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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CTNNB1-FGF12 (FusionGDB2 ID:20319)

Fusion Gene Summary for CTNNB1-FGF12

check button Fusion gene summary
Fusion gene informationFusion gene name: CTNNB1-FGF12
Fusion gene ID: 20319
HgeneTgene
Gene symbol

CTNNB1

FGF12

Gene ID

1499

2257

Gene namecatenin beta 1fibroblast growth factor 12
SynonymsCTNNB|EVR7|MRD19|NEDSDV|armadilloEIEE47|FGF12B|FHF1
Cytomap

3p22.1

3q28-q29

Type of geneprotein-codingprotein-coding
Descriptioncatenin beta-1catenin (cadherin-associated protein), beta 1, 88kDafibroblast growth factor 12fibroblast growth factor 12Bfibroblast growth factor FGF-12bfibroblast growth factor homologous factor 1myocyte-activating factor
Modification date2020032720200315
UniProtAcc

P35222

P61328

Ensembl transtripts involved in fusion geneENST00000471014, ENST00000405570, 
ENST00000396183, ENST00000349496, 
ENST00000453024, ENST00000396185, 
ENST00000445105, ENST00000264730, 
ENST00000454309, ENST00000450716, 
ENST00000430714, ENST00000466144, 
Fusion gene scores* DoF score19 X 14 X 13=345812 X 7 X 9=756
# samples 2114
** MAII scorelog2(21/3458*10)=-4.04147663597616
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/756*10)=-2.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CTNNB1 [Title/Abstract] AND FGF12 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTNNB1(41241161)-FGF12(192078327), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCTNNB1

GO:0000209

protein polyubiquitination

29374064

HgeneCTNNB1

GO:0008285

negative regulation of cell proliferation

12970740

HgeneCTNNB1

GO:0030997

regulation of centriole-centriole cohesion

18086858

HgeneCTNNB1

GO:0032355

response to estradiol

15304487

HgeneCTNNB1

GO:0033234

negative regulation of protein sumoylation

22155184

HgeneCTNNB1

GO:0043065

positive regulation of apoptotic process

12651860|12970740

HgeneCTNNB1

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

29374064

HgeneCTNNB1

GO:0043525

positive regulation of neuron apoptotic process

19591802

HgeneCTNNB1

GO:0045893

positive regulation of transcription, DNA-templated

12970740|18787224

HgeneCTNNB1

GO:0045944

positive regulation of transcription by RNA polymerase II

9065402|11751639|12651860|14660579|18193033

HgeneCTNNB1

GO:0060070

canonical Wnt signaling pathway

10644691|12937339|19187541

HgeneCTNNB1

GO:0071681

cellular response to indole-3-methanol

10868478

HgeneCTNNB1

GO:0090279

regulation of calcium ion import

19996314

HgeneCTNNB1

GO:1904798

positive regulation of core promoter binding

22723415

HgeneCTNNB1

GO:2000008

regulation of protein localization to cell surface

19996314


check buttonFusion gene breakpoints across CTNNB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across FGF12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCECTCGA-AJ-A2QKCTNNB1chr3

41241161

+FGF12chr3

192078327

-
ChimerDB4UCECTCGA-AJ-A2QK-01ACTNNB1chr3

41241161

+FGF12chr3

192078327

-


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Fusion Gene ORF analysis for CTNNB1-FGF12

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000471014ENST00000445105CTNNB1chr3

41241161

+FGF12chr3

192078327

-
intron-3CDSENST00000471014ENST00000264730CTNNB1chr3

41241161

+FGF12chr3

192078327

-
intron-3CDSENST00000471014ENST00000454309CTNNB1chr3

41241161

+FGF12chr3

192078327

-
intron-3CDSENST00000471014ENST00000450716CTNNB1chr3

41241161

+FGF12chr3

192078327

-
intron-intronENST00000471014ENST00000430714CTNNB1chr3

41241161

+FGF12chr3

192078327

-
intron-intronENST00000471014ENST00000466144CTNNB1chr3

41241161

+FGF12chr3

192078327

-
intron-3CDSENST00000405570ENST00000445105CTNNB1chr3

41241161

+FGF12chr3

192078327

-
intron-3CDSENST00000405570ENST00000264730CTNNB1chr3

41241161

+FGF12chr3

192078327

-
intron-3CDSENST00000405570ENST00000454309CTNNB1chr3

41241161

+FGF12chr3

192078327

-
intron-3CDSENST00000405570ENST00000450716CTNNB1chr3

41241161

+FGF12chr3

192078327

-
intron-intronENST00000405570ENST00000430714CTNNB1chr3

41241161

+FGF12chr3

192078327

-
intron-intronENST00000405570ENST00000466144CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000396183ENST00000445105CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000396183ENST00000264730CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000396183ENST00000454309CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000396183ENST00000450716CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-intronENST00000396183ENST00000430714CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-intronENST00000396183ENST00000466144CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000349496ENST00000445105CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000349496ENST00000264730CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000349496ENST00000454309CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000349496ENST00000450716CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-intronENST00000349496ENST00000430714CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-intronENST00000349496ENST00000466144CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000453024ENST00000445105CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000453024ENST00000264730CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000453024ENST00000454309CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000453024ENST00000450716CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-intronENST00000453024ENST00000430714CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-intronENST00000453024ENST00000466144CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000396185ENST00000445105CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000396185ENST00000264730CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000396185ENST00000454309CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-3CDSENST00000396185ENST00000450716CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-intronENST00000396185ENST00000430714CTNNB1chr3

41241161

+FGF12chr3

192078327

-
5UTR-intronENST00000396185ENST00000466144CTNNB1chr3

41241161

+FGF12chr3

192078327

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for CTNNB1-FGF12


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CTNNB1-FGF12


check button Go to

FGviewer for the breakpoints of :-:

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CTNNB1

P35222

FGF12

P61328

FUNCTION: Key downstream component of the canonical Wnt signaling pathway (PubMed:17524503, PubMed:18077326, PubMed:18086858, PubMed:18957423, PubMed:21262353, PubMed:22155184, PubMed:22647378, PubMed:22699938). In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome (PubMed:17524503, PubMed:18077326, PubMed:18086858, PubMed:18957423, PubMed:21262353, PubMed:22155184, PubMed:22647378, PubMed:22699938). In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (PubMed:17524503, PubMed:18077326, PubMed:18086858, PubMed:18957423, PubMed:21262353, PubMed:22155184, PubMed:22647378, PubMed:22699938). Involved in the regulation of cell adhesion, as component of an E-cadherin:catenin adhesion complex (By similarity). Acts as a negative regulator of centrosome cohesion (PubMed:18086858). Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization (PubMed:21262353). Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2 (PubMed:18957423). Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML (PubMed:22155184). Promotes neurogenesis by maintaining sympathetic neuroblasts within the cell cycle (By similarity). Involved in chondrocyte differentiation via interaction with SOX9: SOX9-binding competes with the binding sites of TCF/LEF within CTNNB1, thereby inhibiting the Wnt signaling (By similarity). {ECO:0000250|UniProtKB:Q02248, ECO:0000269|PubMed:17524503, ECO:0000269|PubMed:18077326, ECO:0000269|PubMed:18086858, ECO:0000269|PubMed:18957423, ECO:0000269|PubMed:21262353, ECO:0000269|PubMed:22155184, ECO:0000269|PubMed:22647378, ECO:0000269|PubMed:22699938}.FUNCTION: Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation. {ECO:0000269|PubMed:27164707}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for CTNNB1-FGF12


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for CTNNB1-FGF12


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CTNNB1-FGF12


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneCTNNB1P35222DB03904UreaSmall moleculeApproved|Investigational
HgeneCTNNB1P35222DB03904UreaSmall moleculeApproved|Investigational
HgeneCTNNB1P35222DB03904UreaSmall moleculeApproved|Investigational
HgeneCTNNB1P35222DB03904UreaSmall moleculeApproved|Investigational

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Related Diseases for CTNNB1-FGF12


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCTNNB1C0007102Malignant tumor of colon9CTD_human
HgeneCTNNB1C0009375Colonic Neoplasms9CTD_human
HgeneCTNNB1C3554449MENTAL RETARDATION, AUTOSOMAL DOMINANT 196CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneCTNNB1C0009402Colorectal Carcinoma5CTD_human;UNIPROT
HgeneCTNNB1C2239176Liver carcinoma5CGI;CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneCTNNB1C0009404Colorectal Neoplasms4CTD_human
HgeneCTNNB1C0001418Adenocarcinoma3CTD_human
HgeneCTNNB1C0019207Hepatoma, Morris3CTD_human
HgeneCTNNB1C0019208Hepatoma, Novikoff3CTD_human
HgeneCTNNB1C0023904Liver Neoplasms, Experimental3CTD_human
HgeneCTNNB1C0086404Experimental Hepatoma3CTD_human
HgeneCTNNB1C0205641Adenocarcinoma, Basal Cell3CTD_human
HgeneCTNNB1C0205642Adenocarcinoma, Oxyphilic3CTD_human
HgeneCTNNB1C0205643Carcinoma, Cribriform3CTD_human
HgeneCTNNB1C0205644Carcinoma, Granular Cell3CTD_human
HgeneCTNNB1C0205645Adenocarcinoma, Tubular3CTD_human
HgeneCTNNB1C0206711Pilomatrixoma3CTD_human;ORPHANET;UNIPROT
HgeneCTNNB1C1879526Aberrant Crypt Foci3CTD_human
HgeneCTNNB1C0001430Adenoma2CTD_human
HgeneCTNNB1C0006142Malignant neoplasm of breast2CTD_human
HgeneCTNNB1C0023903Liver neoplasms2CTD_human
HgeneCTNNB1C0025149Medulloblastoma2CGI;CTD_human;UNIPROT
HgeneCTNNB1C0027626Neoplasm Invasiveness2CTD_human
HgeneCTNNB1C0027708Nephroblastoma2CTD_human
HgeneCTNNB1C0033578Prostatic Neoplasms2CTD_human
HgeneCTNNB1C0036341Schizophrenia2PSYGENET
HgeneCTNNB1C0205646Adenoma, Basal Cell2CTD_human
HgeneCTNNB1C0205647Follicular adenoma2CTD_human
HgeneCTNNB1C0205648Adenoma, Microcystic2CTD_human
HgeneCTNNB1C0205649Adenoma, Monomorphic2CTD_human
HgeneCTNNB1C0205650Papillary adenoma2CTD_human
HgeneCTNNB1C0205651Adenoma, Trabecular2CTD_human
HgeneCTNNB1C0235874Disease Exacerbation2CTD_human
HgeneCTNNB1C0345904Malignant neoplasm of liver2CTD_human
HgeneCTNNB1C0376358Malignant neoplasm of prostate2CTD_human
HgeneCTNNB1C0678222Breast Carcinoma2CTD_human
HgeneCTNNB1C1140680Malignant neoplasm of ovary2CGI;CTD_human;UNIPROT
HgeneCTNNB1C1257931Mammary Neoplasms, Human2CTD_human
HgeneCTNNB1C1458155Mammary Neoplasms2CTD_human
HgeneCTNNB1C2930471Bilateral Wilms Tumor2CTD_human
HgeneCTNNB1C4539767EXUDATIVE VITREORETINOPATHY 72GENOMICS_ENGLAND;UNIPROT
HgeneCTNNB1C4704874Mammary Carcinoma, Human2CTD_human
HgeneCTNNB1C0000772Multiple congenital anomalies1CTD_human
HgeneCTNNB1C0001624Adrenal Gland Neoplasms1CTD_human
HgeneCTNNB1C0007193Cardiomyopathy, Dilated1CTD_human
HgeneCTNNB1C0007528Cecal Neoplasms1CTD_human
HgeneCTNNB1C0007621Neoplastic Cell Transformation1CTD_human
HgeneCTNNB1C0007873Uterine Cervical Neoplasm1CTD_human
HgeneCTNNB1C0010276Craniopharyngioma1CTD_human;ORPHANET
HgeneCTNNB1C0014518Toxic Epidermal Necrolysis1CTD_human
HgeneCTNNB1C0016059Fibrosis1CTD_human
HgeneCTNNB1C0018923Hemangiosarcoma1CTD_human
HgeneCTNNB1C0019193Hepatitis, Toxic1CTD_human
HgeneCTNNB1C0021841Intestinal Neoplasms1CTD_human
HgeneCTNNB1C0023890Liver Cirrhosis1CTD_human
HgeneCTNNB1C0024121Lung Neoplasms1CTD_human
HgeneCTNNB1C0026846Muscular Atrophy1CTD_human
HgeneCTNNB1C0027627Neoplasm Metastasis1CTD_human
HgeneCTNNB1C0027746Nerve Degeneration1CTD_human
HgeneCTNNB1C0030297Pancreatic Neoplasm1CTD_human
HgeneCTNNB1C0031149Peritoneal Neoplasms1CTD_human
HgeneCTNNB1C0038325Stevens-Johnson Syndrome1CTD_human
HgeneCTNNB1C0149721Left Ventricular Hypertrophy1CTD_human
HgeneCTNNB1C0151744Myocardial Ischemia1CTD_human
HgeneCTNNB1C0153437Malignant neoplasm of cecum1CTD_human
HgeneCTNNB1C0206624Hepatoblastoma1CGI;CTD_human
HgeneCTNNB1C0206669Hepatocellular Adenoma1CTD_human
HgeneCTNNB1C0206686Adrenocortical carcinoma1CTD_human
HgeneCTNNB1C0232347No-Reflow Phenomenon1CTD_human
HgeneCTNNB1C0239946Fibrosis, Liver1CTD_human
HgeneCTNNB1C0242379Malignant neoplasm of lung1CTD_human
HgeneCTNNB1C0242698Ventricular Dysfunction, Left1CTD_human
HgeneCTNNB1C0270948Neurogenic Muscular Atrophy1CTD_human
HgeneCTNNB1C0278875Adult Craniopharyngioma1CTD_human
HgeneCTNNB1C0279606Childhood Hepatocellular Carcinoma1ORPHANET
HgeneCTNNB1C0279607Adult Hepatocellular Carcinoma1ORPHANET
HgeneCTNNB1C0334634Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse1CTD_human
HgeneCTNNB1C0339539Familial Exudative Vitreoretinopathy1ORPHANET
HgeneCTNNB1C0342649Vascular calcification1CTD_human
HgeneCTNNB1C0345967Malignant mesothelioma1CTD_human
HgeneCTNNB1C0346627Intestinal Cancer1CTD_human
HgeneCTNNB1C0346647Malignant neoplasm of pancreas1CTD_human
HgeneCTNNB1C0346990Carcinomatosis of peritoneal cavity1CTD_human
HgeneCTNNB1C0376634Craniofacial Abnormalities1CTD_human
HgeneCTNNB1C0431128Papillary craniopharyngioma1CTD_human
HgeneCTNNB1C0431129Adamantinous Craniopharyngioma1CTD_human
HgeneCTNNB1C0431350Primary microcephaly1GENOMICS_ENGLAND
HgeneCTNNB1C0600519Ventricular Remodeling1CTD_human
HgeneCTNNB1C0600520Left Ventricle Remodeling1CTD_human
HgeneCTNNB1C0750887Adrenal Cancer1CTD_human
HgeneCTNNB1C0751061Craniopharyngioma, Child1CTD_human
HgeneCTNNB1C0751958Lymphoma, Lymphocytic, Intermediate1CTD_human
HgeneCTNNB1C0860207Drug-Induced Liver Disease1CTD_human
HgeneCTNNB1C0919267ovarian neoplasm1CGI;CTD_human
HgeneCTNNB1C1262760Hepatitis, Drug-Induced1CTD_human
HgeneCTNNB1C1274933Drug-Induced Stevens Johnson Syndrome1CTD_human
HgeneCTNNB1C1449563Cardiomyopathy, Familial Idiopathic1CTD_human
HgeneCTNNB1C1535926Neurodevelopmental Disorders1CTD_human
HgeneCTNNB1C1623038Cirrhosis1CTD_human
HgeneCTNNB1C1851402Exudative vitreoretinopathy 11ORPHANET
HgeneCTNNB1C2713615Slow-Flow Phenomenon1CTD_human
HgeneCTNNB1C3658290Drug-Induced Acute Liver Injury1CTD_human
HgeneCTNNB1C3658301Mycoplasma-Induced Stevens-Johnson Syndrome1CTD_human
HgeneCTNNB1C3658302Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum1CTD_human
HgeneCTNNB1C4048328cervical cancer1CTD_human
HgeneCTNNB1C4277682Chemical and Drug Induced Liver Injury1CTD_human
HgeneCTNNB1C4279912Chemically-Induced Liver Toxicity1CTD_human
TgeneFGF12C4310685EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 473CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneFGF12C0019209Hepatomegaly1CTD_human
TgeneFGF12C0543888Epileptic encephalopathy1GENOMICS_ENGLAND