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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CHD3-RAD51C (FusionGDB2 ID:16351)

Fusion Gene Summary for CHD3-RAD51C

check button Fusion gene summary
Fusion gene informationFusion gene name: CHD3-RAD51C
Fusion gene ID: 16351
HgeneTgene
Gene symbol

CHD3

RAD51C

Gene ID

1107

5889

Gene namechromodomain helicase DNA binding protein 3RAD51 paralog C
SynonymsMi-2a|Mi2-ALPHA|SNIBCPS|ZFHBROVCA3|FANCO|R51H3|RAD51L2
Cytomap

17p13.1

17q22

Type of geneprotein-codingprotein-coding
Descriptionchromodomain-helicase-DNA-binding protein 3ATP-dependent helicase CHD3CHD-3hZFHmi-2 autoantigen 240 kDa proteinzinc finger helicasezinc-finger helicase (Snf2-like)DNA repair protein RAD51 homolog 3RAD51-like protein 2yeast RAD51 homolog 3
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000380358, ENST00000358181, 
ENST00000330494, ENST00000570758, 
ENST00000583539, ENST00000337432, 
ENST00000487921, ENST00000421782, 
Fusion gene scores* DoF score6 X 6 X 2=7212 X 11 X 4=528
# samples 715
** MAII scorelog2(7/72*10)=-0.0406419844973459
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/528*10)=-1.81557542886257
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CHD3 [Title/Abstract] AND RAD51C [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCHD3(7797253)-RAD51C(56787220), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCHD3

GO:0007051

spindle organization

17626165

HgeneCHD3

GO:0007098

centrosome cycle

17626165

TgeneRAD51C

GO:0006281

DNA repair

19451272

TgeneRAD51C

GO:0006310

DNA recombination

19451272


check buttonFusion gene breakpoints across CHD3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across RAD51C (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ACCTCGA-OR-A5KY-01ACHD3chr17

7797253

+RAD51Cchr17

56787220

+
ChimerDB4ACCTCGA-OR-A5KYCHD3chr17

7797253

+RAD51Cchr17

56787219

+
ChimerDB4ACCTCGA-OR-A5KY-01ACHD3chr17

7797253

+RAD51Cchr17

56787220

+
ChimerDB4ACCTCGA-OR-A5KY-01ACHD3chr17

7797253

-RAD51Cchr17

56787220

+


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Fusion Gene ORF analysis for CHD3-RAD51C

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000380358ENST00000583539CHD3chr17

7797253

+RAD51Cchr17

56787220

+
In-frameENST00000380358ENST00000337432CHD3chr17

7797253

+RAD51Cchr17

56787220

+
5CDS-intronENST00000380358ENST00000487921CHD3chr17

7797253

+RAD51Cchr17

56787220

+
5CDS-intronENST00000380358ENST00000421782CHD3chr17

7797253

+RAD51Cchr17

56787220

+
In-frameENST00000358181ENST00000583539CHD3chr17

7797253

+RAD51Cchr17

56787220

+
In-frameENST00000358181ENST00000337432CHD3chr17

7797253

+RAD51Cchr17

56787220

+
5CDS-intronENST00000358181ENST00000487921CHD3chr17

7797253

+RAD51Cchr17

56787220

+
5CDS-intronENST00000358181ENST00000421782CHD3chr17

7797253

+RAD51Cchr17

56787220

+
In-frameENST00000330494ENST00000583539CHD3chr17

7797253

+RAD51Cchr17

56787220

+
In-frameENST00000330494ENST00000337432CHD3chr17

7797253

+RAD51Cchr17

56787220

+
5CDS-intronENST00000330494ENST00000487921CHD3chr17

7797253

+RAD51Cchr17

56787220

+
5CDS-intronENST00000330494ENST00000421782CHD3chr17

7797253

+RAD51Cchr17

56787220

+
intron-3CDSENST00000570758ENST00000583539CHD3chr17

7797253

+RAD51Cchr17

56787220

+
intron-3CDSENST00000570758ENST00000337432CHD3chr17

7797253

+RAD51Cchr17

56787220

+
intron-intronENST00000570758ENST00000487921CHD3chr17

7797253

+RAD51Cchr17

56787220

+
intron-intronENST00000570758ENST00000421782CHD3chr17

7797253

+RAD51Cchr17

56787220

+
In-frameENST00000380358ENST00000583539CHD3chr17

7797253

+RAD51Cchr17

56787219

+
In-frameENST00000380358ENST00000337432CHD3chr17

7797253

+RAD51Cchr17

56787219

+
5CDS-intronENST00000380358ENST00000487921CHD3chr17

7797253

+RAD51Cchr17

56787219

+
5CDS-intronENST00000380358ENST00000421782CHD3chr17

7797253

+RAD51Cchr17

56787219

+
In-frameENST00000358181ENST00000583539CHD3chr17

7797253

+RAD51Cchr17

56787219

+
In-frameENST00000358181ENST00000337432CHD3chr17

7797253

+RAD51Cchr17

56787219

+
5CDS-intronENST00000358181ENST00000487921CHD3chr17

7797253

+RAD51Cchr17

56787219

+
5CDS-intronENST00000358181ENST00000421782CHD3chr17

7797253

+RAD51Cchr17

56787219

+
In-frameENST00000330494ENST00000583539CHD3chr17

7797253

+RAD51Cchr17

56787219

+
In-frameENST00000330494ENST00000337432CHD3chr17

7797253

+RAD51Cchr17

56787219

+
5CDS-intronENST00000330494ENST00000487921CHD3chr17

7797253

+RAD51Cchr17

56787219

+
5CDS-intronENST00000330494ENST00000421782CHD3chr17

7797253

+RAD51Cchr17

56787219

+
intron-3CDSENST00000570758ENST00000583539CHD3chr17

7797253

+RAD51Cchr17

56787219

+
intron-3CDSENST00000570758ENST00000337432CHD3chr17

7797253

+RAD51Cchr17

56787219

+
intron-intronENST00000570758ENST00000487921CHD3chr17

7797253

+RAD51Cchr17

56787219

+
intron-intronENST00000570758ENST00000421782CHD3chr17

7797253

+RAD51Cchr17

56787219

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000380358CHD3chr177797253+ENST00000583539RAD51Cchr1756787220+1645110211437478
ENST00000380358CHD3chr177797253+ENST00000337432RAD51Cchr1756787220+1648110211527508
ENST00000358181CHD3chr177797253+ENST00000583539RAD51Cchr1756787220+167711342101469419
ENST00000358181CHD3chr177797253+ENST00000337432RAD51Cchr1756787220+168011342101559449
ENST00000330494CHD3chr177797253+ENST00000583539RAD51Cchr1756787220+161710741501409419
ENST00000330494CHD3chr177797253+ENST00000337432RAD51Cchr1756787220+162010741501499449
ENST00000380358CHD3chr177797253+ENST00000583539RAD51Cchr1756787219+1645110211437478
ENST00000380358CHD3chr177797253+ENST00000337432RAD51Cchr1756787219+1648110211527508
ENST00000358181CHD3chr177797253+ENST00000583539RAD51Cchr1756787219+167711342101469419
ENST00000358181CHD3chr177797253+ENST00000337432RAD51Cchr1756787219+168011342101559449
ENST00000330494CHD3chr177797253+ENST00000583539RAD51Cchr1756787219+161710741501409419
ENST00000330494CHD3chr177797253+ENST00000337432RAD51Cchr1756787219+162010741501499449

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000380358ENST00000583539CHD3chr177797253+RAD51Cchr1756787220+0.008773410.9912266
ENST00000380358ENST00000337432CHD3chr177797253+RAD51Cchr1756787220+0.0075248230.9924752
ENST00000358181ENST00000583539CHD3chr177797253+RAD51Cchr1756787220+0.003291310.99670863
ENST00000358181ENST00000337432CHD3chr177797253+RAD51Cchr1756787220+0.0033653410.99663466
ENST00000330494ENST00000583539CHD3chr177797253+RAD51Cchr1756787220+0.0038359590.9961641
ENST00000330494ENST00000337432CHD3chr177797253+RAD51Cchr1756787220+0.0039718720.9960282
ENST00000380358ENST00000583539CHD3chr177797253+RAD51Cchr1756787219+0.008773410.9912266
ENST00000380358ENST00000337432CHD3chr177797253+RAD51Cchr1756787219+0.0075248230.9924752
ENST00000358181ENST00000583539CHD3chr177797253+RAD51Cchr1756787219+0.003291310.99670863
ENST00000358181ENST00000337432CHD3chr177797253+RAD51Cchr1756787219+0.0033653410.99663466
ENST00000330494ENST00000583539CHD3chr177797253+RAD51Cchr1756787219+0.0038359590.9961641
ENST00000330494ENST00000337432CHD3chr177797253+RAD51Cchr1756787219+0.0039718720.9960282

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Fusion Genomic Features for CHD3-RAD51C


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CHD3chr177797253+RAD51Cchr1756787219+2.77E-060.99999726
CHD3chr177797253+RAD51Cchr1756787219+2.77E-060.99999726
CHD3chr177797253+RAD51Cchr1756787219+2.77E-060.99999726
CHD3chr177797253+RAD51Cchr1756787219+2.77E-060.99999726

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CHD3-RAD51C


check button Go to

FGviewer for the breakpoints of chr17:7797253-chr17:56787220

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640206_221308.02001.0Compositional biasNote=Poly-Ala
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640243_246308.02001.0Compositional biasNote=Poly-Pro
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639206_221308.01967.0Compositional biasNote=Poly-Ala
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639243_246308.01967.0Compositional biasNote=Poly-Pro
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640206_221367.02060.0Compositional biasNote=Poly-Ala
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640243_246367.02060.0Compositional biasNote=Poly-Pro
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640355_358367.02060.0Compositional biasNote=Poly-Lys
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640206_221308.02001.0Compositional biasNote=Poly-Ala
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640243_246308.02001.0Compositional biasNote=Poly-Pro
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639206_221308.01967.0Compositional biasNote=Poly-Ala
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639243_246308.01967.0Compositional biasNote=Poly-Pro
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640206_221367.02060.0Compositional biasNote=Poly-Ala
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640243_246367.02060.0Compositional biasNote=Poly-Pro
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640355_358367.02060.0Compositional biasNote=Poly-Lys
TgeneRAD51Cchr17:7797253chr17:56787219ENST0000033743239366_370235.0377.0MotifNuclear localization signal
TgeneRAD51Cchr17:7797253chr17:56787219ENST0000042178202366_3700136.0MotifNuclear localization signal
TgeneRAD51Cchr17:7797253chr17:56787220ENST0000033743239366_370235.0377.0MotifNuclear localization signal
TgeneRAD51Cchr17:7797253chr17:56787220ENST0000042178202366_3700136.0MotifNuclear localization signal
TgeneRAD51Cchr17:7797253chr17:56787219ENST0000042178202125_1320136.0Nucleotide bindingATP
TgeneRAD51Cchr17:7797253chr17:56787220ENST0000042178202125_1320136.0Nucleotide bindingATP
TgeneRAD51Cchr17:7797253chr17:56787219ENST00000421782021_1260136.0RegionNote=Required for Holliday junction resolution activity
TgeneRAD51Cchr17:7797253chr17:56787220ENST00000421782021_1260136.0RegionNote=Required for Holliday junction resolution activity

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640355_358308.02001.0Compositional biasNote=Poly-Lys
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640434_446308.02001.0Compositional biasNote=Poly-Glu
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640697_703308.02001.0Compositional biasNote=Poly-Lys
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639355_358308.01967.0Compositional biasNote=Poly-Lys
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639434_446308.01967.0Compositional biasNote=Poly-Glu
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639697_703308.01967.0Compositional biasNote=Poly-Lys
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640434_446367.02060.0Compositional biasNote=Poly-Glu
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640697_703367.02060.0Compositional biasNote=Poly-Lys
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640355_358308.02001.0Compositional biasNote=Poly-Lys
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640434_446308.02001.0Compositional biasNote=Poly-Glu
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640697_703308.02001.0Compositional biasNote=Poly-Lys
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639355_358308.01967.0Compositional biasNote=Poly-Lys
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639434_446308.01967.0Compositional biasNote=Poly-Glu
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639697_703308.01967.0Compositional biasNote=Poly-Lys
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640434_446367.02060.0Compositional biasNote=Poly-Glu
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640697_703367.02060.0Compositional biasNote=Poly-Lys
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+6401064_1229308.02001.0DomainHelicase C-terminal
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640494_594308.02001.0DomainChromo 1
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640631_673308.02001.0DomainChromo 2
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640748_932308.02001.0DomainHelicase ATP-binding
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+6391064_1229308.01967.0DomainHelicase C-terminal
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639494_594308.01967.0DomainChromo 1
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639631_673308.01967.0DomainChromo 2
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639748_932308.01967.0DomainHelicase ATP-binding
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+6401064_1229367.02060.0DomainHelicase C-terminal
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640494_594367.02060.0DomainChromo 1
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640631_673367.02060.0DomainChromo 2
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640748_932367.02060.0DomainHelicase ATP-binding
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+6401064_1229308.02001.0DomainHelicase C-terminal
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640494_594308.02001.0DomainChromo 1
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640631_673308.02001.0DomainChromo 2
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640748_932308.02001.0DomainHelicase ATP-binding
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+6391064_1229308.01967.0DomainHelicase C-terminal
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639494_594308.01967.0DomainChromo 1
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639631_673308.01967.0DomainChromo 2
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639748_932308.01967.0DomainHelicase ATP-binding
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+6401064_1229367.02060.0DomainHelicase C-terminal
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640494_594367.02060.0DomainChromo 1
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640631_673367.02060.0DomainChromo 2
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640748_932367.02060.0DomainHelicase ATP-binding
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640883_886308.02001.0MotifNote=DEAH box
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639883_886308.01967.0MotifNote=DEAH box
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640883_886367.02060.0MotifNote=DEAH box
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640883_886308.02001.0MotifNote=DEAH box
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639883_886308.01967.0MotifNote=DEAH box
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640883_886367.02060.0MotifNote=DEAH box
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640761_768308.02001.0Nucleotide bindingATP
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639761_768308.01967.0Nucleotide bindingATP
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640761_768367.02060.0Nucleotide bindingATP
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640761_768308.02001.0Nucleotide bindingATP
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639761_768308.01967.0Nucleotide bindingATP
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640761_768367.02060.0Nucleotide bindingATP
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640379_426308.02001.0Zinc fingerPHD-type 1
HgeneCHD3chr17:7797253chr17:56787219ENST00000330494+640456_503308.02001.0Zinc fingerPHD-type 2
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639379_426308.01967.0Zinc fingerPHD-type 1
HgeneCHD3chr17:7797253chr17:56787219ENST00000358181+639456_503308.01967.0Zinc fingerPHD-type 2
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640379_426367.02060.0Zinc fingerPHD-type 1
HgeneCHD3chr17:7797253chr17:56787219ENST00000380358+640456_503367.02060.0Zinc fingerPHD-type 2
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640379_426308.02001.0Zinc fingerPHD-type 1
HgeneCHD3chr17:7797253chr17:56787220ENST00000330494+640456_503308.02001.0Zinc fingerPHD-type 2
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639379_426308.01967.0Zinc fingerPHD-type 1
HgeneCHD3chr17:7797253chr17:56787220ENST00000358181+639456_503308.01967.0Zinc fingerPHD-type 2
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640379_426367.02060.0Zinc fingerPHD-type 1
HgeneCHD3chr17:7797253chr17:56787220ENST00000380358+640456_503367.02060.0Zinc fingerPHD-type 2
TgeneRAD51Cchr17:7797253chr17:56787219ENST0000033743239125_132235.0377.0Nucleotide bindingATP
TgeneRAD51Cchr17:7797253chr17:56787220ENST0000033743239125_132235.0377.0Nucleotide bindingATP
TgeneRAD51Cchr17:7797253chr17:56787219ENST00000337432391_126235.0377.0RegionNote=Required for Holliday junction resolution activity
TgeneRAD51Cchr17:7797253chr17:56787220ENST00000337432391_126235.0377.0RegionNote=Required for Holliday junction resolution activity


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Fusion Gene Sequence for CHD3-RAD51C


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000380358_ENST00000583539_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(transcript)=1645nt_BP=1102nt
GATGGCTTCCCCTCTGAGGGACGAGGAGGAGGAGGAGGAGGAGATGGTGGTGTCGGAGGAGGAAGAAGAGGAGGAAGAAGAGGGCGACGA
GGAGGAGGAGGAGGAGGTGGAGGCGGCCGACGAGGACGATGAGGAGGACGACGACGAGGGAGTACTCGGGCGCGGGCCGGGCCACGACCG
GGGCCGCGACCGCCACAGCCCCCCCGGCTGCCACCTCTTCCCGCCGCCGCCGCCGCCGCCGCCACCGCTGCCCCCGCCGCCGCCGCCCCC
GCCGCCAGATAAGGATGACATTCGGCTGCTGCCGTCAGCATTGGGTGTGAAGAAGAGAAAACGAGGACCCAAGAAGCAGAAGGAGAACAA
GCCAGGAAAACCCCGAAAACGCAAGAAGCGTGACAGTGAGGAGGAATTTGGTTCTGAGCGAGATGAGTACCGGGAGAAGTCAGAGAGTGG
GGGCAGTGAATATGGAACCGGACCGGGTCGGAAACGAAGAAGGAAGCACCGAGAAAAAAAGGAGAAGAAGACAAAGCGGCGGAAAAAGGG
GGAGGGAGATGGGGGGCAAAAGCAAGTGGAACAGAAGTCATCAGCAACTCTGCTTCTGACCTGGGGCCTGGAGGATGTGGAGCATGTGTT
CTCTGAGGAGGATTACCACACGCTCACCAACTACAAAGCCTTCAGCCAGTTCATGAGGCCCCTAATTGCTAAGAAGAATCCTAAGATCCC
AATGTCTAAGATGATGACCATCCTTGGGGCCAAATGGAGAGAGTTCAGTGCCAACAACCCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGC
GGCAGCGGCAGCAGCAGCAGCAGCTGTAGCTGAGCAGGTGTCAGCTGCTGTCTCGTCGGCCACCCCCATAGCACCCTCCGGACCCCCCGC
CCTTCCACCACCCCCTGCTGCTGATATCCAGCCCCCACCCATCCGAAGAGCCAAAACCAAAGAGGGCAAAGGTCCAGGCCATAAGAGGCG
GAGTAAGAGCCCCCGAGTGCCTGATGGACGCAAGAAGCTTCGGGGAAAGAAAATGGCACCACTCAAAATAAAACTAGGGCTTCTGGGTGG
CAAGAGGAAGAAAGGAGGCTCGGTTCGACTAGTGATAGTGGATGGTATTGCTTTTCCATTTCGTCATGACCTAGATGACCTGTCTCTTCG
TACTCGGTTATTAAATGGCCTAGCCCAGCAAATGATCAGCCTTGCAAATAATCACAGATTAGCTGTAATTTTAACCAATCAGATGACAAC
AAAGATTGATAGAAATCAGGCCTTGCTTGTTCCTGCATTAGGGGAAAGTTGGGGACATGCTGCTACAATACGGCTAATCTTTCATTGGGA
CCGAAAGCAAAGGTTGGCAACATTGTACAAGTCACCCAGCCAGAAGGAATGCACAGTACTGTTTCAAATCAAAGTCAGTATTATTTGATT
AGAGTGGGATTTTGATATTGATGGGCGGTAATTATCTAAAGAGAGAATTTACAACTTGCTTCTGTCAACTTCTGTAGGCAGCAAGCATAT
TTGAGGACAGCTTTTGATGCTTAGAACATTGTCCCCAAAATAGTAGTATATACAGAATATTGTAGTCACAAATGGACTGAAATTTATTCT

>In-frame_ENST00000380358_ENST00000583539_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(amino acids)=478AA_start in transcript=1_stop in transcript=1437
MASPLRDEEEEEEEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHDRGRDRHSPPGCHLFPPPPPPPPPLPPPPPPP
PPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKG
EGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPMSKMMTILGAKWREFSANNPFKGSAAAVAA
AAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGG
KRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALLVPALGESWGHAATIRLIFHWD

--------------------------------------------------------------
>In-frame_ENST00000380358_ENST00000337432_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(transcript)=1648nt_BP=1102nt
GATGGCTTCCCCTCTGAGGGACGAGGAGGAGGAGGAGGAGGAGATGGTGGTGTCGGAGGAGGAAGAAGAGGAGGAAGAAGAGGGCGACGA
GGAGGAGGAGGAGGAGGTGGAGGCGGCCGACGAGGACGATGAGGAGGACGACGACGAGGGAGTACTCGGGCGCGGGCCGGGCCACGACCG
GGGCCGCGACCGCCACAGCCCCCCCGGCTGCCACCTCTTCCCGCCGCCGCCGCCGCCGCCGCCACCGCTGCCCCCGCCGCCGCCGCCCCC
GCCGCCAGATAAGGATGACATTCGGCTGCTGCCGTCAGCATTGGGTGTGAAGAAGAGAAAACGAGGACCCAAGAAGCAGAAGGAGAACAA
GCCAGGAAAACCCCGAAAACGCAAGAAGCGTGACAGTGAGGAGGAATTTGGTTCTGAGCGAGATGAGTACCGGGAGAAGTCAGAGAGTGG
GGGCAGTGAATATGGAACCGGACCGGGTCGGAAACGAAGAAGGAAGCACCGAGAAAAAAAGGAGAAGAAGACAAAGCGGCGGAAAAAGGG
GGAGGGAGATGGGGGGCAAAAGCAAGTGGAACAGAAGTCATCAGCAACTCTGCTTCTGACCTGGGGCCTGGAGGATGTGGAGCATGTGTT
CTCTGAGGAGGATTACCACACGCTCACCAACTACAAAGCCTTCAGCCAGTTCATGAGGCCCCTAATTGCTAAGAAGAATCCTAAGATCCC
AATGTCTAAGATGATGACCATCCTTGGGGCCAAATGGAGAGAGTTCAGTGCCAACAACCCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGC
GGCAGCGGCAGCAGCAGCAGCAGCTGTAGCTGAGCAGGTGTCAGCTGCTGTCTCGTCGGCCACCCCCATAGCACCCTCCGGACCCCCCGC
CCTTCCACCACCCCCTGCTGCTGATATCCAGCCCCCACCCATCCGAAGAGCCAAAACCAAAGAGGGCAAAGGTCCAGGCCATAAGAGGCG
GAGTAAGAGCCCCCGAGTGCCTGATGGACGCAAGAAGCTTCGGGGAAAGAAAATGGCACCACTCAAAATAAAACTAGGGCTTCTGGGTGG
CAAGAGGAAGAAAGGAGGCTCGGTTCGACTAGTGATAGTGGATGGTATTGCTTTTCCATTTCGTCATGACCTAGATGACCTGTCTCTTCG
TACTCGGTTATTAAATGGCCTAGCCCAGCAAATGATCAGCCTTGCAAATAATCACAGATTAGCTGTAATTTTAACCAATCAGATGACAAC
AAAGATTGATAGAAATCAGGCCTTGCTTGTTCCTGCATTAGGGGAAAGTTGGGGACATGCTGCTACAATACGGCTAATCTTTCATTGGGA
CCGAAAGCAAAGGTTGGCAACATTGTACAAGTCACCCAGCCAGAAGGAATGCACAGTACTGTTTCAAATCAAACCTCAGGGATTTAGAGA
TACTGTTGTTACTTCTGCATGTTCATTGCAAACAGAAGGTTCCTTGAGCACCCGGAAACGGTCACGAGACCCAGAGGAAGAATTATAACC
CAGAAACAAATCTCAAAGTGTACAAATTTATTGATGTTGTGAAATCAATGTGTACAAGTGGACTTGTTACCTTAAAGTATAAATAAACAC

>In-frame_ENST00000380358_ENST00000337432_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(amino acids)=508AA_start in transcript=1_stop in transcript=1527
MASPLRDEEEEEEEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHDRGRDRHSPPGCHLFPPPPPPPPPLPPPPPPP
PPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKG
EGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPMSKMMTILGAKWREFSANNPFKGSAAAVAA
AAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGG
KRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALLVPALGESWGHAATIRLIFHWD

--------------------------------------------------------------
>In-frame_ENST00000358181_ENST00000583539_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(transcript)=1677nt_BP=1134nt
ATCTTTGTTTGGGTCTCCCATACTGCGTATAGATGAATGGGTCAGGATATCTGGAACAAAATATGGAGGTGAAGGGTGAGATCGGGAAAC
AAAGGGTATGGCCCCCTAGTTCCCAAAGGGAGCAGGGAGATGGGAATAGAATTGAAGGTAGGTTTTAGGCTACTTGGGAGGAGGAATATT
TAGGTAATTGTGGAGACTTTCTCCTGTGTGATGAAGGCGGCAGACACTGTGATCCTGTGGGCAAGAAGTAAAAATGACCAGCTGAGGATT
TCTTTTCCTCCAGGACTGTGTTGGGGTGACAGGATGCCTGATAAGGATGACATTCGGCTGCTGCCGTCAGCATTGGGTGTGAAGAAGAGA
AAACGAGGACCCAAGAAGCAGAAGGAGAACAAGCCAGGAAAACCCCGAAAACGCAAGAAGCGTGACAGTGAGGAGGAATTTGGTTCTGAG
CGAGATGAGTACCGGGAGAAGTCAGAGAGTGGGGGCAGTGAATATGGAACCGGACCGGGTCGGAAACGAAGAAGGAAGCACCGAGAAAAA
AAGGAGAAGAAGACAAAGCGGCGGAAAAAGGGGGAGGGAGATGGGGGGCAAAAGCAAGTGGAACAGAAGTCATCAGCAACTCTGCTTCTG
ACCTGGGGCCTGGAGGATGTGGAGCATGTGTTCTCTGAGGAGGATTACCACACGCTCACCAACTACAAAGCCTTCAGCCAGTTCATGAGG
CCCCTAATTGCTAAGAAGAATCCTAAGATCCCAATGTCTAAGATGATGACCATCCTTGGGGCCAAATGGAGAGAGTTCAGTGCCAACAAC
CCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGCGGCAGCGGCAGCAGCAGCAGCAGCTGTAGCTGAGCAGGTGTCAGCTGCTGTCTCGTCG
GCCACCCCCATAGCACCCTCCGGACCCCCCGCCCTTCCACCACCCCCTGCTGCTGATATCCAGCCCCCACCCATCCGAAGAGCCAAAACC
AAAGAGGGCAAAGGTCCAGGCCATAAGAGGCGGAGTAAGAGCCCCCGAGTGCCTGATGGACGCAAGAAGCTTCGGGGAAAGAAAATGGCA
CCACTCAAAATAAAACTAGGGCTTCTGGGTGGCAAGAGGAAGAAAGGAGGCTCGGTTCGACTAGTGATAGTGGATGGTATTGCTTTTCCA
TTTCGTCATGACCTAGATGACCTGTCTCTTCGTACTCGGTTATTAAATGGCCTAGCCCAGCAAATGATCAGCCTTGCAAATAATCACAGA
TTAGCTGTAATTTTAACCAATCAGATGACAACAAAGATTGATAGAAATCAGGCCTTGCTTGTTCCTGCATTAGGGGAAAGTTGGGGACAT
GCTGCTACAATACGGCTAATCTTTCATTGGGACCGAAAGCAAAGGTTGGCAACATTGTACAAGTCACCCAGCCAGAAGGAATGCACAGTA
CTGTTTCAAATCAAAGTCAGTATTATTTGATTAGAGTGGGATTTTGATATTGATGGGCGGTAATTATCTAAAGAGAGAATTTACAACTTG
CTTCTGTCAACTTCTGTAGGCAGCAAGCATATTTGAGGACAGCTTTTGATGCTTAGAACATTGTCCCCAAAATAGTAGTATATACAGAAT

>In-frame_ENST00000358181_ENST00000583539_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(amino acids)=419AA_start in transcript=210_stop in transcript=1469
MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSES
GGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKR
RSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMT

--------------------------------------------------------------
>In-frame_ENST00000358181_ENST00000337432_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(transcript)=1680nt_BP=1134nt
ATCTTTGTTTGGGTCTCCCATACTGCGTATAGATGAATGGGTCAGGATATCTGGAACAAAATATGGAGGTGAAGGGTGAGATCGGGAAAC
AAAGGGTATGGCCCCCTAGTTCCCAAAGGGAGCAGGGAGATGGGAATAGAATTGAAGGTAGGTTTTAGGCTACTTGGGAGGAGGAATATT
TAGGTAATTGTGGAGACTTTCTCCTGTGTGATGAAGGCGGCAGACACTGTGATCCTGTGGGCAAGAAGTAAAAATGACCAGCTGAGGATT
TCTTTTCCTCCAGGACTGTGTTGGGGTGACAGGATGCCTGATAAGGATGACATTCGGCTGCTGCCGTCAGCATTGGGTGTGAAGAAGAGA
AAACGAGGACCCAAGAAGCAGAAGGAGAACAAGCCAGGAAAACCCCGAAAACGCAAGAAGCGTGACAGTGAGGAGGAATTTGGTTCTGAG
CGAGATGAGTACCGGGAGAAGTCAGAGAGTGGGGGCAGTGAATATGGAACCGGACCGGGTCGGAAACGAAGAAGGAAGCACCGAGAAAAA
AAGGAGAAGAAGACAAAGCGGCGGAAAAAGGGGGAGGGAGATGGGGGGCAAAAGCAAGTGGAACAGAAGTCATCAGCAACTCTGCTTCTG
ACCTGGGGCCTGGAGGATGTGGAGCATGTGTTCTCTGAGGAGGATTACCACACGCTCACCAACTACAAAGCCTTCAGCCAGTTCATGAGG
CCCCTAATTGCTAAGAAGAATCCTAAGATCCCAATGTCTAAGATGATGACCATCCTTGGGGCCAAATGGAGAGAGTTCAGTGCCAACAAC
CCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGCGGCAGCGGCAGCAGCAGCAGCAGCTGTAGCTGAGCAGGTGTCAGCTGCTGTCTCGTCG
GCCACCCCCATAGCACCCTCCGGACCCCCCGCCCTTCCACCACCCCCTGCTGCTGATATCCAGCCCCCACCCATCCGAAGAGCCAAAACC
AAAGAGGGCAAAGGTCCAGGCCATAAGAGGCGGAGTAAGAGCCCCCGAGTGCCTGATGGACGCAAGAAGCTTCGGGGAAAGAAAATGGCA
CCACTCAAAATAAAACTAGGGCTTCTGGGTGGCAAGAGGAAGAAAGGAGGCTCGGTTCGACTAGTGATAGTGGATGGTATTGCTTTTCCA
TTTCGTCATGACCTAGATGACCTGTCTCTTCGTACTCGGTTATTAAATGGCCTAGCCCAGCAAATGATCAGCCTTGCAAATAATCACAGA
TTAGCTGTAATTTTAACCAATCAGATGACAACAAAGATTGATAGAAATCAGGCCTTGCTTGTTCCTGCATTAGGGGAAAGTTGGGGACAT
GCTGCTACAATACGGCTAATCTTTCATTGGGACCGAAAGCAAAGGTTGGCAACATTGTACAAGTCACCCAGCCAGAAGGAATGCACAGTA
CTGTTTCAAATCAAACCTCAGGGATTTAGAGATACTGTTGTTACTTCTGCATGTTCATTGCAAACAGAAGGTTCCTTGAGCACCCGGAAA
CGGTCACGAGACCCAGAGGAAGAATTATAACCCAGAAACAAATCTCAAAGTGTACAAATTTATTGATGTTGTGAAATCAATGTGTACAAG

>In-frame_ENST00000358181_ENST00000337432_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(amino acids)=449AA_start in transcript=210_stop in transcript=1559
MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSES
GGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKR
RSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMT

--------------------------------------------------------------
>In-frame_ENST00000330494_ENST00000583539_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(transcript)=1617nt_BP=1074nt
ATATGGAGGTGAAGGGTGAGATCGGGAAACAAAGGGTATGGCCCCCTAGTTCCCAAAGGGAGCAGGGAGATGGGAATAGAATTGAAGGTA
GGTTTTAGGCTACTTGGGAGGAGGAATATTTAGGTAATTGTGGAGACTTTCTCCTGTGTGATGAAGGCGGCAGACACTGTGATCCTGTGG
GCAAGAAGTAAAAATGACCAGCTGAGGATTTCTTTTCCTCCAGGACTGTGTTGGGGTGACAGGATGCCTGATAAGGATGACATTCGGCTG
CTGCCGTCAGCATTGGGTGTGAAGAAGAGAAAACGAGGACCCAAGAAGCAGAAGGAGAACAAGCCAGGAAAACCCCGAAAACGCAAGAAG
CGTGACAGTGAGGAGGAATTTGGTTCTGAGCGAGATGAGTACCGGGAGAAGTCAGAGAGTGGGGGCAGTGAATATGGAACCGGACCGGGT
CGGAAACGAAGAAGGAAGCACCGAGAAAAAAAGGAGAAGAAGACAAAGCGGCGGAAAAAGGGGGAGGGAGATGGGGGGCAAAAGCAAGTG
GAACAGAAGTCATCAGCAACTCTGCTTCTGACCTGGGGCCTGGAGGATGTGGAGCATGTGTTCTCTGAGGAGGATTACCACACGCTCACC
AACTACAAAGCCTTCAGCCAGTTCATGAGGCCCCTAATTGCTAAGAAGAATCCTAAGATCCCAATGTCTAAGATGATGACCATCCTTGGG
GCCAAATGGAGAGAGTTCAGTGCCAACAACCCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGCGGCAGCGGCAGCAGCAGCAGCAGCTGTA
GCTGAGCAGGTGTCAGCTGCTGTCTCGTCGGCCACCCCCATAGCACCCTCCGGACCCCCCGCCCTTCCACCACCCCCTGCTGCTGATATC
CAGCCCCCACCCATCCGAAGAGCCAAAACCAAAGAGGGCAAAGGTCCAGGCCATAAGAGGCGGAGTAAGAGCCCCCGAGTGCCTGATGGA
CGCAAGAAGCTTCGGGGAAAGAAAATGGCACCACTCAAAATAAAACTAGGGCTTCTGGGTGGCAAGAGGAAGAAAGGAGGCTCGGTTCGA
CTAGTGATAGTGGATGGTATTGCTTTTCCATTTCGTCATGACCTAGATGACCTGTCTCTTCGTACTCGGTTATTAAATGGCCTAGCCCAG
CAAATGATCAGCCTTGCAAATAATCACAGATTAGCTGTAATTTTAACCAATCAGATGACAACAAAGATTGATAGAAATCAGGCCTTGCTT
GTTCCTGCATTAGGGGAAAGTTGGGGACATGCTGCTACAATACGGCTAATCTTTCATTGGGACCGAAAGCAAAGGTTGGCAACATTGTAC
AAGTCACCCAGCCAGAAGGAATGCACAGTACTGTTTCAAATCAAAGTCAGTATTATTTGATTAGAGTGGGATTTTGATATTGATGGGCGG
TAATTATCTAAAGAGAGAATTTACAACTTGCTTCTGTCAACTTCTGTAGGCAGCAAGCATATTTGAGGACAGCTTTTGATGCTTAGAACA

>In-frame_ENST00000330494_ENST00000583539_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(amino acids)=419AA_start in transcript=150_stop in transcript=1409
MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSES
GGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKR
RSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMT

--------------------------------------------------------------
>In-frame_ENST00000330494_ENST00000337432_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(transcript)=1620nt_BP=1074nt
ATATGGAGGTGAAGGGTGAGATCGGGAAACAAAGGGTATGGCCCCCTAGTTCCCAAAGGGAGCAGGGAGATGGGAATAGAATTGAAGGTA
GGTTTTAGGCTACTTGGGAGGAGGAATATTTAGGTAATTGTGGAGACTTTCTCCTGTGTGATGAAGGCGGCAGACACTGTGATCCTGTGG
GCAAGAAGTAAAAATGACCAGCTGAGGATTTCTTTTCCTCCAGGACTGTGTTGGGGTGACAGGATGCCTGATAAGGATGACATTCGGCTG
CTGCCGTCAGCATTGGGTGTGAAGAAGAGAAAACGAGGACCCAAGAAGCAGAAGGAGAACAAGCCAGGAAAACCCCGAAAACGCAAGAAG
CGTGACAGTGAGGAGGAATTTGGTTCTGAGCGAGATGAGTACCGGGAGAAGTCAGAGAGTGGGGGCAGTGAATATGGAACCGGACCGGGT
CGGAAACGAAGAAGGAAGCACCGAGAAAAAAAGGAGAAGAAGACAAAGCGGCGGAAAAAGGGGGAGGGAGATGGGGGGCAAAAGCAAGTG
GAACAGAAGTCATCAGCAACTCTGCTTCTGACCTGGGGCCTGGAGGATGTGGAGCATGTGTTCTCTGAGGAGGATTACCACACGCTCACC
AACTACAAAGCCTTCAGCCAGTTCATGAGGCCCCTAATTGCTAAGAAGAATCCTAAGATCCCAATGTCTAAGATGATGACCATCCTTGGG
GCCAAATGGAGAGAGTTCAGTGCCAACAACCCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGCGGCAGCGGCAGCAGCAGCAGCAGCTGTA
GCTGAGCAGGTGTCAGCTGCTGTCTCGTCGGCCACCCCCATAGCACCCTCCGGACCCCCCGCCCTTCCACCACCCCCTGCTGCTGATATC
CAGCCCCCACCCATCCGAAGAGCCAAAACCAAAGAGGGCAAAGGTCCAGGCCATAAGAGGCGGAGTAAGAGCCCCCGAGTGCCTGATGGA
CGCAAGAAGCTTCGGGGAAAGAAAATGGCACCACTCAAAATAAAACTAGGGCTTCTGGGTGGCAAGAGGAAGAAAGGAGGCTCGGTTCGA
CTAGTGATAGTGGATGGTATTGCTTTTCCATTTCGTCATGACCTAGATGACCTGTCTCTTCGTACTCGGTTATTAAATGGCCTAGCCCAG
CAAATGATCAGCCTTGCAAATAATCACAGATTAGCTGTAATTTTAACCAATCAGATGACAACAAAGATTGATAGAAATCAGGCCTTGCTT
GTTCCTGCATTAGGGGAAAGTTGGGGACATGCTGCTACAATACGGCTAATCTTTCATTGGGACCGAAAGCAAAGGTTGGCAACATTGTAC
AAGTCACCCAGCCAGAAGGAATGCACAGTACTGTTTCAAATCAAACCTCAGGGATTTAGAGATACTGTTGTTACTTCTGCATGTTCATTG
CAAACAGAAGGTTCCTTGAGCACCCGGAAACGGTCACGAGACCCAGAGGAAGAATTATAACCCAGAAACAAATCTCAAAGTGTACAAATT
TATTGATGTTGTGAAATCAATGTGTACAAGTGGACTTGTTACCTTAAAGTATAAATAAACACACTATGGCATGAATGAATCCAGATCATA

>In-frame_ENST00000330494_ENST00000337432_TCGA-OR-A5KY-01A_CHD3_chr17_7797253_+_RAD51C_chr17_56787220_length(amino acids)=449AA_start in transcript=150_stop in transcript=1499
MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSES
GGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKR
RSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMT

--------------------------------------------------------------
>In-frame_ENST00000380358_ENST00000583539_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(transcript)=1645nt_BP=1102nt
GATGGCTTCCCCTCTGAGGGACGAGGAGGAGGAGGAGGAGGAGATGGTGGTGTCGGAGGAGGAAGAAGAGGAGGAAGAAGAGGGCGACGA
GGAGGAGGAGGAGGAGGTGGAGGCGGCCGACGAGGACGATGAGGAGGACGACGACGAGGGAGTACTCGGGCGCGGGCCGGGCCACGACCG
GGGCCGCGACCGCCACAGCCCCCCCGGCTGCCACCTCTTCCCGCCGCCGCCGCCGCCGCCGCCACCGCTGCCCCCGCCGCCGCCGCCCCC
GCCGCCAGATAAGGATGACATTCGGCTGCTGCCGTCAGCATTGGGTGTGAAGAAGAGAAAACGAGGACCCAAGAAGCAGAAGGAGAACAA
GCCAGGAAAACCCCGAAAACGCAAGAAGCGTGACAGTGAGGAGGAATTTGGTTCTGAGCGAGATGAGTACCGGGAGAAGTCAGAGAGTGG
GGGCAGTGAATATGGAACCGGACCGGGTCGGAAACGAAGAAGGAAGCACCGAGAAAAAAAGGAGAAGAAGACAAAGCGGCGGAAAAAGGG
GGAGGGAGATGGGGGGCAAAAGCAAGTGGAACAGAAGTCATCAGCAACTCTGCTTCTGACCTGGGGCCTGGAGGATGTGGAGCATGTGTT
CTCTGAGGAGGATTACCACACGCTCACCAACTACAAAGCCTTCAGCCAGTTCATGAGGCCCCTAATTGCTAAGAAGAATCCTAAGATCCC
AATGTCTAAGATGATGACCATCCTTGGGGCCAAATGGAGAGAGTTCAGTGCCAACAACCCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGC
GGCAGCGGCAGCAGCAGCAGCAGCTGTAGCTGAGCAGGTGTCAGCTGCTGTCTCGTCGGCCACCCCCATAGCACCCTCCGGACCCCCCGC
CCTTCCACCACCCCCTGCTGCTGATATCCAGCCCCCACCCATCCGAAGAGCCAAAACCAAAGAGGGCAAAGGTCCAGGCCATAAGAGGCG
GAGTAAGAGCCCCCGAGTGCCTGATGGACGCAAGAAGCTTCGGGGAAAGAAAATGGCACCACTCAAAATAAAACTAGGGCTTCTGGGTGG
CAAGAGGAAGAAAGGAGGCTCGGTTCGACTAGTGATAGTGGATGGTATTGCTTTTCCATTTCGTCATGACCTAGATGACCTGTCTCTTCG
TACTCGGTTATTAAATGGCCTAGCCCAGCAAATGATCAGCCTTGCAAATAATCACAGATTAGCTGTAATTTTAACCAATCAGATGACAAC
AAAGATTGATAGAAATCAGGCCTTGCTTGTTCCTGCATTAGGGGAAAGTTGGGGACATGCTGCTACAATACGGCTAATCTTTCATTGGGA
CCGAAAGCAAAGGTTGGCAACATTGTACAAGTCACCCAGCCAGAAGGAATGCACAGTACTGTTTCAAATCAAAGTCAGTATTATTTGATT
AGAGTGGGATTTTGATATTGATGGGCGGTAATTATCTAAAGAGAGAATTTACAACTTGCTTCTGTCAACTTCTGTAGGCAGCAAGCATAT
TTGAGGACAGCTTTTGATGCTTAGAACATTGTCCCCAAAATAGTAGTATATACAGAATATTGTAGTCACAAATGGACTGAAATTTATTCT

>In-frame_ENST00000380358_ENST00000583539_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(amino acids)=478AA_start in transcript=1_stop in transcript=1437
MASPLRDEEEEEEEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHDRGRDRHSPPGCHLFPPPPPPPPPLPPPPPPP
PPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKG
EGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPMSKMMTILGAKWREFSANNPFKGSAAAVAA
AAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGG
KRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALLVPALGESWGHAATIRLIFHWD

--------------------------------------------------------------
>In-frame_ENST00000380358_ENST00000337432_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(transcript)=1648nt_BP=1102nt
GATGGCTTCCCCTCTGAGGGACGAGGAGGAGGAGGAGGAGGAGATGGTGGTGTCGGAGGAGGAAGAAGAGGAGGAAGAAGAGGGCGACGA
GGAGGAGGAGGAGGAGGTGGAGGCGGCCGACGAGGACGATGAGGAGGACGACGACGAGGGAGTACTCGGGCGCGGGCCGGGCCACGACCG
GGGCCGCGACCGCCACAGCCCCCCCGGCTGCCACCTCTTCCCGCCGCCGCCGCCGCCGCCGCCACCGCTGCCCCCGCCGCCGCCGCCCCC
GCCGCCAGATAAGGATGACATTCGGCTGCTGCCGTCAGCATTGGGTGTGAAGAAGAGAAAACGAGGACCCAAGAAGCAGAAGGAGAACAA
GCCAGGAAAACCCCGAAAACGCAAGAAGCGTGACAGTGAGGAGGAATTTGGTTCTGAGCGAGATGAGTACCGGGAGAAGTCAGAGAGTGG
GGGCAGTGAATATGGAACCGGACCGGGTCGGAAACGAAGAAGGAAGCACCGAGAAAAAAAGGAGAAGAAGACAAAGCGGCGGAAAAAGGG
GGAGGGAGATGGGGGGCAAAAGCAAGTGGAACAGAAGTCATCAGCAACTCTGCTTCTGACCTGGGGCCTGGAGGATGTGGAGCATGTGTT
CTCTGAGGAGGATTACCACACGCTCACCAACTACAAAGCCTTCAGCCAGTTCATGAGGCCCCTAATTGCTAAGAAGAATCCTAAGATCCC
AATGTCTAAGATGATGACCATCCTTGGGGCCAAATGGAGAGAGTTCAGTGCCAACAACCCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGC
GGCAGCGGCAGCAGCAGCAGCAGCTGTAGCTGAGCAGGTGTCAGCTGCTGTCTCGTCGGCCACCCCCATAGCACCCTCCGGACCCCCCGC
CCTTCCACCACCCCCTGCTGCTGATATCCAGCCCCCACCCATCCGAAGAGCCAAAACCAAAGAGGGCAAAGGTCCAGGCCATAAGAGGCG
GAGTAAGAGCCCCCGAGTGCCTGATGGACGCAAGAAGCTTCGGGGAAAGAAAATGGCACCACTCAAAATAAAACTAGGGCTTCTGGGTGG
CAAGAGGAAGAAAGGAGGCTCGGTTCGACTAGTGATAGTGGATGGTATTGCTTTTCCATTTCGTCATGACCTAGATGACCTGTCTCTTCG
TACTCGGTTATTAAATGGCCTAGCCCAGCAAATGATCAGCCTTGCAAATAATCACAGATTAGCTGTAATTTTAACCAATCAGATGACAAC
AAAGATTGATAGAAATCAGGCCTTGCTTGTTCCTGCATTAGGGGAAAGTTGGGGACATGCTGCTACAATACGGCTAATCTTTCATTGGGA
CCGAAAGCAAAGGTTGGCAACATTGTACAAGTCACCCAGCCAGAAGGAATGCACAGTACTGTTTCAAATCAAACCTCAGGGATTTAGAGA
TACTGTTGTTACTTCTGCATGTTCATTGCAAACAGAAGGTTCCTTGAGCACCCGGAAACGGTCACGAGACCCAGAGGAAGAATTATAACC
CAGAAACAAATCTCAAAGTGTACAAATTTATTGATGTTGTGAAATCAATGTGTACAAGTGGACTTGTTACCTTAAAGTATAAATAAACAC

>In-frame_ENST00000380358_ENST00000337432_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(amino acids)=508AA_start in transcript=1_stop in transcript=1527
MASPLRDEEEEEEEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHDRGRDRHSPPGCHLFPPPPPPPPPLPPPPPPP
PPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKG
EGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPMSKMMTILGAKWREFSANNPFKGSAAAVAA
AAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGG
KRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALLVPALGESWGHAATIRLIFHWD

--------------------------------------------------------------
>In-frame_ENST00000358181_ENST00000583539_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(transcript)=1677nt_BP=1134nt
ATCTTTGTTTGGGTCTCCCATACTGCGTATAGATGAATGGGTCAGGATATCTGGAACAAAATATGGAGGTGAAGGGTGAGATCGGGAAAC
AAAGGGTATGGCCCCCTAGTTCCCAAAGGGAGCAGGGAGATGGGAATAGAATTGAAGGTAGGTTTTAGGCTACTTGGGAGGAGGAATATT
TAGGTAATTGTGGAGACTTTCTCCTGTGTGATGAAGGCGGCAGACACTGTGATCCTGTGGGCAAGAAGTAAAAATGACCAGCTGAGGATT
TCTTTTCCTCCAGGACTGTGTTGGGGTGACAGGATGCCTGATAAGGATGACATTCGGCTGCTGCCGTCAGCATTGGGTGTGAAGAAGAGA
AAACGAGGACCCAAGAAGCAGAAGGAGAACAAGCCAGGAAAACCCCGAAAACGCAAGAAGCGTGACAGTGAGGAGGAATTTGGTTCTGAG
CGAGATGAGTACCGGGAGAAGTCAGAGAGTGGGGGCAGTGAATATGGAACCGGACCGGGTCGGAAACGAAGAAGGAAGCACCGAGAAAAA
AAGGAGAAGAAGACAAAGCGGCGGAAAAAGGGGGAGGGAGATGGGGGGCAAAAGCAAGTGGAACAGAAGTCATCAGCAACTCTGCTTCTG
ACCTGGGGCCTGGAGGATGTGGAGCATGTGTTCTCTGAGGAGGATTACCACACGCTCACCAACTACAAAGCCTTCAGCCAGTTCATGAGG
CCCCTAATTGCTAAGAAGAATCCTAAGATCCCAATGTCTAAGATGATGACCATCCTTGGGGCCAAATGGAGAGAGTTCAGTGCCAACAAC
CCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGCGGCAGCGGCAGCAGCAGCAGCAGCTGTAGCTGAGCAGGTGTCAGCTGCTGTCTCGTCG
GCCACCCCCATAGCACCCTCCGGACCCCCCGCCCTTCCACCACCCCCTGCTGCTGATATCCAGCCCCCACCCATCCGAAGAGCCAAAACC
AAAGAGGGCAAAGGTCCAGGCCATAAGAGGCGGAGTAAGAGCCCCCGAGTGCCTGATGGACGCAAGAAGCTTCGGGGAAAGAAAATGGCA
CCACTCAAAATAAAACTAGGGCTTCTGGGTGGCAAGAGGAAGAAAGGAGGCTCGGTTCGACTAGTGATAGTGGATGGTATTGCTTTTCCA
TTTCGTCATGACCTAGATGACCTGTCTCTTCGTACTCGGTTATTAAATGGCCTAGCCCAGCAAATGATCAGCCTTGCAAATAATCACAGA
TTAGCTGTAATTTTAACCAATCAGATGACAACAAAGATTGATAGAAATCAGGCCTTGCTTGTTCCTGCATTAGGGGAAAGTTGGGGACAT
GCTGCTACAATACGGCTAATCTTTCATTGGGACCGAAAGCAAAGGTTGGCAACATTGTACAAGTCACCCAGCCAGAAGGAATGCACAGTA
CTGTTTCAAATCAAAGTCAGTATTATTTGATTAGAGTGGGATTTTGATATTGATGGGCGGTAATTATCTAAAGAGAGAATTTACAACTTG
CTTCTGTCAACTTCTGTAGGCAGCAAGCATATTTGAGGACAGCTTTTGATGCTTAGAACATTGTCCCCAAAATAGTAGTATATACAGAAT

>In-frame_ENST00000358181_ENST00000583539_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(amino acids)=419AA_start in transcript=210_stop in transcript=1469
MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSES
GGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKR
RSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMT

--------------------------------------------------------------
>In-frame_ENST00000358181_ENST00000337432_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(transcript)=1680nt_BP=1134nt
ATCTTTGTTTGGGTCTCCCATACTGCGTATAGATGAATGGGTCAGGATATCTGGAACAAAATATGGAGGTGAAGGGTGAGATCGGGAAAC
AAAGGGTATGGCCCCCTAGTTCCCAAAGGGAGCAGGGAGATGGGAATAGAATTGAAGGTAGGTTTTAGGCTACTTGGGAGGAGGAATATT
TAGGTAATTGTGGAGACTTTCTCCTGTGTGATGAAGGCGGCAGACACTGTGATCCTGTGGGCAAGAAGTAAAAATGACCAGCTGAGGATT
TCTTTTCCTCCAGGACTGTGTTGGGGTGACAGGATGCCTGATAAGGATGACATTCGGCTGCTGCCGTCAGCATTGGGTGTGAAGAAGAGA
AAACGAGGACCCAAGAAGCAGAAGGAGAACAAGCCAGGAAAACCCCGAAAACGCAAGAAGCGTGACAGTGAGGAGGAATTTGGTTCTGAG
CGAGATGAGTACCGGGAGAAGTCAGAGAGTGGGGGCAGTGAATATGGAACCGGACCGGGTCGGAAACGAAGAAGGAAGCACCGAGAAAAA
AAGGAGAAGAAGACAAAGCGGCGGAAAAAGGGGGAGGGAGATGGGGGGCAAAAGCAAGTGGAACAGAAGTCATCAGCAACTCTGCTTCTG
ACCTGGGGCCTGGAGGATGTGGAGCATGTGTTCTCTGAGGAGGATTACCACACGCTCACCAACTACAAAGCCTTCAGCCAGTTCATGAGG
CCCCTAATTGCTAAGAAGAATCCTAAGATCCCAATGTCTAAGATGATGACCATCCTTGGGGCCAAATGGAGAGAGTTCAGTGCCAACAAC
CCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGCGGCAGCGGCAGCAGCAGCAGCAGCTGTAGCTGAGCAGGTGTCAGCTGCTGTCTCGTCG
GCCACCCCCATAGCACCCTCCGGACCCCCCGCCCTTCCACCACCCCCTGCTGCTGATATCCAGCCCCCACCCATCCGAAGAGCCAAAACC
AAAGAGGGCAAAGGTCCAGGCCATAAGAGGCGGAGTAAGAGCCCCCGAGTGCCTGATGGACGCAAGAAGCTTCGGGGAAAGAAAATGGCA
CCACTCAAAATAAAACTAGGGCTTCTGGGTGGCAAGAGGAAGAAAGGAGGCTCGGTTCGACTAGTGATAGTGGATGGTATTGCTTTTCCA
TTTCGTCATGACCTAGATGACCTGTCTCTTCGTACTCGGTTATTAAATGGCCTAGCCCAGCAAATGATCAGCCTTGCAAATAATCACAGA
TTAGCTGTAATTTTAACCAATCAGATGACAACAAAGATTGATAGAAATCAGGCCTTGCTTGTTCCTGCATTAGGGGAAAGTTGGGGACAT
GCTGCTACAATACGGCTAATCTTTCATTGGGACCGAAAGCAAAGGTTGGCAACATTGTACAAGTCACCCAGCCAGAAGGAATGCACAGTA
CTGTTTCAAATCAAACCTCAGGGATTTAGAGATACTGTTGTTACTTCTGCATGTTCATTGCAAACAGAAGGTTCCTTGAGCACCCGGAAA
CGGTCACGAGACCCAGAGGAAGAATTATAACCCAGAAACAAATCTCAAAGTGTACAAATTTATTGATGTTGTGAAATCAATGTGTACAAG

>In-frame_ENST00000358181_ENST00000337432_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(amino acids)=449AA_start in transcript=210_stop in transcript=1559
MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSES
GGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKR
RSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMT

--------------------------------------------------------------
>In-frame_ENST00000330494_ENST00000583539_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(transcript)=1617nt_BP=1074nt
ATATGGAGGTGAAGGGTGAGATCGGGAAACAAAGGGTATGGCCCCCTAGTTCCCAAAGGGAGCAGGGAGATGGGAATAGAATTGAAGGTA
GGTTTTAGGCTACTTGGGAGGAGGAATATTTAGGTAATTGTGGAGACTTTCTCCTGTGTGATGAAGGCGGCAGACACTGTGATCCTGTGG
GCAAGAAGTAAAAATGACCAGCTGAGGATTTCTTTTCCTCCAGGACTGTGTTGGGGTGACAGGATGCCTGATAAGGATGACATTCGGCTG
CTGCCGTCAGCATTGGGTGTGAAGAAGAGAAAACGAGGACCCAAGAAGCAGAAGGAGAACAAGCCAGGAAAACCCCGAAAACGCAAGAAG
CGTGACAGTGAGGAGGAATTTGGTTCTGAGCGAGATGAGTACCGGGAGAAGTCAGAGAGTGGGGGCAGTGAATATGGAACCGGACCGGGT
CGGAAACGAAGAAGGAAGCACCGAGAAAAAAAGGAGAAGAAGACAAAGCGGCGGAAAAAGGGGGAGGGAGATGGGGGGCAAAAGCAAGTG
GAACAGAAGTCATCAGCAACTCTGCTTCTGACCTGGGGCCTGGAGGATGTGGAGCATGTGTTCTCTGAGGAGGATTACCACACGCTCACC
AACTACAAAGCCTTCAGCCAGTTCATGAGGCCCCTAATTGCTAAGAAGAATCCTAAGATCCCAATGTCTAAGATGATGACCATCCTTGGG
GCCAAATGGAGAGAGTTCAGTGCCAACAACCCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGCGGCAGCGGCAGCAGCAGCAGCAGCTGTA
GCTGAGCAGGTGTCAGCTGCTGTCTCGTCGGCCACCCCCATAGCACCCTCCGGACCCCCCGCCCTTCCACCACCCCCTGCTGCTGATATC
CAGCCCCCACCCATCCGAAGAGCCAAAACCAAAGAGGGCAAAGGTCCAGGCCATAAGAGGCGGAGTAAGAGCCCCCGAGTGCCTGATGGA
CGCAAGAAGCTTCGGGGAAAGAAAATGGCACCACTCAAAATAAAACTAGGGCTTCTGGGTGGCAAGAGGAAGAAAGGAGGCTCGGTTCGA
CTAGTGATAGTGGATGGTATTGCTTTTCCATTTCGTCATGACCTAGATGACCTGTCTCTTCGTACTCGGTTATTAAATGGCCTAGCCCAG
CAAATGATCAGCCTTGCAAATAATCACAGATTAGCTGTAATTTTAACCAATCAGATGACAACAAAGATTGATAGAAATCAGGCCTTGCTT
GTTCCTGCATTAGGGGAAAGTTGGGGACATGCTGCTACAATACGGCTAATCTTTCATTGGGACCGAAAGCAAAGGTTGGCAACATTGTAC
AAGTCACCCAGCCAGAAGGAATGCACAGTACTGTTTCAAATCAAAGTCAGTATTATTTGATTAGAGTGGGATTTTGATATTGATGGGCGG
TAATTATCTAAAGAGAGAATTTACAACTTGCTTCTGTCAACTTCTGTAGGCAGCAAGCATATTTGAGGACAGCTTTTGATGCTTAGAACA

>In-frame_ENST00000330494_ENST00000583539_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(amino acids)=419AA_start in transcript=150_stop in transcript=1409
MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSES
GGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKR
RSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMT

--------------------------------------------------------------
>In-frame_ENST00000330494_ENST00000337432_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(transcript)=1620nt_BP=1074nt
ATATGGAGGTGAAGGGTGAGATCGGGAAACAAAGGGTATGGCCCCCTAGTTCCCAAAGGGAGCAGGGAGATGGGAATAGAATTGAAGGTA
GGTTTTAGGCTACTTGGGAGGAGGAATATTTAGGTAATTGTGGAGACTTTCTCCTGTGTGATGAAGGCGGCAGACACTGTGATCCTGTGG
GCAAGAAGTAAAAATGACCAGCTGAGGATTTCTTTTCCTCCAGGACTGTGTTGGGGTGACAGGATGCCTGATAAGGATGACATTCGGCTG
CTGCCGTCAGCATTGGGTGTGAAGAAGAGAAAACGAGGACCCAAGAAGCAGAAGGAGAACAAGCCAGGAAAACCCCGAAAACGCAAGAAG
CGTGACAGTGAGGAGGAATTTGGTTCTGAGCGAGATGAGTACCGGGAGAAGTCAGAGAGTGGGGGCAGTGAATATGGAACCGGACCGGGT
CGGAAACGAAGAAGGAAGCACCGAGAAAAAAAGGAGAAGAAGACAAAGCGGCGGAAAAAGGGGGAGGGAGATGGGGGGCAAAAGCAAGTG
GAACAGAAGTCATCAGCAACTCTGCTTCTGACCTGGGGCCTGGAGGATGTGGAGCATGTGTTCTCTGAGGAGGATTACCACACGCTCACC
AACTACAAAGCCTTCAGCCAGTTCATGAGGCCCCTAATTGCTAAGAAGAATCCTAAGATCCCAATGTCTAAGATGATGACCATCCTTGGG
GCCAAATGGAGAGAGTTCAGTGCCAACAACCCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGCGGCAGCGGCAGCAGCAGCAGCAGCTGTA
GCTGAGCAGGTGTCAGCTGCTGTCTCGTCGGCCACCCCCATAGCACCCTCCGGACCCCCCGCCCTTCCACCACCCCCTGCTGCTGATATC
CAGCCCCCACCCATCCGAAGAGCCAAAACCAAAGAGGGCAAAGGTCCAGGCCATAAGAGGCGGAGTAAGAGCCCCCGAGTGCCTGATGGA
CGCAAGAAGCTTCGGGGAAAGAAAATGGCACCACTCAAAATAAAACTAGGGCTTCTGGGTGGCAAGAGGAAGAAAGGAGGCTCGGTTCGA
CTAGTGATAGTGGATGGTATTGCTTTTCCATTTCGTCATGACCTAGATGACCTGTCTCTTCGTACTCGGTTATTAAATGGCCTAGCCCAG
CAAATGATCAGCCTTGCAAATAATCACAGATTAGCTGTAATTTTAACCAATCAGATGACAACAAAGATTGATAGAAATCAGGCCTTGCTT
GTTCCTGCATTAGGGGAAAGTTGGGGACATGCTGCTACAATACGGCTAATCTTTCATTGGGACCGAAAGCAAAGGTTGGCAACATTGTAC
AAGTCACCCAGCCAGAAGGAATGCACAGTACTGTTTCAAATCAAACCTCAGGGATTTAGAGATACTGTTGTTACTTCTGCATGTTCATTG
CAAACAGAAGGTTCCTTGAGCACCCGGAAACGGTCACGAGACCCAGAGGAAGAATTATAACCCAGAAACAAATCTCAAAGTGTACAAATT
TATTGATGTTGTGAAATCAATGTGTACAAGTGGACTTGTTACCTTAAAGTATAAATAAACACACTATGGCATGAATGAATCCAGATCATA

>In-frame_ENST00000330494_ENST00000337432_TCGA-OR-A5KY_CHD3_chr17_7797253_+_RAD51C_chr17_56787219_length(amino acids)=449AA_start in transcript=150_stop in transcript=1499
MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSES
GGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKR
RSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKGGSVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CHD3-RAD51C


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneRAD51Cchr17:7797253chr17:56787219ENST000004217820279_1360136.0RAD51B%2C RAD51D and XRCC3
TgeneRAD51Cchr17:7797253chr17:56787220ENST000004217820279_1360136.0RAD51B%2C RAD51D and XRCC3


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneRAD51Cchr17:7797253chr17:56787219ENST000003374323979_136235.0377.0RAD51B%2C RAD51D and XRCC3
TgeneRAD51Cchr17:7797253chr17:56787220ENST000003374323979_136235.0377.0RAD51B%2C RAD51D and XRCC3


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CHD3-RAD51C


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CHD3-RAD51C


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCHD3C4748701SNIJDERS BLOK-CAMPEAU SYNDROME2GENOMICS_ENGLAND;UNIPROT
HgeneCHD3C0033578Prostatic Neoplasms1CTD_human
HgeneCHD3C0036920Sezary Syndrome1CTD_human
HgeneCHD3C0221355Macrocephaly1GENOMICS_ENGLAND
HgeneCHD3C0376358Malignant neoplasm of prostate1CTD_human
HgeneCHD3C0557874Global developmental delay1GENOMICS_ENGLAND
HgeneCHD3C2931456Prostate cancer, familial1CTD_human
HgeneCHD3C3714756Intellectual Disability1GENOMICS_ENGLAND
HgeneCHD3C4722327PROSTATE CANCER, HEREDITARY, 11CTD_human
TgeneRAD51CC0346153Breast Cancer, Familial7CLINGEN
TgeneRAD51CC3150653FANCONI ANEMIA, COMPLEMENTATION GROUP O6CLINGEN;CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneRAD51CC3150659BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 35CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneRAD51CC0015625Fanconi Anemia4CTD_human;GENOMICS_ENGLAND
TgeneRAD51CC0006142Malignant neoplasm of breast2CTD_human
TgeneRAD51CC0677776Hereditary Breast and Ovarian Cancer Syndrome2ORPHANET
TgeneRAD51CC0678222Breast Carcinoma2CTD_human
TgeneRAD51CC1257931Mammary Neoplasms, Human2CTD_human
TgeneRAD51CC1458155Mammary Neoplasms2CTD_human
TgeneRAD51CC4704874Mammary Carcinoma, Human2CTD_human
TgeneRAD51CC0023465Acute monocytic leukemia1GENOMICS_ENGLAND
TgeneRAD51CC0023467Leukemia, Myelocytic, Acute1GENOMICS_ENGLAND
TgeneRAD51CC0030312Pancytopenia1GENOMICS_ENGLAND
TgeneRAD51CC0265219Miller Dieker syndrome1GENOMICS_ENGLAND
TgeneRAD51CC0919267ovarian neoplasm1CTD_human
TgeneRAD51CC1140680Malignant neoplasm of ovary1CTD_human;GENOMICS_ENGLAND
TgeneRAD51CC1855710Bone marrow hypocellularity1GENOMICS_ENGLAND
TgeneRAD51CC3463824MYELODYSPLASTIC SYNDROME1GENOMICS_ENGLAND
TgeneRAD51CC4228778Abnormality of radial ray1GENOMICS_ENGLAND