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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CNNM2-RBP4 (FusionGDB2 ID:17710)

Fusion Gene Summary for CNNM2-RBP4

check button Fusion gene summary
Fusion gene informationFusion gene name: CNNM2-RBP4
Fusion gene ID: 17710
HgeneTgene
Gene symbol

CNNM2

RBP4

Gene ID

54805

5950

Gene namecyclin and CBS domain divalent metal cation transport mediator 2retinol binding protein 4
SynonymsACDP2|HOMG6|HOMGSMRMCOPCB10|RDCCAS
Cytomap

10q24.32

10q23.33

Type of geneprotein-codingprotein-coding
Descriptionmetal transporter CNNM2ancient conserved domain-containing protein 2cyclin M2retinol-binding protein 4PRBPRBPplasma retinol-binding proteinretinol binding protein 4, plasmaretinol-binding protein 4, interstitial
Modification date2020031320200313
UniProtAcc

Q9H8M5

.
Ensembl transtripts involved in fusion geneENST00000369878, ENST00000433628, 
ENST00000369875, ENST00000475511, 
ENST00000371464, ENST00000371467, 
ENST00000371469, 
Fusion gene scores* DoF score5 X 2 X 3=308 X 5 X 4=160
# samples 58
** MAII scorelog2(5/30*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(8/160*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CNNM2 [Title/Abstract] AND RBP4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCNNM2(104679858)-RBP4(95353792), # samples:4
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRBP4

GO:0030277

maintenance of gastrointestinal epithelium

10944490

TgeneRBP4

GO:0032526

response to retinoic acid

571335

TgeneRBP4

GO:0042593

glucose homeostasis

17003346


check buttonFusion gene breakpoints across CNNM2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across RBP4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-30-1714-01ACNNM2chr10

104679858

+RBP4chr10

95353792

-
ChimerDB4OVTCGA-30-1714CNNM2chr10

104679858

+RBP4chr10

95353792

-
ChimerDB4UCECTCGA-A5-A1OJCNNM2chr10

104679858

+RBP4chr10

95353792

-
ChimerDB4OVTCGA-30-1714-01ACNNM2chr10

104679858

+RBP4chr10

95353792

-


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Fusion Gene ORF analysis for CNNM2-RBP4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000369878ENST00000371464CNNM2chr10

104679858

+RBP4chr10

95353792

-
In-frameENST00000369878ENST00000371467CNNM2chr10

104679858

+RBP4chr10

95353792

-
In-frameENST00000369878ENST00000371469CNNM2chr10

104679858

+RBP4chr10

95353792

-
In-frameENST00000433628ENST00000371464CNNM2chr10

104679858

+RBP4chr10

95353792

-
In-frameENST00000433628ENST00000371467CNNM2chr10

104679858

+RBP4chr10

95353792

-
In-frameENST00000433628ENST00000371469CNNM2chr10

104679858

+RBP4chr10

95353792

-
In-frameENST00000369875ENST00000371464CNNM2chr10

104679858

+RBP4chr10

95353792

-
In-frameENST00000369875ENST00000371467CNNM2chr10

104679858

+RBP4chr10

95353792

-
In-frameENST00000369875ENST00000371469CNNM2chr10

104679858

+RBP4chr10

95353792

-
intron-3CDSENST00000475511ENST00000371464CNNM2chr10

104679858

+RBP4chr10

95353792

-
intron-3CDSENST00000475511ENST00000371467CNNM2chr10

104679858

+RBP4chr10

95353792

-
intron-3CDSENST00000475511ENST00000371469CNNM2chr10

104679858

+RBP4chr10

95353792

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000369878CNNM2chr10104679858+ENST00000371464RBP4chr1095353792-244818091882059623
ENST00000369878CNNM2chr10104679858+ENST00000371467RBP4chr1095353792-244818091882059623
ENST00000369878CNNM2chr10104679858+ENST00000371469RBP4chr1095353792-224618091882059623
ENST00000433628CNNM2chr10104679858+ENST00000371464RBP4chr1095353792-238417451241995623
ENST00000433628CNNM2chr10104679858+ENST00000371467RBP4chr1095353792-238417451241995623
ENST00000433628CNNM2chr10104679858+ENST00000371469RBP4chr1095353792-218217451241995623
ENST00000369875CNNM2chr10104679858+ENST00000371464RBP4chr1095353792-242417851642035623
ENST00000369875CNNM2chr10104679858+ENST00000371467RBP4chr1095353792-242417851642035623
ENST00000369875CNNM2chr10104679858+ENST00000371469RBP4chr1095353792-222217851642035623

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000369878ENST00000371464CNNM2chr10104679858+RBP4chr1095353792-0.0203620940.9796379
ENST00000369878ENST00000371467CNNM2chr10104679858+RBP4chr1095353792-0.0203620940.9796379
ENST00000369878ENST00000371469CNNM2chr10104679858+RBP4chr1095353792-0.0234433710.97655666
ENST00000433628ENST00000371464CNNM2chr10104679858+RBP4chr1095353792-0.0200404130.9799596
ENST00000433628ENST00000371467CNNM2chr10104679858+RBP4chr1095353792-0.0200404130.9799596
ENST00000433628ENST00000371469CNNM2chr10104679858+RBP4chr1095353792-0.0222433230.97775674
ENST00000369875ENST00000371464CNNM2chr10104679858+RBP4chr1095353792-0.020297590.9797024
ENST00000369875ENST00000371467CNNM2chr10104679858+RBP4chr1095353792-0.020297590.9797024
ENST00000369875ENST00000371469CNNM2chr10104679858+RBP4chr1095353792-0.0229703170.9770297

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Fusion Genomic Features for CNNM2-RBP4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CNNM2-RBP4


check button Go to

FGviewer for the breakpoints of chr10:104679858-chr10:95353792

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CNNM2

Q9H8M5

.
FUNCTION: Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). {ECO:0000250|UniProtKB:Q3TWN3}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+12251_431540.3333333333334553.0DomainCNNM transmembrane
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+12450_511540.3333333333334553.0DomainCBS 1
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+18251_431540.3333333333334876.0DomainCNNM transmembrane
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+18450_511540.3333333333334876.0DomainCBS 1
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+17251_431540.3333333333334854.0DomainCNNM transmembrane
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+17450_511540.3333333333334854.0DomainCBS 1
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+12314_334540.3333333333334553.0IntramembraneHelical
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+18314_334540.3333333333334876.0IntramembraneHelical
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+17314_334540.3333333333334854.0IntramembraneHelical
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+121_250540.3333333333334553.0Topological domainExtracellular
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+12272_313540.3333333333334553.0Topological domainCytoplasmic
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+12335_338540.3333333333334553.0Topological domainCytoplasmic
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+12360_368540.3333333333334553.0Topological domainExtracellular
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+181_250540.3333333333334876.0Topological domainExtracellular
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+18272_313540.3333333333334876.0Topological domainCytoplasmic
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+18335_338540.3333333333334876.0Topological domainCytoplasmic
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+18360_368540.3333333333334876.0Topological domainExtracellular
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+171_250540.3333333333334854.0Topological domainExtracellular
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+17272_313540.3333333333334854.0Topological domainCytoplasmic
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+17335_338540.3333333333334854.0Topological domainCytoplasmic
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+17360_368540.3333333333334854.0Topological domainExtracellular
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+12251_271540.3333333333334553.0TransmembraneHelical
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+12339_359540.3333333333334553.0TransmembraneHelical
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+12369_389540.3333333333334553.0TransmembraneHelical
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+18251_271540.3333333333334876.0TransmembraneHelical
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+18339_359540.3333333333334876.0TransmembraneHelical
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+18369_389540.3333333333334876.0TransmembraneHelical
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+17251_271540.3333333333334854.0TransmembraneHelical
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+17339_359540.3333333333334854.0TransmembraneHelical
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+17369_389540.3333333333334854.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+12518_584540.3333333333334553.0DomainCBS 2
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+18518_584540.3333333333334876.0DomainCBS 2
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+17518_584540.3333333333334854.0DomainCBS 2
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369875+12390_875540.3333333333334553.0Topological domainCytoplasmic
HgeneCNNM2chr10:104679858chr10:95353792ENST00000369878+18390_875540.3333333333334876.0Topological domainCytoplasmic
HgeneCNNM2chr10:104679858chr10:95353792ENST00000433628+17390_875540.3333333333334854.0Topological domainCytoplasmic


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Fusion Gene Sequence for CNNM2-RBP4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000369878_ENST00000371464_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(transcript)=2448nt_BP=1809nt
TCCCTCCCTCTTTCCCTCCCGCGAGCCTCGGGGTTCCTCAGCTGGCTGAGGTGGAGTCAGTGTCAGTCAGGGAGGCGAACTGCTGAGCAC
TGGCCGCGGACGCTCCGTTGCAGTCTCGCCCAGGGGCCGGTACCTGCGCTCGCGCCGCCGGGTTGAAAGGATGAAGCCGCAGCTGGAGCA
GCCACCCTATGATTGGCTGTGGCGCTTGTGAACCCAAAGTAAAGATGGCGGGCGGGCAGGCAGCCGCCGCACTGCCCACTTGGAAGATGG
CGGCGCGCCGCAGCCTCAGCGCTCGCGGCCGGGGGATCCTGCAGGCGGCTGCGGGGCGGCTGCTGCCGCTGCTCCTGCTGAGCTGCTGCT
GCGGTGCGGGCGGCTGCGCAGCGGTGGGCGAGAATGAGGAGACGGTGATCATCGGGCTGCGACTGGAGGACACGAACGACGTGTCGTTCA
TGGAAGGGGGGGCGCTGCGGGTGAGCGAACGGACCCGGGTCAAGCTGCGGGTGTACGGGCAGAACATCAATAACGAGACGTGGTCCCGCA
TCGCCTTCACCGAGCACGAGCGGCGGCGCCACAGCCCGGGGGAGCGCGGGCTGGGGGGCCCCGCGCCGCCAGAGCCGGACAGCGGCCCCC
AGCGATGCGGCATCCGCACCTCAGACATCATCATCTTGCCCCACATCATTCTCAACCGCCGCACCTCGGGCATCATCGAGATCGAGATCA
AACCGCTACGCAAGATGGAGAAGAGCAAGTCCTATTACCTGTGCACGTCGCTCTCCACGCCCGCCCTGGGCGCCGGCGGCTCGGGGTCCA
CGGGTGGCGCCGTCGGGGGCAAGGGTGGCTCGGGGGTGGCCGGGCTCCCGCCGCCCCCGTGGGCCGAGACCACCTGGATTTACCACGACG
GCGAGGACACCAAGATGATCGTAGGCGAAGAGAAGAAGTTCCTGCTGCCCTTCTGGCTGCAGGTGATCTTCATTTCGCTGCTGCTGTGCC
TGTCGGGCATGTTCAGCGGCCTCAACCTGGGGCTCATGGCCCTGGACCCGATGGAGCTGCGCATCGTGCAGAACTGCGGCACGGAGAAGG
AGAAGAATTACGCCAAGCGCATCGAGCCGGTGCGCAGGCAGGGCAACTACCTGCTGTGCTCACTGCTGCTGGGCAACGTGCTGGTCAACA
CCACGCTCACCATCCTGCTCGACGACATCGCCGGCTCGGGCCTCGTGGCCGTGGTAGTCTCCACCATCGGTATCGTCATCTTCGGAGAGA
TCGTGCCCCAGGCCATCTGCTCCCGGCATGGCCTGGCTGTGGGGGCCAACACCATCTTCCTCACCAAGTTTTTCATGATGATGACCTTCC
CCGCTTCCTACCCGGTCAGCAAGCTGCTGGACTGCGTCCTGGGCCAGGAGATAGGCACCGTCTATAACCGGGAAAAACTGCTGGAGATGC
TCCGGGTCACCGATCCCTACAACGACCTCGTTAAGGAGGAGCTGAACATCATCCAAGGGGCGCTGGAGCTCCGCACCAAGACGGTGGAGG
ACGTGATGACCCCACTCCGGGACTGCTTCATGATCACCGGCGAAGCCATCCTGGACTTCAACACCATGTCTGAGATCATGGAGAGCGGCT
ACACCCGCATTCCAGTGTTTGAAGGGGAGCGCTCCAATATCGTGGACCTGCTGTTTGTCAAAGACTTGGCCTTCGTGGATCCCGATGACT
GTACCCCCCTGAAAACCATCACCAAATTTTATAACCACCCCTTGCACTTTGTTTTCAATGACACCAAGTTGGACGCTATGCTGGAAGAAT
TTAAGAAAGATGATGACCACTGGATCGTCGACACAGACTACGACACGTATGCCGTGCAGTACTCCTGCCGCCTCCTGAACCTCGATGGCA
CCTGTGCTGACAGCTACTCCTTCGTGTTTTCCCGGGACCCCAACGGCCTGCCCCCAGAAGCGCAGAAGATTGTAAGGCAGCGGCAGGAGG
AGCTGTGCCTGGCCAGGCAGTACAGGCTGATCGTCCACAACGGTTACTGCGATGGCAGATCAGAAAGAAACCTTTTGTAGCAATATCAAG
AATCTAGTTTCATCTGAGAACTTCTGATTAGCTCTCAGTCTTCAGCTCTATTTATCTTAGGAGTTTAATTTGCCCTTCTCTCCCCATCTT
CCCTCAGTTCCCATAAAACCTTCATTACACATAAAGATACACGTGGGGGTCAGTGAATCTGCTTGCCTTTCCTGAAAGTTTCTGGGGCTT
AAGATTCCAGACTCTGATTCATTAAACTATAGTCACCCGTGTCCTGTGATTTTAGTTTTCATTTGTGTTTATGTCTGTGCTGCAGACGGA
TGGGTGGGGTGCGCTTCTTTATACCAGGAGCACGTGGCTCTTTCTGACCTTTGGCCTGTTCTAGTGCCTAATCTCCATTATTAAATACTG

>In-frame_ENST00000369878_ENST00000371464_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(amino acids)=623AA_start in transcript=188_stop in transcript=2059
MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEG
GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPL
RKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSG
MFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVP
QAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVM
TPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK

--------------------------------------------------------------
>In-frame_ENST00000369878_ENST00000371467_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(transcript)=2448nt_BP=1809nt
TCCCTCCCTCTTTCCCTCCCGCGAGCCTCGGGGTTCCTCAGCTGGCTGAGGTGGAGTCAGTGTCAGTCAGGGAGGCGAACTGCTGAGCAC
TGGCCGCGGACGCTCCGTTGCAGTCTCGCCCAGGGGCCGGTACCTGCGCTCGCGCCGCCGGGTTGAAAGGATGAAGCCGCAGCTGGAGCA
GCCACCCTATGATTGGCTGTGGCGCTTGTGAACCCAAAGTAAAGATGGCGGGCGGGCAGGCAGCCGCCGCACTGCCCACTTGGAAGATGG
CGGCGCGCCGCAGCCTCAGCGCTCGCGGCCGGGGGATCCTGCAGGCGGCTGCGGGGCGGCTGCTGCCGCTGCTCCTGCTGAGCTGCTGCT
GCGGTGCGGGCGGCTGCGCAGCGGTGGGCGAGAATGAGGAGACGGTGATCATCGGGCTGCGACTGGAGGACACGAACGACGTGTCGTTCA
TGGAAGGGGGGGCGCTGCGGGTGAGCGAACGGACCCGGGTCAAGCTGCGGGTGTACGGGCAGAACATCAATAACGAGACGTGGTCCCGCA
TCGCCTTCACCGAGCACGAGCGGCGGCGCCACAGCCCGGGGGAGCGCGGGCTGGGGGGCCCCGCGCCGCCAGAGCCGGACAGCGGCCCCC
AGCGATGCGGCATCCGCACCTCAGACATCATCATCTTGCCCCACATCATTCTCAACCGCCGCACCTCGGGCATCATCGAGATCGAGATCA
AACCGCTACGCAAGATGGAGAAGAGCAAGTCCTATTACCTGTGCACGTCGCTCTCCACGCCCGCCCTGGGCGCCGGCGGCTCGGGGTCCA
CGGGTGGCGCCGTCGGGGGCAAGGGTGGCTCGGGGGTGGCCGGGCTCCCGCCGCCCCCGTGGGCCGAGACCACCTGGATTTACCACGACG
GCGAGGACACCAAGATGATCGTAGGCGAAGAGAAGAAGTTCCTGCTGCCCTTCTGGCTGCAGGTGATCTTCATTTCGCTGCTGCTGTGCC
TGTCGGGCATGTTCAGCGGCCTCAACCTGGGGCTCATGGCCCTGGACCCGATGGAGCTGCGCATCGTGCAGAACTGCGGCACGGAGAAGG
AGAAGAATTACGCCAAGCGCATCGAGCCGGTGCGCAGGCAGGGCAACTACCTGCTGTGCTCACTGCTGCTGGGCAACGTGCTGGTCAACA
CCACGCTCACCATCCTGCTCGACGACATCGCCGGCTCGGGCCTCGTGGCCGTGGTAGTCTCCACCATCGGTATCGTCATCTTCGGAGAGA
TCGTGCCCCAGGCCATCTGCTCCCGGCATGGCCTGGCTGTGGGGGCCAACACCATCTTCCTCACCAAGTTTTTCATGATGATGACCTTCC
CCGCTTCCTACCCGGTCAGCAAGCTGCTGGACTGCGTCCTGGGCCAGGAGATAGGCACCGTCTATAACCGGGAAAAACTGCTGGAGATGC
TCCGGGTCACCGATCCCTACAACGACCTCGTTAAGGAGGAGCTGAACATCATCCAAGGGGCGCTGGAGCTCCGCACCAAGACGGTGGAGG
ACGTGATGACCCCACTCCGGGACTGCTTCATGATCACCGGCGAAGCCATCCTGGACTTCAACACCATGTCTGAGATCATGGAGAGCGGCT
ACACCCGCATTCCAGTGTTTGAAGGGGAGCGCTCCAATATCGTGGACCTGCTGTTTGTCAAAGACTTGGCCTTCGTGGATCCCGATGACT
GTACCCCCCTGAAAACCATCACCAAATTTTATAACCACCCCTTGCACTTTGTTTTCAATGACACCAAGTTGGACGCTATGCTGGAAGAAT
TTAAGAAAGATGATGACCACTGGATCGTCGACACAGACTACGACACGTATGCCGTGCAGTACTCCTGCCGCCTCCTGAACCTCGATGGCA
CCTGTGCTGACAGCTACTCCTTCGTGTTTTCCCGGGACCCCAACGGCCTGCCCCCAGAAGCGCAGAAGATTGTAAGGCAGCGGCAGGAGG
AGCTGTGCCTGGCCAGGCAGTACAGGCTGATCGTCCACAACGGTTACTGCGATGGCAGATCAGAAAGAAACCTTTTGTAGCAATATCAAG
AATCTAGTTTCATCTGAGAACTTCTGATTAGCTCTCAGTCTTCAGCTCTATTTATCTTAGGAGTTTAATTTGCCCTTCTCTCCCCATCTT
CCCTCAGTTCCCATAAAACCTTCATTACACATAAAGATACACGTGGGGGTCAGTGAATCTGCTTGCCTTTCCTGAAAGTTTCTGGGGCTT
AAGATTCCAGACTCTGATTCATTAAACTATAGTCACCCGTGTCCTGTGATTTTAGTTTTCATTTGTGTTTATGTCTGTGCTGCAGACGGA
TGGGTGGGGTGCGCTTCTTTATACCAGGAGCACGTGGCTCTTTCTGACCTTTGGCCTGTTCTAGTGCCTAATCTCCATTATTAAATACTG

>In-frame_ENST00000369878_ENST00000371467_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(amino acids)=623AA_start in transcript=188_stop in transcript=2059
MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEG
GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPL
RKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSG
MFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVP
QAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVM
TPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK

--------------------------------------------------------------
>In-frame_ENST00000369878_ENST00000371469_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(transcript)=2246nt_BP=1809nt
TCCCTCCCTCTTTCCCTCCCGCGAGCCTCGGGGTTCCTCAGCTGGCTGAGGTGGAGTCAGTGTCAGTCAGGGAGGCGAACTGCTGAGCAC
TGGCCGCGGACGCTCCGTTGCAGTCTCGCCCAGGGGCCGGTACCTGCGCTCGCGCCGCCGGGTTGAAAGGATGAAGCCGCAGCTGGAGCA
GCCACCCTATGATTGGCTGTGGCGCTTGTGAACCCAAAGTAAAGATGGCGGGCGGGCAGGCAGCCGCCGCACTGCCCACTTGGAAGATGG
CGGCGCGCCGCAGCCTCAGCGCTCGCGGCCGGGGGATCCTGCAGGCGGCTGCGGGGCGGCTGCTGCCGCTGCTCCTGCTGAGCTGCTGCT
GCGGTGCGGGCGGCTGCGCAGCGGTGGGCGAGAATGAGGAGACGGTGATCATCGGGCTGCGACTGGAGGACACGAACGACGTGTCGTTCA
TGGAAGGGGGGGCGCTGCGGGTGAGCGAACGGACCCGGGTCAAGCTGCGGGTGTACGGGCAGAACATCAATAACGAGACGTGGTCCCGCA
TCGCCTTCACCGAGCACGAGCGGCGGCGCCACAGCCCGGGGGAGCGCGGGCTGGGGGGCCCCGCGCCGCCAGAGCCGGACAGCGGCCCCC
AGCGATGCGGCATCCGCACCTCAGACATCATCATCTTGCCCCACATCATTCTCAACCGCCGCACCTCGGGCATCATCGAGATCGAGATCA
AACCGCTACGCAAGATGGAGAAGAGCAAGTCCTATTACCTGTGCACGTCGCTCTCCACGCCCGCCCTGGGCGCCGGCGGCTCGGGGTCCA
CGGGTGGCGCCGTCGGGGGCAAGGGTGGCTCGGGGGTGGCCGGGCTCCCGCCGCCCCCGTGGGCCGAGACCACCTGGATTTACCACGACG
GCGAGGACACCAAGATGATCGTAGGCGAAGAGAAGAAGTTCCTGCTGCCCTTCTGGCTGCAGGTGATCTTCATTTCGCTGCTGCTGTGCC
TGTCGGGCATGTTCAGCGGCCTCAACCTGGGGCTCATGGCCCTGGACCCGATGGAGCTGCGCATCGTGCAGAACTGCGGCACGGAGAAGG
AGAAGAATTACGCCAAGCGCATCGAGCCGGTGCGCAGGCAGGGCAACTACCTGCTGTGCTCACTGCTGCTGGGCAACGTGCTGGTCAACA
CCACGCTCACCATCCTGCTCGACGACATCGCCGGCTCGGGCCTCGTGGCCGTGGTAGTCTCCACCATCGGTATCGTCATCTTCGGAGAGA
TCGTGCCCCAGGCCATCTGCTCCCGGCATGGCCTGGCTGTGGGGGCCAACACCATCTTCCTCACCAAGTTTTTCATGATGATGACCTTCC
CCGCTTCCTACCCGGTCAGCAAGCTGCTGGACTGCGTCCTGGGCCAGGAGATAGGCACCGTCTATAACCGGGAAAAACTGCTGGAGATGC
TCCGGGTCACCGATCCCTACAACGACCTCGTTAAGGAGGAGCTGAACATCATCCAAGGGGCGCTGGAGCTCCGCACCAAGACGGTGGAGG
ACGTGATGACCCCACTCCGGGACTGCTTCATGATCACCGGCGAAGCCATCCTGGACTTCAACACCATGTCTGAGATCATGGAGAGCGGCT
ACACCCGCATTCCAGTGTTTGAAGGGGAGCGCTCCAATATCGTGGACCTGCTGTTTGTCAAAGACTTGGCCTTCGTGGATCCCGATGACT
GTACCCCCCTGAAAACCATCACCAAATTTTATAACCACCCCTTGCACTTTGTTTTCAATGACACCAAGTTGGACGCTATGCTGGAAGAAT
TTAAGAAAGATGATGACCACTGGATCGTCGACACAGACTACGACACGTATGCCGTGCAGTACTCCTGCCGCCTCCTGAACCTCGATGGCA
CCTGTGCTGACAGCTACTCCTTCGTGTTTTCCCGGGACCCCAACGGCCTGCCCCCAGAAGCGCAGAAGATTGTAAGGCAGCGGCAGGAGG
AGCTGTGCCTGGCCAGGCAGTACAGGCTGATCGTCCACAACGGTTACTGCGATGGCAGATCAGAAAGAAACCTTTTGTAGCAATATCAAG
AATCTAGTTTCATCTGAGAACTTCTGATTAGCTCTCAGTCTTCAGCTCTATTTATCTTAGGAGTTTAATTTGCCCTTCTCTCCCCATCTT

>In-frame_ENST00000369878_ENST00000371469_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(amino acids)=623AA_start in transcript=188_stop in transcript=2059
MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEG
GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPL
RKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSG
MFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVP
QAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVM
TPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK

--------------------------------------------------------------
>In-frame_ENST00000433628_ENST00000371464_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(transcript)=2384nt_BP=1745nt
AGTCAGGGAGGCGAACTGCTGAGCACTGGCCGCGGACGCTCCGTTGCAGTCTCGCCCAGGGGCCGGTACCTGCGCTCGCGCCGCCGGGTT
GAAAGGATGAAGCCGCAGCTGGAGCAGCCACCCTATGATTGGCTGTGGCGCTTGTGAACCCAAAGTAAAGATGGCGGGCGGGCAGGCAGC
CGCCGCACTGCCCACTTGGAAGATGGCGGCGCGCCGCAGCCTCAGCGCTCGCGGCCGGGGGATCCTGCAGGCGGCTGCGGGGCGGCTGCT
GCCGCTGCTCCTGCTGAGCTGCTGCTGCGGTGCGGGCGGCTGCGCAGCGGTGGGCGAGAATGAGGAGACGGTGATCATCGGGCTGCGACT
GGAGGACACGAACGACGTGTCGTTCATGGAAGGGGGGGCGCTGCGGGTGAGCGAACGGACCCGGGTCAAGCTGCGGGTGTACGGGCAGAA
CATCAATAACGAGACGTGGTCCCGCATCGCCTTCACCGAGCACGAGCGGCGGCGCCACAGCCCGGGGGAGCGCGGGCTGGGGGGCCCCGC
GCCGCCAGAGCCGGACAGCGGCCCCCAGCGATGCGGCATCCGCACCTCAGACATCATCATCTTGCCCCACATCATTCTCAACCGCCGCAC
CTCGGGCATCATCGAGATCGAGATCAAACCGCTACGCAAGATGGAGAAGAGCAAGTCCTATTACCTGTGCACGTCGCTCTCCACGCCCGC
CCTGGGCGCCGGCGGCTCGGGGTCCACGGGTGGCGCCGTCGGGGGCAAGGGTGGCTCGGGGGTGGCCGGGCTCCCGCCGCCCCCGTGGGC
CGAGACCACCTGGATTTACCACGACGGCGAGGACACCAAGATGATCGTAGGCGAAGAGAAGAAGTTCCTGCTGCCCTTCTGGCTGCAGGT
GATCTTCATTTCGCTGCTGCTGTGCCTGTCGGGCATGTTCAGCGGCCTCAACCTGGGGCTCATGGCCCTGGACCCGATGGAGCTGCGCAT
CGTGCAGAACTGCGGCACGGAGAAGGAGAAGAATTACGCCAAGCGCATCGAGCCGGTGCGCAGGCAGGGCAACTACCTGCTGTGCTCACT
GCTGCTGGGCAACGTGCTGGTCAACACCACGCTCACCATCCTGCTCGACGACATCGCCGGCTCGGGCCTCGTGGCCGTGGTAGTCTCCAC
CATCGGTATCGTCATCTTCGGAGAGATCGTGCCCCAGGCCATCTGCTCCCGGCATGGCCTGGCTGTGGGGGCCAACACCATCTTCCTCAC
CAAGTTTTTCATGATGATGACCTTCCCCGCTTCCTACCCGGTCAGCAAGCTGCTGGACTGCGTCCTGGGCCAGGAGATAGGCACCGTCTA
TAACCGGGAAAAACTGCTGGAGATGCTCCGGGTCACCGATCCCTACAACGACCTCGTTAAGGAGGAGCTGAACATCATCCAAGGGGCGCT
GGAGCTCCGCACCAAGACGGTGGAGGACGTGATGACCCCACTCCGGGACTGCTTCATGATCACCGGCGAAGCCATCCTGGACTTCAACAC
CATGTCTGAGATCATGGAGAGCGGCTACACCCGCATTCCAGTGTTTGAAGGGGAGCGCTCCAATATCGTGGACCTGCTGTTTGTCAAAGA
CTTGGCCTTCGTGGATCCCGATGACTGTACCCCCCTGAAAACCATCACCAAATTTTATAACCACCCCTTGCACTTTGTTTTCAATGACAC
CAAGTTGGACGCTATGCTGGAAGAATTTAAGAAAGATGATGACCACTGGATCGTCGACACAGACTACGACACGTATGCCGTGCAGTACTC
CTGCCGCCTCCTGAACCTCGATGGCACCTGTGCTGACAGCTACTCCTTCGTGTTTTCCCGGGACCCCAACGGCCTGCCCCCAGAAGCGCA
GAAGATTGTAAGGCAGCGGCAGGAGGAGCTGTGCCTGGCCAGGCAGTACAGGCTGATCGTCCACAACGGTTACTGCGATGGCAGATCAGA
AAGAAACCTTTTGTAGCAATATCAAGAATCTAGTTTCATCTGAGAACTTCTGATTAGCTCTCAGTCTTCAGCTCTATTTATCTTAGGAGT
TTAATTTGCCCTTCTCTCCCCATCTTCCCTCAGTTCCCATAAAACCTTCATTACACATAAAGATACACGTGGGGGTCAGTGAATCTGCTT
GCCTTTCCTGAAAGTTTCTGGGGCTTAAGATTCCAGACTCTGATTCATTAAACTATAGTCACCCGTGTCCTGTGATTTTAGTTTTCATTT
GTGTTTATGTCTGTGCTGCAGACGGATGGGTGGGGTGCGCTTCTTTATACCAGGAGCACGTGGCTCTTTCTGACCTTTGGCCTGTTCTAG

>In-frame_ENST00000433628_ENST00000371464_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(amino acids)=623AA_start in transcript=124_stop in transcript=1995
MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEG
GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPL
RKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSG
MFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVP
QAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVM
TPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK

--------------------------------------------------------------
>In-frame_ENST00000433628_ENST00000371467_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(transcript)=2384nt_BP=1745nt
AGTCAGGGAGGCGAACTGCTGAGCACTGGCCGCGGACGCTCCGTTGCAGTCTCGCCCAGGGGCCGGTACCTGCGCTCGCGCCGCCGGGTT
GAAAGGATGAAGCCGCAGCTGGAGCAGCCACCCTATGATTGGCTGTGGCGCTTGTGAACCCAAAGTAAAGATGGCGGGCGGGCAGGCAGC
CGCCGCACTGCCCACTTGGAAGATGGCGGCGCGCCGCAGCCTCAGCGCTCGCGGCCGGGGGATCCTGCAGGCGGCTGCGGGGCGGCTGCT
GCCGCTGCTCCTGCTGAGCTGCTGCTGCGGTGCGGGCGGCTGCGCAGCGGTGGGCGAGAATGAGGAGACGGTGATCATCGGGCTGCGACT
GGAGGACACGAACGACGTGTCGTTCATGGAAGGGGGGGCGCTGCGGGTGAGCGAACGGACCCGGGTCAAGCTGCGGGTGTACGGGCAGAA
CATCAATAACGAGACGTGGTCCCGCATCGCCTTCACCGAGCACGAGCGGCGGCGCCACAGCCCGGGGGAGCGCGGGCTGGGGGGCCCCGC
GCCGCCAGAGCCGGACAGCGGCCCCCAGCGATGCGGCATCCGCACCTCAGACATCATCATCTTGCCCCACATCATTCTCAACCGCCGCAC
CTCGGGCATCATCGAGATCGAGATCAAACCGCTACGCAAGATGGAGAAGAGCAAGTCCTATTACCTGTGCACGTCGCTCTCCACGCCCGC
CCTGGGCGCCGGCGGCTCGGGGTCCACGGGTGGCGCCGTCGGGGGCAAGGGTGGCTCGGGGGTGGCCGGGCTCCCGCCGCCCCCGTGGGC
CGAGACCACCTGGATTTACCACGACGGCGAGGACACCAAGATGATCGTAGGCGAAGAGAAGAAGTTCCTGCTGCCCTTCTGGCTGCAGGT
GATCTTCATTTCGCTGCTGCTGTGCCTGTCGGGCATGTTCAGCGGCCTCAACCTGGGGCTCATGGCCCTGGACCCGATGGAGCTGCGCAT
CGTGCAGAACTGCGGCACGGAGAAGGAGAAGAATTACGCCAAGCGCATCGAGCCGGTGCGCAGGCAGGGCAACTACCTGCTGTGCTCACT
GCTGCTGGGCAACGTGCTGGTCAACACCACGCTCACCATCCTGCTCGACGACATCGCCGGCTCGGGCCTCGTGGCCGTGGTAGTCTCCAC
CATCGGTATCGTCATCTTCGGAGAGATCGTGCCCCAGGCCATCTGCTCCCGGCATGGCCTGGCTGTGGGGGCCAACACCATCTTCCTCAC
CAAGTTTTTCATGATGATGACCTTCCCCGCTTCCTACCCGGTCAGCAAGCTGCTGGACTGCGTCCTGGGCCAGGAGATAGGCACCGTCTA
TAACCGGGAAAAACTGCTGGAGATGCTCCGGGTCACCGATCCCTACAACGACCTCGTTAAGGAGGAGCTGAACATCATCCAAGGGGCGCT
GGAGCTCCGCACCAAGACGGTGGAGGACGTGATGACCCCACTCCGGGACTGCTTCATGATCACCGGCGAAGCCATCCTGGACTTCAACAC
CATGTCTGAGATCATGGAGAGCGGCTACACCCGCATTCCAGTGTTTGAAGGGGAGCGCTCCAATATCGTGGACCTGCTGTTTGTCAAAGA
CTTGGCCTTCGTGGATCCCGATGACTGTACCCCCCTGAAAACCATCACCAAATTTTATAACCACCCCTTGCACTTTGTTTTCAATGACAC
CAAGTTGGACGCTATGCTGGAAGAATTTAAGAAAGATGATGACCACTGGATCGTCGACACAGACTACGACACGTATGCCGTGCAGTACTC
CTGCCGCCTCCTGAACCTCGATGGCACCTGTGCTGACAGCTACTCCTTCGTGTTTTCCCGGGACCCCAACGGCCTGCCCCCAGAAGCGCA
GAAGATTGTAAGGCAGCGGCAGGAGGAGCTGTGCCTGGCCAGGCAGTACAGGCTGATCGTCCACAACGGTTACTGCGATGGCAGATCAGA
AAGAAACCTTTTGTAGCAATATCAAGAATCTAGTTTCATCTGAGAACTTCTGATTAGCTCTCAGTCTTCAGCTCTATTTATCTTAGGAGT
TTAATTTGCCCTTCTCTCCCCATCTTCCCTCAGTTCCCATAAAACCTTCATTACACATAAAGATACACGTGGGGGTCAGTGAATCTGCTT
GCCTTTCCTGAAAGTTTCTGGGGCTTAAGATTCCAGACTCTGATTCATTAAACTATAGTCACCCGTGTCCTGTGATTTTAGTTTTCATTT
GTGTTTATGTCTGTGCTGCAGACGGATGGGTGGGGTGCGCTTCTTTATACCAGGAGCACGTGGCTCTTTCTGACCTTTGGCCTGTTCTAG

>In-frame_ENST00000433628_ENST00000371467_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(amino acids)=623AA_start in transcript=124_stop in transcript=1995
MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEG
GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPL
RKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSG
MFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVP
QAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVM
TPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK

--------------------------------------------------------------
>In-frame_ENST00000433628_ENST00000371469_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(transcript)=2182nt_BP=1745nt
AGTCAGGGAGGCGAACTGCTGAGCACTGGCCGCGGACGCTCCGTTGCAGTCTCGCCCAGGGGCCGGTACCTGCGCTCGCGCCGCCGGGTT
GAAAGGATGAAGCCGCAGCTGGAGCAGCCACCCTATGATTGGCTGTGGCGCTTGTGAACCCAAAGTAAAGATGGCGGGCGGGCAGGCAGC
CGCCGCACTGCCCACTTGGAAGATGGCGGCGCGCCGCAGCCTCAGCGCTCGCGGCCGGGGGATCCTGCAGGCGGCTGCGGGGCGGCTGCT
GCCGCTGCTCCTGCTGAGCTGCTGCTGCGGTGCGGGCGGCTGCGCAGCGGTGGGCGAGAATGAGGAGACGGTGATCATCGGGCTGCGACT
GGAGGACACGAACGACGTGTCGTTCATGGAAGGGGGGGCGCTGCGGGTGAGCGAACGGACCCGGGTCAAGCTGCGGGTGTACGGGCAGAA
CATCAATAACGAGACGTGGTCCCGCATCGCCTTCACCGAGCACGAGCGGCGGCGCCACAGCCCGGGGGAGCGCGGGCTGGGGGGCCCCGC
GCCGCCAGAGCCGGACAGCGGCCCCCAGCGATGCGGCATCCGCACCTCAGACATCATCATCTTGCCCCACATCATTCTCAACCGCCGCAC
CTCGGGCATCATCGAGATCGAGATCAAACCGCTACGCAAGATGGAGAAGAGCAAGTCCTATTACCTGTGCACGTCGCTCTCCACGCCCGC
CCTGGGCGCCGGCGGCTCGGGGTCCACGGGTGGCGCCGTCGGGGGCAAGGGTGGCTCGGGGGTGGCCGGGCTCCCGCCGCCCCCGTGGGC
CGAGACCACCTGGATTTACCACGACGGCGAGGACACCAAGATGATCGTAGGCGAAGAGAAGAAGTTCCTGCTGCCCTTCTGGCTGCAGGT
GATCTTCATTTCGCTGCTGCTGTGCCTGTCGGGCATGTTCAGCGGCCTCAACCTGGGGCTCATGGCCCTGGACCCGATGGAGCTGCGCAT
CGTGCAGAACTGCGGCACGGAGAAGGAGAAGAATTACGCCAAGCGCATCGAGCCGGTGCGCAGGCAGGGCAACTACCTGCTGTGCTCACT
GCTGCTGGGCAACGTGCTGGTCAACACCACGCTCACCATCCTGCTCGACGACATCGCCGGCTCGGGCCTCGTGGCCGTGGTAGTCTCCAC
CATCGGTATCGTCATCTTCGGAGAGATCGTGCCCCAGGCCATCTGCTCCCGGCATGGCCTGGCTGTGGGGGCCAACACCATCTTCCTCAC
CAAGTTTTTCATGATGATGACCTTCCCCGCTTCCTACCCGGTCAGCAAGCTGCTGGACTGCGTCCTGGGCCAGGAGATAGGCACCGTCTA
TAACCGGGAAAAACTGCTGGAGATGCTCCGGGTCACCGATCCCTACAACGACCTCGTTAAGGAGGAGCTGAACATCATCCAAGGGGCGCT
GGAGCTCCGCACCAAGACGGTGGAGGACGTGATGACCCCACTCCGGGACTGCTTCATGATCACCGGCGAAGCCATCCTGGACTTCAACAC
CATGTCTGAGATCATGGAGAGCGGCTACACCCGCATTCCAGTGTTTGAAGGGGAGCGCTCCAATATCGTGGACCTGCTGTTTGTCAAAGA
CTTGGCCTTCGTGGATCCCGATGACTGTACCCCCCTGAAAACCATCACCAAATTTTATAACCACCCCTTGCACTTTGTTTTCAATGACAC
CAAGTTGGACGCTATGCTGGAAGAATTTAAGAAAGATGATGACCACTGGATCGTCGACACAGACTACGACACGTATGCCGTGCAGTACTC
CTGCCGCCTCCTGAACCTCGATGGCACCTGTGCTGACAGCTACTCCTTCGTGTTTTCCCGGGACCCCAACGGCCTGCCCCCAGAAGCGCA
GAAGATTGTAAGGCAGCGGCAGGAGGAGCTGTGCCTGGCCAGGCAGTACAGGCTGATCGTCCACAACGGTTACTGCGATGGCAGATCAGA
AAGAAACCTTTTGTAGCAATATCAAGAATCTAGTTTCATCTGAGAACTTCTGATTAGCTCTCAGTCTTCAGCTCTATTTATCTTAGGAGT
TTAATTTGCCCTTCTCTCCCCATCTTCCCTCAGTTCCCATAAAACCTTCATTACACATAAAGATACACGTGGGGGTCAGTGAATCTGCTT

>In-frame_ENST00000433628_ENST00000371469_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(amino acids)=623AA_start in transcript=124_stop in transcript=1995
MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEG
GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPL
RKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSG
MFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVP
QAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVM
TPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK

--------------------------------------------------------------
>In-frame_ENST00000369875_ENST00000371464_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(transcript)=2424nt_BP=1785nt
GCCTCGGGGTTCCTCAGCTGGCTGAGGTGGAGTCAGTGTCAGTCAGGGAGGCGAACTGCTGAGCACTGGCCGCGGACGCTCCGTTGCAGT
CTCGCCCAGGGGCCGGTACCTGCGCTCGCGCCGCCGGGTTGAAAGGATGAAGCCGCAGCTGGAGCAGCCACCCTATGATTGGCTGTGGCG
CTTGTGAACCCAAAGTAAAGATGGCGGGCGGGCAGGCAGCCGCCGCACTGCCCACTTGGAAGATGGCGGCGCGCCGCAGCCTCAGCGCTC
GCGGCCGGGGGATCCTGCAGGCGGCTGCGGGGCGGCTGCTGCCGCTGCTCCTGCTGAGCTGCTGCTGCGGTGCGGGCGGCTGCGCAGCGG
TGGGCGAGAATGAGGAGACGGTGATCATCGGGCTGCGACTGGAGGACACGAACGACGTGTCGTTCATGGAAGGGGGGGCGCTGCGGGTGA
GCGAACGGACCCGGGTCAAGCTGCGGGTGTACGGGCAGAACATCAATAACGAGACGTGGTCCCGCATCGCCTTCACCGAGCACGAGCGGC
GGCGCCACAGCCCGGGGGAGCGCGGGCTGGGGGGCCCCGCGCCGCCAGAGCCGGACAGCGGCCCCCAGCGATGCGGCATCCGCACCTCAG
ACATCATCATCTTGCCCCACATCATTCTCAACCGCCGCACCTCGGGCATCATCGAGATCGAGATCAAACCGCTACGCAAGATGGAGAAGA
GCAAGTCCTATTACCTGTGCACGTCGCTCTCCACGCCCGCCCTGGGCGCCGGCGGCTCGGGGTCCACGGGTGGCGCCGTCGGGGGCAAGG
GTGGCTCGGGGGTGGCCGGGCTCCCGCCGCCCCCGTGGGCCGAGACCACCTGGATTTACCACGACGGCGAGGACACCAAGATGATCGTAG
GCGAAGAGAAGAAGTTCCTGCTGCCCTTCTGGCTGCAGGTGATCTTCATTTCGCTGCTGCTGTGCCTGTCGGGCATGTTCAGCGGCCTCA
ACCTGGGGCTCATGGCCCTGGACCCGATGGAGCTGCGCATCGTGCAGAACTGCGGCACGGAGAAGGAGAAGAATTACGCCAAGCGCATCG
AGCCGGTGCGCAGGCAGGGCAACTACCTGCTGTGCTCACTGCTGCTGGGCAACGTGCTGGTCAACACCACGCTCACCATCCTGCTCGACG
ACATCGCCGGCTCGGGCCTCGTGGCCGTGGTAGTCTCCACCATCGGTATCGTCATCTTCGGAGAGATCGTGCCCCAGGCCATCTGCTCCC
GGCATGGCCTGGCTGTGGGGGCCAACACCATCTTCCTCACCAAGTTTTTCATGATGATGACCTTCCCCGCTTCCTACCCGGTCAGCAAGC
TGCTGGACTGCGTCCTGGGCCAGGAGATAGGCACCGTCTATAACCGGGAAAAACTGCTGGAGATGCTCCGGGTCACCGATCCCTACAACG
ACCTCGTTAAGGAGGAGCTGAACATCATCCAAGGGGCGCTGGAGCTCCGCACCAAGACGGTGGAGGACGTGATGACCCCACTCCGGGACT
GCTTCATGATCACCGGCGAAGCCATCCTGGACTTCAACACCATGTCTGAGATCATGGAGAGCGGCTACACCCGCATTCCAGTGTTTGAAG
GGGAGCGCTCCAATATCGTGGACCTGCTGTTTGTCAAAGACTTGGCCTTCGTGGATCCCGATGACTGTACCCCCCTGAAAACCATCACCA
AATTTTATAACCACCCCTTGCACTTTGTTTTCAATGACACCAAGTTGGACGCTATGCTGGAAGAATTTAAGAAAGATGATGACCACTGGA
TCGTCGACACAGACTACGACACGTATGCCGTGCAGTACTCCTGCCGCCTCCTGAACCTCGATGGCACCTGTGCTGACAGCTACTCCTTCG
TGTTTTCCCGGGACCCCAACGGCCTGCCCCCAGAAGCGCAGAAGATTGTAAGGCAGCGGCAGGAGGAGCTGTGCCTGGCCAGGCAGTACA
GGCTGATCGTCCACAACGGTTACTGCGATGGCAGATCAGAAAGAAACCTTTTGTAGCAATATCAAGAATCTAGTTTCATCTGAGAACTTC
TGATTAGCTCTCAGTCTTCAGCTCTATTTATCTTAGGAGTTTAATTTGCCCTTCTCTCCCCATCTTCCCTCAGTTCCCATAAAACCTTCA
TTACACATAAAGATACACGTGGGGGTCAGTGAATCTGCTTGCCTTTCCTGAAAGTTTCTGGGGCTTAAGATTCCAGACTCTGATTCATTA
AACTATAGTCACCCGTGTCCTGTGATTTTAGTTTTCATTTGTGTTTATGTCTGTGCTGCAGACGGATGGGTGGGGTGCGCTTCTTTATAC

>In-frame_ENST00000369875_ENST00000371464_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(amino acids)=623AA_start in transcript=164_stop in transcript=2035
MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEG
GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPL
RKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSG
MFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVP
QAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVM
TPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK

--------------------------------------------------------------
>In-frame_ENST00000369875_ENST00000371467_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(transcript)=2424nt_BP=1785nt
GCCTCGGGGTTCCTCAGCTGGCTGAGGTGGAGTCAGTGTCAGTCAGGGAGGCGAACTGCTGAGCACTGGCCGCGGACGCTCCGTTGCAGT
CTCGCCCAGGGGCCGGTACCTGCGCTCGCGCCGCCGGGTTGAAAGGATGAAGCCGCAGCTGGAGCAGCCACCCTATGATTGGCTGTGGCG
CTTGTGAACCCAAAGTAAAGATGGCGGGCGGGCAGGCAGCCGCCGCACTGCCCACTTGGAAGATGGCGGCGCGCCGCAGCCTCAGCGCTC
GCGGCCGGGGGATCCTGCAGGCGGCTGCGGGGCGGCTGCTGCCGCTGCTCCTGCTGAGCTGCTGCTGCGGTGCGGGCGGCTGCGCAGCGG
TGGGCGAGAATGAGGAGACGGTGATCATCGGGCTGCGACTGGAGGACACGAACGACGTGTCGTTCATGGAAGGGGGGGCGCTGCGGGTGA
GCGAACGGACCCGGGTCAAGCTGCGGGTGTACGGGCAGAACATCAATAACGAGACGTGGTCCCGCATCGCCTTCACCGAGCACGAGCGGC
GGCGCCACAGCCCGGGGGAGCGCGGGCTGGGGGGCCCCGCGCCGCCAGAGCCGGACAGCGGCCCCCAGCGATGCGGCATCCGCACCTCAG
ACATCATCATCTTGCCCCACATCATTCTCAACCGCCGCACCTCGGGCATCATCGAGATCGAGATCAAACCGCTACGCAAGATGGAGAAGA
GCAAGTCCTATTACCTGTGCACGTCGCTCTCCACGCCCGCCCTGGGCGCCGGCGGCTCGGGGTCCACGGGTGGCGCCGTCGGGGGCAAGG
GTGGCTCGGGGGTGGCCGGGCTCCCGCCGCCCCCGTGGGCCGAGACCACCTGGATTTACCACGACGGCGAGGACACCAAGATGATCGTAG
GCGAAGAGAAGAAGTTCCTGCTGCCCTTCTGGCTGCAGGTGATCTTCATTTCGCTGCTGCTGTGCCTGTCGGGCATGTTCAGCGGCCTCA
ACCTGGGGCTCATGGCCCTGGACCCGATGGAGCTGCGCATCGTGCAGAACTGCGGCACGGAGAAGGAGAAGAATTACGCCAAGCGCATCG
AGCCGGTGCGCAGGCAGGGCAACTACCTGCTGTGCTCACTGCTGCTGGGCAACGTGCTGGTCAACACCACGCTCACCATCCTGCTCGACG
ACATCGCCGGCTCGGGCCTCGTGGCCGTGGTAGTCTCCACCATCGGTATCGTCATCTTCGGAGAGATCGTGCCCCAGGCCATCTGCTCCC
GGCATGGCCTGGCTGTGGGGGCCAACACCATCTTCCTCACCAAGTTTTTCATGATGATGACCTTCCCCGCTTCCTACCCGGTCAGCAAGC
TGCTGGACTGCGTCCTGGGCCAGGAGATAGGCACCGTCTATAACCGGGAAAAACTGCTGGAGATGCTCCGGGTCACCGATCCCTACAACG
ACCTCGTTAAGGAGGAGCTGAACATCATCCAAGGGGCGCTGGAGCTCCGCACCAAGACGGTGGAGGACGTGATGACCCCACTCCGGGACT
GCTTCATGATCACCGGCGAAGCCATCCTGGACTTCAACACCATGTCTGAGATCATGGAGAGCGGCTACACCCGCATTCCAGTGTTTGAAG
GGGAGCGCTCCAATATCGTGGACCTGCTGTTTGTCAAAGACTTGGCCTTCGTGGATCCCGATGACTGTACCCCCCTGAAAACCATCACCA
AATTTTATAACCACCCCTTGCACTTTGTTTTCAATGACACCAAGTTGGACGCTATGCTGGAAGAATTTAAGAAAGATGATGACCACTGGA
TCGTCGACACAGACTACGACACGTATGCCGTGCAGTACTCCTGCCGCCTCCTGAACCTCGATGGCACCTGTGCTGACAGCTACTCCTTCG
TGTTTTCCCGGGACCCCAACGGCCTGCCCCCAGAAGCGCAGAAGATTGTAAGGCAGCGGCAGGAGGAGCTGTGCCTGGCCAGGCAGTACA
GGCTGATCGTCCACAACGGTTACTGCGATGGCAGATCAGAAAGAAACCTTTTGTAGCAATATCAAGAATCTAGTTTCATCTGAGAACTTC
TGATTAGCTCTCAGTCTTCAGCTCTATTTATCTTAGGAGTTTAATTTGCCCTTCTCTCCCCATCTTCCCTCAGTTCCCATAAAACCTTCA
TTACACATAAAGATACACGTGGGGGTCAGTGAATCTGCTTGCCTTTCCTGAAAGTTTCTGGGGCTTAAGATTCCAGACTCTGATTCATTA
AACTATAGTCACCCGTGTCCTGTGATTTTAGTTTTCATTTGTGTTTATGTCTGTGCTGCAGACGGATGGGTGGGGTGCGCTTCTTTATAC

>In-frame_ENST00000369875_ENST00000371467_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(amino acids)=623AA_start in transcript=164_stop in transcript=2035
MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEG
GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPL
RKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSG
MFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVP
QAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVM
TPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK

--------------------------------------------------------------
>In-frame_ENST00000369875_ENST00000371469_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(transcript)=2222nt_BP=1785nt
GCCTCGGGGTTCCTCAGCTGGCTGAGGTGGAGTCAGTGTCAGTCAGGGAGGCGAACTGCTGAGCACTGGCCGCGGACGCTCCGTTGCAGT
CTCGCCCAGGGGCCGGTACCTGCGCTCGCGCCGCCGGGTTGAAAGGATGAAGCCGCAGCTGGAGCAGCCACCCTATGATTGGCTGTGGCG
CTTGTGAACCCAAAGTAAAGATGGCGGGCGGGCAGGCAGCCGCCGCACTGCCCACTTGGAAGATGGCGGCGCGCCGCAGCCTCAGCGCTC
GCGGCCGGGGGATCCTGCAGGCGGCTGCGGGGCGGCTGCTGCCGCTGCTCCTGCTGAGCTGCTGCTGCGGTGCGGGCGGCTGCGCAGCGG
TGGGCGAGAATGAGGAGACGGTGATCATCGGGCTGCGACTGGAGGACACGAACGACGTGTCGTTCATGGAAGGGGGGGCGCTGCGGGTGA
GCGAACGGACCCGGGTCAAGCTGCGGGTGTACGGGCAGAACATCAATAACGAGACGTGGTCCCGCATCGCCTTCACCGAGCACGAGCGGC
GGCGCCACAGCCCGGGGGAGCGCGGGCTGGGGGGCCCCGCGCCGCCAGAGCCGGACAGCGGCCCCCAGCGATGCGGCATCCGCACCTCAG
ACATCATCATCTTGCCCCACATCATTCTCAACCGCCGCACCTCGGGCATCATCGAGATCGAGATCAAACCGCTACGCAAGATGGAGAAGA
GCAAGTCCTATTACCTGTGCACGTCGCTCTCCACGCCCGCCCTGGGCGCCGGCGGCTCGGGGTCCACGGGTGGCGCCGTCGGGGGCAAGG
GTGGCTCGGGGGTGGCCGGGCTCCCGCCGCCCCCGTGGGCCGAGACCACCTGGATTTACCACGACGGCGAGGACACCAAGATGATCGTAG
GCGAAGAGAAGAAGTTCCTGCTGCCCTTCTGGCTGCAGGTGATCTTCATTTCGCTGCTGCTGTGCCTGTCGGGCATGTTCAGCGGCCTCA
ACCTGGGGCTCATGGCCCTGGACCCGATGGAGCTGCGCATCGTGCAGAACTGCGGCACGGAGAAGGAGAAGAATTACGCCAAGCGCATCG
AGCCGGTGCGCAGGCAGGGCAACTACCTGCTGTGCTCACTGCTGCTGGGCAACGTGCTGGTCAACACCACGCTCACCATCCTGCTCGACG
ACATCGCCGGCTCGGGCCTCGTGGCCGTGGTAGTCTCCACCATCGGTATCGTCATCTTCGGAGAGATCGTGCCCCAGGCCATCTGCTCCC
GGCATGGCCTGGCTGTGGGGGCCAACACCATCTTCCTCACCAAGTTTTTCATGATGATGACCTTCCCCGCTTCCTACCCGGTCAGCAAGC
TGCTGGACTGCGTCCTGGGCCAGGAGATAGGCACCGTCTATAACCGGGAAAAACTGCTGGAGATGCTCCGGGTCACCGATCCCTACAACG
ACCTCGTTAAGGAGGAGCTGAACATCATCCAAGGGGCGCTGGAGCTCCGCACCAAGACGGTGGAGGACGTGATGACCCCACTCCGGGACT
GCTTCATGATCACCGGCGAAGCCATCCTGGACTTCAACACCATGTCTGAGATCATGGAGAGCGGCTACACCCGCATTCCAGTGTTTGAAG
GGGAGCGCTCCAATATCGTGGACCTGCTGTTTGTCAAAGACTTGGCCTTCGTGGATCCCGATGACTGTACCCCCCTGAAAACCATCACCA
AATTTTATAACCACCCCTTGCACTTTGTTTTCAATGACACCAAGTTGGACGCTATGCTGGAAGAATTTAAGAAAGATGATGACCACTGGA
TCGTCGACACAGACTACGACACGTATGCCGTGCAGTACTCCTGCCGCCTCCTGAACCTCGATGGCACCTGTGCTGACAGCTACTCCTTCG
TGTTTTCCCGGGACCCCAACGGCCTGCCCCCAGAAGCGCAGAAGATTGTAAGGCAGCGGCAGGAGGAGCTGTGCCTGGCCAGGCAGTACA
GGCTGATCGTCCACAACGGTTACTGCGATGGCAGATCAGAAAGAAACCTTTTGTAGCAATATCAAGAATCTAGTTTCATCTGAGAACTTC
TGATTAGCTCTCAGTCTTCAGCTCTATTTATCTTAGGAGTTTAATTTGCCCTTCTCTCCCCATCTTCCCTCAGTTCCCATAAAACCTTCA

>In-frame_ENST00000369875_ENST00000371469_TCGA-30-1714-01A_CNNM2_chr10_104679858_+_RBP4_chr10_95353792_length(amino acids)=623AA_start in transcript=164_stop in transcript=2035
MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEG
GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPL
RKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSG
MFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVP
QAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVM
TPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CNNM2-RBP4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CNNM2-RBP4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CNNM2-RBP4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCNNM2C0036341Schizophrenia2PSYGENET
HgeneCNNM2C3151295HYPOMAGNESEMIA 6, RENAL2CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneCNNM2C4225333HYPOMAGNESEMIA, SEIZURES, AND MENTAL RETARDATION2CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneCNNM2C0003811Cardiac Arrhythmia1CTD_human
HgeneCNNM2C0022333Jacksonian Seizure1CTD_human
HgeneCNNM2C0022658Kidney Diseases1CTD_human
HgeneCNNM2C0036572Seizures1CTD_human
HgeneCNNM2C0037768Spasmophilia1CTD_human
HgeneCNNM2C0039621Tetany1CTD_human
HgeneCNNM2C0149958Complex partial seizures1CTD_human
HgeneCNNM2C0234533Generalized seizures1CTD_human
HgeneCNNM2C0234535Clonic Seizures1CTD_human
HgeneCNNM2C0270224Tetany, Neonatal1CTD_human
HgeneCNNM2C0270824Visual seizure1CTD_human
HgeneCNNM2C0270844Tonic Seizures1CTD_human
HgeneCNNM2C0270846Epileptic drop attack1CTD_human
HgeneCNNM2C0422850Seizures, Somatosensory1CTD_human
HgeneCNNM2C0422852Seizures, Auditory1CTD_human
HgeneCNNM2C0422853Olfactory seizure1CTD_human
HgeneCNNM2C0422854Gustatory seizure1CTD_human
HgeneCNNM2C0422855Vertiginous seizure1CTD_human
HgeneCNNM2C0494475Tonic - clonic seizures1CTD_human
HgeneCNNM2C0751056Non-epileptic convulsion1CTD_human
HgeneCNNM2C0751110Single Seizure1CTD_human
HgeneCNNM2C0751123Atonic Absence Seizures1CTD_human
HgeneCNNM2C0751494Convulsive Seizures1CTD_human
HgeneCNNM2C0751495Seizures, Focal1CTD_human
HgeneCNNM2C0751496Seizures, Sensory1CTD_human
HgeneCNNM2C0917812Tetanilla1CTD_human
HgeneCNNM2C3495874Nonepileptic Seizures1CTD_human
HgeneCNNM2C4048158Convulsions1CTD_human
HgeneCNNM2C4316903Absence Seizures1CTD_human
HgeneCNNM2C4317109Epileptic Seizures1CTD_human
HgeneCNNM2C4317123Myoclonic Seizures1CTD_human
HgeneCNNM2C4505436Generalized Absence Seizures1CTD_human
HgeneCNNM2C4510731Familial primary hypomagnesemia with normocalciuria and normocalcemia1ORPHANET
TgeneRBP4C3554593RETINAL DYSTROPHY, IRIS COLOBOMA, AND COMEDOGENIC ACNE SYNDROME4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneRBP4C0000786Spontaneous abortion1CTD_human
TgeneRBP4C0000822Abortion, Tubal1CTD_human
TgeneRBP4C0007097Carcinoma1CTD_human
TgeneRBP4C0018801Heart failure1CTD_human
TgeneRBP4C0018802Congestive heart failure1CTD_human
TgeneRBP4C0022658Kidney Diseases1CTD_human
TgeneRBP4C0023212Left-Sided Heart Failure1CTD_human
TgeneRBP4C0023896Alcoholic Liver Diseases1CTD_human
TgeneRBP4C0024623Malignant neoplasm of stomach1CTD_human
TgeneRBP4C0024667Animal Mammary Neoplasms1CTD_human
TgeneRBP4C0024668Mammary Neoplasms, Experimental1CTD_human
TgeneRBP4C0027540Necrosis1CTD_human
TgeneRBP4C0032460Polycystic Ovary Syndrome1CTD_human
TgeneRBP4C0038356Stomach Neoplasms1CTD_human
TgeneRBP4C0042842Vitamin A Deficiency1CTD_human
TgeneRBP4C0152455Keratomalacia1CTD_human
TgeneRBP4C0205696Anaplastic carcinoma1CTD_human
TgeneRBP4C0205697Carcinoma, Spindle-Cell1CTD_human
TgeneRBP4C0205698Undifferentiated carcinoma1CTD_human
TgeneRBP4C0205699Carcinomatosis1CTD_human
TgeneRBP4C0235527Heart Failure, Right-Sided1CTD_human
TgeneRBP4C0271271Xerotic keratitis1CTD_human
TgeneRBP4C0856901Retinol Deficiency1CTD_human
TgeneRBP4C1136382Sclerocystic Ovaries1CTD_human
TgeneRBP4C1257925Mammary Carcinoma, Animal1CTD_human
TgeneRBP4C1708349Hereditary Diffuse Gastric Cancer1CTD_human
TgeneRBP4C1959583Myocardial Failure1CTD_human
TgeneRBP4C1961112Heart Decompensation1CTD_human
TgeneRBP4C2931501Microphthalmia associated with colobomatous cyst1ORPHANET
TgeneRBP4C3830362Early Pregnancy Loss1CTD_human
TgeneRBP4C4225330MICROPHTHALMIA, ISOLATED, WITH COLOBOMA 101CTD_human;UNIPROT
TgeneRBP4C4552766Miscarriage1CTD_human