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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CPD-HDAC5 (FusionGDB2 ID:18943)

Fusion Gene Summary for CPD-HDAC5

check button Fusion gene summary
Fusion gene informationFusion gene name: CPD-HDAC5
Fusion gene ID: 18943
HgeneTgene
Gene symbol

CPD

HDAC5

Gene ID

9455

10014

Gene namehomer scaffold protein 2histone deacetylase 5
SynonymsACPD|CPD|DFNA68|HOMER-2|VESL-2HD5|NY-CO-9
Cytomap

15q25.2

17q21.31

Type of geneprotein-codingprotein-coding
Descriptionhomer protein homolog 2cupidinhomer homolog 2homer homolog 3homer scaffolding protein 2homer, neuronal immediate early gene, 2histone deacetylase 5antigen NY-CO-9
Modification date2020031320200313
UniProtAcc.

Q9UQL6

Ensembl transtripts involved in fusion geneENST00000225719, ENST00000543464, 
ENST00000584051, 		ENST00000225983, 
ENST00000393622, ENST00000336057, 
ENST00000586802, 
Fusion gene scores* DoF score26 X 16 X 10=416013 X 11 X 8=1144
# samples 2614
** MAII scorelog2(26/4160*10)=-4
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1144*10)=-3.03058831983342
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CPD [Title/Abstract] AND HDAC5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCPD(28712254)-HDAC5(42171202), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneHDAC5

GO:0000122

negative regulation of transcription by RNA polymerase II

16236793

TgeneHDAC5

GO:0016575

histone deacetylation

10869435


check buttonFusion gene breakpoints across CPD (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across HDAC5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-J4-A67T-01ACPDchr17

28712254

+HDAC5chr17

42171202

-
ChimerDB4PRADTCGA-J4-A67TCPDchr17

28712254

+HDAC5chr17

42171202

-
ChimerDB4PRADTCGA-J4-A67T-01ACPDchr17

28712254

-HDAC5chr17

42171202

-


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Fusion Gene ORF analysis for CPD-HDAC5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000225719ENST00000225983CPDchr17

28712254

+HDAC5chr17

42171202

-
In-frameENST00000225719ENST00000393622CPDchr17

28712254

+HDAC5chr17

42171202

-
In-frameENST00000225719ENST00000336057CPDchr17

28712254

+HDAC5chr17

42171202

-
In-frameENST00000225719ENST00000586802CPDchr17

28712254

+HDAC5chr17

42171202

-
In-frameENST00000543464ENST00000225983CPDchr17

28712254

+HDAC5chr17

42171202

-
In-frameENST00000543464ENST00000393622CPDchr17

28712254

+HDAC5chr17

42171202

-
In-frameENST00000543464ENST00000336057CPDchr17

28712254

+HDAC5chr17

42171202

-
In-frameENST00000543464ENST00000586802CPDchr17

28712254

+HDAC5chr17

42171202

-
intron-3CDSENST00000584051ENST00000225983CPDchr17

28712254

+HDAC5chr17

42171202

-
intron-3CDSENST00000584051ENST00000393622CPDchr17

28712254

+HDAC5chr17

42171202

-
intron-3CDSENST00000584051ENST00000336057CPDchr17

28712254

+HDAC5chr17

42171202

-
intron-3CDSENST00000584051ENST00000586802CPDchr17

28712254

+HDAC5chr17

42171202

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000225719CPDchr1728712254+ENST00000225983HDAC5chr1742171202-597510707643441422
ENST00000225719CPDchr1728712254+ENST00000393622HDAC5chr1742171202-596810707643441422
ENST00000225719CPDchr1728712254+ENST00000336057HDAC5chr1742171202-571210707640891337
ENST00000225719CPDchr1728712254+ENST00000586802HDAC5chr1742171202-442710707643441422
ENST00000543464CPDchr1728712254+ENST00000225983HDAC5chr1742171202-556065540239291175
ENST00000543464CPDchr1728712254+ENST00000393622HDAC5chr1742171202-555365540239291175
ENST00000543464CPDchr1728712254+ENST00000336057HDAC5chr1742171202-529765540236741090
ENST00000543464CPDchr1728712254+ENST00000586802HDAC5chr1742171202-401265540239291175

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000225719ENST00000225983CPDchr1728712254+HDAC5chr1742171202-0.0036989670.99630105
ENST00000225719ENST00000393622CPDchr1728712254+HDAC5chr1742171202-0.0037635720.9962365
ENST00000225719ENST00000336057CPDchr1728712254+HDAC5chr1742171202-0.0038390190.996161
ENST00000225719ENST00000586802CPDchr1728712254+HDAC5chr1742171202-0.0101452750.98985475
ENST00000543464ENST00000225983CPDchr1728712254+HDAC5chr1742171202-0.0034845820.9965154
ENST00000543464ENST00000393622CPDchr1728712254+HDAC5chr1742171202-0.0035524970.99644744
ENST00000543464ENST00000336057CPDchr1728712254+HDAC5chr1742171202-0.0035189710.99648094
ENST00000543464ENST00000586802CPDchr1728712254+HDAC5chr1742171202-0.0105722750.98942775

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Fusion Genomic Features for CPD-HDAC5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CPD-HDAC5


check button Go to

FGviewer for the breakpoints of chr17:28712254-chr17:42171202

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.HDAC5

Q9UQL6

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Serves as a corepressor of RARA and causes its deacetylation (PubMed:28167758). In association with RARA, plays a role in the repression of microRNA-10a and thereby in the inflammatory response (PubMed:28167758). {ECO:0000269|PubMed:24413532, ECO:0000269|PubMed:28167758}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCPDchr17:28712254chr17:42171202ENST00000225719+221162_164331.33333333333331381.0MotifCell attachment site
TgeneHDAC5chr17:28712254chr17:42171202ENST000002259832271099_110432.3333333333333361124.0Compositional biasNote=Poly-Ala
TgeneHDAC5chr17:28712254chr17:42171202ENST0000022598322747_5232.3333333333333361124.0Compositional biasNote=Poly-Gly
TgeneHDAC5chr17:28712254chr17:42171202ENST00000225983227596_59932.3333333333333361124.0Compositional biasNote=Poly-Glu
TgeneHDAC5chr17:28712254chr17:42171202ENST0000022598322785_9232.3333333333333361124.0Compositional biasNote=Poly-Gln
TgeneHDAC5chr17:28712254chr17:42171202ENST000003360572251099_110431.3333333333333321038.0Compositional biasNote=Poly-Ala
TgeneHDAC5chr17:28712254chr17:42171202ENST0000033605722547_5231.3333333333333321038.0Compositional biasNote=Poly-Gly
TgeneHDAC5chr17:28712254chr17:42171202ENST00000336057225596_59931.3333333333333321038.0Compositional biasNote=Poly-Glu
TgeneHDAC5chr17:28712254chr17:42171202ENST0000033605722585_9231.3333333333333321038.0Compositional biasNote=Poly-Gln
TgeneHDAC5chr17:28712254chr17:42171202ENST000003936222271099_110431.3333333333333321123.0Compositional biasNote=Poly-Ala
TgeneHDAC5chr17:28712254chr17:42171202ENST0000039362222747_5231.3333333333333321123.0Compositional biasNote=Poly-Gly
TgeneHDAC5chr17:28712254chr17:42171202ENST00000393622227596_59931.3333333333333321123.0Compositional biasNote=Poly-Glu
TgeneHDAC5chr17:28712254chr17:42171202ENST0000039362222785_9231.3333333333333321123.0Compositional biasNote=Poly-Gln
TgeneHDAC5chr17:28712254chr17:42171202ENST000005868022271099_110431.3333333333333321123.0Compositional biasNote=Poly-Ala
TgeneHDAC5chr17:28712254chr17:42171202ENST0000058680222747_5231.3333333333333321123.0Compositional biasNote=Poly-Gly
TgeneHDAC5chr17:28712254chr17:42171202ENST00000586802227596_59931.3333333333333321123.0Compositional biasNote=Poly-Glu
TgeneHDAC5chr17:28712254chr17:42171202ENST0000058680222785_9231.3333333333333321123.0Compositional biasNote=Poly-Gln
TgeneHDAC5chr17:28712254chr17:42171202ENST000002259832271081_112232.3333333333333361124.0MotifNote=Nuclear export signal
TgeneHDAC5chr17:28712254chr17:42171202ENST000003360572251081_112231.3333333333333321038.0MotifNote=Nuclear export signal
TgeneHDAC5chr17:28712254chr17:42171202ENST000003936222271081_112231.3333333333333321123.0MotifNote=Nuclear export signal
TgeneHDAC5chr17:28712254chr17:42171202ENST000005868022271081_112231.3333333333333321123.0MotifNote=Nuclear export signal
TgeneHDAC5chr17:28712254chr17:42171202ENST00000225983227684_102832.3333333333333361124.0RegionNote=Histone deacetylase
TgeneHDAC5chr17:28712254chr17:42171202ENST00000336057225684_102831.3333333333333321038.0RegionNote=Histone deacetylase
TgeneHDAC5chr17:28712254chr17:42171202ENST00000393622227684_102831.3333333333333321123.0RegionNote=Histone deacetylase
TgeneHDAC5chr17:28712254chr17:42171202ENST00000586802227684_102831.3333333333333321123.0RegionNote=Histone deacetylase

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCPDchr17:28712254chr17:42171202ENST00000543464+221162_16484.333333333333331134.0MotifCell attachment site
HgeneCPDchr17:28712254chr17:42171202ENST00000225719+22132_493331.33333333333331381.0RegionNote=Carboxypeptidase-like 1
HgeneCPDchr17:28712254chr17:42171202ENST00000225719+221494_897331.33333333333331381.0RegionNote=Carboxypeptidase-like 2
HgeneCPDchr17:28712254chr17:42171202ENST00000225719+221898_1299331.33333333333331381.0RegionNote=Carboxypeptidase-like 3
HgeneCPDchr17:28712254chr17:42171202ENST00000543464+22132_49384.333333333333331134.0RegionNote=Carboxypeptidase-like 1
HgeneCPDchr17:28712254chr17:42171202ENST00000543464+221494_89784.333333333333331134.0RegionNote=Carboxypeptidase-like 2
HgeneCPDchr17:28712254chr17:42171202ENST00000543464+221898_129984.333333333333331134.0RegionNote=Carboxypeptidase-like 3
HgeneCPDchr17:28712254chr17:42171202ENST00000225719+2211321_1380331.33333333333331381.0Topological domainCytoplasmic
HgeneCPDchr17:28712254chr17:42171202ENST00000225719+22132_1299331.33333333333331381.0Topological domainExtracellular
HgeneCPDchr17:28712254chr17:42171202ENST00000543464+2211321_138084.333333333333331134.0Topological domainCytoplasmic
HgeneCPDchr17:28712254chr17:42171202ENST00000543464+22132_129984.333333333333331134.0Topological domainExtracellular
HgeneCPDchr17:28712254chr17:42171202ENST00000225719+2211300_1320331.33333333333331381.0TransmembraneHelical
HgeneCPDchr17:28712254chr17:42171202ENST00000543464+2211300_132084.333333333333331134.0TransmembraneHelical


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Fusion Gene Sequence for CPD-HDAC5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000225719_ENST00000225983_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(transcript)=5975nt_BP=1070nt
GGGGATCCGGCGGGCCCCCGCCGCCCGGAGCGCTGAGCCGCGGGAGCGGAGCCGGGGTTAGCGGCGCTGCTGGAAGATGGCGAGCGGCCG
GGACGAGCGGCCGCCTTGGCGGCTAGGGCGGCTCCTGTTGCTCATGTGCCTGCTGCTGCTGGGGAGCTCGGCCCGGGCGGCTCACATCAA
GAAGGCGGAGGCGACTACCACAACTACGAGCGCGGGCGCCGAGGCGGCCGAGGGCCAGTTCGACCGCTACTACCACGAAGAGGAGTTGGA
GTCGGCGCTGAGGGAGGCGGCGGCCGCGGGCCTCCCCGGCCTGGCCCGCCTCTTTAGCATCGGCCGCTCGGTGGAAGGCCGGCCGCTGTG
GGTGCTTCGCCTCACCGCCGGCCTGGGGTCGCTAATCCCTGAGGGCGACGCGGGGCCTGACGCTGCCGGGCCCGACGCTGCGGGGCCGCT
GCTGCCCGGCCGGCCCCAGGTGAAGCTGGTGGGCAACATGCATGGCGACGAGACCGTGTCGCGCCAGGTGTTGATCTACTTGGCCCGCGA
GCTGGCGGCCGGCTACCGCCGCGGGGACCCGCGCCTGGTCCGCCTGCTCAACACCACCGACGTGTACCTGCTGCCCAGCCTCAACCCCGA
TGGCTTCGAGCGTGCCCGCGAGGGCGACTGTGGCTTCGGCGACGGCGGCCCGTCCGGGGCCAGCGGCCGCGACAATAGTCGCGGCCGCGA
CCTCAACCGAAGCTTTCCCGACCAGTTTAGCACCGGCGAACCCCCCGCCCTGGACGAGGTGCCCGAGGTGCGCGCCCTCATCGAGTGGAT
CCGCAGGAACAAGTTTGTGCTTTCTGGAAATCTGCATGGTGGCTCAGTGGTAGCAAGCTATCCTTTTGATGATTCTCCAGAACATAAGGC
CACTGGAATCTATAGCAAAACCTCAGATGATGAAGTATTTAAATACTTGGCAAAAGCTTATGCTTCAAACCACCCCATAATGAAAACTGG
TGAGCCTCATTGTCCAGGAGATGAAGACGAGACTTTCAAAGATGGAATCACAAACGGCGCACATTGGTATGATGTGGAAGTGGAGGTGAA
GCCGGTGCTGCCAAGAGCCATGCCCAGTTCCATGGGGGGTGGGGGTGGAGGCAGCCCCAGCCCTGTGGAGCTACGGGGGGCTCTGGTGGG
CTCTGTGGACCCCACACTGCGGGAGCAGCAACTGCAGCAGGAGCTCCTGGCGCTCAAGCAGCAGCAGCAGCTGCAGAAGCAGCTCCTGTT
CGCTGAGTTCCAGAAACAGCATGACCACCTGACAAGGCAGCATGAGGTCCAGCTGCAGAAGCACCTCAAGCAGCAGCAGGAGATGCTGGC
AGCCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCGGCAGCAGGAGCTGGAGCAGCAGCGGCAGCGGGAGCAGCAGCGGCAGGAAGAGCT
GGAGAAGCAGCGGCTGGAGCAGCAGCTGCTCATCCTGCGGAACAAGGAGAAGAGCAAAGAGAGTGCCATTGCCAGCACTGAGGTAAAGCT
GAGGCTCCAGGAATTCCTCTTGTCGAAGTCAAAGGAGCCCACACCAGGCGGCCTCAACCATTCCCTCCCACAGCACCCCAAATGCTGGGG
AGCCCACCATGCTTCTTTGGACCAGAGTTCCCCTCCCCAGAGCGGCCCCCCTGGGACGCCTCCCTCCTACAAACTGCCTTTGCCTGGGCC
CTACGACAGTCGAGACGACTTCCCCCTCCGCAAAACAGCCTCTGAACCCAACTTGAAAGTGCGTTCAAGGCTAAAACAGAAGGTGGCTGA
GCGGAGAAGCAGTCCCCTCCTGCGTCGCAAGGATGGGACTGTTATTAGCACCTTTAAGAAGAGAGCTGTTGAGATCACAGGTGCCGGGCC
TGGGGCGTCGTCCGTGTGTAACAGCGCACCCGGCTCCGGCCCCAGCTCTCCCAACAGCTCCCACAGCACCATCGCTGAGAATGGCTTTAC
TGGCTCAGTCCCCAACATCCCCACTGAGATGCTCCCTCAGCACCGAGCCCTCCCTCTGGACAGCTCCCCCAACCAGTTCAGCCTCTACAC
GTCTCCTTCTCTGCCCAACATCTCCCTAGGGCTGCAGGCCACGGTCACTGTCACCAACTCACACCTCACTGCCTCCCCGAAGCTGTCGAC
ACAGCAGGAGGCCGAGAGGCAGGCCCTCCAGTCCCTGCGGCAGGGTGGCACGCTGACCGGCAAGTTCATGAGCACATCCTCTATTCCTGG
CTGCCTGCTGGGCGTGGCACTGGAGGGCGACGGGAGCCCCCACGGGCATGCCTCCCTGCTGCAGCATGTGCTGTTGCTGGAGCAGGCCCG
GCAGCAGAGCACCCTCATTGCTGTGCCACTCCACGGGCAGTCCCCACTAGTGACGGGTGAACGTGTGGCCACCAGCATGCGGACGGTAGG
CAAGCTCCCGCGGCATCGGCCCCTGAGCCGCACTCAGTCCTCACCGCTGCCGCAGAGTCCCCAGGCCCTGCAGCAGCTGGTCATGCAACA
ACAGCACCAGCAGTTCCTGGAGAAGCAGAAGCAGCAGCAGCTACAGCTGGGCAAGATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCC
CACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGG
CTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAA
GGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCC
GCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGC
CCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTCTACGACACGTTCATGCTAAAGCACCA
GTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAG
CAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAATACCACACCCTGCTCTATGGGACCAG
TCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGG
GGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGT
GGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTT
CAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATGGCAA
TGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGG
GGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGT
GGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGC
TGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGG
GGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGT
AGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAG
CAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGAC
TGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCC
CATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAAAACA
AAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCCTGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGT
GGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTTCCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTT
CCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGCACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGC
CCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGGGGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCA
GCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAGGGGAGGTGGGCACCCACCCTGCGATTCTCCACCCTT
TCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTTGGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCT
GTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTACTTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGT
GGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAACCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCC
CTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGGGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGA
CCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCTCCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGAT
GGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTCGGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTC
CCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGTCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGT
GGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGGGAAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCC
TCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAATCTGTTTACATATTTATTATCCTATGGGGGCCTGAG
CAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAGTGTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGA
TGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTCCCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTC
TGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGTTAAGTATTTTGTAACCCGTTACACTGTGTGTCCTTG

>In-frame_ENST00000225719_ENST00000225983_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(amino acids)=1422AA_start in transcript=76_stop in transcript=4344
MASGRDERPPWRLGRLLLLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYHEEELESALREAAAAGLPGLARLFSIGRSVE
GRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLP
SLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEVPEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDS
PEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEVEVKPVLPRAMPSSMGGGGGGSPSPVELR
GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQ
RQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSPNSSHSTIA
ENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLPQSPQALQQ
LVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTF
MLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLP
CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWD
IHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKV

--------------------------------------------------------------
>In-frame_ENST00000225719_ENST00000393622_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(transcript)=5968nt_BP=1070nt
GGGGATCCGGCGGGCCCCCGCCGCCCGGAGCGCTGAGCCGCGGGAGCGGAGCCGGGGTTAGCGGCGCTGCTGGAAGATGGCGAGCGGCCG
GGACGAGCGGCCGCCTTGGCGGCTAGGGCGGCTCCTGTTGCTCATGTGCCTGCTGCTGCTGGGGAGCTCGGCCCGGGCGGCTCACATCAA
GAAGGCGGAGGCGACTACCACAACTACGAGCGCGGGCGCCGAGGCGGCCGAGGGCCAGTTCGACCGCTACTACCACGAAGAGGAGTTGGA
GTCGGCGCTGAGGGAGGCGGCGGCCGCGGGCCTCCCCGGCCTGGCCCGCCTCTTTAGCATCGGCCGCTCGGTGGAAGGCCGGCCGCTGTG
GGTGCTTCGCCTCACCGCCGGCCTGGGGTCGCTAATCCCTGAGGGCGACGCGGGGCCTGACGCTGCCGGGCCCGACGCTGCGGGGCCGCT
GCTGCCCGGCCGGCCCCAGGTGAAGCTGGTGGGCAACATGCATGGCGACGAGACCGTGTCGCGCCAGGTGTTGATCTACTTGGCCCGCGA
GCTGGCGGCCGGCTACCGCCGCGGGGACCCGCGCCTGGTCCGCCTGCTCAACACCACCGACGTGTACCTGCTGCCCAGCCTCAACCCCGA
TGGCTTCGAGCGTGCCCGCGAGGGCGACTGTGGCTTCGGCGACGGCGGCCCGTCCGGGGCCAGCGGCCGCGACAATAGTCGCGGCCGCGA
CCTCAACCGAAGCTTTCCCGACCAGTTTAGCACCGGCGAACCCCCCGCCCTGGACGAGGTGCCCGAGGTGCGCGCCCTCATCGAGTGGAT
CCGCAGGAACAAGTTTGTGCTTTCTGGAAATCTGCATGGTGGCTCAGTGGTAGCAAGCTATCCTTTTGATGATTCTCCAGAACATAAGGC
CACTGGAATCTATAGCAAAACCTCAGATGATGAAGTATTTAAATACTTGGCAAAAGCTTATGCTTCAAACCACCCCATAATGAAAACTGG
TGAGCCTCATTGTCCAGGAGATGAAGACGAGACTTTCAAAGATGGAATCACAAACGGCGCACATTGGTATGATGTGGAAGTGGAGGTGAA
GCCGGTGCTGCCAAGAGCCATGCCCAGTTCCATGGGGGGTGGGGGTGGAGGCAGCCCCAGCCCTGTGGAGCTACGGGGGGCTCTGGTGGG
CTCTGTGGACCCCACACTGCGGGAGCAGCAACTGCAGCAGGAGCTCCTGGCGCTCAAGCAGCAGCAGCAGCTGCAGAAGCAGCTCCTGTT
CGCTGAGTTCCAGAAACAGCATGACCACCTGACAAGGCAGCATGAGGTCCAGCTGCAGAAGCACCTCAAGCAGCAGCAGGAGATGCTGGC
AGCCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCGGCAGCAGGAGCTGGAGCAGCAGCGGCAGCGGGAGCAGCAGCGGCAGGAAGAGCT
GGAGAAGCAGCGGCTGGAGCAGCAGCTGCTCATCCTGCGGAACAAGGAGAAGAGCAAAGAGAGTGCCATTGCCAGCACTGAGGTAAAGCT
GAGGCTCCAGGAATTCCTCTTGTCGAAGTCAAAGGAGCCCACACCAGGCGGCCTCAACCATTCCCTCCCACAGCACCCCAAATGCTGGGG
AGCCCACCATGCTTCTTTGGACCAGAGTTCCCCTCCCCAGAGCGGCCCCCCTGGGACGCCTCCCTCCTACAAACTGCCTTTGCCTGGGCC
CTACGACAGTCGAGACGACTTCCCCCTCCGCAAAACAGCCTCTGAACCCAACTTGAAAGTGCGTTCAAGGCTAAAACAGAAGGTGGCTGA
GCGGAGAAGCAGTCCCCTCCTGCGTCGCAAGGATGGGACTGTTATTAGCACCTTTAAGAAGAGAGCTGTTGAGATCACAGGTGCCGGGCC
TGGGGCGTCGTCCGTGTGTAACAGCGCACCCGGCTCCGGCCCCAGCTCTCCCAACAGCTCCCACAGCACCATCGCTGAGAATGGCTTTAC
TGGCTCAGTCCCCAACATCCCCACTGAGATGCTCCCTCAGCACCGAGCCCTCCCTCTGGACAGCTCCCCCAACCAGTTCAGCCTCTACAC
GTCTCCTTCTCTGCCCAACATCTCCCTAGGGCTGCAGGCCACGGTCACTGTCACCAACTCACACCTCACTGCCTCCCCGAAGCTGTCGAC
ACAGCAGGAGGCCGAGAGGCAGGCCCTCCAGTCCCTGCGGCAGGGTGGCACGCTGACCGGCAAGTTCATGAGCACATCCTCTATTCCTGG
CTGCCTGCTGGGCGTGGCACTGGAGGGCGACGGGAGCCCCCACGGGCATGCCTCCCTGCTGCAGCATGTGCTGTTGCTGGAGCAGGCCCG
GCAGCAGAGCACCCTCATTGCTGTGCCACTCCACGGGCAGTCCCCACTAGTGACGGGTGAACGTGTGGCCACCAGCATGCGGACGGTAGG
CAAGCTCCCGCGGCATCGGCCCCTGAGCCGCACTCAGTCCTCACCGCTGCCGCAGAGTCCCCAGGCCCTGCAGCAGCTGGTCATGCAACA
ACAGCACCAGCAGTTCCTGGAGAAGCAGAAGCAGCAGCAGCTACAGCTGGGCAAGATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCC
CACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGG
CTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAA
GGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCC
GCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGC
CCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTCTACGACACGTTCATGCTAAAGCACCA
GTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAG
CAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAATACCACACCCTGCTCTATGGGACCAG
TCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGG
GGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGT
GGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTT
CAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATGGCAA
TGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGG
GGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGT
GGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGC
TGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGG
GGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGT
AGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAG
CAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGAC
TGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCC
CATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAAAACA
AAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCCTGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGT
GGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTTCCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTT
CCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGCACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGC
CCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGGGGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCA
GCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAGGGGAGGTGGGCACCCACCCTGCGATTCTCCACCCTT
TCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTTGGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCT
GTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTACTTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGT
GGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAACCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCC
CTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGGGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGA
CCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCTCCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGAT
GGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTCGGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTC
CCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGTCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGT
GGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGGGAAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCC
TCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAATCTGTTTACATATTTATTATCCTATGGGGGCCTGAG
CAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAGTGTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGA
TGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTCCCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTC
TGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGTTAAGTATTTTGTAACCCGTTACACTGTGTGTCCTTG

>In-frame_ENST00000225719_ENST00000393622_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(amino acids)=1422AA_start in transcript=76_stop in transcript=4344
MASGRDERPPWRLGRLLLLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYHEEELESALREAAAAGLPGLARLFSIGRSVE
GRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLP
SLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEVPEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDS
PEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEVEVKPVLPRAMPSSMGGGGGGSPSPVELR
GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQ
RQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSPNSSHSTIA
ENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLPQSPQALQQ
LVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTF
MLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLP
CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWD
IHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKV

--------------------------------------------------------------
>In-frame_ENST00000225719_ENST00000336057_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(transcript)=5712nt_BP=1070nt
GGGGATCCGGCGGGCCCCCGCCGCCCGGAGCGCTGAGCCGCGGGAGCGGAGCCGGGGTTAGCGGCGCTGCTGGAAGATGGCGAGCGGCCG
GGACGAGCGGCCGCCTTGGCGGCTAGGGCGGCTCCTGTTGCTCATGTGCCTGCTGCTGCTGGGGAGCTCGGCCCGGGCGGCTCACATCAA
GAAGGCGGAGGCGACTACCACAACTACGAGCGCGGGCGCCGAGGCGGCCGAGGGCCAGTTCGACCGCTACTACCACGAAGAGGAGTTGGA
GTCGGCGCTGAGGGAGGCGGCGGCCGCGGGCCTCCCCGGCCTGGCCCGCCTCTTTAGCATCGGCCGCTCGGTGGAAGGCCGGCCGCTGTG
GGTGCTTCGCCTCACCGCCGGCCTGGGGTCGCTAATCCCTGAGGGCGACGCGGGGCCTGACGCTGCCGGGCCCGACGCTGCGGGGCCGCT
GCTGCCCGGCCGGCCCCAGGTGAAGCTGGTGGGCAACATGCATGGCGACGAGACCGTGTCGCGCCAGGTGTTGATCTACTTGGCCCGCGA
GCTGGCGGCCGGCTACCGCCGCGGGGACCCGCGCCTGGTCCGCCTGCTCAACACCACCGACGTGTACCTGCTGCCCAGCCTCAACCCCGA
TGGCTTCGAGCGTGCCCGCGAGGGCGACTGTGGCTTCGGCGACGGCGGCCCGTCCGGGGCCAGCGGCCGCGACAATAGTCGCGGCCGCGA
CCTCAACCGAAGCTTTCCCGACCAGTTTAGCACCGGCGAACCCCCCGCCCTGGACGAGGTGCCCGAGGTGCGCGCCCTCATCGAGTGGAT
CCGCAGGAACAAGTTTGTGCTTTCTGGAAATCTGCATGGTGGCTCAGTGGTAGCAAGCTATCCTTTTGATGATTCTCCAGAACATAAGGC
CACTGGAATCTATAGCAAAACCTCAGATGATGAAGTATTTAAATACTTGGCAAAAGCTTATGCTTCAAACCACCCCATAATGAAAACTGG
TGAGCCTCATTGTCCAGGAGATGAAGACGAGACTTTCAAAGATGGAATCACAAACGGCGCACATTGGTATGATGTGGAAGTGGAGGTGAA
GCCGGTGCTGCCAAGAGCCATGCCCAGTTCCATGGGGGGTGGGGGTGGAGGCAGCCCCAGCCCTGTGGAGCTACGGGGGGCTCTGGTGGG
CTCTGTGGACCCCACACTGCGGGAGCAGCAACTGCAGCAGGAGCTCCTGGCGCTCAAGCAGCAGCAGCAGCTGCAGAAGCAGCTCCTGTT
CGCTGAGTTCCAGAAACAGCATGACCACCTGACAAGGCAGCATGAGGTCCAGCTGCAGAAGCACCTCAAGCAGCAGCAGGAGATGCTGGC
AGCCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCGGCAGCAGGAGCTGGAGCAGCAGCGGCAGCGGGAGCAGCAGCGGCAGGAAGAGCT
GGAGAAGCAGCGGCTGGAGCAGCAGCTGCTCATCCTGCGGAACAAGGAGAAGAGCAAAGAGAGTGCCATTGCCAGCACTGAGGTAAAGCT
GAGGCTCCAGGAATTCCTCTTGTCGAAGTCAAAGGAGCCCACACCAGGCGGCCTCAACCATTCCCTCCCACAGCACCCCAAATGCTGGGG
AGCCCACCATGCTTCTTTGGACCAGAGTTCCCCTCCCCAGAGCGGCCCCCCTGGGACGCCTCCCTCCTACAAACTGCCTTTGCCTGGGCC
CTACGACAGTCGAGACGACTTCCCCCTCCGCAAAACAGCCTCTGAACCCAACTTGAAAGTGCGTTCAAGGCTAAAACAGAAGGTGGCTGA
GCGGAGAAGCAGTCCCCTCCTGCGTCGCAAGGATGGGACTGTTATTAGCACCTTTAAGAAGAGAGCTGTTGAGATCACAGGTGCCGGGCC
TGGGGCGTCGTCCGTGTGTAACAGCGCACCCGGCTCCGGCCCCAGCTCTCCCAACAGCTCCCACAGCACCATCGCTGAGAATGGCTTTAC
TGGCTCAGTCCCCAACATCCCCACTGAGATGCTCCCTCAGCACCGAGCCCTCCCTCTGGACAGCTCCCCCAACCAGTTCAGCCTCTACAC
GTCTCCTTCTCTGCCCAACATCTCCCTAGGGCTGCAGGCCACGGTCACTGTCACCAACTCACACCTCACTGCCTCCCCGAAGCTGTCGAC
ACAGCAGGAGGCCGAGAGGCAGGCCCTCCAGTCCCTGCGGCAGGGTGGCACGCTGACCGGCAAGTTCATGAGCACATCCTCTATTCCTGG
CTGCCTGCTGGGCGTGGCACTGGAGGGCGACGGGAGCCCCCACGGGCATGCCTCCCTGCTGCAGCATGTGCTGTTGCTGGAGCAGGCCCG
GCAGCAGAGCACCCTCATTGCTGTGCCACTCCACGGGCAGTCCCCACTAGTGACGGGTGAACGTGTGGCCACCAGCATGCGGACGGTAGG
CAAGCTCCCGCGGCATCGGCCCCTGAGCCGCACTCAGTCCTCACCGCTGCCGCAGAGTCCCCAGGCCCTGCAGCAGCTGGTCATGCAACA
ACAGCACCAGCAGTTCCTGGAGAAGCAGAAGCAGCAGCAGCTACAGCTGGGCAAGATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCC
CACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGG
CTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAA
GGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCC
GCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGC
CCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCC
TTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGA
GCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAGCCAT
GGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGA
CATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGAACTT
CTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGGACCC
CCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTC
CGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCT
GATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTC
GGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGT
CATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGAC
CGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAG
GCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGATTTTGTTTATTT
TTTCTATTAAAAACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCCTGCTCCTCTACGCTGCCTCA
GGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTTCCCAGCCCTGTCCCATGTGT
CCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGCACGGGGGCCCAGACAGTACT
CTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGGGGAAATGCCTTAATTTCACT
CTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAGGGGAGGTGGGCACCCACCCTG
CGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTTGGTCTCAGCACTGATGGGAG
GCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTACTTCCCCTTCCCCGGGGCTGAG
AGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAACCAGGTCTGCTCCCCACCTT
ACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGGGCTCCAGGCTGGTGAGAGCC
CCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCTCCCTCCTGGGGCCTTTTGTT
TTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTCGGCTCTCAGCTGGAGCTTCC
ATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGTCCCTTCTCTTTCCCAGGAGC
CCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGGGAAGTGGCTCCTAGGGGGCTG
ACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAATCTGTTTACATATTTATTATC
CTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAGTGTGCTTGTGTGTTTGTTTTA
GATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTCCCGGCCCCTTACCCACTCTC
TCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGTTAAGTATTTTGTAACCCGTTA

>In-frame_ENST00000225719_ENST00000336057_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(amino acids)=1337AA_start in transcript=76_stop in transcript=4089
MASGRDERPPWRLGRLLLLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYHEEELESALREAAAAGLPGLARLFSIGRSVE
GRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLP
SLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEVPEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDS
PEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEVEVKPVLPRAMPSSMGGGGGGSPSPVELR
GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQ
RQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSPNSSHSTIA
ENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLPQSPQALQQ
LVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGPISQKM
YAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVL
IVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPD
VVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVA

--------------------------------------------------------------
>In-frame_ENST00000225719_ENST00000586802_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(transcript)=4427nt_BP=1070nt
GGGGATCCGGCGGGCCCCCGCCGCCCGGAGCGCTGAGCCGCGGGAGCGGAGCCGGGGTTAGCGGCGCTGCTGGAAGATGGCGAGCGGCCG
GGACGAGCGGCCGCCTTGGCGGCTAGGGCGGCTCCTGTTGCTCATGTGCCTGCTGCTGCTGGGGAGCTCGGCCCGGGCGGCTCACATCAA
GAAGGCGGAGGCGACTACCACAACTACGAGCGCGGGCGCCGAGGCGGCCGAGGGCCAGTTCGACCGCTACTACCACGAAGAGGAGTTGGA
GTCGGCGCTGAGGGAGGCGGCGGCCGCGGGCCTCCCCGGCCTGGCCCGCCTCTTTAGCATCGGCCGCTCGGTGGAAGGCCGGCCGCTGTG
GGTGCTTCGCCTCACCGCCGGCCTGGGGTCGCTAATCCCTGAGGGCGACGCGGGGCCTGACGCTGCCGGGCCCGACGCTGCGGGGCCGCT
GCTGCCCGGCCGGCCCCAGGTGAAGCTGGTGGGCAACATGCATGGCGACGAGACCGTGTCGCGCCAGGTGTTGATCTACTTGGCCCGCGA
GCTGGCGGCCGGCTACCGCCGCGGGGACCCGCGCCTGGTCCGCCTGCTCAACACCACCGACGTGTACCTGCTGCCCAGCCTCAACCCCGA
TGGCTTCGAGCGTGCCCGCGAGGGCGACTGTGGCTTCGGCGACGGCGGCCCGTCCGGGGCCAGCGGCCGCGACAATAGTCGCGGCCGCGA
CCTCAACCGAAGCTTTCCCGACCAGTTTAGCACCGGCGAACCCCCCGCCCTGGACGAGGTGCCCGAGGTGCGCGCCCTCATCGAGTGGAT
CCGCAGGAACAAGTTTGTGCTTTCTGGAAATCTGCATGGTGGCTCAGTGGTAGCAAGCTATCCTTTTGATGATTCTCCAGAACATAAGGC
CACTGGAATCTATAGCAAAACCTCAGATGATGAAGTATTTAAATACTTGGCAAAAGCTTATGCTTCAAACCACCCCATAATGAAAACTGG
TGAGCCTCATTGTCCAGGAGATGAAGACGAGACTTTCAAAGATGGAATCACAAACGGCGCACATTGGTATGATGTGGAAGTGGAGGTGAA
GCCGGTGCTGCCAAGAGCCATGCCCAGTTCCATGGGGGGTGGGGGTGGAGGCAGCCCCAGCCCTGTGGAGCTACGGGGGGCTCTGGTGGG
CTCTGTGGACCCCACACTGCGGGAGCAGCAACTGCAGCAGGAGCTCCTGGCGCTCAAGCAGCAGCAGCAGCTGCAGAAGCAGCTCCTGTT
CGCTGAGTTCCAGAAACAGCATGACCACCTGACAAGGCAGCATGAGGTCCAGCTGCAGAAGCACCTCAAGCAGCAGCAGGAGATGCTGGC
AGCCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCGGCAGCAGGAGCTGGAGCAGCAGCGGCAGCGGGAGCAGCAGCGGCAGGAAGAGCT
GGAGAAGCAGCGGCTGGAGCAGCAGCTGCTCATCCTGCGGAACAAGGAGAAGAGCAAAGAGAGTGCCATTGCCAGCACTGAGGTAAAGCT
GAGGCTCCAGGAATTCCTCTTGTCGAAGTCAAAGGAGCCCACACCAGGCGGCCTCAACCATTCCCTCCCACAGCACCCCAAATGCTGGGG
AGCCCACCATGCTTCTTTGGACCAGAGTTCCCCTCCCCAGAGCGGCCCCCCTGGGACGCCTCCCTCCTACAAACTGCCTTTGCCTGGGCC
CTACGACAGTCGAGACGACTTCCCCCTCCGCAAAACAGCCTCTGAACCCAACTTGAAAGTGCGTTCAAGGCTAAAACAGAAGGTGGCTGA
GCGGAGAAGCAGTCCCCTCCTGCGTCGCAAGGATGGGACTGTTATTAGCACCTTTAAGAAGAGAGCTGTTGAGATCACAGGTGCCGGGCC
TGGGGCGTCGTCCGTGTGTAACAGCGCACCCGGCTCCGGCCCCAGCTCTCCCAACAGCTCCCACAGCACCATCGCTGAGAATGGCTTTAC
TGGCTCAGTCCCCAACATCCCCACTGAGATGCTCCCTCAGCACCGAGCCCTCCCTCTGGACAGCTCCCCCAACCAGTTCAGCCTCTACAC
GTCTCCTTCTCTGCCCAACATCTCCCTAGGGCTGCAGGCCACGGTCACTGTCACCAACTCACACCTCACTGCCTCCCCGAAGCTGTCGAC
ACAGCAGGAGGCCGAGAGGCAGGCCCTCCAGTCCCTGCGGCAGGGTGGCACGCTGACCGGCAAGTTCATGAGCACATCCTCTATTCCTGG
CTGCCTGCTGGGCGTGGCACTGGAGGGCGACGGGAGCCCCCACGGGCATGCCTCCCTGCTGCAGCATGTGCTGTTGCTGGAGCAGGCCCG
GCAGCAGAGCACCCTCATTGCTGTGCCACTCCACGGGCAGTCCCCACTAGTGACGGGTGAACGTGTGGCCACCAGCATGCGGACGGTAGG
CAAGCTCCCGCGGCATCGGCCCCTGAGCCGCACTCAGTCCTCACCGCTGCCGCAGAGTCCCCAGGCCCTGCAGCAGCTGGTCATGCAACA
ACAGCACCAGCAGTTCCTGGAGAAGCAGAAGCAGCAGCAGCTACAGCTGGGCAAGATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCC
CACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGG
CTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAA
GGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCC
GCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGC
CCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTCTACGACACGTTCATGCTAAAGCACCA
GTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAG
CAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAATACCACACCCTGCTCTATGGGACCAG
TCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGG
GGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGT
GGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTT
CAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATGGCAA
TGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGG
GGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGT
GGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGC
TGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGG
GGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGT
AGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAG
CAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGAC
TGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCC
CATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAAAACA

>In-frame_ENST00000225719_ENST00000586802_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(amino acids)=1422AA_start in transcript=76_stop in transcript=4344
MASGRDERPPWRLGRLLLLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYHEEELESALREAAAAGLPGLARLFSIGRSVE
GRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLP
SLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEVPEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDS
PEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEVEVKPVLPRAMPSSMGGGGGGSPSPVELR
GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQ
RQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSPNSSHSTIA
ENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLPQSPQALQQ
LVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTF
MLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLP
CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWD
IHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKV

--------------------------------------------------------------
>In-frame_ENST00000543464_ENST00000225983_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(transcript)=5560nt_BP=655nt
AGTGTGGCTGGGACTTAGAATTAGGCAATCTGATTCCCGATAGTCCTCTTAGCCACGGAGGGACACTGGAGCCCAAAAATGGCAGATGAT
ATTCCCAGGATCTTCCCCTTGCCTATTTGACAGAAGCTGATTTTTCTCCAATTTTTACCTCTGACTCAGCTTAAGAAGATATGGACTTAG
CTGGAGAACTTGCACAGATCTGTGAGCCGCTTCATTTTAGACTCTGAAGGGTTTGTGATGTCATTTGTGCACCTTATTAGCCTGGGCAGA
ATGGCTAATGGTCACACTTCTAATACACACTTTAAGTGTTATTAAGCATTGCATGAGGTTTAAAAAATTACAAAGTAGAAGAAGGAGGAC
CTCAAGAAATTAGTATAAAACAAGAGAATGTTATAAATATTTATGAGGTTTGTGCTTTCTGGAAATCTGCATGGTGGCTCAGTGGTAGCA
AGCTATCCTTTTGATGATTCTCCAGAACATAAGGCCACTGGAATCTATAGCAAAACCTCAGATGATGAAGTATTTAAATACTTGGCAAAA
GCTTATGCTTCAAACCACCCCATAATGAAAACTGGTGAGCCTCATTGTCCAGGAGATGAAGACGAGACTTTCAAAGATGGAATCACAAAC
GGCGCACATTGGTATGATGTGGAAGTGGAGGTGAAGCCGGTGCTGCCAAGAGCCATGCCCAGTTCCATGGGGGGTGGGGGTGGAGGCAGC
CCCAGCCCTGTGGAGCTACGGGGGGCTCTGGTGGGCTCTGTGGACCCCACACTGCGGGAGCAGCAACTGCAGCAGGAGCTCCTGGCGCTC
AAGCAGCAGCAGCAGCTGCAGAAGCAGCTCCTGTTCGCTGAGTTCCAGAAACAGCATGACCACCTGACAAGGCAGCATGAGGTCCAGCTG
CAGAAGCACCTCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCGGCAGCAGGAGCTGGAGCAG
CAGCGGCAGCGGGAGCAGCAGCGGCAGGAAGAGCTGGAGAAGCAGCGGCTGGAGCAGCAGCTGCTCATCCTGCGGAACAAGGAGAAGAGC
AAAGAGAGTGCCATTGCCAGCACTGAGGTAAAGCTGAGGCTCCAGGAATTCCTCTTGTCGAAGTCAAAGGAGCCCACACCAGGCGGCCTC
AACCATTCCCTCCCACAGCACCCCAAATGCTGGGGAGCCCACCATGCTTCTTTGGACCAGAGTTCCCCTCCCCAGAGCGGCCCCCCTGGG
ACGCCTCCCTCCTACAAACTGCCTTTGCCTGGGCCCTACGACAGTCGAGACGACTTCCCCCTCCGCAAAACAGCCTCTGAACCCAACTTG
AAAGTGCGTTCAAGGCTAAAACAGAAGGTGGCTGAGCGGAGAAGCAGTCCCCTCCTGCGTCGCAAGGATGGGACTGTTATTAGCACCTTT
AAGAAGAGAGCTGTTGAGATCACAGGTGCCGGGCCTGGGGCGTCGTCCGTGTGTAACAGCGCACCCGGCTCCGGCCCCAGCTCTCCCAAC
AGCTCCCACAGCACCATCGCTGAGAATGGCTTTACTGGCTCAGTCCCCAACATCCCCACTGAGATGCTCCCTCAGCACCGAGCCCTCCCT
CTGGACAGCTCCCCCAACCAGTTCAGCCTCTACACGTCTCCTTCTCTGCCCAACATCTCCCTAGGGCTGCAGGCCACGGTCACTGTCACC
AACTCACACCTCACTGCCTCCCCGAAGCTGTCGACACAGCAGGAGGCCGAGAGGCAGGCCCTCCAGTCCCTGCGGCAGGGTGGCACGCTG
ACCGGCAAGTTCATGAGCACATCCTCTATTCCTGGCTGCCTGCTGGGCGTGGCACTGGAGGGCGACGGGAGCCCCCACGGGCATGCCTCC
CTGCTGCAGCATGTGCTGTTGCTGGAGCAGGCCCGGCAGCAGAGCACCCTCATTGCTGTGCCACTCCACGGGCAGTCCCCACTAGTGACG
GGTGAACGTGTGGCCACCAGCATGCGGACGGTAGGCAAGCTCCCGCGGCATCGGCCCCTGAGCCGCACTCAGTCCTCACCGCTGCCGCAG
AGTCCCCAGGCCCTGCAGCAGCTGGTCATGCAACAACAGCACCAGCAGTTCCTGGAGAAGCAGAAGCAGCAGCAGCTACAGCTGGGCAAG
ATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTG
CTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGAC
GATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGT
GCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCAC
CAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACA
GGTGTGGTCTACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGC
ATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTG
CACTCTGAATACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAG
AAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATG
GCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCAC
GCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAG
GTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCAT
CGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCA
TGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCA
CCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTT
GGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGAT
GCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCA
GTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGA
GAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCA
GCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCAC
CATTGTGATTTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCC
TGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTT
CCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGC
ACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGG
GGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAGG
GGAGGTGGGCACCCACCCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTT
GGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTACT
TCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAA
CCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGG
GCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCT
CCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTC
GGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGT
CCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGGG
AAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAAT
CTGTTTACATATTTATTATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAGT
GTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTC
CCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGTT

>In-frame_ENST00000543464_ENST00000225983_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(amino acids)=1175AA_start in transcript=402_stop in transcript=3929
MRFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEVEVKPV
LPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAK
QQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAH
HASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGA
SSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQ
EAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKL
PRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGST
ESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPG
GMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPL
NRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNS
VAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEY
LTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVEL
QPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPME

--------------------------------------------------------------
>In-frame_ENST00000543464_ENST00000393622_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(transcript)=5553nt_BP=655nt
AGTGTGGCTGGGACTTAGAATTAGGCAATCTGATTCCCGATAGTCCTCTTAGCCACGGAGGGACACTGGAGCCCAAAAATGGCAGATGAT
ATTCCCAGGATCTTCCCCTTGCCTATTTGACAGAAGCTGATTTTTCTCCAATTTTTACCTCTGACTCAGCTTAAGAAGATATGGACTTAG
CTGGAGAACTTGCACAGATCTGTGAGCCGCTTCATTTTAGACTCTGAAGGGTTTGTGATGTCATTTGTGCACCTTATTAGCCTGGGCAGA
ATGGCTAATGGTCACACTTCTAATACACACTTTAAGTGTTATTAAGCATTGCATGAGGTTTAAAAAATTACAAAGTAGAAGAAGGAGGAC
CTCAAGAAATTAGTATAAAACAAGAGAATGTTATAAATATTTATGAGGTTTGTGCTTTCTGGAAATCTGCATGGTGGCTCAGTGGTAGCA
AGCTATCCTTTTGATGATTCTCCAGAACATAAGGCCACTGGAATCTATAGCAAAACCTCAGATGATGAAGTATTTAAATACTTGGCAAAA
GCTTATGCTTCAAACCACCCCATAATGAAAACTGGTGAGCCTCATTGTCCAGGAGATGAAGACGAGACTTTCAAAGATGGAATCACAAAC
GGCGCACATTGGTATGATGTGGAAGTGGAGGTGAAGCCGGTGCTGCCAAGAGCCATGCCCAGTTCCATGGGGGGTGGGGGTGGAGGCAGC
CCCAGCCCTGTGGAGCTACGGGGGGCTCTGGTGGGCTCTGTGGACCCCACACTGCGGGAGCAGCAACTGCAGCAGGAGCTCCTGGCGCTC
AAGCAGCAGCAGCAGCTGCAGAAGCAGCTCCTGTTCGCTGAGTTCCAGAAACAGCATGACCACCTGACAAGGCAGCATGAGGTCCAGCTG
CAGAAGCACCTCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCGGCAGCAGGAGCTGGAGCAG
CAGCGGCAGCGGGAGCAGCAGCGGCAGGAAGAGCTGGAGAAGCAGCGGCTGGAGCAGCAGCTGCTCATCCTGCGGAACAAGGAGAAGAGC
AAAGAGAGTGCCATTGCCAGCACTGAGGTAAAGCTGAGGCTCCAGGAATTCCTCTTGTCGAAGTCAAAGGAGCCCACACCAGGCGGCCTC
AACCATTCCCTCCCACAGCACCCCAAATGCTGGGGAGCCCACCATGCTTCTTTGGACCAGAGTTCCCCTCCCCAGAGCGGCCCCCCTGGG
ACGCCTCCCTCCTACAAACTGCCTTTGCCTGGGCCCTACGACAGTCGAGACGACTTCCCCCTCCGCAAAACAGCCTCTGAACCCAACTTG
AAAGTGCGTTCAAGGCTAAAACAGAAGGTGGCTGAGCGGAGAAGCAGTCCCCTCCTGCGTCGCAAGGATGGGACTGTTATTAGCACCTTT
AAGAAGAGAGCTGTTGAGATCACAGGTGCCGGGCCTGGGGCGTCGTCCGTGTGTAACAGCGCACCCGGCTCCGGCCCCAGCTCTCCCAAC
AGCTCCCACAGCACCATCGCTGAGAATGGCTTTACTGGCTCAGTCCCCAACATCCCCACTGAGATGCTCCCTCAGCACCGAGCCCTCCCT
CTGGACAGCTCCCCCAACCAGTTCAGCCTCTACACGTCTCCTTCTCTGCCCAACATCTCCCTAGGGCTGCAGGCCACGGTCACTGTCACC
AACTCACACCTCACTGCCTCCCCGAAGCTGTCGACACAGCAGGAGGCCGAGAGGCAGGCCCTCCAGTCCCTGCGGCAGGGTGGCACGCTG
ACCGGCAAGTTCATGAGCACATCCTCTATTCCTGGCTGCCTGCTGGGCGTGGCACTGGAGGGCGACGGGAGCCCCCACGGGCATGCCTCC
CTGCTGCAGCATGTGCTGTTGCTGGAGCAGGCCCGGCAGCAGAGCACCCTCATTGCTGTGCCACTCCACGGGCAGTCCCCACTAGTGACG
GGTGAACGTGTGGCCACCAGCATGCGGACGGTAGGCAAGCTCCCGCGGCATCGGCCCCTGAGCCGCACTCAGTCCTCACCGCTGCCGCAG
AGTCCCCAGGCCCTGCAGCAGCTGGTCATGCAACAACAGCACCAGCAGTTCCTGGAGAAGCAGAAGCAGCAGCAGCTACAGCTGGGCAAG
ATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTG
CTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGAC
GATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGT
GCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCAC
CAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACA
GGTGTGGTCTACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGC
ATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTG
CACTCTGAATACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAG
AAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATG
GCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCAC
GCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAG
GTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCAT
CGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCA
TGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCA
CCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTT
GGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGAT
GCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCA
GTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGA
GAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCA
GCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCAC
CATTGTGATTTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCC
TGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTT
CCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGC
ACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGG
GGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAGG
GGAGGTGGGCACCCACCCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTT
GGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTACT
TCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAA
CCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGG
GCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCT
CCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTC
GGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGT
CCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGGG
AAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAAT
CTGTTTACATATTTATTATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAGT
GTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTC
CCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGTT

>In-frame_ENST00000543464_ENST00000393622_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(amino acids)=1175AA_start in transcript=402_stop in transcript=3929
MRFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEVEVKPV
LPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAK
QQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAH
HASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGA
SSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQ
EAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKL
PRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGST
ESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPG
GMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPL
NRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNS
VAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEY
LTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVEL
QPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPME

--------------------------------------------------------------
>In-frame_ENST00000543464_ENST00000336057_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(transcript)=5297nt_BP=655nt
AGTGTGGCTGGGACTTAGAATTAGGCAATCTGATTCCCGATAGTCCTCTTAGCCACGGAGGGACACTGGAGCCCAAAAATGGCAGATGAT
ATTCCCAGGATCTTCCCCTTGCCTATTTGACAGAAGCTGATTTTTCTCCAATTTTTACCTCTGACTCAGCTTAAGAAGATATGGACTTAG
CTGGAGAACTTGCACAGATCTGTGAGCCGCTTCATTTTAGACTCTGAAGGGTTTGTGATGTCATTTGTGCACCTTATTAGCCTGGGCAGA
ATGGCTAATGGTCACACTTCTAATACACACTTTAAGTGTTATTAAGCATTGCATGAGGTTTAAAAAATTACAAAGTAGAAGAAGGAGGAC
CTCAAGAAATTAGTATAAAACAAGAGAATGTTATAAATATTTATGAGGTTTGTGCTTTCTGGAAATCTGCATGGTGGCTCAGTGGTAGCA
AGCTATCCTTTTGATGATTCTCCAGAACATAAGGCCACTGGAATCTATAGCAAAACCTCAGATGATGAAGTATTTAAATACTTGGCAAAA
GCTTATGCTTCAAACCACCCCATAATGAAAACTGGTGAGCCTCATTGTCCAGGAGATGAAGACGAGACTTTCAAAGATGGAATCACAAAC
GGCGCACATTGGTATGATGTGGAAGTGGAGGTGAAGCCGGTGCTGCCAAGAGCCATGCCCAGTTCCATGGGGGGTGGGGGTGGAGGCAGC
CCCAGCCCTGTGGAGCTACGGGGGGCTCTGGTGGGCTCTGTGGACCCCACACTGCGGGAGCAGCAACTGCAGCAGGAGCTCCTGGCGCTC
AAGCAGCAGCAGCAGCTGCAGAAGCAGCTCCTGTTCGCTGAGTTCCAGAAACAGCATGACCACCTGACAAGGCAGCATGAGGTCCAGCTG
CAGAAGCACCTCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCGGCAGCAGGAGCTGGAGCAG
CAGCGGCAGCGGGAGCAGCAGCGGCAGGAAGAGCTGGAGAAGCAGCGGCTGGAGCAGCAGCTGCTCATCCTGCGGAACAAGGAGAAGAGC
AAAGAGAGTGCCATTGCCAGCACTGAGGTAAAGCTGAGGCTCCAGGAATTCCTCTTGTCGAAGTCAAAGGAGCCCACACCAGGCGGCCTC
AACCATTCCCTCCCACAGCACCCCAAATGCTGGGGAGCCCACCATGCTTCTTTGGACCAGAGTTCCCCTCCCCAGAGCGGCCCCCCTGGG
ACGCCTCCCTCCTACAAACTGCCTTTGCCTGGGCCCTACGACAGTCGAGACGACTTCCCCCTCCGCAAAACAGCCTCTGAACCCAACTTG
AAAGTGCGTTCAAGGCTAAAACAGAAGGTGGCTGAGCGGAGAAGCAGTCCCCTCCTGCGTCGCAAGGATGGGACTGTTATTAGCACCTTT
AAGAAGAGAGCTGTTGAGATCACAGGTGCCGGGCCTGGGGCGTCGTCCGTGTGTAACAGCGCACCCGGCTCCGGCCCCAGCTCTCCCAAC
AGCTCCCACAGCACCATCGCTGAGAATGGCTTTACTGGCTCAGTCCCCAACATCCCCACTGAGATGCTCCCTCAGCACCGAGCCCTCCCT
CTGGACAGCTCCCCCAACCAGTTCAGCCTCTACACGTCTCCTTCTCTGCCCAACATCTCCCTAGGGCTGCAGGCCACGGTCACTGTCACC
AACTCACACCTCACTGCCTCCCCGAAGCTGTCGACACAGCAGGAGGCCGAGAGGCAGGCCCTCCAGTCCCTGCGGCAGGGTGGCACGCTG
ACCGGCAAGTTCATGAGCACATCCTCTATTCCTGGCTGCCTGCTGGGCGTGGCACTGGAGGGCGACGGGAGCCCCCACGGGCATGCCTCC
CTGCTGCAGCATGTGCTGTTGCTGGAGCAGGCCCGGCAGCAGAGCACCCTCATTGCTGTGCCACTCCACGGGCAGTCCCCACTAGTGACG
GGTGAACGTGTGGCCACCAGCATGCGGACGGTAGGCAAGCTCCCGCGGCATCGGCCCCTGAGCCGCACTCAGTCCTCACCGCTGCCGCAG
AGTCCCCAGGCCCTGCAGCAGCTGGTCATGCAACAACAGCACCAGCAGTTCCTGGAGAAGCAGAAGCAGCAGCAGCTACAGCTGGGCAAG
ATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTG
CTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGAC
GATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGT
GCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCAC
CAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACA
GGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCC
AGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGG
CCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAG
TTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTC
TACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTAC
AATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATT
GCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTC
ACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTG
ACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAG
CCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTG
GGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAG
GCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCAT
CCCTCTGGGCTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCT
CAGCCTTGCCCCTCCTGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGG
GGGTGGTGGTGTCTTCCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGC
CAGCTCAAGGTGGGCACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTT
TCAGCTGATTTGGGGGGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAA
GATGCAGAGTGGAGGGGAGGTGGGCACCCACCCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTC
CTCCTCCTTCCTCTTGGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACAC
TCCTCACAGCCTACTTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCA
GGAGGAGTAACAGAACCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGT
GGTCCCTGCAGAGGGGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGG
GGCAGAGGCTCACCTCCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCC
AGGGATCCAGGAGTCGGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAG
GGGGCTGGGCGCTGTCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAG
GAAACCAAAGATGGGAAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTC
CAGGGCCCCACCAATCTGTTTACATATTTATTATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCA
CCATCGGTTCATAGTGTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTG
CTGAGCCCCAGGCTCCCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGG

>In-frame_ENST00000543464_ENST00000336057_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(amino acids)=1090AA_start in transcript=402_stop in transcript=3674
MRFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEVEVKPV
LPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAK
QQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAH
HASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGA
SSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQ
EAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKL
PRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGST
ESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPG
GMKSPPDQPVKHLFTTGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGF
CFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPI
GDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSAL
LSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAAAAREHSPRPA

--------------------------------------------------------------
>In-frame_ENST00000543464_ENST00000586802_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(transcript)=4012nt_BP=655nt
AGTGTGGCTGGGACTTAGAATTAGGCAATCTGATTCCCGATAGTCCTCTTAGCCACGGAGGGACACTGGAGCCCAAAAATGGCAGATGAT
ATTCCCAGGATCTTCCCCTTGCCTATTTGACAGAAGCTGATTTTTCTCCAATTTTTACCTCTGACTCAGCTTAAGAAGATATGGACTTAG
CTGGAGAACTTGCACAGATCTGTGAGCCGCTTCATTTTAGACTCTGAAGGGTTTGTGATGTCATTTGTGCACCTTATTAGCCTGGGCAGA
ATGGCTAATGGTCACACTTCTAATACACACTTTAAGTGTTATTAAGCATTGCATGAGGTTTAAAAAATTACAAAGTAGAAGAAGGAGGAC
CTCAAGAAATTAGTATAAAACAAGAGAATGTTATAAATATTTATGAGGTTTGTGCTTTCTGGAAATCTGCATGGTGGCTCAGTGGTAGCA
AGCTATCCTTTTGATGATTCTCCAGAACATAAGGCCACTGGAATCTATAGCAAAACCTCAGATGATGAAGTATTTAAATACTTGGCAAAA
GCTTATGCTTCAAACCACCCCATAATGAAAACTGGTGAGCCTCATTGTCCAGGAGATGAAGACGAGACTTTCAAAGATGGAATCACAAAC
GGCGCACATTGGTATGATGTGGAAGTGGAGGTGAAGCCGGTGCTGCCAAGAGCCATGCCCAGTTCCATGGGGGGTGGGGGTGGAGGCAGC
CCCAGCCCTGTGGAGCTACGGGGGGCTCTGGTGGGCTCTGTGGACCCCACACTGCGGGAGCAGCAACTGCAGCAGGAGCTCCTGGCGCTC
AAGCAGCAGCAGCAGCTGCAGAAGCAGCTCCTGTTCGCTGAGTTCCAGAAACAGCATGACCACCTGACAAGGCAGCATGAGGTCCAGCTG
CAGAAGCACCTCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCAGCAGCAGGAGATGCTGGCAGCCAAGCGGCAGCAGGAGCTGGAGCAG
CAGCGGCAGCGGGAGCAGCAGCGGCAGGAAGAGCTGGAGAAGCAGCGGCTGGAGCAGCAGCTGCTCATCCTGCGGAACAAGGAGAAGAGC
AAAGAGAGTGCCATTGCCAGCACTGAGGTAAAGCTGAGGCTCCAGGAATTCCTCTTGTCGAAGTCAAAGGAGCCCACACCAGGCGGCCTC
AACCATTCCCTCCCACAGCACCCCAAATGCTGGGGAGCCCACCATGCTTCTTTGGACCAGAGTTCCCCTCCCCAGAGCGGCCCCCCTGGG
ACGCCTCCCTCCTACAAACTGCCTTTGCCTGGGCCCTACGACAGTCGAGACGACTTCCCCCTCCGCAAAACAGCCTCTGAACCCAACTTG
AAAGTGCGTTCAAGGCTAAAACAGAAGGTGGCTGAGCGGAGAAGCAGTCCCCTCCTGCGTCGCAAGGATGGGACTGTTATTAGCACCTTT
AAGAAGAGAGCTGTTGAGATCACAGGTGCCGGGCCTGGGGCGTCGTCCGTGTGTAACAGCGCACCCGGCTCCGGCCCCAGCTCTCCCAAC
AGCTCCCACAGCACCATCGCTGAGAATGGCTTTACTGGCTCAGTCCCCAACATCCCCACTGAGATGCTCCCTCAGCACCGAGCCCTCCCT
CTGGACAGCTCCCCCAACCAGTTCAGCCTCTACACGTCTCCTTCTCTGCCCAACATCTCCCTAGGGCTGCAGGCCACGGTCACTGTCACC
AACTCACACCTCACTGCCTCCCCGAAGCTGTCGACACAGCAGGAGGCCGAGAGGCAGGCCCTCCAGTCCCTGCGGCAGGGTGGCACGCTG
ACCGGCAAGTTCATGAGCACATCCTCTATTCCTGGCTGCCTGCTGGGCGTGGCACTGGAGGGCGACGGGAGCCCCCACGGGCATGCCTCC
CTGCTGCAGCATGTGCTGTTGCTGGAGCAGGCCCGGCAGCAGAGCACCCTCATTGCTGTGCCACTCCACGGGCAGTCCCCACTAGTGACG
GGTGAACGTGTGGCCACCAGCATGCGGACGGTAGGCAAGCTCCCGCGGCATCGGCCCCTGAGCCGCACTCAGTCCTCACCGCTGCCGCAG
AGTCCCCAGGCCCTGCAGCAGCTGGTCATGCAACAACAGCACCAGCAGTTCCTGGAGAAGCAGAAGCAGCAGCAGCTACAGCTGGGCAAG
ATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTG
CTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGAC
GATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGT
GCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCAC
CAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACA
GGTGTGGTCTACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGC
ATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTG
CACTCTGAATACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAG
AAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATG
GCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCAC
GCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAG
GTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCAT
CGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCA
TGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCA
CCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTT
GGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGAT
GCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCA
GTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGA
GAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCA
GCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCAC

>In-frame_ENST00000543464_ENST00000586802_TCGA-J4-A67T-01A_CPD_chr17_28712254_+_HDAC5_chr17_42171202_length(amino acids)=1175AA_start in transcript=402_stop in transcript=3929
MRFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEVEVKPV
LPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAK
QQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAH
HASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGA
SSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQ
EAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKL
PRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGST
ESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPG
GMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPL
NRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNS
VAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEY
LTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVEL
QPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPME

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CPD-HDAC5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CPD-HDAC5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CPD-HDAC5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneHDAC5C0011570Mental Depression2PSYGENET
TgeneHDAC5C0011581Depressive disorder2PSYGENET
TgeneHDAC5C0001546Adjustment Disorders1CTD_human
TgeneHDAC5C0005586Bipolar Disorder1CTD_human
TgeneHDAC5C0005587Depression, Bipolar1CTD_human
TgeneHDAC5C0009171Cocaine Abuse1CTD_human
TgeneHDAC5C0011579Reactive depression1CTD_human
TgeneHDAC5C0024713Manic Disorder1CTD_human
TgeneHDAC5C0029456Osteoporosis1GENOMICS_ENGLAND
TgeneHDAC5C0036421Systemic Scleroderma1CTD_human
TgeneHDAC5C0041696Unipolar Depression1PSYGENET
TgeneHDAC5C0236736Cocaine-Related Disorders1CTD_human
TgeneHDAC5C0338831Manic1CTD_human
TgeneHDAC5C0340543Familial primary pulmonary hypertension1CTD_human
TgeneHDAC5C0600427Cocaine Dependence1CTD_human
TgeneHDAC5C1269683Major Depressive Disorder1PSYGENET
TgeneHDAC5C1522512Transient Situational Disturbance1CTD_human
TgeneHDAC5C1969342PULMONARY HYPERTENSION, PRIMARY, DEXFENFLURAMINE-ASSOCIATED1CTD_human
TgeneHDAC5C1969343Pulmonary Hypertension, Primary, Fenfluramine-Associated1CTD_human
TgeneHDAC5C3203102Idiopathic pulmonary arterial hypertension1CTD_human
TgeneHDAC5C3714844Pulmonary Hypertension, Primary, 1, With Hereditary Hemorrhagic Telangiectasia1CTD_human
TgeneHDAC5C4552070Pulmonary Hypertension, Primary, 11CTD_human