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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CD44-FAM120A (FusionGDB2 ID:14559)

Fusion Gene Summary for CD44-FAM120A

check button Fusion gene summary
Fusion gene informationFusion gene name: CD44-FAM120A
Fusion gene ID: 14559
HgeneTgene
Gene symbol

CD44

FAM120A

Gene ID

960

23196

Gene nameCD44 molecule (Indian blood group)family with sequence similarity 120A
SynonymsCDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1C9orf10|HBVPTPAP|OSSA
Cytomap

11p13

9q22.31

Type of geneprotein-codingprotein-coding
DescriptionCD44 antigenGP90 lymphocyte homing/adhesion receptorHermes antigenIndian blood group antigencell surface glycoprotein CD44chondroitin sulfate proteoglycan 8epicanextracellular matrix receptor IIIhematopoietic cell E- and L-selectin ligandheparan constitutive coactivator of PPAR-gamma-like protein 1oxidative stess-associated Src activatoroxidative stress-associated Src activator
Modification date2020032920200320
UniProtAcc

P16070

Q5T036

Ensembl transtripts involved in fusion geneENST00000263398, ENST00000526025, 
ENST00000449691, ENST00000360158, 
ENST00000415148, ENST00000437706, 
ENST00000433354, ENST00000428726, 
ENST00000526669, ENST00000433892, 
ENST00000278386, ENST00000434472, 
ENST00000352818, ENST00000528922, 
ENST00000277165, ENST00000375389, 
ENST00000340893, ENST00000333936, 
ENST00000475933, 
Fusion gene scores* DoF score24 X 25 X 12=720017 X 12 X 5=1020
# samples 3618
** MAII scorelog2(36/7200*10)=-4.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/1020*10)=-2.50250034052918
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CD44 [Title/Abstract] AND FAM120A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCD44(35227790)-FAM120A(96305504), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCD44

GO:0007155

cell adhesion

19703720

HgeneCD44

GO:0016477

cell migration

22726066

HgeneCD44

GO:0030214

hyaluronan catabolic process

17170110

HgeneCD44

GO:0033138

positive regulation of peptidyl-serine phosphorylation

17045821

HgeneCD44

GO:0042110

T cell activation

7528188

HgeneCD44

GO:0043518

negative regulation of DNA damage response, signal transduction by p53 class mediator

17045821

HgeneCD44

GO:0044344

cellular response to fibroblast growth factor stimulus

19577615

HgeneCD44

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

17045821

HgeneCD44

GO:0070374

positive regulation of ERK1 and ERK2 cascade

17045821

HgeneCD44

GO:1902166

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

17045821


check buttonFusion gene breakpoints across CD44 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across FAM120A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8080-01ACD44chr11

35227790

+FAM120Achr9

96305504

+


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Fusion Gene ORF analysis for CD44-FAM120A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000263398ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000263398ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000263398ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000263398ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000263398ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-3CDSENST00000526025ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000526025ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000526025ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000526025ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000526025ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
In-frameENST00000449691ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000449691ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000449691ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000449691ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000449691ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-3CDSENST00000360158ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000360158ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000360158ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000360158ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000360158ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
In-frameENST00000415148ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000415148ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000415148ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000415148ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000415148ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
In-frameENST00000437706ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000437706ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000437706ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000437706ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000437706ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
In-frameENST00000433354ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000433354ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000433354ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000433354ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000433354ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
In-frameENST00000428726ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000428726ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000428726ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000428726ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
5CDS-intronENST00000428726ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-3CDSENST00000526669ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000526669ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000526669ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000526669ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000526669ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-3CDSENST00000433892ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000433892ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000433892ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000433892ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000433892ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-3CDSENST00000278386ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000278386ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000278386ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000278386ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000278386ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-3CDSENST00000434472ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000434472ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000434472ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000434472ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000434472ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-3CDSENST00000352818ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000352818ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000352818ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000352818ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000352818ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-3CDSENST00000528922ENST00000277165CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000528922ENST00000375389CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000528922ENST00000340893CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000528922ENST00000333936CD44chr11

35227790

+FAM120Achr9

96305504

+
intron-intronENST00000528922ENST00000475933CD44chr11

35227790

+FAM120Achr9

96305504

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000449691CD44chr1135227790+ENST00000277165FAM120Achr996305504+4434141952866953
ENST00000415148CD44chr1135227790+ENST00000277165FAM120Achr996305504+4434141952866953
ENST00000437706CD44chr1135227790+ENST00000277165FAM120Achr996305504+4563154852995996
ENST00000433354CD44chr1135227790+ENST00000277165FAM120Achr996305504+4566155152998997
ENST00000428726CD44chr1135227790+ENST00000277165FAM120Achr996305504+45521537152984989

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000449691ENST00000277165CD44chr1135227790+FAM120Achr996305504+0.0008294850.99917054
ENST00000415148ENST00000277165CD44chr1135227790+FAM120Achr996305504+0.0008911310.99910885
ENST00000437706ENST00000277165CD44chr1135227790+FAM120Achr996305504+0.0006919120.9993081
ENST00000433354ENST00000277165CD44chr1135227790+FAM120Achr996305504+0.0006890990.99931085
ENST00000428726ENST00000277165CD44chr1135227790+FAM120Achr996305504+0.0006739710.9993261

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Fusion Genomic Features for CD44-FAM120A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CD44chr1135227790+FAM120Achr996305503+3.08E-050.99996924
CD44chr1135227790+FAM120Achr996305503+3.08E-050.99996924

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CD44-FAM120A


check button Go to

FGviewer for the breakpoints of chr11:35227790-chr9:96305504

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CD44

P16070

FAM120A

Q5T036

FUNCTION: Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment (PubMed:16541107, PubMed:19703720, PubMed:22726066). Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection (PubMed:7528188). Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases (PubMed:18757307, PubMed:23589287). Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion (PubMed:15123640). {ECO:0000269|PubMed:15123640, ECO:0000269|PubMed:16541107, ECO:0000269|PubMed:18757307, ECO:0000269|PubMed:19703720, ECO:0000269|PubMed:22726066, ECO:0000269|PubMed:23589287, ECO:0000269|PubMed:7528188}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCD44chr11:35227790chr9:96305504ENST00000415148+1017150_158428.3333333333333700.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneCD44chr11:35227790chr9:96305504ENST00000428726+1118150_158471.3333333333333743.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneCD44chr11:35227790chr9:96305504ENST00000437706+1117150_158471.3333333333333675.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneCD44chr11:35227790chr9:96305504ENST00000449691+1017150_158428.3333333333333700.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneCD44chr11:35227790chr9:96305504ENST00000415148+101732_120428.3333333333333700.0DomainLink
HgeneCD44chr11:35227790chr9:96305504ENST00000428726+111832_120471.3333333333333743.0DomainLink
HgeneCD44chr11:35227790chr9:96305504ENST00000437706+111732_120471.3333333333333675.0DomainLink
HgeneCD44chr11:35227790chr9:96305504ENST00000449691+101732_120428.3333333333333700.0DomainLink
TgeneFAM120Achr11:35227790chr9:96305504ENST00000277165918829_1118636.33333333333341119.0RegionNote=RNA binding
TgeneFAM120Achr11:35227790chr9:96305504ENST000003339361019829_1118664.33333333333341147.0RegionNote=RNA binding
TgeneFAM120Achr11:35227790chr9:96305504ENST00000340893917829_1118636.33333333333341073.0RegionNote=RNA binding
TgeneFAM120Achr11:35227790chr9:96305504ENST0000037538909829_11180629.0RegionNote=RNA binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCD44chr11:35227790chr9:96305504ENST00000263398+19150_1580362.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneCD44chr11:35227790chr9:96305504ENST00000278386+14150_1580140.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneCD44chr11:35227790chr9:96305504ENST00000352818+18150_1580.0341.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneCD44chr11:35227790chr9:96305504ENST00000360158+110150_1580397.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneCD44chr11:35227790chr9:96305504ENST00000433892+112150_1580494.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneCD44chr11:35227790chr9:96305504ENST00000434472+110150_1580430.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneCD44chr11:35227790chr9:96305504ENST00000263398+1932_1200362.0DomainLink
HgeneCD44chr11:35227790chr9:96305504ENST00000278386+1432_1200140.0DomainLink
HgeneCD44chr11:35227790chr9:96305504ENST00000352818+1832_1200.0341.0DomainLink
HgeneCD44chr11:35227790chr9:96305504ENST00000360158+11032_1200397.0DomainLink
HgeneCD44chr11:35227790chr9:96305504ENST00000433892+11232_1200494.0DomainLink
HgeneCD44chr11:35227790chr9:96305504ENST00000434472+11032_1200430.0DomainLink
HgeneCD44chr11:35227790chr9:96305504ENST00000263398+19224_6490362.0RegionNote=Stem
HgeneCD44chr11:35227790chr9:96305504ENST00000278386+14224_6490140.0RegionNote=Stem
HgeneCD44chr11:35227790chr9:96305504ENST00000352818+18224_6490.0341.0RegionNote=Stem
HgeneCD44chr11:35227790chr9:96305504ENST00000360158+110224_6490397.0RegionNote=Stem
HgeneCD44chr11:35227790chr9:96305504ENST00000415148+1017224_649428.3333333333333700.0RegionNote=Stem
HgeneCD44chr11:35227790chr9:96305504ENST00000428726+1118224_649471.3333333333333743.0RegionNote=Stem
HgeneCD44chr11:35227790chr9:96305504ENST00000433892+112224_6490494.0RegionNote=Stem
HgeneCD44chr11:35227790chr9:96305504ENST00000434472+110224_6490430.0RegionNote=Stem
HgeneCD44chr11:35227790chr9:96305504ENST00000437706+1117224_649471.3333333333333675.0RegionNote=Stem
HgeneCD44chr11:35227790chr9:96305504ENST00000449691+1017224_649428.3333333333333700.0RegionNote=Stem
HgeneCD44chr11:35227790chr9:96305504ENST00000263398+1921_6490362.0Topological domainExtracellular
HgeneCD44chr11:35227790chr9:96305504ENST00000263398+19671_7420362.0Topological domainCytoplasmic
HgeneCD44chr11:35227790chr9:96305504ENST00000278386+1421_6490140.0Topological domainExtracellular
HgeneCD44chr11:35227790chr9:96305504ENST00000278386+14671_7420140.0Topological domainCytoplasmic
HgeneCD44chr11:35227790chr9:96305504ENST00000352818+1821_6490.0341.0Topological domainExtracellular
HgeneCD44chr11:35227790chr9:96305504ENST00000352818+18671_7420.0341.0Topological domainCytoplasmic
HgeneCD44chr11:35227790chr9:96305504ENST00000360158+11021_6490397.0Topological domainExtracellular
HgeneCD44chr11:35227790chr9:96305504ENST00000360158+110671_7420397.0Topological domainCytoplasmic
HgeneCD44chr11:35227790chr9:96305504ENST00000415148+101721_649428.3333333333333700.0Topological domainExtracellular
HgeneCD44chr11:35227790chr9:96305504ENST00000415148+1017671_742428.3333333333333700.0Topological domainCytoplasmic
HgeneCD44chr11:35227790chr9:96305504ENST00000428726+111821_649471.3333333333333743.0Topological domainExtracellular
HgeneCD44chr11:35227790chr9:96305504ENST00000428726+1118671_742471.3333333333333743.0Topological domainCytoplasmic
HgeneCD44chr11:35227790chr9:96305504ENST00000433892+11221_6490494.0Topological domainExtracellular
HgeneCD44chr11:35227790chr9:96305504ENST00000433892+112671_7420494.0Topological domainCytoplasmic
HgeneCD44chr11:35227790chr9:96305504ENST00000434472+11021_6490430.0Topological domainExtracellular
HgeneCD44chr11:35227790chr9:96305504ENST00000434472+110671_7420430.0Topological domainCytoplasmic
HgeneCD44chr11:35227790chr9:96305504ENST00000437706+111721_649471.3333333333333675.0Topological domainExtracellular
HgeneCD44chr11:35227790chr9:96305504ENST00000437706+1117671_742471.3333333333333675.0Topological domainCytoplasmic
HgeneCD44chr11:35227790chr9:96305504ENST00000449691+101721_649428.3333333333333700.0Topological domainExtracellular
HgeneCD44chr11:35227790chr9:96305504ENST00000449691+1017671_742428.3333333333333700.0Topological domainCytoplasmic
HgeneCD44chr11:35227790chr9:96305504ENST00000263398+19650_6700362.0TransmembraneHelical
HgeneCD44chr11:35227790chr9:96305504ENST00000278386+14650_6700140.0TransmembraneHelical
HgeneCD44chr11:35227790chr9:96305504ENST00000352818+18650_6700.0341.0TransmembraneHelical
HgeneCD44chr11:35227790chr9:96305504ENST00000360158+110650_6700397.0TransmembraneHelical
HgeneCD44chr11:35227790chr9:96305504ENST00000415148+1017650_670428.3333333333333700.0TransmembraneHelical
HgeneCD44chr11:35227790chr9:96305504ENST00000428726+1118650_670471.3333333333333743.0TransmembraneHelical
HgeneCD44chr11:35227790chr9:96305504ENST00000433892+112650_6700494.0TransmembraneHelical
HgeneCD44chr11:35227790chr9:96305504ENST00000434472+110650_6700430.0TransmembraneHelical
HgeneCD44chr11:35227790chr9:96305504ENST00000437706+1117650_670471.3333333333333675.0TransmembraneHelical
HgeneCD44chr11:35227790chr9:96305504ENST00000449691+1017650_670428.3333333333333700.0TransmembraneHelical


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Fusion Gene Sequence for CD44-FAM120A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000449691_ENST00000277165_TCGA-BR-8080-01A_CD44_chr11_35227790_+_FAM120A_chr9_96305504_length(transcript)=4434nt_BP=1419nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGATTTGAATATAACCTGCCGCTTTGCAGGTGTATTCCACGTGGAGAAAAATGGTCGCTACAGCATCTCTC
GGACGGAGGCCGCTGACCTCTGCAAGGCTTTCAATAGCACCTTGCCCACAATGGCCCAGATGGAGAAAGCTCTGAGCATCGGATTTGAGA
CCTGCAGGTATGGGTTCATAGAAGGGCACGTGGTGATTCCCCGGATCCACCCCAACTCCATCTGTGCAGCAAACAACACAGGGGTGTACA
TCCTCACATCCAACACCTCCCAGTATGACACATATTGCTTCAATGCTTCAGCTCCACCTGAAGAAGATTGTACATCAGTCACAGACCTGC
CCAATGCCTTTGATGGACCAATTACCATAACTATTGTTAACCGTGATGGCACCCGCTATGTCCAGAAAGGAGAATACAGAACGAATCCTG
AAGACATCTACCCCAGCAACCCTACTGATGATGACGTGAGCAGCGGCTCCTCCAGTGAAAGGAGCAGCACTTCAGGAGGTTACATCTTTT
ACACCTTTTCTACTGTACACCCCATCCCAGACGAAGACAGTCCCTGGATCACCGACAGCACAGACAGAATCCCTGCTACCACTTTGATGA
GCACTAGTGCTACAGCAACTGAGACAGCAACCAAGAGGCAAGAAACCTGGGATTGGTTTTCATGGTTGTTTCTACCATCAGAGTCAAAGA
ATCATCTTCACACAACAACACAAATGGCTGGTACGTCTTCAAATACCATCTCAGCAGGCTGGGAGCCAAATGAAGAAAATGAAGATGAAA
GAGACAGACACCTCAGTTTTTCTGGATCAGGCATTGATGATGATGAAGATTTTATCTCCAGCACCATTTCAACCACACCACGGGCTTTTG
ACCACACAAAACAGAACCAGGACTGGACCCAGTGGAACCCAAGCCATTCAAATCCGGAAGTGCTACTTCAGACAACCACAAGGATGACTG
ATGTAGACAGAAATGGCACCACTGCTTATGAAGGAAACTGGAACCCAGAAGCACACCCTCCCCTCATTCACCATGAGCATCATGAGGAAG
AAGAGACCCCACATTCTACAAGCACAACAGCCTCAGCTCATACCAGCCATCCAATGCAAGGAAGGACAACACCAAGCCCAGAGGACAGTT
CCTGGACTGATTTCTTCAACCCAATCTCACACCCCATGGGACGAGGTCATCAAGCAGGAAGAAGGATGGTTTCACCAGTGATCATTAAAG
AATGGGCAGCTTACAAAGGAAAGTCTCCTCAAACCCCGGAACTGGTTGAAGCTCTTGCCTTCAGGGAGTGGACCTGCCCCAACCTGAAGA
GGCTGTGGTTGGGTAAGGCGGTAGAGGACAAGAACCGCAGGATGAGGGCCTTCCTGGCCTGCATGAGGTCGGACACCCCAGCCATGCTCA
ACCCTGCCAACGTGCCCACTCACCTCATGGTGCTCTGCTGCGTCTTACGGTACATGGTGCAGTGGCCGGGAGCACGCATCCTTCGGCGTC
AGGAGCTAGATGCCTTCCTGGCTCAGGCGCTGTCCCCCAAACTCTACGAGCCTGATCAGCTCCAGGAGCTCAAGATTGAGAACCTAGATC
CCCGAGGAATTCAGCTATCAGCTCTCTTCATGAGTGGAGTAGACATGGCCTTGTTTGCAAATGATGCATGCGGACAGCCAATCCCCTGGG
AACACTGTTGTCCTTGGATGTATTTTGATGGGAAGCTCTTCCAATCCAAACTCCTCAAAGCCAGCCGGGAAAAGACCCCACTCATTGACC
TCTGTGATGGTCAGGCTGATCAGGCTGCCAAGGTAGAGAAGATGCGCCAGAGCGTCCTCGAGGGGCTCAGCTTCTCCAGGCAGAGCCACA
CGCTCCCTTTCCCGCCGCCACCTGCCCTGCCCTTCTACCCTGCCTCTGCGTACCCCCGGCACTTTGGGCCTGTCCCACCCTCTCAGGGCA
GGGGCAGAGGCTTTGCAGGCGTCTGTGGCTTTGGAGGCCCCTATGGGGAAACGGTAGCAACAGGCCCTTACCGTGCCTTCCGTGTGGCGG
CAGCATCGGGACACTGCGGAGCCTTCTCAGGCAGTGACAGCAGCAGGACTAGCAAGTCCCAGGGCGGAGTCCAACCTATACCTTCTCAGG
GAGGCAAACTAGAAATAGCTGGCACTGTGGTTGGCCATTGGGCTGGGAGCAGGCGGGGCCGTGGGGGCCGGGGGCCTTTCCCCCTGCAGG
TGGTTTCTGTCGGAGGACCAGCTAGAGGGCGTCCAAGAGGAGTTATTTCCACCCCAGTGATTAGAACATTTGGAAGAGGTGGAAGGTACT
ATGGCAGAGGTTACAAAAACCAGGCAGCAATTCAGGGCAGACCTCCTTATGCTGCTTCAGCAGAAGAAGTGGCCAAAGAACTTAAGTCAA
AATCTGGGGAATCGAAGTCCTCTGCTATGTCTTCAGACGGGTCCCTGGCTGAAAACGGAGTGATGGCCGAGGAGAAGCCGGCTCCCCAGA
TGAACGGGAGCACGGGTGACGCCAGGGCCCCCAGCCACTCTGAAAGTGCCTTGAATAATGACTCTAAAACGTGCAATACAAATCCTCATT
TAAATGCACTAAGTACAGACAGCGCTTGCCGCAGAGAAGCTGCTCTGGAGGCAGCTGTCTTAAATAAAGAAGAGTAAACTTATTTTTTAT
AGAGGGTGAAGGATGCTGGAAGGGTAAGGATTTAGGAATATCTGGAGAGAAAGAGAGCCTGCAGTTATGTACATTTTGTCCTTTCCGTAA
GAGAAAAATGAGGACTTTGGAAATTCAGATCCCTCTTTGATATCAGAGATTTAAACAACACATTTTTAGTTTTAACCAGTTGTAGTCAAA
ATGCTACAATAAAACAAAAAAGAGAAAGAAAATGAAGAGCATTTGACTCCCGCACTTAAAATGAAGTACACATAAAGTTTAAACTGGTTA
TGACAAAAGCCTTTAGTTGTGTTTCTTGAACTATAAAGAAAACAAATTTTGGCAGTCTTTAAGTATATATAGCTTAAAATATAATTTTTA
GCATTTGGCACCATATGTATGCCATTATATTTGATTTTGCATTACTGTTTCACAATGAAGCTTTCTTTAAGGCTTTGATTTTTATGATTA
TGAAAGAAATAAGGCACAACCACAGTTTTTCTTTCTTAAATTTCATCACTGTTGATGTGGTTCTTTTGTGTTAAAAAAAAAAAGTGCAAC
TATCAAAACTAAAAAATTATAGAGTAATATTGCCGTTCTGCTGATTTTAAATATACAATACATCATACATACTTTACAAGCAAGTTAAAT
GGAGATAAAGTTGAAATCATAGAAGATGCAAATGACCTTTCAAAATCAACACAATGTGTTCTGAAACTTTCGTGACTAATACCATGCATC
TGTGATCAATGAACTATGTGGTTTTGAATCGGATGTAGACCATTAGTACTACTACTTGAGCTAAACTTCTGCATGGTTCATAATTTTTAA
AGTGTGTAGTTAATATGCATGTTATCGTCCTTTCTTCCATTCTTAACAGTATGTGCCCATTTGCAAAACAAAAATGCTAATAATCAGTAA
TAGTCCTATAAAAGATGTTAACTCTGTTTAGTCATTGACTGATCTTGCTCTAACCTTAAAATTTTGTGATTATTGACCTCTGTTGCATTT
ATTCTAAAGCCCCCCAAAAATTATCTAGCCGTTTCGAATATCAACATTACCCTGGTGTATTCACTGCTGTATGCATTATTGTTCTTTGTT
GCTGTTTTATGCCTTCATATTAGCAAATATGAAATTCTGTGAAAAAAAACCCTTTGATCTTAAAAAAAAAAAAACCACCCCCCCCTTCTG
TAGCAGGAAACAAATTGCTTGTTCTTGAGAACTTTCCCATCAAGAATTTAGTAGAAGCAGGTATACTTCTATCATTTTGATGTTTTTGTT
AATGTTTCCAAACAATGTACTTTGAAATCAGAATCACTTCTTATCGTTTTCATATACTTCTGATGCTCTTCATCACATTAGTGATCAGAA
ATGAGGTGTAATTCCCCAACCCCTGCCCGCAAGAGCTAAGTAGGATCTTACTGTAAGTTGAAGGGAGTTTTGCCCTAACTCATGGATTGT
GCAAGAATGAACTGCTGTTGGGTTTGATTGACTGTCGATGGATTGTGGTGTGGTGTATCTGAAGGCTATTGAATGCAACTTACAATGCTT

>In-frame_ENST00000449691_ENST00000277165_TCGA-BR-8080-01A_CD44_chr11_35227790_+_FAM120A_chr9_96305504_length(amino acids)=953AA_start in transcript=5_stop in transcript=2866
MPSGPQPLPGSVRHPRPVLRRPLPRAQGSSSSFRPRPPFAPDTMDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRT
EAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPN
AFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMST
SATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDH
TKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTTASAHTSHPMQGRTTPSPEDSSW
TDFFNPISHPMGRGHQAGRRMVSPVIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNP
ANVPTHLMVLCCVLRYMVQWPGARILRRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPIPWEH
CCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQADQAAKVEKMRQSVLEGLSFSRQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRG
RGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVV
SVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPYAASAEEVAKELKSKSGESKSSAMSSDGSLAENGVMAEEKPAPQMN

--------------------------------------------------------------
>In-frame_ENST00000415148_ENST00000277165_TCGA-BR-8080-01A_CD44_chr11_35227790_+_FAM120A_chr9_96305504_length(transcript)=4434nt_BP=1419nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGATTTGAATATAACCTGCCGCTTTGCAGGTGTATTCCACGTGGAGAAAAATGGTCGCTACAGCATCTCTC
GGACGGAGGCCGCTGACCTCTGCAAGGCTTTCAATAGCACCTTGCCCACAATGGCCCAGATGGAGAAAGCTCTGAGCATCGGATTTGAGA
CCTGCAGGTATGGGTTCATAGAAGGGCACGTGGTGATTCCCCGGATCCACCCCAACTCCATCTGTGCAGCAAACAACACAGGGGTGTACA
TCCTCACATCCAACACCTCCCAGTATGACACATATTGCTTCAATGCTTCAGCTCCACCTGAAGAAGATTGTACATCAGTCACAGACCTGC
CCAATGCCTTTGATGGACCAATTACCATAACTATTGTTAACCGTGATGGCACCCGCTATGTCCAGAAAGGAGAATACAGAACGAATCCTG
AAGACATCTACCCCAGCAACCCTACTGATGATGACGTGAGCAGCGGCTCCTCCAGTGAAAGGAGCAGCACTTCAGGAGGTTACATCTTTT
ACACCTTTTCTACTGTACACCCCATCCCAGACGAAGACAGTCCCTGGATCACCGACAGCACAGACAGAATCCCTGCTACCAGTACGTCTT
CAAATACCATCTCAGCAGGCTGGGAGCCAAATGAAGAAAATGAAGATGAAAGAGACAGACACCTCAGTTTTTCTGGATCAGGCATTGATG
ATGATGAAGATTTTATCTCCAGCACCATTTCAACCACACCACGGGCTTTTGACCACACAAAACAGAACCAGGACTGGACCCAGTGGAACC
CAAGCCATTCAAATCCGGAAGTGCTACTTCAGACAACCACAAGGATGACTGATGTAGACAGAAATGGCACCACTGCTTATGAAGGAAACT
GGAACCCAGAAGCACACCCTCCCCTCATTCACCATGAGCATCATGAGGAAGAAGAGACCCCACATTCTACAAGCACAATCCAGGCAACTC
CTAGTAGTACAACGGAAGAAACAGCTACCCAGAAGGAACAGTGGTTTGGCAACAGATGGCATGAGGGATATCGCCAAACACCCAAAGAAG
ACTCCCATTCGACAACAGGGACAGCTGCAGCCTCAGCTCATACCAGCCATCCAATGCAAGGAAGGACAACACCAAGCCCAGAGGACAGTT
CCTGGACTGATTTCTTCAACCCAATCTCACACCCCATGGGACGAGGTCATCAAGCAGGAAGAAGGATGGTTTCACCAGTGATCATTAAAG
AATGGGCAGCTTACAAAGGAAAGTCTCCTCAAACCCCGGAACTGGTTGAAGCTCTTGCCTTCAGGGAGTGGACCTGCCCCAACCTGAAGA
GGCTGTGGTTGGGTAAGGCGGTAGAGGACAAGAACCGCAGGATGAGGGCCTTCCTGGCCTGCATGAGGTCGGACACCCCAGCCATGCTCA
ACCCTGCCAACGTGCCCACTCACCTCATGGTGCTCTGCTGCGTCTTACGGTACATGGTGCAGTGGCCGGGAGCACGCATCCTTCGGCGTC
AGGAGCTAGATGCCTTCCTGGCTCAGGCGCTGTCCCCCAAACTCTACGAGCCTGATCAGCTCCAGGAGCTCAAGATTGAGAACCTAGATC
CCCGAGGAATTCAGCTATCAGCTCTCTTCATGAGTGGAGTAGACATGGCCTTGTTTGCAAATGATGCATGCGGACAGCCAATCCCCTGGG
AACACTGTTGTCCTTGGATGTATTTTGATGGGAAGCTCTTCCAATCCAAACTCCTCAAAGCCAGCCGGGAAAAGACCCCACTCATTGACC
TCTGTGATGGTCAGGCTGATCAGGCTGCCAAGGTAGAGAAGATGCGCCAGAGCGTCCTCGAGGGGCTCAGCTTCTCCAGGCAGAGCCACA
CGCTCCCTTTCCCGCCGCCACCTGCCCTGCCCTTCTACCCTGCCTCTGCGTACCCCCGGCACTTTGGGCCTGTCCCACCCTCTCAGGGCA
GGGGCAGAGGCTTTGCAGGCGTCTGTGGCTTTGGAGGCCCCTATGGGGAAACGGTAGCAACAGGCCCTTACCGTGCCTTCCGTGTGGCGG
CAGCATCGGGACACTGCGGAGCCTTCTCAGGCAGTGACAGCAGCAGGACTAGCAAGTCCCAGGGCGGAGTCCAACCTATACCTTCTCAGG
GAGGCAAACTAGAAATAGCTGGCACTGTGGTTGGCCATTGGGCTGGGAGCAGGCGGGGCCGTGGGGGCCGGGGGCCTTTCCCCCTGCAGG
TGGTTTCTGTCGGAGGACCAGCTAGAGGGCGTCCAAGAGGAGTTATTTCCACCCCAGTGATTAGAACATTTGGAAGAGGTGGAAGGTACT
ATGGCAGAGGTTACAAAAACCAGGCAGCAATTCAGGGCAGACCTCCTTATGCTGCTTCAGCAGAAGAAGTGGCCAAAGAACTTAAGTCAA
AATCTGGGGAATCGAAGTCCTCTGCTATGTCTTCAGACGGGTCCCTGGCTGAAAACGGAGTGATGGCCGAGGAGAAGCCGGCTCCCCAGA
TGAACGGGAGCACGGGTGACGCCAGGGCCCCCAGCCACTCTGAAAGTGCCTTGAATAATGACTCTAAAACGTGCAATACAAATCCTCATT
TAAATGCACTAAGTACAGACAGCGCTTGCCGCAGAGAAGCTGCTCTGGAGGCAGCTGTCTTAAATAAAGAAGAGTAAACTTATTTTTTAT
AGAGGGTGAAGGATGCTGGAAGGGTAAGGATTTAGGAATATCTGGAGAGAAAGAGAGCCTGCAGTTATGTACATTTTGTCCTTTCCGTAA
GAGAAAAATGAGGACTTTGGAAATTCAGATCCCTCTTTGATATCAGAGATTTAAACAACACATTTTTAGTTTTAACCAGTTGTAGTCAAA
ATGCTACAATAAAACAAAAAAGAGAAAGAAAATGAAGAGCATTTGACTCCCGCACTTAAAATGAAGTACACATAAAGTTTAAACTGGTTA
TGACAAAAGCCTTTAGTTGTGTTTCTTGAACTATAAAGAAAACAAATTTTGGCAGTCTTTAAGTATATATAGCTTAAAATATAATTTTTA
GCATTTGGCACCATATGTATGCCATTATATTTGATTTTGCATTACTGTTTCACAATGAAGCTTTCTTTAAGGCTTTGATTTTTATGATTA
TGAAAGAAATAAGGCACAACCACAGTTTTTCTTTCTTAAATTTCATCACTGTTGATGTGGTTCTTTTGTGTTAAAAAAAAAAAGTGCAAC
TATCAAAACTAAAAAATTATAGAGTAATATTGCCGTTCTGCTGATTTTAAATATACAATACATCATACATACTTTACAAGCAAGTTAAAT
GGAGATAAAGTTGAAATCATAGAAGATGCAAATGACCTTTCAAAATCAACACAATGTGTTCTGAAACTTTCGTGACTAATACCATGCATC
TGTGATCAATGAACTATGTGGTTTTGAATCGGATGTAGACCATTAGTACTACTACTTGAGCTAAACTTCTGCATGGTTCATAATTTTTAA
AGTGTGTAGTTAATATGCATGTTATCGTCCTTTCTTCCATTCTTAACAGTATGTGCCCATTTGCAAAACAAAAATGCTAATAATCAGTAA
TAGTCCTATAAAAGATGTTAACTCTGTTTAGTCATTGACTGATCTTGCTCTAACCTTAAAATTTTGTGATTATTGACCTCTGTTGCATTT
ATTCTAAAGCCCCCCAAAAATTATCTAGCCGTTTCGAATATCAACATTACCCTGGTGTATTCACTGCTGTATGCATTATTGTTCTTTGTT
GCTGTTTTATGCCTTCATATTAGCAAATATGAAATTCTGTGAAAAAAAACCCTTTGATCTTAAAAAAAAAAAAACCACCCCCCCCTTCTG
TAGCAGGAAACAAATTGCTTGTTCTTGAGAACTTTCCCATCAAGAATTTAGTAGAAGCAGGTATACTTCTATCATTTTGATGTTTTTGTT
AATGTTTCCAAACAATGTACTTTGAAATCAGAATCACTTCTTATCGTTTTCATATACTTCTGATGCTCTTCATCACATTAGTGATCAGAA
ATGAGGTGTAATTCCCCAACCCCTGCCCGCAAGAGCTAAGTAGGATCTTACTGTAAGTTGAAGGGAGTTTTGCCCTAACTCATGGATTGT
GCAAGAATGAACTGCTGTTGGGTTTGATTGACTGTCGATGGATTGTGGTGTGGTGTATCTGAAGGCTATTGAATGCAACTTACAATGCTT

>In-frame_ENST00000415148_ENST00000277165_TCGA-BR-8080-01A_CD44_chr11_35227790_+_FAM120A_chr9_96305504_length(amino acids)=953AA_start in transcript=5_stop in transcript=2866
MPSGPQPLPGSVRHPRPVLRRPLPRAQGSSSSFRPRPPFAPDTMDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRT
EAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPN
AFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSN
TISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN
PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSW
TDFFNPISHPMGRGHQAGRRMVSPVIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNP
ANVPTHLMVLCCVLRYMVQWPGARILRRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPIPWEH
CCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQADQAAKVEKMRQSVLEGLSFSRQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRG
RGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVV
SVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPYAASAEEVAKELKSKSGESKSSAMSSDGSLAENGVMAEEKPAPQMN

--------------------------------------------------------------
>In-frame_ENST00000437706_ENST00000277165_TCGA-BR-8080-01A_CD44_chr11_35227790_+_FAM120A_chr9_96305504_length(transcript)=4563nt_BP=1548nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGATTTGAATATAACCTGCCGCTTTGCAGGTGTATTCCACGTGGAGAAAAATGGTCGCTACAGCATCTCTC
GGACGGAGGCCGCTGACCTCTGCAAGGCTTTCAATAGCACCTTGCCCACAATGGCCCAGATGGAGAAAGCTCTGAGCATCGGATTTGAGA
CCTGCAGGTATGGGTTCATAGAAGGGCACGTGGTGATTCCCCGGATCCACCCCAACTCCATCTGTGCAGCAAACAACACAGGGGTGTACA
TCCTCACATCCAACACCTCCCAGTATGACACATATTGCTTCAATGCTTCAGCTCCACCTGAAGAAGATTGTACATCAGTCACAGACCTGC
CCAATGCCTTTGATGGACCAATTACCATAACTATTGTTAACCGTGATGGCACCCGCTATGTCCAGAAAGGAGAATACAGAACGAATCCTG
AAGACATCTACCCCAGCAACCCTACTGATGATGACGTGAGCAGCGGCTCCTCCAGTGAAAGGAGCAGCACTTCAGGAGGTTACATCTTTT
ACACCTTTTCTACTGTACACCCCATCCCAGACGAAGACAGTCCCTGGATCACCGACAGCACAGACAGAATCCCTGCTACCACTTTGATGA
GCACTAGTGCTACAGCAACTGAGACAGCAACCAAGAGGCAAGAAACCTGGGATTGGTTTTCATGGTTGTTTCTACCATCAGAGTCAAAGA
ATCATCTTCACACAACAACACAAATGGCTGGTACGTCTTCAAATACCATCTCAGCAGGCTGGGAGCCAAATGAAGAAAATGAAGATGAAA
GAGACAGACACCTCAGTTTTTCTGGATCAGGCATTGATGATGATGAAGATTTTATCTCCAGCACCATTTCAACCACACCACGGGCTTTTG
ACCACACAAAACAGAACCAGGACTGGACCCAGTGGAACCCAAGCCATTCAAATCCGGAAGTGCTACTTCAGACAACCACAAGGATGACTG
ATGTAGACAGAAATGGCACCACTGCTTATGAAGGAAACTGGAACCCAGAAGCACACCCTCCCCTCATTCACCATGAGCATCATGAGGAAG
AAGAGACCCCACATTCTACAAGCACAATCCAGGCAACTCCTAGTAGTACAACGGAAGAAACAGCTACCCAGAAGGAACAGTGGTTTGGCA
ACAGATGGCATGAGGGATATCGCCAAACACCCAAAGAAGACTCCCATTCGACAACAGGGACAGCTGCAGCCTCAGCTCATACCAGCCATC
CAATGCAAGGAAGGACAACACCAAGCCCAGAGGACAGTTCCTGGACTGATTTCTTCAACCCAATCTCACACCCCATGGGACGAGGTCATC
AAGCAGGAAGAAGGATGGTTTCACCAGTGATCATTAAAGAATGGGCAGCTTACAAAGGAAAGTCTCCTCAAACCCCGGAACTGGTTGAAG
CTCTTGCCTTCAGGGAGTGGACCTGCCCCAACCTGAAGAGGCTGTGGTTGGGTAAGGCGGTAGAGGACAAGAACCGCAGGATGAGGGCCT
TCCTGGCCTGCATGAGGTCGGACACCCCAGCCATGCTCAACCCTGCCAACGTGCCCACTCACCTCATGGTGCTCTGCTGCGTCTTACGGT
ACATGGTGCAGTGGCCGGGAGCACGCATCCTTCGGCGTCAGGAGCTAGATGCCTTCCTGGCTCAGGCGCTGTCCCCCAAACTCTACGAGC
CTGATCAGCTCCAGGAGCTCAAGATTGAGAACCTAGATCCCCGAGGAATTCAGCTATCAGCTCTCTTCATGAGTGGAGTAGACATGGCCT
TGTTTGCAAATGATGCATGCGGACAGCCAATCCCCTGGGAACACTGTTGTCCTTGGATGTATTTTGATGGGAAGCTCTTCCAATCCAAAC
TCCTCAAAGCCAGCCGGGAAAAGACCCCACTCATTGACCTCTGTGATGGTCAGGCTGATCAGGCTGCCAAGGTAGAGAAGATGCGCCAGA
GCGTCCTCGAGGGGCTCAGCTTCTCCAGGCAGAGCCACACGCTCCCTTTCCCGCCGCCACCTGCCCTGCCCTTCTACCCTGCCTCTGCGT
ACCCCCGGCACTTTGGGCCTGTCCCACCCTCTCAGGGCAGGGGCAGAGGCTTTGCAGGCGTCTGTGGCTTTGGAGGCCCCTATGGGGAAA
CGGTAGCAACAGGCCCTTACCGTGCCTTCCGTGTGGCGGCAGCATCGGGACACTGCGGAGCCTTCTCAGGCAGTGACAGCAGCAGGACTA
GCAAGTCCCAGGGCGGAGTCCAACCTATACCTTCTCAGGGAGGCAAACTAGAAATAGCTGGCACTGTGGTTGGCCATTGGGCTGGGAGCA
GGCGGGGCCGTGGGGGCCGGGGGCCTTTCCCCCTGCAGGTGGTTTCTGTCGGAGGACCAGCTAGAGGGCGTCCAAGAGGAGTTATTTCCA
CCCCAGTGATTAGAACATTTGGAAGAGGTGGAAGGTACTATGGCAGAGGTTACAAAAACCAGGCAGCAATTCAGGGCAGACCTCCTTATG
CTGCTTCAGCAGAAGAAGTGGCCAAAGAACTTAAGTCAAAATCTGGGGAATCGAAGTCCTCTGCTATGTCTTCAGACGGGTCCCTGGCTG
AAAACGGAGTGATGGCCGAGGAGAAGCCGGCTCCCCAGATGAACGGGAGCACGGGTGACGCCAGGGCCCCCAGCCACTCTGAAAGTGCCT
TGAATAATGACTCTAAAACGTGCAATACAAATCCTCATTTAAATGCACTAAGTACAGACAGCGCTTGCCGCAGAGAAGCTGCTCTGGAGG
CAGCTGTCTTAAATAAAGAAGAGTAAACTTATTTTTTATAGAGGGTGAAGGATGCTGGAAGGGTAAGGATTTAGGAATATCTGGAGAGAA
AGAGAGCCTGCAGTTATGTACATTTTGTCCTTTCCGTAAGAGAAAAATGAGGACTTTGGAAATTCAGATCCCTCTTTGATATCAGAGATT
TAAACAACACATTTTTAGTTTTAACCAGTTGTAGTCAAAATGCTACAATAAAACAAAAAAGAGAAAGAAAATGAAGAGCATTTGACTCCC
GCACTTAAAATGAAGTACACATAAAGTTTAAACTGGTTATGACAAAAGCCTTTAGTTGTGTTTCTTGAACTATAAAGAAAACAAATTTTG
GCAGTCTTTAAGTATATATAGCTTAAAATATAATTTTTAGCATTTGGCACCATATGTATGCCATTATATTTGATTTTGCATTACTGTTTC
ACAATGAAGCTTTCTTTAAGGCTTTGATTTTTATGATTATGAAAGAAATAAGGCACAACCACAGTTTTTCTTTCTTAAATTTCATCACTG
TTGATGTGGTTCTTTTGTGTTAAAAAAAAAAAGTGCAACTATCAAAACTAAAAAATTATAGAGTAATATTGCCGTTCTGCTGATTTTAAA
TATACAATACATCATACATACTTTACAAGCAAGTTAAATGGAGATAAAGTTGAAATCATAGAAGATGCAAATGACCTTTCAAAATCAACA
CAATGTGTTCTGAAACTTTCGTGACTAATACCATGCATCTGTGATCAATGAACTATGTGGTTTTGAATCGGATGTAGACCATTAGTACTA
CTACTTGAGCTAAACTTCTGCATGGTTCATAATTTTTAAAGTGTGTAGTTAATATGCATGTTATCGTCCTTTCTTCCATTCTTAACAGTA
TGTGCCCATTTGCAAAACAAAAATGCTAATAATCAGTAATAGTCCTATAAAAGATGTTAACTCTGTTTAGTCATTGACTGATCTTGCTCT
AACCTTAAAATTTTGTGATTATTGACCTCTGTTGCATTTATTCTAAAGCCCCCCAAAAATTATCTAGCCGTTTCGAATATCAACATTACC
CTGGTGTATTCACTGCTGTATGCATTATTGTTCTTTGTTGCTGTTTTATGCCTTCATATTAGCAAATATGAAATTCTGTGAAAAAAAACC
CTTTGATCTTAAAAAAAAAAAAACCACCCCCCCCTTCTGTAGCAGGAAACAAATTGCTTGTTCTTGAGAACTTTCCCATCAAGAATTTAG
TAGAAGCAGGTATACTTCTATCATTTTGATGTTTTTGTTAATGTTTCCAAACAATGTACTTTGAAATCAGAATCACTTCTTATCGTTTTC
ATATACTTCTGATGCTCTTCATCACATTAGTGATCAGAAATGAGGTGTAATTCCCCAACCCCTGCCCGCAAGAGCTAAGTAGGATCTTAC
TGTAAGTTGAAGGGAGTTTTGCCCTAACTCATGGATTGTGCAAGAATGAACTGCTGTTGGGTTTGATTGACTGTCGATGGATTGTGGTGT

>In-frame_ENST00000437706_ENST00000277165_TCGA-BR-8080-01A_CD44_chr11_35227790_+_FAM120A_chr9_96305504_length(amino acids)=996AA_start in transcript=5_stop in transcript=2995
MPSGPQPLPGSVRHPRPVLRRPLPRAQGSSSSFRPRPPFAPDTMDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRT
EAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPN
AFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMST
SATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDH
TKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNR
WHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMVSPVIIKEWAAYKGKSPQTPELVEAL
AFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPANVPTHLMVLCCVLRYMVQWPGARILRRQELDAFLAQALSPKLYEPD
QLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPIPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQADQAAKVEKMRQSV
LEGLSFSRQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRGRGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFSGSDSSRTSK
SQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPYAA
SAEEVAKELKSKSGESKSSAMSSDGSLAENGVMAEEKPAPQMNGSTGDARAPSHSESALNNDSKTCNTNPHLNALSTDSACRREAALEAA

--------------------------------------------------------------
>In-frame_ENST00000433354_ENST00000277165_TCGA-BR-8080-01A_CD44_chr11_35227790_+_FAM120A_chr9_96305504_length(transcript)=4566nt_BP=1551nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGATTTGAATATAACCTGCCGCTTTGCAGGTGTATTCCACGTGGAGAAAAATGGTCGCTACAGCATCTCTC
GGACGGAGGCCGCTGACCTCTGCAAGGCTTTCAATAGCACCTTGCCCACAATGGCCCAGATGGAGAAAGCTCTGAGCATCGGATTTGAGA
CCTGCAGGTATGGGTTCATAGAAGGGCACGTGGTGATTCCCCGGATCCACCCCAACTCCATCTGTGCAGCAAACAACACAGGGGTGTACA
TCCTCACATCCAACACCTCCCAGTATGACACATATTGCTTCAATGCTTCAGCTCCACCTGAAGAAGATTGTACATCAGTCACAGACCTGC
CCAATGCCTTTGATGGACCAATTACCATAACTATTGTTAACCGTGATGGCACCCGCTATGTCCAGAAAGGAGAATACAGAACGAATCCTG
AAGACATCTACCCCAGCAACCCTACTGATGATGACGTGAGCAGCGGCTCCTCCAGTGAAAGGAGCAGCACTTCAGGAGGTTACATCTTTT
ACACCTTTTCTACTGTACACCCCATCCCAGACGAAGACAGTCCCTGGATCACCGACAGCACAGACAGAATCCCTGCTACCACTTTGATGA
GCACTAGTGCTACAGCAACTGAGACAGCAACCAAGAGGCAAGAAACCTGGGATTGGTTTTCATGGTTGTTTCTACCATCAGAGTCAAAGA
ATCATCTTCACACAACAACACAAATGGCTGGTACGTCTTCAAATACCATCTCAGCAGGCTGGGAGCCAAATGAAGAAAATGAAGATGAAA
GAGACAGACACCTCAGTTTTTCTGGATCAGGCATTGATGATGATGAAGATTTTATCTCCAGCACCATTTCAACCACACCACGGGCTTTTG
ACCACACAAAACAGAACCAGGACTGGACCCAGTGGAACCCAAGCCATTCAAATCCGGAAGTGCTACTTCAGACAACCACAAGGATGACTG
CAGATGTAGACAGAAATGGCACCACTGCTTATGAAGGAAACTGGAACCCAGAAGCACACCCTCCCCTCATTCACCATGAGCATCATGAGG
AAGAAGAGACCCCACATTCTACAAGCACAATCCAGGCAACTCCTAGTAGTACAACGGAAGAAACAGCTACCCAGAAGGAACAGTGGTTTG
GCAACAGATGGCATGAGGGATATCGCCAAACACCCAAAGAAGACTCCCATTCGACAACAGGGACAGCTGCAGCCTCAGCTCATACCAGCC
ATCCAATGCAAGGAAGGACAACACCAAGCCCAGAGGACAGTTCCTGGACTGATTTCTTCAACCCAATCTCACACCCCATGGGACGAGGTC
ATCAAGCAGGAAGAAGGATGGTTTCACCAGTGATCATTAAAGAATGGGCAGCTTACAAAGGAAAGTCTCCTCAAACCCCGGAACTGGTTG
AAGCTCTTGCCTTCAGGGAGTGGACCTGCCCCAACCTGAAGAGGCTGTGGTTGGGTAAGGCGGTAGAGGACAAGAACCGCAGGATGAGGG
CCTTCCTGGCCTGCATGAGGTCGGACACCCCAGCCATGCTCAACCCTGCCAACGTGCCCACTCACCTCATGGTGCTCTGCTGCGTCTTAC
GGTACATGGTGCAGTGGCCGGGAGCACGCATCCTTCGGCGTCAGGAGCTAGATGCCTTCCTGGCTCAGGCGCTGTCCCCCAAACTCTACG
AGCCTGATCAGCTCCAGGAGCTCAAGATTGAGAACCTAGATCCCCGAGGAATTCAGCTATCAGCTCTCTTCATGAGTGGAGTAGACATGG
CCTTGTTTGCAAATGATGCATGCGGACAGCCAATCCCCTGGGAACACTGTTGTCCTTGGATGTATTTTGATGGGAAGCTCTTCCAATCCA
AACTCCTCAAAGCCAGCCGGGAAAAGACCCCACTCATTGACCTCTGTGATGGTCAGGCTGATCAGGCTGCCAAGGTAGAGAAGATGCGCC
AGAGCGTCCTCGAGGGGCTCAGCTTCTCCAGGCAGAGCCACACGCTCCCTTTCCCGCCGCCACCTGCCCTGCCCTTCTACCCTGCCTCTG
CGTACCCCCGGCACTTTGGGCCTGTCCCACCCTCTCAGGGCAGGGGCAGAGGCTTTGCAGGCGTCTGTGGCTTTGGAGGCCCCTATGGGG
AAACGGTAGCAACAGGCCCTTACCGTGCCTTCCGTGTGGCGGCAGCATCGGGACACTGCGGAGCCTTCTCAGGCAGTGACAGCAGCAGGA
CTAGCAAGTCCCAGGGCGGAGTCCAACCTATACCTTCTCAGGGAGGCAAACTAGAAATAGCTGGCACTGTGGTTGGCCATTGGGCTGGGA
GCAGGCGGGGCCGTGGGGGCCGGGGGCCTTTCCCCCTGCAGGTGGTTTCTGTCGGAGGACCAGCTAGAGGGCGTCCAAGAGGAGTTATTT
CCACCCCAGTGATTAGAACATTTGGAAGAGGTGGAAGGTACTATGGCAGAGGTTACAAAAACCAGGCAGCAATTCAGGGCAGACCTCCTT
ATGCTGCTTCAGCAGAAGAAGTGGCCAAAGAACTTAAGTCAAAATCTGGGGAATCGAAGTCCTCTGCTATGTCTTCAGACGGGTCCCTGG
CTGAAAACGGAGTGATGGCCGAGGAGAAGCCGGCTCCCCAGATGAACGGGAGCACGGGTGACGCCAGGGCCCCCAGCCACTCTGAAAGTG
CCTTGAATAATGACTCTAAAACGTGCAATACAAATCCTCATTTAAATGCACTAAGTACAGACAGCGCTTGCCGCAGAGAAGCTGCTCTGG
AGGCAGCTGTCTTAAATAAAGAAGAGTAAACTTATTTTTTATAGAGGGTGAAGGATGCTGGAAGGGTAAGGATTTAGGAATATCTGGAGA
GAAAGAGAGCCTGCAGTTATGTACATTTTGTCCTTTCCGTAAGAGAAAAATGAGGACTTTGGAAATTCAGATCCCTCTTTGATATCAGAG
ATTTAAACAACACATTTTTAGTTTTAACCAGTTGTAGTCAAAATGCTACAATAAAACAAAAAAGAGAAAGAAAATGAAGAGCATTTGACT
CCCGCACTTAAAATGAAGTACACATAAAGTTTAAACTGGTTATGACAAAAGCCTTTAGTTGTGTTTCTTGAACTATAAAGAAAACAAATT
TTGGCAGTCTTTAAGTATATATAGCTTAAAATATAATTTTTAGCATTTGGCACCATATGTATGCCATTATATTTGATTTTGCATTACTGT
TTCACAATGAAGCTTTCTTTAAGGCTTTGATTTTTATGATTATGAAAGAAATAAGGCACAACCACAGTTTTTCTTTCTTAAATTTCATCA
CTGTTGATGTGGTTCTTTTGTGTTAAAAAAAAAAAGTGCAACTATCAAAACTAAAAAATTATAGAGTAATATTGCCGTTCTGCTGATTTT
AAATATACAATACATCATACATACTTTACAAGCAAGTTAAATGGAGATAAAGTTGAAATCATAGAAGATGCAAATGACCTTTCAAAATCA
ACACAATGTGTTCTGAAACTTTCGTGACTAATACCATGCATCTGTGATCAATGAACTATGTGGTTTTGAATCGGATGTAGACCATTAGTA
CTACTACTTGAGCTAAACTTCTGCATGGTTCATAATTTTTAAAGTGTGTAGTTAATATGCATGTTATCGTCCTTTCTTCCATTCTTAACA
GTATGTGCCCATTTGCAAAACAAAAATGCTAATAATCAGTAATAGTCCTATAAAAGATGTTAACTCTGTTTAGTCATTGACTGATCTTGC
TCTAACCTTAAAATTTTGTGATTATTGACCTCTGTTGCATTTATTCTAAAGCCCCCCAAAAATTATCTAGCCGTTTCGAATATCAACATT
ACCCTGGTGTATTCACTGCTGTATGCATTATTGTTCTTTGTTGCTGTTTTATGCCTTCATATTAGCAAATATGAAATTCTGTGAAAAAAA
ACCCTTTGATCTTAAAAAAAAAAAAACCACCCCCCCCTTCTGTAGCAGGAAACAAATTGCTTGTTCTTGAGAACTTTCCCATCAAGAATT
TAGTAGAAGCAGGTATACTTCTATCATTTTGATGTTTTTGTTAATGTTTCCAAACAATGTACTTTGAAATCAGAATCACTTCTTATCGTT
TTCATATACTTCTGATGCTCTTCATCACATTAGTGATCAGAAATGAGGTGTAATTCCCCAACCCCTGCCCGCAAGAGCTAAGTAGGATCT
TACTGTAAGTTGAAGGGAGTTTTGCCCTAACTCATGGATTGTGCAAGAATGAACTGCTGTTGGGTTTGATTGACTGTCGATGGATTGTGG

>In-frame_ENST00000433354_ENST00000277165_TCGA-BR-8080-01A_CD44_chr11_35227790_+_FAM120A_chr9_96305504_length(amino acids)=997AA_start in transcript=5_stop in transcript=2998
MPSGPQPLPGSVRHPRPVLRRPLPRAQGSSSSFRPRPPFAPDTMDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRT
EAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPN
AFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMST
SATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDH
TKQNQDWTQWNPSHSNPEVLLQTTTRMTADVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGN
RWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMVSPVIIKEWAAYKGKSPQTPELVEA
LAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPANVPTHLMVLCCVLRYMVQWPGARILRRQELDAFLAQALSPKLYEP
DQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPIPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQADQAAKVEKMRQS
VLEGLSFSRQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRGRGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFSGSDSSRTS
KSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPYA
ASAEEVAKELKSKSGESKSSAMSSDGSLAENGVMAEEKPAPQMNGSTGDARAPSHSESALNNDSKTCNTNPHLNALSTDSACRREAALEA

--------------------------------------------------------------
>In-frame_ENST00000428726_ENST00000277165_TCGA-BR-8080-01A_CD44_chr11_35227790_+_FAM120A_chr9_96305504_length(transcript)=4552nt_BP=1537nt
AGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGATCCTCCAGCTCC
TTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTG
GCGCAGATCGATTTGAATATAACCTGCCGCTTTGCAGGTGTATTCCACGTGGAGAAAAATGGTCGCTACAGCATCTCTCGGACGGAGGCC
GCTGACCTCTGCAAGGCTTTCAATAGCACCTTGCCCACAATGGCCCAGATGGAGAAAGCTCTGAGCATCGGATTTGAGACCTGCAGGTAT
GGGTTCATAGAAGGGCACGTGGTGATTCCCCGGATCCACCCCAACTCCATCTGTGCAGCAAACAACACAGGGGTGTACATCCTCACATCC
AACACCTCCCAGTATGACACATATTGCTTCAATGCTTCAGCTCCACCTGAAGAAGATTGTACATCAGTCACAGACCTGCCCAATGCCTTT
GATGGACCAATTACCATAACTATTGTTAACCGTGATGGCACCCGCTATGTCCAGAAAGGAGAATACAGAACGAATCCTGAAGACATCTAC
CCCAGCAACCCTACTGATGATGACGTGAGCAGCGGCTCCTCCAGTGAAAGGAGCAGCACTTCAGGAGGTTACATCTTTTACACCTTTTCT
ACTGTACACCCCATCCCAGACGAAGACAGTCCCTGGATCACCGACAGCACAGACAGAATCCCTGCTACCACTTTGATGAGCACTAGTGCT
ACAGCAACTGAGACAGCAACCAAGAGGCAAGAAACCTGGGATTGGTTTTCATGGTTGTTTCTACCATCAGAGTCAAAGAATCATCTTCAC
ACAACAACACAAATGGCTGGTACGTCTTCAAATACCATCTCAGCAGGCTGGGAGCCAAATGAAGAAAATGAAGATGAAAGAGACAGACAC
CTCAGTTTTTCTGGATCAGGCATTGATGATGATGAAGATTTTATCTCCAGCACCATTTCAACCACACCACGGGCTTTTGACCACACAAAA
CAGAACCAGGACTGGACCCAGTGGAACCCAAGCCATTCAAATCCGGAAGTGCTACTTCAGACAACCACAAGGATGACTGATGTAGACAGA
AATGGCACCACTGCTTATGAAGGAAACTGGAACCCAGAAGCACACCCTCCCCTCATTCACCATGAGCATCATGAGGAAGAAGAGACCCCA
CATTCTACAAGCACAATCCAGGCAACTCCTAGTAGTACAACGGAAGAAACAGCTACCCAGAAGGAACAGTGGTTTGGCAACAGATGGCAT
GAGGGATATCGCCAAACACCCAAAGAAGACTCCCATTCGACAACAGGGACAGCTGCAGCCTCAGCTCATACCAGCCATCCAATGCAAGGA
AGGACAACACCAAGCCCAGAGGACAGTTCCTGGACTGATTTCTTCAACCCAATCTCACACCCCATGGGACGAGGTCATCAAGCAGGAAGA
AGGATGGTTTCACCAGTGATCATTAAAGAATGGGCAGCTTACAAAGGAAAGTCTCCTCAAACCCCGGAACTGGTTGAAGCTCTTGCCTTC
AGGGAGTGGACCTGCCCCAACCTGAAGAGGCTGTGGTTGGGTAAGGCGGTAGAGGACAAGAACCGCAGGATGAGGGCCTTCCTGGCCTGC
ATGAGGTCGGACACCCCAGCCATGCTCAACCCTGCCAACGTGCCCACTCACCTCATGGTGCTCTGCTGCGTCTTACGGTACATGGTGCAG
TGGCCGGGAGCACGCATCCTTCGGCGTCAGGAGCTAGATGCCTTCCTGGCTCAGGCGCTGTCCCCCAAACTCTACGAGCCTGATCAGCTC
CAGGAGCTCAAGATTGAGAACCTAGATCCCCGAGGAATTCAGCTATCAGCTCTCTTCATGAGTGGAGTAGACATGGCCTTGTTTGCAAAT
GATGCATGCGGACAGCCAATCCCCTGGGAACACTGTTGTCCTTGGATGTATTTTGATGGGAAGCTCTTCCAATCCAAACTCCTCAAAGCC
AGCCGGGAAAAGACCCCACTCATTGACCTCTGTGATGGTCAGGCTGATCAGGCTGCCAAGGTAGAGAAGATGCGCCAGAGCGTCCTCGAG
GGGCTCAGCTTCTCCAGGCAGAGCCACACGCTCCCTTTCCCGCCGCCACCTGCCCTGCCCTTCTACCCTGCCTCTGCGTACCCCCGGCAC
TTTGGGCCTGTCCCACCCTCTCAGGGCAGGGGCAGAGGCTTTGCAGGCGTCTGTGGCTTTGGAGGCCCCTATGGGGAAACGGTAGCAACA
GGCCCTTACCGTGCCTTCCGTGTGGCGGCAGCATCGGGACACTGCGGAGCCTTCTCAGGCAGTGACAGCAGCAGGACTAGCAAGTCCCAG
GGCGGAGTCCAACCTATACCTTCTCAGGGAGGCAAACTAGAAATAGCTGGCACTGTGGTTGGCCATTGGGCTGGGAGCAGGCGGGGCCGT
GGGGGCCGGGGGCCTTTCCCCCTGCAGGTGGTTTCTGTCGGAGGACCAGCTAGAGGGCGTCCAAGAGGAGTTATTTCCACCCCAGTGATT
AGAACATTTGGAAGAGGTGGAAGGTACTATGGCAGAGGTTACAAAAACCAGGCAGCAATTCAGGGCAGACCTCCTTATGCTGCTTCAGCA
GAAGAAGTGGCCAAAGAACTTAAGTCAAAATCTGGGGAATCGAAGTCCTCTGCTATGTCTTCAGACGGGTCCCTGGCTGAAAACGGAGTG
ATGGCCGAGGAGAAGCCGGCTCCCCAGATGAACGGGAGCACGGGTGACGCCAGGGCCCCCAGCCACTCTGAAAGTGCCTTGAATAATGAC
TCTAAAACGTGCAATACAAATCCTCATTTAAATGCACTAAGTACAGACAGCGCTTGCCGCAGAGAAGCTGCTCTGGAGGCAGCTGTCTTA
AATAAAGAAGAGTAAACTTATTTTTTATAGAGGGTGAAGGATGCTGGAAGGGTAAGGATTTAGGAATATCTGGAGAGAAAGAGAGCCTGC
AGTTATGTACATTTTGTCCTTTCCGTAAGAGAAAAATGAGGACTTTGGAAATTCAGATCCCTCTTTGATATCAGAGATTTAAACAACACA
TTTTTAGTTTTAACCAGTTGTAGTCAAAATGCTACAATAAAACAAAAAAGAGAAAGAAAATGAAGAGCATTTGACTCCCGCACTTAAAAT
GAAGTACACATAAAGTTTAAACTGGTTATGACAAAAGCCTTTAGTTGTGTTTCTTGAACTATAAAGAAAACAAATTTTGGCAGTCTTTAA
GTATATATAGCTTAAAATATAATTTTTAGCATTTGGCACCATATGTATGCCATTATATTTGATTTTGCATTACTGTTTCACAATGAAGCT
TTCTTTAAGGCTTTGATTTTTATGATTATGAAAGAAATAAGGCACAACCACAGTTTTTCTTTCTTAAATTTCATCACTGTTGATGTGGTT
CTTTTGTGTTAAAAAAAAAAAGTGCAACTATCAAAACTAAAAAATTATAGAGTAATATTGCCGTTCTGCTGATTTTAAATATACAATACA
TCATACATACTTTACAAGCAAGTTAAATGGAGATAAAGTTGAAATCATAGAAGATGCAAATGACCTTTCAAAATCAACACAATGTGTTCT
GAAACTTTCGTGACTAATACCATGCATCTGTGATCAATGAACTATGTGGTTTTGAATCGGATGTAGACCATTAGTACTACTACTTGAGCT
AAACTTCTGCATGGTTCATAATTTTTAAAGTGTGTAGTTAATATGCATGTTATCGTCCTTTCTTCCATTCTTAACAGTATGTGCCCATTT
GCAAAACAAAAATGCTAATAATCAGTAATAGTCCTATAAAAGATGTTAACTCTGTTTAGTCATTGACTGATCTTGCTCTAACCTTAAAAT
TTTGTGATTATTGACCTCTGTTGCATTTATTCTAAAGCCCCCCAAAAATTATCTAGCCGTTTCGAATATCAACATTACCCTGGTGTATTC
ACTGCTGTATGCATTATTGTTCTTTGTTGCTGTTTTATGCCTTCATATTAGCAAATATGAAATTCTGTGAAAAAAAACCCTTTGATCTTA
AAAAAAAAAAAACCACCCCCCCCTTCTGTAGCAGGAAACAAATTGCTTGTTCTTGAGAACTTTCCCATCAAGAATTTAGTAGAAGCAGGT
ATACTTCTATCATTTTGATGTTTTTGTTAATGTTTCCAAACAATGTACTTTGAAATCAGAATCACTTCTTATCGTTTTCATATACTTCTG
ATGCTCTTCATCACATTAGTGATCAGAAATGAGGTGTAATTCCCCAACCCCTGCCCGCAAGAGCTAAGTAGGATCTTACTGTAAGTTGAA
GGGAGTTTTGCCCTAACTCATGGATTGTGCAAGAATGAACTGCTGTTGGGTTTGATTGACTGTCGATGGATTGTGGTGTGGTGTATCTGA

>In-frame_ENST00000428726_ENST00000277165_TCGA-BR-8080-01A_CD44_chr11_35227790_+_FAM120A_chr9_96305504_length(amino acids)=989AA_start in transcript=15_stop in transcript=2984
MPGSVRHPRPVLRRPLPRAQGSSSSFRPRPPFAPDTMDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCK
AFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPIT
ITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATET
ATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDW
TQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQ
TPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMVSPVIIKEWAAYKGKSPQTPELVEALAFREWTC
PNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPANVPTHLMVLCCVLRYMVQWPGARILRRQELDAFLAQALSPKLYEPDQLQELKI
ENLDPRGIQLSALFMSGVDMALFANDACGQPIPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQADQAAKVEKMRQSVLEGLSFS
RQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRGRGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGGVQP
IPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPYAASAEEVAK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CD44-FAM120A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneFAM120Achr11:35227790chr9:96305504ENST0000037538909339_4050629.0YES1%2C SRC and FYN


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneFAM120Achr11:35227790chr9:96305504ENST00000277165918339_405636.33333333333341119.0YES1%2C SRC and FYN
TgeneFAM120Achr11:35227790chr9:96305504ENST000003339361019339_405664.33333333333341147.0YES1%2C SRC and FYN
TgeneFAM120Achr11:35227790chr9:96305504ENST00000340893917339_405636.33333333333341073.0YES1%2C SRC and FYN


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CD44-FAM120A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneCD44P16070DB08818Hyaluronic acidSmall moleculeApproved|Vet_approved
HgeneCD44P16070DB08818Hyaluronic acidSmall moleculeApproved|Vet_approved
HgeneCD44P16070DB08818Hyaluronic acidSmall moleculeApproved|Vet_approved
HgeneCD44P16070DB08818Hyaluronic acidSmall moleculeApproved|Vet_approved
HgeneCD44P16070DB08818Hyaluronic acidSmall moleculeApproved|Vet_approved

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Related Diseases for CD44-FAM120A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCD44C0023487Acute Promyelocytic Leukemia2CTD_human
HgeneCD44C0009405Hereditary Nonpolyposis Colorectal Neoplasms1CTD_human
HgeneCD44C0011616Contact Dermatitis1CTD_human
HgeneCD44C0017661IGA Glomerulonephritis1CTD_human
HgeneCD44C0022660Kidney Failure, Acute1CTD_human
HgeneCD44C0023467Leukemia, Myelocytic, Acute1CTD_human
HgeneCD44C0024623Malignant neoplasm of stomach1CTD_human
HgeneCD44C0024668Mammary Neoplasms, Experimental1CTD_human
HgeneCD44C0026998Acute Myeloid Leukemia, M11CTD_human
HgeneCD44C0027627Neoplasm Metastasis1CTD_human
HgeneCD44C0027746Nerve Degeneration1CTD_human
HgeneCD44C0030297Pancreatic Neoplasm1CTD_human
HgeneCD44C0032580Adenomatous Polyposis Coli1CTD_human
HgeneCD44C0037274Dermatologic disorders1CTD_human
HgeneCD44C0038356Stomach Neoplasms1CTD_human
HgeneCD44C0042900Vitiligo1CTD_human
HgeneCD44C0162351Contact hypersensitivity1CTD_human
HgeneCD44C0274861Arsenic Poisoning, Inorganic1CTD_human
HgeneCD44C0274862Nervous System, Organic Arsenic Poisoning1CTD_human
HgeneCD44C0311375Arsenic Poisoning1CTD_human
HgeneCD44C0346647Malignant neoplasm of pancreas1CTD_human
HgeneCD44C0751851Arsenic Encephalopathy1CTD_human
HgeneCD44C0751852Arsenic Induced Polyneuropathy1CTD_human
HgeneCD44C1333990Hereditary Nonpolyposis Colorectal Cancer1CTD_human
HgeneCD44C1565662Acute Kidney Insufficiency1CTD_human
HgeneCD44C1708349Hereditary Diffuse Gastric Cancer1CTD_human
HgeneCD44C1879321Acute Myeloid Leukemia (AML-M2)1CTD_human
HgeneCD44C2609414Acute kidney injury1CTD_human
HgeneCD44C2713442Polyposis, Adenomatous Intestinal1CTD_human
HgeneCD44C2713443Familial Intestinal Polyposis1CTD_human
HgeneCD44C4552100Lynch Syndrome1CTD_human