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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CLSTN1-SPA17 (FusionGDB2 ID:17373)

Fusion Gene Summary for CLSTN1-SPA17

check button Fusion gene summary
Fusion gene informationFusion gene name: CLSTN1-SPA17
Fusion gene ID: 17373
HgeneTgene
Gene symbol

CLSTN1

SPA17

Gene ID

22883

53340

Gene namecalsyntenin 1sperm autoantigenic protein 17
SynonymsALC-ALPHA|CDHR12|CST-1|CSTN1|PIK3CD|XB31alpha|alcalpha1|alcalpha2CT22|SP17|SP17-1
Cytomap

1p36.22

11q24.2

Type of geneprotein-codingprotein-coding
Descriptioncalsyntenin-1alcadein-alphaalzheimer-related cadherin-like proteincadherin-related family member 12non-classical cadherin XB31alphasperm surface protein Sp17cancer/testis antigen 22sperm protein 17
Modification date2020031320200313
UniProtAcc

O94985

.
Ensembl transtripts involved in fusion geneENST00000377298, ENST00000361311, 
ENST00000377288, ENST00000477264, 
ENST00000227135, ENST00000532692, 
ENST00000524614, 
Fusion gene scores* DoF score12 X 15 X 7=12603 X 5 X 3=45
# samples 204
** MAII scorelog2(20/1260*10)=-2.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/45*10)=-0.169925001442312
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CLSTN1 [Title/Abstract] AND SPA17 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCLSTN1(9883701)-SPA17(124561592), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CLSTN1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across SPA17 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1550-01ACLSTN1chr1

9883701

-SPA17chr11

124561592

+
ChimerDB4OVTCGA-24-1550CLSTN1chr1

9883700

-SPA17chr11

124561591

+
ChimerDB4OVTCGA-24-1550-01ACLSTN1chr1

9883701

-SPA17chr11

124561592

+


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Fusion Gene ORF analysis for CLSTN1-SPA17

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000377298ENST00000227135CLSTN1chr1

9883701

-SPA17chr11

124561592

+
In-frameENST00000377298ENST00000532692CLSTN1chr1

9883701

-SPA17chr11

124561592

+
5CDS-3UTRENST00000377298ENST00000524614CLSTN1chr1

9883701

-SPA17chr11

124561592

+
In-frameENST00000361311ENST00000227135CLSTN1chr1

9883701

-SPA17chr11

124561592

+
In-frameENST00000361311ENST00000532692CLSTN1chr1

9883701

-SPA17chr11

124561592

+
5CDS-3UTRENST00000361311ENST00000524614CLSTN1chr1

9883701

-SPA17chr11

124561592

+
In-frameENST00000377288ENST00000227135CLSTN1chr1

9883701

-SPA17chr11

124561592

+
In-frameENST00000377288ENST00000532692CLSTN1chr1

9883701

-SPA17chr11

124561592

+
5CDS-3UTRENST00000377288ENST00000524614CLSTN1chr1

9883701

-SPA17chr11

124561592

+
intron-3CDSENST00000477264ENST00000227135CLSTN1chr1

9883701

-SPA17chr11

124561592

+
intron-3CDSENST00000477264ENST00000532692CLSTN1chr1

9883701

-SPA17chr11

124561592

+
intron-3UTRENST00000477264ENST00000524614CLSTN1chr1

9883701

-SPA17chr11

124561592

+
In-frameENST00000377298ENST00000227135CLSTN1chr1

9883700

-SPA17chr11

124561591

+
In-frameENST00000377298ENST00000532692CLSTN1chr1

9883700

-SPA17chr11

124561591

+
5CDS-3UTRENST00000377298ENST00000524614CLSTN1chr1

9883700

-SPA17chr11

124561591

+
In-frameENST00000361311ENST00000227135CLSTN1chr1

9883700

-SPA17chr11

124561591

+
In-frameENST00000361311ENST00000532692CLSTN1chr1

9883700

-SPA17chr11

124561591

+
5CDS-3UTRENST00000361311ENST00000524614CLSTN1chr1

9883700

-SPA17chr11

124561591

+
In-frameENST00000377288ENST00000227135CLSTN1chr1

9883700

-SPA17chr11

124561591

+
In-frameENST00000377288ENST00000532692CLSTN1chr1

9883700

-SPA17chr11

124561591

+
5CDS-3UTRENST00000377288ENST00000524614CLSTN1chr1

9883700

-SPA17chr11

124561591

+
intron-3CDSENST00000477264ENST00000227135CLSTN1chr1

9883700

-SPA17chr11

124561591

+
intron-3CDSENST00000477264ENST00000532692CLSTN1chr1

9883700

-SPA17chr11

124561591

+
intron-3UTRENST00000477264ENST00000524614CLSTN1chr1

9883700

-SPA17chr11

124561591

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000377298CLSTN1chr19883701-ENST00000227135SPA17chr11124561592+13308844880163
ENST00000377298CLSTN1chr19883701-ENST00000532692SPA17chr11124561592+4187884703215162
ENST00000361311CLSTN1chr19883701-ENST00000227135SPA17chr11124561592+78834226358110
ENST00000361311CLSTN1chr19883701-ENST00000532692SPA17chr11124561592+364534221592524121
ENST00000377288CLSTN1chr19883701-ENST00000227135SPA17chr11124561592+13308844880163
ENST00000377288CLSTN1chr19883701-ENST00000532692SPA17chr11124561592+4187884703215162
ENST00000377298CLSTN1chr19883700-ENST00000227135SPA17chr11124561591+13308844880163
ENST00000377298CLSTN1chr19883700-ENST00000532692SPA17chr11124561591+4187884703215162
ENST00000361311CLSTN1chr19883700-ENST00000227135SPA17chr11124561591+78834226358110
ENST00000361311CLSTN1chr19883700-ENST00000532692SPA17chr11124561591+364534221592524121
ENST00000377288CLSTN1chr19883700-ENST00000227135SPA17chr11124561591+13308844880163
ENST00000377288CLSTN1chr19883700-ENST00000532692SPA17chr11124561591+4187884703215162

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000377298ENST00000227135CLSTN1chr19883701-SPA17chr11124561592+0.8225720.17742802
ENST00000377298ENST00000532692CLSTN1chr19883701-SPA17chr11124561592+0.803125740.19687432
ENST00000361311ENST00000227135CLSTN1chr19883701-SPA17chr11124561592+0.794939460.20506059
ENST00000361311ENST00000532692CLSTN1chr19883701-SPA17chr11124561592+0.721111540.27888843
ENST00000377288ENST00000227135CLSTN1chr19883701-SPA17chr11124561592+0.8225720.17742802
ENST00000377288ENST00000532692CLSTN1chr19883701-SPA17chr11124561592+0.803125740.19687432
ENST00000377298ENST00000227135CLSTN1chr19883700-SPA17chr11124561591+0.8225720.17742802
ENST00000377298ENST00000532692CLSTN1chr19883700-SPA17chr11124561591+0.803125740.19687432
ENST00000361311ENST00000227135CLSTN1chr19883700-SPA17chr11124561591+0.794939460.20506059
ENST00000361311ENST00000532692CLSTN1chr19883700-SPA17chr11124561591+0.721111540.27888843
ENST00000377288ENST00000227135CLSTN1chr19883700-SPA17chr11124561591+0.8225720.17742802
ENST00000377288ENST00000532692CLSTN1chr19883700-SPA17chr11124561591+0.803125740.19687432

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Fusion Genomic Features for CLSTN1-SPA17


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CLSTN1chr19883700-SPA17chr11124561591+5.59E-091
CLSTN1chr19883700-SPA17chr11124561591+5.59E-091
CLSTN1chr19883700-SPA17chr11124561591+5.59E-091
CLSTN1chr19883700-SPA17chr11124561591+5.59E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CLSTN1-SPA17


check button Go to

FGviewer for the breakpoints of chr1:9883701-chr11:124561592

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CLSTN1

O94985

.
FUNCTION: Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals (By similarity). {ECO:0000250, ECO:0000269|PubMed:12972431}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSPA17chr1:9883700chr11:124561591ENST0000022713525114_14375.0152.0DomainIQ
TgeneSPA17chr1:9883700chr11:124561591ENST0000053269214114_14375.0152.0DomainIQ
TgeneSPA17chr1:9883701chr11:124561592ENST0000022713525114_14375.0152.0DomainIQ
TgeneSPA17chr1:9883701chr11:124561592ENST0000053269214114_14375.0152.0DomainIQ

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000361311-118916_95930.333333333333332972.0Compositional biasNote=Glu-rich (highly acidic)
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000377298-119916_95930.333333333333332982.0Compositional biasNote=Glu-rich (highly acidic)
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000361311-118916_95930.333333333333332972.0Compositional biasNote=Glu-rich (highly acidic)
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000377298-119916_95930.333333333333332982.0Compositional biasNote=Glu-rich (highly acidic)
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000361311-118165_26530.333333333333332972.0DomainCadherin 2
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000361311-11838_16430.333333333333332972.0DomainCadherin 1
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000377298-119165_26530.333333333333332982.0DomainCadherin 2
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000377298-11938_16430.333333333333332982.0DomainCadherin 1
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000361311-118165_26530.333333333333332972.0DomainCadherin 2
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000361311-11838_16430.333333333333332972.0DomainCadherin 1
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000377298-119165_26530.333333333333332982.0DomainCadherin 2
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000377298-11938_16430.333333333333332982.0DomainCadherin 1
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000361311-11829_85930.333333333333332972.0Topological domainExtracellular
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000361311-118881_98130.333333333333332972.0Topological domainCytoplasmic
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000377298-11929_85930.333333333333332982.0Topological domainExtracellular
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000377298-119881_98130.333333333333332982.0Topological domainCytoplasmic
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000361311-11829_85930.333333333333332972.0Topological domainExtracellular
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000361311-118881_98130.333333333333332972.0Topological domainCytoplasmic
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000377298-11929_85930.333333333333332982.0Topological domainExtracellular
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000377298-119881_98130.333333333333332982.0Topological domainCytoplasmic
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000361311-118860_88030.333333333333332972.0TransmembraneHelical
HgeneCLSTN1chr1:9883700chr11:124561591ENST00000377298-119860_88030.333333333333332982.0TransmembraneHelical
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000361311-118860_88030.333333333333332972.0TransmembraneHelical
HgeneCLSTN1chr1:9883701chr11:124561592ENST00000377298-119860_88030.333333333333332982.0TransmembraneHelical


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Fusion Gene Sequence for CLSTN1-SPA17


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000377298_ENST00000227135_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(transcript)=1330nt_BP=884nt
GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG
AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA
GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC
CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC
CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC
CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC
CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG
CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT
AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC
TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG
AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA
AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA
GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT
CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG

>In-frame_ENST00000377298_ENST00000227135_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(amino acids)=163AA_start in transcript=488_stop in transcript=0
MGSDARRARGGPWERAGPGGAGERSGGSARGGPGSGRAPPSPSAPPGARARGDAPGVGSERPGGARGTVSLSLAADGEPQLRVPTRAPGL

--------------------------------------------------------------
>In-frame_ENST00000377298_ENST00000532692_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(transcript)=4187nt_BP=884nt
GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG
AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA
GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC
CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC
CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC
CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC
CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG
CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT
AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC
TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG
AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA
AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA
GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT
CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG
TTTAATAAGCATACCATTGAAACATGCCACTTGAAGATTTCTCTGAGATCATGAGTTTGTTTACACTTGTCTCAAGCCTATCTATAGAGA
CCCTTGGATTTAGAATTATAGAACTAAAGTATCTGAGATTACAGAGATCTCAGAGGTTATGTGTTCTAACTATTATCAAATGAATAAATC
CTCTCTATCACATCCCCCAAAAATGTTCTTTAGCTCCTGTTTCACTCCTAGTGGTAAAGAATTTCACTGCTTTTTAAGGATAGTCTATTT
AATTTTGGAATTTTTAGAAAGATAAGCTGGGACAAAAATCTGCCTCCTTCAGCCTGGCCAACATGGTGAAACCCCATGTCTACTAAAAGT
ACAAAAATTGGCCAGGCGTGGTGCGCACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGTGGA
GGCTGCAGTAAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAACAAAACAAAACAAAAAAAAG
CCTCTGCCTCCTTGTAAGTTTAACCCACTGGTTTTCATTTATCATACATGTATTCAATCATTTATTGAAAATGTATTGAGTACTATTCAT
GTGCTGGGAATTAGTAGTGAATACTTGTTCTTACACTCATACAACTTACAATGCTTTATTGTTTTGCTCTCCAGAACCACACAGAACAAG
ACTAATAACATCATATTGTAAAAAGCAAAAGCTATCATATCATGCTGCCTTCTTCAGTTAAAACTTCCCAAGTTTTTAAATATACAATGG
TAATGCCTGTTTAACAAACTCAGAGGCTTTATCTCTTTTATGTTTTCAATGATTCATTCAAATCCCTAGTGCCTTAGTTTTAGAAAGTTC
CGTCTCTCCTTTTTGAGGCCTCTCCACCCTTGATTGTCCAAGAAACTGAGGGTTCATGTCTTAGACCAAAGGGTGCAGTTCTCTTCCCAA
TACAAAAGGTAGAAAGTGGAGTCTTACCATTTAGTTAATGCTGTTGCCTTCTACCATAATGTTGTAGCATAGTCCAGCAGACTGAGGTGA
TTCTCTGGCTGGTTCCAATTCCTGCCTGCACCATAGTGGATGGCCCATGATTTAGTTCCAGGATTACATCTCTCTTGGTTTATAGTCACA
AAGCCAGTGTTCCCCCAAAGCTTAAAAACAAGCCAGGATGGCTCAGTCCTGAGGAGATTCTAAAACCAGGTCTATGTTGTCACAACAAAT
ACTCTCCTACAAACACTTTGATCCTTGTCCTAGGCTTAGACATGCTCTTTCTGCAAAGCAGTTTTATTTCAGGTGCCTCACTGCCCTTCC
CTGGCACTGAGCCTTTATCAGGCTCTGCAACAGAGGTTCCCCCAAGTGATCGCCACTCAAACACAGTTGATTCACACCAACCCTTTCAAG
GTTGTGGCTTTCATTCTCTAATGTCCACTCATACAGGCAGCCTTTCTCCTTCCAAAATCTTGCTGCCACTGTAGAGAGTTTCATGCTAGC
TAAACACAAGTCTCTAATATCCCCCTTCCTCTCCTCCTTAACCCCTCTCCTCCAGGCTTACAGAGGAAAAGAAATCAGTTCTCCTCCAGG
ATTCCAGCTGTTCGTCCCTCCCATTCCACTGAAAGCACCAGCTTCTAACACCTTCCCCTCTCAGACAGAGCCATCCTGCTTAGCGGATTG
TCAAGGGGGGACCCAGAATTTATGCAAAGACTTAGATTCCCTGACCTGGAGAGATCAGAAGAGGAAAAAAGGGATTTTTTCCCTAGTGAG
TATATAGCAGGAAAAAAAAAAAAGATGAGTTAGCTTTTTCAGTAATTCTCCTGTTATACACATAAAGTGACTAGCACTATGCATTCCATA
CACACACACACACACACACAGATCTCATGGTAGTGATATTGGTAGTGAAGGAGGAAAAGGAAAAGGTGAGCAATGGATGTGATATTATGA
GAACAACACATATGAATGACACTTTATTAGAACTTATCTGGTTTTCCTCTTATCTCTCTGGCTGTTCCTTCTCAATTCCCTTCACTGGTA
ACTCTTCAACTCCCCAACCACTAAATGCTAAGTGCCCTTAGGCTCAGTCTTTCGACCCCATTTCTACACTCACTTGATTTCCTGCAGTTT
CATAGCTTTAAAATCCAATCTTCTTAATGATCACTCCCAGACCTTTCTCTCCTCTGCCTGCGAACTTCTATATTCAACTGCCTACATAAC
ATCCCCATTTGGATGTCTATAGGCATCTCAAAAGTAACATATAAAAAATGAATCCTGATATTGCCCCCAAATCTGAAACTTCCCCCACAC
CCAAGTTTTTCCATTCAAAAATGGCTGCTCCATTCTTCCATTTGCTCAGGCCAAAAACCTTGGATTCATCTTTAATGCGTCACTTTCTTT
CACACCCCATATACAATCTATCAGCAAAACCTGTGGGCTGTACCTATAAAATAATACTCAGAATCTGCCTACTTCTAACCACTTCCATTG
TTACCGCCTTGGTCCTAGTTCCCATGATAGCCTTGTGAATTATTGCAATAACCTATATTGGCCAGTGATTATCTCACTACTACTGCACAA
CCCATTCCAAAGTTAGTGGTTTAAGACAATTATATTTTCTCCTGGGTCTGTAGGTCAGTGGTAATGTAGCTAAGCTAGGCTGGACTACAA
TCTCAAGGTTAGGTTCAGGTCAGCTCTAAGCTGTGGGTTTGTGGGCTGACAGGAAGGTCTGCTTCAGGCTGTGGGCCCAAGGGTCAGCTG
CAGCACAGTGCCTCTGCTTCACGTGTCCTTTTCTGAGCCCCTGCTGAAAGACGTTATCCAGGACAAGCTCTTCTCATGCTGGTCACAGAA

>In-frame_ENST00000377298_ENST00000532692_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(amino acids)=162AA_start in transcript=703_stop in transcript=215
MLRGAGSSGGPRRSRRRRRRDAGPRAQDAAPSPPQSSVLLKAAAATKMAAALSLGSGEGTRPGAGWRREGRGWGATRGARAADPGSARAR

--------------------------------------------------------------
>In-frame_ENST00000361311_ENST00000227135_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(transcript)=788nt_BP=342nt
GAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCGCG
CGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCTAG
AGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGCTC
CCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTGAG
AAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATAAG
GAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATAGT
CTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTTCT
TATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTGTT

>In-frame_ENST00000361311_ENST00000227135_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(amino acids)=110AA_start in transcript=26_stop in transcript=358
MLPLPSARRCSEAGRAPRPERAAQRHGGGGGGSSLDPRSSPRRGAASPRPLEPRELRELRSASRAPPCRSRPGLAMLRRPAPALAPAARL

--------------------------------------------------------------
>In-frame_ENST00000361311_ENST00000532692_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(transcript)=3645nt_BP=342nt
GAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCGCG
CGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCTAG
AGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGCTC
CCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTGAG
AAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATAAG
GAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATAGT
CTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTTCT
TATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTGTT
TAATAAGCATACCATTGAAACATGCCACTTGAAGATTTCTCTGAGATCATGAGTTTGTTTACACTTGTCTCAAGCCTATCTATAGAGACC
CTTGGATTTAGAATTATAGAACTAAAGTATCTGAGATTACAGAGATCTCAGAGGTTATGTGTTCTAACTATTATCAAATGAATAAATCCT
CTCTATCACATCCCCCAAAAATGTTCTTTAGCTCCTGTTTCACTCCTAGTGGTAAAGAATTTCACTGCTTTTTAAGGATAGTCTATTTAA
TTTTGGAATTTTTAGAAAGATAAGCTGGGACAAAAATCTGCCTCCTTCAGCCTGGCCAACATGGTGAAACCCCATGTCTACTAAAAGTAC
AAAAATTGGCCAGGCGTGGTGCGCACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGTGGAGG
CTGCAGTAAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAACAAAACAAAACAAAAAAAAGCC
TCTGCCTCCTTGTAAGTTTAACCCACTGGTTTTCATTTATCATACATGTATTCAATCATTTATTGAAAATGTATTGAGTACTATTCATGT
GCTGGGAATTAGTAGTGAATACTTGTTCTTACACTCATACAACTTACAATGCTTTATTGTTTTGCTCTCCAGAACCACACAGAACAAGAC
TAATAACATCATATTGTAAAAAGCAAAAGCTATCATATCATGCTGCCTTCTTCAGTTAAAACTTCCCAAGTTTTTAAATATACAATGGTA
ATGCCTGTTTAACAAACTCAGAGGCTTTATCTCTTTTATGTTTTCAATGATTCATTCAAATCCCTAGTGCCTTAGTTTTAGAAAGTTCCG
TCTCTCCTTTTTGAGGCCTCTCCACCCTTGATTGTCCAAGAAACTGAGGGTTCATGTCTTAGACCAAAGGGTGCAGTTCTCTTCCCAATA
CAAAAGGTAGAAAGTGGAGTCTTACCATTTAGTTAATGCTGTTGCCTTCTACCATAATGTTGTAGCATAGTCCAGCAGACTGAGGTGATT
CTCTGGCTGGTTCCAATTCCTGCCTGCACCATAGTGGATGGCCCATGATTTAGTTCCAGGATTACATCTCTCTTGGTTTATAGTCACAAA
GCCAGTGTTCCCCCAAAGCTTAAAAACAAGCCAGGATGGCTCAGTCCTGAGGAGATTCTAAAACCAGGTCTATGTTGTCACAACAAATAC
TCTCCTACAAACACTTTGATCCTTGTCCTAGGCTTAGACATGCTCTTTCTGCAAAGCAGTTTTATTTCAGGTGCCTCACTGCCCTTCCCT
GGCACTGAGCCTTTATCAGGCTCTGCAACAGAGGTTCCCCCAAGTGATCGCCACTCAAACACAGTTGATTCACACCAACCCTTTCAAGGT
TGTGGCTTTCATTCTCTAATGTCCACTCATACAGGCAGCCTTTCTCCTTCCAAAATCTTGCTGCCACTGTAGAGAGTTTCATGCTAGCTA
AACACAAGTCTCTAATATCCCCCTTCCTCTCCTCCTTAACCCCTCTCCTCCAGGCTTACAGAGGAAAAGAAATCAGTTCTCCTCCAGGAT
TCCAGCTGTTCGTCCCTCCCATTCCACTGAAAGCACCAGCTTCTAACACCTTCCCCTCTCAGACAGAGCCATCCTGCTTAGCGGATTGTC
AAGGGGGGACCCAGAATTTATGCAAAGACTTAGATTCCCTGACCTGGAGAGATCAGAAGAGGAAAAAAGGGATTTTTTCCCTAGTGAGTA
TATAGCAGGAAAAAAAAAAAAGATGAGTTAGCTTTTTCAGTAATTCTCCTGTTATACACATAAAGTGACTAGCACTATGCATTCCATACA
CACACACACACACACACAGATCTCATGGTAGTGATATTGGTAGTGAAGGAGGAAAAGGAAAAGGTGAGCAATGGATGTGATATTATGAGA
ACAACACATATGAATGACACTTTATTAGAACTTATCTGGTTTTCCTCTTATCTCTCTGGCTGTTCCTTCTCAATTCCCTTCACTGGTAAC
TCTTCAACTCCCCAACCACTAAATGCTAAGTGCCCTTAGGCTCAGTCTTTCGACCCCATTTCTACACTCACTTGATTTCCTGCAGTTTCA
TAGCTTTAAAATCCAATCTTCTTAATGATCACTCCCAGACCTTTCTCTCCTCTGCCTGCGAACTTCTATATTCAACTGCCTACATAACAT
CCCCATTTGGATGTCTATAGGCATCTCAAAAGTAACATATAAAAAATGAATCCTGATATTGCCCCCAAATCTGAAACTTCCCCCACACCC
AAGTTTTTCCATTCAAAAATGGCTGCTCCATTCTTCCATTTGCTCAGGCCAAAAACCTTGGATTCATCTTTAATGCGTCACTTTCTTTCA
CACCCCATATACAATCTATCAGCAAAACCTGTGGGCTGTACCTATAAAATAATACTCAGAATCTGCCTACTTCTAACCACTTCCATTGTT
ACCGCCTTGGTCCTAGTTCCCATGATAGCCTTGTGAATTATTGCAATAACCTATATTGGCCAGTGATTATCTCACTACTACTGCACAACC
CATTCCAAAGTTAGTGGTTTAAGACAATTATATTTTCTCCTGGGTCTGTAGGTCAGTGGTAATGTAGCTAAGCTAGGCTGGACTACAATC
TCAAGGTTAGGTTCAGGTCAGCTCTAAGCTGTGGGTTTGTGGGCTGACAGGAAGGTCTGCTTCAGGCTGTGGGCCCAAGGGTCAGCTGCA
GCACAGTGCCTCTGCTTCACGTGTCCTTTTCTGAGCCCCTGCTGAAAGACGTTATCCAGGACAAGCTCTTCTCATGCTGGTCACAGAAGA

>In-frame_ENST00000361311_ENST00000532692_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(amino acids)=121AA_start in transcript=2159_stop in transcript=2524
MWLSFSNVHSYRQPFSFQNLAATVESFMLAKHKSLISPFLSSLTPLLQAYRGKEISSPPGFQLFVPPIPLKAPASNTFPSQTEPSCLADC

--------------------------------------------------------------
>In-frame_ENST00000377288_ENST00000227135_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(transcript)=1330nt_BP=884nt
GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG
AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA
GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC
CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC
CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC
CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC
CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG
CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT
AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC
TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG
AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA
AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA
GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT
CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG

>In-frame_ENST00000377288_ENST00000227135_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(amino acids)=163AA_start in transcript=488_stop in transcript=0
MGSDARRARGGPWERAGPGGAGERSGGSARGGPGSGRAPPSPSAPPGARARGDAPGVGSERPGGARGTVSLSLAADGEPQLRVPTRAPGL

--------------------------------------------------------------
>In-frame_ENST00000377288_ENST00000532692_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(transcript)=4187nt_BP=884nt
GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG
AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA
GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC
CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC
CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC
CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC
CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG
CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT
AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC
TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG
AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA
AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA
GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT
CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG
TTTAATAAGCATACCATTGAAACATGCCACTTGAAGATTTCTCTGAGATCATGAGTTTGTTTACACTTGTCTCAAGCCTATCTATAGAGA
CCCTTGGATTTAGAATTATAGAACTAAAGTATCTGAGATTACAGAGATCTCAGAGGTTATGTGTTCTAACTATTATCAAATGAATAAATC
CTCTCTATCACATCCCCCAAAAATGTTCTTTAGCTCCTGTTTCACTCCTAGTGGTAAAGAATTTCACTGCTTTTTAAGGATAGTCTATTT
AATTTTGGAATTTTTAGAAAGATAAGCTGGGACAAAAATCTGCCTCCTTCAGCCTGGCCAACATGGTGAAACCCCATGTCTACTAAAAGT
ACAAAAATTGGCCAGGCGTGGTGCGCACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGTGGA
GGCTGCAGTAAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAACAAAACAAAACAAAAAAAAG
CCTCTGCCTCCTTGTAAGTTTAACCCACTGGTTTTCATTTATCATACATGTATTCAATCATTTATTGAAAATGTATTGAGTACTATTCAT
GTGCTGGGAATTAGTAGTGAATACTTGTTCTTACACTCATACAACTTACAATGCTTTATTGTTTTGCTCTCCAGAACCACACAGAACAAG
ACTAATAACATCATATTGTAAAAAGCAAAAGCTATCATATCATGCTGCCTTCTTCAGTTAAAACTTCCCAAGTTTTTAAATATACAATGG
TAATGCCTGTTTAACAAACTCAGAGGCTTTATCTCTTTTATGTTTTCAATGATTCATTCAAATCCCTAGTGCCTTAGTTTTAGAAAGTTC
CGTCTCTCCTTTTTGAGGCCTCTCCACCCTTGATTGTCCAAGAAACTGAGGGTTCATGTCTTAGACCAAAGGGTGCAGTTCTCTTCCCAA
TACAAAAGGTAGAAAGTGGAGTCTTACCATTTAGTTAATGCTGTTGCCTTCTACCATAATGTTGTAGCATAGTCCAGCAGACTGAGGTGA
TTCTCTGGCTGGTTCCAATTCCTGCCTGCACCATAGTGGATGGCCCATGATTTAGTTCCAGGATTACATCTCTCTTGGTTTATAGTCACA
AAGCCAGTGTTCCCCCAAAGCTTAAAAACAAGCCAGGATGGCTCAGTCCTGAGGAGATTCTAAAACCAGGTCTATGTTGTCACAACAAAT
ACTCTCCTACAAACACTTTGATCCTTGTCCTAGGCTTAGACATGCTCTTTCTGCAAAGCAGTTTTATTTCAGGTGCCTCACTGCCCTTCC
CTGGCACTGAGCCTTTATCAGGCTCTGCAACAGAGGTTCCCCCAAGTGATCGCCACTCAAACACAGTTGATTCACACCAACCCTTTCAAG
GTTGTGGCTTTCATTCTCTAATGTCCACTCATACAGGCAGCCTTTCTCCTTCCAAAATCTTGCTGCCACTGTAGAGAGTTTCATGCTAGC
TAAACACAAGTCTCTAATATCCCCCTTCCTCTCCTCCTTAACCCCTCTCCTCCAGGCTTACAGAGGAAAAGAAATCAGTTCTCCTCCAGG
ATTCCAGCTGTTCGTCCCTCCCATTCCACTGAAAGCACCAGCTTCTAACACCTTCCCCTCTCAGACAGAGCCATCCTGCTTAGCGGATTG
TCAAGGGGGGACCCAGAATTTATGCAAAGACTTAGATTCCCTGACCTGGAGAGATCAGAAGAGGAAAAAAGGGATTTTTTCCCTAGTGAG
TATATAGCAGGAAAAAAAAAAAAGATGAGTTAGCTTTTTCAGTAATTCTCCTGTTATACACATAAAGTGACTAGCACTATGCATTCCATA
CACACACACACACACACACAGATCTCATGGTAGTGATATTGGTAGTGAAGGAGGAAAAGGAAAAGGTGAGCAATGGATGTGATATTATGA
GAACAACACATATGAATGACACTTTATTAGAACTTATCTGGTTTTCCTCTTATCTCTCTGGCTGTTCCTTCTCAATTCCCTTCACTGGTA
ACTCTTCAACTCCCCAACCACTAAATGCTAAGTGCCCTTAGGCTCAGTCTTTCGACCCCATTTCTACACTCACTTGATTTCCTGCAGTTT
CATAGCTTTAAAATCCAATCTTCTTAATGATCACTCCCAGACCTTTCTCTCCTCTGCCTGCGAACTTCTATATTCAACTGCCTACATAAC
ATCCCCATTTGGATGTCTATAGGCATCTCAAAAGTAACATATAAAAAATGAATCCTGATATTGCCCCCAAATCTGAAACTTCCCCCACAC
CCAAGTTTTTCCATTCAAAAATGGCTGCTCCATTCTTCCATTTGCTCAGGCCAAAAACCTTGGATTCATCTTTAATGCGTCACTTTCTTT
CACACCCCATATACAATCTATCAGCAAAACCTGTGGGCTGTACCTATAAAATAATACTCAGAATCTGCCTACTTCTAACCACTTCCATTG
TTACCGCCTTGGTCCTAGTTCCCATGATAGCCTTGTGAATTATTGCAATAACCTATATTGGCCAGTGATTATCTCACTACTACTGCACAA
CCCATTCCAAAGTTAGTGGTTTAAGACAATTATATTTTCTCCTGGGTCTGTAGGTCAGTGGTAATGTAGCTAAGCTAGGCTGGACTACAA
TCTCAAGGTTAGGTTCAGGTCAGCTCTAAGCTGTGGGTTTGTGGGCTGACAGGAAGGTCTGCTTCAGGCTGTGGGCCCAAGGGTCAGCTG
CAGCACAGTGCCTCTGCTTCACGTGTCCTTTTCTGAGCCCCTGCTGAAAGACGTTATCCAGGACAAGCTCTTCTCATGCTGGTCACAGAA

>In-frame_ENST00000377288_ENST00000532692_TCGA-24-1550-01A_CLSTN1_chr1_9883701_-_SPA17_chr11_124561592_length(amino acids)=162AA_start in transcript=703_stop in transcript=215
MLRGAGSSGGPRRSRRRRRRDAGPRAQDAAPSPPQSSVLLKAAAATKMAAALSLGSGEGTRPGAGWRREGRGWGATRGARAADPGSARAR

--------------------------------------------------------------
>In-frame_ENST00000377298_ENST00000227135_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(transcript)=1330nt_BP=884nt
GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG
AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA
GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC
CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC
CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC
CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC
CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG
CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT
AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC
TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG
AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA
AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA
GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT
CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG

>In-frame_ENST00000377298_ENST00000227135_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(amino acids)=163AA_start in transcript=488_stop in transcript=0
MGSDARRARGGPWERAGPGGAGERSGGSARGGPGSGRAPPSPSAPPGARARGDAPGVGSERPGGARGTVSLSLAADGEPQLRVPTRAPGL

--------------------------------------------------------------
>In-frame_ENST00000377298_ENST00000532692_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(transcript)=4187nt_BP=884nt
GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG
AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA
GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC
CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC
CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC
CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC
CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG
CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT
AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC
TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG
AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA
AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA
GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT
CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG
TTTAATAAGCATACCATTGAAACATGCCACTTGAAGATTTCTCTGAGATCATGAGTTTGTTTACACTTGTCTCAAGCCTATCTATAGAGA
CCCTTGGATTTAGAATTATAGAACTAAAGTATCTGAGATTACAGAGATCTCAGAGGTTATGTGTTCTAACTATTATCAAATGAATAAATC
CTCTCTATCACATCCCCCAAAAATGTTCTTTAGCTCCTGTTTCACTCCTAGTGGTAAAGAATTTCACTGCTTTTTAAGGATAGTCTATTT
AATTTTGGAATTTTTAGAAAGATAAGCTGGGACAAAAATCTGCCTCCTTCAGCCTGGCCAACATGGTGAAACCCCATGTCTACTAAAAGT
ACAAAAATTGGCCAGGCGTGGTGCGCACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGTGGA
GGCTGCAGTAAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAACAAAACAAAACAAAAAAAAG
CCTCTGCCTCCTTGTAAGTTTAACCCACTGGTTTTCATTTATCATACATGTATTCAATCATTTATTGAAAATGTATTGAGTACTATTCAT
GTGCTGGGAATTAGTAGTGAATACTTGTTCTTACACTCATACAACTTACAATGCTTTATTGTTTTGCTCTCCAGAACCACACAGAACAAG
ACTAATAACATCATATTGTAAAAAGCAAAAGCTATCATATCATGCTGCCTTCTTCAGTTAAAACTTCCCAAGTTTTTAAATATACAATGG
TAATGCCTGTTTAACAAACTCAGAGGCTTTATCTCTTTTATGTTTTCAATGATTCATTCAAATCCCTAGTGCCTTAGTTTTAGAAAGTTC
CGTCTCTCCTTTTTGAGGCCTCTCCACCCTTGATTGTCCAAGAAACTGAGGGTTCATGTCTTAGACCAAAGGGTGCAGTTCTCTTCCCAA
TACAAAAGGTAGAAAGTGGAGTCTTACCATTTAGTTAATGCTGTTGCCTTCTACCATAATGTTGTAGCATAGTCCAGCAGACTGAGGTGA
TTCTCTGGCTGGTTCCAATTCCTGCCTGCACCATAGTGGATGGCCCATGATTTAGTTCCAGGATTACATCTCTCTTGGTTTATAGTCACA
AAGCCAGTGTTCCCCCAAAGCTTAAAAACAAGCCAGGATGGCTCAGTCCTGAGGAGATTCTAAAACCAGGTCTATGTTGTCACAACAAAT
ACTCTCCTACAAACACTTTGATCCTTGTCCTAGGCTTAGACATGCTCTTTCTGCAAAGCAGTTTTATTTCAGGTGCCTCACTGCCCTTCC
CTGGCACTGAGCCTTTATCAGGCTCTGCAACAGAGGTTCCCCCAAGTGATCGCCACTCAAACACAGTTGATTCACACCAACCCTTTCAAG
GTTGTGGCTTTCATTCTCTAATGTCCACTCATACAGGCAGCCTTTCTCCTTCCAAAATCTTGCTGCCACTGTAGAGAGTTTCATGCTAGC
TAAACACAAGTCTCTAATATCCCCCTTCCTCTCCTCCTTAACCCCTCTCCTCCAGGCTTACAGAGGAAAAGAAATCAGTTCTCCTCCAGG
ATTCCAGCTGTTCGTCCCTCCCATTCCACTGAAAGCACCAGCTTCTAACACCTTCCCCTCTCAGACAGAGCCATCCTGCTTAGCGGATTG
TCAAGGGGGGACCCAGAATTTATGCAAAGACTTAGATTCCCTGACCTGGAGAGATCAGAAGAGGAAAAAAGGGATTTTTTCCCTAGTGAG
TATATAGCAGGAAAAAAAAAAAAGATGAGTTAGCTTTTTCAGTAATTCTCCTGTTATACACATAAAGTGACTAGCACTATGCATTCCATA
CACACACACACACACACACAGATCTCATGGTAGTGATATTGGTAGTGAAGGAGGAAAAGGAAAAGGTGAGCAATGGATGTGATATTATGA
GAACAACACATATGAATGACACTTTATTAGAACTTATCTGGTTTTCCTCTTATCTCTCTGGCTGTTCCTTCTCAATTCCCTTCACTGGTA
ACTCTTCAACTCCCCAACCACTAAATGCTAAGTGCCCTTAGGCTCAGTCTTTCGACCCCATTTCTACACTCACTTGATTTCCTGCAGTTT
CATAGCTTTAAAATCCAATCTTCTTAATGATCACTCCCAGACCTTTCTCTCCTCTGCCTGCGAACTTCTATATTCAACTGCCTACATAAC
ATCCCCATTTGGATGTCTATAGGCATCTCAAAAGTAACATATAAAAAATGAATCCTGATATTGCCCCCAAATCTGAAACTTCCCCCACAC
CCAAGTTTTTCCATTCAAAAATGGCTGCTCCATTCTTCCATTTGCTCAGGCCAAAAACCTTGGATTCATCTTTAATGCGTCACTTTCTTT
CACACCCCATATACAATCTATCAGCAAAACCTGTGGGCTGTACCTATAAAATAATACTCAGAATCTGCCTACTTCTAACCACTTCCATTG
TTACCGCCTTGGTCCTAGTTCCCATGATAGCCTTGTGAATTATTGCAATAACCTATATTGGCCAGTGATTATCTCACTACTACTGCACAA
CCCATTCCAAAGTTAGTGGTTTAAGACAATTATATTTTCTCCTGGGTCTGTAGGTCAGTGGTAATGTAGCTAAGCTAGGCTGGACTACAA
TCTCAAGGTTAGGTTCAGGTCAGCTCTAAGCTGTGGGTTTGTGGGCTGACAGGAAGGTCTGCTTCAGGCTGTGGGCCCAAGGGTCAGCTG
CAGCACAGTGCCTCTGCTTCACGTGTCCTTTTCTGAGCCCCTGCTGAAAGACGTTATCCAGGACAAGCTCTTCTCATGCTGGTCACAGAA

>In-frame_ENST00000377298_ENST00000532692_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(amino acids)=162AA_start in transcript=703_stop in transcript=215
MLRGAGSSGGPRRSRRRRRRDAGPRAQDAAPSPPQSSVLLKAAAATKMAAALSLGSGEGTRPGAGWRREGRGWGATRGARAADPGSARAR

--------------------------------------------------------------
>In-frame_ENST00000361311_ENST00000227135_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(transcript)=788nt_BP=342nt
GAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCGCG
CGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCTAG
AGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGCTC
CCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTGAG
AAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATAAG
GAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATAGT
CTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTTCT
TATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTGTT

>In-frame_ENST00000361311_ENST00000227135_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(amino acids)=110AA_start in transcript=26_stop in transcript=358
MLPLPSARRCSEAGRAPRPERAAQRHGGGGGGSSLDPRSSPRRGAASPRPLEPRELRELRSASRAPPCRSRPGLAMLRRPAPALAPAARL

--------------------------------------------------------------
>In-frame_ENST00000361311_ENST00000532692_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(transcript)=3645nt_BP=342nt
GAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCGCG
CGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCTAG
AGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGCTC
CCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTGAG
AAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATAAG
GAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATAGT
CTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTTCT
TATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTGTT
TAATAAGCATACCATTGAAACATGCCACTTGAAGATTTCTCTGAGATCATGAGTTTGTTTACACTTGTCTCAAGCCTATCTATAGAGACC
CTTGGATTTAGAATTATAGAACTAAAGTATCTGAGATTACAGAGATCTCAGAGGTTATGTGTTCTAACTATTATCAAATGAATAAATCCT
CTCTATCACATCCCCCAAAAATGTTCTTTAGCTCCTGTTTCACTCCTAGTGGTAAAGAATTTCACTGCTTTTTAAGGATAGTCTATTTAA
TTTTGGAATTTTTAGAAAGATAAGCTGGGACAAAAATCTGCCTCCTTCAGCCTGGCCAACATGGTGAAACCCCATGTCTACTAAAAGTAC
AAAAATTGGCCAGGCGTGGTGCGCACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGTGGAGG
CTGCAGTAAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAACAAAACAAAACAAAAAAAAGCC
TCTGCCTCCTTGTAAGTTTAACCCACTGGTTTTCATTTATCATACATGTATTCAATCATTTATTGAAAATGTATTGAGTACTATTCATGT
GCTGGGAATTAGTAGTGAATACTTGTTCTTACACTCATACAACTTACAATGCTTTATTGTTTTGCTCTCCAGAACCACACAGAACAAGAC
TAATAACATCATATTGTAAAAAGCAAAAGCTATCATATCATGCTGCCTTCTTCAGTTAAAACTTCCCAAGTTTTTAAATATACAATGGTA
ATGCCTGTTTAACAAACTCAGAGGCTTTATCTCTTTTATGTTTTCAATGATTCATTCAAATCCCTAGTGCCTTAGTTTTAGAAAGTTCCG
TCTCTCCTTTTTGAGGCCTCTCCACCCTTGATTGTCCAAGAAACTGAGGGTTCATGTCTTAGACCAAAGGGTGCAGTTCTCTTCCCAATA
CAAAAGGTAGAAAGTGGAGTCTTACCATTTAGTTAATGCTGTTGCCTTCTACCATAATGTTGTAGCATAGTCCAGCAGACTGAGGTGATT
CTCTGGCTGGTTCCAATTCCTGCCTGCACCATAGTGGATGGCCCATGATTTAGTTCCAGGATTACATCTCTCTTGGTTTATAGTCACAAA
GCCAGTGTTCCCCCAAAGCTTAAAAACAAGCCAGGATGGCTCAGTCCTGAGGAGATTCTAAAACCAGGTCTATGTTGTCACAACAAATAC
TCTCCTACAAACACTTTGATCCTTGTCCTAGGCTTAGACATGCTCTTTCTGCAAAGCAGTTTTATTTCAGGTGCCTCACTGCCCTTCCCT
GGCACTGAGCCTTTATCAGGCTCTGCAACAGAGGTTCCCCCAAGTGATCGCCACTCAAACACAGTTGATTCACACCAACCCTTTCAAGGT
TGTGGCTTTCATTCTCTAATGTCCACTCATACAGGCAGCCTTTCTCCTTCCAAAATCTTGCTGCCACTGTAGAGAGTTTCATGCTAGCTA
AACACAAGTCTCTAATATCCCCCTTCCTCTCCTCCTTAACCCCTCTCCTCCAGGCTTACAGAGGAAAAGAAATCAGTTCTCCTCCAGGAT
TCCAGCTGTTCGTCCCTCCCATTCCACTGAAAGCACCAGCTTCTAACACCTTCCCCTCTCAGACAGAGCCATCCTGCTTAGCGGATTGTC
AAGGGGGGACCCAGAATTTATGCAAAGACTTAGATTCCCTGACCTGGAGAGATCAGAAGAGGAAAAAAGGGATTTTTTCCCTAGTGAGTA
TATAGCAGGAAAAAAAAAAAAGATGAGTTAGCTTTTTCAGTAATTCTCCTGTTATACACATAAAGTGACTAGCACTATGCATTCCATACA
CACACACACACACACACAGATCTCATGGTAGTGATATTGGTAGTGAAGGAGGAAAAGGAAAAGGTGAGCAATGGATGTGATATTATGAGA
ACAACACATATGAATGACACTTTATTAGAACTTATCTGGTTTTCCTCTTATCTCTCTGGCTGTTCCTTCTCAATTCCCTTCACTGGTAAC
TCTTCAACTCCCCAACCACTAAATGCTAAGTGCCCTTAGGCTCAGTCTTTCGACCCCATTTCTACACTCACTTGATTTCCTGCAGTTTCA
TAGCTTTAAAATCCAATCTTCTTAATGATCACTCCCAGACCTTTCTCTCCTCTGCCTGCGAACTTCTATATTCAACTGCCTACATAACAT
CCCCATTTGGATGTCTATAGGCATCTCAAAAGTAACATATAAAAAATGAATCCTGATATTGCCCCCAAATCTGAAACTTCCCCCACACCC
AAGTTTTTCCATTCAAAAATGGCTGCTCCATTCTTCCATTTGCTCAGGCCAAAAACCTTGGATTCATCTTTAATGCGTCACTTTCTTTCA
CACCCCATATACAATCTATCAGCAAAACCTGTGGGCTGTACCTATAAAATAATACTCAGAATCTGCCTACTTCTAACCACTTCCATTGTT
ACCGCCTTGGTCCTAGTTCCCATGATAGCCTTGTGAATTATTGCAATAACCTATATTGGCCAGTGATTATCTCACTACTACTGCACAACC
CATTCCAAAGTTAGTGGTTTAAGACAATTATATTTTCTCCTGGGTCTGTAGGTCAGTGGTAATGTAGCTAAGCTAGGCTGGACTACAATC
TCAAGGTTAGGTTCAGGTCAGCTCTAAGCTGTGGGTTTGTGGGCTGACAGGAAGGTCTGCTTCAGGCTGTGGGCCCAAGGGTCAGCTGCA
GCACAGTGCCTCTGCTTCACGTGTCCTTTTCTGAGCCCCTGCTGAAAGACGTTATCCAGGACAAGCTCTTCTCATGCTGGTCACAGAAGA

>In-frame_ENST00000361311_ENST00000532692_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(amino acids)=121AA_start in transcript=2159_stop in transcript=2524
MWLSFSNVHSYRQPFSFQNLAATVESFMLAKHKSLISPFLSSLTPLLQAYRGKEISSPPGFQLFVPPIPLKAPASNTFPSQTEPSCLADC

--------------------------------------------------------------
>In-frame_ENST00000377288_ENST00000227135_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(transcript)=1330nt_BP=884nt
GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG
AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA
GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC
CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC
CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC
CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC
CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG
CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT
AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC
TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG
AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA
AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA
GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT
CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG

>In-frame_ENST00000377288_ENST00000227135_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(amino acids)=163AA_start in transcript=488_stop in transcript=0
MGSDARRARGGPWERAGPGGAGERSGGSARGGPGSGRAPPSPSAPPGARARGDAPGVGSERPGGARGTVSLSLAADGEPQLRVPTRAPGL

--------------------------------------------------------------
>In-frame_ENST00000377288_ENST00000532692_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(transcript)=4187nt_BP=884nt
GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG
AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA
GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC
CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC
CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC
CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC
CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG
CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT
AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC
TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG
AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA
AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA
GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT
CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG
TTTAATAAGCATACCATTGAAACATGCCACTTGAAGATTTCTCTGAGATCATGAGTTTGTTTACACTTGTCTCAAGCCTATCTATAGAGA
CCCTTGGATTTAGAATTATAGAACTAAAGTATCTGAGATTACAGAGATCTCAGAGGTTATGTGTTCTAACTATTATCAAATGAATAAATC
CTCTCTATCACATCCCCCAAAAATGTTCTTTAGCTCCTGTTTCACTCCTAGTGGTAAAGAATTTCACTGCTTTTTAAGGATAGTCTATTT
AATTTTGGAATTTTTAGAAAGATAAGCTGGGACAAAAATCTGCCTCCTTCAGCCTGGCCAACATGGTGAAACCCCATGTCTACTAAAAGT
ACAAAAATTGGCCAGGCGTGGTGCGCACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGTGGA
GGCTGCAGTAAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAACAAAACAAAACAAAAAAAAG
CCTCTGCCTCCTTGTAAGTTTAACCCACTGGTTTTCATTTATCATACATGTATTCAATCATTTATTGAAAATGTATTGAGTACTATTCAT
GTGCTGGGAATTAGTAGTGAATACTTGTTCTTACACTCATACAACTTACAATGCTTTATTGTTTTGCTCTCCAGAACCACACAGAACAAG
ACTAATAACATCATATTGTAAAAAGCAAAAGCTATCATATCATGCTGCCTTCTTCAGTTAAAACTTCCCAAGTTTTTAAATATACAATGG
TAATGCCTGTTTAACAAACTCAGAGGCTTTATCTCTTTTATGTTTTCAATGATTCATTCAAATCCCTAGTGCCTTAGTTTTAGAAAGTTC
CGTCTCTCCTTTTTGAGGCCTCTCCACCCTTGATTGTCCAAGAAACTGAGGGTTCATGTCTTAGACCAAAGGGTGCAGTTCTCTTCCCAA
TACAAAAGGTAGAAAGTGGAGTCTTACCATTTAGTTAATGCTGTTGCCTTCTACCATAATGTTGTAGCATAGTCCAGCAGACTGAGGTGA
TTCTCTGGCTGGTTCCAATTCCTGCCTGCACCATAGTGGATGGCCCATGATTTAGTTCCAGGATTACATCTCTCTTGGTTTATAGTCACA
AAGCCAGTGTTCCCCCAAAGCTTAAAAACAAGCCAGGATGGCTCAGTCCTGAGGAGATTCTAAAACCAGGTCTATGTTGTCACAACAAAT
ACTCTCCTACAAACACTTTGATCCTTGTCCTAGGCTTAGACATGCTCTTTCTGCAAAGCAGTTTTATTTCAGGTGCCTCACTGCCCTTCC
CTGGCACTGAGCCTTTATCAGGCTCTGCAACAGAGGTTCCCCCAAGTGATCGCCACTCAAACACAGTTGATTCACACCAACCCTTTCAAG
GTTGTGGCTTTCATTCTCTAATGTCCACTCATACAGGCAGCCTTTCTCCTTCCAAAATCTTGCTGCCACTGTAGAGAGTTTCATGCTAGC
TAAACACAAGTCTCTAATATCCCCCTTCCTCTCCTCCTTAACCCCTCTCCTCCAGGCTTACAGAGGAAAAGAAATCAGTTCTCCTCCAGG
ATTCCAGCTGTTCGTCCCTCCCATTCCACTGAAAGCACCAGCTTCTAACACCTTCCCCTCTCAGACAGAGCCATCCTGCTTAGCGGATTG
TCAAGGGGGGACCCAGAATTTATGCAAAGACTTAGATTCCCTGACCTGGAGAGATCAGAAGAGGAAAAAAGGGATTTTTTCCCTAGTGAG
TATATAGCAGGAAAAAAAAAAAAGATGAGTTAGCTTTTTCAGTAATTCTCCTGTTATACACATAAAGTGACTAGCACTATGCATTCCATA
CACACACACACACACACACAGATCTCATGGTAGTGATATTGGTAGTGAAGGAGGAAAAGGAAAAGGTGAGCAATGGATGTGATATTATGA
GAACAACACATATGAATGACACTTTATTAGAACTTATCTGGTTTTCCTCTTATCTCTCTGGCTGTTCCTTCTCAATTCCCTTCACTGGTA
ACTCTTCAACTCCCCAACCACTAAATGCTAAGTGCCCTTAGGCTCAGTCTTTCGACCCCATTTCTACACTCACTTGATTTCCTGCAGTTT
CATAGCTTTAAAATCCAATCTTCTTAATGATCACTCCCAGACCTTTCTCTCCTCTGCCTGCGAACTTCTATATTCAACTGCCTACATAAC
ATCCCCATTTGGATGTCTATAGGCATCTCAAAAGTAACATATAAAAAATGAATCCTGATATTGCCCCCAAATCTGAAACTTCCCCCACAC
CCAAGTTTTTCCATTCAAAAATGGCTGCTCCATTCTTCCATTTGCTCAGGCCAAAAACCTTGGATTCATCTTTAATGCGTCACTTTCTTT
CACACCCCATATACAATCTATCAGCAAAACCTGTGGGCTGTACCTATAAAATAATACTCAGAATCTGCCTACTTCTAACCACTTCCATTG
TTACCGCCTTGGTCCTAGTTCCCATGATAGCCTTGTGAATTATTGCAATAACCTATATTGGCCAGTGATTATCTCACTACTACTGCACAA
CCCATTCCAAAGTTAGTGGTTTAAGACAATTATATTTTCTCCTGGGTCTGTAGGTCAGTGGTAATGTAGCTAAGCTAGGCTGGACTACAA
TCTCAAGGTTAGGTTCAGGTCAGCTCTAAGCTGTGGGTTTGTGGGCTGACAGGAAGGTCTGCTTCAGGCTGTGGGCCCAAGGGTCAGCTG
CAGCACAGTGCCTCTGCTTCACGTGTCCTTTTCTGAGCCCCTGCTGAAAGACGTTATCCAGGACAAGCTCTTCTCATGCTGGTCACAGAA

>In-frame_ENST00000377288_ENST00000532692_TCGA-24-1550_CLSTN1_chr1_9883700_-_SPA17_chr11_124561591_length(amino acids)=162AA_start in transcript=703_stop in transcript=215
MLRGAGSSGGPRRSRRRRRRDAGPRAQDAAPSPPQSSVLLKAAAATKMAAALSLGSGEGTRPGAGWRREGRGWGATRGARAADPGSARAR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CLSTN1-SPA17


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CLSTN1-SPA17


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CLSTN1-SPA17


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource