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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:COX10-INPP5K (FusionGDB2 ID:18763) |
Fusion Gene Summary for COX10-INPP5K |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: COX10-INPP5K | Fusion gene ID: 18763 | Hgene | Tgene | Gene symbol | COX10 | INPP5K | Gene ID | 1352 | 51763 |
| Gene name | cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 | inositol polyphosphate-5-phosphatase K | |
| Synonyms | - | MDCCAID|PPS|SKIP | |
| Cytomap | 17p12 | 17p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protoheme IX farnesyltransferase, mitochondrialCOX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferaseCOX10, heme A:farnesyltransferase cytochrome c oxidase assembly factorcytochrome c oxidase assembly homolog 10cytochrome c | inositol polyphosphate 5-phosphatase Kphosphatidylinositol-3,4,5-trisphosphate 5-phosphatasephosphatidylinositol-4,5-bisphosphate 5-phosphataseskeletal muscle and kidney-enriched inositol phosphatase | |
| Modification date | 20200313 | 20200327 | |
| UniProtAcc | . | Q9BT40 | |
| Ensembl transtripts involved in fusion gene | ENST00000261643, ENST00000536205, ENST00000537334, ENST00000429152, | ENST00000421807, ENST00000406424, ENST00000320345, ENST00000397335, ENST00000542125, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 4 X 4 X 4=64 |
| # samples | 2 | 5 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(5/64*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: COX10 [Title/Abstract] AND INPP5K [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | COX10(14063264)-INPP5K(1401416), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | INPP5K | GO:0006469 | negative regulation of protein kinase activity | 12556481 |
| Tgene | INPP5K | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation | 12556481 |
| Tgene | INPP5K | GO:0010829 | negative regulation of glucose transmembrane transport | 12556481 |
| Tgene | INPP5K | GO:0016311 | dephosphorylation | 21712384 |
| Tgene | INPP5K | GO:0032869 | cellular response to insulin stimulus | 12556481 |
| Tgene | INPP5K | GO:0033137 | negative regulation of peptidyl-serine phosphorylation | 12556481 |
| Tgene | INPP5K | GO:0043407 | negative regulation of MAP kinase activity | 12556481 |
| Tgene | INPP5K | GO:0043922 | negative regulation by host of viral transcription | 18774950 |
| Tgene | INPP5K | GO:0045719 | negative regulation of glycogen biosynthetic process | 12556481 |
| Tgene | INPP5K | GO:0045869 | negative regulation of single stranded viral RNA replication via double stranded DNA intermediate | 18774950 |
| Tgene | INPP5K | GO:0046627 | negative regulation of insulin receptor signaling pathway | 12556481 |
| Tgene | INPP5K | GO:0046855 | inositol phosphate dephosphorylation | 12536145 |
| Tgene | INPP5K | GO:0046856 | phosphatidylinositol dephosphorylation | 12536145|12556481 |
| Tgene | INPP5K | GO:0051497 | negative regulation of stress fiber assembly | 12556481 |
| Tgene | INPP5K | GO:0051898 | negative regulation of protein kinase B signaling | 12556481 |
| Tgene | INPP5K | GO:0051926 | negative regulation of calcium ion transport | 12556481 |
| Tgene | INPP5K | GO:0071356 | cellular response to tumor necrosis factor | 21712384 |
| Tgene | INPP5K | GO:0071364 | cellular response to epidermal growth factor stimulus | 21712384 |
| Tgene | INPP5K | GO:0090315 | negative regulation of protein targeting to membrane | 12556481 |
| Tgene | INPP5K | GO:0097178 | ruffle assembly | 12556481 |
| Fusion gene breakpoints across COX10 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across INPP5K (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | CHOL | TCGA-W5-AA31-01A | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
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Fusion Gene ORF analysis for COX10-INPP5K |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000261643 | ENST00000421807 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000261643 | ENST00000406424 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000261643 | ENST00000320345 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000261643 | ENST00000397335 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000261643 | ENST00000542125 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000536205 | ENST00000421807 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000536205 | ENST00000406424 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000536205 | ENST00000320345 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000536205 | ENST00000397335 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000536205 | ENST00000542125 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000537334 | ENST00000421807 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000537334 | ENST00000406424 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000537334 | ENST00000320345 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000537334 | ENST00000397335 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| In-frame | ENST00000537334 | ENST00000542125 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| intron-3CDS | ENST00000429152 | ENST00000421807 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| intron-3CDS | ENST00000429152 | ENST00000406424 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| intron-3CDS | ENST00000429152 | ENST00000320345 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| intron-3CDS | ENST00000429152 | ENST00000397335 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| intron-3CDS | ENST00000429152 | ENST00000542125 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000261643 | COX10 | chr17 | 14063264 | - | ENST00000421807 | INPP5K | chr17 | 1401416 | - | 2595 | 772 | 77 | 1342 | 421 |
| ENST00000261643 | COX10 | chr17 | 14063264 | - | ENST00000406424 | INPP5K | chr17 | 1401416 | - | 2557 | 772 | 77 | 1342 | 421 |
| ENST00000261643 | COX10 | chr17 | 14063264 | - | ENST00000320345 | INPP5K | chr17 | 1401416 | - | 2409 | 772 | 77 | 1342 | 421 |
| ENST00000261643 | COX10 | chr17 | 14063264 | - | ENST00000397335 | INPP5K | chr17 | 1401416 | - | 1599 | 772 | 77 | 1342 | 421 |
| ENST00000261643 | COX10 | chr17 | 14063264 | - | ENST00000542125 | INPP5K | chr17 | 1401416 | - | 1536 | 772 | 77 | 1342 | 421 |
| ENST00000536205 | COX10 | chr17 | 14063264 | - | ENST00000421807 | INPP5K | chr17 | 1401416 | - | 2395 | 572 | 453 | 1142 | 229 |
| ENST00000536205 | COX10 | chr17 | 14063264 | - | ENST00000406424 | INPP5K | chr17 | 1401416 | - | 2357 | 572 | 453 | 1142 | 229 |
| ENST00000536205 | COX10 | chr17 | 14063264 | - | ENST00000320345 | INPP5K | chr17 | 1401416 | - | 2209 | 572 | 453 | 1142 | 229 |
| ENST00000536205 | COX10 | chr17 | 14063264 | - | ENST00000397335 | INPP5K | chr17 | 1401416 | - | 1399 | 572 | 453 | 1142 | 229 |
| ENST00000536205 | COX10 | chr17 | 14063264 | - | ENST00000542125 | INPP5K | chr17 | 1401416 | - | 1336 | 572 | 453 | 1142 | 229 |
| ENST00000537334 | COX10 | chr17 | 14063264 | - | ENST00000421807 | INPP5K | chr17 | 1401416 | - | 2198 | 375 | 181 | 945 | 254 |
| ENST00000537334 | COX10 | chr17 | 14063264 | - | ENST00000406424 | INPP5K | chr17 | 1401416 | - | 2160 | 375 | 181 | 945 | 254 |
| ENST00000537334 | COX10 | chr17 | 14063264 | - | ENST00000320345 | INPP5K | chr17 | 1401416 | - | 2012 | 375 | 181 | 945 | 254 |
| ENST00000537334 | COX10 | chr17 | 14063264 | - | ENST00000397335 | INPP5K | chr17 | 1401416 | - | 1202 | 375 | 181 | 945 | 254 |
| ENST00000537334 | COX10 | chr17 | 14063264 | - | ENST00000542125 | INPP5K | chr17 | 1401416 | - | 1139 | 375 | 181 | 945 | 254 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000261643 | ENST00000421807 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.009784981 | 0.99021506 |
| ENST00000261643 | ENST00000406424 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.010311798 | 0.9896882 |
| ENST00000261643 | ENST00000320345 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.011397108 | 0.9886029 |
| ENST00000261643 | ENST00000397335 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.011146069 | 0.98885393 |
| ENST00000261643 | ENST00000542125 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.012492747 | 0.9875072 |
| ENST00000536205 | ENST00000421807 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.007155264 | 0.99284476 |
| ENST00000536205 | ENST00000406424 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.007101742 | 0.9928982 |
| ENST00000536205 | ENST00000320345 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.007750912 | 0.99224913 |
| ENST00000536205 | ENST00000397335 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.007837331 | 0.99216264 |
| ENST00000536205 | ENST00000542125 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.007552322 | 0.9924476 |
| ENST00000537334 | ENST00000421807 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.020174382 | 0.9798257 |
| ENST00000537334 | ENST00000406424 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.019659827 | 0.9803402 |
| ENST00000537334 | ENST00000320345 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.021744087 | 0.9782559 |
| ENST00000537334 | ENST00000397335 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.017579496 | 0.98242056 |
| ENST00000537334 | ENST00000542125 | COX10 | chr17 | 14063264 | - | INPP5K | chr17 | 1401416 | - | 0.017093968 | 0.9829061 |
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Fusion Genomic Features for COX10-INPP5K |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for COX10-INPP5K |
| Go to FGviewer for the breakpoints of chr17:14063264-chr17:1401416 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | INPP5K |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate (PubMed:10753883, PubMed:16824732). Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate (PubMed:10753883). Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle (By similarity). {ECO:0000250|UniProtKB:Q8C5L6, ECO:0000269|PubMed:10753883, ECO:0000269|PubMed:16824732, ECO:0000269|PubMed:28190456, ECO:0000269|PubMed:28190459}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | COX10 | chr17:14063264 | chr17:1401416 | ENST00000261643 | - | 5 | 7 | 174_194 | 231.66666666666666 | 444.0 | Transmembrane | Helical |
| Tgene | INPP5K | chr17:14063264 | chr17:1401416 | ENST00000320345 | 7 | 13 | 321_448 | 182.66666666666666 | 373.0 | Region | Note=Required for ruffle localization | |
| Tgene | INPP5K | chr17:14063264 | chr17:1401416 | ENST00000406424 | 8 | 14 | 321_448 | 182.66666666666666 | 373.0 | Region | Note=Required for ruffle localization | |
| Tgene | INPP5K | chr17:14063264 | chr17:1401416 | ENST00000421807 | 6 | 12 | 321_448 | 258.6666666666667 | 449.0 | Region | Note=Required for ruffle localization |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | COX10 | chr17:14063264 | chr17:1401416 | ENST00000261643 | - | 5 | 7 | 235_255 | 231.66666666666666 | 444.0 | Transmembrane | Helical |
| Hgene | COX10 | chr17:14063264 | chr17:1401416 | ENST00000261643 | - | 5 | 7 | 257_277 | 231.66666666666666 | 444.0 | Transmembrane | Helical |
| Hgene | COX10 | chr17:14063264 | chr17:1401416 | ENST00000261643 | - | 5 | 7 | 280_300 | 231.66666666666666 | 444.0 | Transmembrane | Helical |
| Hgene | COX10 | chr17:14063264 | chr17:1401416 | ENST00000261643 | - | 5 | 7 | 309_329 | 231.66666666666666 | 444.0 | Transmembrane | Helical |
| Hgene | COX10 | chr17:14063264 | chr17:1401416 | ENST00000261643 | - | 5 | 7 | 364_384 | 231.66666666666666 | 444.0 | Transmembrane | Helical |
| Hgene | COX10 | chr17:14063264 | chr17:1401416 | ENST00000261643 | - | 5 | 7 | 411_431 | 231.66666666666666 | 444.0 | Transmembrane | Helical |
| Tgene | INPP5K | chr17:14063264 | chr17:1401416 | ENST00000320345 | 7 | 13 | 16_318 | 182.66666666666666 | 373.0 | Region | Catalytic | |
| Tgene | INPP5K | chr17:14063264 | chr17:1401416 | ENST00000406424 | 8 | 14 | 16_318 | 182.66666666666666 | 373.0 | Region | Catalytic | |
| Tgene | INPP5K | chr17:14063264 | chr17:1401416 | ENST00000421807 | 6 | 12 | 16_318 | 258.6666666666667 | 449.0 | Region | Catalytic |
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Fusion Gene Sequence for COX10-INPP5K |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000261643_ENST00000421807_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=2595nt_BP=772nt GGAAGATGGCGGCGCCCAGCGTCCCGTGAGGAGAGAGGACACAGGGATCCCGGGGAGCGGCCCCAGACTCGTAAATTATGGCCGCATCTC CGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATACAGGACTCCCCTCACA AGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGTATGTCACACAGCTGA ACAGAAGCCACAACCAGCAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAGGTCAAGCCAAAGCAG AAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGTCCAGAAAGCCAAATGAAAAGGAATTGATAGAACTAGAGCCAGACT CAGTAATTGAAGACTCAATAGATGTAGGGAAAGAGACAAAAGAGGAAAAGCGGTGGAAAGAGATGAAGCTGCAAGTGTATGATTTGCCAG GAATTTTGGCTCGACTATCCAAAATCAAACTCACAGCTCTGGTTGTAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTG ACTGGCCCTGTTTCCTGCTTACTTCTGTTGGGACAGGCCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTTTTTGAGGTGCCATTTG ACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCC TGTGGAGGCTGAAGCGGCAGCCCTGTGCTGGCCCCGACACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCA GCCACATGACGTACGGCATCAGCGACCACAAGCCTGTCTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCG TCCTGATGCCCGAGGACCTGTGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACT GGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAATGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACA ACCTGAACCAGGTTTACATCGACATCAGCAATATCCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTG TGGTGGGGATAAGCAGACCCTTCCAGATCCCGCCTGGCTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGA TGGGAGTGAATCCCAGGCGGAGGCCAGAGCTGGCAGCCAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGA AGAGACAGCCAAGTGTCGTCCACATACTCCTCCCAGAGTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAG CCGCTTAAATACAGGTTTTTGTTGCTGAGATGTGAGTGAAACCAGCTAGTGTGTCAACAGTGAAGACCTGGGGACAGTTCTGCGTCTCAT TTCTGGATTCCTACCCCCTCTTCTAGTCTTGCCCAAGTAGTCCTGCCAGGCACATGCCCCATTTGGCACAGGCCTGCATTCTTGTCGTGC CGTCCTGGGCCTCAGGCTGTCTGGGAGGGGAGATGCTCACATTTGTACAGGCTACATAGACTGGTGCAAGCAGTGCTGGATTCCAGGAGT CTTGGCATCTCATAGCTTGTCCCCGTGAGGAGTGAGCAGAGGGTCTGGGATTTCTGCTTTCAGCAAAAGCAGTCTGACTCAGTGGGCAGA ATGGAGGGGCCCCTCTAGCCAGGCTCTTACGCCATGGTTATGAGCAGGTTGATGAGGGTCCTTCGGCCAGCACAACCTTCCTCCCTACTC ACGGCATGGAGTCTGACTGCATGGAAGTTCCAGATCCTGACAGAGAGAACTGGGAAGGATCCAGGTTCGCTTCCGTTGGTAGCTTGAGTC CCATGCCTCCACCCTGCCATCTGAGGAAGGGGTGACAAGTGGTCAAGGAGCTGTGGCCACAGACTTTTCCAGGGTGGTCCTTGGCAGGTG AGGTGCGTCTGTGCCACCCTTGTCAGGAGCCATTGACGACGGGCCCCCCCTGGACCCCCCGGGACCTCAGAGTGGGGGCAGGCAGAAGGG AGAACCAGCTCAAGACATTTTGGAGGATCTGGCCCTGGGGTTCTTCAGAGAACACCCTCTAGGGGCTTTGGGGACATGGCCTGTCCCCAC ATCCAGCACTTGCCTCCGCCATGGTCACTCGGCAGCCCTTTTCCCAGGAGAAGACACCTCTGGGAGCCTGCTCAGTGCTTGTCCTGCCAT CCTGTGTCCTGGGACTGAGGGTTACTCCAGTTGCTCTGTGTTGCATACTCTCCCCCGCAAGCCTGTGTATGAAGAATTGTCCCCTGGCTT >In-frame_ENST00000261643_ENST00000421807_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=421AA_start in transcript=77_stop in transcript=1342 MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMYVTQLNRSHNQQVRPKPEPVASPFLEKTSSG QAKAEIYEMRPLSPPSLSLSRKPNEKELIELEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALA PGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSL RGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKV -------------------------------------------------------------- >In-frame_ENST00000261643_ENST00000406424_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=2557nt_BP=772nt GGAAGATGGCGGCGCCCAGCGTCCCGTGAGGAGAGAGGACACAGGGATCCCGGGGAGCGGCCCCAGACTCGTAAATTATGGCCGCATCTC CGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATACAGGACTCCCCTCACA AGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGTATGTCACACAGCTGA ACAGAAGCCACAACCAGCAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAGGTCAAGCCAAAGCAG AAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGTCCAGAAAGCCAAATGAAAAGGAATTGATAGAACTAGAGCCAGACT CAGTAATTGAAGACTCAATAGATGTAGGGAAAGAGACAAAAGAGGAAAAGCGGTGGAAAGAGATGAAGCTGCAAGTGTATGATTTGCCAG GAATTTTGGCTCGACTATCCAAAATCAAACTCACAGCTCTGGTTGTAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTG ACTGGCCCTGTTTCCTGCTTACTTCTGTTGGGACAGGCCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTTTTTGAGGTGCCATTTG ACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCC TGTGGAGGCTGAAGCGGCAGCCCTGTGCTGGCCCCGACACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCA GCCACATGACGTACGGCATCAGCGACCACAAGCCTGTCTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCG TCCTGATGCCCGAGGACCTGTGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACT GGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAATGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACA ACCTGAACCAGGTTTACATCGACATCAGCAATATCCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTG TGGTGGGGATAAGCAGACCCTTCCAGATCCCGCCTGGCTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGA TGGGAGTGAATCCCAGGCGGAGGCCAGAGCTGGCAGCCAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGA AGAGACAGCCAAGTGTCGTCCACATACTCCTCCCAGAGTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAG CCGCTTAAATACAGGTTTTTGTTGCTGAGATGTGAGTGAAACCAGCTAGTGTGTCAACAGTGAAGACCTGGGGACAGTTCTGCGTCTCAT TTCTGGATTCCTACCCCCTCTTCTAGTCTTGCCCAAGTAGTCCTGCCAGGCACATGCCCCATTTGGCACAGGCCTGCATTCTTGTCGTGC CGTCCTGGGCCTCAGGCTGTCTGGGAGGGGAGATGCTCACATTTGTACAGGCTACATAGACTGGTGCAAGCAGTGCTGGATTCCAGGAGT CTTGGCATCTCATAGCTTGTCCCCGTGAGGAGTGAGCAGAGGGTCTGGGATTTCTGCTTTCAGCAAAAGCAGTCTGACTCAGTGGGCAGA ATGGAGGGGCCCCTCTAGCCAGGCTCTTACGCCATGGTTATGAGCAGGTTGATGAGGGTCCTTCGGCCAGCACAACCTTCCTCCCTACTC ACGGCATGGAGTCTGACTGCATGGAAGTTCCAGATCCTGACAGAGAGAACTGGGAAGGATCCAGGTTCGCTTCCGTTGGTAGCTTGAGTC CCATGCCTCCACCCTGCCATCTGAGGAAGGGGTGACAAGTGGTCAAGGAGCTGTGGCCACAGACTTTTCCAGGGTGGTCCTTGGCAGGTG AGGTGCGTCTGTGCCACCCTTGTCAGGAGCCATTGACGACGGGCCCCCCCTGGACCCCCCGGGACCTCAGAGTGGGGGCAGGCAGAAGGG AGAACCAGCTCAAGACATTTTGGAGGATCTGGCCCTGGGGTTCTTCAGAGAACACCCTCTAGGGGCTTTGGGGACATGGCCTGTCCCCAC ATCCAGCACTTGCCTCCGCCATGGTCACTCGGCAGCCCTTTTCCCAGGAGAAGACACCTCTGGGAGCCTGCTCAGTGCTTGTCCTGCCAT CCTGTGTCCTGGGACTGAGGGTTACTCCAGTTGCTCTGTGTTGCATACTCTCCCCCGCAAGCCTGTGTATGAAGAATTGTCCCCTGGCTT >In-frame_ENST00000261643_ENST00000406424_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=421AA_start in transcript=77_stop in transcript=1342 MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMYVTQLNRSHNQQVRPKPEPVASPFLEKTSSG QAKAEIYEMRPLSPPSLSLSRKPNEKELIELEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALA PGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSL RGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKV -------------------------------------------------------------- >In-frame_ENST00000261643_ENST00000320345_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=2409nt_BP=772nt GGAAGATGGCGGCGCCCAGCGTCCCGTGAGGAGAGAGGACACAGGGATCCCGGGGAGCGGCCCCAGACTCGTAAATTATGGCCGCATCTC CGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATACAGGACTCCCCTCACA AGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGTATGTCACACAGCTGA ACAGAAGCCACAACCAGCAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAGGTCAAGCCAAAGCAG AAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGTCCAGAAAGCCAAATGAAAAGGAATTGATAGAACTAGAGCCAGACT CAGTAATTGAAGACTCAATAGATGTAGGGAAAGAGACAAAAGAGGAAAAGCGGTGGAAAGAGATGAAGCTGCAAGTGTATGATTTGCCAG GAATTTTGGCTCGACTATCCAAAATCAAACTCACAGCTCTGGTTGTAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTG ACTGGCCCTGTTTCCTGCTTACTTCTGTTGGGACAGGCCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTTTTTGAGGTGCCATTTG ACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCC TGTGGAGGCTGAAGCGGCAGCCCTGTGCTGGCCCCGACACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCA GCCACATGACGTACGGCATCAGCGACCACAAGCCTGTCTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCG TCCTGATGCCCGAGGACCTGTGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACT GGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAATGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACA ACCTGAACCAGGTTTACATCGACATCAGCAATATCCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTG TGGTGGGGATAAGCAGACCCTTCCAGATCCCGCCTGGCTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGA TGGGAGTGAATCCCAGGCGGAGGCCAGAGCTGGCAGCCAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGA AGAGACAGCCAAGTGTCGTCCACATACTCCTCCCAGAGTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAG CCGCTTAAATACAGGTTTTTGTTGCTGAGATGTGAGTGAAACCAGCTAGTGTGTCAACAGTGAAGACCTGGGGACAGTTCTGCGTCTCAT TTCTGGATTCCTACCCCCTCTTCTAGTCTTGCCCAAGTAGTCCTGCCAGGCACATGCCCCATTTGGCACAGGCCTGCATTCTTGTCGTGC CGTCCTGGGCCTCAGGCTGTCTGGGAGGGGAGATGCTCACATTTGTACAGGCTACATAGACTGGTGCAAGCAGTGCTGGATTCCAGGAGT CTTGGCATCTCATAGCTTGTCCCCGTGAGGAGTGAGCAGAGGGTCTGGGATTTCTGCTTTCAGCAAAAGCAGTCTGACTCAGTGGGCAGA ATGGAGGGGCCCCTCTAGCCAGGCTCTTACGCCATGGTTATGAGCAGGTTGATGAGGGTCCTTCGGCCAGCACAACCTTCCTCCCTACTC ACGGCATGGAGTCTGACTGCATGGAAGTTCCAGATCCTGACAGAGAGAACTGGGAAGGATCCAGGTTCGCTTCCGTTGGTAGCTTGAGTC CCATGCCTCCACCCTGCCATCTGAGGAAGGGGTGACAAGTGGTCAAGGAGCTGTGGCCACAGACTTTTCCAGGGTGGTCCTTGGCAGGTG AGGTGCGTCTGTGCCACCCTTGTCAGGAGCCATTGACGACGGGCCCCCCCTGGACCCCCCGGGACCTCAGAGTGGGGGCAGGCAGAAGGG AGAACCAGCTCAAGACATTTTGGAGGATCTGGCCCTGGGGTTCTTCAGAGAACACCCTCTAGGGGCTTTGGGGACATGGCCTGTCCCCAC >In-frame_ENST00000261643_ENST00000320345_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=421AA_start in transcript=77_stop in transcript=1342 MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMYVTQLNRSHNQQVRPKPEPVASPFLEKTSSG QAKAEIYEMRPLSPPSLSLSRKPNEKELIELEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALA PGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSL RGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKV -------------------------------------------------------------- >In-frame_ENST00000261643_ENST00000397335_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=1599nt_BP=772nt GGAAGATGGCGGCGCCCAGCGTCCCGTGAGGAGAGAGGACACAGGGATCCCGGGGAGCGGCCCCAGACTCGTAAATTATGGCCGCATCTC CGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATACAGGACTCCCCTCACA AGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGTATGTCACACAGCTGA ACAGAAGCCACAACCAGCAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAGGTCAAGCCAAAGCAG AAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGTCCAGAAAGCCAAATGAAAAGGAATTGATAGAACTAGAGCCAGACT CAGTAATTGAAGACTCAATAGATGTAGGGAAAGAGACAAAAGAGGAAAAGCGGTGGAAAGAGATGAAGCTGCAAGTGTATGATTTGCCAG GAATTTTGGCTCGACTATCCAAAATCAAACTCACAGCTCTGGTTGTAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTG ACTGGCCCTGTTTCCTGCTTACTTCTGTTGGGACAGGCCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTTTTTGAGGTGCCATTTG ACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCC TGTGGAGGCTGAAGCGGCAGCCCTGTGCTGGCCCCGACACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCA GCCACATGACGTACGGCATCAGCGACCACAAGCCTGTCTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCG TCCTGATGCCCGAGGACCTGTGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACT GGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAATGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACA ACCTGAACCAGGTTTACATCGACATCAGCAATATCCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTG TGGTGGGGATAAGCAGACCCTTCCAGATCCCGCCTGGCTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGA TGGGAGTGAATCCCAGGCGGAGGCCAGAGCTGGCAGCCAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGA AGAGACAGCCAAGTGTCGTCCACATACTCCTCCCAGAGTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAG >In-frame_ENST00000261643_ENST00000397335_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=421AA_start in transcript=77_stop in transcript=1342 MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMYVTQLNRSHNQQVRPKPEPVASPFLEKTSSG QAKAEIYEMRPLSPPSLSLSRKPNEKELIELEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALA PGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSL RGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKV -------------------------------------------------------------- >In-frame_ENST00000261643_ENST00000542125_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=1536nt_BP=772nt GGAAGATGGCGGCGCCCAGCGTCCCGTGAGGAGAGAGGACACAGGGATCCCGGGGAGCGGCCCCAGACTCGTAAATTATGGCCGCATCTC CGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATACAGGACTCCCCTCACA AGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGTATGTCACACAGCTGA ACAGAAGCCACAACCAGCAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAGGTCAAGCCAAAGCAG AAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGTCCAGAAAGCCAAATGAAAAGGAATTGATAGAACTAGAGCCAGACT CAGTAATTGAAGACTCAATAGATGTAGGGAAAGAGACAAAAGAGGAAAAGCGGTGGAAAGAGATGAAGCTGCAAGTGTATGATTTGCCAG GAATTTTGGCTCGACTATCCAAAATCAAACTCACAGCTCTGGTTGTAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTG ACTGGCCCTGTTTCCTGCTTACTTCTGTTGGGACAGGCCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTTTTTGAGGTGCCATTTG ACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCC TGTGGAGGCTGAAGCGGCAGCCCTGTGCTGGCCCCGACACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCA GCCACATGACGTACGGCATCAGCGACCACAAGCCTGTCTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCG TCCTGATGCCCGAGGACCTGTGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACT GGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAATGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACA ACCTGAACCAGGTTTACATCGACATCAGCAATATCCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTG TGGTGGGGATAAGCAGACCCTTCCAGATCCCGCCTGGCTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGA TGGGAGTGAATCCCAGGCGGAGGCCAGAGCTGGCAGCCAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGA AGAGACAGCCAAGTGTCGTCCACATACTCCTCCCAGAGTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAG >In-frame_ENST00000261643_ENST00000542125_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=421AA_start in transcript=77_stop in transcript=1342 MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMYVTQLNRSHNQQVRPKPEPVASPFLEKTSSG QAKAEIYEMRPLSPPSLSLSRKPNEKELIELEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALA PGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSL RGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKV -------------------------------------------------------------- >In-frame_ENST00000536205_ENST00000421807_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=2395nt_BP=572nt TTATGGCCGCATCTCCGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATAC AGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGT ATGTCACACAGCTGAACAGAAGCCACAACCAGCAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAG GTCAAGCCAAAGCAGAAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGTCCAGAAAGCCAAATGAAAAGGAATTGATAG AACTAGAGCCAGACTCAGTAATTGAAGACTCAATAGATGTAGGGAAAGAGACAAAAGAGGAAAAGCGGTGGAAAGAGATGAAGCTGCAAG TGTATGATTTGCCAGGAATTTTGGCTCGACTATCCAAAATCAAACTCACAGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACA AAGAACAGACCGCTGGTTCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGCAG CCCTGTGCTGGCCCCGACACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCAGCCACATGACGTACGGCATC AGCGACCACAAGCCTGTCTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCTGATGCCCGAGGACCTG TGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACTGGATTGGACTGTACAAGGTG GGGCTGCGGGACGTTAATGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACATC GACATCAGCAATATCCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTGTGGTGGGGATAAGCAGACCC TTCCAGATCCCGCCTGGCTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGATGGGAGTGAATCCCAGGCGG AGGCCAGAGCTGGCAGCCAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGAAGAGACAGCCAAGTGTCGTC CACATACTCCTCCCAGAGTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAGCCGCTTAAATACAGGTTTTT GTTGCTGAGATGTGAGTGAAACCAGCTAGTGTGTCAACAGTGAAGACCTGGGGACAGTTCTGCGTCTCATTTCTGGATTCCTACCCCCTC TTCTAGTCTTGCCCAAGTAGTCCTGCCAGGCACATGCCCCATTTGGCACAGGCCTGCATTCTTGTCGTGCCGTCCTGGGCCTCAGGCTGT CTGGGAGGGGAGATGCTCACATTTGTACAGGCTACATAGACTGGTGCAAGCAGTGCTGGATTCCAGGAGTCTTGGCATCTCATAGCTTGT CCCCGTGAGGAGTGAGCAGAGGGTCTGGGATTTCTGCTTTCAGCAAAAGCAGTCTGACTCAGTGGGCAGAATGGAGGGGCCCCTCTAGCC AGGCTCTTACGCCATGGTTATGAGCAGGTTGATGAGGGTCCTTCGGCCAGCACAACCTTCCTCCCTACTCACGGCATGGAGTCTGACTGC ATGGAAGTTCCAGATCCTGACAGAGAGAACTGGGAAGGATCCAGGTTCGCTTCCGTTGGTAGCTTGAGTCCCATGCCTCCACCCTGCCAT CTGAGGAAGGGGTGACAAGTGGTCAAGGAGCTGTGGCCACAGACTTTTCCAGGGTGGTCCTTGGCAGGTGAGGTGCGTCTGTGCCACCCT TGTCAGGAGCCATTGACGACGGGCCCCCCCTGGACCCCCCGGGACCTCAGAGTGGGGGCAGGCAGAAGGGAGAACCAGCTCAAGACATTT TGGAGGATCTGGCCCTGGGGTTCTTCAGAGAACACCCTCTAGGGGCTTTGGGGACATGGCCTGTCCCCACATCCAGCACTTGCCTCCGCC ATGGTCACTCGGCAGCCCTTTTCCCAGGAGAAGACACCTCTGGGAGCCTGCTCAGTGCTTGTCCTGCCATCCTGTGTCCTGGGACTGAGG GTTACTCCAGTTGCTCTGTGTTGCATACTCTCCCCCGCAAGCCTGTGTATGAAGAATTGTCCCCTGGCTTCCAGCAGGCCATGGCTGGCT >In-frame_ENST00000536205_ENST00000421807_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=229AA_start in transcript=453_stop in transcript=1142 MICQEFWLDYPKSNSQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGIS DHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYID -------------------------------------------------------------- >In-frame_ENST00000536205_ENST00000406424_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=2357nt_BP=572nt TTATGGCCGCATCTCCGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATAC AGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGT ATGTCACACAGCTGAACAGAAGCCACAACCAGCAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAG GTCAAGCCAAAGCAGAAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGTCCAGAAAGCCAAATGAAAAGGAATTGATAG AACTAGAGCCAGACTCAGTAATTGAAGACTCAATAGATGTAGGGAAAGAGACAAAAGAGGAAAAGCGGTGGAAAGAGATGAAGCTGCAAG TGTATGATTTGCCAGGAATTTTGGCTCGACTATCCAAAATCAAACTCACAGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACA AAGAACAGACCGCTGGTTCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGCAG CCCTGTGCTGGCCCCGACACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCAGCCACATGACGTACGGCATC AGCGACCACAAGCCTGTCTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCTGATGCCCGAGGACCTG TGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACTGGATTGGACTGTACAAGGTG GGGCTGCGGGACGTTAATGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACATC GACATCAGCAATATCCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTGTGGTGGGGATAAGCAGACCC TTCCAGATCCCGCCTGGCTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGATGGGAGTGAATCCCAGGCGG AGGCCAGAGCTGGCAGCCAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGAAGAGACAGCCAAGTGTCGTC CACATACTCCTCCCAGAGTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAGCCGCTTAAATACAGGTTTTT GTTGCTGAGATGTGAGTGAAACCAGCTAGTGTGTCAACAGTGAAGACCTGGGGACAGTTCTGCGTCTCATTTCTGGATTCCTACCCCCTC TTCTAGTCTTGCCCAAGTAGTCCTGCCAGGCACATGCCCCATTTGGCACAGGCCTGCATTCTTGTCGTGCCGTCCTGGGCCTCAGGCTGT CTGGGAGGGGAGATGCTCACATTTGTACAGGCTACATAGACTGGTGCAAGCAGTGCTGGATTCCAGGAGTCTTGGCATCTCATAGCTTGT CCCCGTGAGGAGTGAGCAGAGGGTCTGGGATTTCTGCTTTCAGCAAAAGCAGTCTGACTCAGTGGGCAGAATGGAGGGGCCCCTCTAGCC AGGCTCTTACGCCATGGTTATGAGCAGGTTGATGAGGGTCCTTCGGCCAGCACAACCTTCCTCCCTACTCACGGCATGGAGTCTGACTGC ATGGAAGTTCCAGATCCTGACAGAGAGAACTGGGAAGGATCCAGGTTCGCTTCCGTTGGTAGCTTGAGTCCCATGCCTCCACCCTGCCAT CTGAGGAAGGGGTGACAAGTGGTCAAGGAGCTGTGGCCACAGACTTTTCCAGGGTGGTCCTTGGCAGGTGAGGTGCGTCTGTGCCACCCT TGTCAGGAGCCATTGACGACGGGCCCCCCCTGGACCCCCCGGGACCTCAGAGTGGGGGCAGGCAGAAGGGAGAACCAGCTCAAGACATTT TGGAGGATCTGGCCCTGGGGTTCTTCAGAGAACACCCTCTAGGGGCTTTGGGGACATGGCCTGTCCCCACATCCAGCACTTGCCTCCGCC ATGGTCACTCGGCAGCCCTTTTCCCAGGAGAAGACACCTCTGGGAGCCTGCTCAGTGCTTGTCCTGCCATCCTGTGTCCTGGGACTGAGG GTTACTCCAGTTGCTCTGTGTTGCATACTCTCCCCCGCAAGCCTGTGTATGAAGAATTGTCCCCTGGCTTCCAGCAGGCCATGGCTGGCT >In-frame_ENST00000536205_ENST00000406424_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=229AA_start in transcript=453_stop in transcript=1142 MICQEFWLDYPKSNSQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGIS DHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYID -------------------------------------------------------------- >In-frame_ENST00000536205_ENST00000320345_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=2209nt_BP=572nt TTATGGCCGCATCTCCGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATAC AGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGT ATGTCACACAGCTGAACAGAAGCCACAACCAGCAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAG GTCAAGCCAAAGCAGAAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGTCCAGAAAGCCAAATGAAAAGGAATTGATAG AACTAGAGCCAGACTCAGTAATTGAAGACTCAATAGATGTAGGGAAAGAGACAAAAGAGGAAAAGCGGTGGAAAGAGATGAAGCTGCAAG TGTATGATTTGCCAGGAATTTTGGCTCGACTATCCAAAATCAAACTCACAGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACA AAGAACAGACCGCTGGTTCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGCAG CCCTGTGCTGGCCCCGACACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCAGCCACATGACGTACGGCATC AGCGACCACAAGCCTGTCTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCTGATGCCCGAGGACCTG TGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACTGGATTGGACTGTACAAGGTG GGGCTGCGGGACGTTAATGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACATC GACATCAGCAATATCCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTGTGGTGGGGATAAGCAGACCC TTCCAGATCCCGCCTGGCTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGATGGGAGTGAATCCCAGGCGG AGGCCAGAGCTGGCAGCCAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGAAGAGACAGCCAAGTGTCGTC CACATACTCCTCCCAGAGTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAGCCGCTTAAATACAGGTTTTT GTTGCTGAGATGTGAGTGAAACCAGCTAGTGTGTCAACAGTGAAGACCTGGGGACAGTTCTGCGTCTCATTTCTGGATTCCTACCCCCTC TTCTAGTCTTGCCCAAGTAGTCCTGCCAGGCACATGCCCCATTTGGCACAGGCCTGCATTCTTGTCGTGCCGTCCTGGGCCTCAGGCTGT CTGGGAGGGGAGATGCTCACATTTGTACAGGCTACATAGACTGGTGCAAGCAGTGCTGGATTCCAGGAGTCTTGGCATCTCATAGCTTGT CCCCGTGAGGAGTGAGCAGAGGGTCTGGGATTTCTGCTTTCAGCAAAAGCAGTCTGACTCAGTGGGCAGAATGGAGGGGCCCCTCTAGCC AGGCTCTTACGCCATGGTTATGAGCAGGTTGATGAGGGTCCTTCGGCCAGCACAACCTTCCTCCCTACTCACGGCATGGAGTCTGACTGC ATGGAAGTTCCAGATCCTGACAGAGAGAACTGGGAAGGATCCAGGTTCGCTTCCGTTGGTAGCTTGAGTCCCATGCCTCCACCCTGCCAT CTGAGGAAGGGGTGACAAGTGGTCAAGGAGCTGTGGCCACAGACTTTTCCAGGGTGGTCCTTGGCAGGTGAGGTGCGTCTGTGCCACCCT TGTCAGGAGCCATTGACGACGGGCCCCCCCTGGACCCCCCGGGACCTCAGAGTGGGGGCAGGCAGAAGGGAGAACCAGCTCAAGACATTT TGGAGGATCTGGCCCTGGGGTTCTTCAGAGAACACCCTCTAGGGGCTTTGGGGACATGGCCTGTCCCCACATCCAGCACTTGCCTCCGCC >In-frame_ENST00000536205_ENST00000320345_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=229AA_start in transcript=453_stop in transcript=1142 MICQEFWLDYPKSNSQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGIS DHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYID -------------------------------------------------------------- >In-frame_ENST00000536205_ENST00000397335_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=1399nt_BP=572nt TTATGGCCGCATCTCCGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATAC AGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGT ATGTCACACAGCTGAACAGAAGCCACAACCAGCAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAG GTCAAGCCAAAGCAGAAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGTCCAGAAAGCCAAATGAAAAGGAATTGATAG AACTAGAGCCAGACTCAGTAATTGAAGACTCAATAGATGTAGGGAAAGAGACAAAAGAGGAAAAGCGGTGGAAAGAGATGAAGCTGCAAG TGTATGATTTGCCAGGAATTTTGGCTCGACTATCCAAAATCAAACTCACAGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACA AAGAACAGACCGCTGGTTCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGCAG CCCTGTGCTGGCCCCGACACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCAGCCACATGACGTACGGCATC AGCGACCACAAGCCTGTCTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCTGATGCCCGAGGACCTG TGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACTGGATTGGACTGTACAAGGTG GGGCTGCGGGACGTTAATGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACATC GACATCAGCAATATCCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTGTGGTGGGGATAAGCAGACCC TTCCAGATCCCGCCTGGCTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGATGGGAGTGAATCCCAGGCGG AGGCCAGAGCTGGCAGCCAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGAAGAGACAGCCAAGTGTCGTC CACATACTCCTCCCAGAGTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAGCCGCTTAAATACAGGTTTTT >In-frame_ENST00000536205_ENST00000397335_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=229AA_start in transcript=453_stop in transcript=1142 MICQEFWLDYPKSNSQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGIS DHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYID -------------------------------------------------------------- >In-frame_ENST00000536205_ENST00000542125_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=1336nt_BP=572nt TTATGGCCGCATCTCCGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATAC AGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGT ATGTCACACAGCTGAACAGAAGCCACAACCAGCAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAG GTCAAGCCAAAGCAGAAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGTCCAGAAAGCCAAATGAAAAGGAATTGATAG AACTAGAGCCAGACTCAGTAATTGAAGACTCAATAGATGTAGGGAAAGAGACAAAAGAGGAAAAGCGGTGGAAAGAGATGAAGCTGCAAG TGTATGATTTGCCAGGAATTTTGGCTCGACTATCCAAAATCAAACTCACAGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACA AAGAACAGACCGCTGGTTCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGCAG CCCTGTGCTGGCCCCGACACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCAGCCACATGACGTACGGCATC AGCGACCACAAGCCTGTCTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCTGATGCCCGAGGACCTG TGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACTGGATTGGACTGTACAAGGTG GGGCTGCGGGACGTTAATGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACATC GACATCAGCAATATCCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTGTGGTGGGGATAAGCAGACCC TTCCAGATCCCGCCTGGCTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGATGGGAGTGAATCCCAGGCGG AGGCCAGAGCTGGCAGCCAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGAAGAGACAGCCAAGTGTCGTC >In-frame_ENST00000536205_ENST00000542125_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=229AA_start in transcript=453_stop in transcript=1142 MICQEFWLDYPKSNSQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGIS DHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYID -------------------------------------------------------------- >In-frame_ENST00000537334_ENST00000421807_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=2198nt_BP=375nt TTATGGCCGCATCTCCGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATAC AGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGC TCTGGTTGTAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTGACTGGCCCTGTTTCCTGCTTACTTCTGTTGGGACAGG CCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGT TCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGCAGCCCTGTGCTGGCCCCGA CACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCAGCCACATGACGTACGGCATCAGCGACCACAAGCCTGT CTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCTGATGCCCGAGGACCTGTGGACCGTGGAAAATGA CATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACTGGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAA TGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACATCGACATCAGCAATATCCC TACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTGTGGTGGGGATAAGCAGACCCTTCCAGATCCCGCCTGG CTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGATGGGAGTGAATCCCAGGCGGAGGCCAGAGCTGGCAGC CAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGAAGAGACAGCCAAGTGTCGTCCACATACTCCTCCCAGA GTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAGCCGCTTAAATACAGGTTTTTGTTGCTGAGATGTGAGT GAAACCAGCTAGTGTGTCAACAGTGAAGACCTGGGGACAGTTCTGCGTCTCATTTCTGGATTCCTACCCCCTCTTCTAGTCTTGCCCAAG TAGTCCTGCCAGGCACATGCCCCATTTGGCACAGGCCTGCATTCTTGTCGTGCCGTCCTGGGCCTCAGGCTGTCTGGGAGGGGAGATGCT CACATTTGTACAGGCTACATAGACTGGTGCAAGCAGTGCTGGATTCCAGGAGTCTTGGCATCTCATAGCTTGTCCCCGTGAGGAGTGAGC AGAGGGTCTGGGATTTCTGCTTTCAGCAAAAGCAGTCTGACTCAGTGGGCAGAATGGAGGGGCCCCTCTAGCCAGGCTCTTACGCCATGG TTATGAGCAGGTTGATGAGGGTCCTTCGGCCAGCACAACCTTCCTCCCTACTCACGGCATGGAGTCTGACTGCATGGAAGTTCCAGATCC TGACAGAGAGAACTGGGAAGGATCCAGGTTCGCTTCCGTTGGTAGCTTGAGTCCCATGCCTCCACCCTGCCATCTGAGGAAGGGGTGACA AGTGGTCAAGGAGCTGTGGCCACAGACTTTTCCAGGGTGGTCCTTGGCAGGTGAGGTGCGTCTGTGCCACCCTTGTCAGGAGCCATTGAC GACGGGCCCCCCCTGGACCCCCCGGGACCTCAGAGTGGGGGCAGGCAGAAGGGAGAACCAGCTCAAGACATTTTGGAGGATCTGGCCCTG GGGTTCTTCAGAGAACACCCTCTAGGGGCTTTGGGGACATGGCCTGTCCCCACATCCAGCACTTGCCTCCGCCATGGTCACTCGGCAGCC CTTTTCCCAGGAGAAGACACCTCTGGGAGCCTGCTCAGTGCTTGTCCTGCCATCCTGTGTCCTGGGACTGAGGGTTACTCCAGTTGCTCT GTGTTGCATACTCTCCCCCGCAAGCCTGTGTATGAAGAATTGTCCCCTGGCTTCCAGCAGGCCATGGCTGGCTGTTTTGTGACTGTTACA >In-frame_ENST00000537334_ENST00000421807_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=254AA_start in transcript=181_stop in transcript=945 MVVSTTAAGFALAPGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPD TPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVN -------------------------------------------------------------- >In-frame_ENST00000537334_ENST00000406424_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=2160nt_BP=375nt TTATGGCCGCATCTCCGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATAC AGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGC TCTGGTTGTAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTGACTGGCCCTGTTTCCTGCTTACTTCTGTTGGGACAGG CCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGT TCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGCAGCCCTGTGCTGGCCCCGA CACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCAGCCACATGACGTACGGCATCAGCGACCACAAGCCTGT CTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCTGATGCCCGAGGACCTGTGGACCGTGGAAAATGA CATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACTGGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAA TGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACATCGACATCAGCAATATCCC TACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTGTGGTGGGGATAAGCAGACCCTTCCAGATCCCGCCTGG CTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGATGGGAGTGAATCCCAGGCGGAGGCCAGAGCTGGCAGC CAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGAAGAGACAGCCAAGTGTCGTCCACATACTCCTCCCAGA GTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAGCCGCTTAAATACAGGTTTTTGTTGCTGAGATGTGAGT GAAACCAGCTAGTGTGTCAACAGTGAAGACCTGGGGACAGTTCTGCGTCTCATTTCTGGATTCCTACCCCCTCTTCTAGTCTTGCCCAAG TAGTCCTGCCAGGCACATGCCCCATTTGGCACAGGCCTGCATTCTTGTCGTGCCGTCCTGGGCCTCAGGCTGTCTGGGAGGGGAGATGCT CACATTTGTACAGGCTACATAGACTGGTGCAAGCAGTGCTGGATTCCAGGAGTCTTGGCATCTCATAGCTTGTCCCCGTGAGGAGTGAGC AGAGGGTCTGGGATTTCTGCTTTCAGCAAAAGCAGTCTGACTCAGTGGGCAGAATGGAGGGGCCCCTCTAGCCAGGCTCTTACGCCATGG TTATGAGCAGGTTGATGAGGGTCCTTCGGCCAGCACAACCTTCCTCCCTACTCACGGCATGGAGTCTGACTGCATGGAAGTTCCAGATCC TGACAGAGAGAACTGGGAAGGATCCAGGTTCGCTTCCGTTGGTAGCTTGAGTCCCATGCCTCCACCCTGCCATCTGAGGAAGGGGTGACA AGTGGTCAAGGAGCTGTGGCCACAGACTTTTCCAGGGTGGTCCTTGGCAGGTGAGGTGCGTCTGTGCCACCCTTGTCAGGAGCCATTGAC GACGGGCCCCCCCTGGACCCCCCGGGACCTCAGAGTGGGGGCAGGCAGAAGGGAGAACCAGCTCAAGACATTTTGGAGGATCTGGCCCTG GGGTTCTTCAGAGAACACCCTCTAGGGGCTTTGGGGACATGGCCTGTCCCCACATCCAGCACTTGCCTCCGCCATGGTCACTCGGCAGCC CTTTTCCCAGGAGAAGACACCTCTGGGAGCCTGCTCAGTGCTTGTCCTGCCATCCTGTGTCCTGGGACTGAGGGTTACTCCAGTTGCTCT GTGTTGCATACTCTCCCCCGCAAGCCTGTGTATGAAGAATTGTCCCCTGGCTTCCAGCAGGCCATGGCTGGCTGTTTTGTGACTGTTACA >In-frame_ENST00000537334_ENST00000406424_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=254AA_start in transcript=181_stop in transcript=945 MVVSTTAAGFALAPGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPD TPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVN -------------------------------------------------------------- >In-frame_ENST00000537334_ENST00000320345_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=2012nt_BP=375nt TTATGGCCGCATCTCCGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATAC AGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGC TCTGGTTGTAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTGACTGGCCCTGTTTCCTGCTTACTTCTGTTGGGACAGG CCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGT TCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGCAGCCCTGTGCTGGCCCCGA CACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCAGCCACATGACGTACGGCATCAGCGACCACAAGCCTGT CTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCTGATGCCCGAGGACCTGTGGACCGTGGAAAATGA CATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACTGGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAA TGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACATCGACATCAGCAATATCCC TACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTGTGGTGGGGATAAGCAGACCCTTCCAGATCCCGCCTGG CTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGATGGGAGTGAATCCCAGGCGGAGGCCAGAGCTGGCAGC CAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGAAGAGACAGCCAAGTGTCGTCCACATACTCCTCCCAGA GTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAGCCGCTTAAATACAGGTTTTTGTTGCTGAGATGTGAGT GAAACCAGCTAGTGTGTCAACAGTGAAGACCTGGGGACAGTTCTGCGTCTCATTTCTGGATTCCTACCCCCTCTTCTAGTCTTGCCCAAG TAGTCCTGCCAGGCACATGCCCCATTTGGCACAGGCCTGCATTCTTGTCGTGCCGTCCTGGGCCTCAGGCTGTCTGGGAGGGGAGATGCT CACATTTGTACAGGCTACATAGACTGGTGCAAGCAGTGCTGGATTCCAGGAGTCTTGGCATCTCATAGCTTGTCCCCGTGAGGAGTGAGC AGAGGGTCTGGGATTTCTGCTTTCAGCAAAAGCAGTCTGACTCAGTGGGCAGAATGGAGGGGCCCCTCTAGCCAGGCTCTTACGCCATGG TTATGAGCAGGTTGATGAGGGTCCTTCGGCCAGCACAACCTTCCTCCCTACTCACGGCATGGAGTCTGACTGCATGGAAGTTCCAGATCC TGACAGAGAGAACTGGGAAGGATCCAGGTTCGCTTCCGTTGGTAGCTTGAGTCCCATGCCTCCACCCTGCCATCTGAGGAAGGGGTGACA AGTGGTCAAGGAGCTGTGGCCACAGACTTTTCCAGGGTGGTCCTTGGCAGGTGAGGTGCGTCTGTGCCACCCTTGTCAGGAGCCATTGAC GACGGGCCCCCCCTGGACCCCCCGGGACCTCAGAGTGGGGGCAGGCAGAAGGGAGAACCAGCTCAAGACATTTTGGAGGATCTGGCCCTG GGGTTCTTCAGAGAACACCCTCTAGGGGCTTTGGGGACATGGCCTGTCCCCACATCCAGCACTTGCCTCCGCCATGGTCACTCGGCAGCC >In-frame_ENST00000537334_ENST00000320345_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=254AA_start in transcript=181_stop in transcript=945 MVVSTTAAGFALAPGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPD TPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVN -------------------------------------------------------------- >In-frame_ENST00000537334_ENST00000397335_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=1202nt_BP=375nt TTATGGCCGCATCTCCGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATAC AGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGC TCTGGTTGTAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTGACTGGCCCTGTTTCCTGCTTACTTCTGTTGGGACAGG CCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGT TCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGCAGCCCTGTGCTGGCCCCGA CACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCAGCCACATGACGTACGGCATCAGCGACCACAAGCCTGT CTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCTGATGCCCGAGGACCTGTGGACCGTGGAAAATGA CATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACTGGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAA TGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACATCGACATCAGCAATATCCC TACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTGTGGTGGGGATAAGCAGACCCTTCCAGATCCCGCCTGG CTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGATGGGAGTGAATCCCAGGCGGAGGCCAGAGCTGGCAGC CAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGAAGAGACAGCCAAGTGTCGTCCACATACTCCTCCCAGA GTGAGCTCTAACCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAGCCGCTTAAATACAGGTTTTTGTTGCTGAGATGTGAGT >In-frame_ENST00000537334_ENST00000397335_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=254AA_start in transcript=181_stop in transcript=945 MVVSTTAAGFALAPGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPD TPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVN -------------------------------------------------------------- >In-frame_ENST00000537334_ENST00000542125_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(transcript)=1139nt_BP=375nt TTATGGCCGCATCTCCGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATAC AGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGC TCTGGTTGTAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTGACTGGCCCTGTTTCCTGCTTACTTCTGTTGGGACAGG CCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGT TCGTGGACAGATCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGCAGCCCTGTGCTGGCCCCGA CACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCAGCCACATGACGTACGGCATCAGCGACCACAAGCCTGT CTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCTGATGCCCGAGGACCTGTGGACCGTGGAAAATGA CATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCAGCCCGTGGGACTGGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAA TGACTACGTGTCCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACATCGACATCAGCAATATCCC TACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTGTGGTGGGGATAAGCAGACCCTTCCAGATCCCGCCTGG CTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGATGGGAGTGAATCCCAGGCGGAGGCCAGAGCTGGCAGC CAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGCCTGGCCCCCTGAAGAGACAGCCAAGTGTCGTCCACATACTCCTCCCAGA >In-frame_ENST00000537334_ENST00000542125_TCGA-W5-AA31-01A_COX10_chr17_14063264_-_INPP5K_chr17_1401416_length(amino acids)=254AA_start in transcript=181_stop in transcript=945 MVVSTTAAGFALAPGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISEKKRKPAWTDRILWRLKRQPCAGPD TPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVN -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for COX10-INPP5K |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for COX10-INPP5K |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for COX10-INPP5K |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | COX10 | C0023264 | Leigh Disease | 9 | CLINGEN;CTD_human;GENOMICS_ENGLAND |
| Hgene | COX10 | C1838951 | LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY | 7 | CLINGEN |
| Hgene | COX10 | C1850597 | Leigh Syndrome Due To Mitochondrial Complex II Deficiency | 7 | CLINGEN |
| Hgene | COX10 | C1850598 | Leigh Syndrome due to Mitochondrial Complex III Deficiency | 7 | CLINGEN |
| Hgene | COX10 | C1850599 | Leigh Syndrome due to Mitochondrial Complex IV Deficiency | 7 | CLINGEN |
| Hgene | COX10 | C1850600 | Leigh Syndrome due to Mitochondrial Complex V Deficiency | 7 | CLINGEN |
| Hgene | COX10 | C2931891 | Necrotizing encephalopathy, infantile subacute, of Leigh | 7 | CLINGEN |
| Hgene | COX10 | C0268237 | Cytochrome-c Oxidase Deficiency | 5 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT |
| Hgene | COX10 | C0751651 | Mitochondrial Diseases | 1 | GENOMICS_ENGLAND |
| Tgene | INPP5K | C4479410 | MUSCULAR DYSTROPHY, CONGENITAL, WITH CATARACTS AND INTELLECTUAL DISABILITY | 2 | CTD_human;GENOMICS_ENGLAND;UNIPROT |
| Tgene | INPP5K | C0024814 | Marinesco-Sjogren syndrome | 1 | ORPHANET |
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