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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CLPTM1-AP1M1 (FusionGDB2 ID:17322)

Fusion Gene Summary for CLPTM1-AP1M1

check button Fusion gene summary
Fusion gene informationFusion gene name: CLPTM1-AP1M1
Fusion gene ID: 17322
HgeneTgene
Gene symbol

CLPTM1

AP1M1

Gene ID

1209

8907

Gene nameCLPTM1 regulator of GABA type A receptor forward traffickingadaptor related protein complex 1 subunit mu 1
Synonyms-AP47|CLAPM2|CLTNM|MU-1A
Cytomap

19q13.32

19p13.11

Type of geneprotein-codingprotein-coding
Descriptioncleft lip and palate transmembrane protein 1CLPTM1, transmembrane proteincleft lip and palate associated transmembrane protein 1AP-1 complex subunit mu-1AP-mu chain family member mu1AHA1 47 kDa subunitadapter-related protein complex 1 subunit mu-1adaptor protein complex AP-1 mu-1 subunitadaptor protein complex AP-1 subunit mu-1adaptor related protein complex 1 mu 1 subunitc
Modification date2020031320200313
UniProtAcc.

Q9BXS5

Ensembl transtripts involved in fusion geneENST00000546079, ENST00000541297, 
ENST00000337392, ENST00000589158, 
ENST00000291439, ENST00000541844, 
ENST00000590756, ENST00000429941, 
ENST00000444449, 
Fusion gene scores* DoF score16 X 12 X 8=15365 X 5 X 4=100
# samples 206
** MAII scorelog2(20/1536*10)=-2.94110631094643
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/100*10)=-0.736965594166206
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CLPTM1 [Title/Abstract] AND AP1M1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCLPTM1(45458724)-AP1M1(16337231), # samples:1
CLPTM1(45458724)-AP1M1(16337232), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CLPTM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across AP1M1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-55-6972CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
ChimerDB4LUADTCGA-55-6972-01ACLPTM1chr19

45458724

-AP1M1chr19

16337232

+


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Fusion Gene ORF analysis for CLPTM1-AP1M1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000546079ENST00000291439CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000546079ENST00000541844CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000546079ENST00000590756CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000546079ENST00000429941CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000546079ENST00000444449CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000541297ENST00000291439CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000541297ENST00000541844CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000541297ENST00000590756CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000541297ENST00000429941CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000541297ENST00000444449CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
In-frameENST00000337392ENST00000291439CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
In-frameENST00000337392ENST00000541844CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
In-frameENST00000337392ENST00000590756CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
In-frameENST00000337392ENST00000429941CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
In-frameENST00000337392ENST00000444449CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000589158ENST00000291439CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000589158ENST00000541844CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000589158ENST00000590756CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000589158ENST00000429941CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000589158ENST00000444449CLPTM1chr19

45458724

+AP1M1chr19

16337231

+
intron-3CDSENST00000546079ENST00000291439CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000546079ENST00000541844CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000546079ENST00000590756CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000546079ENST00000429941CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000546079ENST00000444449CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000541297ENST00000291439CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000541297ENST00000541844CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000541297ENST00000590756CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000541297ENST00000429941CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000541297ENST00000444449CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
In-frameENST00000337392ENST00000291439CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
In-frameENST00000337392ENST00000541844CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
In-frameENST00000337392ENST00000590756CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
In-frameENST00000337392ENST00000429941CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
In-frameENST00000337392ENST00000444449CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000589158ENST00000291439CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000589158ENST00000541844CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000589158ENST00000590756CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000589158ENST00000429941CLPTM1chr19

45458724

-AP1M1chr19

16337232

+
intron-3CDSENST00000589158ENST00000444449CLPTM1chr19

45458724

-AP1M1chr19

16337232

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000337392CLPTM1chr1945458724+ENST00000291439AP1M1chr1916337231+186222287947286
ENST00000337392CLPTM1chr1945458724+ENST00000541844AP1M1chr1916337231+142422287947286
ENST00000337392CLPTM1chr1945458724+ENST00000590756AP1M1chr1916337231+142422287947286
ENST00000337392CLPTM1chr1945458724+ENST00000429941AP1M1chr1916337231+113822287788233
ENST00000337392CLPTM1chr1945458724+ENST00000444449AP1M1chr1916337231+185822287947286
ENST00000337392CLPTM1chr1945458724-ENST00000291439AP1M1chr1916337232+186222287947286
ENST00000337392CLPTM1chr1945458724-ENST00000541844AP1M1chr1916337232+142422287947286
ENST00000337392CLPTM1chr1945458724-ENST00000590756AP1M1chr1916337232+142422287947286
ENST00000337392CLPTM1chr1945458724-ENST00000429941AP1M1chr1916337232+113822287788233
ENST00000337392CLPTM1chr1945458724-ENST00000444449AP1M1chr1916337232+185822287947286

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000337392ENST00000291439CLPTM1chr1945458724+AP1M1chr1916337231+0.0037013610.9962986
ENST00000337392ENST00000541844CLPTM1chr1945458724+AP1M1chr1916337231+0.0068342970.9931657
ENST00000337392ENST00000590756CLPTM1chr1945458724+AP1M1chr1916337231+0.0068342970.9931657
ENST00000337392ENST00000429941CLPTM1chr1945458724+AP1M1chr1916337231+0.0078791890.99212086
ENST00000337392ENST00000444449CLPTM1chr1945458724+AP1M1chr1916337231+0.0037268320.99627316
ENST00000337392ENST00000291439CLPTM1chr1945458724-AP1M1chr1916337232+0.0037013610.9962986
ENST00000337392ENST00000541844CLPTM1chr1945458724-AP1M1chr1916337232+0.0068342970.9931657
ENST00000337392ENST00000590756CLPTM1chr1945458724-AP1M1chr1916337232+0.0068342970.9931657
ENST00000337392ENST00000429941CLPTM1chr1945458724-AP1M1chr1916337232+0.0078791890.99212086
ENST00000337392ENST00000444449CLPTM1chr1945458724-AP1M1chr1916337232+0.0037268320.99627316

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Fusion Genomic Features for CLPTM1-AP1M1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CLPTM1chr1945458724+AP1M1chr1916337231+2.89E-101
CLPTM1chr1945458724+AP1M1chr1916337231+2.89E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CLPTM1-AP1M1


check button Go to

FGviewer for the breakpoints of chr19:45458724-chr19:16337231

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AP1M1

Q9BXS5

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLPTM1chr19:45458724chr19:16337231ENST00000337392+1142_35424.0670.0Topological domainExtracellular
HgeneCLPTM1chr19:45458724chr19:16337231ENST00000337392+114376_39024.0670.0Topological domainCytoplasmic
HgeneCLPTM1chr19:45458724chr19:16337231ENST00000337392+114412_41624.0670.0Topological domainExtracellular
HgeneCLPTM1chr19:45458724chr19:16337231ENST00000337392+114438_47724.0670.0Topological domainCytoplasmic
HgeneCLPTM1chr19:45458724chr19:16337231ENST00000337392+114499_50224.0670.0Topological domainExtracellular
HgeneCLPTM1chr19:45458724chr19:16337231ENST00000337392+114524_66924.0670.0Topological domainCytoplasmic
HgeneCLPTM1chr19:45458724chr19:16337232ENST00000337392-1142_35424.0670.0Topological domainExtracellular
HgeneCLPTM1chr19:45458724chr19:16337232ENST00000337392-114376_39024.0670.0Topological domainCytoplasmic
HgeneCLPTM1chr19:45458724chr19:16337232ENST00000337392-114412_41624.0670.0Topological domainExtracellular
HgeneCLPTM1chr19:45458724chr19:16337232ENST00000337392-114438_47724.0670.0Topological domainCytoplasmic
HgeneCLPTM1chr19:45458724chr19:16337232ENST00000337392-114499_50224.0670.0Topological domainExtracellular
HgeneCLPTM1chr19:45458724chr19:16337232ENST00000337392-114524_66924.0670.0Topological domainCytoplasmic
HgeneCLPTM1chr19:45458724chr19:16337231ENST00000337392+114355_37524.0670.0TransmembraneHelical
HgeneCLPTM1chr19:45458724chr19:16337231ENST00000337392+114391_41124.0670.0TransmembraneHelical
HgeneCLPTM1chr19:45458724chr19:16337231ENST00000337392+114417_43724.0670.0TransmembraneHelical
HgeneCLPTM1chr19:45458724chr19:16337231ENST00000337392+114478_49824.0670.0TransmembraneHelical
HgeneCLPTM1chr19:45458724chr19:16337231ENST00000337392+114503_52324.0670.0TransmembraneHelical
HgeneCLPTM1chr19:45458724chr19:16337232ENST00000337392-114355_37524.0670.0TransmembraneHelical
HgeneCLPTM1chr19:45458724chr19:16337232ENST00000337392-114391_41124.0670.0TransmembraneHelical
HgeneCLPTM1chr19:45458724chr19:16337232ENST00000337392-114417_43724.0670.0TransmembraneHelical
HgeneCLPTM1chr19:45458724chr19:16337232ENST00000337392-114478_49824.0670.0TransmembraneHelical
HgeneCLPTM1chr19:45458724chr19:16337232ENST00000337392-114503_52324.0670.0TransmembraneHelical
TgeneAP1M1chr19:45458724chr19:16337231ENST00000291439412168_421182.0424.0DomainMHD
TgeneAP1M1chr19:45458724chr19:16337231ENST00000444449513168_421194.0436.0DomainMHD
TgeneAP1M1chr19:45458724chr19:16337232ENST00000291439412168_421182.0424.0DomainMHD
TgeneAP1M1chr19:45458724chr19:16337232ENST00000444449513168_421194.0436.0DomainMHD


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Fusion Gene Sequence for CLPTM1-AP1M1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000337392_ENST00000291439_TCGA-55-6972_CLPTM1_chr19_45458724_+_AP1M1_chr19_16337231_length(transcript)=1862nt_BP=222nt
AAGTGGCCTTCCTGAGAGGCGTGGCTGCGGCACTCTTGCCGGATAGGGTGGCCCGGCGGGGCTAGGAAAGCGTGAAATCTCGCGCGATTG
CGCTGCGAAGTCGGGGACGGGGCGGGGCTGGCGGCGGGGGCGGGGACCCGGAGCGGGAAGATGGCGGCGGCGCAGGAGGCGGACGGGGCC
CGCAGCGCCGTGGTGGCGGCCGGGGGAGGCAGCTCCGGTCAGGTCAGCGCCAACGGCAATGTCCTGCGCAGCGAGATCGTGGGCTCCATC
AAGATGCGAGTCTTCCTCTCGGGCATGCCCGAGCTGCGCCTGGGCCTCAACGACAAGGTCCTCTTTGACAACACGGGCCGCGGCAAAAGC
AAATCCGTGGAGCTGGAGGATGTGAAGTTCCACCAGTGTGTGCGGCTATCACGCTTCGAGAATGACCGCACCATCTCCTTCATCCCACCC
GACGGCGAGTTCGAGCTCATGTCCTACCGTCTCAACACCCACGTCAAGCCTTTGATATGGATCGAGTCGGTGATCGAGAAGCACTCCCAC
AGCCGCATCGAGTACATGATCAAGGCCAAAAGCCAGTTCAAGCGGCGGTCAACAGCCAACAACGTGGAGATCCACATTCCCGTGCCCAAT
GATGCCGACTCACCCAAGTTCAAGACGACGGTGGGGAGCGTTAAGTGGGTCCCCGAGAACAGCGAGATCGTGTGGTCCATCAAGTCCTTC
CCGGGCGGCAAGGAGTACCTGATGCGGGCCCACTTCGGCCTGCCTAGTGTGGAGGCCGAAGACAAGGAGGGCAAGCCCCCGATCAGTGTC
AAGTTCGAGATCCCTTACTTCACTACCTCCGGCATCCAGGTGCGCTACCTGAAGATCATTGAGAAGAGTGGGTACCAGGCCCTGCCCTGG
GTGCGTTATATCACGCAGAATGGAGATTACCAGCTCCGGACCCAGTGAGGGGCTGTCGCAGCCAACACCCCGGCCTCGGGGCTCCTGGTG
GCAGCACCAGGGGACACACCTGCCAAACCCACCAGATGGAGGGGCCCTCCCTGGTCTCTGGCCACCCTCCCAGCCTCTGCCCAGGGACCC
CTGCCTTCCCCAGGCCATCTGCTCTGCCGTCGACACTCGTCTCAGAAGCCCCTTTCCCAGAAGAGGCTGGTCTTCAAGAAGTCTCGTTTC
TTTGCCCCTGAAGTCAGTTTCAGGGGAAGGATGTGAAATTTTTCCGTGTAGAGGTTACAGCCTTTTATGCTGTTGAGCTCCCAGGTACCA
AAAAGCTTGGCCAACGCTTGCCAGCCAGCCAGCTGCAGGTGGCATCTGCCACGAAGGAAGCGCCAGCCTCGCCAGGCCAGCAGGGGCGTC
GTTTTGTTGCCATTTTGTTGAACGTTATGGGTTTATGGGTGTTCCTGGAACTTGTCTTTGTGCATTCGTTGCTGTTTGTGTTACCCTCAC
TGTCCCCATGTCCCACCCACGTCCTACGGCACTCAGGAAGCACTTGGTGAGGACGAGCCCTCACCCTTCTTGTCTTCCTTCCCGGCAGCG
CCCGCAGCGGGCCATTTACACGTCGAGGCTGGCACCTGGCGCGCTCGGGGGCCACTGTAGCGTCTGCCTGCTCCCTGGACTCGCAGGCCT
CGCCTGTGGCGCCTTCCCAGGGCCAGCCTGGGTCACGAGATGCTGTCACTCAGCCAGATCAGTATTGACCCACCAGGGGAGGTGGGGTTT
GGTGAGAGACGCCAGCCTCAGACTTTTTCCCACTGAGGGTCCAGAGAGCGGGGCCACGTGTCACCCACGTCTGCGCTTGGTCACCCGTCC

>In-frame_ENST00000337392_ENST00000291439_TCGA-55-6972_CLPTM1_chr19_45458724_+_AP1M1_chr19_16337231_length(amino acids)=286AA_start in transcript=87_stop in transcript=947
MRCEVGDGAGLAAGAGTRSGKMAAAQEADGARSAVVAAGGGSSGQVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGK
SKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVP
NDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALP

--------------------------------------------------------------
>In-frame_ENST00000337392_ENST00000541844_TCGA-55-6972_CLPTM1_chr19_45458724_+_AP1M1_chr19_16337231_length(transcript)=1424nt_BP=222nt
AAGTGGCCTTCCTGAGAGGCGTGGCTGCGGCACTCTTGCCGGATAGGGTGGCCCGGCGGGGCTAGGAAAGCGTGAAATCTCGCGCGATTG
CGCTGCGAAGTCGGGGACGGGGCGGGGCTGGCGGCGGGGGCGGGGACCCGGAGCGGGAAGATGGCGGCGGCGCAGGAGGCGGACGGGGCC
CGCAGCGCCGTGGTGGCGGCCGGGGGAGGCAGCTCCGGTCAGGTCAGCGCCAACGGCAATGTCCTGCGCAGCGAGATCGTGGGCTCCATC
AAGATGCGAGTCTTCCTCTCGGGCATGCCCGAGCTGCGCCTGGGCCTCAACGACAAGGTCCTCTTTGACAACACGGGCCGCGGCAAAAGC
AAATCCGTGGAGCTGGAGGATGTGAAGTTCCACCAGTGTGTGCGGCTATCACGCTTCGAGAATGACCGCACCATCTCCTTCATCCCACCC
GACGGCGAGTTCGAGCTCATGTCCTACCGTCTCAACACCCACGTCAAGCCTTTGATATGGATCGAGTCGGTGATCGAGAAGCACTCCCAC
AGCCGCATCGAGTACATGATCAAGGCCAAAAGCCAGTTCAAGCGGCGGTCAACAGCCAACAACGTGGAGATCCACATTCCCGTGCCCAAT
GATGCCGACTCACCCAAGTTCAAGACGACGGTGGGGAGCGTTAAGTGGGTCCCCGAGAACAGCGAGATCGTGTGGTCCATCAAGTCCTTC
CCGGGCGGCAAGGAGTACCTGATGCGGGCCCACTTCGGCCTGCCTAGTGTGGAGGCCGAAGACAAGGAGGGCAAGCCCCCGATCAGTGTC
AAGTTCGAGATCCCTTACTTCACTACCTCCGGCATCCAGGTGCGCTACCTGAAGATCATTGAGAAGAGTGGGTACCAGGCCCTGCCCTGG
GTGCGTTATATCACGCAGAATGGAGATTACCAGCTCCGGACCCAGTGAGGGGCTGTCGCAGCCAACACCCCGGCCTCGGGGCTCCTGGTG
GCAGCACCAGGGGACACACCTGCCAAACCCACCAGATGGAGGGGCCCTCCCTGGTCTCTGGCCACCCTCCCAGCCTCTGCCCAGGGACCC
CTGCCTTCCCCAGGCCATCTGCTCTGCCGTCGACACTCGTCTCAGAAGCCCCTTTCCCAGAAGAGGCTGGTCTTCAAGAAGTCTCGTTTC
TTTGCCCCTGAAGTCAGTTTCAGGGGAAGGATGTGAAATTTTTCCGTGTAGAGGTTACAGCCTTTTATGCTGTTGAGCTCCCAGGTACCA
AAAAGCTTGGCCAACGCTTGCCAGCCAGCCAGCTGCAGGTGGCATCTGCCACGAAGGAAGCGCCAGCCTCGCCAGGCCAGCAGGGGCGTC

>In-frame_ENST00000337392_ENST00000541844_TCGA-55-6972_CLPTM1_chr19_45458724_+_AP1M1_chr19_16337231_length(amino acids)=286AA_start in transcript=87_stop in transcript=947
MRCEVGDGAGLAAGAGTRSGKMAAAQEADGARSAVVAAGGGSSGQVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGK
SKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVP
NDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALP

--------------------------------------------------------------
>In-frame_ENST00000337392_ENST00000590756_TCGA-55-6972_CLPTM1_chr19_45458724_+_AP1M1_chr19_16337231_length(transcript)=1424nt_BP=222nt
AAGTGGCCTTCCTGAGAGGCGTGGCTGCGGCACTCTTGCCGGATAGGGTGGCCCGGCGGGGCTAGGAAAGCGTGAAATCTCGCGCGATTG
CGCTGCGAAGTCGGGGACGGGGCGGGGCTGGCGGCGGGGGCGGGGACCCGGAGCGGGAAGATGGCGGCGGCGCAGGAGGCGGACGGGGCC
CGCAGCGCCGTGGTGGCGGCCGGGGGAGGCAGCTCCGGTCAGGTCAGCGCCAACGGCAATGTCCTGCGCAGCGAGATCGTGGGCTCCATC
AAGATGCGAGTCTTCCTCTCGGGCATGCCCGAGCTGCGCCTGGGCCTCAACGACAAGGTCCTCTTTGACAACACGGGCCGCGGCAAAAGC
AAATCCGTGGAGCTGGAGGATGTGAAGTTCCACCAGTGTGTGCGGCTATCACGCTTCGAGAATGACCGCACCATCTCCTTCATCCCACCC
GACGGCGAGTTCGAGCTCATGTCCTACCGTCTCAACACCCACGTCAAGCCTTTGATATGGATCGAGTCGGTGATCGAGAAGCACTCCCAC
AGCCGCATCGAGTACATGATCAAGGCCAAAAGCCAGTTCAAGCGGCGGTCAACAGCCAACAACGTGGAGATCCACATTCCCGTGCCCAAT
GATGCCGACTCACCCAAGTTCAAGACGACGGTGGGGAGCGTTAAGTGGGTCCCCGAGAACAGCGAGATCGTGTGGTCCATCAAGTCCTTC
CCGGGCGGCAAGGAGTACCTGATGCGGGCCCACTTCGGCCTGCCTAGTGTGGAGGCCGAAGACAAGGAGGGCAAGCCCCCGATCAGTGTC
AAGTTCGAGATCCCTTACTTCACTACCTCCGGCATCCAGGTGCGCTACCTGAAGATCATTGAGAAGAGTGGGTACCAGGCCCTGCCCTGG
GTGCGTTATATCACGCAGAATGGAGATTACCAGCTCCGGACCCAGTGAGGGGCTGTCGCAGCCAACACCCCGGCCTCGGGGCTCCTGGTG
GCAGCACCAGGGGACACACCTGCCAAACCCACCAGATGGAGGGGCCCTCCCTGGTCTCTGGCCACCCTCCCAGCCTCTGCCCAGGGACCC
CTGCCTTCCCCAGGCCATCTGCTCTGCCGTCGACACTCGTCTCAGAAGCCCCTTTCCCAGAAGAGGCTGGTCTTCAAGAAGTCTCGTTTC
TTTGCCCCTGAAGTCAGTTTCAGGGGAAGGATGTGAAATTTTTCCGTGTAGAGGTTACAGCCTTTTATGCTGTTGAGCTCCCAGGTACCA
AAAAGCTTGGCCAACGCTTGCCAGCCAGCCAGCTGCAGGTGGCATCTGCCACGAAGGAAGCGCCAGCCTCGCCAGGCCAGCAGGGGCGTC

>In-frame_ENST00000337392_ENST00000590756_TCGA-55-6972_CLPTM1_chr19_45458724_+_AP1M1_chr19_16337231_length(amino acids)=286AA_start in transcript=87_stop in transcript=947
MRCEVGDGAGLAAGAGTRSGKMAAAQEADGARSAVVAAGGGSSGQVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGK
SKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVP
NDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALP

--------------------------------------------------------------
>In-frame_ENST00000337392_ENST00000429941_TCGA-55-6972_CLPTM1_chr19_45458724_+_AP1M1_chr19_16337231_length(transcript)=1138nt_BP=222nt
AAGTGGCCTTCCTGAGAGGCGTGGCTGCGGCACTCTTGCCGGATAGGGTGGCCCGGCGGGGCTAGGAAAGCGTGAAATCTCGCGCGATTG
CGCTGCGAAGTCGGGGACGGGGCGGGGCTGGCGGCGGGGGCGGGGACCCGGAGCGGGAAGATGGCGGCGGCGCAGGAGGCGGACGGGGCC
CGCAGCGCCGTGGTGGCGGCCGGGGGAGGCAGCTCCGGTCAGGTCAGCGCCAACGGCAATGTCCTGCGCAGCGAGATCGTGGGCTCCATC
AAGATGCGAGTCTTCCTCTCGGGCATGCCCGAGCTGCGCCTGGGCCTCAACGACAAGGTCCTCTTTGACAACACGGGCCGCGGCAAAAGC
AAATCCGTGGAGCTGGAGGATGTGAAGTTCCACCAGTGTGTGCGGCTATCACGCTTCGAGAATGACCGCACCATCTCCTTCATCCCACCC
GACGGCGAGTTCGAGCTCATGTCCTACCGTCTCAACACCCACGTCAAGCCTTTGATATGGATCGAGTCGGTGATCGAGAAGCACTCCCAC
AGCCGCATCGAGTACATGATCAAGGGCGGCAAGGAGTACCTGATGCGGGCCCACTTCGGCCTGCCTAGTGTGGAGGCCGAAGACAAGGAG
GGCAAGCCCCCGATCAGTGTCAAGTTCGAGATCCCTTACTTCACTACCTCCGGCATCCAGGTGCGCTACCTGAAGATCATTGAGAAGAGT
GGGTACCAGGCCCTGCCCTGGGTGCGTTATATCACGCAGAATGGAGATTACCAGCTCCGGACCCAGTGAGGGGCTGTCGCAGCCAACACC
CCGGCCTCGGGGCTCCTGGTGGCAGCACCAGGGGACACACCTGCCAAACCCACCAGATGGAGGGGCCCTCCCTGGTCTCTGGCCACCCTC
CCAGCCTCTGCCCAGGGACCCCTGCCTTCCCCAGGCCATCTGCTCTGCCGTCGACACTCGTCTCAGAAGCCCCTTTCCCAGAAGAGGCTG
GTCTTCAAGAAGTCTCGTTTCTTTGCCCCTGAAGTCAGTTTCAGGGGAAGGATGTGAAATTTTTCCGTGTAGAGGTTACAGCCTTTTATG

>In-frame_ENST00000337392_ENST00000429941_TCGA-55-6972_CLPTM1_chr19_45458724_+_AP1M1_chr19_16337231_length(amino acids)=233AA_start in transcript=87_stop in transcript=788
MRCEVGDGAGLAAGAGTRSGKMAAAQEADGARSAVVAAGGGSSGQVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGK
SKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKGGKEYLMRAHFGLPSVEAEDK

--------------------------------------------------------------
>In-frame_ENST00000337392_ENST00000444449_TCGA-55-6972_CLPTM1_chr19_45458724_+_AP1M1_chr19_16337231_length(transcript)=1858nt_BP=222nt
AAGTGGCCTTCCTGAGAGGCGTGGCTGCGGCACTCTTGCCGGATAGGGTGGCCCGGCGGGGCTAGGAAAGCGTGAAATCTCGCGCGATTG
CGCTGCGAAGTCGGGGACGGGGCGGGGCTGGCGGCGGGGGCGGGGACCCGGAGCGGGAAGATGGCGGCGGCGCAGGAGGCGGACGGGGCC
CGCAGCGCCGTGGTGGCGGCCGGGGGAGGCAGCTCCGGTCAGGTCAGCGCCAACGGCAATGTCCTGCGCAGCGAGATCGTGGGCTCCATC
AAGATGCGAGTCTTCCTCTCGGGCATGCCCGAGCTGCGCCTGGGCCTCAACGACAAGGTCCTCTTTGACAACACGGGCCGCGGCAAAAGC
AAATCCGTGGAGCTGGAGGATGTGAAGTTCCACCAGTGTGTGCGGCTATCACGCTTCGAGAATGACCGCACCATCTCCTTCATCCCACCC
GACGGCGAGTTCGAGCTCATGTCCTACCGTCTCAACACCCACGTCAAGCCTTTGATATGGATCGAGTCGGTGATCGAGAAGCACTCCCAC
AGCCGCATCGAGTACATGATCAAGGCCAAAAGCCAGTTCAAGCGGCGGTCAACAGCCAACAACGTGGAGATCCACATTCCCGTGCCCAAT
GATGCCGACTCACCCAAGTTCAAGACGACGGTGGGGAGCGTTAAGTGGGTCCCCGAGAACAGCGAGATCGTGTGGTCCATCAAGTCCTTC
CCGGGCGGCAAGGAGTACCTGATGCGGGCCCACTTCGGCCTGCCTAGTGTGGAGGCCGAAGACAAGGAGGGCAAGCCCCCGATCAGTGTC
AAGTTCGAGATCCCTTACTTCACTACCTCCGGCATCCAGGTGCGCTACCTGAAGATCATTGAGAAGAGTGGGTACCAGGCCCTGCCCTGG
GTGCGTTATATCACGCAGAATGGAGATTACCAGCTCCGGACCCAGTGAGGGGCTGTCGCAGCCAACACCCCGGCCTCGGGGCTCCTGGTG
GCAGCACCAGGGGACACACCTGCCAAACCCACCAGATGGAGGGGCCCTCCCTGGTCTCTGGCCACCCTCCCAGCCTCTGCCCAGGGACCC
CTGCCTTCCCCAGGCCATCTGCTCTGCCGTCGACACTCGTCTCAGAAGCCCCTTTCCCAGAAGAGGCTGGTCTTCAAGAAGTCTCGTTTC
TTTGCCCCTGAAGTCAGTTTCAGGGGAAGGATGTGAAATTTTTCCGTGTAGAGGTTACAGCCTTTTATGCTGTTGAGCTCCCAGGTACCA
AAAAGCTTGGCCAACGCTTGCCAGCCAGCCAGCTGCAGGTGGCATCTGCCACGAAGGAAGCGCCAGCCTCGCCAGGCCAGCAGGGGCGTC
GTTTTGTTGCCATTTTGTTGAACGTTATGGGTTTATGGGTGTTCCTGGAACTTGTCTTTGTGCATTCGTTGCTGTTTGTGTTACCCTCAC
TGTCCCCATGTCCCACCCACGTCCTACGGCACTCAGGAAGCACTTGGTGAGGACGAGCCCTCACCCTTCTTGTCTTCCTTCCCGGCAGCG
CCCGCAGCGGGCCATTTACACGTCGAGGCTGGCACCTGGCGCGCTCGGGGGCCACTGTAGCGTCTGCCTGCTCCCTGGACTCGCAGGCCT
CGCCTGTGGCGCCTTCCCAGGGCCAGCCTGGGTCACGAGATGCTGTCACTCAGCCAGATCAGTATTGACCCACCAGGGGAGGTGGGGTTT
GGTGAGAGACGCCAGCCTCAGACTTTTTCCCACTGAGGGTCCAGAGAGCGGGGCCACGTGTCACCCACGTCTGCGCTTGGTCACCCGTCC

>In-frame_ENST00000337392_ENST00000444449_TCGA-55-6972_CLPTM1_chr19_45458724_+_AP1M1_chr19_16337231_length(amino acids)=286AA_start in transcript=87_stop in transcript=947
MRCEVGDGAGLAAGAGTRSGKMAAAQEADGARSAVVAAGGGSSGQVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGK
SKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVP
NDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALP

--------------------------------------------------------------
>In-frame_ENST00000337392_ENST00000291439_TCGA-55-6972-01A_CLPTM1_chr19_45458724_-_AP1M1_chr19_16337232_length(transcript)=1862nt_BP=222nt
AAGTGGCCTTCCTGAGAGGCGTGGCTGCGGCACTCTTGCCGGATAGGGTGGCCCGGCGGGGCTAGGAAAGCGTGAAATCTCGCGCGATTG
CGCTGCGAAGTCGGGGACGGGGCGGGGCTGGCGGCGGGGGCGGGGACCCGGAGCGGGAAGATGGCGGCGGCGCAGGAGGCGGACGGGGCC
CGCAGCGCCGTGGTGGCGGCCGGGGGAGGCAGCTCCGGTCAGGTCAGCGCCAACGGCAATGTCCTGCGCAGCGAGATCGTGGGCTCCATC
AAGATGCGAGTCTTCCTCTCGGGCATGCCCGAGCTGCGCCTGGGCCTCAACGACAAGGTCCTCTTTGACAACACGGGCCGCGGCAAAAGC
AAATCCGTGGAGCTGGAGGATGTGAAGTTCCACCAGTGTGTGCGGCTATCACGCTTCGAGAATGACCGCACCATCTCCTTCATCCCACCC
GACGGCGAGTTCGAGCTCATGTCCTACCGTCTCAACACCCACGTCAAGCCTTTGATATGGATCGAGTCGGTGATCGAGAAGCACTCCCAC
AGCCGCATCGAGTACATGATCAAGGCCAAAAGCCAGTTCAAGCGGCGGTCAACAGCCAACAACGTGGAGATCCACATTCCCGTGCCCAAT
GATGCCGACTCACCCAAGTTCAAGACGACGGTGGGGAGCGTTAAGTGGGTCCCCGAGAACAGCGAGATCGTGTGGTCCATCAAGTCCTTC
CCGGGCGGCAAGGAGTACCTGATGCGGGCCCACTTCGGCCTGCCTAGTGTGGAGGCCGAAGACAAGGAGGGCAAGCCCCCGATCAGTGTC
AAGTTCGAGATCCCTTACTTCACTACCTCCGGCATCCAGGTGCGCTACCTGAAGATCATTGAGAAGAGTGGGTACCAGGCCCTGCCCTGG
GTGCGTTATATCACGCAGAATGGAGATTACCAGCTCCGGACCCAGTGAGGGGCTGTCGCAGCCAACACCCCGGCCTCGGGGCTCCTGGTG
GCAGCACCAGGGGACACACCTGCCAAACCCACCAGATGGAGGGGCCCTCCCTGGTCTCTGGCCACCCTCCCAGCCTCTGCCCAGGGACCC
CTGCCTTCCCCAGGCCATCTGCTCTGCCGTCGACACTCGTCTCAGAAGCCCCTTTCCCAGAAGAGGCTGGTCTTCAAGAAGTCTCGTTTC
TTTGCCCCTGAAGTCAGTTTCAGGGGAAGGATGTGAAATTTTTCCGTGTAGAGGTTACAGCCTTTTATGCTGTTGAGCTCCCAGGTACCA
AAAAGCTTGGCCAACGCTTGCCAGCCAGCCAGCTGCAGGTGGCATCTGCCACGAAGGAAGCGCCAGCCTCGCCAGGCCAGCAGGGGCGTC
GTTTTGTTGCCATTTTGTTGAACGTTATGGGTTTATGGGTGTTCCTGGAACTTGTCTTTGTGCATTCGTTGCTGTTTGTGTTACCCTCAC
TGTCCCCATGTCCCACCCACGTCCTACGGCACTCAGGAAGCACTTGGTGAGGACGAGCCCTCACCCTTCTTGTCTTCCTTCCCGGCAGCG
CCCGCAGCGGGCCATTTACACGTCGAGGCTGGCACCTGGCGCGCTCGGGGGCCACTGTAGCGTCTGCCTGCTCCCTGGACTCGCAGGCCT
CGCCTGTGGCGCCTTCCCAGGGCCAGCCTGGGTCACGAGATGCTGTCACTCAGCCAGATCAGTATTGACCCACCAGGGGAGGTGGGGTTT
GGTGAGAGACGCCAGCCTCAGACTTTTTCCCACTGAGGGTCCAGAGAGCGGGGCCACGTGTCACCCACGTCTGCGCTTGGTCACCCGTCC

>In-frame_ENST00000337392_ENST00000291439_TCGA-55-6972-01A_CLPTM1_chr19_45458724_-_AP1M1_chr19_16337232_length(amino acids)=286AA_start in transcript=87_stop in transcript=947
MRCEVGDGAGLAAGAGTRSGKMAAAQEADGARSAVVAAGGGSSGQVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGK
SKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVP
NDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALP

--------------------------------------------------------------
>In-frame_ENST00000337392_ENST00000541844_TCGA-55-6972-01A_CLPTM1_chr19_45458724_-_AP1M1_chr19_16337232_length(transcript)=1424nt_BP=222nt
AAGTGGCCTTCCTGAGAGGCGTGGCTGCGGCACTCTTGCCGGATAGGGTGGCCCGGCGGGGCTAGGAAAGCGTGAAATCTCGCGCGATTG
CGCTGCGAAGTCGGGGACGGGGCGGGGCTGGCGGCGGGGGCGGGGACCCGGAGCGGGAAGATGGCGGCGGCGCAGGAGGCGGACGGGGCC
CGCAGCGCCGTGGTGGCGGCCGGGGGAGGCAGCTCCGGTCAGGTCAGCGCCAACGGCAATGTCCTGCGCAGCGAGATCGTGGGCTCCATC
AAGATGCGAGTCTTCCTCTCGGGCATGCCCGAGCTGCGCCTGGGCCTCAACGACAAGGTCCTCTTTGACAACACGGGCCGCGGCAAAAGC
AAATCCGTGGAGCTGGAGGATGTGAAGTTCCACCAGTGTGTGCGGCTATCACGCTTCGAGAATGACCGCACCATCTCCTTCATCCCACCC
GACGGCGAGTTCGAGCTCATGTCCTACCGTCTCAACACCCACGTCAAGCCTTTGATATGGATCGAGTCGGTGATCGAGAAGCACTCCCAC
AGCCGCATCGAGTACATGATCAAGGCCAAAAGCCAGTTCAAGCGGCGGTCAACAGCCAACAACGTGGAGATCCACATTCCCGTGCCCAAT
GATGCCGACTCACCCAAGTTCAAGACGACGGTGGGGAGCGTTAAGTGGGTCCCCGAGAACAGCGAGATCGTGTGGTCCATCAAGTCCTTC
CCGGGCGGCAAGGAGTACCTGATGCGGGCCCACTTCGGCCTGCCTAGTGTGGAGGCCGAAGACAAGGAGGGCAAGCCCCCGATCAGTGTC
AAGTTCGAGATCCCTTACTTCACTACCTCCGGCATCCAGGTGCGCTACCTGAAGATCATTGAGAAGAGTGGGTACCAGGCCCTGCCCTGG
GTGCGTTATATCACGCAGAATGGAGATTACCAGCTCCGGACCCAGTGAGGGGCTGTCGCAGCCAACACCCCGGCCTCGGGGCTCCTGGTG
GCAGCACCAGGGGACACACCTGCCAAACCCACCAGATGGAGGGGCCCTCCCTGGTCTCTGGCCACCCTCCCAGCCTCTGCCCAGGGACCC
CTGCCTTCCCCAGGCCATCTGCTCTGCCGTCGACACTCGTCTCAGAAGCCCCTTTCCCAGAAGAGGCTGGTCTTCAAGAAGTCTCGTTTC
TTTGCCCCTGAAGTCAGTTTCAGGGGAAGGATGTGAAATTTTTCCGTGTAGAGGTTACAGCCTTTTATGCTGTTGAGCTCCCAGGTACCA
AAAAGCTTGGCCAACGCTTGCCAGCCAGCCAGCTGCAGGTGGCATCTGCCACGAAGGAAGCGCCAGCCTCGCCAGGCCAGCAGGGGCGTC

>In-frame_ENST00000337392_ENST00000541844_TCGA-55-6972-01A_CLPTM1_chr19_45458724_-_AP1M1_chr19_16337232_length(amino acids)=286AA_start in transcript=87_stop in transcript=947
MRCEVGDGAGLAAGAGTRSGKMAAAQEADGARSAVVAAGGGSSGQVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGK
SKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVP
NDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALP

--------------------------------------------------------------
>In-frame_ENST00000337392_ENST00000590756_TCGA-55-6972-01A_CLPTM1_chr19_45458724_-_AP1M1_chr19_16337232_length(transcript)=1424nt_BP=222nt
AAGTGGCCTTCCTGAGAGGCGTGGCTGCGGCACTCTTGCCGGATAGGGTGGCCCGGCGGGGCTAGGAAAGCGTGAAATCTCGCGCGATTG
CGCTGCGAAGTCGGGGACGGGGCGGGGCTGGCGGCGGGGGCGGGGACCCGGAGCGGGAAGATGGCGGCGGCGCAGGAGGCGGACGGGGCC
CGCAGCGCCGTGGTGGCGGCCGGGGGAGGCAGCTCCGGTCAGGTCAGCGCCAACGGCAATGTCCTGCGCAGCGAGATCGTGGGCTCCATC
AAGATGCGAGTCTTCCTCTCGGGCATGCCCGAGCTGCGCCTGGGCCTCAACGACAAGGTCCTCTTTGACAACACGGGCCGCGGCAAAAGC
AAATCCGTGGAGCTGGAGGATGTGAAGTTCCACCAGTGTGTGCGGCTATCACGCTTCGAGAATGACCGCACCATCTCCTTCATCCCACCC
GACGGCGAGTTCGAGCTCATGTCCTACCGTCTCAACACCCACGTCAAGCCTTTGATATGGATCGAGTCGGTGATCGAGAAGCACTCCCAC
AGCCGCATCGAGTACATGATCAAGGCCAAAAGCCAGTTCAAGCGGCGGTCAACAGCCAACAACGTGGAGATCCACATTCCCGTGCCCAAT
GATGCCGACTCACCCAAGTTCAAGACGACGGTGGGGAGCGTTAAGTGGGTCCCCGAGAACAGCGAGATCGTGTGGTCCATCAAGTCCTTC
CCGGGCGGCAAGGAGTACCTGATGCGGGCCCACTTCGGCCTGCCTAGTGTGGAGGCCGAAGACAAGGAGGGCAAGCCCCCGATCAGTGTC
AAGTTCGAGATCCCTTACTTCACTACCTCCGGCATCCAGGTGCGCTACCTGAAGATCATTGAGAAGAGTGGGTACCAGGCCCTGCCCTGG
GTGCGTTATATCACGCAGAATGGAGATTACCAGCTCCGGACCCAGTGAGGGGCTGTCGCAGCCAACACCCCGGCCTCGGGGCTCCTGGTG
GCAGCACCAGGGGACACACCTGCCAAACCCACCAGATGGAGGGGCCCTCCCTGGTCTCTGGCCACCCTCCCAGCCTCTGCCCAGGGACCC
CTGCCTTCCCCAGGCCATCTGCTCTGCCGTCGACACTCGTCTCAGAAGCCCCTTTCCCAGAAGAGGCTGGTCTTCAAGAAGTCTCGTTTC
TTTGCCCCTGAAGTCAGTTTCAGGGGAAGGATGTGAAATTTTTCCGTGTAGAGGTTACAGCCTTTTATGCTGTTGAGCTCCCAGGTACCA
AAAAGCTTGGCCAACGCTTGCCAGCCAGCCAGCTGCAGGTGGCATCTGCCACGAAGGAAGCGCCAGCCTCGCCAGGCCAGCAGGGGCGTC

>In-frame_ENST00000337392_ENST00000590756_TCGA-55-6972-01A_CLPTM1_chr19_45458724_-_AP1M1_chr19_16337232_length(amino acids)=286AA_start in transcript=87_stop in transcript=947
MRCEVGDGAGLAAGAGTRSGKMAAAQEADGARSAVVAAGGGSSGQVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGK
SKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVP
NDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALP

--------------------------------------------------------------
>In-frame_ENST00000337392_ENST00000429941_TCGA-55-6972-01A_CLPTM1_chr19_45458724_-_AP1M1_chr19_16337232_length(transcript)=1138nt_BP=222nt
AAGTGGCCTTCCTGAGAGGCGTGGCTGCGGCACTCTTGCCGGATAGGGTGGCCCGGCGGGGCTAGGAAAGCGTGAAATCTCGCGCGATTG
CGCTGCGAAGTCGGGGACGGGGCGGGGCTGGCGGCGGGGGCGGGGACCCGGAGCGGGAAGATGGCGGCGGCGCAGGAGGCGGACGGGGCC
CGCAGCGCCGTGGTGGCGGCCGGGGGAGGCAGCTCCGGTCAGGTCAGCGCCAACGGCAATGTCCTGCGCAGCGAGATCGTGGGCTCCATC
AAGATGCGAGTCTTCCTCTCGGGCATGCCCGAGCTGCGCCTGGGCCTCAACGACAAGGTCCTCTTTGACAACACGGGCCGCGGCAAAAGC
AAATCCGTGGAGCTGGAGGATGTGAAGTTCCACCAGTGTGTGCGGCTATCACGCTTCGAGAATGACCGCACCATCTCCTTCATCCCACCC
GACGGCGAGTTCGAGCTCATGTCCTACCGTCTCAACACCCACGTCAAGCCTTTGATATGGATCGAGTCGGTGATCGAGAAGCACTCCCAC
AGCCGCATCGAGTACATGATCAAGGGCGGCAAGGAGTACCTGATGCGGGCCCACTTCGGCCTGCCTAGTGTGGAGGCCGAAGACAAGGAG
GGCAAGCCCCCGATCAGTGTCAAGTTCGAGATCCCTTACTTCACTACCTCCGGCATCCAGGTGCGCTACCTGAAGATCATTGAGAAGAGT
GGGTACCAGGCCCTGCCCTGGGTGCGTTATATCACGCAGAATGGAGATTACCAGCTCCGGACCCAGTGAGGGGCTGTCGCAGCCAACACC
CCGGCCTCGGGGCTCCTGGTGGCAGCACCAGGGGACACACCTGCCAAACCCACCAGATGGAGGGGCCCTCCCTGGTCTCTGGCCACCCTC
CCAGCCTCTGCCCAGGGACCCCTGCCTTCCCCAGGCCATCTGCTCTGCCGTCGACACTCGTCTCAGAAGCCCCTTTCCCAGAAGAGGCTG
GTCTTCAAGAAGTCTCGTTTCTTTGCCCCTGAAGTCAGTTTCAGGGGAAGGATGTGAAATTTTTCCGTGTAGAGGTTACAGCCTTTTATG

>In-frame_ENST00000337392_ENST00000429941_TCGA-55-6972-01A_CLPTM1_chr19_45458724_-_AP1M1_chr19_16337232_length(amino acids)=233AA_start in transcript=87_stop in transcript=788
MRCEVGDGAGLAAGAGTRSGKMAAAQEADGARSAVVAAGGGSSGQVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGK
SKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKGGKEYLMRAHFGLPSVEAEDK

--------------------------------------------------------------
>In-frame_ENST00000337392_ENST00000444449_TCGA-55-6972-01A_CLPTM1_chr19_45458724_-_AP1M1_chr19_16337232_length(transcript)=1858nt_BP=222nt
AAGTGGCCTTCCTGAGAGGCGTGGCTGCGGCACTCTTGCCGGATAGGGTGGCCCGGCGGGGCTAGGAAAGCGTGAAATCTCGCGCGATTG
CGCTGCGAAGTCGGGGACGGGGCGGGGCTGGCGGCGGGGGCGGGGACCCGGAGCGGGAAGATGGCGGCGGCGCAGGAGGCGGACGGGGCC
CGCAGCGCCGTGGTGGCGGCCGGGGGAGGCAGCTCCGGTCAGGTCAGCGCCAACGGCAATGTCCTGCGCAGCGAGATCGTGGGCTCCATC
AAGATGCGAGTCTTCCTCTCGGGCATGCCCGAGCTGCGCCTGGGCCTCAACGACAAGGTCCTCTTTGACAACACGGGCCGCGGCAAAAGC
AAATCCGTGGAGCTGGAGGATGTGAAGTTCCACCAGTGTGTGCGGCTATCACGCTTCGAGAATGACCGCACCATCTCCTTCATCCCACCC
GACGGCGAGTTCGAGCTCATGTCCTACCGTCTCAACACCCACGTCAAGCCTTTGATATGGATCGAGTCGGTGATCGAGAAGCACTCCCAC
AGCCGCATCGAGTACATGATCAAGGCCAAAAGCCAGTTCAAGCGGCGGTCAACAGCCAACAACGTGGAGATCCACATTCCCGTGCCCAAT
GATGCCGACTCACCCAAGTTCAAGACGACGGTGGGGAGCGTTAAGTGGGTCCCCGAGAACAGCGAGATCGTGTGGTCCATCAAGTCCTTC
CCGGGCGGCAAGGAGTACCTGATGCGGGCCCACTTCGGCCTGCCTAGTGTGGAGGCCGAAGACAAGGAGGGCAAGCCCCCGATCAGTGTC
AAGTTCGAGATCCCTTACTTCACTACCTCCGGCATCCAGGTGCGCTACCTGAAGATCATTGAGAAGAGTGGGTACCAGGCCCTGCCCTGG
GTGCGTTATATCACGCAGAATGGAGATTACCAGCTCCGGACCCAGTGAGGGGCTGTCGCAGCCAACACCCCGGCCTCGGGGCTCCTGGTG
GCAGCACCAGGGGACACACCTGCCAAACCCACCAGATGGAGGGGCCCTCCCTGGTCTCTGGCCACCCTCCCAGCCTCTGCCCAGGGACCC
CTGCCTTCCCCAGGCCATCTGCTCTGCCGTCGACACTCGTCTCAGAAGCCCCTTTCCCAGAAGAGGCTGGTCTTCAAGAAGTCTCGTTTC
TTTGCCCCTGAAGTCAGTTTCAGGGGAAGGATGTGAAATTTTTCCGTGTAGAGGTTACAGCCTTTTATGCTGTTGAGCTCCCAGGTACCA
AAAAGCTTGGCCAACGCTTGCCAGCCAGCCAGCTGCAGGTGGCATCTGCCACGAAGGAAGCGCCAGCCTCGCCAGGCCAGCAGGGGCGTC
GTTTTGTTGCCATTTTGTTGAACGTTATGGGTTTATGGGTGTTCCTGGAACTTGTCTTTGTGCATTCGTTGCTGTTTGTGTTACCCTCAC
TGTCCCCATGTCCCACCCACGTCCTACGGCACTCAGGAAGCACTTGGTGAGGACGAGCCCTCACCCTTCTTGTCTTCCTTCCCGGCAGCG
CCCGCAGCGGGCCATTTACACGTCGAGGCTGGCACCTGGCGCGCTCGGGGGCCACTGTAGCGTCTGCCTGCTCCCTGGACTCGCAGGCCT
CGCCTGTGGCGCCTTCCCAGGGCCAGCCTGGGTCACGAGATGCTGTCACTCAGCCAGATCAGTATTGACCCACCAGGGGAGGTGGGGTTT
GGTGAGAGACGCCAGCCTCAGACTTTTTCCCACTGAGGGTCCAGAGAGCGGGGCCACGTGTCACCCACGTCTGCGCTTGGTCACCCGTCC

>In-frame_ENST00000337392_ENST00000444449_TCGA-55-6972-01A_CLPTM1_chr19_45458724_-_AP1M1_chr19_16337232_length(amino acids)=286AA_start in transcript=87_stop in transcript=947
MRCEVGDGAGLAAGAGTRSGKMAAAQEADGARSAVVAAGGGSSGQVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGK
SKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVP
NDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CLPTM1-AP1M1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CLPTM1-AP1M1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CLPTM1-AP1M1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCLPTM1C0030297Pancreatic Neoplasm1CTD_human
HgeneCLPTM1C0346647Malignant neoplasm of pancreas1CTD_human