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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CYTH1-IL16 (FusionGDB2 ID:21133)

Fusion Gene Summary for CYTH1-IL16

check button Fusion gene summary
Fusion gene informationFusion gene name: CYTH1-IL16
Fusion gene ID: 21133
HgeneTgene
Gene symbol

CYTH1

IL16

Gene ID

9267

3603

Gene namecytohesin 1interleukin 16
SynonymsB2-1|CYTOHESIN-1|D17S811E|PSCD1|SEC7LCF|NIL16|PRIL16|prIL-16
Cytomap

17q25.3

15q25.1

Type of geneprotein-codingprotein-coding
Descriptioncytohesin-1PH, SEC7 and coiled-coil domain-containing protein 1SEC7 homolog B2-1cytoadhesin 1homolog of secretory protein SEC7pleckstrin homology, Sec7 and coiled-coil domains 1pro-interleukin-16lymphocyte chemoattractant factorneuronal interleukin 16prointerleukin 16
Modification date2020031320200313
UniProtAcc

Q15438

.
Ensembl transtripts involved in fusion geneENST00000585509, ENST00000589297, 
ENST00000591455, ENST00000446868, 
ENST00000361101, ENST00000589296, 
ENST00000586175, 		ENST00000394660, 
ENST00000302987, ENST00000394652, 
ENST00000560230, 
Fusion gene scores* DoF score18 X 13 X 7=16382 X 2 X 2=8
# samples 192
** MAII scorelog2(19/1638*10)=-3.10786403331006
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: CYTH1 [Title/Abstract] AND IL16 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCYTH1(76778283)-IL16(81598248), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCYTH1

GO:0030155

regulation of cell adhesion

12606567

TgeneIL16

GO:0051924

regulation of calcium ion transport

24942581


check buttonFusion gene breakpoints across CYTH1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across IL16 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-8243CYTH1chr17

76778283

-IL16chr15

81598248

+


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Fusion Gene ORF analysis for CYTH1-IL16

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000585509ENST00000394660CYTH1chr17

76778283

-IL16chr15

81598248

+
intron-3CDSENST00000585509ENST00000302987CYTH1chr17

76778283

-IL16chr15

81598248

+
intron-3CDSENST00000585509ENST00000394652CYTH1chr17

76778283

-IL16chr15

81598248

+
intron-intronENST00000585509ENST00000560230CYTH1chr17

76778283

-IL16chr15

81598248

+
intron-3CDSENST00000589297ENST00000394660CYTH1chr17

76778283

-IL16chr15

81598248

+
intron-3CDSENST00000589297ENST00000302987CYTH1chr17

76778283

-IL16chr15

81598248

+
intron-3CDSENST00000589297ENST00000394652CYTH1chr17

76778283

-IL16chr15

81598248

+
intron-intronENST00000589297ENST00000560230CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000591455ENST00000394660CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000591455ENST00000302987CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000591455ENST00000394652CYTH1chr17

76778283

-IL16chr15

81598248

+
5CDS-intronENST00000591455ENST00000560230CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000446868ENST00000394660CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000446868ENST00000302987CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000446868ENST00000394652CYTH1chr17

76778283

-IL16chr15

81598248

+
5CDS-intronENST00000446868ENST00000560230CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000361101ENST00000394660CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000361101ENST00000302987CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000361101ENST00000394652CYTH1chr17

76778283

-IL16chr15

81598248

+
5CDS-intronENST00000361101ENST00000560230CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000589296ENST00000394660CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000589296ENST00000302987CYTH1chr17

76778283

-IL16chr15

81598248

+
In-frameENST00000589296ENST00000394652CYTH1chr17

76778283

-IL16chr15

81598248

+
5CDS-intronENST00000589296ENST00000560230CYTH1chr17

76778283

-IL16chr15

81598248

+
intron-3CDSENST00000586175ENST00000394660CYTH1chr17

76778283

-IL16chr15

81598248

+
intron-3CDSENST00000586175ENST00000302987CYTH1chr17

76778283

-IL16chr15

81598248

+
intron-3CDSENST00000586175ENST00000394652CYTH1chr17

76778283

-IL16chr15

81598248

+
intron-intronENST00000586175ENST00000560230CYTH1chr17

76778283

-IL16chr15

81598248

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000591455CYTH1chr1776778283-ENST00000394660IL16chr1581598248+4612719201513197
ENST00000591455CYTH1chr1776778283-ENST00000302987IL16chr1581598248+6507195649185
ENST00000591455CYTH1chr1776778283-ENST00000394652IL16chr1581598248+9357195649184
ENST00000446868CYTH1chr1776778283-ENST00000394660IL16chr1581598248+4634939421535197
ENST00000446868CYTH1chr1776778283-ENST00000302987IL16chr1581598248+67293117671184
ENST00000446868CYTH1chr1776778283-ENST00000394652IL16chr1581598248+95793117671184
ENST00000361101CYTH1chr1776778283-ENST00000394660IL16chr1581598248+4634939421535197
ENST00000361101CYTH1chr1776778283-ENST00000302987IL16chr1581598248+67293117671184
ENST00000361101CYTH1chr1776778283-ENST00000394652IL16chr1581598248+95793117671184
ENST00000589296CYTH1chr1776778283-ENST00000394660IL16chr1581598248+4637969451538197
ENST00000589296CYTH1chr1776778283-ENST00000302987IL16chr1581598248+67596120674184
ENST00000589296CYTH1chr1776778283-ENST00000394652IL16chr1581598248+96096120674184

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000591455ENST00000394660CYTH1chr1776778283-IL16chr1581598248+0.26519260.73480743
ENST00000591455ENST00000302987CYTH1chr1776778283-IL16chr1581598248+0.0068011160.9931988
ENST00000591455ENST00000394652CYTH1chr1776778283-IL16chr1581598248+0.0107949540.989205
ENST00000446868ENST00000394660CYTH1chr1776778283-IL16chr1581598248+0.272298460.72770154
ENST00000446868ENST00000302987CYTH1chr1776778283-IL16chr1581598248+0.007493550.99250644
ENST00000446868ENST00000394652CYTH1chr1776778283-IL16chr1581598248+0.0116710760.98832893
ENST00000361101ENST00000394660CYTH1chr1776778283-IL16chr1581598248+0.272298460.72770154
ENST00000361101ENST00000302987CYTH1chr1776778283-IL16chr1581598248+0.007493550.99250644
ENST00000361101ENST00000394652CYTH1chr1776778283-IL16chr1581598248+0.0116710760.98832893
ENST00000589296ENST00000394660CYTH1chr1776778283-IL16chr1581598248+0.270618980.729381
ENST00000589296ENST00000302987CYTH1chr1776778283-IL16chr1581598248+0.0079342540.9920657
ENST00000589296ENST00000394652CYTH1chr1776778283-IL16chr1581598248+0.0117913030.98820865

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Fusion Genomic Features for CYTH1-IL16


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CYTH1chr1776778283-IL16chr1581598248+9.20E-080.9999999
CYTH1chr1776778283-IL16chr1581598248+9.20E-080.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CYTH1-IL16


check button Go to

FGviewer for the breakpoints of chr17:76778283-chr15:81598248

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CYTH1

Q15438

.
FUNCTION: Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity. {ECO:0000250|UniProtKB:Q9QX11, ECO:0000269|PubMed:10652308, ECO:0000269|PubMed:29420262, ECO:0000269|PubMed:9653114}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneIL16chr17:76778283chr15:81598248ENST0000030298714181234_13191140.01333.0DomainPDZ 4
TgeneIL16chr17:76778283chr15:81598248ENST00000394652371112_1197439.0632.0DomainPDZ 3
TgeneIL16chr17:76778283chr15:81598248ENST00000394652371234_1319439.0632.0DomainPDZ 4
TgeneIL16chr17:76778283chr15:81598248ENST0000039466015191234_13191140.01332.0DomainPDZ 4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCYTH1chr17:76778283chr15:81598248ENST00000361101-11310_677.333333333333333399.0Coiled coilOntology_term=ECO:0000255
HgeneCYTH1chr17:76778283chr15:81598248ENST00000446868-11410_677.333333333333333399.0Coiled coilOntology_term=ECO:0000255
HgeneCYTH1chr17:76778283chr15:81598248ENST00000591455-11310_677.333333333333333398.0Coiled coilOntology_term=ECO:0000255
HgeneCYTH1chr17:76778283chr15:81598248ENST00000361101-113260_3777.333333333333333399.0DomainPH
HgeneCYTH1chr17:76778283chr15:81598248ENST00000361101-11373_2027.333333333333333399.0DomainSEC7
HgeneCYTH1chr17:76778283chr15:81598248ENST00000446868-114260_3777.333333333333333399.0DomainPH
HgeneCYTH1chr17:76778283chr15:81598248ENST00000446868-11473_2027.333333333333333399.0DomainSEC7
HgeneCYTH1chr17:76778283chr15:81598248ENST00000591455-113260_3777.333333333333333398.0DomainPH
HgeneCYTH1chr17:76778283chr15:81598248ENST00000591455-11373_2027.333333333333333398.0DomainSEC7
HgeneCYTH1chr17:76778283chr15:81598248ENST00000361101-113269_2777.333333333333333399.0RegionPhosphatidylinositol 3%2C4%2C5-trisphosphate binding
HgeneCYTH1chr17:76778283chr15:81598248ENST00000361101-113388_3967.333333333333333399.0RegionC-terminal autoinhibitory region
HgeneCYTH1chr17:76778283chr15:81598248ENST00000446868-114269_2777.333333333333333399.0RegionPhosphatidylinositol 3%2C4%2C5-trisphosphate binding
HgeneCYTH1chr17:76778283chr15:81598248ENST00000446868-114388_3967.333333333333333399.0RegionC-terminal autoinhibitory region
HgeneCYTH1chr17:76778283chr15:81598248ENST00000591455-113269_2777.333333333333333398.0RegionPhosphatidylinositol 3%2C4%2C5-trisphosphate binding
HgeneCYTH1chr17:76778283chr15:81598248ENST00000591455-113388_3967.333333333333333398.0RegionC-terminal autoinhibitory region
TgeneIL16chr17:76778283chr15:81598248ENST0000030298714181112_11971140.01333.0DomainPDZ 3
TgeneIL16chr17:76778283chr15:81598248ENST000003029871418216_3021140.01333.0DomainPDZ 1
TgeneIL16chr17:76778283chr15:81598248ENST000003029871418355_4401140.01333.0DomainPDZ 2
TgeneIL16chr17:76778283chr15:81598248ENST0000039465237216_302439.0632.0DomainPDZ 1
TgeneIL16chr17:76778283chr15:81598248ENST0000039465237355_440439.0632.0DomainPDZ 2
TgeneIL16chr17:76778283chr15:81598248ENST0000039466015191112_11971140.01332.0DomainPDZ 3
TgeneIL16chr17:76778283chr15:81598248ENST000003946601519216_3021140.01332.0DomainPDZ 1
TgeneIL16chr17:76778283chr15:81598248ENST000003946601519355_4401140.01332.0DomainPDZ 2


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Fusion Gene Sequence for CYTH1-IL16


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000591455_ENST00000394660_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=4612nt_BP=71nt
CGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACAGCTACGGTTCACAGAGTGTTTCCAA
ATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAGTCTCTCAAGGGGACCACGCACCATG
ATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACTCCAGAGGCCATGCCCGACCTCA
ACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGAGGCCACAGTCTGCACGGTGACACTGG
AGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAGCCTCTCACCATTAACAGGATTTTCA
AAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGTGGCACTGCCATGCAGGGCCTCACACGGT
TTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAAAGCCTCCAGTCCAAGGAAACCACAG
CTGCTGGAGACTCCTAGGCAGGACATGCTGAAGCCAAAGCCAATAACACACAGCTAACACACAGCTCCCATAACCGCTGATTCTCAGGGT
CTCTGCTGCCGCCCCACCCAGATGGGGGAAAGCACAGGTGGGCTTCCCAGTGGCTGCTGCCCAGGCCCAGACCTTCTAGGACGCCACCCA
GCAAAAGGTTGTTCCTAAAATAAGGGCAGAGTCACACGGGGGCAGCTGATACAAATTGCAGACTGTGTAAAAAGAGAGCTTAATGATAAT
ATTGTGGTGCCACAAATAAAATGGATTTATTAGAATTTCATATGACATTCATGCCTGGCTTCGCAAAATGTTTCAAGTACTGTAACTGTG
TCATGATTCACCCCCAAACAGTGACATTTATTTTTCTCATGAATCTGCAATGTGGGCAGAGATTGGAATGGGCAGCTCATCTCTGTCCCA
CTTGGCATCAGCTGGCGTCATGCAAAGTCATGCAAAGGCTGGGACCACGTGAGATCATTCACTCATACATCTGGCCGTTGATGTTGGCTG
GGAACTCACCTGGGGCTGCTGGCCTGAATGCTTATAGGTGGCCTCTCCTTGTGGCCTGGGCCTCCTCACAACATGGTGTCTGGATTCCCA
GGATGAGCATCCCAGGATCGCAAGAGCCATGTAGAAGCTGCATCTTGTTTATACCTTTGCCTTGGAAGTTGCATGGCATCACCTCCACCA
TACTCCATCAGTTAGAGCTGACACAAACCTGCCTGGGTTTAAGGGGAGAGGAAATATTGCTGGGGTCATTTATGAAAAATACAGTTTGTC
ACATGAAACATTTGCAAAATTGTTTTTGGTTGGATTGGAGAAGTAATCCTAGGGAAGGGTGGTGGAGCCAGTAAACAGAGGAGTACAGGT
GAAGCACCAAGCTCAAAGCGTGGACAGGTGTGCCGACAGAAGGAACCAGCGTGTATATGAGGGTATCAAATAAAATTGCTACTACTTACC
TACCACATGCCAAGCACTGTGCTCAGGGCTAAACGGGCATTGCCTTTAGTGATCACAGCAGCTTCTACGGTGTATGGTTCTGTGCCAATG
TATTGATAAGAGGGCACACACTGTGTACAGTAAATGGCTTATCCAGCTGGTGAGTGATGCGGCAGATTGAGTTTTCTTCTGTGATTCGGT
GGAGACTATCAGCCCAAGATGCTTTAAGTGCACAACATTACAGGGAATGCCTGAGTGCCTGGCCAAAGGGATATTTGGTTTGGCCATCTC
TGGATGCCTGATTGCCAAGCTCAGGACCAGGCAATGTGACTTTGCATCAGCAACAACCAGCATCCCTTGACCAGGCCTGGGCCAGAGTAT
TGGTCTCCTCTCAGCCCCTGATCCTGTGAAGTAAGGATGTGGGGGAAGACCTGGCAAGGACACAGATGAAACACAAACAATAGTAATTCT
CAGGCCATCATCAGTGGAGCCATGTTAATGTAATCTGATGGCTTCTCCAGGGTCCACAGGAAGTGAAGAATCTGTTTCCCAGCAGTGGAC
TCAAAACCCATCTGGGCTCCTAACCTTCCTGTAAACCCCTTTAGTGGCTTCATTAGAGCAGGCGTTCAGCTCACTGTTCTATTCATCTCA
AGGAATAATGGGCTTAGAGCAGTTTCTGTCCTGCTGGTTAACTTGTTTGGCCTATTCCATTCTGGATTTTGTCAAGCAGTAGACAAGCAA
TTAGACAAGAACTTGGAGGCACCATTTGTATCCACTTTTTAGACTTAATAGAAACATTGAAGATGAACATAATCTACCAACGAAAGACGT
GATTCAATTCAACACTCCCTTCCCATGACCCAGGCTGGGCAAGGAGGCCACGTGATGTGGAGGGCACATTCCTTGCCTGCACAAACTCAC
CATCTGTGCACGCAGTGGCCTTCCCTAAAATCAGGGAATTGTTTTAAGTCTTATCAAGCAGCCAAGGGATGAAAGAGAAGGTGGGTTTTC
ATCAAGACTGGAAGGTGGGGACAGGGATGAGCATGGAGCTGGCCGTGGGCCTGGGGTACCAAGAGACTCCTTGAGAGACCAGGCAAAGCA
AGTGATTGGGACAGAGGTTATCTGTCCCAGGTTATCTGGGCATAGATGCAGGTGAGCCCATGGCCCTCCCAGTACCTCCTGTCTCTGGCC
TGTTTTAGAAGGTTCTCTCCTCCCCAAGGAGACACAACAACTCCTAGGGCCACTGAAGATATAACTATTGCCCAGGTTTCTGGTCTCTAG
GCTGGGGAAGTCCTCTGGGTAGGAATCAGCAAGAAGATCCTAAAACAAAAGCTCATCCATTTGCGTTCCATGATGCTGGGATTTACACTT
GAGGCTTAGCTTTGCTCTGCCAACTTCTTCAGAGCTGACACAGGATGAAGGCAATGCCATCCTCAAACACTGCAGGCATCACAGCTAACA
ATTGTGAAGTCGTCTTAACTCACCATAAAAAGGAATCCACTCCCAGGCAGCCCTACTTCTTTGCTTTGCCCAGCATTTTACTGATTCATA
CATTATCTCACTTGTGCCAACACTCAAGAAGCAGGCTACACTGACACTGGTATTCCTGCCTCCATATTTTCTTTAAAAGACAAATCAAAG
CAGATATATTAAGTGACTGTTCAAGAGCACACTTGGCCCAAGTGGCAGAGCTTGGACTGGATGCATGTTTTCCAGCTCCTCATCCAGGGC
TCTGACCAGTTTAACCTGATGCAGTCACGTGGAGGAGCAGTGCAGGCACAGTATGTCCCATAGGCCCAGTGAGATGCATTCTTGGTTGGC
TGGCCTTCCACTTGGCTACACAGGGATGTACAAGGCGATCCCATCTTGATAAGACCACCACCTCAGAGTATGGAGCTCAGAGAGGGCAGG
CATGAAGTTTCCTTGGCTGGTGCACCTAGAATTGGCTGAACTCATGAGAAGTTGATATAGAACAGTGCTTGCCACAGAGCGGGGACTCGG
TAAGCACTTAATGAATGAATGAATTCTAAGTCAATCCAAGAGTCTGATGATTTCTTGAAAAGGGTGTTAGCTAAAGGATCTTAGGCATGA
CTGTAGAATTTGTAGTTGCAATAGAACAGAGAAAGAGGAAGCTTTCTGTCTCCTTAACACTGAGCTGTCATGTTTTAAAGCTTGCTCACA
TCTTGGCACATTTAAGAGACAGTCACCCCAGGACTCAAAAATAGGGAAGTAACAGTAACGCAGGGGAAACGTTTTCTGTTTGGAGGAGCA
AAGGCTGAGAACACTGTGAAAACATTTTGCGCGCACAATAGTAACCTGGGTAAATGCAGCGTGAAGGGATTTTAGTCACACGTGGTCTTT
CTTACAAGGAAGGTGGTGGGGGTGCAGATGAGGTTGCTAGAGAATGTTAGAGGATCCCTCTCTGGATTGGAGATAGGGAAAGAAAGTTGC
ACGGCTGCTGAGGCCCCTTCTAGGTGGCAAGGCTGTGCTCCCTGGTTCTGATGATGTGCCTGGGTGGACATGGCCCCTGTGAGTTTGTAC
AGTCTTGCAGCAGGATCTAGAGGGGGGATTTCCAGCCAGGGCTGCTAGACGGAGGCCTACTCTTCCATCTTTCCTGATGGCAGGATGGCC
TGGCCAGGGCCTGGAAGACAGAGACCTCCTGCCTCCGCCTCAGTAAGACGACAAGGAAAGGCAAATGCCCAAGGGAAAGAAAAGGAAGGC
TCTTCTCCCCAGAGTTCCCCATGCAGACATGAGTGCGTGCTCAGTTCAGAATCACTTCTGAGAACTCATCCCTAATGCTGCAGATTTGGG
CTGGAACAGATTCACACTGTCTGGTTTCACCGAGGACATGAAACTCCACCTTGCGGGGATAAAGAGAGAAAAACAAATTCATCAAATGGA
AGACACATTGAAAGTGTTTTTCCTTAATGCTTATCCTGTTTTTAAACCATTATTTCCAAGTTGACACCTTTTTTAAGGAAAAATAAATAT

>In-frame_ENST00000591455_ENST00000394660_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=197AA_start in transcript=920_stop in transcript=1513
MDLLEFHMTFMPGFAKCFKYCNCVMIHPQTVTFIFLMNLQCGQRLEWAAHLCPTWHQLASCKVMQRLGPREIIHSYIWPLMLAGNSPGAA
GLNAYRWPLLVAWASSQHGVWIPRMSIPGSQEPCRSCILFIPLPWKLHGITSTILHQLELTQTCLGLRGEEILLGSFMKNTVCHMKHLQN

--------------------------------------------------------------
>In-frame_ENST00000591455_ENST00000302987_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=650nt_BP=71nt
CGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACAGCTACGGTTCACAGAGTGTTTCCAA
ATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAGTCTCTCAAGGGGACCACGCACCATG
ATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACTCCAGAGGCCATGCCCGACCTCA
ACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGCAGAGGCCACAGTCTGCACGGTGACAC
TGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAGCCTCTCACCATTAACAGGATTT
TCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGTGGCACTGCCATGCAGGGCCTCACAC
GGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAAAGCCTCCAGTCCAAGGAAACCA

>In-frame_ENST00000591455_ENST00000302987_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=185AA_start in transcript=95_stop in transcript=649
MASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLE
KMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTA

--------------------------------------------------------------
>In-frame_ENST00000591455_ENST00000394652_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=935nt_BP=71nt
CGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACAGCTACGGTTCACAGAGTGTTTCCAA
ATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAGTCTCTCAAGGGGACCACGCACCATG
ATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACTCCAGAGGCCATGCCCGACCTCA
ACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGCAGAGGCCACAGTCTGCACGGTGACAC
TGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAGCCTCTCACCATTAACAGGATTT
TCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGTGGCACTGCCATGCAGGGCCTCACAC
GGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAAAGCCTCCAGTCCAAGGAAACCA
CAGCTGCTGGAGACTCCTAGGCAGGACATGCTGAAGCCAAAGCCAATAACACACAGCTAACACACAGCTCCCATAACCGCTGATTCTCAG
GGTCTCTGCTGCCGCCCCACCCAGATGGGGGAAAGCACAGGTGGGCTTCCCAGTGGCTGCTGCCCAGGCCCAGACCTTCTAGGACGCCAC
CCAGCAAAAGGTTGTTCCTAAAATAAGGGCAGAGTCACACGGGGGCAGCTGATACAAATTGCAGACTGTGTAAAAAGAGAGCTTAATGAT

>In-frame_ENST00000591455_ENST00000394652_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=184AA_start in transcript=95_stop in transcript=649
MASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLE
KMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTA

--------------------------------------------------------------
>In-frame_ENST00000446868_ENST00000394660_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=4634nt_BP=93nt
GCGAGCGGGGGCGCGGGTGGCGCGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACAGCT
ACGGTTCACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAGTCT
CTCAAGGGGACCACGCACCATGATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACT
CCAGAGGCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGAGGCC
ACAGTCTGCACGGTGACACTGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAGCCT
CTCACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGTGGCACT
GCCATGCAGGGCCTCACACGGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAAAGC
CTCCAGTCCAAGGAAACCACAGCTGCTGGAGACTCCTAGGCAGGACATGCTGAAGCCAAAGCCAATAACACACAGCTAACACACAGCTCC
CATAACCGCTGATTCTCAGGGTCTCTGCTGCCGCCCCACCCAGATGGGGGAAAGCACAGGTGGGCTTCCCAGTGGCTGCTGCCCAGGCCC
AGACCTTCTAGGACGCCACCCAGCAAAAGGTTGTTCCTAAAATAAGGGCAGAGTCACACGGGGGCAGCTGATACAAATTGCAGACTGTGT
AAAAAGAGAGCTTAATGATAATATTGTGGTGCCACAAATAAAATGGATTTATTAGAATTTCATATGACATTCATGCCTGGCTTCGCAAAA
TGTTTCAAGTACTGTAACTGTGTCATGATTCACCCCCAAACAGTGACATTTATTTTTCTCATGAATCTGCAATGTGGGCAGAGATTGGAA
TGGGCAGCTCATCTCTGTCCCACTTGGCATCAGCTGGCGTCATGCAAAGTCATGCAAAGGCTGGGACCACGTGAGATCATTCACTCATAC
ATCTGGCCGTTGATGTTGGCTGGGAACTCACCTGGGGCTGCTGGCCTGAATGCTTATAGGTGGCCTCTCCTTGTGGCCTGGGCCTCCTCA
CAACATGGTGTCTGGATTCCCAGGATGAGCATCCCAGGATCGCAAGAGCCATGTAGAAGCTGCATCTTGTTTATACCTTTGCCTTGGAAG
TTGCATGGCATCACCTCCACCATACTCCATCAGTTAGAGCTGACACAAACCTGCCTGGGTTTAAGGGGAGAGGAAATATTGCTGGGGTCA
TTTATGAAAAATACAGTTTGTCACATGAAACATTTGCAAAATTGTTTTTGGTTGGATTGGAGAAGTAATCCTAGGGAAGGGTGGTGGAGC
CAGTAAACAGAGGAGTACAGGTGAAGCACCAAGCTCAAAGCGTGGACAGGTGTGCCGACAGAAGGAACCAGCGTGTATATGAGGGTATCA
AATAAAATTGCTACTACTTACCTACCACATGCCAAGCACTGTGCTCAGGGCTAAACGGGCATTGCCTTTAGTGATCACAGCAGCTTCTAC
GGTGTATGGTTCTGTGCCAATGTATTGATAAGAGGGCACACACTGTGTACAGTAAATGGCTTATCCAGCTGGTGAGTGATGCGGCAGATT
GAGTTTTCTTCTGTGATTCGGTGGAGACTATCAGCCCAAGATGCTTTAAGTGCACAACATTACAGGGAATGCCTGAGTGCCTGGCCAAAG
GGATATTTGGTTTGGCCATCTCTGGATGCCTGATTGCCAAGCTCAGGACCAGGCAATGTGACTTTGCATCAGCAACAACCAGCATCCCTT
GACCAGGCCTGGGCCAGAGTATTGGTCTCCTCTCAGCCCCTGATCCTGTGAAGTAAGGATGTGGGGGAAGACCTGGCAAGGACACAGATG
AAACACAAACAATAGTAATTCTCAGGCCATCATCAGTGGAGCCATGTTAATGTAATCTGATGGCTTCTCCAGGGTCCACAGGAAGTGAAG
AATCTGTTTCCCAGCAGTGGACTCAAAACCCATCTGGGCTCCTAACCTTCCTGTAAACCCCTTTAGTGGCTTCATTAGAGCAGGCGTTCA
GCTCACTGTTCTATTCATCTCAAGGAATAATGGGCTTAGAGCAGTTTCTGTCCTGCTGGTTAACTTGTTTGGCCTATTCCATTCTGGATT
TTGTCAAGCAGTAGACAAGCAATTAGACAAGAACTTGGAGGCACCATTTGTATCCACTTTTTAGACTTAATAGAAACATTGAAGATGAAC
ATAATCTACCAACGAAAGACGTGATTCAATTCAACACTCCCTTCCCATGACCCAGGCTGGGCAAGGAGGCCACGTGATGTGGAGGGCACA
TTCCTTGCCTGCACAAACTCACCATCTGTGCACGCAGTGGCCTTCCCTAAAATCAGGGAATTGTTTTAAGTCTTATCAAGCAGCCAAGGG
ATGAAAGAGAAGGTGGGTTTTCATCAAGACTGGAAGGTGGGGACAGGGATGAGCATGGAGCTGGCCGTGGGCCTGGGGTACCAAGAGACT
CCTTGAGAGACCAGGCAAAGCAAGTGATTGGGACAGAGGTTATCTGTCCCAGGTTATCTGGGCATAGATGCAGGTGAGCCCATGGCCCTC
CCAGTACCTCCTGTCTCTGGCCTGTTTTAGAAGGTTCTCTCCTCCCCAAGGAGACACAACAACTCCTAGGGCCACTGAAGATATAACTAT
TGCCCAGGTTTCTGGTCTCTAGGCTGGGGAAGTCCTCTGGGTAGGAATCAGCAAGAAGATCCTAAAACAAAAGCTCATCCATTTGCGTTC
CATGATGCTGGGATTTACACTTGAGGCTTAGCTTTGCTCTGCCAACTTCTTCAGAGCTGACACAGGATGAAGGCAATGCCATCCTCAAAC
ACTGCAGGCATCACAGCTAACAATTGTGAAGTCGTCTTAACTCACCATAAAAAGGAATCCACTCCCAGGCAGCCCTACTTCTTTGCTTTG
CCCAGCATTTTACTGATTCATACATTATCTCACTTGTGCCAACACTCAAGAAGCAGGCTACACTGACACTGGTATTCCTGCCTCCATATT
TTCTTTAAAAGACAAATCAAAGCAGATATATTAAGTGACTGTTCAAGAGCACACTTGGCCCAAGTGGCAGAGCTTGGACTGGATGCATGT
TTTCCAGCTCCTCATCCAGGGCTCTGACCAGTTTAACCTGATGCAGTCACGTGGAGGAGCAGTGCAGGCACAGTATGTCCCATAGGCCCA
GTGAGATGCATTCTTGGTTGGCTGGCCTTCCACTTGGCTACACAGGGATGTACAAGGCGATCCCATCTTGATAAGACCACCACCTCAGAG
TATGGAGCTCAGAGAGGGCAGGCATGAAGTTTCCTTGGCTGGTGCACCTAGAATTGGCTGAACTCATGAGAAGTTGATATAGAACAGTGC
TTGCCACAGAGCGGGGACTCGGTAAGCACTTAATGAATGAATGAATTCTAAGTCAATCCAAGAGTCTGATGATTTCTTGAAAAGGGTGTT
AGCTAAAGGATCTTAGGCATGACTGTAGAATTTGTAGTTGCAATAGAACAGAGAAAGAGGAAGCTTTCTGTCTCCTTAACACTGAGCTGT
CATGTTTTAAAGCTTGCTCACATCTTGGCACATTTAAGAGACAGTCACCCCAGGACTCAAAAATAGGGAAGTAACAGTAACGCAGGGGAA
ACGTTTTCTGTTTGGAGGAGCAAAGGCTGAGAACACTGTGAAAACATTTTGCGCGCACAATAGTAACCTGGGTAAATGCAGCGTGAAGGG
ATTTTAGTCACACGTGGTCTTTCTTACAAGGAAGGTGGTGGGGGTGCAGATGAGGTTGCTAGAGAATGTTAGAGGATCCCTCTCTGGATT
GGAGATAGGGAAAGAAAGTTGCACGGCTGCTGAGGCCCCTTCTAGGTGGCAAGGCTGTGCTCCCTGGTTCTGATGATGTGCCTGGGTGGA
CATGGCCCCTGTGAGTTTGTACAGTCTTGCAGCAGGATCTAGAGGGGGGATTTCCAGCCAGGGCTGCTAGACGGAGGCCTACTCTTCCAT
CTTTCCTGATGGCAGGATGGCCTGGCCAGGGCCTGGAAGACAGAGACCTCCTGCCTCCGCCTCAGTAAGACGACAAGGAAAGGCAAATGC
CCAAGGGAAAGAAAAGGAAGGCTCTTCTCCCCAGAGTTCCCCATGCAGACATGAGTGCGTGCTCAGTTCAGAATCACTTCTGAGAACTCA
TCCCTAATGCTGCAGATTTGGGCTGGAACAGATTCACACTGTCTGGTTTCACCGAGGACATGAAACTCCACCTTGCGGGGATAAAGAGAG
AAAAACAAATTCATCAAATGGAAGACACATTGAAAGTGTTTTTCCTTAATGCTTATCCTGTTTTTAAACCATTATTTCCAAGTTGACACC

>In-frame_ENST00000446868_ENST00000394660_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=197AA_start in transcript=942_stop in transcript=1535
MDLLEFHMTFMPGFAKCFKYCNCVMIHPQTVTFIFLMNLQCGQRLEWAAHLCPTWHQLASCKVMQRLGPREIIHSYIWPLMLAGNSPGAA
GLNAYRWPLLVAWASSQHGVWIPRMSIPGSQEPCRSCILFIPLPWKLHGITSTILHQLELTQTCLGLRGEEILLGSFMKNTVCHMKHLQN

--------------------------------------------------------------
>In-frame_ENST00000446868_ENST00000302987_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=672nt_BP=93nt
GCGAGCGGGGGCGCGGGTGGCGCGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACAGCT
ACGGTTCACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAGTCT
CTCAAGGGGACCACGCACCATGATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACT
CCAGAGGCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGCAGAG
GCCACAGTCTGCACGGTGACACTGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAG
CCTCTCACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGTGGC
ACTGCCATGCAGGGCCTCACACGGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAA

>In-frame_ENST00000446868_ENST00000302987_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=184AA_start in transcript=117_stop in transcript=671
MASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLE
KMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTA

--------------------------------------------------------------
>In-frame_ENST00000446868_ENST00000394652_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=957nt_BP=93nt
GCGAGCGGGGGCGCGGGTGGCGCGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACAGCT
ACGGTTCACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAGTCT
CTCAAGGGGACCACGCACCATGATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACT
CCAGAGGCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGCAGAG
GCCACAGTCTGCACGGTGACACTGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAG
CCTCTCACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGTGGC
ACTGCCATGCAGGGCCTCACACGGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAA
AGCCTCCAGTCCAAGGAAACCACAGCTGCTGGAGACTCCTAGGCAGGACATGCTGAAGCCAAAGCCAATAACACACAGCTAACACACAGC
TCCCATAACCGCTGATTCTCAGGGTCTCTGCTGCCGCCCCACCCAGATGGGGGAAAGCACAGGTGGGCTTCCCAGTGGCTGCTGCCCAGG
CCCAGACCTTCTAGGACGCCACCCAGCAAAAGGTTGTTCCTAAAATAAGGGCAGAGTCACACGGGGGCAGCTGATACAAATTGCAGACTG

>In-frame_ENST00000446868_ENST00000394652_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=184AA_start in transcript=117_stop in transcript=671
MASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLE
KMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTA

--------------------------------------------------------------
>In-frame_ENST00000361101_ENST00000394660_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=4634nt_BP=93nt
GCGAGCGGGGGCGCGGGTGGCGCGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACAGCT
ACGGTTCACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAGTCT
CTCAAGGGGACCACGCACCATGATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACT
CCAGAGGCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGAGGCC
ACAGTCTGCACGGTGACACTGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAGCCT
CTCACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGTGGCACT
GCCATGCAGGGCCTCACACGGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAAAGC
CTCCAGTCCAAGGAAACCACAGCTGCTGGAGACTCCTAGGCAGGACATGCTGAAGCCAAAGCCAATAACACACAGCTAACACACAGCTCC
CATAACCGCTGATTCTCAGGGTCTCTGCTGCCGCCCCACCCAGATGGGGGAAAGCACAGGTGGGCTTCCCAGTGGCTGCTGCCCAGGCCC
AGACCTTCTAGGACGCCACCCAGCAAAAGGTTGTTCCTAAAATAAGGGCAGAGTCACACGGGGGCAGCTGATACAAATTGCAGACTGTGT
AAAAAGAGAGCTTAATGATAATATTGTGGTGCCACAAATAAAATGGATTTATTAGAATTTCATATGACATTCATGCCTGGCTTCGCAAAA
TGTTTCAAGTACTGTAACTGTGTCATGATTCACCCCCAAACAGTGACATTTATTTTTCTCATGAATCTGCAATGTGGGCAGAGATTGGAA
TGGGCAGCTCATCTCTGTCCCACTTGGCATCAGCTGGCGTCATGCAAAGTCATGCAAAGGCTGGGACCACGTGAGATCATTCACTCATAC
ATCTGGCCGTTGATGTTGGCTGGGAACTCACCTGGGGCTGCTGGCCTGAATGCTTATAGGTGGCCTCTCCTTGTGGCCTGGGCCTCCTCA
CAACATGGTGTCTGGATTCCCAGGATGAGCATCCCAGGATCGCAAGAGCCATGTAGAAGCTGCATCTTGTTTATACCTTTGCCTTGGAAG
TTGCATGGCATCACCTCCACCATACTCCATCAGTTAGAGCTGACACAAACCTGCCTGGGTTTAAGGGGAGAGGAAATATTGCTGGGGTCA
TTTATGAAAAATACAGTTTGTCACATGAAACATTTGCAAAATTGTTTTTGGTTGGATTGGAGAAGTAATCCTAGGGAAGGGTGGTGGAGC
CAGTAAACAGAGGAGTACAGGTGAAGCACCAAGCTCAAAGCGTGGACAGGTGTGCCGACAGAAGGAACCAGCGTGTATATGAGGGTATCA
AATAAAATTGCTACTACTTACCTACCACATGCCAAGCACTGTGCTCAGGGCTAAACGGGCATTGCCTTTAGTGATCACAGCAGCTTCTAC
GGTGTATGGTTCTGTGCCAATGTATTGATAAGAGGGCACACACTGTGTACAGTAAATGGCTTATCCAGCTGGTGAGTGATGCGGCAGATT
GAGTTTTCTTCTGTGATTCGGTGGAGACTATCAGCCCAAGATGCTTTAAGTGCACAACATTACAGGGAATGCCTGAGTGCCTGGCCAAAG
GGATATTTGGTTTGGCCATCTCTGGATGCCTGATTGCCAAGCTCAGGACCAGGCAATGTGACTTTGCATCAGCAACAACCAGCATCCCTT
GACCAGGCCTGGGCCAGAGTATTGGTCTCCTCTCAGCCCCTGATCCTGTGAAGTAAGGATGTGGGGGAAGACCTGGCAAGGACACAGATG
AAACACAAACAATAGTAATTCTCAGGCCATCATCAGTGGAGCCATGTTAATGTAATCTGATGGCTTCTCCAGGGTCCACAGGAAGTGAAG
AATCTGTTTCCCAGCAGTGGACTCAAAACCCATCTGGGCTCCTAACCTTCCTGTAAACCCCTTTAGTGGCTTCATTAGAGCAGGCGTTCA
GCTCACTGTTCTATTCATCTCAAGGAATAATGGGCTTAGAGCAGTTTCTGTCCTGCTGGTTAACTTGTTTGGCCTATTCCATTCTGGATT
TTGTCAAGCAGTAGACAAGCAATTAGACAAGAACTTGGAGGCACCATTTGTATCCACTTTTTAGACTTAATAGAAACATTGAAGATGAAC
ATAATCTACCAACGAAAGACGTGATTCAATTCAACACTCCCTTCCCATGACCCAGGCTGGGCAAGGAGGCCACGTGATGTGGAGGGCACA
TTCCTTGCCTGCACAAACTCACCATCTGTGCACGCAGTGGCCTTCCCTAAAATCAGGGAATTGTTTTAAGTCTTATCAAGCAGCCAAGGG
ATGAAAGAGAAGGTGGGTTTTCATCAAGACTGGAAGGTGGGGACAGGGATGAGCATGGAGCTGGCCGTGGGCCTGGGGTACCAAGAGACT
CCTTGAGAGACCAGGCAAAGCAAGTGATTGGGACAGAGGTTATCTGTCCCAGGTTATCTGGGCATAGATGCAGGTGAGCCCATGGCCCTC
CCAGTACCTCCTGTCTCTGGCCTGTTTTAGAAGGTTCTCTCCTCCCCAAGGAGACACAACAACTCCTAGGGCCACTGAAGATATAACTAT
TGCCCAGGTTTCTGGTCTCTAGGCTGGGGAAGTCCTCTGGGTAGGAATCAGCAAGAAGATCCTAAAACAAAAGCTCATCCATTTGCGTTC
CATGATGCTGGGATTTACACTTGAGGCTTAGCTTTGCTCTGCCAACTTCTTCAGAGCTGACACAGGATGAAGGCAATGCCATCCTCAAAC
ACTGCAGGCATCACAGCTAACAATTGTGAAGTCGTCTTAACTCACCATAAAAAGGAATCCACTCCCAGGCAGCCCTACTTCTTTGCTTTG
CCCAGCATTTTACTGATTCATACATTATCTCACTTGTGCCAACACTCAAGAAGCAGGCTACACTGACACTGGTATTCCTGCCTCCATATT
TTCTTTAAAAGACAAATCAAAGCAGATATATTAAGTGACTGTTCAAGAGCACACTTGGCCCAAGTGGCAGAGCTTGGACTGGATGCATGT
TTTCCAGCTCCTCATCCAGGGCTCTGACCAGTTTAACCTGATGCAGTCACGTGGAGGAGCAGTGCAGGCACAGTATGTCCCATAGGCCCA
GTGAGATGCATTCTTGGTTGGCTGGCCTTCCACTTGGCTACACAGGGATGTACAAGGCGATCCCATCTTGATAAGACCACCACCTCAGAG
TATGGAGCTCAGAGAGGGCAGGCATGAAGTTTCCTTGGCTGGTGCACCTAGAATTGGCTGAACTCATGAGAAGTTGATATAGAACAGTGC
TTGCCACAGAGCGGGGACTCGGTAAGCACTTAATGAATGAATGAATTCTAAGTCAATCCAAGAGTCTGATGATTTCTTGAAAAGGGTGTT
AGCTAAAGGATCTTAGGCATGACTGTAGAATTTGTAGTTGCAATAGAACAGAGAAAGAGGAAGCTTTCTGTCTCCTTAACACTGAGCTGT
CATGTTTTAAAGCTTGCTCACATCTTGGCACATTTAAGAGACAGTCACCCCAGGACTCAAAAATAGGGAAGTAACAGTAACGCAGGGGAA
ACGTTTTCTGTTTGGAGGAGCAAAGGCTGAGAACACTGTGAAAACATTTTGCGCGCACAATAGTAACCTGGGTAAATGCAGCGTGAAGGG
ATTTTAGTCACACGTGGTCTTTCTTACAAGGAAGGTGGTGGGGGTGCAGATGAGGTTGCTAGAGAATGTTAGAGGATCCCTCTCTGGATT
GGAGATAGGGAAAGAAAGTTGCACGGCTGCTGAGGCCCCTTCTAGGTGGCAAGGCTGTGCTCCCTGGTTCTGATGATGTGCCTGGGTGGA
CATGGCCCCTGTGAGTTTGTACAGTCTTGCAGCAGGATCTAGAGGGGGGATTTCCAGCCAGGGCTGCTAGACGGAGGCCTACTCTTCCAT
CTTTCCTGATGGCAGGATGGCCTGGCCAGGGCCTGGAAGACAGAGACCTCCTGCCTCCGCCTCAGTAAGACGACAAGGAAAGGCAAATGC
CCAAGGGAAAGAAAAGGAAGGCTCTTCTCCCCAGAGTTCCCCATGCAGACATGAGTGCGTGCTCAGTTCAGAATCACTTCTGAGAACTCA
TCCCTAATGCTGCAGATTTGGGCTGGAACAGATTCACACTGTCTGGTTTCACCGAGGACATGAAACTCCACCTTGCGGGGATAAAGAGAG
AAAAACAAATTCATCAAATGGAAGACACATTGAAAGTGTTTTTCCTTAATGCTTATCCTGTTTTTAAACCATTATTTCCAAGTTGACACC

>In-frame_ENST00000361101_ENST00000394660_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=197AA_start in transcript=942_stop in transcript=1535
MDLLEFHMTFMPGFAKCFKYCNCVMIHPQTVTFIFLMNLQCGQRLEWAAHLCPTWHQLASCKVMQRLGPREIIHSYIWPLMLAGNSPGAA
GLNAYRWPLLVAWASSQHGVWIPRMSIPGSQEPCRSCILFIPLPWKLHGITSTILHQLELTQTCLGLRGEEILLGSFMKNTVCHMKHLQN

--------------------------------------------------------------
>In-frame_ENST00000361101_ENST00000302987_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=672nt_BP=93nt
GCGAGCGGGGGCGCGGGTGGCGCGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACAGCT
ACGGTTCACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAGTCT
CTCAAGGGGACCACGCACCATGATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACT
CCAGAGGCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGCAGAG
GCCACAGTCTGCACGGTGACACTGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAG
CCTCTCACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGTGGC
ACTGCCATGCAGGGCCTCACACGGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAA

>In-frame_ENST00000361101_ENST00000302987_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=184AA_start in transcript=117_stop in transcript=671
MASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLE
KMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTA

--------------------------------------------------------------
>In-frame_ENST00000361101_ENST00000394652_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=957nt_BP=93nt
GCGAGCGGGGGCGCGGGTGGCGCGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACAGCT
ACGGTTCACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAGTCT
CTCAAGGGGACCACGCACCATGATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACT
CCAGAGGCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGCAGAG
GCCACAGTCTGCACGGTGACACTGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAG
CCTCTCACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGTGGC
ACTGCCATGCAGGGCCTCACACGGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAA
AGCCTCCAGTCCAAGGAAACCACAGCTGCTGGAGACTCCTAGGCAGGACATGCTGAAGCCAAAGCCAATAACACACAGCTAACACACAGC
TCCCATAACCGCTGATTCTCAGGGTCTCTGCTGCCGCCCCACCCAGATGGGGGAAAGCACAGGTGGGCTTCCCAGTGGCTGCTGCCCAGG
CCCAGACCTTCTAGGACGCCACCCAGCAAAAGGTTGTTCCTAAAATAAGGGCAGAGTCACACGGGGGCAGCTGATACAAATTGCAGACTG

>In-frame_ENST00000361101_ENST00000394652_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=184AA_start in transcript=117_stop in transcript=671
MASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLE
KMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTA

--------------------------------------------------------------
>In-frame_ENST00000589296_ENST00000394660_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=4637nt_BP=96nt
GAGGCGAGCGGGGGCGCGGGTGGCGCGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACA
GCTACGGTTCACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAG
TCTCTCAAGGGGACCACGCACCATGATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTG
ACTCCAGAGGCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGAG
GCCACAGTCTGCACGGTGACACTGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAG
CCTCTCACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGTGGC
ACTGCCATGCAGGGCCTCACACGGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAA
AGCCTCCAGTCCAAGGAAACCACAGCTGCTGGAGACTCCTAGGCAGGACATGCTGAAGCCAAAGCCAATAACACACAGCTAACACACAGC
TCCCATAACCGCTGATTCTCAGGGTCTCTGCTGCCGCCCCACCCAGATGGGGGAAAGCACAGGTGGGCTTCCCAGTGGCTGCTGCCCAGG
CCCAGACCTTCTAGGACGCCACCCAGCAAAAGGTTGTTCCTAAAATAAGGGCAGAGTCACACGGGGGCAGCTGATACAAATTGCAGACTG
TGTAAAAAGAGAGCTTAATGATAATATTGTGGTGCCACAAATAAAATGGATTTATTAGAATTTCATATGACATTCATGCCTGGCTTCGCA
AAATGTTTCAAGTACTGTAACTGTGTCATGATTCACCCCCAAACAGTGACATTTATTTTTCTCATGAATCTGCAATGTGGGCAGAGATTG
GAATGGGCAGCTCATCTCTGTCCCACTTGGCATCAGCTGGCGTCATGCAAAGTCATGCAAAGGCTGGGACCACGTGAGATCATTCACTCA
TACATCTGGCCGTTGATGTTGGCTGGGAACTCACCTGGGGCTGCTGGCCTGAATGCTTATAGGTGGCCTCTCCTTGTGGCCTGGGCCTCC
TCACAACATGGTGTCTGGATTCCCAGGATGAGCATCCCAGGATCGCAAGAGCCATGTAGAAGCTGCATCTTGTTTATACCTTTGCCTTGG
AAGTTGCATGGCATCACCTCCACCATACTCCATCAGTTAGAGCTGACACAAACCTGCCTGGGTTTAAGGGGAGAGGAAATATTGCTGGGG
TCATTTATGAAAAATACAGTTTGTCACATGAAACATTTGCAAAATTGTTTTTGGTTGGATTGGAGAAGTAATCCTAGGGAAGGGTGGTGG
AGCCAGTAAACAGAGGAGTACAGGTGAAGCACCAAGCTCAAAGCGTGGACAGGTGTGCCGACAGAAGGAACCAGCGTGTATATGAGGGTA
TCAAATAAAATTGCTACTACTTACCTACCACATGCCAAGCACTGTGCTCAGGGCTAAACGGGCATTGCCTTTAGTGATCACAGCAGCTTC
TACGGTGTATGGTTCTGTGCCAATGTATTGATAAGAGGGCACACACTGTGTACAGTAAATGGCTTATCCAGCTGGTGAGTGATGCGGCAG
ATTGAGTTTTCTTCTGTGATTCGGTGGAGACTATCAGCCCAAGATGCTTTAAGTGCACAACATTACAGGGAATGCCTGAGTGCCTGGCCA
AAGGGATATTTGGTTTGGCCATCTCTGGATGCCTGATTGCCAAGCTCAGGACCAGGCAATGTGACTTTGCATCAGCAACAACCAGCATCC
CTTGACCAGGCCTGGGCCAGAGTATTGGTCTCCTCTCAGCCCCTGATCCTGTGAAGTAAGGATGTGGGGGAAGACCTGGCAAGGACACAG
ATGAAACACAAACAATAGTAATTCTCAGGCCATCATCAGTGGAGCCATGTTAATGTAATCTGATGGCTTCTCCAGGGTCCACAGGAAGTG
AAGAATCTGTTTCCCAGCAGTGGACTCAAAACCCATCTGGGCTCCTAACCTTCCTGTAAACCCCTTTAGTGGCTTCATTAGAGCAGGCGT
TCAGCTCACTGTTCTATTCATCTCAAGGAATAATGGGCTTAGAGCAGTTTCTGTCCTGCTGGTTAACTTGTTTGGCCTATTCCATTCTGG
ATTTTGTCAAGCAGTAGACAAGCAATTAGACAAGAACTTGGAGGCACCATTTGTATCCACTTTTTAGACTTAATAGAAACATTGAAGATG
AACATAATCTACCAACGAAAGACGTGATTCAATTCAACACTCCCTTCCCATGACCCAGGCTGGGCAAGGAGGCCACGTGATGTGGAGGGC
ACATTCCTTGCCTGCACAAACTCACCATCTGTGCACGCAGTGGCCTTCCCTAAAATCAGGGAATTGTTTTAAGTCTTATCAAGCAGCCAA
GGGATGAAAGAGAAGGTGGGTTTTCATCAAGACTGGAAGGTGGGGACAGGGATGAGCATGGAGCTGGCCGTGGGCCTGGGGTACCAAGAG
ACTCCTTGAGAGACCAGGCAAAGCAAGTGATTGGGACAGAGGTTATCTGTCCCAGGTTATCTGGGCATAGATGCAGGTGAGCCCATGGCC
CTCCCAGTACCTCCTGTCTCTGGCCTGTTTTAGAAGGTTCTCTCCTCCCCAAGGAGACACAACAACTCCTAGGGCCACTGAAGATATAAC
TATTGCCCAGGTTTCTGGTCTCTAGGCTGGGGAAGTCCTCTGGGTAGGAATCAGCAAGAAGATCCTAAAACAAAAGCTCATCCATTTGCG
TTCCATGATGCTGGGATTTACACTTGAGGCTTAGCTTTGCTCTGCCAACTTCTTCAGAGCTGACACAGGATGAAGGCAATGCCATCCTCA
AACACTGCAGGCATCACAGCTAACAATTGTGAAGTCGTCTTAACTCACCATAAAAAGGAATCCACTCCCAGGCAGCCCTACTTCTTTGCT
TTGCCCAGCATTTTACTGATTCATACATTATCTCACTTGTGCCAACACTCAAGAAGCAGGCTACACTGACACTGGTATTCCTGCCTCCAT
ATTTTCTTTAAAAGACAAATCAAAGCAGATATATTAAGTGACTGTTCAAGAGCACACTTGGCCCAAGTGGCAGAGCTTGGACTGGATGCA
TGTTTTCCAGCTCCTCATCCAGGGCTCTGACCAGTTTAACCTGATGCAGTCACGTGGAGGAGCAGTGCAGGCACAGTATGTCCCATAGGC
CCAGTGAGATGCATTCTTGGTTGGCTGGCCTTCCACTTGGCTACACAGGGATGTACAAGGCGATCCCATCTTGATAAGACCACCACCTCA
GAGTATGGAGCTCAGAGAGGGCAGGCATGAAGTTTCCTTGGCTGGTGCACCTAGAATTGGCTGAACTCATGAGAAGTTGATATAGAACAG
TGCTTGCCACAGAGCGGGGACTCGGTAAGCACTTAATGAATGAATGAATTCTAAGTCAATCCAAGAGTCTGATGATTTCTTGAAAAGGGT
GTTAGCTAAAGGATCTTAGGCATGACTGTAGAATTTGTAGTTGCAATAGAACAGAGAAAGAGGAAGCTTTCTGTCTCCTTAACACTGAGC
TGTCATGTTTTAAAGCTTGCTCACATCTTGGCACATTTAAGAGACAGTCACCCCAGGACTCAAAAATAGGGAAGTAACAGTAACGCAGGG
GAAACGTTTTCTGTTTGGAGGAGCAAAGGCTGAGAACACTGTGAAAACATTTTGCGCGCACAATAGTAACCTGGGTAAATGCAGCGTGAA
GGGATTTTAGTCACACGTGGTCTTTCTTACAAGGAAGGTGGTGGGGGTGCAGATGAGGTTGCTAGAGAATGTTAGAGGATCCCTCTCTGG
ATTGGAGATAGGGAAAGAAAGTTGCACGGCTGCTGAGGCCCCTTCTAGGTGGCAAGGCTGTGCTCCCTGGTTCTGATGATGTGCCTGGGT
GGACATGGCCCCTGTGAGTTTGTACAGTCTTGCAGCAGGATCTAGAGGGGGGATTTCCAGCCAGGGCTGCTAGACGGAGGCCTACTCTTC
CATCTTTCCTGATGGCAGGATGGCCTGGCCAGGGCCTGGAAGACAGAGACCTCCTGCCTCCGCCTCAGTAAGACGACAAGGAAAGGCAAA
TGCCCAAGGGAAAGAAAAGGAAGGCTCTTCTCCCCAGAGTTCCCCATGCAGACATGAGTGCGTGCTCAGTTCAGAATCACTTCTGAGAAC
TCATCCCTAATGCTGCAGATTTGGGCTGGAACAGATTCACACTGTCTGGTTTCACCGAGGACATGAAACTCCACCTTGCGGGGATAAAGA
GAGAAAAACAAATTCATCAAATGGAAGACACATTGAAAGTGTTTTTCCTTAATGCTTATCCTGTTTTTAAACCATTATTTCCAAGTTGAC

>In-frame_ENST00000589296_ENST00000394660_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=197AA_start in transcript=945_stop in transcript=1538
MDLLEFHMTFMPGFAKCFKYCNCVMIHPQTVTFIFLMNLQCGQRLEWAAHLCPTWHQLASCKVMQRLGPREIIHSYIWPLMLAGNSPGAA
GLNAYRWPLLVAWASSQHGVWIPRMSIPGSQEPCRSCILFIPLPWKLHGITSTILHQLELTQTCLGLRGEEILLGSFMKNTVCHMKHLQN

--------------------------------------------------------------
>In-frame_ENST00000589296_ENST00000302987_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=675nt_BP=96nt
GAGGCGAGCGGGGGCGCGGGTGGCGCGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACA
GCTACGGTTCACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAG
TCTCTCAAGGGGACCACGCACCATGATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTG
ACTCCAGAGGCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGCA
GAGGCCACAGTCTGCACGGTGACACTGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGAC
AAGCCTCTCACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGT
GGCACTGCCATGCAGGGCCTCACACGGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGA

>In-frame_ENST00000589296_ENST00000302987_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=184AA_start in transcript=120_stop in transcript=674
MASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLE
KMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTA

--------------------------------------------------------------
>In-frame_ENST00000589296_ENST00000394652_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(transcript)=960nt_BP=96nt
GAGGCGAGCGGGGGCGCGGGTGGCGCGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACCATGGAGGAGGACGACA
GCTACGGTTCACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAG
TCTCTCAAGGGGACCACGCACCATGATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTG
ACTCCAGAGGCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGCA
GAGGCCACAGTCTGCACGGTGACACTGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGAC
AAGCCTCTCACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGT
GGCACTGCCATGCAGGGCCTCACACGGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGA
AAAAGCCTCCAGTCCAAGGAAACCACAGCTGCTGGAGACTCCTAGGCAGGACATGCTGAAGCCAAAGCCAATAACACACAGCTAACACAC
AGCTCCCATAACCGCTGATTCTCAGGGTCTCTGCTGCCGCCCCACCCAGATGGGGGAAAGCACAGGTGGGCTTCCCAGTGGCTGCTGCCC
AGGCCCAGACCTTCTAGGACGCCACCCAGCAAAAGGTTGTTCCTAAAATAAGGGCAGAGTCACACGGGGGCAGCTGATACAAATTGCAGA

>In-frame_ENST00000589296_ENST00000394652_TCGA-HU-8243_CYTH1_chr17_76778283_-_IL16_chr15_81598248_length(amino acids)=184AA_start in transcript=120_stop in transcript=674
MASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLE
KMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CYTH1-IL16


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneIL16chr17:76778283chr15:81598248ENST00000394652371034_1118439.0632.0HTLV-1 tax
TgeneIL16chr17:76778283chr15:81598248ENST00000394652371106_1202439.0632.0PPP1R12A%2C PPP1R12B and PPP1R12C


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneIL16chr17:76778283chr15:81598248ENST000003029871418183_4521140.01333.0GRIN2A
TgeneIL16chr17:76778283chr15:81598248ENST0000039465237183_452439.0632.0GRIN2A
TgeneIL16chr17:76778283chr15:81598248ENST000003946601519183_4521140.01332.0GRIN2A
TgeneIL16chr17:76778283chr15:81598248ENST0000030298714181034_11181140.01333.0HTLV-1 tax
TgeneIL16chr17:76778283chr15:81598248ENST0000039466015191034_11181140.01332.0HTLV-1 tax
TgeneIL16chr17:76778283chr15:81598248ENST0000030298714181106_12021140.01333.0PPP1R12A%2C PPP1R12B and PPP1R12C
TgeneIL16chr17:76778283chr15:81598248ENST0000039466015191106_12021140.01332.0PPP1R12A%2C PPP1R12B and PPP1R12C


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CYTH1-IL16


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CYTH1-IL16


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCYTH1C0004238Atrial Fibrillation1CTD_human
HgeneCYTH1C0235480Paroxysmal atrial fibrillation1CTD_human
HgeneCYTH1C2585653Persistent atrial fibrillation1CTD_human
HgeneCYTH1C3468561familial atrial fibrillation1CTD_human
TgeneIL16C0000786Spontaneous abortion1CTD_human
TgeneIL16C0000822Abortion, Tubal1CTD_human
TgeneIL16C0020517Hypersensitivity1CTD_human
TgeneIL16C0033578Prostatic Neoplasms1CTD_human
TgeneIL16C0376358Malignant neoplasm of prostate1CTD_human
TgeneIL16C1527304Allergic Reaction1CTD_human
TgeneIL16C3830362Early Pregnancy Loss1CTD_human
TgeneIL16C4552766Miscarriage1CTD_human