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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CDH1-YWHAH (FusionGDB2 ID:15035)

Fusion Gene Summary for CDH1-YWHAH

check button Fusion gene summary
Fusion gene informationFusion gene name: CDH1-YWHAH
Fusion gene ID: 15035
HgeneTgene
Gene symbol

CDH1

YWHAH

Gene ID

51343

7533

Gene namefizzy and cell division cycle 20 related 1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
SynonymsCDC20C|CDH1|FZR|FZR2|HCDH|HCDH1YWHA1
Cytomap

19p13.3

22q12.3

Type of geneprotein-codingprotein-coding
Descriptionfizzy-related protein homologCDC20 homolog 1CDC20-like 1bCDC20-like protein 1cdh1/Hct1 homologfizzy/cell division cycle 20 related 114-3-3 protein eta14-3-3 etatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
Modification date2020031320200327
UniProtAcc

P12830

.
Ensembl transtripts involved in fusion geneENST00000261769, ENST00000422392, 
ENST00000562836, 		ENST00000248975, 
ENST00000397492, ENST00000471374, 
Fusion gene scores* DoF score21 X 16 X 8=26889 X 7 X 6=378
# samples 2913
** MAII scorelog2(29/2688*10)=-3.21240833276383
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/378*10)=-1.53987461119262
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CDH1 [Title/Abstract] AND YWHAH [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCDH1(68772314)-YWHAH(32352126), # samples:1
Anticipated loss of major functional domain due to fusion event.CDH1-YWHAH seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
CDH1-YWHAH seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCDH1

GO:0031145

anaphase-promoting complex-dependent catabolic process

18662541|21596315

HgeneCDH1

GO:0072425

signal transduction involved in G2 DNA damage checkpoint

18662541

HgeneCDH1

GO:1904668

positive regulation of ubiquitin protein ligase activity

11459826

TgeneYWHAH

GO:0002028

regulation of sodium ion transport

16728661

TgeneYWHAH

GO:0006713

glucocorticoid catabolic process

15790729

TgeneYWHAH

GO:0042921

glucocorticoid receptor signaling pathway

15790729

TgeneYWHAH

GO:0045893

positive regulation of transcription, DNA-templated

15790729

TgeneYWHAH

GO:0086010

membrane depolarization during action potential

16728661

TgeneYWHAH

GO:2000649

regulation of sodium ion transmembrane transporter activity

16728661


check buttonFusion gene breakpoints across CDH1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across YWHAH (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-5799-01ACDH1chr16

68772314

+YWHAHchr22

32352126

+


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Fusion Gene ORF analysis for CDH1-YWHAH

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000261769ENST00000248975CDH1chr16

68772314

+YWHAHchr22

32352126

+
In-frameENST00000261769ENST00000397492CDH1chr16

68772314

+YWHAHchr22

32352126

+
5CDS-3UTRENST00000261769ENST00000471374CDH1chr16

68772314

+YWHAHchr22

32352126

+
Frame-shiftENST00000422392ENST00000248975CDH1chr16

68772314

+YWHAHchr22

32352126

+
In-frameENST00000422392ENST00000397492CDH1chr16

68772314

+YWHAHchr22

32352126

+
5CDS-3UTRENST00000422392ENST00000471374CDH1chr16

68772314

+YWHAHchr22

32352126

+
intron-3CDSENST00000562836ENST00000248975CDH1chr16

68772314

+YWHAHchr22

32352126

+
intron-3CDSENST00000562836ENST00000397492CDH1chr16

68772314

+YWHAHchr22

32352126

+
intron-3UTRENST00000562836ENST00000471374CDH1chr16

68772314

+YWHAHchr22

32352126

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000261769CDH1chr1668772314+ENST00000397492YWHAHchr2232352126+1819354451007320
ENST00000422392CDH1chr1668772314+ENST00000397492YWHAHchr2232352126+169222735880281

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000261769ENST00000397492CDH1chr1668772314+YWHAHchr2232352126+0.0016050610.9983949
ENST00000422392ENST00000397492CDH1chr1668772314+YWHAHchr2232352126+0.0010977390.9989022

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Fusion Genomic Features for CDH1-YWHAH


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CDH1chr1668772314+YWHAHchr2232352125+2.41E-141
CDH1chr1668772314+YWHAHchr2232352125+2.41E-141

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CDH1-YWHAH


check button Go to

FGviewer for the breakpoints of chr16:68772314-chr22:32352126

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CDH1

P12830

.
FUNCTION: Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. {ECO:0000269|PubMed:11976333, ECO:0000269|PubMed:16417575}.; FUNCTION: E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. {ECO:0000269|PubMed:16417575}.; FUNCTION: (Microbial infection) Serves as a receptor for Listeria monocytogenes; internalin A (InlA) binds to this protein and promotes uptake of the bacteria. {ECO:0000269|PubMed:10406800, ECO:0000269|PubMed:17540170, ECO:0000269|PubMed:8601315}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCDH1chr16:68772314chr22:32352126ENST00000261769+216838_85154.333333333333336883.0Compositional biasNote=Ser-rich
HgeneCDH1chr16:68772314chr22:32352126ENST00000261769+216155_26254.333333333333336883.0DomainCadherin 1
HgeneCDH1chr16:68772314chr22:32352126ENST00000261769+216263_37554.333333333333336883.0DomainCadherin 2
HgeneCDH1chr16:68772314chr22:32352126ENST00000261769+216376_48654.333333333333336883.0DomainCadherin 3
HgeneCDH1chr16:68772314chr22:32352126ENST00000261769+216487_59354.333333333333336883.0DomainCadherin 4
HgeneCDH1chr16:68772314chr22:32352126ENST00000261769+216594_69754.333333333333336883.0DomainCadherin 5
HgeneCDH1chr16:68772314chr22:32352126ENST00000261769+216758_76954.333333333333336883.0RegionNote=Required for binding CTNND1 and PSEN1
HgeneCDH1chr16:68772314chr22:32352126ENST00000261769+216811_88254.333333333333336883.0RegionNote=Required for binding alpha%2C beta and gamma catenins
HgeneCDH1chr16:68772314chr22:32352126ENST00000261769+216155_70954.333333333333336883.0Topological domainExtracellular
HgeneCDH1chr16:68772314chr22:32352126ENST00000261769+216731_88254.333333333333336883.0Topological domainCytoplasmic
HgeneCDH1chr16:68772314chr22:32352126ENST00000261769+216710_73054.333333333333336883.0TransmembraneHelical


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Fusion Gene Sequence for CDH1-YWHAH


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000261769_ENST00000397492_TCGA-CD-5799-01A_CDH1_chr16_68772314_+_YWHAH_chr22_32352126_length(transcript)=1819nt_BP=354nt
AGCCAATCAGCGGTACGGGGGGCGGTGCCTCCGGGGCTCACCTGGCTGCAGCCACGCACCCCCTCTCAGTGGCGTCGGAACTGCAAAGCA
CCTGTGAGCTTGCGGAAGTCAGTTCAGACTCCAGCCCGCTCCAGCCCGGCCCGACCCGACCGCACCCGGCGCCTGCCCTCGCTCGGCGTC
CCCGGCCAGCCATGGGCCCTTGGAGCCGCAGCCTCTCGGCGCTGCTGCTGCTGCTGCAGGTCTCCTCTTGGCTCTGCCAGGAGCCGGAGC
CCTGCCACCCTGGCTTTGACGCCGAGAGCTACACGTTCACGGTGCCCCGGCGCCACCTGGAGAGAGGCCGCGTCCTGGGCAGAGGTGACA
GAGCTGAATGAACCTCTCTCCAATGAAGATCGAAATCTCCTCTCTGTGGCCTACAAGAATGTGGTTGGTGCCAGGCGATCTTCCTGGAGG
GTCATTAGCAGCATTGAGCAGAAAACCATGGCTGATGGAAACGAAAAGAAATTGGAGAAAGTTAAAGCTTACCGGGAGAAGATTGAGAAG
GAGCTGGAGACAGTTTGCAATGATGTCCTGTCTCTGCTTGACAAGTTCCTGATCAAGAACTGCAATGATTTCCAGTATGAGAGCAAGGTG
TTTTACCTGAAAATGAAGGGTGATTACTACCGCTACTTAGCAGAGGTCGCTTCTGGGGAGAAGAAAAACAGTGTGGTCGAAGCTTCTGAA
GCTGCCTACAAGGAAGCCTTTGAAATCAGCAAAGAGCAGATGCAACCCACGCATCCCATCCGGCTGGGCCTGGCCCTCAACTTCTCCGTG
TTCTACTATGAGATCCAGAATGCACCTGAGCAAGCCTGCCTCTTAGCCAAACAAGCCTTCGATGATGCCATAGCTGAGCTGGACACACTA
AACGAGGATTCCTATAAGGACTCCACGCTGATCATGCAGTTGCTGCGAGACAACCTCACCCTCTGGACGAGCGACCAGCAGGATGAAGAA
GCAGGAGAAGGCAACTGAAGATCCTTCAGGTCCCCTGGCCCTTCCTTCACCCACCACCCCCATCATCACCGATTCTTCCTTGCCACAATC
ACTAAATATCTAGTGCTAAACCTATCTGTATTGGCAGCACAGCTACTCAGATCTGCACTCCTGTCTCTTGGGAAGCAGTTTCAGATAAAT
CATGGGCATTGCTGGACTGATGGTTGCTTTGAGCCCACAGGAGCTCCCTTTTTGAATTGTGTGGAGAAGTGTGTTCTGATGAGGCATTTT
ACTATGCCTGTTGATCTATGGGAAATCTAGGCGAAAGTAATGGGGAAGATTAGAAAGAATTAGCCAACCAGGCTACAGTTGATATTTAAA
AGATCCATTTAAAACAAGCTGATAGTGTTTCGTTAAGCAGTACATCTTGTGCATGCAAAAATGAATTCACCCCTCCCACCTCTTTCTTCA
ATTAATGGAAAACTGTTAAGGGAAGCTGATACAGAGAGACAACTTGCTCCTTTCCATCAGCTTTATAATAAACTGTTTAACGTGAGGTTT
CAGTAGCTCCTTGGTTTTGCCTCTTTAAATTATGACGTGCACAAACCTTCTTTTCAATGCAATGCATCTGAAAGTTTTGATACTTGTAAC
TTTTTTTTTTTTTTGGTTGCAATTGTTTAAGAATCATGGATTTATTTTTTGTAACTCTTTGGCTATTGTCCTTGTGTATCCTGACAGCGC
CATGTGTGTCAGCCCATGTCAATCAAGATGGGTGATTATGAAATGCCAGACTTCTAAAATAAATGTTTTGGAATTCAATGGGTAAATAAA

>In-frame_ENST00000261769_ENST00000397492_TCGA-CD-5799-01A_CDH1_chr16_68772314_+_YWHAH_chr22_32352126_length(amino acids)=320AA_start in transcript=45_stop in transcript=1007
MQPRTPSQWRRNCKAPVSLRKSVQTPARSSPARPDRTRRLPSLGVPGQPWALGAAASRRCCCCCRSPLGSARSRSPATLALTPRATRSRC
PGATWREAASWAEVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDK
FLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFSVFYYEIQNAPEQACLL

--------------------------------------------------------------
>In-frame_ENST00000422392_ENST00000397492_TCGA-CD-5799-01A_CDH1_chr16_68772314_+_YWHAH_chr22_32352126_length(transcript)=1692nt_BP=227nt
GCTCCAGCCCGGCCCGACCCGACCGCACCCGGCGCCTGCCCTCGCTCGGCGTCCCCGGCCAGCCATGGGCCCTTGGAGCCGCAGCCTCTC
GGCGCTGCTGCTGCTGCTGCAGGTCTCCTCTTGGCTCTGCCAGGAGCCGGAGCCCTGCCACCCTGGCTTTGACGCCGAGAGCTACACGTT
CACGGTGCCCCGGCGCCACCTGGAGAGAGGCCGCGTCCTGGGCAGAGGTGACAGAGCTGAATGAACCTCTCTCCAATGAAGATCGAAATC
TCCTCTCTGTGGCCTACAAGAATGTGGTTGGTGCCAGGCGATCTTCCTGGAGGGTCATTAGCAGCATTGAGCAGAAAACCATGGCTGATG
GAAACGAAAAGAAATTGGAGAAAGTTAAAGCTTACCGGGAGAAGATTGAGAAGGAGCTGGAGACAGTTTGCAATGATGTCCTGTCTCTGC
TTGACAAGTTCCTGATCAAGAACTGCAATGATTTCCAGTATGAGAGCAAGGTGTTTTACCTGAAAATGAAGGGTGATTACTACCGCTACT
TAGCAGAGGTCGCTTCTGGGGAGAAGAAAAACAGTGTGGTCGAAGCTTCTGAAGCTGCCTACAAGGAAGCCTTTGAAATCAGCAAAGAGC
AGATGCAACCCACGCATCCCATCCGGCTGGGCCTGGCCCTCAACTTCTCCGTGTTCTACTATGAGATCCAGAATGCACCTGAGCAAGCCT
GCCTCTTAGCCAAACAAGCCTTCGATGATGCCATAGCTGAGCTGGACACACTAAACGAGGATTCCTATAAGGACTCCACGCTGATCATGC
AGTTGCTGCGAGACAACCTCACCCTCTGGACGAGCGACCAGCAGGATGAAGAAGCAGGAGAAGGCAACTGAAGATCCTTCAGGTCCCCTG
GCCCTTCCTTCACCCACCACCCCCATCATCACCGATTCTTCCTTGCCACAATCACTAAATATCTAGTGCTAAACCTATCTGTATTGGCAG
CACAGCTACTCAGATCTGCACTCCTGTCTCTTGGGAAGCAGTTTCAGATAAATCATGGGCATTGCTGGACTGATGGTTGCTTTGAGCCCA
CAGGAGCTCCCTTTTTGAATTGTGTGGAGAAGTGTGTTCTGATGAGGCATTTTACTATGCCTGTTGATCTATGGGAAATCTAGGCGAAAG
TAATGGGGAAGATTAGAAAGAATTAGCCAACCAGGCTACAGTTGATATTTAAAAGATCCATTTAAAACAAGCTGATAGTGTTTCGTTAAG
CAGTACATCTTGTGCATGCAAAAATGAATTCACCCCTCCCACCTCTTTCTTCAATTAATGGAAAACTGTTAAGGGAAGCTGATACAGAGA
GACAACTTGCTCCTTTCCATCAGCTTTATAATAAACTGTTTAACGTGAGGTTTCAGTAGCTCCTTGGTTTTGCCTCTTTAAATTATGACG
TGCACAAACCTTCTTTTCAATGCAATGCATCTGAAAGTTTTGATACTTGTAACTTTTTTTTTTTTTTGGTTGCAATTGTTTAAGAATCAT
GGATTTATTTTTTGTAACTCTTTGGCTATTGTCCTTGTGTATCCTGACAGCGCCATGTGTGTCAGCCCATGTCAATCAAGATGGGTGATT

>In-frame_ENST00000422392_ENST00000397492_TCGA-CD-5799-01A_CDH1_chr16_68772314_+_YWHAH_chr22_32352126_length(amino acids)=281AA_start in transcript=35_stop in transcript=880
MPSLGVPGQPWALGAAASRRCCCCCRSPLGSARSRSPATLALTPRATRSRCPGATWREAASWAEVTELNEPLSNEDRNLLSVAYKNVVGA
RRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNS
VVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CDH1-YWHAH


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CDH1-YWHAH


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CDH1-YWHAH


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCDH1C1708349Hereditary Diffuse Gastric Cancer15CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneCDH1C0346153Breast Cancer, Familial12CLINGEN
HgeneCDH1C0009405Hereditary Nonpolyposis Colorectal Neoplasms6CLINGEN
HgeneCDH1C0024623Malignant neoplasm of stomach6CGI;CTD_human;UNIPROT
HgeneCDH1C0038356Stomach Neoplasms6CGI;CTD_human
HgeneCDH1C1112155Hereditary non-polyposis colorectal cancer syndrome6CLINGEN
HgeneCDH1C1333990Hereditary Nonpolyposis Colorectal Cancer6CLINGEN
HgeneCDH1C1333991Hereditary Non-Polyposis Colon Cancer Type 26CLINGEN
HgeneCDH1C2936783Colorectal cancer, hereditary nonpolyposis, type 16CLINGEN
HgeneCDH1C0006142Malignant neoplasm of breast4CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneCDH1C0033578Prostatic Neoplasms4CTD_human
HgeneCDH1C0376358Malignant neoplasm of prostate4CTD_human;GENOMICS_ENGLAND
HgeneCDH1C0678222Breast Carcinoma4CTD_human
HgeneCDH1C1257931Mammary Neoplasms, Human4CTD_human
HgeneCDH1C1458155Mammary Neoplasms4CTD_human
HgeneCDH1C4704874Mammary Carcinoma, Human4CTD_human
HgeneCDH1C0007097Carcinoma3CTD_human
HgeneCDH1C0205696Anaplastic carcinoma3CTD_human
HgeneCDH1C0205697Carcinoma, Spindle-Cell3CTD_human
HgeneCDH1C0205698Undifferentiated carcinoma3CTD_human
HgeneCDH1C0205699Carcinomatosis3CTD_human
HgeneCDH1C0005684Malignant neoplasm of urinary bladder2CTD_human
HgeneCDH1C0005695Bladder Neoplasm2CTD_human
HgeneCDH1C0009402Colorectal Carcinoma2CTD_human
HgeneCDH1C0009404Colorectal Neoplasms2CTD_human
HgeneCDH1C0019207Hepatoma, Morris2CTD_human
HgeneCDH1C0019208Hepatoma, Novikoff2CTD_human
HgeneCDH1C0021367Mammary Ductal Carcinoma2CTD_human
HgeneCDH1C0023904Liver Neoplasms, Experimental2CTD_human
HgeneCDH1C0027626Neoplasm Invasiveness2CTD_human
HgeneCDH1C0027627Neoplasm Metastasis2CTD_human
HgeneCDH1C0086404Experimental Hepatoma2CTD_human
HgeneCDH1C0206692Carcinoma, Lobular2CGI;CTD_human;UNIPROT
HgeneCDH1C1134719Invasive Ductal Breast Carcinoma2CTD_human
HgeneCDH1C2931456Prostate cancer, familial2CTD_human
HgeneCDH1C4551988BLEPHAROCHEILODONTIC SYNDROME 12GENOMICS_ENGLAND;UNIPROT
HgeneCDH1C4722327PROSTATE CANCER, HEREDITARY, 12CTD_human
HgeneCDH1C0007137Squamous cell carcinoma1CTD_human
HgeneCDH1C0007621Neoplastic Cell Transformation1CTD_human
HgeneCDH1C0009324Ulcerative Colitis1CTD_human
HgeneCDH1C0010606Adenoid Cystic Carcinoma1CTD_human
HgeneCDH1C0014170Endometrial Neoplasms1CTD_human
HgeneCDH1C0014476Eperythrozoonosis1CTD_human
HgeneCDH1C0024667Animal Mammary Neoplasms1CTD_human
HgeneCDH1C0024668Mammary Neoplasms, Experimental1CTD_human
HgeneCDH1C0025500Mesothelioma1CTD_human
HgeneCDH1C0026936Mycoplasma Infections1CTD_human
HgeneCDH1C0027645Neoplasm Seeding1CTD_human
HgeneCDH1C0027659Neoplasms, Experimental1CTD_human
HgeneCDH1C0027746Nerve Degeneration1CTD_human
HgeneCDH1C0030297Pancreatic Neoplasm1CTD_human
HgeneCDH1C0032927Precancerous Conditions1CTD_human
HgeneCDH1C0036095Salivary Gland Neoplasms1CTD_human
HgeneCDH1C0079487Helicobacter Infections1CTD_human
HgeneCDH1C0158646Cleft palate with cleft lip1ORPHANET
HgeneCDH1C0220636Malignant neoplasm of salivary gland1CTD_human
HgeneCDH1C0235874Disease Exacerbation1CTD_human
HgeneCDH1C0282313Condition, Preneoplastic1CTD_human
HgeneCDH1C0282612Prostatic Intraepithelial Neoplasias1CTD_human
HgeneCDH1C0346647Malignant neoplasm of pancreas1CTD_human
HgeneCDH1C0476089Endometrial Carcinoma1CTD_human;GENOMICS_ENGLAND
HgeneCDH1C0919267ovarian neoplasm1CTD_human
HgeneCDH1C1140680Malignant neoplasm of ovary1CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneCDH1C1176475Ductal Carcinoma1CTD_human
HgeneCDH1C1257925Mammary Carcinoma, Animal1CTD_human
HgeneCDH1C1861536Blepharo-cheilo-dontic syndrome1ORPHANET
TgeneYWHAHC0002152Alloxan Diabetes1CTD_human
TgeneYWHAHC0005586Bipolar Disorder1PSYGENET
TgeneYWHAHC0011853Diabetes Mellitus, Experimental1CTD_human
TgeneYWHAHC0033141Cardiomyopathies, Primary1CTD_human
TgeneYWHAHC0036529Myocardial Diseases, Secondary1CTD_human
TgeneYWHAHC0038433Streptozotocin Diabetes1CTD_human
TgeneYWHAHC0878544Cardiomyopathies1CTD_human