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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DDX60-SPOCK3 (FusionGDB2 ID:22105)

Fusion Gene Summary for DDX60-SPOCK3

check button Fusion gene summary
Fusion gene informationFusion gene name: DDX60-SPOCK3
Fusion gene ID: 22105
HgeneTgene
Gene symbol

DDX60

SPOCK3

Gene ID

55601

50859

Gene nameDExD/H-box helicase 60SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
Synonyms-HSAJ1454|TES-3|TICN3
Cytomap

4q32.3

4q32.3

Type of geneprotein-codingprotein-coding
Descriptionprobable ATP-dependent RNA helicase DDX60ATP-dependent RNA helicase DDX60DEAD (Asp-Glu-Ala-Asp) box polypeptide 60DEAD box protein 60DEAD-box helicase 60testican-3SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000393743, ENST00000505393, 
ENST00000357154, ENST00000357545, 
ENST00000504953, ENST00000511531, 
ENST00000506886, ENST00000507137, 
ENST00000510741, ENST00000502330, 
ENST00000541354, ENST00000512681, 
ENST00000511269, ENST00000535728, 
ENST00000421836, ENST00000534949, 
ENST00000541637, ENST00000512648, 
Fusion gene scores* DoF score4 X 6 X 4=965 X 5 X 5=125
# samples 56
** MAII scorelog2(5/96*10)=-0.941106310946431
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/125*10)=-1.05889368905357
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DDX60 [Title/Abstract] AND SPOCK3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDDX60(169157402)-SPOCK3(167983688), # samples:2
Anticipated loss of major functional domain due to fusion event.DDX60-SPOCK3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDDX60

GO:0009615

response to virus

21791617


check buttonFusion gene breakpoints across DDX60 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across SPOCK3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-EJ-5509DDX60chr4

169157402

-SPOCK3chr4

167983688

-
ChimerDB4PRADTCGA-EJ-5509DDX60chr4

169157402

-SPOCK3chr4

167983688

-
ChimerDB4PRADTCGA-EJ-5509DDX60chr4

169157403

-SPOCK3chr4

167983688

-
ChimerDB4STADTCGA-BR-A4IY-01ADDX60chr4

169141806

-SPOCK3chr4

167983688

-


Top

Fusion Gene ORF analysis for DDX60-SPOCK3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000393743ENST00000357154DDX60chr4

169157402

-SPOCK3chr4

167983688

-
Frame-shiftENST00000393743ENST00000357545DDX60chr4

169157402

-SPOCK3chr4

167983688

-
Frame-shiftENST00000393743ENST00000504953DDX60chr4

169157402

-SPOCK3chr4

167983688

-
Frame-shiftENST00000393743ENST00000511531DDX60chr4

169157402

-SPOCK3chr4

167983688

-
Frame-shiftENST00000393743ENST00000506886DDX60chr4

169157402

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000507137DDX60chr4

169157402

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000510741DDX60chr4

169157402

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000502330DDX60chr4

169157402

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000541354DDX60chr4

169157402

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000512681DDX60chr4

169157402

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000511269DDX60chr4

169157402

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000535728DDX60chr4

169157402

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000421836DDX60chr4

169157402

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000534949DDX60chr4

169157402

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000541637DDX60chr4

169157402

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000512648DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000357154DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000357545DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000504953DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000511531DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000506886DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000507137DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000510741DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000502330DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000541354DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000512681DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000511269DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000535728DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000421836DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000534949DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000541637DDX60chr4

169157402

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000512648DDX60chr4

169157402

-SPOCK3chr4

167983688

-
Frame-shiftENST00000393743ENST00000357154DDX60chr4

169157403

-SPOCK3chr4

167983688

-
Frame-shiftENST00000393743ENST00000357545DDX60chr4

169157403

-SPOCK3chr4

167983688

-
Frame-shiftENST00000393743ENST00000504953DDX60chr4

169157403

-SPOCK3chr4

167983688

-
Frame-shiftENST00000393743ENST00000511531DDX60chr4

169157403

-SPOCK3chr4

167983688

-
Frame-shiftENST00000393743ENST00000506886DDX60chr4

169157403

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000507137DDX60chr4

169157403

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000510741DDX60chr4

169157403

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000502330DDX60chr4

169157403

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000541354DDX60chr4

169157403

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000512681DDX60chr4

169157403

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000511269DDX60chr4

169157403

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000535728DDX60chr4

169157403

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000421836DDX60chr4

169157403

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000534949DDX60chr4

169157403

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000541637DDX60chr4

169157403

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000512648DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000357154DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000357545DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000504953DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000511531DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000506886DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000507137DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000510741DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000502330DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000541354DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000512681DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000511269DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000535728DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000421836DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000534949DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000541637DDX60chr4

169157403

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000512648DDX60chr4

169157403

-SPOCK3chr4

167983688

-
In-frameENST00000393743ENST00000357154DDX60chr4

169141806

-SPOCK3chr4

167983688

-
In-frameENST00000393743ENST00000357545DDX60chr4

169141806

-SPOCK3chr4

167983688

-
In-frameENST00000393743ENST00000504953DDX60chr4

169141806

-SPOCK3chr4

167983688

-
In-frameENST00000393743ENST00000511531DDX60chr4

169141806

-SPOCK3chr4

167983688

-
In-frameENST00000393743ENST00000506886DDX60chr4

169141806

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000507137DDX60chr4

169141806

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000510741DDX60chr4

169141806

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000502330DDX60chr4

169141806

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000541354DDX60chr4

169141806

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000512681DDX60chr4

169141806

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000511269DDX60chr4

169141806

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000535728DDX60chr4

169141806

-SPOCK3chr4

167983688

-
5CDS-5UTRENST00000393743ENST00000421836DDX60chr4

169141806

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000534949DDX60chr4

169141806

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000541637DDX60chr4

169141806

-SPOCK3chr4

167983688

-
5CDS-intronENST00000393743ENST00000512648DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000357154DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000357545DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000504953DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000511531DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-3CDSENST00000505393ENST00000506886DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000507137DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000510741DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000502330DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000541354DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000512681DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000511269DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000535728DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-5UTRENST00000505393ENST00000421836DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000534949DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000541637DDX60chr4

169141806

-SPOCK3chr4

167983688

-
intron-intronENST00000505393ENST00000512648DDX60chr4

169141806

-SPOCK3chr4

167983688

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000393743DDX60chr4169141806-ENST00000357154SPOCK3chr4167983688-7981533126853821704
ENST00000393743DDX60chr4169141806-ENST00000357545SPOCK3chr4167983688-7978533126853821704
ENST00000393743DDX60chr4169141806-ENST00000504953SPOCK3chr4167983688-7978533126853821704
ENST00000393743DDX60chr4169141806-ENST00000511531SPOCK3chr4167983688-7977533126853821704
ENST00000393743DDX60chr4169141806-ENST00000506886SPOCK3chr4167983688-7977533126853821704

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000393743ENST00000357154DDX60chr4169141806-SPOCK3chr4167983688-0.0001526980.9998473
ENST00000393743ENST00000357545DDX60chr4169141806-SPOCK3chr4167983688-0.0001524730.99984753
ENST00000393743ENST00000504953DDX60chr4169141806-SPOCK3chr4167983688-0.0001524730.99984753
ENST00000393743ENST00000511531DDX60chr4169141806-SPOCK3chr4167983688-0.0001525320.9998474
ENST00000393743ENST00000506886DDX60chr4169141806-SPOCK3chr4167983688-0.0001525320.9998474

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Fusion Genomic Features for DDX60-SPOCK3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for DDX60-SPOCK3


check button Go to

FGviewer for the breakpoints of chr4:169141806-chr4:167983688

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDDX60chr4:169141806chr4:167983688ENST00000393743-37381226_13701679.66666666666671713.0DomainHelicase C-terminal
HgeneDDX60chr4:169141806chr4:167983688ENST00000393743-3738772_9391679.66666666666671713.0DomainHelicase ATP-binding
HgeneDDX60chr4:169141806chr4:167983688ENST00000393743-3738889_8921679.66666666666671713.0MotifNote=DEVH box
HgeneDDX60chr4:169141806chr4:167983688ENST00000393743-3738785_7921679.66666666666671713.0Nucleotide bindingATP
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000357154212394_43666.0437.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000357545111394_43663.0434.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000421836212394_43615.0386.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000502330212394_43666.0437.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000504953111394_43663.0434.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000506886212394_43666.0437.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000510741110394_43663.0394.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000511269010394_43663.0434.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000511531212394_43666.0437.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000051264818394_43663.0314.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000051268108394_4360339.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000053494908394_4360.0341.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000541354110394_4360317.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000054163707394_4360.0339.0Compositional biasNote=Asp-rich
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000357154212133_18566.0437.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000357154212314_38066.0437.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000357545111133_18563.0434.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000357545111314_38063.0434.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000421836212133_18515.0386.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000421836212314_38015.0386.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000502330212133_18566.0437.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000502330212314_38066.0437.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000504953111133_18563.0434.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000504953111314_38063.0434.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000506886212133_18566.0437.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000506886212314_38066.0437.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000510741110133_18563.0394.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000510741110314_38063.0394.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000511269010133_18563.0434.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000511269010314_38063.0434.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000511531212133_18566.0437.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000511531212314_38066.0437.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000051264818133_18563.0314.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000051264818314_38063.0314.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000051268108133_1850339.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000051268108314_3800339.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000053494908133_1850.0341.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000053494908314_3800.0341.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000541354110133_1850317.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST00000541354110314_3800317.0DomainThyroglobulin type-1
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000054163707133_1850.0339.0DomainKazal-like
TgeneSPOCK3chr4:169141806chr4:167983688ENST0000054163707314_3800.0339.0DomainThyroglobulin type-1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for DDX60-SPOCK3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000393743_ENST00000357154_TCGA-BR-A4IY-01A_DDX60_chr4_169141806_-_SPOCK3_chr4_167983688_length(transcript)=7981nt_BP=5331nt
AGGAAACCGAAACTCCCGCCGGATGCATAAAAGACTGGCTGCGGTGGCTCAGAGCGCCGAGTCCTAGGCCAGGTCTGGGGTAACCTGGAA
CTTCCACCTGGGCTCTGCGCTAGGTCTCTGTTTCACTCCCTCCCCGCGGGGCGCGCAGCTCGCGGGTCTTTGGACACCACCGGTCCTGAG
TCCGCGGACTGCCATTTTCATTAAGAACTGCCACTTAGAGGTACCAAAATAAAGGGTATTTGCTACCTTTAATACTTGCCAGTTCAGGTT
GGAGGCACAGGCAGCAGCAAGAATGGAAAGAAATGTTCTTACAACATTTTCACAGGAAATGTCCCAGTTAATTTTGAATGAAATGCCAAA
AGCTGAATATTCCAGTTTATTCAATGATTTTGTTGAATCTGAATTTTTTTTGATTGATGGGGATTCATTACTTATCACATGTATCTGTGA
GATATCATTTAAGCCTGGGCAGAACCTCCATTTCTTCTATCTGGTTGAACGCTATCTTGTGGATCTTATTAGCAAAGGAGGACAATTCAC
CATAGTTTTCTTCAAGGATGCCGAGTATGCGTATTTCAACTTCCCTGAACTTCTTTCTTTGAGAACTGCTTTAATTCTTCATCTTCAGAA
GAATACCACCATTGATGTTCGAACAACATTTTCGAGATGCTTATCAAAAGAGTGGGGAAGTTTCTTGGAAGAGAGTTACCCATATTTCCT
GATAGTTGCAGACGAAGGCCTGAACGATCTACAAACACAGCTTTTCAACTTTTTAATCATTCATTCTTGGGCAAGGAAGGTCAACGTTGT
ACTTTCCTCAGGGCAAGAATCTGATGTTCTTTGCCTTTATGCATACCTTCTTCCAAGCATGTACAGACACCAGATTTTTTCCTGGAAGAA
TAAGCAGAACATTAAAGATGCTTATACAACCCTGCTTAACCAGTTGGAAAGATTTAAGCTTTCAGCATTAGCACCTCTTTTTGGAAGTTT
AAAATGGAATAATATTACGGAAGAGGCACACAAGACTGTATCTCTGCTTACACAAGTCTGGCCAGAAGGATCTGACATTCGGCGTGTCTT
TTGTGTTACTTCATGCTCATTATCTTTGAGAATGTACCATCGCTTTTTAGGAAACAGAGAGCCCTCCTCTGGTCAGGAAACTGAGATCCA
ACAGGTGAACAGTAATTGCTTAACCCTGCAGGAGATGGAAGATTTGTGTAAACTGCATTGTCTCACTGTGGTTTTTCTACTCCATCTGCC
TCTTTCTCAAAGAGCTTGTGCTAGAGTCATCACTTCCCATTGGGCTGAGGACATGAAGCCTTTATTACAAATGAAAAAGTGGTGTGAATA
TTTCATCTTAAGAAATATACATACTTTTGAATTTTGGAATCTGAATTTAATTCACCTTTCTGACTTAAATGATGAGCTTTTGTTGAAGAA
TATTGCTTTTTACTATGAAAATGAAAATGTAAAAGGCCTACATTTGAATTTGGGAGATACCATTATGAAAGATTATGAATATCTCTGGAA
TACCGTATCAAAGTTGGTCAGAGACTTTGAGGTTGGACAGCCATTTCCTCTGAGAACAACAAAAGTTTGTTTTCTTGAAAAGAAACCATC
ACCAATCAAAGACAGCTCCAATGAAATGGTGCCCAATTTGGGTTTTATTCCAACGTCATCTTTTGTGGTTGATAAATTTGCTGGAGATAT
TTTGAAAGATTTGCCTTTTCTAAAGAGTGATGATCCTATTGTTACTTCACTGGTTAAACAAAAGGAATTTGATGAACTTGTGCACTGGCA
TTCTCATAAACCCCTGAGTGATGATTATGACAGGTCCAGGTGTCAGTTTGATGAAAAATCTAGAGACCCTCGTGTTCTTAGATCTGTGCA
AAAGTATCATGTTTTCCAACGGTTTTATGGGAATTCATTAGAAACAGTCTCTTCGAAAATCATCGTGACTCAAACTATTAAGTCAAAGAA
GGATTTTAGTGGGCCCAAGAGCAAAAAGGCACACGAGACCAAGGCTGAAATAATTGCTAGAGAGAATAAGAAAAGGTTATTTGCCAGGGA
AGAACAAAAGGAAGAGCAAAAGTGGAATGCTTTGTCATTTTCTATTGAAGAGCAATTGAAAGAAAATTTACACTCTGGAATAAAGAGCCT
GGAAGATTTTTTGAAATCCTGTAAAAGTAGCTGTGTGAAACTTCAGGTTGAAATGGTGGGGTTAACTGCTTGCTTGAAAGCCTGGAAAGA
ACATTGCCGAAGTGAAGAAGGTAAAACCACGAAAGATTTAAGTATAGCTGTTCAGGTGATGAAAAGGATCCACTCCTTGATGGAAAAATA
CTCAGAACTTTTACAAGAAGATGATCGGCAACTCATAGCCAGATGCCTTAAGTATTTAGGATTTGATGAGTTGGCAAGTTCTTTACATCC
AGCCCAGGATGCAGAAAATGATGTAAAAGTGAAGAAAAGGAATAAATATTCAGTTGGCATTGGGCCAGCTCGGTTCCAACTGCAATACAT
GGGCCATTATTTGATACGAGATGAGAGAAAAGACCCAGATCCCAGGGTCCAGGATTTTATTCCCGACACATGGCAGCGAGAGCTCCTTGA
TGTTGTGGATAAGAATGAGTCAGCAGTGATTGTTGCCCCAACGTCCTCAGGCAAAACCTATGCCTCCTACTACTGTATGGAGAAAGTGCT
GAAGGAGAGCGACGACGGGGTGGTCGTGTACGTTGCACCCACAAAGGCCCTTGTTAATCAAGTGGCAGCAACTGTTCAGAATCGTTTTAC
GAAAAATCTGCCAAGTGGTGAAGTTCTCTGTGGTGTTTTCACCAGGGAGTATCGTCATGATGCCTTAAACTGTCAGGTACTTATTACAGT
GCCTGCCTGCTTTGAAATTCTGCTGCTTGCTCCTCATCGCCAAAACTGGGTGAAAAAGATCAGATATGTTATATTTGATGAGGTTCATTG
TCTTGGTGGAGAAATTGGAGCAGAAATCTGGGAACATCTCCTTGTCATGATCCGATGTCCCTTTTTGGCTCTTTCAGCTACCATAAGTAA
TCCTGAACATCTCACCGAGTGGCTACAATCGGTAAAATGGTACTGGAAACAAGAAGACAAAATAATTGAAAATAATACCGCTTCTAAAAG
ACATGTGGGTCGTCAGGCCGGCTTTCCCAAAGACTACTTGCAAGTAAAACAATCGTATAAAGTTAGACTTGTGCTCTATGGAGAGAGGTA
TAATGATCTAGAGAAGCATGTATGTTCAATAAAACATGGTGACATTCATTTTGATCATTTTCACCCATGTGCTGCACTAACAACAGATCA
TATTGAAAGGTATGGATTCCCTCCTGATCTTACCCTTTCACCTCGAGAAAGCATCCAGCTGTATGATGCCATGTTTCAAATTTGGAAAAG
TTGGCCTCGGGCCCAGGAACTGTGCCCAGAAAACTTCATTCATTTTAACAATAAATTAGTCATTAAAAAGATGGATGCTAGGAAATATGA
AGAGAGTCTAAAGGCAGAATTAACAAGTTGGATTAAAAATGGCAACGTAGAGCAGGCCAGAATGGTACTTCAGAATCTTAGTCCTGAAGC
AGATTTGAGTCCAGAAAACATGATCACCATGTTTCCACTTCTAGTTGAAAAACTAAGGAAAATGGAGAAGTTACCTGCACTATTTTTTTT
ATTCAAGTTAGGAGCTGTAGAAAACGCAGCTGAAAGTGTGAGCACTTTCCTAAAGAAAAAGCAGGAGACAAAAAGGCCTCCCAAAGCTGA
TAAAGAAGCCCATGTCATGGCTAACAAACTTCGAAAAGTTAAAAAATCCATAGAGAAACAAAAGATCATAGATGAAAAGAGCCAGAAAAA
AACCAGAAATGTGGATCAAAGCCTAATACATGAAGCTGAACATGATAATCTAGTGAAGTGTCTAGAGAAGAACCTGGAAATCCCACAGGA
CTGCACATATGCTGATCAAAAAGCAGTGGACACTGAGACTTTGCAGAAGGTATTTGGTCGAGTAAAATTTGAAAGAAAAGGTGAAGAATT
GAAAGCCTTGGCAGAAAGGGGTATTGGATATCATCACAGTGCTATGAGTTTCAAAGAAAAACAATTAGTTGAAATCCTCTTTAGAAAAGG
ATATCTTAGGGTGGTGACAGCTACTGGAACACTTGCTTTAGGTGTCAACATGCCTTGTAAATCTGTGGTTTTTGCTCAAAACTCAGTCTA
TCTGGATGCGTTGAATTATAGACAGATGTCTGGCCGTGCTGGAAGAAGAGGTCAAGACCTGATGGGAGATGTATATTTCTTTGATATTCC
ATTCCCCAAAATAGGAAAACTCATAAAATCCAATGTTCCTGAGCTGAGAGGACACTTCCCTCTCAGCATAACCCTGGTCCTGCGACTCAT
GCTGCTGGCTTCCAAGGGAGATGACCCAGAGGATGCCAAGGCAAAGGTGCTATCAGTGCTAAAGCATTCATTGCTGTCCTTCAAGCAACC
CAGAGTCATGGACATGTTAAAACTTTACTTCCTGTTTTCTTTGCAGTTCCTGGTGAAAGAGGGCTATTTAGATCAAGAAGGTAATCCTAT
GGGGTTTGCTGGACTTGTATCACATTTGCATTATCATGAACCTTCTAATCTTGTTTTTGTCAGTTTTCTTGTAAATGGACTCTTCCATGA
TCTCTGTCAGCCAACCAGGAAAGGCTCAAAACATTTTTCTCAAGACGTTATGGAAAAGCTAGTATTAGTATTGGCACATCTCTTTGGAAG
AAGATATTTTCCACCAAAGTTCCAAGATGCACACTTCGAGTTTTATCAATCAAAGGTGTTCCTTGATGATCTCCCTGAGGATTTTAGTGA
TGCTTTAGATGAATATAACATGAAAATTATGGAGGACTTTACCACTTTCCTACGAATTGTTTCCAAACTGGCTGATATGAATCAGGAATA
TCAACTCCCATTGTCAAAAATCAAATTCACAGGTAAAGAATGTGAAGACTCTCAACTCGTATCTCATTTGATGAGCTGCAAGGAAGGAAG
AGTAGCAATTTCACCATTTGTTTGTCTGTCTGGGAACTTTGATGATGATTTGCTTCGACTAGAAACTCCAAACCATGTTACTCTAGGCAC
AATCGGTGTCAATCGCTCTCAGGCTCCAGTGCTGTTGTCACAGAAATTTGATAACCGAGGAAGGAAAATGTCGCTTAATGCCTATGCACT
GGATTTCTACAAACATGGTTCCTTGATAGGATTAGTCCAGGATAACAGGATGAATGAAGGAGATGCTTATTATTTGTTGAAGGATTTTGC
ACTCACCATTAAATCTATCAGGATGATTATTTCCGCACTTGGAGTCCAGGAAAACCCTTCGATCAGGCTTTAGATCCAGCTAAGGATCCA
TGCTTAAAGATGAAATGTAGTCGCCATAAAGTATGCATTGCTCAAGATTCTCAGACTGCAGTCTGCATTAGTCACCGGAGGCTTACACAC
AGGATGAAAGAAGCAGGAGTAGACCATAGGCAGTGGAGGGGTCCCATATTATCCACCTGCAAGCAGTGCCCAGTGGTCTATCCCAGCCCT
GTTTGTGGTTCAGATGGTCATACCTACTCTTTTCAGTGCAAACTAGAATATCAGGCATGTGTCTTAGGAAAACAGATCTCAGTCAAATGT
GAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGAAATGTTAAGAGAGCATGCAGTGACCTGGAGTTCAGGGAAGTG
GCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGTCAAAACAAGAAGACAAAAACATTGCTGAGGCCTGAGAGAAGC
AGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGGATGTTTAACAGACTTGATACAAACTATGACCTGCTATTGGAC
CAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACCAAGGCATTCTTCAATTCTTGTGACACATACAAGGACAGTTTA
ATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCACCTTGCCAGACTGAGCTCAGCAATATTCAGAAGCGGCAAGGG
GTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGTTACTACAAGCCAACACAATGTCATGGCAGTGTTGGACAGTGC
TGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAATGGTGTTGCAGATTGTGCTATAGATTTTGAGATCTCCGGAGAT
TTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAAGACGATATTATGAATGATGAAGATGAAATTGAAGATGATGAT
GAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATACATTTGATTGATGACAGTTGAAATCAATAAATTCTACATTTCT
AATATTTACAAAAATGATAGCCTATTTAAAATTATCTTCTTCCCCAATAACAAAATGATTCTAAACCTCACATATATTTTGTATAATTAT
TTGAAAAATTGCAGCTAAAGTTATAGAACTTTATGTTTAAATAAGAATCATTTGCTTTGAGTTTTTATATTCCTTACACAAAAAGAAAAT
ACATATGCAGTCTAGTCAGACAAAATAAAGTTTTGAAGTGCTACTATAATAAGTTTTTCACGAGAACAAACTTTGTAAATCTTCCATAAG
CAAAATGACAGCTAGTGCTTGGGATCGTACATGTTAATTTTCTGAAAGATAATTCTAAGTGAAATTTAAAATAAATAAATTTTTAATGAC
CTGGGTCTTAAGGATTTAGGAAAAATATGCATGCTTTAATTGCATTTCCAAAGTAGCATCTTGCTAGACCTAGTTGAGTCAGGATAACAG
AGAGATACCACATGGCAAGAAAAACAAAGTGACAATTGTAGAGTCCTCAATTGTGTTTACATTAATAGTGGTGTTTTTACCTATGAAATT
ATTCTGGATCTAATAGGACATTTTACAAAATGGCAAGTATGGAAAACCATGGATTCTGAAAGTTAAAAATTTAGTTGTTCTCCCCAATGT
GTATTTTAATTTGGATGGCAGTCTCATGCAGATTTTTTAAAAGATTCTTTAATAACATGATTTGTTTGCCTTTCTAGATTTCTTTATCTT
TCTGACCAGCAACTTAGGGAGCAGAATTTAAATTAGGAAGACAAAGGGAAAGATTCATTTAAACCATATTTTTACAAAGTTTGTCATTTG
CCCCAAGGTCAAATTTTAAATTCTTAATTTTCATTTTATTTCCCATTTTAGGTAAAAGTTTGCATTTAATCTTAGAATTATGTTATTTTT
GTTAGTAGTGTGGAAACTTAGAGAACTTATTGTATGGTGCCTTGCAAAAATAGAGATAGAAAGATTTTAGCATGCATACCAATATAGTAT
ATTACGCAATATATAAGCACACCTAATTAACAGATTAATATCAGTAAAGGTATTGCTGCTGGAATGAAGAAAATGGGATACGTTTGTTTC
TTTTTTTCTATTGTTACATAATTGCCATGTGGACTTGTTTATGATTATTGTGTAGAGTAGCATTTAAGATTTAACTGTAGCAAAAATTAC
TTTAACCGCTGTATTTAAGTTAGCATGTTAATTAATTGTGTAGACATTTTGGCACACCATCACTTTTAACTATATCATACCAATGGTTTT
GTGCCCATAATAAAAATGGAAAAACCTGTTGAATGTTACGTATTGGTATCTTTAATTTCAACAGTGGGTAAACTGGTTTCCCAGTATACA
ATTCATTGAAAGCAAAATTGATTAATTATTTCCATTTAATTTATACACACTCAATACAAAATTTAATGTTGACTTTACGTAATAAAGTAT

>In-frame_ENST00000393743_ENST00000357154_TCGA-BR-A4IY-01A_DDX60_chr4_169141806_-_SPOCK3_chr4_167983688_length(amino acids)=1704AA_start in transcript=268_stop in transcript=5382
MEAQAAARMERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQNLHFFYLVERYLVDLISKGGQF
TIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVRTTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNV
VLSSGQESDVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITEEAHKTVSLLTQVWPEGSDIRRV
FCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCLTLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCE
YFILRNIHTFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVRDFEVGQPFPLRTTKVCFLEKKP
SPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSV
QKYHVFQRFYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKENLHSGIKS
LEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLH
PAQDAENDVKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKV
LKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVH
CLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAGFPKDYLQVKQSYKVRLVLYGER
YNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFPPDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKY
EESLKAELTSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQETKRPPKA
DKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEE
LKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFFDI
PFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNP
MGFAGLVSHLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKFQDAHFEFYQSKVFLDDLPEDFS
DALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKIKFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLG

--------------------------------------------------------------
>In-frame_ENST00000393743_ENST00000357545_TCGA-BR-A4IY-01A_DDX60_chr4_169141806_-_SPOCK3_chr4_167983688_length(transcript)=7978nt_BP=5331nt
AGGAAACCGAAACTCCCGCCGGATGCATAAAAGACTGGCTGCGGTGGCTCAGAGCGCCGAGTCCTAGGCCAGGTCTGGGGTAACCTGGAA
CTTCCACCTGGGCTCTGCGCTAGGTCTCTGTTTCACTCCCTCCCCGCGGGGCGCGCAGCTCGCGGGTCTTTGGACACCACCGGTCCTGAG
TCCGCGGACTGCCATTTTCATTAAGAACTGCCACTTAGAGGTACCAAAATAAAGGGTATTTGCTACCTTTAATACTTGCCAGTTCAGGTT
GGAGGCACAGGCAGCAGCAAGAATGGAAAGAAATGTTCTTACAACATTTTCACAGGAAATGTCCCAGTTAATTTTGAATGAAATGCCAAA
AGCTGAATATTCCAGTTTATTCAATGATTTTGTTGAATCTGAATTTTTTTTGATTGATGGGGATTCATTACTTATCACATGTATCTGTGA
GATATCATTTAAGCCTGGGCAGAACCTCCATTTCTTCTATCTGGTTGAACGCTATCTTGTGGATCTTATTAGCAAAGGAGGACAATTCAC
CATAGTTTTCTTCAAGGATGCCGAGTATGCGTATTTCAACTTCCCTGAACTTCTTTCTTTGAGAACTGCTTTAATTCTTCATCTTCAGAA
GAATACCACCATTGATGTTCGAACAACATTTTCGAGATGCTTATCAAAAGAGTGGGGAAGTTTCTTGGAAGAGAGTTACCCATATTTCCT
GATAGTTGCAGACGAAGGCCTGAACGATCTACAAACACAGCTTTTCAACTTTTTAATCATTCATTCTTGGGCAAGGAAGGTCAACGTTGT
ACTTTCCTCAGGGCAAGAATCTGATGTTCTTTGCCTTTATGCATACCTTCTTCCAAGCATGTACAGACACCAGATTTTTTCCTGGAAGAA
TAAGCAGAACATTAAAGATGCTTATACAACCCTGCTTAACCAGTTGGAAAGATTTAAGCTTTCAGCATTAGCACCTCTTTTTGGAAGTTT
AAAATGGAATAATATTACGGAAGAGGCACACAAGACTGTATCTCTGCTTACACAAGTCTGGCCAGAAGGATCTGACATTCGGCGTGTCTT
TTGTGTTACTTCATGCTCATTATCTTTGAGAATGTACCATCGCTTTTTAGGAAACAGAGAGCCCTCCTCTGGTCAGGAAACTGAGATCCA
ACAGGTGAACAGTAATTGCTTAACCCTGCAGGAGATGGAAGATTTGTGTAAACTGCATTGTCTCACTGTGGTTTTTCTACTCCATCTGCC
TCTTTCTCAAAGAGCTTGTGCTAGAGTCATCACTTCCCATTGGGCTGAGGACATGAAGCCTTTATTACAAATGAAAAAGTGGTGTGAATA
TTTCATCTTAAGAAATATACATACTTTTGAATTTTGGAATCTGAATTTAATTCACCTTTCTGACTTAAATGATGAGCTTTTGTTGAAGAA
TATTGCTTTTTACTATGAAAATGAAAATGTAAAAGGCCTACATTTGAATTTGGGAGATACCATTATGAAAGATTATGAATATCTCTGGAA
TACCGTATCAAAGTTGGTCAGAGACTTTGAGGTTGGACAGCCATTTCCTCTGAGAACAACAAAAGTTTGTTTTCTTGAAAAGAAACCATC
ACCAATCAAAGACAGCTCCAATGAAATGGTGCCCAATTTGGGTTTTATTCCAACGTCATCTTTTGTGGTTGATAAATTTGCTGGAGATAT
TTTGAAAGATTTGCCTTTTCTAAAGAGTGATGATCCTATTGTTACTTCACTGGTTAAACAAAAGGAATTTGATGAACTTGTGCACTGGCA
TTCTCATAAACCCCTGAGTGATGATTATGACAGGTCCAGGTGTCAGTTTGATGAAAAATCTAGAGACCCTCGTGTTCTTAGATCTGTGCA
AAAGTATCATGTTTTCCAACGGTTTTATGGGAATTCATTAGAAACAGTCTCTTCGAAAATCATCGTGACTCAAACTATTAAGTCAAAGAA
GGATTTTAGTGGGCCCAAGAGCAAAAAGGCACACGAGACCAAGGCTGAAATAATTGCTAGAGAGAATAAGAAAAGGTTATTTGCCAGGGA
AGAACAAAAGGAAGAGCAAAAGTGGAATGCTTTGTCATTTTCTATTGAAGAGCAATTGAAAGAAAATTTACACTCTGGAATAAAGAGCCT
GGAAGATTTTTTGAAATCCTGTAAAAGTAGCTGTGTGAAACTTCAGGTTGAAATGGTGGGGTTAACTGCTTGCTTGAAAGCCTGGAAAGA
ACATTGCCGAAGTGAAGAAGGTAAAACCACGAAAGATTTAAGTATAGCTGTTCAGGTGATGAAAAGGATCCACTCCTTGATGGAAAAATA
CTCAGAACTTTTACAAGAAGATGATCGGCAACTCATAGCCAGATGCCTTAAGTATTTAGGATTTGATGAGTTGGCAAGTTCTTTACATCC
AGCCCAGGATGCAGAAAATGATGTAAAAGTGAAGAAAAGGAATAAATATTCAGTTGGCATTGGGCCAGCTCGGTTCCAACTGCAATACAT
GGGCCATTATTTGATACGAGATGAGAGAAAAGACCCAGATCCCAGGGTCCAGGATTTTATTCCCGACACATGGCAGCGAGAGCTCCTTGA
TGTTGTGGATAAGAATGAGTCAGCAGTGATTGTTGCCCCAACGTCCTCAGGCAAAACCTATGCCTCCTACTACTGTATGGAGAAAGTGCT
GAAGGAGAGCGACGACGGGGTGGTCGTGTACGTTGCACCCACAAAGGCCCTTGTTAATCAAGTGGCAGCAACTGTTCAGAATCGTTTTAC
GAAAAATCTGCCAAGTGGTGAAGTTCTCTGTGGTGTTTTCACCAGGGAGTATCGTCATGATGCCTTAAACTGTCAGGTACTTATTACAGT
GCCTGCCTGCTTTGAAATTCTGCTGCTTGCTCCTCATCGCCAAAACTGGGTGAAAAAGATCAGATATGTTATATTTGATGAGGTTCATTG
TCTTGGTGGAGAAATTGGAGCAGAAATCTGGGAACATCTCCTTGTCATGATCCGATGTCCCTTTTTGGCTCTTTCAGCTACCATAAGTAA
TCCTGAACATCTCACCGAGTGGCTACAATCGGTAAAATGGTACTGGAAACAAGAAGACAAAATAATTGAAAATAATACCGCTTCTAAAAG
ACATGTGGGTCGTCAGGCCGGCTTTCCCAAAGACTACTTGCAAGTAAAACAATCGTATAAAGTTAGACTTGTGCTCTATGGAGAGAGGTA
TAATGATCTAGAGAAGCATGTATGTTCAATAAAACATGGTGACATTCATTTTGATCATTTTCACCCATGTGCTGCACTAACAACAGATCA
TATTGAAAGGTATGGATTCCCTCCTGATCTTACCCTTTCACCTCGAGAAAGCATCCAGCTGTATGATGCCATGTTTCAAATTTGGAAAAG
TTGGCCTCGGGCCCAGGAACTGTGCCCAGAAAACTTCATTCATTTTAACAATAAATTAGTCATTAAAAAGATGGATGCTAGGAAATATGA
AGAGAGTCTAAAGGCAGAATTAACAAGTTGGATTAAAAATGGCAACGTAGAGCAGGCCAGAATGGTACTTCAGAATCTTAGTCCTGAAGC
AGATTTGAGTCCAGAAAACATGATCACCATGTTTCCACTTCTAGTTGAAAAACTAAGGAAAATGGAGAAGTTACCTGCACTATTTTTTTT
ATTCAAGTTAGGAGCTGTAGAAAACGCAGCTGAAAGTGTGAGCACTTTCCTAAAGAAAAAGCAGGAGACAAAAAGGCCTCCCAAAGCTGA
TAAAGAAGCCCATGTCATGGCTAACAAACTTCGAAAAGTTAAAAAATCCATAGAGAAACAAAAGATCATAGATGAAAAGAGCCAGAAAAA
AACCAGAAATGTGGATCAAAGCCTAATACATGAAGCTGAACATGATAATCTAGTGAAGTGTCTAGAGAAGAACCTGGAAATCCCACAGGA
CTGCACATATGCTGATCAAAAAGCAGTGGACACTGAGACTTTGCAGAAGGTATTTGGTCGAGTAAAATTTGAAAGAAAAGGTGAAGAATT
GAAAGCCTTGGCAGAAAGGGGTATTGGATATCATCACAGTGCTATGAGTTTCAAAGAAAAACAATTAGTTGAAATCCTCTTTAGAAAAGG
ATATCTTAGGGTGGTGACAGCTACTGGAACACTTGCTTTAGGTGTCAACATGCCTTGTAAATCTGTGGTTTTTGCTCAAAACTCAGTCTA
TCTGGATGCGTTGAATTATAGACAGATGTCTGGCCGTGCTGGAAGAAGAGGTCAAGACCTGATGGGAGATGTATATTTCTTTGATATTCC
ATTCCCCAAAATAGGAAAACTCATAAAATCCAATGTTCCTGAGCTGAGAGGACACTTCCCTCTCAGCATAACCCTGGTCCTGCGACTCAT
GCTGCTGGCTTCCAAGGGAGATGACCCAGAGGATGCCAAGGCAAAGGTGCTATCAGTGCTAAAGCATTCATTGCTGTCCTTCAAGCAACC
CAGAGTCATGGACATGTTAAAACTTTACTTCCTGTTTTCTTTGCAGTTCCTGGTGAAAGAGGGCTATTTAGATCAAGAAGGTAATCCTAT
GGGGTTTGCTGGACTTGTATCACATTTGCATTATCATGAACCTTCTAATCTTGTTTTTGTCAGTTTTCTTGTAAATGGACTCTTCCATGA
TCTCTGTCAGCCAACCAGGAAAGGCTCAAAACATTTTTCTCAAGACGTTATGGAAAAGCTAGTATTAGTATTGGCACATCTCTTTGGAAG
AAGATATTTTCCACCAAAGTTCCAAGATGCACACTTCGAGTTTTATCAATCAAAGGTGTTCCTTGATGATCTCCCTGAGGATTTTAGTGA
TGCTTTAGATGAATATAACATGAAAATTATGGAGGACTTTACCACTTTCCTACGAATTGTTTCCAAACTGGCTGATATGAATCAGGAATA
TCAACTCCCATTGTCAAAAATCAAATTCACAGGTAAAGAATGTGAAGACTCTCAACTCGTATCTCATTTGATGAGCTGCAAGGAAGGAAG
AGTAGCAATTTCACCATTTGTTTGTCTGTCTGGGAACTTTGATGATGATTTGCTTCGACTAGAAACTCCAAACCATGTTACTCTAGGCAC
AATCGGTGTCAATCGCTCTCAGGCTCCAGTGCTGTTGTCACAGAAATTTGATAACCGAGGAAGGAAAATGTCGCTTAATGCCTATGCACT
GGATTTCTACAAACATGGTTCCTTGATAGGATTAGTCCAGGATAACAGGATGAATGAAGGAGATGCTTATTATTTGTTGAAGGATTTTGC
ACTCACCATTAAATCTATCAGGATGATTATTTCCGCACTTGGAGTCCAGGAAAACCCTTCGATCAGGCTTTAGATCCAGCTAAGGATCCA
TGCTTAAAGATGAAATGTAGTCGCCATAAAGTATGCATTGCTCAAGATTCTCAGACTGCAGTCTGCATTAGTCACCGGAGGCTTACACAC
AGGATGAAAGAAGCAGGAGTAGACCATAGGCAGTGGAGGGGTCCCATATTATCCACCTGCAAGCAGTGCCCAGTGGTCTATCCCAGCCCT
GTTTGTGGTTCAGATGGTCATACCTACTCTTTTCAGTGCAAACTAGAATATCAGGCATGTGTCTTAGGAAAACAGATCTCAGTCAAATGT
GAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGAAATGTTAAGAGAGCATGCAGTGACCTGGAGTTCAGGGAAGTG
GCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGTCAAAACAAGAAGACAAAAACATTGCTGAGGCCTGAGAGAAGC
AGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGGATGTTTAACAGACTTGATACAAACTATGACCTGCTATTGGAC
CAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACCAAGGCATTCTTCAATTCTTGTGACACATACAAGGACAGTTTA
ATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCACCTTGCCAGACTGAGCTCAGCAATATTCAGAAGCGGCAAGGG
GTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGTTACTACAAGCCAACACAATGTCATGGCAGTGTTGGACAGTGC
TGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAATGGTGTTGCAGATTGTGCTATAGATTTTGAGATCTCCGGAGAT
TTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAAGACGATATTATGAATGATGAAGATGAAATTGAAGATGATGAT
GAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATACATTTGATTGATGACAGTTGAAATCAATAAATTCTACATTTCT
AATATTTACAAAAATGATAGCCTATTTAAAATTATCTTCTTCCCCAATAACAAAATGATTCTAAACCTCACATATATTTTGTATAATTAT
TTGAAAAATTGCAGCTAAAGTTATAGAACTTTATGTTTAAATAAGAATCATTTGCTTTGAGTTTTTATATTCCTTACACAAAAAGAAAAT
ACATATGCAGTCTAGTCAGACAAAATAAAGTTTTGAAGTGCTACTATAATAAGTTTTTCACGAGAACAAACTTTGTAAATCTTCCATAAG
CAAAATGACAGCTAGTGCTTGGGATCGTACATGTTAATTTTCTGAAAGATAATTCTAAGTGAAATTTAAAATAAATAAATTTTTAATGAC
CTGGGTCTTAAGGATTTAGGAAAAATATGCATGCTTTAATTGCATTTCCAAAGTAGCATCTTGCTAGACCTAGTTGAGTCAGGATAACAG
AGAGATACCACATGGCAAGAAAAACAAAGTGACAATTGTAGAGTCCTCAATTGTGTTTACATTAATAGTGGTGTTTTTACCTATGAAATT
ATTCTGGATCTAATAGGACATTTTACAAAATGGCAAGTATGGAAAACCATGGATTCTGAAAGTTAAAAATTTAGTTGTTCTCCCCAATGT
GTATTTTAATTTGGATGGCAGTCTCATGCAGATTTTTTAAAAGATTCTTTAATAACATGATTTGTTTGCCTTTCTAGATTTCTTTATCTT
TCTGACCAGCAACTTAGGGAGCAGAATTTAAATTAGGAAGACAAAGGGAAAGATTCATTTAAACCATATTTTTACAAAGTTTGTCATTTG
CCCCAAGGTCAAATTTTAAATTCTTAATTTTCATTTTATTTCCCATTTTAGGTAAAAGTTTGCATTTAATCTTAGAATTATGTTATTTTT
GTTAGTAGTGTGGAAACTTAGAGAACTTATTGTATGGTGCCTTGCAAAAATAGAGATAGAAAGATTTTAGCATGCATACCAATATAGTAT
ATTACGCAATATATAAGCACACCTAATTAACAGATTAATATCAGTAAAGGTATTGCTGCTGGAATGAAGAAAATGGGATACGTTTGTTTC
TTTTTTTCTATTGTTACATAATTGCCATGTGGACTTGTTTATGATTATTGTGTAGAGTAGCATTTAAGATTTAACTGTAGCAAAAATTAC
TTTAACCGCTGTATTTAAGTTAGCATGTTAATTAATTGTGTAGACATTTTGGCACACCATCACTTTTAACTATATCATACCAATGGTTTT
GTGCCCATAATAAAAATGGAAAAACCTGTTGAATGTTACGTATTGGTATCTTTAATTTCAACAGTGGGTAAACTGGTTTCCCAGTATACA
ATTCATTGAAAGCAAAATTGATTAATTATTTCCATTTAATTTATACACACTCAATACAAAATTTAATGTTGACTTTACGTAATAAAGTAT

>In-frame_ENST00000393743_ENST00000357545_TCGA-BR-A4IY-01A_DDX60_chr4_169141806_-_SPOCK3_chr4_167983688_length(amino acids)=1704AA_start in transcript=268_stop in transcript=5382
MEAQAAARMERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQNLHFFYLVERYLVDLISKGGQF
TIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVRTTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNV
VLSSGQESDVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITEEAHKTVSLLTQVWPEGSDIRRV
FCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCLTLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCE
YFILRNIHTFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVRDFEVGQPFPLRTTKVCFLEKKP
SPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSV
QKYHVFQRFYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKENLHSGIKS
LEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLH
PAQDAENDVKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKV
LKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVH
CLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAGFPKDYLQVKQSYKVRLVLYGER
YNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFPPDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKY
EESLKAELTSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQETKRPPKA
DKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEE
LKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFFDI
PFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNP
MGFAGLVSHLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKFQDAHFEFYQSKVFLDDLPEDFS
DALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKIKFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLG

--------------------------------------------------------------
>In-frame_ENST00000393743_ENST00000504953_TCGA-BR-A4IY-01A_DDX60_chr4_169141806_-_SPOCK3_chr4_167983688_length(transcript)=7978nt_BP=5331nt
AGGAAACCGAAACTCCCGCCGGATGCATAAAAGACTGGCTGCGGTGGCTCAGAGCGCCGAGTCCTAGGCCAGGTCTGGGGTAACCTGGAA
CTTCCACCTGGGCTCTGCGCTAGGTCTCTGTTTCACTCCCTCCCCGCGGGGCGCGCAGCTCGCGGGTCTTTGGACACCACCGGTCCTGAG
TCCGCGGACTGCCATTTTCATTAAGAACTGCCACTTAGAGGTACCAAAATAAAGGGTATTTGCTACCTTTAATACTTGCCAGTTCAGGTT
GGAGGCACAGGCAGCAGCAAGAATGGAAAGAAATGTTCTTACAACATTTTCACAGGAAATGTCCCAGTTAATTTTGAATGAAATGCCAAA
AGCTGAATATTCCAGTTTATTCAATGATTTTGTTGAATCTGAATTTTTTTTGATTGATGGGGATTCATTACTTATCACATGTATCTGTGA
GATATCATTTAAGCCTGGGCAGAACCTCCATTTCTTCTATCTGGTTGAACGCTATCTTGTGGATCTTATTAGCAAAGGAGGACAATTCAC
CATAGTTTTCTTCAAGGATGCCGAGTATGCGTATTTCAACTTCCCTGAACTTCTTTCTTTGAGAACTGCTTTAATTCTTCATCTTCAGAA
GAATACCACCATTGATGTTCGAACAACATTTTCGAGATGCTTATCAAAAGAGTGGGGAAGTTTCTTGGAAGAGAGTTACCCATATTTCCT
GATAGTTGCAGACGAAGGCCTGAACGATCTACAAACACAGCTTTTCAACTTTTTAATCATTCATTCTTGGGCAAGGAAGGTCAACGTTGT
ACTTTCCTCAGGGCAAGAATCTGATGTTCTTTGCCTTTATGCATACCTTCTTCCAAGCATGTACAGACACCAGATTTTTTCCTGGAAGAA
TAAGCAGAACATTAAAGATGCTTATACAACCCTGCTTAACCAGTTGGAAAGATTTAAGCTTTCAGCATTAGCACCTCTTTTTGGAAGTTT
AAAATGGAATAATATTACGGAAGAGGCACACAAGACTGTATCTCTGCTTACACAAGTCTGGCCAGAAGGATCTGACATTCGGCGTGTCTT
TTGTGTTACTTCATGCTCATTATCTTTGAGAATGTACCATCGCTTTTTAGGAAACAGAGAGCCCTCCTCTGGTCAGGAAACTGAGATCCA
ACAGGTGAACAGTAATTGCTTAACCCTGCAGGAGATGGAAGATTTGTGTAAACTGCATTGTCTCACTGTGGTTTTTCTACTCCATCTGCC
TCTTTCTCAAAGAGCTTGTGCTAGAGTCATCACTTCCCATTGGGCTGAGGACATGAAGCCTTTATTACAAATGAAAAAGTGGTGTGAATA
TTTCATCTTAAGAAATATACATACTTTTGAATTTTGGAATCTGAATTTAATTCACCTTTCTGACTTAAATGATGAGCTTTTGTTGAAGAA
TATTGCTTTTTACTATGAAAATGAAAATGTAAAAGGCCTACATTTGAATTTGGGAGATACCATTATGAAAGATTATGAATATCTCTGGAA
TACCGTATCAAAGTTGGTCAGAGACTTTGAGGTTGGACAGCCATTTCCTCTGAGAACAACAAAAGTTTGTTTTCTTGAAAAGAAACCATC
ACCAATCAAAGACAGCTCCAATGAAATGGTGCCCAATTTGGGTTTTATTCCAACGTCATCTTTTGTGGTTGATAAATTTGCTGGAGATAT
TTTGAAAGATTTGCCTTTTCTAAAGAGTGATGATCCTATTGTTACTTCACTGGTTAAACAAAAGGAATTTGATGAACTTGTGCACTGGCA
TTCTCATAAACCCCTGAGTGATGATTATGACAGGTCCAGGTGTCAGTTTGATGAAAAATCTAGAGACCCTCGTGTTCTTAGATCTGTGCA
AAAGTATCATGTTTTCCAACGGTTTTATGGGAATTCATTAGAAACAGTCTCTTCGAAAATCATCGTGACTCAAACTATTAAGTCAAAGAA
GGATTTTAGTGGGCCCAAGAGCAAAAAGGCACACGAGACCAAGGCTGAAATAATTGCTAGAGAGAATAAGAAAAGGTTATTTGCCAGGGA
AGAACAAAAGGAAGAGCAAAAGTGGAATGCTTTGTCATTTTCTATTGAAGAGCAATTGAAAGAAAATTTACACTCTGGAATAAAGAGCCT
GGAAGATTTTTTGAAATCCTGTAAAAGTAGCTGTGTGAAACTTCAGGTTGAAATGGTGGGGTTAACTGCTTGCTTGAAAGCCTGGAAAGA
ACATTGCCGAAGTGAAGAAGGTAAAACCACGAAAGATTTAAGTATAGCTGTTCAGGTGATGAAAAGGATCCACTCCTTGATGGAAAAATA
CTCAGAACTTTTACAAGAAGATGATCGGCAACTCATAGCCAGATGCCTTAAGTATTTAGGATTTGATGAGTTGGCAAGTTCTTTACATCC
AGCCCAGGATGCAGAAAATGATGTAAAAGTGAAGAAAAGGAATAAATATTCAGTTGGCATTGGGCCAGCTCGGTTCCAACTGCAATACAT
GGGCCATTATTTGATACGAGATGAGAGAAAAGACCCAGATCCCAGGGTCCAGGATTTTATTCCCGACACATGGCAGCGAGAGCTCCTTGA
TGTTGTGGATAAGAATGAGTCAGCAGTGATTGTTGCCCCAACGTCCTCAGGCAAAACCTATGCCTCCTACTACTGTATGGAGAAAGTGCT
GAAGGAGAGCGACGACGGGGTGGTCGTGTACGTTGCACCCACAAAGGCCCTTGTTAATCAAGTGGCAGCAACTGTTCAGAATCGTTTTAC
GAAAAATCTGCCAAGTGGTGAAGTTCTCTGTGGTGTTTTCACCAGGGAGTATCGTCATGATGCCTTAAACTGTCAGGTACTTATTACAGT
GCCTGCCTGCTTTGAAATTCTGCTGCTTGCTCCTCATCGCCAAAACTGGGTGAAAAAGATCAGATATGTTATATTTGATGAGGTTCATTG
TCTTGGTGGAGAAATTGGAGCAGAAATCTGGGAACATCTCCTTGTCATGATCCGATGTCCCTTTTTGGCTCTTTCAGCTACCATAAGTAA
TCCTGAACATCTCACCGAGTGGCTACAATCGGTAAAATGGTACTGGAAACAAGAAGACAAAATAATTGAAAATAATACCGCTTCTAAAAG
ACATGTGGGTCGTCAGGCCGGCTTTCCCAAAGACTACTTGCAAGTAAAACAATCGTATAAAGTTAGACTTGTGCTCTATGGAGAGAGGTA
TAATGATCTAGAGAAGCATGTATGTTCAATAAAACATGGTGACATTCATTTTGATCATTTTCACCCATGTGCTGCACTAACAACAGATCA
TATTGAAAGGTATGGATTCCCTCCTGATCTTACCCTTTCACCTCGAGAAAGCATCCAGCTGTATGATGCCATGTTTCAAATTTGGAAAAG
TTGGCCTCGGGCCCAGGAACTGTGCCCAGAAAACTTCATTCATTTTAACAATAAATTAGTCATTAAAAAGATGGATGCTAGGAAATATGA
AGAGAGTCTAAAGGCAGAATTAACAAGTTGGATTAAAAATGGCAACGTAGAGCAGGCCAGAATGGTACTTCAGAATCTTAGTCCTGAAGC
AGATTTGAGTCCAGAAAACATGATCACCATGTTTCCACTTCTAGTTGAAAAACTAAGGAAAATGGAGAAGTTACCTGCACTATTTTTTTT
ATTCAAGTTAGGAGCTGTAGAAAACGCAGCTGAAAGTGTGAGCACTTTCCTAAAGAAAAAGCAGGAGACAAAAAGGCCTCCCAAAGCTGA
TAAAGAAGCCCATGTCATGGCTAACAAACTTCGAAAAGTTAAAAAATCCATAGAGAAACAAAAGATCATAGATGAAAAGAGCCAGAAAAA
AACCAGAAATGTGGATCAAAGCCTAATACATGAAGCTGAACATGATAATCTAGTGAAGTGTCTAGAGAAGAACCTGGAAATCCCACAGGA
CTGCACATATGCTGATCAAAAAGCAGTGGACACTGAGACTTTGCAGAAGGTATTTGGTCGAGTAAAATTTGAAAGAAAAGGTGAAGAATT
GAAAGCCTTGGCAGAAAGGGGTATTGGATATCATCACAGTGCTATGAGTTTCAAAGAAAAACAATTAGTTGAAATCCTCTTTAGAAAAGG
ATATCTTAGGGTGGTGACAGCTACTGGAACACTTGCTTTAGGTGTCAACATGCCTTGTAAATCTGTGGTTTTTGCTCAAAACTCAGTCTA
TCTGGATGCGTTGAATTATAGACAGATGTCTGGCCGTGCTGGAAGAAGAGGTCAAGACCTGATGGGAGATGTATATTTCTTTGATATTCC
ATTCCCCAAAATAGGAAAACTCATAAAATCCAATGTTCCTGAGCTGAGAGGACACTTCCCTCTCAGCATAACCCTGGTCCTGCGACTCAT
GCTGCTGGCTTCCAAGGGAGATGACCCAGAGGATGCCAAGGCAAAGGTGCTATCAGTGCTAAAGCATTCATTGCTGTCCTTCAAGCAACC
CAGAGTCATGGACATGTTAAAACTTTACTTCCTGTTTTCTTTGCAGTTCCTGGTGAAAGAGGGCTATTTAGATCAAGAAGGTAATCCTAT
GGGGTTTGCTGGACTTGTATCACATTTGCATTATCATGAACCTTCTAATCTTGTTTTTGTCAGTTTTCTTGTAAATGGACTCTTCCATGA
TCTCTGTCAGCCAACCAGGAAAGGCTCAAAACATTTTTCTCAAGACGTTATGGAAAAGCTAGTATTAGTATTGGCACATCTCTTTGGAAG
AAGATATTTTCCACCAAAGTTCCAAGATGCACACTTCGAGTTTTATCAATCAAAGGTGTTCCTTGATGATCTCCCTGAGGATTTTAGTGA
TGCTTTAGATGAATATAACATGAAAATTATGGAGGACTTTACCACTTTCCTACGAATTGTTTCCAAACTGGCTGATATGAATCAGGAATA
TCAACTCCCATTGTCAAAAATCAAATTCACAGGTAAAGAATGTGAAGACTCTCAACTCGTATCTCATTTGATGAGCTGCAAGGAAGGAAG
AGTAGCAATTTCACCATTTGTTTGTCTGTCTGGGAACTTTGATGATGATTTGCTTCGACTAGAAACTCCAAACCATGTTACTCTAGGCAC
AATCGGTGTCAATCGCTCTCAGGCTCCAGTGCTGTTGTCACAGAAATTTGATAACCGAGGAAGGAAAATGTCGCTTAATGCCTATGCACT
GGATTTCTACAAACATGGTTCCTTGATAGGATTAGTCCAGGATAACAGGATGAATGAAGGAGATGCTTATTATTTGTTGAAGGATTTTGC
ACTCACCATTAAATCTATCAGGATGATTATTTCCGCACTTGGAGTCCAGGAAAACCCTTCGATCAGGCTTTAGATCCAGCTAAGGATCCA
TGCTTAAAGATGAAATGTAGTCGCCATAAAGTATGCATTGCTCAAGATTCTCAGACTGCAGTCTGCATTAGTCACCGGAGGCTTACACAC
AGGATGAAAGAAGCAGGAGTAGACCATAGGCAGTGGAGGGGTCCCATATTATCCACCTGCAAGCAGTGCCCAGTGGTCTATCCCAGCCCT
GTTTGTGGTTCAGATGGTCATACCTACTCTTTTCAGTGCAAACTAGAATATCAGGCATGTGTCTTAGGAAAACAGATCTCAGTCAAATGT
GAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGAAATGTTAAGAGAGCATGCAGTGACCTGGAGTTCAGGGAAGTG
GCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGTCAAAACAAGAAGACAAAAACATTGCTGAGGCCTGAGAGAAGC
AGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGGATGTTTAACAGACTTGATACAAACTATGACCTGCTATTGGAC
CAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACCAAGGCATTCTTCAATTCTTGTGACACATACAAGGACAGTTTA
ATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCACCTTGCCAGACTGAGCTCAGCAATATTCAGAAGCGGCAAGGG
GTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGTTACTACAAGCCAACACAATGTCATGGCAGTGTTGGACAGTGC
TGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAATGGTGTTGCAGATTGTGCTATAGATTTTGAGATCTCCGGAGAT
TTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAAGACGATATTATGAATGATGAAGATGAAATTGAAGATGATGAT
GAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATACATTTGATTGATGACAGTTGAAATCAATAAATTCTACATTTCT
AATATTTACAAAAATGATAGCCTATTTAAAATTATCTTCTTCCCCAATAACAAAATGATTCTAAACCTCACATATATTTTGTATAATTAT
TTGAAAAATTGCAGCTAAAGTTATAGAACTTTATGTTTAAATAAGAATCATTTGCTTTGAGTTTTTATATTCCTTACACAAAAAGAAAAT
ACATATGCAGTCTAGTCAGACAAAATAAAGTTTTGAAGTGCTACTATAATAAGTTTTTCACGAGAACAAACTTTGTAAATCTTCCATAAG
CAAAATGACAGCTAGTGCTTGGGATCGTACATGTTAATTTTCTGAAAGATAATTCTAAGTGAAATTTAAAATAAATAAATTTTTAATGAC
CTGGGTCTTAAGGATTTAGGAAAAATATGCATGCTTTAATTGCATTTCCAAAGTAGCATCTTGCTAGACCTAGTTGAGTCAGGATAACAG
AGAGATACCACATGGCAAGAAAAACAAAGTGACAATTGTAGAGTCCTCAATTGTGTTTACATTAATAGTGGTGTTTTTACCTATGAAATT
ATTCTGGATCTAATAGGACATTTTACAAAATGGCAAGTATGGAAAACCATGGATTCTGAAAGTTAAAAATTTAGTTGTTCTCCCCAATGT
GTATTTTAATTTGGATGGCAGTCTCATGCAGATTTTTTAAAAGATTCTTTAATAACATGATTTGTTTGCCTTTCTAGATTTCTTTATCTT
TCTGACCAGCAACTTAGGGAGCAGAATTTAAATTAGGAAGACAAAGGGAAAGATTCATTTAAACCATATTTTTACAAAGTTTGTCATTTG
CCCCAAGGTCAAATTTTAAATTCTTAATTTTCATTTTATTTCCCATTTTAGGTAAAAGTTTGCATTTAATCTTAGAATTATGTTATTTTT
GTTAGTAGTGTGGAAACTTAGAGAACTTATTGTATGGTGCCTTGCAAAAATAGAGATAGAAAGATTTTAGCATGCATACCAATATAGTAT
ATTACGCAATATATAAGCACACCTAATTAACAGATTAATATCAGTAAAGGTATTGCTGCTGGAATGAAGAAAATGGGATACGTTTGTTTC
TTTTTTTCTATTGTTACATAATTGCCATGTGGACTTGTTTATGATTATTGTGTAGAGTAGCATTTAAGATTTAACTGTAGCAAAAATTAC
TTTAACCGCTGTATTTAAGTTAGCATGTTAATTAATTGTGTAGACATTTTGGCACACCATCACTTTTAACTATATCATACCAATGGTTTT
GTGCCCATAATAAAAATGGAAAAACCTGTTGAATGTTACGTATTGGTATCTTTAATTTCAACAGTGGGTAAACTGGTTTCCCAGTATACA
ATTCATTGAAAGCAAAATTGATTAATTATTTCCATTTAATTTATACACACTCAATACAAAATTTAATGTTGACTTTACGTAATAAAGTAT

>In-frame_ENST00000393743_ENST00000504953_TCGA-BR-A4IY-01A_DDX60_chr4_169141806_-_SPOCK3_chr4_167983688_length(amino acids)=1704AA_start in transcript=268_stop in transcript=5382
MEAQAAARMERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQNLHFFYLVERYLVDLISKGGQF
TIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVRTTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNV
VLSSGQESDVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITEEAHKTVSLLTQVWPEGSDIRRV
FCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCLTLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCE
YFILRNIHTFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVRDFEVGQPFPLRTTKVCFLEKKP
SPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSV
QKYHVFQRFYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKENLHSGIKS
LEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLH
PAQDAENDVKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKV
LKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVH
CLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAGFPKDYLQVKQSYKVRLVLYGER
YNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFPPDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKY
EESLKAELTSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQETKRPPKA
DKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEE
LKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFFDI
PFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNP
MGFAGLVSHLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKFQDAHFEFYQSKVFLDDLPEDFS
DALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKIKFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLG

--------------------------------------------------------------
>In-frame_ENST00000393743_ENST00000511531_TCGA-BR-A4IY-01A_DDX60_chr4_169141806_-_SPOCK3_chr4_167983688_length(transcript)=7977nt_BP=5331nt
AGGAAACCGAAACTCCCGCCGGATGCATAAAAGACTGGCTGCGGTGGCTCAGAGCGCCGAGTCCTAGGCCAGGTCTGGGGTAACCTGGAA
CTTCCACCTGGGCTCTGCGCTAGGTCTCTGTTTCACTCCCTCCCCGCGGGGCGCGCAGCTCGCGGGTCTTTGGACACCACCGGTCCTGAG
TCCGCGGACTGCCATTTTCATTAAGAACTGCCACTTAGAGGTACCAAAATAAAGGGTATTTGCTACCTTTAATACTTGCCAGTTCAGGTT
GGAGGCACAGGCAGCAGCAAGAATGGAAAGAAATGTTCTTACAACATTTTCACAGGAAATGTCCCAGTTAATTTTGAATGAAATGCCAAA
AGCTGAATATTCCAGTTTATTCAATGATTTTGTTGAATCTGAATTTTTTTTGATTGATGGGGATTCATTACTTATCACATGTATCTGTGA
GATATCATTTAAGCCTGGGCAGAACCTCCATTTCTTCTATCTGGTTGAACGCTATCTTGTGGATCTTATTAGCAAAGGAGGACAATTCAC
CATAGTTTTCTTCAAGGATGCCGAGTATGCGTATTTCAACTTCCCTGAACTTCTTTCTTTGAGAACTGCTTTAATTCTTCATCTTCAGAA
GAATACCACCATTGATGTTCGAACAACATTTTCGAGATGCTTATCAAAAGAGTGGGGAAGTTTCTTGGAAGAGAGTTACCCATATTTCCT
GATAGTTGCAGACGAAGGCCTGAACGATCTACAAACACAGCTTTTCAACTTTTTAATCATTCATTCTTGGGCAAGGAAGGTCAACGTTGT
ACTTTCCTCAGGGCAAGAATCTGATGTTCTTTGCCTTTATGCATACCTTCTTCCAAGCATGTACAGACACCAGATTTTTTCCTGGAAGAA
TAAGCAGAACATTAAAGATGCTTATACAACCCTGCTTAACCAGTTGGAAAGATTTAAGCTTTCAGCATTAGCACCTCTTTTTGGAAGTTT
AAAATGGAATAATATTACGGAAGAGGCACACAAGACTGTATCTCTGCTTACACAAGTCTGGCCAGAAGGATCTGACATTCGGCGTGTCTT
TTGTGTTACTTCATGCTCATTATCTTTGAGAATGTACCATCGCTTTTTAGGAAACAGAGAGCCCTCCTCTGGTCAGGAAACTGAGATCCA
ACAGGTGAACAGTAATTGCTTAACCCTGCAGGAGATGGAAGATTTGTGTAAACTGCATTGTCTCACTGTGGTTTTTCTACTCCATCTGCC
TCTTTCTCAAAGAGCTTGTGCTAGAGTCATCACTTCCCATTGGGCTGAGGACATGAAGCCTTTATTACAAATGAAAAAGTGGTGTGAATA
TTTCATCTTAAGAAATATACATACTTTTGAATTTTGGAATCTGAATTTAATTCACCTTTCTGACTTAAATGATGAGCTTTTGTTGAAGAA
TATTGCTTTTTACTATGAAAATGAAAATGTAAAAGGCCTACATTTGAATTTGGGAGATACCATTATGAAAGATTATGAATATCTCTGGAA
TACCGTATCAAAGTTGGTCAGAGACTTTGAGGTTGGACAGCCATTTCCTCTGAGAACAACAAAAGTTTGTTTTCTTGAAAAGAAACCATC
ACCAATCAAAGACAGCTCCAATGAAATGGTGCCCAATTTGGGTTTTATTCCAACGTCATCTTTTGTGGTTGATAAATTTGCTGGAGATAT
TTTGAAAGATTTGCCTTTTCTAAAGAGTGATGATCCTATTGTTACTTCACTGGTTAAACAAAAGGAATTTGATGAACTTGTGCACTGGCA
TTCTCATAAACCCCTGAGTGATGATTATGACAGGTCCAGGTGTCAGTTTGATGAAAAATCTAGAGACCCTCGTGTTCTTAGATCTGTGCA
AAAGTATCATGTTTTCCAACGGTTTTATGGGAATTCATTAGAAACAGTCTCTTCGAAAATCATCGTGACTCAAACTATTAAGTCAAAGAA
GGATTTTAGTGGGCCCAAGAGCAAAAAGGCACACGAGACCAAGGCTGAAATAATTGCTAGAGAGAATAAGAAAAGGTTATTTGCCAGGGA
AGAACAAAAGGAAGAGCAAAAGTGGAATGCTTTGTCATTTTCTATTGAAGAGCAATTGAAAGAAAATTTACACTCTGGAATAAAGAGCCT
GGAAGATTTTTTGAAATCCTGTAAAAGTAGCTGTGTGAAACTTCAGGTTGAAATGGTGGGGTTAACTGCTTGCTTGAAAGCCTGGAAAGA
ACATTGCCGAAGTGAAGAAGGTAAAACCACGAAAGATTTAAGTATAGCTGTTCAGGTGATGAAAAGGATCCACTCCTTGATGGAAAAATA
CTCAGAACTTTTACAAGAAGATGATCGGCAACTCATAGCCAGATGCCTTAAGTATTTAGGATTTGATGAGTTGGCAAGTTCTTTACATCC
AGCCCAGGATGCAGAAAATGATGTAAAAGTGAAGAAAAGGAATAAATATTCAGTTGGCATTGGGCCAGCTCGGTTCCAACTGCAATACAT
GGGCCATTATTTGATACGAGATGAGAGAAAAGACCCAGATCCCAGGGTCCAGGATTTTATTCCCGACACATGGCAGCGAGAGCTCCTTGA
TGTTGTGGATAAGAATGAGTCAGCAGTGATTGTTGCCCCAACGTCCTCAGGCAAAACCTATGCCTCCTACTACTGTATGGAGAAAGTGCT
GAAGGAGAGCGACGACGGGGTGGTCGTGTACGTTGCACCCACAAAGGCCCTTGTTAATCAAGTGGCAGCAACTGTTCAGAATCGTTTTAC
GAAAAATCTGCCAAGTGGTGAAGTTCTCTGTGGTGTTTTCACCAGGGAGTATCGTCATGATGCCTTAAACTGTCAGGTACTTATTACAGT
GCCTGCCTGCTTTGAAATTCTGCTGCTTGCTCCTCATCGCCAAAACTGGGTGAAAAAGATCAGATATGTTATATTTGATGAGGTTCATTG
TCTTGGTGGAGAAATTGGAGCAGAAATCTGGGAACATCTCCTTGTCATGATCCGATGTCCCTTTTTGGCTCTTTCAGCTACCATAAGTAA
TCCTGAACATCTCACCGAGTGGCTACAATCGGTAAAATGGTACTGGAAACAAGAAGACAAAATAATTGAAAATAATACCGCTTCTAAAAG
ACATGTGGGTCGTCAGGCCGGCTTTCCCAAAGACTACTTGCAAGTAAAACAATCGTATAAAGTTAGACTTGTGCTCTATGGAGAGAGGTA
TAATGATCTAGAGAAGCATGTATGTTCAATAAAACATGGTGACATTCATTTTGATCATTTTCACCCATGTGCTGCACTAACAACAGATCA
TATTGAAAGGTATGGATTCCCTCCTGATCTTACCCTTTCACCTCGAGAAAGCATCCAGCTGTATGATGCCATGTTTCAAATTTGGAAAAG
TTGGCCTCGGGCCCAGGAACTGTGCCCAGAAAACTTCATTCATTTTAACAATAAATTAGTCATTAAAAAGATGGATGCTAGGAAATATGA
AGAGAGTCTAAAGGCAGAATTAACAAGTTGGATTAAAAATGGCAACGTAGAGCAGGCCAGAATGGTACTTCAGAATCTTAGTCCTGAAGC
AGATTTGAGTCCAGAAAACATGATCACCATGTTTCCACTTCTAGTTGAAAAACTAAGGAAAATGGAGAAGTTACCTGCACTATTTTTTTT
ATTCAAGTTAGGAGCTGTAGAAAACGCAGCTGAAAGTGTGAGCACTTTCCTAAAGAAAAAGCAGGAGACAAAAAGGCCTCCCAAAGCTGA
TAAAGAAGCCCATGTCATGGCTAACAAACTTCGAAAAGTTAAAAAATCCATAGAGAAACAAAAGATCATAGATGAAAAGAGCCAGAAAAA
AACCAGAAATGTGGATCAAAGCCTAATACATGAAGCTGAACATGATAATCTAGTGAAGTGTCTAGAGAAGAACCTGGAAATCCCACAGGA
CTGCACATATGCTGATCAAAAAGCAGTGGACACTGAGACTTTGCAGAAGGTATTTGGTCGAGTAAAATTTGAAAGAAAAGGTGAAGAATT
GAAAGCCTTGGCAGAAAGGGGTATTGGATATCATCACAGTGCTATGAGTTTCAAAGAAAAACAATTAGTTGAAATCCTCTTTAGAAAAGG
ATATCTTAGGGTGGTGACAGCTACTGGAACACTTGCTTTAGGTGTCAACATGCCTTGTAAATCTGTGGTTTTTGCTCAAAACTCAGTCTA
TCTGGATGCGTTGAATTATAGACAGATGTCTGGCCGTGCTGGAAGAAGAGGTCAAGACCTGATGGGAGATGTATATTTCTTTGATATTCC
ATTCCCCAAAATAGGAAAACTCATAAAATCCAATGTTCCTGAGCTGAGAGGACACTTCCCTCTCAGCATAACCCTGGTCCTGCGACTCAT
GCTGCTGGCTTCCAAGGGAGATGACCCAGAGGATGCCAAGGCAAAGGTGCTATCAGTGCTAAAGCATTCATTGCTGTCCTTCAAGCAACC
CAGAGTCATGGACATGTTAAAACTTTACTTCCTGTTTTCTTTGCAGTTCCTGGTGAAAGAGGGCTATTTAGATCAAGAAGGTAATCCTAT
GGGGTTTGCTGGACTTGTATCACATTTGCATTATCATGAACCTTCTAATCTTGTTTTTGTCAGTTTTCTTGTAAATGGACTCTTCCATGA
TCTCTGTCAGCCAACCAGGAAAGGCTCAAAACATTTTTCTCAAGACGTTATGGAAAAGCTAGTATTAGTATTGGCACATCTCTTTGGAAG
AAGATATTTTCCACCAAAGTTCCAAGATGCACACTTCGAGTTTTATCAATCAAAGGTGTTCCTTGATGATCTCCCTGAGGATTTTAGTGA
TGCTTTAGATGAATATAACATGAAAATTATGGAGGACTTTACCACTTTCCTACGAATTGTTTCCAAACTGGCTGATATGAATCAGGAATA
TCAACTCCCATTGTCAAAAATCAAATTCACAGGTAAAGAATGTGAAGACTCTCAACTCGTATCTCATTTGATGAGCTGCAAGGAAGGAAG
AGTAGCAATTTCACCATTTGTTTGTCTGTCTGGGAACTTTGATGATGATTTGCTTCGACTAGAAACTCCAAACCATGTTACTCTAGGCAC
AATCGGTGTCAATCGCTCTCAGGCTCCAGTGCTGTTGTCACAGAAATTTGATAACCGAGGAAGGAAAATGTCGCTTAATGCCTATGCACT
GGATTTCTACAAACATGGTTCCTTGATAGGATTAGTCCAGGATAACAGGATGAATGAAGGAGATGCTTATTATTTGTTGAAGGATTTTGC
ACTCACCATTAAATCTATCAGGATGATTATTTCCGCACTTGGAGTCCAGGAAAACCCTTCGATCAGGCTTTAGATCCAGCTAAGGATCCA
TGCTTAAAGATGAAATGTAGTCGCCATAAAGTATGCATTGCTCAAGATTCTCAGACTGCAGTCTGCATTAGTCACCGGAGGCTTACACAC
AGGATGAAAGAAGCAGGAGTAGACCATAGGCAGTGGAGGGGTCCCATATTATCCACCTGCAAGCAGTGCCCAGTGGTCTATCCCAGCCCT
GTTTGTGGTTCAGATGGTCATACCTACTCTTTTCAGTGCAAACTAGAATATCAGGCATGTGTCTTAGGAAAACAGATCTCAGTCAAATGT
GAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGAAATGTTAAGAGAGCATGCAGTGACCTGGAGTTCAGGGAAGTG
GCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGTCAAAACAAGAAGACAAAAACATTGCTGAGGCCTGAGAGAAGC
AGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGGATGTTTAACAGACTTGATACAAACTATGACCTGCTATTGGAC
CAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACCAAGGCATTCTTCAATTCTTGTGACACATACAAGGACAGTTTA
ATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCACCTTGCCAGACTGAGCTCAGCAATATTCAGAAGCGGCAAGGG
GTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGTTACTACAAGCCAACACAATGTCATGGCAGTGTTGGACAGTGC
TGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAATGGTGTTGCAGATTGTGCTATAGATTTTGAGATCTCCGGAGAT
TTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAAGACGATATTATGAATGATGAAGATGAAATTGAAGATGATGAT
GAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATACATTTGATTGATGACAGTTGAAATCAATAAATTCTACATTTCT
AATATTTACAAAAATGATAGCCTATTTAAAATTATCTTCTTCCCCAATAACAAAATGATTCTAAACCTCACATATATTTTGTATAATTAT
TTGAAAAATTGCAGCTAAAGTTATAGAACTTTATGTTTAAATAAGAATCATTTGCTTTGAGTTTTTATATTCCTTACACAAAAAGAAAAT
ACATATGCAGTCTAGTCAGACAAAATAAAGTTTTGAAGTGCTACTATAATAAGTTTTTCACGAGAACAAACTTTGTAAATCTTCCATAAG
CAAAATGACAGCTAGTGCTTGGGATCGTACATGTTAATTTTCTGAAAGATAATTCTAAGTGAAATTTAAAATAAATAAATTTTTAATGAC
CTGGGTCTTAAGGATTTAGGAAAAATATGCATGCTTTAATTGCATTTCCAAAGTAGCATCTTGCTAGACCTAGTTGAGTCAGGATAACAG
AGAGATACCACATGGCAAGAAAAACAAAGTGACAATTGTAGAGTCCTCAATTGTGTTTACATTAATAGTGGTGTTTTTACCTATGAAATT
ATTCTGGATCTAATAGGACATTTTACAAAATGGCAAGTATGGAAAACCATGGATTCTGAAAGTTAAAAATTTAGTTGTTCTCCCCAATGT
GTATTTTAATTTGGATGGCAGTCTCATGCAGATTTTTTAAAAGATTCTTTAATAACATGATTTGTTTGCCTTTCTAGATTTCTTTATCTT
TCTGACCAGCAACTTAGGGAGCAGAATTTAAATTAGGAAGACAAAGGGAAAGATTCATTTAAACCATATTTTTACAAAGTTTGTCATTTG
CCCCAAGGTCAAATTTTAAATTCTTAATTTTCATTTTATTTCCCATTTTAGGTAAAAGTTTGCATTTAATCTTAGAATTATGTTATTTTT
GTTAGTAGTGTGGAAACTTAGAGAACTTATTGTATGGTGCCTTGCAAAAATAGAGATAGAAAGATTTTAGCATGCATACCAATATAGTAT
ATTACGCAATATATAAGCACACCTAATTAACAGATTAATATCAGTAAAGGTATTGCTGCTGGAATGAAGAAAATGGGATACGTTTGTTTC
TTTTTTTCTATTGTTACATAATTGCCATGTGGACTTGTTTATGATTATTGTGTAGAGTAGCATTTAAGATTTAACTGTAGCAAAAATTAC
TTTAACCGCTGTATTTAAGTTAGCATGTTAATTAATTGTGTAGACATTTTGGCACACCATCACTTTTAACTATATCATACCAATGGTTTT
GTGCCCATAATAAAAATGGAAAAACCTGTTGAATGTTACGTATTGGTATCTTTAATTTCAACAGTGGGTAAACTGGTTTCCCAGTATACA
ATTCATTGAAAGCAAAATTGATTAATTATTTCCATTTAATTTATACACACTCAATACAAAATTTAATGTTGACTTTACGTAATAAAGTAT

>In-frame_ENST00000393743_ENST00000511531_TCGA-BR-A4IY-01A_DDX60_chr4_169141806_-_SPOCK3_chr4_167983688_length(amino acids)=1704AA_start in transcript=268_stop in transcript=5382
MEAQAAARMERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQNLHFFYLVERYLVDLISKGGQF
TIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVRTTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNV
VLSSGQESDVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITEEAHKTVSLLTQVWPEGSDIRRV
FCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCLTLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCE
YFILRNIHTFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVRDFEVGQPFPLRTTKVCFLEKKP
SPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSV
QKYHVFQRFYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKENLHSGIKS
LEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLH
PAQDAENDVKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKV
LKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVH
CLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAGFPKDYLQVKQSYKVRLVLYGER
YNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFPPDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKY
EESLKAELTSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQETKRPPKA
DKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEE
LKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFFDI
PFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNP
MGFAGLVSHLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKFQDAHFEFYQSKVFLDDLPEDFS
DALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKIKFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLG

--------------------------------------------------------------
>In-frame_ENST00000393743_ENST00000506886_TCGA-BR-A4IY-01A_DDX60_chr4_169141806_-_SPOCK3_chr4_167983688_length(transcript)=7977nt_BP=5331nt
AGGAAACCGAAACTCCCGCCGGATGCATAAAAGACTGGCTGCGGTGGCTCAGAGCGCCGAGTCCTAGGCCAGGTCTGGGGTAACCTGGAA
CTTCCACCTGGGCTCTGCGCTAGGTCTCTGTTTCACTCCCTCCCCGCGGGGCGCGCAGCTCGCGGGTCTTTGGACACCACCGGTCCTGAG
TCCGCGGACTGCCATTTTCATTAAGAACTGCCACTTAGAGGTACCAAAATAAAGGGTATTTGCTACCTTTAATACTTGCCAGTTCAGGTT
GGAGGCACAGGCAGCAGCAAGAATGGAAAGAAATGTTCTTACAACATTTTCACAGGAAATGTCCCAGTTAATTTTGAATGAAATGCCAAA
AGCTGAATATTCCAGTTTATTCAATGATTTTGTTGAATCTGAATTTTTTTTGATTGATGGGGATTCATTACTTATCACATGTATCTGTGA
GATATCATTTAAGCCTGGGCAGAACCTCCATTTCTTCTATCTGGTTGAACGCTATCTTGTGGATCTTATTAGCAAAGGAGGACAATTCAC
CATAGTTTTCTTCAAGGATGCCGAGTATGCGTATTTCAACTTCCCTGAACTTCTTTCTTTGAGAACTGCTTTAATTCTTCATCTTCAGAA
GAATACCACCATTGATGTTCGAACAACATTTTCGAGATGCTTATCAAAAGAGTGGGGAAGTTTCTTGGAAGAGAGTTACCCATATTTCCT
GATAGTTGCAGACGAAGGCCTGAACGATCTACAAACACAGCTTTTCAACTTTTTAATCATTCATTCTTGGGCAAGGAAGGTCAACGTTGT
ACTTTCCTCAGGGCAAGAATCTGATGTTCTTTGCCTTTATGCATACCTTCTTCCAAGCATGTACAGACACCAGATTTTTTCCTGGAAGAA
TAAGCAGAACATTAAAGATGCTTATACAACCCTGCTTAACCAGTTGGAAAGATTTAAGCTTTCAGCATTAGCACCTCTTTTTGGAAGTTT
AAAATGGAATAATATTACGGAAGAGGCACACAAGACTGTATCTCTGCTTACACAAGTCTGGCCAGAAGGATCTGACATTCGGCGTGTCTT
TTGTGTTACTTCATGCTCATTATCTTTGAGAATGTACCATCGCTTTTTAGGAAACAGAGAGCCCTCCTCTGGTCAGGAAACTGAGATCCA
ACAGGTGAACAGTAATTGCTTAACCCTGCAGGAGATGGAAGATTTGTGTAAACTGCATTGTCTCACTGTGGTTTTTCTACTCCATCTGCC
TCTTTCTCAAAGAGCTTGTGCTAGAGTCATCACTTCCCATTGGGCTGAGGACATGAAGCCTTTATTACAAATGAAAAAGTGGTGTGAATA
TTTCATCTTAAGAAATATACATACTTTTGAATTTTGGAATCTGAATTTAATTCACCTTTCTGACTTAAATGATGAGCTTTTGTTGAAGAA
TATTGCTTTTTACTATGAAAATGAAAATGTAAAAGGCCTACATTTGAATTTGGGAGATACCATTATGAAAGATTATGAATATCTCTGGAA
TACCGTATCAAAGTTGGTCAGAGACTTTGAGGTTGGACAGCCATTTCCTCTGAGAACAACAAAAGTTTGTTTTCTTGAAAAGAAACCATC
ACCAATCAAAGACAGCTCCAATGAAATGGTGCCCAATTTGGGTTTTATTCCAACGTCATCTTTTGTGGTTGATAAATTTGCTGGAGATAT
TTTGAAAGATTTGCCTTTTCTAAAGAGTGATGATCCTATTGTTACTTCACTGGTTAAACAAAAGGAATTTGATGAACTTGTGCACTGGCA
TTCTCATAAACCCCTGAGTGATGATTATGACAGGTCCAGGTGTCAGTTTGATGAAAAATCTAGAGACCCTCGTGTTCTTAGATCTGTGCA
AAAGTATCATGTTTTCCAACGGTTTTATGGGAATTCATTAGAAACAGTCTCTTCGAAAATCATCGTGACTCAAACTATTAAGTCAAAGAA
GGATTTTAGTGGGCCCAAGAGCAAAAAGGCACACGAGACCAAGGCTGAAATAATTGCTAGAGAGAATAAGAAAAGGTTATTTGCCAGGGA
AGAACAAAAGGAAGAGCAAAAGTGGAATGCTTTGTCATTTTCTATTGAAGAGCAATTGAAAGAAAATTTACACTCTGGAATAAAGAGCCT
GGAAGATTTTTTGAAATCCTGTAAAAGTAGCTGTGTGAAACTTCAGGTTGAAATGGTGGGGTTAACTGCTTGCTTGAAAGCCTGGAAAGA
ACATTGCCGAAGTGAAGAAGGTAAAACCACGAAAGATTTAAGTATAGCTGTTCAGGTGATGAAAAGGATCCACTCCTTGATGGAAAAATA
CTCAGAACTTTTACAAGAAGATGATCGGCAACTCATAGCCAGATGCCTTAAGTATTTAGGATTTGATGAGTTGGCAAGTTCTTTACATCC
AGCCCAGGATGCAGAAAATGATGTAAAAGTGAAGAAAAGGAATAAATATTCAGTTGGCATTGGGCCAGCTCGGTTCCAACTGCAATACAT
GGGCCATTATTTGATACGAGATGAGAGAAAAGACCCAGATCCCAGGGTCCAGGATTTTATTCCCGACACATGGCAGCGAGAGCTCCTTGA
TGTTGTGGATAAGAATGAGTCAGCAGTGATTGTTGCCCCAACGTCCTCAGGCAAAACCTATGCCTCCTACTACTGTATGGAGAAAGTGCT
GAAGGAGAGCGACGACGGGGTGGTCGTGTACGTTGCACCCACAAAGGCCCTTGTTAATCAAGTGGCAGCAACTGTTCAGAATCGTTTTAC
GAAAAATCTGCCAAGTGGTGAAGTTCTCTGTGGTGTTTTCACCAGGGAGTATCGTCATGATGCCTTAAACTGTCAGGTACTTATTACAGT
GCCTGCCTGCTTTGAAATTCTGCTGCTTGCTCCTCATCGCCAAAACTGGGTGAAAAAGATCAGATATGTTATATTTGATGAGGTTCATTG
TCTTGGTGGAGAAATTGGAGCAGAAATCTGGGAACATCTCCTTGTCATGATCCGATGTCCCTTTTTGGCTCTTTCAGCTACCATAAGTAA
TCCTGAACATCTCACCGAGTGGCTACAATCGGTAAAATGGTACTGGAAACAAGAAGACAAAATAATTGAAAATAATACCGCTTCTAAAAG
ACATGTGGGTCGTCAGGCCGGCTTTCCCAAAGACTACTTGCAAGTAAAACAATCGTATAAAGTTAGACTTGTGCTCTATGGAGAGAGGTA
TAATGATCTAGAGAAGCATGTATGTTCAATAAAACATGGTGACATTCATTTTGATCATTTTCACCCATGTGCTGCACTAACAACAGATCA
TATTGAAAGGTATGGATTCCCTCCTGATCTTACCCTTTCACCTCGAGAAAGCATCCAGCTGTATGATGCCATGTTTCAAATTTGGAAAAG
TTGGCCTCGGGCCCAGGAACTGTGCCCAGAAAACTTCATTCATTTTAACAATAAATTAGTCATTAAAAAGATGGATGCTAGGAAATATGA
AGAGAGTCTAAAGGCAGAATTAACAAGTTGGATTAAAAATGGCAACGTAGAGCAGGCCAGAATGGTACTTCAGAATCTTAGTCCTGAAGC
AGATTTGAGTCCAGAAAACATGATCACCATGTTTCCACTTCTAGTTGAAAAACTAAGGAAAATGGAGAAGTTACCTGCACTATTTTTTTT
ATTCAAGTTAGGAGCTGTAGAAAACGCAGCTGAAAGTGTGAGCACTTTCCTAAAGAAAAAGCAGGAGACAAAAAGGCCTCCCAAAGCTGA
TAAAGAAGCCCATGTCATGGCTAACAAACTTCGAAAAGTTAAAAAATCCATAGAGAAACAAAAGATCATAGATGAAAAGAGCCAGAAAAA
AACCAGAAATGTGGATCAAAGCCTAATACATGAAGCTGAACATGATAATCTAGTGAAGTGTCTAGAGAAGAACCTGGAAATCCCACAGGA
CTGCACATATGCTGATCAAAAAGCAGTGGACACTGAGACTTTGCAGAAGGTATTTGGTCGAGTAAAATTTGAAAGAAAAGGTGAAGAATT
GAAAGCCTTGGCAGAAAGGGGTATTGGATATCATCACAGTGCTATGAGTTTCAAAGAAAAACAATTAGTTGAAATCCTCTTTAGAAAAGG
ATATCTTAGGGTGGTGACAGCTACTGGAACACTTGCTTTAGGTGTCAACATGCCTTGTAAATCTGTGGTTTTTGCTCAAAACTCAGTCTA
TCTGGATGCGTTGAATTATAGACAGATGTCTGGCCGTGCTGGAAGAAGAGGTCAAGACCTGATGGGAGATGTATATTTCTTTGATATTCC
ATTCCCCAAAATAGGAAAACTCATAAAATCCAATGTTCCTGAGCTGAGAGGACACTTCCCTCTCAGCATAACCCTGGTCCTGCGACTCAT
GCTGCTGGCTTCCAAGGGAGATGACCCAGAGGATGCCAAGGCAAAGGTGCTATCAGTGCTAAAGCATTCATTGCTGTCCTTCAAGCAACC
CAGAGTCATGGACATGTTAAAACTTTACTTCCTGTTTTCTTTGCAGTTCCTGGTGAAAGAGGGCTATTTAGATCAAGAAGGTAATCCTAT
GGGGTTTGCTGGACTTGTATCACATTTGCATTATCATGAACCTTCTAATCTTGTTTTTGTCAGTTTTCTTGTAAATGGACTCTTCCATGA
TCTCTGTCAGCCAACCAGGAAAGGCTCAAAACATTTTTCTCAAGACGTTATGGAAAAGCTAGTATTAGTATTGGCACATCTCTTTGGAAG
AAGATATTTTCCACCAAAGTTCCAAGATGCACACTTCGAGTTTTATCAATCAAAGGTGTTCCTTGATGATCTCCCTGAGGATTTTAGTGA
TGCTTTAGATGAATATAACATGAAAATTATGGAGGACTTTACCACTTTCCTACGAATTGTTTCCAAACTGGCTGATATGAATCAGGAATA
TCAACTCCCATTGTCAAAAATCAAATTCACAGGTAAAGAATGTGAAGACTCTCAACTCGTATCTCATTTGATGAGCTGCAAGGAAGGAAG
AGTAGCAATTTCACCATTTGTTTGTCTGTCTGGGAACTTTGATGATGATTTGCTTCGACTAGAAACTCCAAACCATGTTACTCTAGGCAC
AATCGGTGTCAATCGCTCTCAGGCTCCAGTGCTGTTGTCACAGAAATTTGATAACCGAGGAAGGAAAATGTCGCTTAATGCCTATGCACT
GGATTTCTACAAACATGGTTCCTTGATAGGATTAGTCCAGGATAACAGGATGAATGAAGGAGATGCTTATTATTTGTTGAAGGATTTTGC
ACTCACCATTAAATCTATCAGGATGATTATTTCCGCACTTGGAGTCCAGGAAAACCCTTCGATCAGGCTTTAGATCCAGCTAAGGATCCA
TGCTTAAAGATGAAATGTAGTCGCCATAAAGTATGCATTGCTCAAGATTCTCAGACTGCAGTCTGCATTAGTCACCGGAGGCTTACACAC
AGGATGAAAGAAGCAGGAGTAGACCATAGGCAGTGGAGGGGTCCCATATTATCCACCTGCAAGCAGTGCCCAGTGGTCTATCCCAGCCCT
GTTTGTGGTTCAGATGGTCATACCTACTCTTTTCAGTGCAAACTAGAATATCAGGCATGTGTCTTAGGAAAACAGATCTCAGTCAAATGT
GAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGAAATGTTAAGAGAGCATGCAGTGACCTGGAGTTCAGGGAAGTG
GCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGTCAAAACAAGAAGACAAAAACATTGCTGAGGCCTGAGAGAAGC
AGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGGATGTTTAACAGACTTGATACAAACTATGACCTGCTATTGGAC
CAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACCAAGGCATTCTTCAATTCTTGTGACACATACAAGGACAGTTTA
ATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCACCTTGCCAGACTGAGCTCAGCAATATTCAGAAGCGGCAAGGG
GTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGTTACTACAAGCCAACACAATGTCATGGCAGTGTTGGACAGTGC
TGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAATGGTGTTGCAGATTGTGCTATAGATTTTGAGATCTCCGGAGAT
TTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAAGACGATATTATGAATGATGAAGATGAAATTGAAGATGATGAT
GAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATACATTTGATTGATGACAGTTGAAATCAATAAATTCTACATTTCT
AATATTTACAAAAATGATAGCCTATTTAAAATTATCTTCTTCCCCAATAACAAAATGATTCTAAACCTCACATATATTTTGTATAATTAT
TTGAAAAATTGCAGCTAAAGTTATAGAACTTTATGTTTAAATAAGAATCATTTGCTTTGAGTTTTTATATTCCTTACACAAAAAGAAAAT
ACATATGCAGTCTAGTCAGACAAAATAAAGTTTTGAAGTGCTACTATAATAAGTTTTTCACGAGAACAAACTTTGTAAATCTTCCATAAG
CAAAATGACAGCTAGTGCTTGGGATCGTACATGTTAATTTTCTGAAAGATAATTCTAAGTGAAATTTAAAATAAATAAATTTTTAATGAC
CTGGGTCTTAAGGATTTAGGAAAAATATGCATGCTTTAATTGCATTTCCAAAGTAGCATCTTGCTAGACCTAGTTGAGTCAGGATAACAG
AGAGATACCACATGGCAAGAAAAACAAAGTGACAATTGTAGAGTCCTCAATTGTGTTTACATTAATAGTGGTGTTTTTACCTATGAAATT
ATTCTGGATCTAATAGGACATTTTACAAAATGGCAAGTATGGAAAACCATGGATTCTGAAAGTTAAAAATTTAGTTGTTCTCCCCAATGT
GTATTTTAATTTGGATGGCAGTCTCATGCAGATTTTTTAAAAGATTCTTTAATAACATGATTTGTTTGCCTTTCTAGATTTCTTTATCTT
TCTGACCAGCAACTTAGGGAGCAGAATTTAAATTAGGAAGACAAAGGGAAAGATTCATTTAAACCATATTTTTACAAAGTTTGTCATTTG
CCCCAAGGTCAAATTTTAAATTCTTAATTTTCATTTTATTTCCCATTTTAGGTAAAAGTTTGCATTTAATCTTAGAATTATGTTATTTTT
GTTAGTAGTGTGGAAACTTAGAGAACTTATTGTATGGTGCCTTGCAAAAATAGAGATAGAAAGATTTTAGCATGCATACCAATATAGTAT
ATTACGCAATATATAAGCACACCTAATTAACAGATTAATATCAGTAAAGGTATTGCTGCTGGAATGAAGAAAATGGGATACGTTTGTTTC
TTTTTTTCTATTGTTACATAATTGCCATGTGGACTTGTTTATGATTATTGTGTAGAGTAGCATTTAAGATTTAACTGTAGCAAAAATTAC
TTTAACCGCTGTATTTAAGTTAGCATGTTAATTAATTGTGTAGACATTTTGGCACACCATCACTTTTAACTATATCATACCAATGGTTTT
GTGCCCATAATAAAAATGGAAAAACCTGTTGAATGTTACGTATTGGTATCTTTAATTTCAACAGTGGGTAAACTGGTTTCCCAGTATACA
ATTCATTGAAAGCAAAATTGATTAATTATTTCCATTTAATTTATACACACTCAATACAAAATTTAATGTTGACTTTACGTAATAAAGTAT

>In-frame_ENST00000393743_ENST00000506886_TCGA-BR-A4IY-01A_DDX60_chr4_169141806_-_SPOCK3_chr4_167983688_length(amino acids)=1704AA_start in transcript=268_stop in transcript=5382
MEAQAAARMERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQNLHFFYLVERYLVDLISKGGQF
TIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVRTTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNV
VLSSGQESDVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITEEAHKTVSLLTQVWPEGSDIRRV
FCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCLTLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCE
YFILRNIHTFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVRDFEVGQPFPLRTTKVCFLEKKP
SPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSV
QKYHVFQRFYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKENLHSGIKS
LEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLH
PAQDAENDVKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKV
LKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVH
CLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAGFPKDYLQVKQSYKVRLVLYGER
YNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFPPDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKY
EESLKAELTSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQETKRPPKA
DKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEE
LKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFFDI
PFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNP
MGFAGLVSHLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKFQDAHFEFYQSKVFLDDLPEDFS
DALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKIKFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLG

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Fusion Gene PPI Analysis for DDX60-SPOCK3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DDX60-SPOCK3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DDX60-SPOCK3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneDDX60C0021400Influenza1CTD_human