STAC2chr17

37374428

-


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Fusion Gene ORF analysis for ACACA-STAC2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000353139ENST00000333461ACACAchr17

35479453

-STAC2chr17

37374428

-
In-frameENST00000360679ENST00000333461ACACAchr17

35479453

-STAC2chr17

37374428

-
Frame-shiftENST00000394406ENST00000333461ACACAchr17

35479453

-STAC2chr17

37374428

-
Frame-shiftENST00000335166ENST00000333461ACACAchr17

35479453

-STAC2chr17

37374428

-
intron-3CDSENST00000416895ENST00000333461ACACAchr17

35479453

-STAC2chr17

37374428

-
In-frameENST00000361253ENST00000333461ACACAchr17

35479453

-STAC2chr17

37374428

-
intron-3CDSENST00000588142ENST00000333461ACACAchr17

35479453

-STAC2chr17

37374428

-
intron-3CDSENST00000589665ENST00000333461ACACAchr17

35479453

-STAC2chr17

37374428

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000353139ACACAchr1735479453-ENST00000333461STAC2chr1737374428-9522662046177652434
ENST00000360679ACACAchr1735479453-ENST00000333461STAC2chr1737374428-9190628829774332378
ENST00000361253ACACAchr1735479453-ENST00000333461STAC2chr1737374428-36257231951868557

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000353139ENST00000333461ACACAchr1735479453-STAC2chr1737374428-0.0004271860.9995728
ENST00000360679ENST00000333461ACACAchr1735479453-STAC2chr1737374428-0.0004233940.9995766
ENST00000361253ENST00000333461ACACAchr1735479453-STAC2chr1737374428-0.019229770.98077023

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Fusion Genomic Features for ACACA-STAC2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ACACA-STAC2


check button Go to

FGviewer for the breakpoints of chr17:35479453-chr17:37374428

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ACACA

Q13085

.
FUNCTION: Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis (PubMed:20952656, PubMed:20457939, PubMed:29899443). This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA (PubMed:20952656, PubMed:20457939, PubMed:29899443). {ECO:0000269|PubMed:20457939, ECO:0000269|PubMed:20952656, ECO:0000269|PubMed:29899443}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACACAchr17:35479453chr17:37374428ENST00000335166-4855117_6181931.02269.0DomainBiotin carboxylation
HgeneACACAchr17:35479453chr17:37374428ENST00000335166-48551576_19141931.02269.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35479453chr17:37374428ENST00000335166-4855275_4661931.02269.0DomainATP-grasp
HgeneACACAchr17:35479453chr17:37374428ENST00000335166-4855745_8191931.02269.0DomainBiotinyl-binding
HgeneACACAchr17:35479453chr17:37374428ENST00000353139-4956117_6182046.02384.0DomainBiotin carboxylation
HgeneACACAchr17:35479453chr17:37374428ENST00000353139-49561576_19142046.02384.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35479453chr17:37374428ENST00000353139-4956275_4662046.02384.0DomainATP-grasp
HgeneACACAchr17:35479453chr17:37374428ENST00000353139-4956745_8192046.02384.0DomainBiotinyl-binding
HgeneACACAchr17:35479453chr17:37374428ENST00000360679-4754117_6181951.02289.0DomainBiotin carboxylation
HgeneACACAchr17:35479453chr17:37374428ENST00000360679-47541576_19141951.02289.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35479453chr17:37374428ENST00000360679-4754275_4661951.02289.0DomainATP-grasp
HgeneACACAchr17:35479453chr17:37374428ENST00000360679-4754745_8191951.02289.0DomainBiotinyl-binding
HgeneACACAchr17:35479453chr17:37374428ENST00000394406-4956117_6182009.02347.0DomainBiotin carboxylation
HgeneACACAchr17:35479453chr17:37374428ENST00000394406-49561576_19142009.02347.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35479453chr17:37374428ENST00000394406-4956275_4662009.02347.0DomainATP-grasp
HgeneACACAchr17:35479453chr17:37374428ENST00000394406-4956745_8192009.02347.0DomainBiotinyl-binding
HgeneACACAchr17:35479453chr17:37374428ENST00000335166-4855315_3201931.02269.0Nucleotide bindingATP
HgeneACACAchr17:35479453chr17:37374428ENST00000353139-4956315_3202046.02384.0Nucleotide bindingATP
HgeneACACAchr17:35479453chr17:37374428ENST00000360679-4754315_3201951.02289.0Nucleotide bindingATP
HgeneACACAchr17:35479453chr17:37374428ENST00000394406-4956315_3202009.02347.0Nucleotide bindingATP
TgeneSTAC2chr17:35479453chr17:37374428ENST0000033346101170_10130.0412.0Compositional biasNote=Pro-rich
TgeneSTAC2chr17:35479453chr17:37374428ENST00000333461011292_35130.0412.0DomainSH3 1
TgeneSTAC2chr17:35479453chr17:37374428ENST00000333461011354_41130.0412.0DomainSH3 2
TgeneSTAC2chr17:35479453chr17:37374428ENST00000333461011110_16130.0412.0Zinc fingerPhorbol-ester/DAG-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACACAchr17:35479453chr17:37374428ENST00000335166-48551918_22341931.02269.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35479453chr17:37374428ENST00000353139-49561918_22342046.02384.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35479453chr17:37374428ENST00000360679-47541918_22341951.02289.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35479453chr17:37374428ENST00000394406-49561918_22342009.02347.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35479453chr17:37374428ENST00000335166-48551576_22341931.02269.0RegionCarboxyltransferase
HgeneACACAchr17:35479453chr17:37374428ENST00000353139-49561576_22342046.02384.0RegionCarboxyltransferase
HgeneACACAchr17:35479453chr17:37374428ENST00000360679-47541576_22341951.02289.0RegionCarboxyltransferase
HgeneACACAchr17:35479453chr17:37374428ENST00000394406-49561576_22342009.02347.0RegionCarboxyltransferase


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Fusion Gene Sequence for ACACA-STAC2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000353139_ENST00000333461_XX000005_ACACA_chr17_35479453_-_STAC2_chr17_37374428_length(transcript)=9522nt_BP=6620nt
GCCCTCTTGGCCTTTTCCCGGTCCCCGCCGCGCGCCTGCTGCTGTCCCCGTGCCCGAGGACTGGGAGGATGGGGCTGAGCCGCTTGCCTG
ACTTTTGATCCGACCAGTAATCACTTTGCCCGTGTGGCGCGTGGCCCGTTGCCTGAGGCTTCCTGGCGCGTGGGGCTGTTTGGTCCCCTC
CGGAGTGCGGTGAGGCGGGCCGAGCCGGGACTGCCTGGGTTTGGGGATAACGTTCCCATCTCCACCCCTGTTGCAGCAAGGGAAATTGAG
GCTGAGGGAACTGGGCCCAGGGACGGCGAGCCGTGGCTGCCTCTCCAGTCCGGGCCCCGAAGGGCTGCTCGTGGATGAACCAGACTGATT
TTAAGGGGTGAAGAGGGTGCGTTTCAATCAGATGCTTCTGGAACGTCGAAATTGTCTTCTTTGGAAAGAACCATCCCCTCTTTGGGCTTC
AGAGGCCCAAATTGAGGCGCAATGATGAGAGGATGTGGTGGTCTACTCTGATGTCAATCTTGAGGGCTAGGTCTTTCTGGAAGTGGATAT
CTACTCAGACAGTAAGAATTATAAGAGCTGTAAGAGCTCATTTTGGAGGAATAATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGC
TGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAGATAACTCAGAGGATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGG
AGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAGATACACTCTCTGATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCT
TGCACATAAGGTCCAGCATGTCTGGCTTGCACCTAGTAAAGCAGGGCCGAGACAGAAAGAAAATAGATTCTCAACGAGATTTCACTGTGG
CTTCTCCAGCAGAATTTGTTACTCGCTTTGGGGGAAATAAAGTGATTGAGAAGGTTCTTATTGCTAACAATGGCATTGCAGCAGTGAAAT
GCATGCGGTCTATCCGTAGGTGGTCTTATGAAATGTTTCGAAATGAACGTGCAATTAGATTCGTTGTCATGGTCACACCTGAAGACCTTA
AAGCCAATGCAGAATACATTAAGATGGCAGATCACTATGTGCCAGTGCCTGGAGGACCAAACAACAACAACTATGCAAATGTGGAATTAA
TTCTTGATATTGCTAAAAGGATCCCAGTACAAGCAGTGTGGGCTGGCTGGGGTCATGCTTCTGAGAATCCCAAACTACCGGAACTTCTCT
TGAAAAATGGCATTGCCTTCATGGGTCCTCCAAGCCAGGCCATGTGGGCTTTAGGGGATAAGATTGCATCTTCCATAGTGGCTCAAACTG
CAGGTATCCCAACTCTTCCCTGGAGCGGCAGTGGTCTTCGTGTGGACTGGCAGGAAAATGATTTTTCAAAACGTATCTTAAATGTTCCCC
AGGAGCTATATGAAAAAGGTTATGTGAAAGATGTGGATGATGGGCTACAGGCAGCTGAGGAAGTTGGATATCCAGTAATGATCAAGGCCT
CAGAGGGAGGAGGAGGGAAGGGAATTAGAAAAGTCAACAATGCAGATGACTTCCCTAATCTCTTCAGACAGGTTCAAGCTGAAGTTCCTG
GATCTCCCATATTTGTGATGAGACTAGCCAAACAATCTCGTCATCTGGAGGTGCAGATCTTAGCGGACCAATATGGCAATGCTATCTCTT
TGTTTGGTCGTGATTGCTCTGTACAACGCAGGCATCAGAAGATTATTGAAGAAGCACCTGCTACTATTGCTACTCCAGCAGTATTTGAAC
ACATGGAACAGTGTGCGGTGAAACTTGCCAAAATGGTGGGTTATGTGAGTGCTGGGACTGTGGAATACCTGTACAGCCAGGATGGCAGCT
TCTACTTTCTGGAATTGAATCCTCGGCTGCAGGTAGAGCACCCTTGTACAGAGATGGTGGCTGATGTCAATCTCCCTGCAGCACAGCTCC
AGATTGCCATGGGGATTCCTCTATATAGAATCAAGGATATCCGTATGATGTATGGGGTATCTCCCTGGGGTGATTCTCCCATTGATTTTG
AAGATTCTGCACACGTTCCTTGTCCAAGGGGCCATGTTATTGCTGCTCGGATCACTAGTGAAAATCCAGATGAGGGTTTTAAGCCCAGCT
CAGGAACAGTTCAGGAGCTAAATTTCCGCAGCAATAAGAATGTTTGGGGATATTTCAGTGTTGCTGCTGCAGGGGGACTTCATGAATTTG
CTGATTCTCAGTTTGGTCACTGCTTTTCTTGGGGAGAAAACAGAGAAGAGGCAATTTCAAACATGGTGGTGGCTTTGAAGGAGCTGTCTA
TTCGGGGTGACTTTCGAACTACAGTTGAATACCTGATCAAATTGTTAGAGACTGAAAGCTTTCAGATGAACAGAATTGATACTGGCTGGC
TGGACAGACTGATAGCAGAAAAAGTACAGGCTGAGCGACCTGACACCATGTTGGGGGTTGTGTGTGGTGCCCTCCACGTGGCAGATGTGA
GCCTGCGGAATAGCGTCTCTAACTTCCTTCACTCCTTAGAAAGGGGTCAAGTCCTTCCTGCTCATACACTTCTGAATACAGTAGATGTTG
AACTTATCTATGAGGGAGTCAAGTATGTACTTAAGGTGACTCGACAGTCCCCCAACTCCTATGTGGTGATCATGAATGGCTCATGTGTAG
AAGTAGATGTACATCGGCTGAGTGACGGTGGACTGCTCTTGTCCTATGATGGCAGCAGTTATACTACGTATATGAAAGAGGAAGTGGATA
GATATCGCATCACAATTGGCAATAAAACCTGTGTGTTTGAGAAGGAAAATGACCCATCGGTGATGCGCTCACCTTCTGCTGGGAAGTTAA
TCCAGTACATTGTAGAAGATGGAGGTCATGTGTTTGCCGGCCAGTGCTATGCTGAGATTGAGGTAATGAAGATGGTAATGACCTTAACAG
CTGTGGAGTCTGGCTGTATCCATTACGTCAAGCGACCTGGAGCAGCTCTTGACCCTGGCTGTGTACTAGCCAAAATGCAACTGGACAACC
CCAGCAAGGTTCAGCAGGCTGAACTTCACACAGGTAGTCTGCCACGGATCCAGAGCACGGCACTCAGAGGCGAGAAACTCCATCGAGTGT
TCCATTATGTCCTGGATAATCTGGTCAATGTAATGAATGGATACTGCCTTCCAGATCCTTTCTTTAGCAGCAAGGTAAAAGACTGGGTAG
AGCGATTGATGAAAACCCTCAGAGATCCCTCCCTGCCTCTCCTAGAATTGCAAGATATTATGACCAGTGTGTCTGGCCGCATTCCCCCCA
ATGTGGAGAAGTCTATCAAGAAGGAAATGGCTCAGTATGCTAGCAACATCACATCAGTCCTCTGTCAGTTTCCCAGCCAGCAGATTGCAA
ACATCCTAGATAGCCATGCAGCTACATTGAACCGGAAATCTGAACGGGAAGTCTTCTTTATGAATACTCAGAGCATTGTTCAGCTGGTAC
AGAGGTACCGAAGTGGCATCCGAGGCCACATGAAGGCTGTGGTGATGGATCTGCTCCGGCAGTACCTGCGAGTAGAGACACAATTCCAGA
ATGGTCACTATGACAAATGTGTATTCGCCCTCCGAGAAGAGAATAAAAGTGACATGAACACTGTACTGAACTACATCTTCTCTCACGCTC
AAGTCACCAAGAAGAATCTTCTGGTCACAATGCTTATTGATCAGTTGTGTGGCCGGGACCCTACTCTCACTGATGAGCTGCTGAATATTC
TCACAGAGCTAACTCAACTCAGTAAGACCACCAATGCCAAAGTAGCACTTCGAGCACGCCAGGTTCTTATTGCCTCCCATTTGCCATCAT
ATGAGCTTCGCCATAACCAAGTAGAGTCTATCTTCCTATCAGCTATTGACATGTATGGACATCAATTTTGCATTGAGAACCTGCAGAAAC
TCATCCTATCAGAAACATCTATTTTTGATGTCCTACCAAACTTCTTCTATCACAGCAACCAAGTAGTGAGGATGGCAGCTCTGGAGGTGT
ATGTTCGAAGGGCTTATATTGCCTATGAACTTAACAGCGTACAACACCGCCAGCTTAAGGACAACACCTGTGTGGTGGAATTCCAGTTCA
TGCTGCCCACATCTCATCCAAACAGAGGGAACATCCCTACGCTAAACAGAATGTCCTTCTCCTCCAACCTCAACCACTATGGCATGACCC
ATGTAGCTAGTGTCAGCGATGTACTGTTGGACAACTCATTCACTCCACCTTGTCAGCGGATGGGCGGAATGGTCTCTTTTCGGACTTTTG
AAGATTTTGTCAGGATCTTTGATGAAGTGATGGGCTGCTTCTCTGACTCCCCACCCCAGAGTCCCACATTCCCTGAGGCAGGTCACACGT
CTCTTTATGATGAGGATAAGGTTCCCAGGGATGAACCAATTCACATTCTCAATGTGGCTATCAAGACTGACTGTGATATTGAGGATGACA
GGCTGGCAGCTATGTTCAGAGAATTTACCCAGCAAAATAAAGCTACCCTGGTTGACCATGGGATCCGGCGCCTTACTTTCCTGGTTGCAC
AAAAGGATTTCAGAAAGCAGGTCAACTATGAGGTGGATCGGAGATTTCATAGAGAATTCCCTAAATTTTTTACATTCCGAGCAAGGGATA
AGTTTGAGGAGGATCGTATCTATCGTCATCTGGAGCCTGCTCTGGCTTTCCAGTTAGAGCTGAACCGGATGAGAAATTTTGACCTCACTG
CCATTCCATGTGCTAATCACAAGATGCACCTGTATCTCGGGGCAGCCAAGGTGGAAGTGGGCACAGAAGTGACAGACTACAGGTTCTTTG
TTCGTGCAATCATCAGGCATTCTGATCTGGTCACCAAGGAAGCTTCTTTTGAATATCTGCAAAATGAAGGGGAGCGGCTACTCCTGGAAG
CCATGGATGAGTTGGAAGTTGCTTTTAACAATACAAATGTCCGCACTGACTGTAACCACATCTTCCTCAACTTTGTGCCCACGGTTATCA
TGGACCCATCAAAGATTGAGGAATCCGTGCGGAGCATGGTAATGCGGTATGGAAGTCGCCTGTGGAAATTGCGCGTCCTCCAGGCAGAAC
TGAAAATCAACATTCGCCTGACGCCAACTGGAAAAGCAATTCCCATCCGCCTCTTCCTGACAAACGAGTCTGGCTATTACTTGGATATCA
GCCTATACAAGGAAGTGACTGACTCCAGGACAGCACAGATCATGTTTCAGGCATATGGAGACAAACAGGGACCACTGCATGGAATGTTAA
TCAATACTCCATATGTGACCAAAGACCTGCTGCAATCAAAGAGGTTCCAGGCACAATCCTTAGGGACAACATACATATATGATATCCCAG
AGATGTTTCGGCAGTCCCTGATCAAACTCTGGGAGTCTATGTCCACTCAAGCATTTCTTCCATCTCCCCCTCTGCCTTCTGACATGCTGA
CTTACACTGAACTGGTACTGGATGATCAAGGTCAGCTGGTCCACATGAACAGGCTTCCAGGAGGAAATGAGATTGGCATGGTAGCTTGGA
AAATGACCTTTAAAAGTCCTGAATATCCAGAAGGCCGAGATATCATTGTTATTGGCAATGACATCACATACCGAATTGGGTCCTTTGGGC
CTCAAGAGGATTTGTTATTTCTCAGAGCTTCCGAACTTGCTAGGGCAGAAGGTATTCCACGCATCTATGTATCAGCCAACAGTGGAGCAA
GAATCGGACTGGCAGAAGAAATTCGCCATATGTTTCATGTGGCCTGGGTAGATCCTGAGGATCCTTACAAGGGATACAGGTATTTATATC
TGACTCCTCAAGATTATAAGAGAGTCAGTGCTCTCAACTCTGTCCATTGTGAACACGTGGAAGATGAAGGAGAATCCAGGTACAAGATAA
CAGATATTATTGGGAAAGAAGAGGGAATTGGACCCGAGAACCTTCGAGGTTCTGGAATGATTGCTGGAGAATCCTCATTGGCCTATAATG
AGATCATTACCATCAGCCTGGTGACGTGCCGGGCCATTGGGATTGGGGCTTACCTTGTCCGGCTGGGACAGAGAACCATCCAGGTTGAGA
ATTCTCACTTAATTCTAACAGGAGCTGGAGCCCTCAACAAAGTCCTCGGGCGGGAAGTGTACACCTCCAATAACCAGCTGGGGGGCATCC
AGATTATGCACAACAATGGGGTGACCCACTGCACTGTGTGTGATGACTTTGAAGGGGTTTTCACTGTCCTGCACTGGCTGTCTTACATGC
CCAAGAGCGTGCACAGTTCAGTTCCTCTTCTGAACTCAAAGGATCCTATAGACAGAATCATCGAGTTTGTTCCCACAAAGACCCCATACG
ATCCTCGATGGATGCTAGCAGGCCGTCCTCACCCAACCCAAAAAGGTCAGTGGTTGAGTGGCTTTTTTGACTATGGATCTTTCTCAGAGA
TTATGCAGCCCTGGGCACAGACTGTGGTGGTTGGTAGAGCCAGGCTAGGAGGAATACCTGTGGGAGTTGTTGCTGTAGAAACCCGAACAG
TAGAACTAAGTATCCCAGCTGATCCAGCAAACCTGGATTCTGAAGCCAAGCTCCAGCGATTCAAGCGCTCCCTCTCCCTCAAGACCATCC
TCCGAAGTAAGAGCTTGGAGAACTTCTTCCTTCGCTCGGGCTCTGAGCTCAAGTGCCCCACCGAGGTGCTGCTGACGCCCCCAACCCCAC
TGCCCCCTCCCTCCCCACCACCCACAGCCTCGGACAGGGGCCTGGCTACCCCATCCCCCTCCCCATGCCCAGTCCCACGCCCCCTGGCAG
CGCTCAAACCAGTGAGGCTGCACAGCTTCCAGGAACATGTCTTCAAGCGAGCTAGCCCTTGTGAGCTGTGCCACCAGCTCATCGTAGGAA
ACTCCAAACAGGGCTTGCGATGTAAGATGTGCAAAGTCAGCGTCCACCTCTGGTGCTCTGAGGAGATCTCCCACCAGCAATGCCCAGGCA
AGACGTCCACCTCCTTCCGCCGCAACTTCAGTTCCCCTCTCCTGGTGCATGAGCCGCCACCAGTCTGTGCCACAAGCAAAGAGTCCCCAC
CCACTGGGGACAGTGGGAAGGTGGACCCTGTCTACGAGACCCTGCGCTATGGCACCTCCCTGGCACTGATGAACCGCTCCAGTTTCAGCA
GCACCTCTGAGTCCCCGACAAGGAGCCTGAGTGAGCGGGATGAGCTGACCGAGGATGGGGAAGGCAGCATCCGCAGCTCTGAGGAGGGGC
CTGGTGACAGTGCATCTCCAGTATTCACAGCCCCAGCAGAGAGTGAAGGGCCAGGACCAGAGGAGAAGAGTCCTGGACAGCAGCTCCCCA
AAGCCACCCTGCGGAAGGATGTGGGGCCCATGTACTCCTACGTTGCACTCTACAAGTTTCTGCCCCAGGAGAACAATGATCTGGCTCTGC
AGCCTGGAGATCGGATCATGCTGGTGGATGACTCTAACGAGGACTGGTGGAAGGGCAAGATCGGCGACCGGGTTGGCTTCTTCCCAGCTA
ATTTTGTGCAACGGGTGAGGCCAGGCGAGAATGTTTGGCGCTGCTGCCAACCCTTCTCCGGGAACAAGGAACAGGGTTACATGAGCCTCA
AGGAGAACCAGATCTGCGTGGGCGTGGGCAGAAGCAAGGATGCTGACGGCTTCATCCGCGTCAGCAGTGGCAAGAAGCGGGGCCTGGTGC
CAGTCGACGCCCTGACTGAGATCTGAGAGGAGCCAAGGGAACCCAGATGACACCCTTGCCCATGCCTGGACCTTGCTTCTGGCCAGGGAG
GGGATCAGGCCCCCTTGTCCACTCCATACCCTTCCTCCCTCTGTCCCTCTCCTAGGTGCCACTTACCGTGGCTTAGGAGCCTTTTGTACT
GGGGAAGATTTTATTTCTTGGGTGGGGTGCCCTGAGTGGGTTGATCCTCTGGGACTTGGCGGGGATGGGGTGGGGTGGGAGGGAATGAGG
AAGCTACAGGTAGGTCCACCCAACGCCCAGGCACCCCAGTCTACTTGCTGGGCTGAGTCCAGCCCTGGGGAAGATTCCTGGGGAATTTAT
TTGCTGCTTCTCCCAGCCTTCCCCTGCCCACACCACCTGCGCATGCCTGGCACACCCCTCTCCCCACAGAGCCTCTGCTTGGGTCTATGT
GTGTGTGACCGTGCATCTGCTCCTTTGCAAGTGGGGTCTTGGGAGCAGGCCTTTTTGTGTCCTCGGCCCTCCACCCTTGGTGGGGAGGGG
ACCCAGGACCATAGGAAGGTCCTGAGTCCACCTCCTGGTCTCCACCTCTGTCATTCCGTCAATTCTCAGGAAAGTTTTGCAGGAATCTCT
CCCGTTACTTGAAACCTGGGCGGACAGATGAGGGGAAGGCTGAGGTCCCTGGAAGGTGTAACAAATCAGAGACTATCTGTTCAAGTAGAA
AACCCAAGAGCTGGCCAGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACCTGAGGTCAGGAGT
TCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAGTACGAAACTTAGCCAGGCATGATGGGGGTCTGCCTGTAATGCC
AGCTACTCCAGAGGCTGAGGCAAGAGAATCACTTGAACCCGGGAGGCGGAGGTTTCAGTGAGCCGAGATTGCACCATTGCACCCCAGCCT
GGGCAACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAGAAAGAAAGAAAAGGAAACCCAAGAGCTGCCTGGACACACGGAAACCCAACT
GAGAACAAAATCCTGGCCCGTGCTTGGTCAAAGCAAACCCATTTCACTGTCAGGACCCCCGGTCACACAGGAACCACCCGCCAGGGGAGC
CTGTGACTGTCAGTTCCTGTCCCAGGCTTTGCCCGGCCGCCCCAGGAACCCAACCCTCTGGGCTGACCTTTCTCCTGCTTCTCTCCAGGC
TCTGCAGGGGACAGGGCAGGTGCTGCAGGAGCCCCTTTGCTGGCTTTATCTGCTCCCTTGTTCTGGACACAGAGCCCTGGGAAAAAGAGG
GGGTGGAAGACAGACAAGGAAGGTGGAATGTTCTGTTTTGGCCACCAGGAAATGGGGTGGGGTGGGCATACACAGAGAGGACCCCTCTCT
TAATACAGCTGCTTTTCTCGGTGCCAACCTCCCTCCCCCAAGCTCAGATCCTCCTCTTATGCCCTTGATTGTGCCAGCCCATGCCACCCC
CATCCTGGGCACAGTTACACCCTCCCATGCAGTGGGAGAAACACAGACCCTCGTACCCAAAGGCCCCTGCCCCACTTCTCCCCCACAAAG
CGGGGTCTCAAGCCACACTGCCCTGTTTGCTGCCATGAGGCCCCCCCCCCCAGCAATATCCCAGGGGCGGGCCCAATGCCCACTGTACAT

>In-frame_ENST00000353139_ENST00000333461_XX000005_ACACA_chr17_35479453_-_STAC2_chr17_37374428_length(amino acids)=2434AA_start in transcript=461_stop in transcript=7765
MRRNDERMWWSTLMSILRARSFWKWISTQTVRIIRAVRAHFGGIMDEPSPLAQPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKE
GSLSPASVGSDTLSDLGISSLQDGLALHIRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRS
IRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNG
IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGG
GGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQ
CAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPIDFEDSA
HVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGD
FRTTVEYLIKLLETESFQMNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLPAHTLLNTVDVELIY
EGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYI
VEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYV
LDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILD
SHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTK
KNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILS
ETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVAS
VSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPPQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAA
MFREFTQQNKATLVDHGIRRLTFLVAQKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPC
ANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPS
KIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTP
YVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTF
KSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWVDPEDPYKGYRYLYLTPQ
DYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHL
ILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKTPYDPRW
MLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKLQRFKRSLSLKTILRSK
SLENFFLRSGSELKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPVRLHSFQEHVFKRASPCELCHQLIVGNSKQ
GLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLALMNRSSFSSTSE
SPTRSLSERDELTEDGEGSIRSSEEGPGDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVALYKFLPQENNDLALQPGD
RIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDA

--------------------------------------------------------------
>In-frame_ENST00000360679_ENST00000333461_XX000005_ACACA_chr17_35479453_-_STAC2_chr17_37374428_length(transcript)=9190nt_BP=6288nt
GGCAGCCAGGAGAGGCAGTGGAGCTTTTCTCCGTTGACTGTCAGAAGAAAGTGACTGTTGTTGAAAATGTTTGCTGCAACTAAAGGAGAG
CTGCTAAGATCTACTTTCTAGTTAAACAAGCTTTTATATTTCTCCCCGGCTCCTCTCAGTTCCCTTGGGAAATCAACTAATTGTGTGTGT
AAGCTAAGTGTGTGGAGGAGAGAAGATGCAAAAAGGAAGAGAAAGGTGGGGAAAGAAGGAAATTGGGAACAATTAGACAAAAAGACTATA
GTTTGAGGCCATCAGGAGTATTCTAGTCTGACTGAAGCCAGGCAGAAGGCACAGTATCTCTTGTCCTCCTGGGTTTTAAGCAGCTGCAAC
AGGAGGAGGAACTGCGGCTTGTGTTTACAAGGCCGAAATCTGAAGAAAAAGCTTCCATTCTTTTCCCATCTTGATATGGAGGGTTCTCCA
GAGGAAAATAAGGAAATGAGATATTACATGCTTCAAAGGTCCAGCATGTCTGGCTTGCACCTAGTAAAGCAGGGCCGAGACAGAAAGAAA
ATAGATTCTCAACGAGATTTCACTGTGGCTTCTCCAGCAGAATTTGTTACTCGCTTTGGGGGAAATAAAGTGATTGAGAAGGTTCTTATT
GCTAACAATGGCATTGCAGCAGTGAAATGCATGCGGTCTATCCGTAGGTGGTCTTATGAAATGTTTCGAAATGAACGTGCAATTAGATTC
GTTGTCATGGTCACACCTGAAGACCTTAAAGCCAATGCAGAATACATTAAGATGGCAGATCACTATGTGCCAGTGCCTGGAGGACCAAAC
AACAACAACTATGCAAATGTGGAATTAATTCTTGATATTGCTAAAAGGATCCCAGTACAAGCAGTGTGGGCTGGCTGGGGTCATGCTTCT
GAGAATCCCAAACTACCGGAACTTCTCTTGAAAAATGGCATTGCCTTCATGGGTCCTCCAAGCCAGGCCATGTGGGCTTTAGGGGATAAG
ATTGCATCTTCCATAGTGGCTCAAACTGCAGGTATCCCAACTCTTCCCTGGAGCGGCAGTGGTCTTCGTGTGGACTGGCAGGAAAATGAT
TTTTCAAAACGTATCTTAAATGTTCCCCAGGAGCTATATGAAAAAGGTTATGTGAAAGATGTGGATGATGGGCTACAGGCAGCTGAGGAA
GTTGGATATCCAGTAATGATCAAGGCCTCAGAGGGAGGAGGAGGGAAGGGAATTAGAAAAGTCAACAATGCAGATGACTTCCCTAATCTC
TTCAGACAGGTTCAAGCTGAAGTTCCTGGATCTCCCATATTTGTGATGAGACTAGCCAAACAATCTCGTCATCTGGAGGTGCAGATCTTA
GCGGACCAATATGGCAATGCTATCTCTTTGTTTGGTCGTGATTGCTCTGTACAACGCAGGCATCAGAAGATTATTGAAGAAGCACCTGCT
ACTATTGCTACTCCAGCAGTATTTGAACACATGGAACAGTGTGCGGTGAAACTTGCCAAAATGGTGGGTTATGTGAGTGCTGGGACTGTG
GAATACCTGTACAGCCAGGATGGCAGCTTCTACTTTCTGGAATTGAATCCTCGGCTGCAGGTAGAGCACCCTTGTACAGAGATGGTGGCT
GATGTCAATCTCCCTGCAGCACAGCTCCAGATTGCCATGGGGATTCCTCTATATAGAATCAAGGATATCCGTATGATGTATGGGGTATCT
CCCTGGGGTGATTCTCCCATTGATTTTGAAGATTCTGCACACGTTCCTTGTCCAAGGGGCCATGTTATTGCTGCTCGGATCACTAGTGAA
AATCCAGATGAGGGTTTTAAGCCCAGCTCAGGAACAGTTCAGGAGCTAAATTTCCGCAGCAATAAGAATGTTTGGGGATATTTCAGTGTT
GCTGCTGCAGGGGGACTTCATGAATTTGCTGATTCTCAGTTTGGTCACTGCTTTTCTTGGGGAGAAAACAGAGAAGAGGCAATTTCAAAC
ATGGTGGTGGCTTTGAAGGAGCTGTCTATTCGGGGTGACTTTCGAACTACAGTTGAATACCTGATCAAATTGTTAGAGACTGAAAGCTTT
CAGATGAACAGAATTGATACTGGCTGGCTGGACAGACTGATAGCAGAAAAAGTACAGGCTGAGCGACCTGACACCATGTTGGGGGTTGTG
TGTGGTGCCCTCCACGTGGCAGATGTGAGCCTGCGGAATAGCGTCTCTAACTTCCTTCACTCCTTAGAAAGGGGTCAAGTCCTTCCTGCT
CATACACTTCTGAATACAGTAGATGTTGAACTTATCTATGAGGGAGTCAAGTATGTACTTAAGGTGACTCGACAGTCCCCCAACTCCTAT
GTGGTGATCATGAATGGCTCATGTGTAGAAGTAGATGTACATCGGCTGAGTGACGGTGGACTGCTCTTGTCCTATGATGGCAGCAGTTAT
ACTACGTATATGAAAGAGGAAGTGGATAGATATCGCATCACAATTGGCAATAAAACCTGTGTGTTTGAGAAGGAAAATGACCCATCGGTG
ATGCGCTCACCTTCTGCTGGGAAGTTAATCCAGTACATTGTAGAAGATGGAGGTCATGTGTTTGCCGGCCAGTGCTATGCTGAGATTGAG
GTAATGAAGATGGTAATGACCTTAACAGCTGTGGAGTCTGGCTGTATCCATTACGTCAAGCGACCTGGAGCAGCTCTTGACCCTGGCTGT
GTACTAGCCAAAATGCAACTGGACAACCCCAGCAAGGTTCAGCAGGCTGAACTTCACACAGGTAGTCTGCCACGGATCCAGAGCACGGCA
CTCAGAGGCGAGAAACTCCATCGAGTGTTCCATTATGTCCTGGATAATCTGGTCAATGTAATGAATGGATACTGCCTTCCAGATCCTTTC
TTTAGCAGCAAGGTAAAAGACTGGGTAGAGCGATTGATGAAAACCCTCAGAGATCCCTCCCTGCCTCTCCTAGAATTGCAAGATATTATG
ACCAGTGTGTCTGGCCGCATTCCCCCCAATGTGGAGAAGTCTATCAAGAAGGAAATGGCTCAGTATGCTAGCAACATCACATCAGTCCTC
TGTCAGTTTCCCAGCCAGCAGATTGCAAACATCCTAGATAGCCATGCAGCTACATTGAACCGGAAATCTGAACGGGAAGTCTTCTTTATG
AATACTCAGAGCATTGTTCAGCTGGTACAGAGGTACCGAAGTGGCATCCGAGGCCACATGAAGGCTGTGGTGATGGATCTGCTCCGGCAG
TACCTGCGAGTAGAGACACAATTCCAGAATGGTCACTATGACAAATGTGTATTCGCCCTCCGAGAAGAGAATAAAAGTGACATGAACACT
GTACTGAACTACATCTTCTCTCACGCTCAAGTCACCAAGAAGAATCTTCTGGTCACAATGCTTATTGATCAGTTGTGTGGCCGGGACCCT
ACTCTCACTGATGAGCTGCTGAATATTCTCACAGAGCTAACTCAACTCAGTAAGACCACCAATGCCAAAGTAGCACTTCGAGCACGCCAG
GTTCTTATTGCCTCCCATTTGCCATCATATGAGCTTCGCCATAACCAAGTAGAGTCTATCTTCCTATCAGCTATTGACATGTATGGACAT
CAATTTTGCATTGAGAACCTGCAGAAACTCATCCTATCAGAAACATCTATTTTTGATGTCCTACCAAACTTCTTCTATCACAGCAACCAA
GTAGTGAGGATGGCAGCTCTGGAGGTGTATGTTCGAAGGGCTTATATTGCCTATGAACTTAACAGCGTACAACACCGCCAGCTTAAGGAC
AACACCTGTGTGGTGGAATTCCAGTTCATGCTGCCCACATCTCATCCAAACAGAGGGAACATCCCTACGCTAAACAGAATGTCCTTCTCC
TCCAACCTCAACCACTATGGCATGACCCATGTAGCTAGTGTCAGCGATGTACTGTTGGACAACTCATTCACTCCACCTTGTCAGCGGATG
GGCGGAATGGTCTCTTTTCGGACTTTTGAAGATTTTGTCAGGATCTTTGATGAAGTGATGGGCTGCTTCTCTGACTCCCCACCCCAGAGT
CCCACATTCCCTGAGGCAGGTCACACGTCTCTTTATGATGAGGATAAGGTTCCCAGGGATGAACCAATTCACATTCTCAATGTGGCTATC
AAGACTGACTGTGATATTGAGGATGACAGGCTGGCAGCTATGTTCAGAGAATTTACCCAGCAAAATAAAGCTACCCTGGTTGACCATGGG
ATCCGGCGCCTTACTTTCCTGGTTGCACAAAAGGATTTCAGAAAGCAGGTCAACTATGAGGTGGATCGGAGATTTCATAGAGAATTCCCT
AAATTTTTTACATTCCGAGCAAGGGATAAGTTTGAGGAGGATCGTATCTATCGTCATCTGGAGCCTGCTCTGGCTTTCCAGTTAGAGCTG
AACCGGATGAGAAATTTTGACCTCACTGCCATTCCATGTGCTAATCACAAGATGCACCTGTATCTCGGGGCAGCCAAGGTGGAAGTGGGC
ACAGAAGTGACAGACTACAGGTTCTTTGTTCGTGCAATCATCAGGCATTCTGATCTGGTCACCAAGGAAGCTTCTTTTGAATATCTGCAA
AATGAAGGGGAGCGGCTACTCCTGGAAGCCATGGATGAGTTGGAAGTTGCTTTTAACAATACAAATGTCCGCACTGACTGTAACCACATC
TTCCTCAACTTTGTGCCCACGGTTATCATGGACCCATCAAAGATTGAGGAATCCGTGCGGAGCATGGTAATGCGGTATGGAAGTCGCCTG
TGGAAATTGCGCGTCCTCCAGGCAGAACTGAAAATCAACATTCGCCTGACGCCAACTGGAAAAGCAATTCCCATCCGCCTCTTCCTGACA
AACGAGTCTGGCTATTACTTGGATATCAGCCTATACAAGGAAGTGACTGACTCCAGGACAGCACAGATCATGTTTCAGGCATATGGAGAC
AAACAGGGACCACTGCATGGAATGTTAATCAATACTCCATATGTGACCAAAGACCTGCTGCAATCAAAGAGGTTCCAGGCACAATCCTTA
GGGACAACATACATATATGATATCCCAGAGATGTTTCGGCAGTCCCTGATCAAACTCTGGGAGTCTATGTCCACTCAAGCATTTCTTCCA
TCTCCCCCTCTGCCTTCTGACATGCTGACTTACACTGAACTGGTACTGGATGATCAAGGTCAGCTGGTCCACATGAACAGGCTTCCAGGA
GGAAATGAGATTGGCATGGTAGCTTGGAAAATGACCTTTAAAAGTCCTGAATATCCAGAAGGCCGAGATATCATTGTTATTGGCAATGAC
ATCACATACCGAATTGGGTCCTTTGGGCCTCAAGAGGATTTGTTATTTCTCAGAGCTTCCGAACTTGCTAGGGCAGAAGGTATTCCACGC
ATCTATGTATCAGCCAACAGTGGAGCAAGAATCGGACTGGCAGAAGAAATTCGCCATATGTTTCATGTGGCCTGGGTAGATCCTGAGGAT
CCTTACAAGGGATACAGGTATTTATATCTGACTCCTCAAGATTATAAGAGAGTCAGTGCTCTCAACTCTGTCCATTGTGAACACGTGGAA
GATGAAGGAGAATCCAGGTACAAGATAACAGATATTATTGGGAAAGAAGAGGGAATTGGACCCGAGAACCTTCGAGGTTCTGGAATGATT
GCTGGAGAATCCTCATTGGCCTATAATGAGATCATTACCATCAGCCTGGTGACGTGCCGGGCCATTGGGATTGGGGCTTACCTTGTCCGG
CTGGGACAGAGAACCATCCAGGTTGAGAATTCTCACTTAATTCTAACAGGAGCTGGAGCCCTCAACAAAGTCCTCGGGCGGGAAGTGTAC
ACCTCCAATAACCAGCTGGGGGGCATCCAGATTATGCACAACAATGGGGTGACCCACTGCACTGTGTGTGATGACTTTGAAGGGGTTTTC
ACTGTCCTGCACTGGCTGTCTTACATGCCCAAGAGCGTGCACAGTTCAGTTCCTCTTCTGAACTCAAAGGATCCTATAGACAGAATCATC
GAGTTTGTTCCCACAAAGACCCCATACGATCCTCGATGGATGCTAGCAGGCCGTCCTCACCCAACCCAAAAAGGTCAGTGGTTGAGTGGC
TTTTTTGACTATGGATCTTTCTCAGAGATTATGCAGCCCTGGGCACAGACTGTGGTGGTTGGTAGAGCCAGGCTAGGAGGAATACCTGTG
GGAGTTGTTGCTGTAGAAACCCGAACAGTAGAACTAAGTATCCCAGCTGATCCAGCAAACCTGGATTCTGAAGCCAAGCTCCAGCGATTC
AAGCGCTCCCTCTCCCTCAAGACCATCCTCCGAAGTAAGAGCTTGGAGAACTTCTTCCTTCGCTCGGGCTCTGAGCTCAAGTGCCCCACC
GAGGTGCTGCTGACGCCCCCAACCCCACTGCCCCCTCCCTCCCCACCACCCACAGCCTCGGACAGGGGCCTGGCTACCCCATCCCCCTCC
CCATGCCCAGTCCCACGCCCCCTGGCAGCGCTCAAACCAGTGAGGCTGCACAGCTTCCAGGAACATGTCTTCAAGCGAGCTAGCCCTTGT
GAGCTGTGCCACCAGCTCATCGTAGGAAACTCCAAACAGGGCTTGCGATGTAAGATGTGCAAAGTCAGCGTCCACCTCTGGTGCTCTGAG
GAGATCTCCCACCAGCAATGCCCAGGCAAGACGTCCACCTCCTTCCGCCGCAACTTCAGTTCCCCTCTCCTGGTGCATGAGCCGCCACCA
GTCTGTGCCACAAGCAAAGAGTCCCCACCCACTGGGGACAGTGGGAAGGTGGACCCTGTCTACGAGACCCTGCGCTATGGCACCTCCCTG
GCACTGATGAACCGCTCCAGTTTCAGCAGCACCTCTGAGTCCCCGACAAGGAGCCTGAGTGAGCGGGATGAGCTGACCGAGGATGGGGAA
GGCAGCATCCGCAGCTCTGAGGAGGGGCCTGGTGACAGTGCATCTCCAGTATTCACAGCCCCAGCAGAGAGTGAAGGGCCAGGACCAGAG
GAGAAGAGTCCTGGACAGCAGCTCCCCAAAGCCACCCTGCGGAAGGATGTGGGGCCCATGTACTCCTACGTTGCACTCTACAAGTTTCTG
CCCCAGGAGAACAATGATCTGGCTCTGCAGCCTGGAGATCGGATCATGCTGGTGGATGACTCTAACGAGGACTGGTGGAAGGGCAAGATC
GGCGACCGGGTTGGCTTCTTCCCAGCTAATTTTGTGCAACGGGTGAGGCCAGGCGAGAATGTTTGGCGCTGCTGCCAACCCTTCTCCGGG
AACAAGGAACAGGGTTACATGAGCCTCAAGGAGAACCAGATCTGCGTGGGCGTGGGCAGAAGCAAGGATGCTGACGGCTTCATCCGCGTC
AGCAGTGGCAAGAAGCGGGGCCTGGTGCCAGTCGACGCCCTGACTGAGATCTGAGAGGAGCCAAGGGAACCCAGATGACACCCTTGCCCA
TGCCTGGACCTTGCTTCTGGCCAGGGAGGGGATCAGGCCCCCTTGTCCACTCCATACCCTTCCTCCCTCTGTCCCTCTCCTAGGTGCCAC
TTACCGTGGCTTAGGAGCCTTTTGTACTGGGGAAGATTTTATTTCTTGGGTGGGGTGCCCTGAGTGGGTTGATCCTCTGGGACTTGGCGG
GGATGGGGTGGGGTGGGAGGGAATGAGGAAGCTACAGGTAGGTCCACCCAACGCCCAGGCACCCCAGTCTACTTGCTGGGCTGAGTCCAG
CCCTGGGGAAGATTCCTGGGGAATTTATTTGCTGCTTCTCCCAGCCTTCCCCTGCCCACACCACCTGCGCATGCCTGGCACACCCCTCTC
CCCACAGAGCCTCTGCTTGGGTCTATGTGTGTGTGACCGTGCATCTGCTCCTTTGCAAGTGGGGTCTTGGGAGCAGGCCTTTTTGTGTCC
TCGGCCCTCCACCCTTGGTGGGGAGGGGACCCAGGACCATAGGAAGGTCCTGAGTCCACCTCCTGGTCTCCACCTCTGTCATTCCGTCAA
TTCTCAGGAAAGTTTTGCAGGAATCTCTCCCGTTACTTGAAACCTGGGCGGACAGATGAGGGGAAGGCTGAGGTCCCTGGAAGGTGTAAC
AAATCAGAGACTATCTGTTCAAGTAGAAAACCCAAGAGCTGGCCAGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGA
GGTGGGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAGTACGAAACTTAGCCA
GGCATGATGGGGGTCTGCCTGTAATGCCAGCTACTCCAGAGGCTGAGGCAAGAGAATCACTTGAACCCGGGAGGCGGAGGTTTCAGTGAG
CCGAGATTGCACCATTGCACCCCAGCCTGGGCAACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAGAAAGAAAGAAAAGGAAACCCAAG
AGCTGCCTGGACACACGGAAACCCAACTGAGAACAAAATCCTGGCCCGTGCTTGGTCAAAGCAAACCCATTTCACTGTCAGGACCCCCGG
TCACACAGGAACCACCCGCCAGGGGAGCCTGTGACTGTCAGTTCCTGTCCCAGGCTTTGCCCGGCCGCCCCAGGAACCCAACCCTCTGGG
CTGACCTTTCTCCTGCTTCTCTCCAGGCTCTGCAGGGGACAGGGCAGGTGCTGCAGGAGCCCCTTTGCTGGCTTTATCTGCTCCCTTGTT
CTGGACACAGAGCCCTGGGAAAAAGAGGGGGTGGAAGACAGACAAGGAAGGTGGAATGTTCTGTTTTGGCCACCAGGAAATGGGGTGGGG
TGGGCATACACAGAGAGGACCCCTCTCTTAATACAGCTGCTTTTCTCGGTGCCAACCTCCCTCCCCCAAGCTCAGATCCTCCTCTTATGC
CCTTGATTGTGCCAGCCCATGCCACCCCCATCCTGGGCACAGTTACACCCTCCCATGCAGTGGGAGAAACACAGACCCTCGTACCCAAAG
GCCCCTGCCCCACTTCTCCCCCACAAAGCGGGGTCTCAAGCCACACTGCCCTGTTTGCTGCCATGAGGCCCCCCCCCCCAGCAATATCCC
AGGGGCGGGCCCAATGCCCACTGTACATGAGGCTGCATGATGGGTCTGGGGCCTTGCTGATTCCCCAGACCCCTAATTAAATGTTTCTTG

>In-frame_ENST00000360679_ENST00000333461_XX000005_ACACA_chr17_35479453_-_STAC2_chr17_37374428_length(amino acids)=2378AA_start in transcript=297_stop in transcript=7433
MTEARQKAQYLLSSWVLSSCNRRRNCGLCLQGRNLKKKLPFFSHLDMEGSPEENKEMRYYMLQRSSMSGLHLVKQGRDRKKIDSQRDFTV
ASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVEL
ILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVP
QELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAIS
LFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQL
QIAMGIPLYRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEF
ADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADV
SLRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVD
RYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVLAKMQLDN
PSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPP
NVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQ
NGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPS
YELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQF
MLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPPQSPTFPEAGHT
SLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVDHGIRRLTFLVAQKDFRKQVNYEVDRRFHREFPKFFTFRARD
KFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLE
AMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDI
SLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDML
TYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGA
RIGLAEEIRHMFHVAWVDPEDPYKGYRYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYN
EIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYM
PKSVHSSVPLLNSKDPIDRIIEFVPTKTPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRT
VELSIPADPANLDSEAKLQRFKRSLSLKTILRSKSLENFFLRSGSELKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLA
ALKPVRLHSFQEHVFKRASPCELCHQLIVGNSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPLLVHEPPPVCATSKESP
PTGDSGKVDPVYETLRYGTSLALMNRSSFSSTSESPTRSLSERDELTEDGEGSIRSSEEGPGDSASPVFTAPAESEGPGPEEKSPGQQLP
KATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVRPGENVWRCCQPFSGNKEQGYMSL

--------------------------------------------------------------
>In-frame_ENST00000361253_ENST00000333461_XX000005_ACACA_chr17_35479453_-_STAC2_chr17_37374428_length(transcript)=3625nt_BP=723nt
AGAAATTCGCCATATGTTTCATGTGGCCTGGGTAGATCCTGAGGATCCTTACAAGGGATACAGGTATTTATATCTGACTCCTCAAGATTA
TAAGAGAGTCAGTGCTCTCAACTCTGTCCATTGTGAACACGTGGAAGATGAAGGAGAATCCAGGTGACGTGCCGGGCCATTGGGATTGGG
GCTTACCTTGTCCGGCTGGGACAGAGAACCATCCAGGTTGAGAATTCTCACTTAATTCTAACAGGAGCTGGAGCCCTCAACAAAGTCCTC
GGGCGGGAAGTGTACACCTCCAATAACCAGCTGGGGGGCATCCAGATTATGCACAACAATGGGGTGACCCACTGCACTGTGTGTGATGAC
TTTGAAGGGGTTTTCACTGTCCTGCACTGGCTGTCTTACATGCCCAAGAGCGTGCACAGTTCAGTTCCTCTTCTGAACTCAAAGGATCCT
ATAGACAGAATCATCGAGTTTGTTCCCACAAAGACCCCATACGATCCTCGATGGATGCTAGCAGGCCGTCCTCACCCAACCCAAAAAGGT
CAGTGGTTGAGTGGCTTTTTTGACTATGGATCTTTCTCAGAGATTATGCAGCCCTGGGCACAGACTGTGGTGGTTGGTAGAGCCAGGCTA
GGAGGAATACCTGTGGGAGTTGTTGCTGTAGAAACCCGAACAGTAGAACTAAGTATCCCAGCTGATCCAGCAAACCTGGATTCTGAAGCC
AAGCTCCAGCGATTCAAGCGCTCCCTCTCCCTCAAGACCATCCTCCGAAGTAAGAGCTTGGAGAACTTCTTCCTTCGCTCGGGCTCTGAG
CTCAAGTGCCCCACCGAGGTGCTGCTGACGCCCCCAACCCCACTGCCCCCTCCCTCCCCACCACCCACAGCCTCGGACAGGGGCCTGGCT
ACCCCATCCCCCTCCCCATGCCCAGTCCCACGCCCCCTGGCAGCGCTCAAACCAGTGAGGCTGCACAGCTTCCAGGAACATGTCTTCAAG
CGAGCTAGCCCTTGTGAGCTGTGCCACCAGCTCATCGTAGGAAACTCCAAACAGGGCTTGCGATGTAAGATGTGCAAAGTCAGCGTCCAC
CTCTGGTGCTCTGAGGAGATCTCCCACCAGCAATGCCCAGGCAAGACGTCCACCTCCTTCCGCCGCAACTTCAGTTCCCCTCTCCTGGTG
CATGAGCCGCCACCAGTCTGTGCCACAAGCAAAGAGTCCCCACCCACTGGGGACAGTGGGAAGGTGGACCCTGTCTACGAGACCCTGCGC
TATGGCACCTCCCTGGCACTGATGAACCGCTCCAGTTTCAGCAGCACCTCTGAGTCCCCGACAAGGAGCCTGAGTGAGCGGGATGAGCTG
ACCGAGGATGGGGAAGGCAGCATCCGCAGCTCTGAGGAGGGGCCTGGTGACAGTGCATCTCCAGTATTCACAGCCCCAGCAGAGAGTGAA
GGGCCAGGACCAGAGGAGAAGAGTCCTGGACAGCAGCTCCCCAAAGCCACCCTGCGGAAGGATGTGGGGCCCATGTACTCCTACGTTGCA
CTCTACAAGTTTCTGCCCCAGGAGAACAATGATCTGGCTCTGCAGCCTGGAGATCGGATCATGCTGGTGGATGACTCTAACGAGGACTGG
TGGAAGGGCAAGATCGGCGACCGGGTTGGCTTCTTCCCAGCTAATTTTGTGCAACGGGTGAGGCCAGGCGAGAATGTTTGGCGCTGCTGC
CAACCCTTCTCCGGGAACAAGGAACAGGGTTACATGAGCCTCAAGGAGAACCAGATCTGCGTGGGCGTGGGCAGAAGCAAGGATGCTGAC
GGCTTCATCCGCGTCAGCAGTGGCAAGAAGCGGGGCCTGGTGCCAGTCGACGCCCTGACTGAGATCTGAGAGGAGCCAAGGGAACCCAGA
TGACACCCTTGCCCATGCCTGGACCTTGCTTCTGGCCAGGGAGGGGATCAGGCCCCCTTGTCCACTCCATACCCTTCCTCCCTCTGTCCC
TCTCCTAGGTGCCACTTACCGTGGCTTAGGAGCCTTTTGTACTGGGGAAGATTTTATTTCTTGGGTGGGGTGCCCTGAGTGGGTTGATCC
TCTGGGACTTGGCGGGGATGGGGTGGGGTGGGAGGGAATGAGGAAGCTACAGGTAGGTCCACCCAACGCCCAGGCACCCCAGTCTACTTG
CTGGGCTGAGTCCAGCCCTGGGGAAGATTCCTGGGGAATTTATTTGCTGCTTCTCCCAGCCTTCCCCTGCCCACACCACCTGCGCATGCC
TGGCACACCCCTCTCCCCACAGAGCCTCTGCTTGGGTCTATGTGTGTGTGACCGTGCATCTGCTCCTTTGCAAGTGGGGTCTTGGGAGCA
GGCCTTTTTGTGTCCTCGGCCCTCCACCCTTGGTGGGGAGGGGACCCAGGACCATAGGAAGGTCCTGAGTCCACCTCCTGGTCTCCACCT
CTGTCATTCCGTCAATTCTCAGGAAAGTTTTGCAGGAATCTCTCCCGTTACTTGAAACCTGGGCGGACAGATGAGGGGAAGGCTGAGGTC
CCTGGAAGGTGTAACAAATCAGAGACTATCTGTTCAAGTAGAAAACCCAAGAGCTGGCCAGGTGTGGTGGCTCATGCCTGTAATCCCAGC
ACTTTGGGAGGCTGAGGTGGGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAG
TACGAAACTTAGCCAGGCATGATGGGGGTCTGCCTGTAATGCCAGCTACTCCAGAGGCTGAGGCAAGAGAATCACTTGAACCCGGGAGGC
GGAGGTTTCAGTGAGCCGAGATTGCACCATTGCACCCCAGCCTGGGCAACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAGAAAGAAAG
AAAAGGAAACCCAAGAGCTGCCTGGACACACGGAAACCCAACTGAGAACAAAATCCTGGCCCGTGCTTGGTCAAAGCAAACCCATTTCAC
TGTCAGGACCCCCGGTCACACAGGAACCACCCGCCAGGGGAGCCTGTGACTGTCAGTTCCTGTCCCAGGCTTTGCCCGGCCGCCCCAGGA
ACCCAACCCTCTGGGCTGACCTTTCTCCTGCTTCTCTCCAGGCTCTGCAGGGGACAGGGCAGGTGCTGCAGGAGCCCCTTTGCTGGCTTT
ATCTGCTCCCTTGTTCTGGACACAGAGCCCTGGGAAAAAGAGGGGGTGGAAGACAGACAAGGAAGGTGGAATGTTCTGTTTTGGCCACCA
GGAAATGGGGTGGGGTGGGCATACACAGAGAGGACCCCTCTCTTAATACAGCTGCTTTTCTCGGTGCCAACCTCCCTCCCCCAAGCTCAG
ATCCTCCTCTTATGCCCTTGATTGTGCCAGCCCATGCCACCCCCATCCTGGGCACAGTTACACCCTCCCATGCAGTGGGAGAAACACAGA
CCCTCGTACCCAAAGGCCCCTGCCCCACTTCTCCCCCACAAAGCGGGGTCTCAAGCCACACTGCCCTGTTTGCTGCCATGAGGCCCCCCC
CCCCAGCAATATCCCAGGGGCGGGCCCAATGCCCACTGTACATGAGGCTGCATGATGGGTCTGGGGCCTTGCTGATTCCCCAGACCCCTA

>In-frame_ENST00000361253_ENST00000333461_XX000005_ACACA_chr17_35479453_-_STAC2_chr17_37374428_length(amino acids)=557AA_start in transcript=195_stop in transcript=1868
MGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRII
EFVPTKTPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKLQRF
KRSLSLKTILRSKSLENFFLRSGSELKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPVRLHSFQEHVFKRASPC
ELCHQLIVGNSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSL
ALMNRSSFSSTSESPTRSLSERDELTEDGEGSIRSSEEGPGDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVALYKFL
PQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRV

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Fusion Gene PPI Analysis for ACACA-STAC2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ACACA-STAC2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneACACAQ13085DB00121BiotinCofactorSmall moleculeApproved|Investigational|Nutraceutical
HgeneACACAQ13085DB00121BiotinCofactorSmall moleculeApproved|Investigational|Nutraceutical
HgeneACACAQ13085DB00121BiotinCofactorSmall moleculeApproved|Investigational|Nutraceutical
HgeneACACAQ13085DB00121BiotinCofactorSmall moleculeApproved|Investigational|Nutraceutical

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Related Diseases for ACACA-STAC2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneACACAC0018801Heart failure1CTD_human
HgeneACACAC0018802Congestive heart failure1CTD_human
HgeneACACAC0023212Left-Sided Heart Failure1CTD_human
HgeneACACAC0235527Heart Failure, Right-Sided1CTD_human
HgeneACACAC1959583Myocardial Failure1CTD_human
HgeneACACAC1961112Heart Decompensation1CTD_human
HgeneACACAC2239176Liver carcinoma1CTD_human