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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CIRBP-PKNOX1 (FusionGDB2 ID:16861)

Fusion Gene Summary for CIRBP-PKNOX1

check button Fusion gene summary
Fusion gene informationFusion gene name: CIRBP-PKNOX1
Fusion gene ID: 16861
HgeneTgene
Gene symbol

CIRBP

PKNOX1

Gene ID

1153

5316

Gene namecold inducible RNA binding proteinPBX/knotted 1 homeobox 1
SynonymsCIRPPREP1|pkonx1c
Cytomap

19p13.3

21q22.3

Type of geneprotein-codingprotein-coding
Descriptioncold-inducible RNA-binding proteinA18 hnRNPglycine-rich RNA binding proteintesticular tissue protein Li 39homeobox protein PKNOX1PBX/knotted homeobox 1Pbx regulating protein-1homeobox protein PREP-1human homeobox-containing protein
Modification date2020032720200313
UniProtAcc

Q14011

.
Ensembl transtripts involved in fusion geneENST00000588030, ENST00000589660, 
ENST00000588090, ENST00000591935, 
ENST00000589710, ENST00000588230, 
ENST00000413636, ENST00000586472, 
ENST00000589686, ENST00000444172, 
ENST00000587323, ENST00000320936, 
ENST00000587896, ENST00000589235, 
ENST00000585630, ENST00000586773, 
ENST00000590188, 		ENST00000291547, 
ENST00000432907, ENST00000607150, 
Fusion gene scores* DoF score12 X 7 X 6=50413 X 10 X 6=780
# samples 1315
** MAII scorelog2(13/504*10)=-1.95491211047146
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/780*10)=-2.37851162325373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CIRBP [Title/Abstract] AND PKNOX1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCIRBP(1271411)-PKNOX1(44450156), # samples:1
Anticipated loss of major functional domain due to fusion event.CIRBP-PKNOX1 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
CIRBP-PKNOX1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCIRBP

GO:0009411

response to UV

11574538

HgeneCIRBP

GO:0045727

positive regulation of translation

11574538

HgeneCIRBP

GO:0048255

mRNA stabilization

11574538


check buttonFusion gene breakpoints across CIRBP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PKNOX1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ADA500684CIRBPchr19

1271411

+PKNOX1chr21

44450156

+


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Fusion Gene ORF analysis for CIRBP-PKNOX1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000588030ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000588030ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000588030ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000589660ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000589660ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000589660ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000588090ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000588090ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000588090ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000591935ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000591935ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000591935ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000589710ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000589710ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000589710ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000588230ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000588230ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000588230ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
intron-3CDSENST00000413636ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
intron-3CDSENST00000413636ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
intron-intronENST00000413636ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000586472ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000586472ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000586472ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000589686ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000589686ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000589686ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000444172ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000444172ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000444172ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000587323ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000587323ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000587323ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000320936ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000320936ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000320936ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000587896ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000587896ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000587896ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000589235ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000589235ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000589235ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000585630ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000585630ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000585630ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
Frame-shiftENST00000586773ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
In-frameENST00000586773ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
5CDS-intronENST00000586773ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
intron-3CDSENST00000590188ENST00000291547CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
intron-3CDSENST00000590188ENST00000432907CIRBPchr19

1271411

+PKNOX1chr21

44450156

+
intron-intronENST00000590188ENST00000607150CIRBPchr19

1271411

+PKNOX1chr21

44450156

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000588030CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+81052526601191
ENST00000589660CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+60532055396113
ENST00000588090CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+761476118552144
ENST00000591935CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+62033546411121
ENST00000589710CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+697412132488118
ENST00000588230CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+63535064426120
ENST00000586472CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+63535064426120
ENST00000589686CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+696411131487118
ENST00000444172CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+52524012531663
ENST00000587323CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+63034559421120
ENST00000320936CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+63034559421120
ENST00000587896CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+62133611412133
ENST00000589235CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+61733246408120
ENST00000585630CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+61833353409118
ENST00000586773CIRBPchr191271411+ENST00000432907PKNOX1chr2144450156+59931434390118

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000588030ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.466278370.5337217
ENST00000589660ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.30260480.6973952
ENST00000588090ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.523684140.47631583
ENST00000591935ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.52329480.4767052
ENST00000589710ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.461310950.538689
ENST00000588230ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.45406770.5459323
ENST00000586472ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.45406770.5459323
ENST00000589686ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.439791230.5602088
ENST00000444172ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.8824740.11752604
ENST00000587323ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.453058840.54694116
ENST00000320936ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.453058840.54694116
ENST00000587896ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.47699310.5230069
ENST00000589235ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.438949530.5610505
ENST00000585630ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.36422560.6357744
ENST00000586773ENST00000432907CIRBPchr191271411+PKNOX1chr2144450156+0.365071060.63492894

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Fusion Genomic Features for CIRBP-PKNOX1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CIRBP-PKNOX1


check button Go to

FGviewer for the breakpoints of chr19:1271411-chr21:44450156

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CIRBP

Q14011

.
FUNCTION: Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed. {ECO:0000250, ECO:0000269|PubMed:11574538, ECO:0000269|PubMed:16513844}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePKNOX1chr19:1271411chr21:44450156ENST00000291547011259_3210437.0DNA bindingHomeobox%3B TALE-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCIRBPchr19:1271411chr21:44450156ENST00000320936+1792_1580173.0Compositional biasNote=Gly-rich
HgeneCIRBPchr19:1271411chr21:44450156ENST00000585630+1692_1580173.0Compositional biasNote=Gly-rich
HgeneCIRBPchr19:1271411chr21:44450156ENST00000586472+1892_1580173.0Compositional biasNote=Gly-rich
HgeneCIRBPchr19:1271411chr21:44450156ENST00000588030+1792_1580173.0Compositional biasNote=Gly-rich
HgeneCIRBPchr19:1271411chr21:44450156ENST00000588090+1792_1580173.0Compositional biasNote=Gly-rich
HgeneCIRBPchr19:1271411chr21:44450156ENST00000589660+1792_1580173.0Compositional biasNote=Gly-rich
HgeneCIRBPchr19:1271411chr21:44450156ENST00000320936+176_840173.0DomainRRM
HgeneCIRBPchr19:1271411chr21:44450156ENST00000585630+166_840173.0DomainRRM
HgeneCIRBPchr19:1271411chr21:44450156ENST00000586472+186_840173.0DomainRRM
HgeneCIRBPchr19:1271411chr21:44450156ENST00000588030+176_840173.0DomainRRM
HgeneCIRBPchr19:1271411chr21:44450156ENST00000588090+176_840173.0DomainRRM
HgeneCIRBPchr19:1271411chr21:44450156ENST00000589660+176_840173.0DomainRRM


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Fusion Gene Sequence for CIRBP-PKNOX1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000588030_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=810nt_BP=525nt
AGTCCCTTAGGGTGTGGGGCGAGGGCCTGCCTGCCTGCTTCGTGGCCTGGGCAGGACCCTGGCCCCCTCAGGACCTGCCAGTATGGGGGA
GACGCGACCACCAGCTCTCCCCAGCCACAGGAGTCGGGGACTCCCACTCTGCCACACCCACCTGCTCCCCTTCCTGGAGTCTCACATCTG
TGTGGCTTGCTGCAGGGAGATCACCAGGCCGACTGGGAGGACCTAGGACTCCGCAGGGTACCTTGGGCTGGCAGGCCGCCATGGCATCAG
ATGAAGGCAAACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTG
AAGTGGTGGTTGTGAAAGACAGGGAGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCA
TGATGGCCATGAATGGGAAGGGGGGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACAT
CAGCGGGCTGGTCTTGGAGAACAGTGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTT
TACACAGTTTTATTTCTAATATGTTTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCG
GTGCAGCGACTTCTTTCAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGTGTGTGCGTGTGTGTGGATTTTTAAAGAAATTCTTT

>In-frame_ENST00000588030_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=191AA_start in transcript=26_stop in transcript=601
MPACFVAWAGPWPPQDLPVWGRRDHQLSPATGVGDSHSATPTCSPSWSLTSVWLAAGRSPGRLGGPRTPQGTLGWQAAMASDEGKLFVGG
LSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGRGRGFSRGPLPTSAGWSWRTV

--------------------------------------------------------------
>In-frame_ENST00000589660_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=605nt_BP=320nt
CGACGCCCCGCAGGGGAGGAGGCCCGGGAGGAGTATCAGGGTGCAGGAGGCCGCCATGGCATCAGATGAAGGCAAACTTTTTGTTGGAGG
GCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGGTTGTGAAAGACAGGGA
GACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCATGATGGCCATGAATGGGAAGGGGGG
CCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACATCAGCGGGCTGGTCTTGGAGAACAGT
GACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTTTACACAGTTTTATTTCTAATATGTT
TTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCGGTGCAGCGACTTCTTTCAAGTGTGT

>In-frame_ENST00000589660_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=113AA_start in transcript=55_stop in transcript=396
MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGRGRGFSRGP

--------------------------------------------------------------
>In-frame_ENST00000588090_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=761nt_BP=476nt
AAACGCCGCGGACGGAGCGAGGCCGCAGCGCCCCCTGGTGTCCGCAACGGGCAGCGCGTCCCGGTCGGGTCCCGCATGGTCAGTGGCCAG
CAGGGGTGGATGAAGGGGTCCCAGCCGCCTGAGACCCCCGGTGGGGACACAGGATCGCGGTGAGATACCTGGGAGTCACGGGTGCTCGCA
GACGCAGCTGACCCCAGAGGCACAGGCCGCCATGGCATCAGATGAAGGCAAACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCA
GTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGGTTGTGAAAGACAGGGAGACCCAGAGATCTCGGGGATTTGG
GTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCATGATGGCCATGAATGGGAAGGGGGGCCGGGGCTTCTTCCGTGGGGGCCG
AGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACATCAGCGGGCTGGTCTTGGAGAACAGTGACTCCCTGCAGTAGGGGCAGGAG
CAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTTTACACAGTTTTATTTCTAATATGTTTTATATGTAGATATAGAAGAGTGC
ACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCGGTGCAGCGACTTCTTTCAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT

>In-frame_ENST00000588090_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=144AA_start in transcript=118_stop in transcript=552
MRPPVGTQDRGEIPGSHGCSQTQLTPEAQAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDD

--------------------------------------------------------------
>In-frame_ENST00000591935_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=620nt_BP=335nt
GGATCGCGGTGAGATACCTGGGAGTCACGGGTGCTCGCAGACGCAGCTGACCCCAGAGGCACAGGCCGCCATGGCATCAGATGAAGGCAA
ACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGGT
TGTGAAAGACAGGGAGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCATGATGGCCAT
GAATGGGAAGGGGGGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACATCAGCGGGCTG
GTCTTGGAGAACAGTGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTTTACACAGTTT
TATTTCTAATATGTTTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCGGTGCAGCGAC

>In-frame_ENST00000591935_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=121AA_start in transcript=46_stop in transcript=411
MTPEAQAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGR

--------------------------------------------------------------
>In-frame_ENST00000589710_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=697nt_BP=412nt
CCTCACTCGCGCGTTAGGAGGCTCGGGTCGTTGTGGTGCGCTGTCTTCCCGCTTGCGTCAGGGACCTGCCCGACTCAGTGGAAGCGGGGA
GAGGTGGTGAGAGATGACCCCTGTTGAGGATTTCATTGGTGTCTGCCACAGGCCGCCATGGCATCAGATGAAGGCAAACTTTTTGTTGGA
GGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGGTTGTGAAAGACAGG
GAGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCATGATGGCCATGAATGGGAAGGGG
GGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACATCAGCGGGCTGGTCTTGGAGAACA
GTGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTTTACACAGTTTTATTTCTAATATG
TTTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCGGTGCAGCGACTTCTTTCAAGTGT

>In-frame_ENST00000589710_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=118AA_start in transcript=132_stop in transcript=488
MPQAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGRGRG

--------------------------------------------------------------
>In-frame_ENST00000588230_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=635nt_BP=350nt
CTCACTCGCGCGTTAGGAGGCTCGGGTCGTTGTGGTGCGCTGTCTTCCCGCTTGCGTCAGGGACCTGCCCGACTCAGTGGCCGCCATGGC
ATCAGATGAAGGCAAACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGAT
CTCTGAAGTGGTGGTTGTGAAAGACAGGGAGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGA
TGCCATGATGGCCATGAATGGGAAGGGGGGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCC
CACATCAGCGGGCTGGTCTTGGAGAACAGTGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAA
CATTTTACACAGTTTTATTTCTAATATGTTTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTT
TGCCGGTGCAGCGACTTCTTTCAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGTGTGTGCGTGTGTGTGGATTTTTAAAGAAAT

>In-frame_ENST00000588230_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=120AA_start in transcript=64_stop in transcript=426
MPDSVAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGRG

--------------------------------------------------------------
>In-frame_ENST00000586472_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=635nt_BP=350nt
CTCACTCGCGCGTTAGGAGGCTCGGGTCGTTGTGGTGCGCTGTCTTCCCGCTTGCGTCAGGGACCTGCCCGACTCAGTGGCCGCCATGGC
ATCAGATGAAGGCAAACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGAT
CTCTGAAGTGGTGGTTGTGAAAGACAGGGAGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGA
TGCCATGATGGCCATGAATGGGAAGGGGGGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCC
CACATCAGCGGGCTGGTCTTGGAGAACAGTGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAA
CATTTTACACAGTTTTATTTCTAATATGTTTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTT
TGCCGGTGCAGCGACTTCTTTCAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGTGTGTGCGTGTGTGTGGATTTTTAAAGAAAT

>In-frame_ENST00000586472_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=120AA_start in transcript=64_stop in transcript=426
MPDSVAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGRG

--------------------------------------------------------------
>In-frame_ENST00000589686_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=696nt_BP=411nt
CTCACTCGCGCGTTAGGAGGCTCGGGTCGTTGTGGTGCGCTGTCTTCCCGCTTGCGTCAGGGACCTGCCCGACTCAGTGGAAGCGGGGAG
AGGTGGTGAGAGATGACCCCTGTTGAGGATTTCATTGGTGTCTGCCACAGGCCGCCATGGCATCAGATGAAGGCAAACTTTTTGTTGGAG
GGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGGTTGTGAAAGACAGGG
AGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCATGATGGCCATGAATGGGAAGGGGG
GCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACATCAGCGGGCTGGTCTTGGAGAACAG
TGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTTTACACAGTTTTATTTCTAATATGT
TTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCGGTGCAGCGACTTCTTTCAAGTGTG

>In-frame_ENST00000589686_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=118AA_start in transcript=131_stop in transcript=487
MPQAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGRGRG

--------------------------------------------------------------
>In-frame_ENST00000444172_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=525nt_BP=240nt
ACTCGCGCGTTAGGAGGCTCGGGTCGTTGTGGTGCGCTGTCTTCCCGCTTGCGTCAGGGACCTGCCCGACTCAGTGGCCGCCATGGCATC
AGATGAAGGCAAACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTC
TGAAGGGGGGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACATCAGCGGGCTGGTCTT
GGAGAACAGTGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTTTACACAGTTTTATTT
CTAATATGTTTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCGGTGCAGCGACTTCTT

>In-frame_ENST00000444172_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=63AA_start in transcript=125_stop in transcript=316

--------------------------------------------------------------
>In-frame_ENST00000587323_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=630nt_BP=345nt
TCGCGCGTTAGGAGGCTCGGGTCGTTGTGGTGCGCTGTCTTCCCGCTTGCGTCAGGGACCTGCCCGACTCAGTGGCCGCCATGGCATCAG
ATGAAGGCAAACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTG
AAGTGGTGGTTGTGAAAGACAGGGAGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCA
TGATGGCCATGAATGGGAAGGGGGGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACAT
CAGCGGGCTGGTCTTGGAGAACAGTGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTT
TACACAGTTTTATTTCTAATATGTTTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCG
GTGCAGCGACTTCTTTCAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGTGTGTGCGTGTGTGTGGATTTTTAAAGAAATTCTTT

>In-frame_ENST00000587323_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=120AA_start in transcript=59_stop in transcript=421
MPDSVAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGRG

--------------------------------------------------------------
>In-frame_ENST00000320936_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=630nt_BP=345nt
TCGCGCGTTAGGAGGCTCGGGTCGTTGTGGTGCGCTGTCTTCCCGCTTGCGTCAGGGACCTGCCCGACTCAGTGGCCGCCATGGCATCAG
ATGAAGGCAAACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTG
AAGTGGTGGTTGTGAAAGACAGGGAGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCA
TGATGGCCATGAATGGGAAGGGGGGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACAT
CAGCGGGCTGGTCTTGGAGAACAGTGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTT
TACACAGTTTTATTTCTAATATGTTTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCG
GTGCAGCGACTTCTTTCAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGTGTGTGCGTGTGTGTGGATTTTTAAAGAAATTCTTT

>In-frame_ENST00000320936_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=120AA_start in transcript=59_stop in transcript=421
MPDSVAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGRG

--------------------------------------------------------------
>In-frame_ENST00000587896_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=621nt_BP=336nt
GGCTCGGGTCGTTGTGGTGCGCTGTCTTCCCGCTTGCGTCAGGGACCTGCCCGACTCAGTGTGTGGCCGCCATGGCATCAGATGAAGGCA
AACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGG
TTGTGAAAGACAGGGAGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCATGATGGCCA
TGAATGGGAAGGGGGGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACATCAGCGGGCT
GGTCTTGGAGAACAGTGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTTTACACAGTT
TTATTTCTAATATGTTTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCGGTGCAGCGA

>In-frame_ENST00000587896_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=133AA_start in transcript=11_stop in transcript=412
MWCAVFPLASGTCPTQCVAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGK

--------------------------------------------------------------
>In-frame_ENST00000589235_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=617nt_BP=332nt
GGCTCGGGTCGTTGTGGTGCGCTGTCTTCCCGCTTGCGTCAGGGACCTGCCCGACTCAGTGGCCGCCATGGCATCAGATGAAGGCAAACT
TTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGGTTGT
GAAAGACAGGGAGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCATGATGGCCATGAA
TGGGAAGGGGGGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACATCAGCGGGCTGGTC
TTGGAGAACAGTGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTTTACACAGTTTTAT
TTCTAATATGTTTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCGGTGCAGCGACTTC

>In-frame_ENST00000589235_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=120AA_start in transcript=46_stop in transcript=408
MPDSVAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGRG

--------------------------------------------------------------
>In-frame_ENST00000585630_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=618nt_BP=333nt
GGAAGCGGGGAGAGGTGGTGAGAGATGACCCCTGTTGAGGATTTCATTGGTGTCTGCCACAGGCCGCCATGGCATCAGATGAAGGCAAAC
TTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGGTTG
TGAAAGACAGGGAGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCATGATGGCCATGA
ATGGGAAGGGGGGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACATCAGCGGGCTGGT
CTTGGAGAACAGTGACTCCCTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTTTACACAGTTTTA
TTTCTAATATGTTTTATATGTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCGGTGCAGCGACTT

>In-frame_ENST00000585630_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=118AA_start in transcript=53_stop in transcript=409
MPQAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGRGRG

--------------------------------------------------------------
>In-frame_ENST00000586773_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(transcript)=599nt_BP=314nt
GAGAGATGACCCCTGTTGAGGATTTCATTGGTGTCTGCCACAGGCCGCCATGGCATCAGATGAAGGCAAACTTTTTGTTGGAGGGCTGAG
TTTTGACACCAATGAGCAGTCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGGTTGTGAAAGACAGGGAGACCCA
GAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCATGATGGCCATGAATGGGAAGGGGGGCCGGGG
CTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGGCCCCTGCCCACATCAGCGGGCTGGTCTTGGAGAACAGTGACTCC
CTGCAGTAGGGGCAGGAGCAGACGCACCTGACTTTTTGGAGTTTGCACAGCAAACATTTTACACAGTTTTATTTCTAATATGTTTTATAT
GTAGATATAGAAGAGTGCACTTTTGTATTTCATAGTAAGCTTAAAGCGCGTCTTTGCCGGTGCAGCGACTTCTTTCAAGTGTGTGTGTGT

>In-frame_ENST00000586773_ENST00000432907_DA500684_CIRBP_chr19_1271411_+_PKNOX1_chr21_44450156_length(amino acids)=118AA_start in transcript=34_stop in transcript=390
MPQAAMASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKGGRGFFRGGRGRGRG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CIRBP-PKNOX1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CIRBP-PKNOX1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CIRBP-PKNOX1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCIRBPC0151744Myocardial Ischemia1CTD_human
HgeneCIRBPC0600467Neurogenic Inflammation1CTD_human
HgeneCIRBPC0751865Alcohol-Induced Disorders, Nervous System1CTD_human
HgeneCIRBPC1510586Autism Spectrum Disorders1CTD_human