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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CD74-SOD2 (FusionGDB2 ID:14694)

Fusion Gene Summary for CD74-SOD2

check button Fusion gene summary
Fusion gene informationFusion gene name: CD74-SOD2
Fusion gene ID: 14694
HgeneTgene
Gene symbol

CD74

SOD2

Gene ID

972

100129518

Gene nameCD74 moleculeSOD2 overlapping transcript 1
SynonymsDHLAG|HLADG|II|Ia-GAMMA|p33SOD2
Cytomap

5q33.1

6q25.3

Type of geneprotein-codingncRNA
DescriptionHLA class II histocompatibility antigen gamma chainCD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)CD74 molecule, major histocompatibility complex, class II invariant chainHLA-DR antigens-associated Superoxide dismutase [Mn], mitochondrial
Modification date2020031320200313
UniProtAcc

P04233

.
Ensembl transtripts involved in fusion geneENST00000377795, ENST00000353334, 
ENST00000524315, ENST00000009530, 
ENST00000546087, ENST00000538183, 
ENST00000367055, ENST00000367054, 
ENST00000444946, ENST00000337404, 
ENST00000452684, ENST00000535372, 
Fusion gene scores* DoF score43 X 51 X 20=4386013 X 22 X 6=1716
# samples 5922
** MAII scorelog2(59/43860*10)=-6.21604704731175
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(22/1716*10)=-2.96347412397489
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CD74 [Title/Abstract] AND SOD2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCD74(149781314)-SOD2(160102509), # samples:1
CD74(149781751)-SOD2(160114221), # samples:1
CD74(149781551)-SOD2(160101113), # samples:1
CD74(149781385)-SOD2(160100449), # samples:1
CD74(149781513)-SOD2(160102705), # samples:1
CD74(149781345)-SOD2(160105941), # samples:1
CD74(149781401)-SOD2(160106026), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCD74

GO:0001516

prostaglandin biosynthetic process

12782713

HgeneCD74

GO:0001934

positive regulation of protein phosphorylation

24942581

HgeneCD74

GO:0002792

negative regulation of peptide secretion

19849849

HgeneCD74

GO:0033674

positive regulation of kinase activity

24942581

HgeneCD74

GO:0043066

negative regulation of apoptotic process

12782713

HgeneCD74

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB signaling

24942581

HgeneCD74

GO:0043410

positive regulation of MAPK cascade

24942581

HgeneCD74

GO:0043518

negative regulation of DNA damage response, signal transduction by p53 class mediator

17045821

HgeneCD74

GO:0045657

positive regulation of monocyte differentiation

24942581

HgeneCD74

GO:0045893

positive regulation of transcription, DNA-templated

24942581

HgeneCD74

GO:0046598

positive regulation of viral entry into host cell

24942581

HgeneCD74

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

17045821

HgeneCD74

GO:0070374

positive regulation of ERK1 and ERK2 cascade

17045821|24942581


check buttonFusion gene breakpoints across CD74 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across SOD2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRCTCGA-B8-5164-01ACD74chr5

149781314

+SOD2chr6

160102509

-
ChimerDB4KIRCTCGA-B8-5164-01ACD74chr5

149781751

+SOD2chr6

160114221

-
ChimerDB4KIRCTCGA-A3-3319-01ACD74chr5

149781551

+SOD2chr6

160101113

-
ChimerDB4BRCATCGA-EW-A1PB-01ACD74chr5

149781385

+SOD2chr6

160100449

-
ChimerDB4BRCATCGA-EW-A1PB-01ACD74chr5

149781513

+SOD2chr6

160102705

-
ChimerDB4BRCATCGA-EW-A1P4-01ACD74chr5

149781345

+SOD2chr6

160105941

-
ChiTaRS5.0N/AAA934677CD74chr5

149781401

+SOD2chr6

160106026

+


Top

Fusion Gene ORF analysis for CD74-SOD2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-intronENST00000377795ENST00000546087CD74chr5

149781314

+SOD2chr6

160102509

-
intron-3UTRENST00000377795ENST00000538183CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000377795ENST00000367055CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000377795ENST00000367054CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000377795ENST00000444946CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000377795ENST00000337404CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000377795ENST00000452684CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000377795ENST00000535372CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000353334ENST00000546087CD74chr5

149781314

+SOD2chr6

160102509

-
intron-3UTRENST00000353334ENST00000538183CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000353334ENST00000367055CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000353334ENST00000367054CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000353334ENST00000444946CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000353334ENST00000337404CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000353334ENST00000452684CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000353334ENST00000535372CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000524315ENST00000546087CD74chr5

149781314

+SOD2chr6

160102509

-
intron-3UTRENST00000524315ENST00000538183CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000524315ENST00000367055CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000524315ENST00000367054CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000524315ENST00000444946CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000524315ENST00000337404CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000524315ENST00000452684CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000524315ENST00000535372CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000009530ENST00000546087CD74chr5

149781314

+SOD2chr6

160102509

-
intron-3UTRENST00000009530ENST00000538183CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000009530ENST00000367055CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000009530ENST00000367054CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000009530ENST00000444946CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000009530ENST00000337404CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000009530ENST00000452684CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000009530ENST00000535372CD74chr5

149781314

+SOD2chr6

160102509

-
intron-intronENST00000377795ENST00000546087CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000377795ENST00000538183CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000377795ENST00000367055CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000377795ENST00000367054CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000377795ENST00000444946CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000377795ENST00000337404CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000377795ENST00000452684CD74chr5

149781751

+SOD2chr6

160114221

-
intron-intronENST00000377795ENST00000535372CD74chr5

149781751

+SOD2chr6

160114221

-
intron-intronENST00000353334ENST00000546087CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000353334ENST00000538183CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000353334ENST00000367055CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000353334ENST00000367054CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000353334ENST00000444946CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000353334ENST00000337404CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000353334ENST00000452684CD74chr5

149781751

+SOD2chr6

160114221

-
intron-intronENST00000353334ENST00000535372CD74chr5

149781751

+SOD2chr6

160114221

-
intron-intronENST00000524315ENST00000546087CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000524315ENST00000538183CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000524315ENST00000367055CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000524315ENST00000367054CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000524315ENST00000444946CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000524315ENST00000337404CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000524315ENST00000452684CD74chr5

149781751

+SOD2chr6

160114221

-
intron-intronENST00000524315ENST00000535372CD74chr5

149781751

+SOD2chr6

160114221

-
intron-intronENST00000009530ENST00000546087CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000009530ENST00000538183CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000009530ENST00000367055CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000009530ENST00000367054CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000009530ENST00000444946CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000009530ENST00000337404CD74chr5

149781751

+SOD2chr6

160114221

-
intron-5UTRENST00000009530ENST00000452684CD74chr5

149781751

+SOD2chr6

160114221

-
intron-intronENST00000009530ENST00000535372CD74chr5

149781751

+SOD2chr6

160114221

-
intron-intronENST00000377795ENST00000546087CD74chr5

149781551

+SOD2chr6

160101113

-
intron-3UTRENST00000377795ENST00000538183CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000377795ENST00000367055CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000377795ENST00000367054CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000377795ENST00000444946CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000377795ENST00000337404CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000377795ENST00000452684CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000377795ENST00000535372CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000353334ENST00000546087CD74chr5

149781551

+SOD2chr6

160101113

-
intron-3UTRENST00000353334ENST00000538183CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000353334ENST00000367055CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000353334ENST00000367054CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000353334ENST00000444946CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000353334ENST00000337404CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000353334ENST00000452684CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000353334ENST00000535372CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000524315ENST00000546087CD74chr5

149781551

+SOD2chr6

160101113

-
intron-3UTRENST00000524315ENST00000538183CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000524315ENST00000367055CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000524315ENST00000367054CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000524315ENST00000444946CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000524315ENST00000337404CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000524315ENST00000452684CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000524315ENST00000535372CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000009530ENST00000546087CD74chr5

149781551

+SOD2chr6

160101113

-
intron-3UTRENST00000009530ENST00000538183CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000009530ENST00000367055CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000009530ENST00000367054CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000009530ENST00000444946CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000009530ENST00000337404CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000009530ENST00000452684CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000009530ENST00000535372CD74chr5

149781551

+SOD2chr6

160101113

-
intron-intronENST00000377795ENST00000546087CD74chr5

149781385

+SOD2chr6

160100449

-
intron-3UTRENST00000377795ENST00000538183CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000377795ENST00000367055CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000377795ENST00000367054CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000377795ENST00000444946CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000377795ENST00000337404CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000377795ENST00000452684CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000377795ENST00000535372CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000353334ENST00000546087CD74chr5

149781385

+SOD2chr6

160100449

-
intron-3UTRENST00000353334ENST00000538183CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000353334ENST00000367055CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000353334ENST00000367054CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000353334ENST00000444946CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000353334ENST00000337404CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000353334ENST00000452684CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000353334ENST00000535372CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000524315ENST00000546087CD74chr5

149781385

+SOD2chr6

160100449

-
intron-3UTRENST00000524315ENST00000538183CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000524315ENST00000367055CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000524315ENST00000367054CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000524315ENST00000444946CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000524315ENST00000337404CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000524315ENST00000452684CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000524315ENST00000535372CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000009530ENST00000546087CD74chr5

149781385

+SOD2chr6

160100449

-
intron-3UTRENST00000009530ENST00000538183CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000009530ENST00000367055CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000009530ENST00000367054CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000009530ENST00000444946CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000009530ENST00000337404CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000009530ENST00000452684CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000009530ENST00000535372CD74chr5

149781385

+SOD2chr6

160100449

-
intron-intronENST00000377795ENST00000546087CD74chr5

149781513

+SOD2chr6

160102705

-
intron-3UTRENST00000377795ENST00000538183CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000377795ENST00000367055CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000377795ENST00000367054CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000377795ENST00000444946CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000377795ENST00000337404CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000377795ENST00000452684CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000377795ENST00000535372CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000353334ENST00000546087CD74chr5

149781513

+SOD2chr6

160102705

-
intron-3UTRENST00000353334ENST00000538183CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000353334ENST00000367055CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000353334ENST00000367054CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000353334ENST00000444946CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000353334ENST00000337404CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000353334ENST00000452684CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000353334ENST00000535372CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000524315ENST00000546087CD74chr5

149781513

+SOD2chr6

160102705

-
intron-3UTRENST00000524315ENST00000538183CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000524315ENST00000367055CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000524315ENST00000367054CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000524315ENST00000444946CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000524315ENST00000337404CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000524315ENST00000452684CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000524315ENST00000535372CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000009530ENST00000546087CD74chr5

149781513

+SOD2chr6

160102705

-
intron-3UTRENST00000009530ENST00000538183CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000009530ENST00000367055CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000009530ENST00000367054CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000009530ENST00000444946CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000009530ENST00000337404CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000009530ENST00000452684CD74chr5

149781513

+SOD2chr6

160102705

-
intron-intronENST00000009530ENST00000535372CD74chr5

149781513

+SOD2chr6

160102705

-
intron-3CDSENST00000377795ENST00000546087CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000377795ENST00000538183CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000377795ENST00000367055CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000377795ENST00000367054CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000377795ENST00000444946CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000377795ENST00000337404CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000377795ENST00000452684CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000377795ENST00000535372CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000353334ENST00000546087CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000353334ENST00000538183CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000353334ENST00000367055CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000353334ENST00000367054CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000353334ENST00000444946CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000353334ENST00000337404CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000353334ENST00000452684CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000353334ENST00000535372CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000524315ENST00000546087CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000524315ENST00000538183CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000524315ENST00000367055CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000524315ENST00000367054CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000524315ENST00000444946CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000524315ENST00000337404CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000524315ENST00000452684CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000524315ENST00000535372CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000009530ENST00000546087CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000009530ENST00000538183CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000009530ENST00000367055CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000009530ENST00000367054CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000009530ENST00000444946CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000009530ENST00000337404CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000009530ENST00000452684CD74chr5

149781345

+SOD2chr6

160105941

-
intron-intronENST00000009530ENST00000535372CD74chr5

149781345

+SOD2chr6

160105941

-
intron-3CDSENST00000377795ENST00000546087CD74chr5

149781401

+SOD2chr6

160106026

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intron-3CDSENST00000377795ENST00000538183CD74chr5

149781401

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160106026

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intron-3CDSENST00000377795ENST00000367055CD74chr5

149781401

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160106026

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intron-3CDSENST00000377795ENST00000367054CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000377795ENST00000444946CD74chr5

149781401

+SOD2chr6

160106026

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intron-intronENST00000377795ENST00000337404CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000377795ENST00000452684CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000377795ENST00000535372CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000353334ENST00000546087CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000353334ENST00000538183CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000353334ENST00000367055CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000353334ENST00000367054CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000353334ENST00000444946CD74chr5

149781401

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intron-intronENST00000353334ENST00000337404CD74chr5

149781401

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intron-intronENST00000353334ENST00000452684CD74chr5

149781401

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160106026

+
intron-intronENST00000353334ENST00000535372CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000524315ENST00000546087CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000524315ENST00000538183CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000524315ENST00000367055CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000524315ENST00000367054CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000524315ENST00000444946CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000524315ENST00000337404CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000524315ENST00000452684CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000524315ENST00000535372CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000009530ENST00000546087CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000009530ENST00000538183CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000009530ENST00000367055CD74chr5

149781401

+SOD2chr6

160106026

+
intron-3CDSENST00000009530ENST00000367054CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000009530ENST00000444946CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000009530ENST00000337404CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000009530ENST00000452684CD74chr5

149781401

+SOD2chr6

160106026

+
intron-intronENST00000009530ENST00000535372CD74chr5

149781401

+SOD2chr6

160106026

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for CD74-SOD2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CD74-SOD2


check button Go to

FGviewer for the breakpoints of :-:

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CD74

P04233

.
FUNCTION: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.; FUNCTION: [Class-II-associated invariant chain peptide]: Binds to the peptide-binding site of MHC class II alpha/beta heterodimers forming an alpha-beta-CLIP complex, thereby preventing the loading of antigenic peptides to the MHC class II complex until its release by HLA-DM in the endosome. {ECO:0000269|PubMed:1448172}.; FUNCTION: [Isoform p41]: Stabilizes the conformation of mature CTSL by binding to its active site and serving as a chaperone to help maintain a pool of mature enzyme in endocytic compartments and extracellular space of antigen-presenting cells (APCs). Has antiviral activity by stymieing the endosomal entry of Ebola virus and coronaviruses, including SARS-CoV-2 (PubMed:32855215). Disrupts cathepsin-mediated Ebola virus glycoprotein processing, which prevents viral fusion and entry. This antiviral activity is specific to p41 isoform (PubMed:32855215). {ECO:0000250|UniProtKB:P04441, ECO:0000269|PubMed:32855215}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for CD74-SOD2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for CD74-SOD2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CD74-SOD2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CD74-SOD2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCD74C0006142Malignant neoplasm of breast1CTD_human
HgeneCD74C0007131Non-Small Cell Lung Carcinoma1CTD_human
HgeneCD74C0023893Liver Cirrhosis, Experimental1CTD_human
HgeneCD74C0162557Liver Failure, Acute1CTD_human
HgeneCD74C0678222Breast Carcinoma1CTD_human
HgeneCD74C1257931Mammary Neoplasms, Human1CTD_human
HgeneCD74C1458155Mammary Neoplasms1CTD_human
HgeneCD74C4704874Mammary Carcinoma, Human1CTD_human
TgeneSOD2C0033578Prostatic Neoplasms8CTD_human
TgeneSOD2C0376358Malignant neoplasm of prostate8CTD_human
TgeneSOD2C0235874Disease Exacerbation7CTD_human
TgeneSOD2C0006826Malignant Neoplasms6CTD_human
TgeneSOD2C0027626Neoplasm Invasiveness6CTD_human
TgeneSOD2C0027651Neoplasms6CTD_human
TgeneSOD2C0035126Reperfusion Injury6CTD_human
TgeneSOD2C0086692Benign Neoplasm6CTD_human
TgeneSOD2C0007621Neoplastic Cell Transformation5CTD_human
TgeneSOD2C0018801Heart failure5CTD_human
TgeneSOD2C0018802Congestive heart failure5CTD_human
TgeneSOD2C0023212Left-Sided Heart Failure5CTD_human
TgeneSOD2C0235527Heart Failure, Right-Sided5CTD_human
TgeneSOD2C1959583Myocardial Failure5CTD_human
TgeneSOD2C1961112Heart Decompensation5CTD_human
TgeneSOD2C0006142Malignant neoplasm of breast4CTD_human
TgeneSOD2C0007114Malignant neoplasm of skin4CTD_human
TgeneSOD2C0024623Malignant neoplasm of stomach4CTD_human
TgeneSOD2C0025500Mesothelioma4CTD_human
TgeneSOD2C0027627Neoplasm Metastasis4CTD_human
TgeneSOD2C0036341Schizophrenia4PSYGENET
TgeneSOD2C0037286Skin Neoplasms4CTD_human
TgeneSOD2C0038356Stomach Neoplasms4CTD_human
TgeneSOD2C0678222Breast Carcinoma4CTD_human
TgeneSOD2C1257931Mammary Neoplasms, Human4CTD_human
TgeneSOD2C1458155Mammary Neoplasms4CTD_human
TgeneSOD2C1708349Hereditary Diffuse Gastric Cancer4CTD_human
TgeneSOD2C2239176Liver carcinoma4CTD_human
TgeneSOD2C4704874Mammary Carcinoma, Human4CTD_human
TgeneSOD2C0003873Rheumatoid Arthritis3CTD_human
TgeneSOD2C0007786Brain Ischemia3CTD_human
TgeneSOD2C0020538Hypertensive disease3CTD_human
TgeneSOD2C0024232Lymphatic Metastasis3CTD_human
TgeneSOD2C0028754Obesity3CTD_human
TgeneSOD2C0029408Degenerative polyarthritis3CTD_human
TgeneSOD2C0030567Parkinson Disease3CTD_human
TgeneSOD2C0086743Osteoarthrosis Deformans3CTD_human
TgeneSOD2C0270715Degenerative Diseases, Central Nervous System3CTD_human
TgeneSOD2C0524851Neurodegenerative Disorders3CTD_human
TgeneSOD2C0751733Degenerative Diseases, Spinal Cord3CTD_human
TgeneSOD2C0917798Cerebral Ischemia3CTD_human
TgeneSOD2C0002152Alloxan Diabetes2CTD_human
TgeneSOD2C0002896Sideroblastic anemia2CTD_human
TgeneSOD2C0003129Anoxemia2CTD_human
TgeneSOD2C0003130Anoxia2CTD_human
TgeneSOD2C0004153Atherosclerosis2CTD_human
TgeneSOD2C0005586Bipolar Disorder2PSYGENET
TgeneSOD2C0005684Malignant neoplasm of urinary bladder2CTD_human
TgeneSOD2C0005695Bladder Neoplasm2CTD_human
TgeneSOD2C0007097Carcinoma2CTD_human
TgeneSOD2C0007131Non-Small Cell Lung Carcinoma2CTD_human
TgeneSOD2C0007137Squamous cell carcinoma2CTD_human
TgeneSOD2C0007193Cardiomyopathy, Dilated2CTD_human
TgeneSOD2C0009402Colorectal Carcinoma2CTD_human
TgeneSOD2C0009404Colorectal Neoplasms2CTD_human
TgeneSOD2C0011853Diabetes Mellitus, Experimental2CTD_human
TgeneSOD2C0014859Esophageal Neoplasms2CTD_human
TgeneSOD2C0022116Ischemia2CTD_human
TgeneSOD2C0022658Kidney Diseases2CTD_human
TgeneSOD2C0026640Mouth Neoplasms2CTD_human
TgeneSOD2C0027540Necrosis2CTD_human
TgeneSOD2C0032927Precancerous Conditions2CTD_human
TgeneSOD2C0034535Radiation Syndrome2CTD_human
TgeneSOD2C0038433Streptozotocin Diabetes2CTD_human
TgeneSOD2C0042164Uveitis2CTD_human
TgeneSOD2C0085207Gestational Diabetes2CTD_human
TgeneSOD2C0153381Malignant neoplasm of mouth2CTD_human
TgeneSOD2C0162674Chronic progressive external ophthalmoplegia2CTD_human
TgeneSOD2C0205696Anaplastic carcinoma2CTD_human
TgeneSOD2C0205697Carcinoma, Spindle-Cell2CTD_human
TgeneSOD2C0205698Undifferentiated carcinoma2CTD_human
TgeneSOD2C0205699Carcinomatosis2CTD_human
TgeneSOD2C0242184Hypoxia2CTD_human
TgeneSOD2C0279626Squamous cell carcinoma of esophagus2CTD_human
TgeneSOD2C0282313Condition, Preneoplastic2CTD_human
TgeneSOD2C0546837Malignant neoplasm of esophagus2CTD_human
TgeneSOD2C0700292Hypoxemia2CTD_human
TgeneSOD2C0919267ovarian neoplasm2CTD_human
TgeneSOD2C1140680Malignant neoplasm of ovary2CTD_human
TgeneSOD2C1449563Cardiomyopathy, Familial Idiopathic2CTD_human
TgeneSOD2C1510432Radiation Sickness2CTD_human
TgeneSOD2C1563937Atherogenesis2CTD_human
TgeneSOD2C0001418Adenocarcinoma1CTD_human
TgeneSOD2C0001787Osteoporosis, Age-Related1CTD_human
TgeneSOD2C0001925Albuminuria1CTD_human
TgeneSOD2C0001969Alcoholic Intoxication1PSYGENET
TgeneSOD2C0002390Extrinsic allergic alveolitis1CTD_human
TgeneSOD2C0002395Alzheimer's Disease1CTD_human
TgeneSOD2C0002736Amyotrophic Lateral Sclerosis1CTD_human
TgeneSOD2C0002871Anemia1CTD_human
TgeneSOD2C0003493Aortic Diseases1CTD_human
TgeneSOD2C0004045Asphyxia Neonatorum1CTD_human
TgeneSOD2C0004364Autoimmune Diseases1CTD_human
TgeneSOD2C0006118Brain Neoplasms1CTD_human
TgeneSOD2C0007102Malignant tumor of colon1CTD_human
TgeneSOD2C0007134Renal Cell Carcinoma1CTD_human
TgeneSOD2C0007682CNS disorder1CTD_human
TgeneSOD2C0007787Transient Ischemic Attack1CTD_human
TgeneSOD2C0009375Colonic Neoplasms1CTD_human
TgeneSOD2C0011265Presenile dementia1CTD_human
TgeneSOD2C0011570Mental Depression1PSYGENET
TgeneSOD2C0011574Involutional Depression1CTD_human
TgeneSOD2C0011581Depressive disorder1PSYGENET
TgeneSOD2C0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
TgeneSOD2C0011881Diabetic Nephropathy1CTD_human
TgeneSOD2C0014866Esophageal Stenosis1CTD_human
TgeneSOD2C0014868Esophagitis1CTD_human
TgeneSOD2C0015695Fatty Liver1CTD_human
TgeneSOD2C0015967Fever1CTD_human
TgeneSOD2C0016059Fibrosis1CTD_human
TgeneSOD2C0017667Nodular glomerulosclerosis1CTD_human
TgeneSOD2C0018200Granuloma, Respiratory Tract1CTD_human
TgeneSOD2C0018800Cardiomegaly1CTD_human
TgeneSOD2C0019193Hepatitis, Toxic1CTD_human
TgeneSOD2C0020542Pulmonary Hypertension1CTD_human
TgeneSOD2C0020550Hyperthyroidism1CTD_human
TgeneSOD2C0020615Hypoglycemia1CTD_human
TgeneSOD2C0021364Male infertility1CTD_human
TgeneSOD2C0021367Mammary Ductal Carcinoma1CTD_human
TgeneSOD2C0021655Insulin Resistance1CTD_human
TgeneSOD2C0022333Jacksonian Seizure1CTD_human
TgeneSOD2C0022665Kidney Neoplasm1CTD_human
TgeneSOD2C0022672Acute Kidney Tubular Necrosis1CTD_human
TgeneSOD2C0023891Liver Cirrhosis, Alcoholic1CTD_human
TgeneSOD2C0024115Lung diseases1CTD_human
TgeneSOD2C0024668Mammary Neoplasms, Experimental1CTD_human
TgeneSOD2C0024796Marfan Syndrome1CTD_human
TgeneSOD2C0025312Meningomyelocele1CTD_human
TgeneSOD2C0026764Multiple Myeloma1CTD_human
TgeneSOD2C0027051Myocardial Infarction1CTD_human
TgeneSOD2C0027726Nephrotic Syndrome1CTD_human
TgeneSOD2C0027746Nerve Degeneration1CTD_human
TgeneSOD2C0029456Osteoporosis1CTD_human
TgeneSOD2C0029459Osteoporosis, Senile1CTD_human
TgeneSOD2C0030246Pustulosis of Palms and Soles1CTD_human
TgeneSOD2C0030297Pancreatic Neoplasm1CTD_human
TgeneSOD2C0030354Papilloma1CTD_human
TgeneSOD2C0032580Adenomatous Polyposis Coli1CTD_human
TgeneSOD2C0033141Cardiomyopathies, Primary1CTD_human
TgeneSOD2C0033860Psoriasis1CTD_human
TgeneSOD2C0033937Psychoses, Drug1CTD_human
TgeneSOD2C0033941Psychoses, Substance-Induced1CTD_human
TgeneSOD2C0035222Respiratory Distress Syndrome, Adult1CTD_human
TgeneSOD2C0036202Sarcoidosis1CTD_human
TgeneSOD2C0036529Myocardial Diseases, Secondary1CTD_human
TgeneSOD2C0036572Seizures1CTD_human
TgeneSOD2C0036980Shock, Cardiogenic1CTD_human
TgeneSOD2C0037268Skin Abnormalities1CTD_human
TgeneSOD2C0037274Dermatologic disorders1CTD_human
TgeneSOD2C0040411Tongue Neoplasms1CTD_human
TgeneSOD2C0041408Turner Syndrome1CTD_human
TgeneSOD2C0042373Vascular Diseases1CTD_human
TgeneSOD2C0079744Diffuse Large B-Cell Lymphoma1CTD_human
TgeneSOD2C0086664Myelocele1CTD_human
TgeneSOD2C0149958Complex partial seizures1CTD_human
TgeneSOD2C0151526Premature Birth1CTD_human
TgeneSOD2C0151744Myocardial Ischemia1CTD_human
TgeneSOD2C0152013Adenocarcinoma of lung (disorder)1CTD_human
TgeneSOD2C0153349Malignant neoplasm of tongue1CTD_human
TgeneSOD2C0153633Malignant neoplasm of brain1CTD_human
TgeneSOD2C0162309Adrenoleukodystrophy1CTD_human
TgeneSOD2C0162671MELAS Syndrome1CTD_human
TgeneSOD2C0162871Aortic Aneurysm, Abdominal1CTD_human
TgeneSOD2C0205641Adenocarcinoma, Basal Cell1CTD_human
TgeneSOD2C0205642Adenocarcinoma, Oxyphilic1CTD_human
TgeneSOD2C0205643Carcinoma, Cribriform1CTD_human
TgeneSOD2C0205644Carcinoma, Granular Cell1CTD_human
TgeneSOD2C0205645Adenocarcinoma, Tubular1CTD_human
TgeneSOD2C0205874Papilloma, Squamous Cell1CTD_human
TgeneSOD2C0205875Papillomatosis1CTD_human
TgeneSOD2C0206061Pneumonia, Interstitial1CTD_human
TgeneSOD2C0206062Lung Diseases, Interstitial1CTD_human
TgeneSOD2C0206160Reticulocytosis1CTD_human
TgeneSOD2C0234533Generalized seizures1CTD_human
TgeneSOD2C0234535Clonic Seizures1CTD_human
TgeneSOD2C0235974Pancreatic carcinoma1CTD_human
TgeneSOD2C0238281Middle Cerebral Artery Syndrome1CTD_human
TgeneSOD2C0238461Anaplastic thyroid carcinoma1CTD_human
TgeneSOD2C0242526Gonadal Dysgenesis, 45,X1CTD_human
TgeneSOD2C0242698Ventricular Dysfunction, Left1CTD_human
TgeneSOD2C0242992Multiple Chemical Sensitivity1CTD_human
TgeneSOD2C0268255Farber Lipogranulomatosis1CTD_human
TgeneSOD2C0268583Methylmalonic acidemia1CTD_human
TgeneSOD2C0270824Visual seizure1CTD_human
TgeneSOD2C0270844Tonic Seizures1CTD_human
TgeneSOD2C0270846Epileptic drop attack1CTD_human
TgeneSOD2C0271708Fasting Hypoglycemia1CTD_human
TgeneSOD2C0271710Reactive hypoglycemia1CTD_human
TgeneSOD2C0274861Arsenic Poisoning, Inorganic1CTD_human
TgeneSOD2C0274862Nervous System, Organic Arsenic Poisoning1CTD_human
TgeneSOD2C0276496Familial Alzheimer Disease (FAD)1CTD_human
TgeneSOD2C0279702Conventional (Clear Cell) Renal Cell Carcinoma1CTD_human
TgeneSOD2C0311375Arsenic Poisoning1CTD_human
TgeneSOD2C0345967Malignant mesothelioma1CTD_human
TgeneSOD2C0346647Malignant neoplasm of pancreas1CTD_human
TgeneSOD2C0376618Endotoxemia1CTD_human
TgeneSOD2C0393554Amyotrophic Lateral Sclerosis With Dementia1CTD_human
TgeneSOD2C0422850Seizures, Somatosensory1CTD_human
TgeneSOD2C0422852Seizures, Auditory1CTD_human
TgeneSOD2C0422853Olfactory seizure1CTD_human
TgeneSOD2C0422854Gustatory seizure1CTD_human
TgeneSOD2C0422855Vertiginous seizure1CTD_human
TgeneSOD2C0472381Posterior Circulation Transient Ischemic Attack1CTD_human
TgeneSOD2C0494463Alzheimer Disease, Late Onset1CTD_human
TgeneSOD2C0494475Tonic - clonic seizures1CTD_human
TgeneSOD2C0496899Benign neoplasm of brain, unspecified1CTD_human
TgeneSOD2C0520459Necrotizing Enterocolitis1CTD_human
TgeneSOD2C0543859Amyotrophic Lateral Sclerosis, Guam Form1CTD_human
TgeneSOD2C0546126Acute Confusional Senile Dementia1CTD_human
TgeneSOD2C0740376Middle Cerebral Artery Thrombosis1CTD_human
TgeneSOD2C0740391Middle Cerebral Artery Occlusion1CTD_human
TgeneSOD2C0740392Infarction, Middle Cerebral Artery1CTD_human
TgeneSOD2C0740457Malignant neoplasm of kidney1CTD_human
TgeneSOD2C0750900Alzheimer's Disease, Focal Onset1CTD_human
TgeneSOD2C0750901Alzheimer Disease, Early Onset1CTD_human
TgeneSOD2C0750974Brain Tumor, Primary1CTD_human
TgeneSOD2C0750977Recurrent Brain Neoplasm1CTD_human
TgeneSOD2C0750979Primary malignant neoplasm of brain1CTD_human
TgeneSOD2C0751019Carotid Circulation Transient Ischemic Attack1CTD_human
TgeneSOD2C0751020Transient Ischemic Attack, Vertebrobasilar Circulation1CTD_human
TgeneSOD2C0751021Crescendo Transient Ischemic Attacks1CTD_human
TgeneSOD2C0751022Brain Stem Ischemia, Transient1CTD_human
TgeneSOD2C0751056Non-epileptic convulsion1CTD_human
TgeneSOD2C0751110Single Seizure1CTD_human
TgeneSOD2C0751123Atonic Absence Seizures1CTD_human
TgeneSOD2C0751316Acquired Meningomyelocele1CTD_human
TgeneSOD2C0751406Post-Traumatic Osteoporosis1CTD_human
TgeneSOD2C0751494Convulsive Seizures1CTD_human
TgeneSOD2C0751495Seizures, Focal1CTD_human
TgeneSOD2C0751496Seizures, Sensory1CTD_human
TgeneSOD2C0751651Mitochondrial Diseases1CTD_human
TgeneSOD2C0751845Middle Cerebral Artery Embolus1CTD_human
TgeneSOD2C0751846Left Middle Cerebral Artery Infarction1CTD_human
TgeneSOD2C0751847Embolic Infarction, Middle Cerebral Artery1CTD_human
TgeneSOD2C0751848Thrombotic Infarction, Middle Cerebral Artery1CTD_human
TgeneSOD2C0751849Right Middle Cerebral Artery Infarction1CTD_human
TgeneSOD2C0751851Arsenic Encephalopathy1CTD_human
TgeneSOD2C0751852Arsenic Induced Polyneuropathy1CTD_human
TgeneSOD2C0752347Lewy Body Disease1CTD_human
TgeneSOD2C0848676Subfertility, Male1CTD_human
TgeneSOD2C0860207Drug-Induced Liver Disease1CTD_human
TgeneSOD2C0878544Cardiomyopathies1CTD_human
TgeneSOD2C0917731Male sterility1CTD_human
TgeneSOD2C0917805Transient Cerebral Ischemia1CTD_human
TgeneSOD2C0920563Insulin Sensitivity1CTD_human
TgeneSOD2C0948089Acute Coronary Syndrome1CTD_human
TgeneSOD2C0949855Electron Transport Chain Deficiencies, Mitochondrial1CTD_human
TgeneSOD2C0949856Oxidative Phosphorylation Deficiencies1CTD_human
TgeneSOD2C0949857Mitochondrial Respiratory Chain Deficiencies1CTD_human
TgeneSOD2C1134719Invasive Ductal Breast Carcinoma1CTD_human
TgeneSOD2C1168401Squamous cell carcinoma of the head and neck1CTD_human
TgeneSOD2C1262760Hepatitis, Drug-Induced1CTD_human
TgeneSOD2C1266042Chromophobe Renal Cell Carcinoma1CTD_human
TgeneSOD2C1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
TgeneSOD2C1266044Collecting Duct Carcinoma of the Kidney1CTD_human
TgeneSOD2C1269683Major Depressive Disorder1CTD_human
TgeneSOD2C1306837Papillary Renal Cell Carcinoma1CTD_human
TgeneSOD2C1383860Cardiac Hypertrophy1CTD_human
TgeneSOD2C1527168Bonnevie-Ullrich Syndrome1CTD_human
TgeneSOD2C1527231Adrenomyeloneuropathy1CTD_human
TgeneSOD2C1527335Transient Ischemic Attack, Anterior Circulation1CTD_human
TgeneSOD2C1527390Neoplasms, Intracranial1CTD_human
TgeneSOD2C1571983Involutional paraphrenia1CTD_human
TgeneSOD2C1571984Psychosis, Involutional1CTD_human
TgeneSOD2C1623038Cirrhosis1CTD_human
TgeneSOD2C1855119Methylmalonic aciduria1CTD_human
TgeneSOD2C1859317Cataract and cardiomyopathy1CTD_human
TgeneSOD2C2711227Steatohepatitis1CTD_human
TgeneSOD2C2713442Polyposis, Adenomatous Intestinal1CTD_human
TgeneSOD2C2713443Familial Intestinal Polyposis1CTD_human
TgeneSOD2C2931822Nasopharyngeal carcinoma1CTD_human
TgeneSOD2C3495874Nonepileptic Seizures1CTD_human
TgeneSOD2C3658290Drug-Induced Acute Liver Injury1CTD_human
TgeneSOD2C3714618Primary Hyperthyroidism1CTD_human
TgeneSOD2C4048158Convulsions1CTD_human
TgeneSOD2C4277682Chemical and Drug Induced Liver Injury1CTD_human
TgeneSOD2C4279912Chemically-Induced Liver Toxicity1CTD_human
TgeneSOD2C4316903Absence Seizures1CTD_human
TgeneSOD2C4317109Epileptic Seizures1CTD_human
TgeneSOD2C4317123Myoclonic Seizures1CTD_human
TgeneSOD2C4505436Generalized Absence Seizures1CTD_human
TgeneSOD2C4551650Esophageal Stricture1CTD_human
TgeneSOD2C4721453Peripheral Nervous System Diseases1CTD_human
TgeneSOD2C4721845Marfan Syndrome, Type I1CTD_human