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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DISC1-LYPLAL1 (FusionGDB2 ID:22916)

Fusion Gene Summary for DISC1-LYPLAL1

check button Fusion gene summary
Fusion gene informationFusion gene name: DISC1-LYPLAL1
Fusion gene ID: 22916
HgeneTgene
Gene symbol

DISC1

LYPLAL1

Gene ID

27185

127018

Gene nameDISC1 scaffold proteinlysophospholipase like 1
SynonymsC1orf136|SCZD9Q96AV0
Cytomap

1q42.2

1q41

Type of geneprotein-codingprotein-coding
Descriptiondisrupted in schizophrenia 1 proteinlysophospholipase-like protein 1
Modification date2020031520200320
UniProtAcc

Q9NRI5

Q5VWZ2

Ensembl transtripts involved in fusion geneENST00000602281, ENST00000539444, 
ENST00000602873, ENST00000366633, 
ENST00000366636, ENST00000535983, 
ENST00000537876, ENST00000366637, 
ENST00000439617, ENST00000427560, 
ENST00000317586, 		ENST00000366928, 
ENST00000366927, ENST00000483635, 
Fusion gene scores* DoF score2 X 2 X 2=85 X 5 X 2=50
# samples 25
** MAII scorelog2(2/8*10)=1.32192809488736log2(5/50*10)=0
Context

PubMed: DISC1 [Title/Abstract] AND LYPLAL1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDISC1(231837770)-LYPLAL1(219352489), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DISC1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across LYPLAL1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4READTCGA-AF-4110-01ADISC1chr1

231837770

-LYPLAL1chr1

219352489

+


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Fusion Gene ORF analysis for DISC1-LYPLAL1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000602281ENST00000366928DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000602281ENST00000366927DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
5CDS-3UTRENST00000602281ENST00000483635DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000539444ENST00000366928DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000539444ENST00000366927DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
5CDS-3UTRENST00000539444ENST00000483635DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
intron-3CDSENST00000602873ENST00000366928DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
intron-3CDSENST00000602873ENST00000366927DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
intron-3UTRENST00000602873ENST00000483635DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000366633ENST00000366928DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000366633ENST00000366927DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
5CDS-3UTRENST00000366633ENST00000483635DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000366636ENST00000366928DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000366636ENST00000366927DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
5CDS-3UTRENST00000366636ENST00000483635DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000535983ENST00000366928DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000535983ENST00000366927DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
5CDS-3UTRENST00000535983ENST00000483635DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000537876ENST00000366928DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000537876ENST00000366927DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
5CDS-3UTRENST00000537876ENST00000483635DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
5UTR-3CDSENST00000366637ENST00000366928DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
5UTR-3CDSENST00000366637ENST00000366927DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
5UTR-3UTRENST00000366637ENST00000483635DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000439617ENST00000366928DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
In-frameENST00000439617ENST00000366927DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
5CDS-3UTRENST00000439617ENST00000483635DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
intron-3CDSENST00000427560ENST00000366928DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
intron-3CDSENST00000427560ENST00000366927DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
intron-3UTRENST00000427560ENST00000483635DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
intron-3CDSENST00000317586ENST00000366928DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
intron-3CDSENST00000317586ENST00000366927DISC1chr1

231837770

-LYPLAL1chr1

219352489

+
intron-3UTRENST00000317586ENST00000483635DISC1chr1

231837770

-LYPLAL1chr1

219352489

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000602281DISC1chr1231837770-ENST00000366928LYPLAL1chr1219352489+29301170381792584
ENST00000602281DISC1chr1231837770-ENST00000366927LYPLAL1chr1219352489+28821170381744568
ENST00000539444DISC1chr1231837770-ENST00000366928LYPLAL1chr1219352489+29301170381792584
ENST00000539444DISC1chr1231837770-ENST00000366927LYPLAL1chr1219352489+28821170381744568
ENST00000366633DISC1chr1231837770-ENST00000366928LYPLAL1chr1219352489+29301170381792584
ENST00000366633DISC1chr1231837770-ENST00000366927LYPLAL1chr1219352489+28821170381744568
ENST00000366636DISC1chr1231837770-ENST00000366928LYPLAL1chr1219352489+29301170381792584
ENST00000366636DISC1chr1231837770-ENST00000366927LYPLAL1chr1219352489+28821170381744568
ENST00000535983DISC1chr1231837770-ENST00000366928LYPLAL1chr1219352489+29301170381792584
ENST00000535983DISC1chr1231837770-ENST00000366927LYPLAL1chr1219352489+28821170381744568
ENST00000537876DISC1chr1231837770-ENST00000366928LYPLAL1chr1219352489+29301170381792584
ENST00000537876DISC1chr1231837770-ENST00000366927LYPLAL1chr1219352489+28821170381744568
ENST00000439617DISC1chr1231837770-ENST00000366928LYPLAL1chr1219352489+29301170381792584
ENST00000439617DISC1chr1231837770-ENST00000366927LYPLAL1chr1219352489+28821170381744568

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000602281ENST00000366928DISC1chr1231837770-LYPLAL1chr1219352489+0.0105357050.9894643
ENST00000602281ENST00000366927DISC1chr1231837770-LYPLAL1chr1219352489+0.0117640260.9882359
ENST00000539444ENST00000366928DISC1chr1231837770-LYPLAL1chr1219352489+0.0105357050.9894643
ENST00000539444ENST00000366927DISC1chr1231837770-LYPLAL1chr1219352489+0.0117640260.9882359
ENST00000366633ENST00000366928DISC1chr1231837770-LYPLAL1chr1219352489+0.0105357050.9894643
ENST00000366633ENST00000366927DISC1chr1231837770-LYPLAL1chr1219352489+0.0117640260.9882359
ENST00000366636ENST00000366928DISC1chr1231837770-LYPLAL1chr1219352489+0.0105357050.9894643
ENST00000366636ENST00000366927DISC1chr1231837770-LYPLAL1chr1219352489+0.0117640260.9882359
ENST00000535983ENST00000366928DISC1chr1231837770-LYPLAL1chr1219352489+0.0105357050.9894643
ENST00000535983ENST00000366927DISC1chr1231837770-LYPLAL1chr1219352489+0.0117640260.9882359
ENST00000537876ENST00000366928DISC1chr1231837770-LYPLAL1chr1219352489+0.0105357050.9894643
ENST00000537876ENST00000366927DISC1chr1231837770-LYPLAL1chr1219352489+0.0117640260.9882359
ENST00000439617ENST00000366928DISC1chr1231837770-LYPLAL1chr1219352489+0.0105357050.9894643
ENST00000439617ENST00000366927DISC1chr1231837770-LYPLAL1chr1219352489+0.0117640260.9882359

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Fusion Genomic Features for DISC1-LYPLAL1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for DISC1-LYPLAL1


check button Go to

FGviewer for the breakpoints of chr1:231837770-chr1:219352489

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DISC1

Q9NRI5

LYPLAL1

Q5VWZ2

FUNCTION: Involved in the regulation of multiple aspects of embryonic and adult neurogenesis (PubMed:19502360, PubMed:19303846). Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus (By similarity). Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance (PubMed:19303846). Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including neuron positioning, dendritic development and synapse formation (By similarity). Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A (By similarity). Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development (PubMed:19502360). Inhibits ATF4 transcription factor activity in neurons by disrupting ATF4 dimerization and DNA-binding (By similarity). Plays a role, together with PCNT, in the microtubule network formation (PubMed:18955030). {ECO:0000250|UniProtKB:Q811T9, ECO:0000269|PubMed:18955030, ECO:0000269|PubMed:19303846, ECO:0000269|PubMed:19502360}.FUNCTION: Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site. {ECO:0000269|PubMed:22052940, ECO:0000269|PubMed:22399288}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDISC1chr1:231837770chr1:219352489ENST00000317586-13366_3940370.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000317586-13452_5050370.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000317586-13602_6660370.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000317586-13802_8300370.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000366633-310366_394372.3333333333333756.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000366633-310452_505372.3333333333333756.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000366633-310602_666372.3333333333333756.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000366633-310802_830372.3333333333333756.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000366636-310366_394372.3333333333333679.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000366636-310452_505372.3333333333333679.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000366636-310602_666372.3333333333333679.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000366636-310802_830372.3333333333333679.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000535983-310366_394372.3333333333333696.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000535983-310452_505372.3333333333333696.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000535983-310602_666372.3333333333333696.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000535983-310802_830372.3333333333333696.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000537876-38366_394372.3333333333333809.3333333333334Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000537876-38452_505372.3333333333333809.3333333333334Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000537876-38602_666372.3333333333333809.3333333333334Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000537876-38802_830372.3333333333333809.3333333333334Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000539444-38366_394372.3333333333333580.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000539444-38452_505372.3333333333333580.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000539444-38602_666372.3333333333333580.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000539444-38802_830372.3333333333333580.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000602281-39366_394372.3333333333333663.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000602281-39452_505372.3333333333333663.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000602281-39602_666372.3333333333333663.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000602281-39802_830372.3333333333333663.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000602873-15366_3940202.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000602873-15452_5050202.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000602873-15602_6660202.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000602873-15802_8300202.0Coiled coilOntology_term=ECO:0000255
HgeneDISC1chr1:231837770chr1:219352489ENST00000317586-13440_5970370.0RegionNote=Required for localization to punctate cytoplasmic foci
HgeneDISC1chr1:231837770chr1:219352489ENST00000366633-310440_597372.3333333333333756.0RegionNote=Required for localization to punctate cytoplasmic foci
HgeneDISC1chr1:231837770chr1:219352489ENST00000366636-310440_597372.3333333333333679.0RegionNote=Required for localization to punctate cytoplasmic foci
HgeneDISC1chr1:231837770chr1:219352489ENST00000535983-310440_597372.3333333333333696.0RegionNote=Required for localization to punctate cytoplasmic foci
HgeneDISC1chr1:231837770chr1:219352489ENST00000537876-38440_597372.3333333333333809.3333333333334RegionNote=Required for localization to punctate cytoplasmic foci
HgeneDISC1chr1:231837770chr1:219352489ENST00000539444-38440_597372.3333333333333580.0RegionNote=Required for localization to punctate cytoplasmic foci
HgeneDISC1chr1:231837770chr1:219352489ENST00000602281-39440_597372.3333333333333663.0RegionNote=Required for localization to punctate cytoplasmic foci
HgeneDISC1chr1:231837770chr1:219352489ENST00000602873-15440_5970202.0RegionNote=Required for localization to punctate cytoplasmic foci


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Fusion Gene Sequence for DISC1-LYPLAL1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000602281_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2930nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATCATATACTCCTATGAAAGGAGGAATCTCCAATGTATGGTTTGACAGATTTAAAATAACCAATGACTGCCCAGAACACC
TTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATGAAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAG
GAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAAATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTC
TGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTGTACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGT
TAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTCTAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACC
ATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTACAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATC
AAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTTTTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAA
CACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGTAGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGC
ATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTATTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAAT
ATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTATTTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGA
TATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGTTTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGA
GCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCAATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGAC
AAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAACCCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAA
ATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAATAAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGAT
TAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGATGACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAA
TAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTTTATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACAT
TATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCATTCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCA
ATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTATCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCT

>In-frame_ENST00000602281_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=584AA_start in transcript=38_stop in transcript=1792
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTD
LIDEEVKSGIKKNRILIGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSM

--------------------------------------------------------------
>In-frame_ENST00000602281_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2882nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATTTAAAATAACCAATGACTGCCCAGAACACCTTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATG
AAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAGGAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAA
ATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTCTGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTG
TACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGTTAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTC
TAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACCATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTA
CAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATCAAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTT
TTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAACACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGT
AGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGCATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTA
TTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAATATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTAT
TTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGATATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGT
TTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGAGCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCA
ATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGACAAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAAC
CCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAAATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAAT
AAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGATTAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGAT
GACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAATAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTT
TATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACATTATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCAT
TCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCAATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTA
TCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCTTCCAGTGTGAGGCTGTTTTAAATAAAGCTGCTATGAATATTCATGTAA

>In-frame_ENST00000602281_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=568AA_start in transcript=38_stop in transcript=1744
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRIL
IGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSMLKSLGVTTKFHSFPNV

--------------------------------------------------------------
>In-frame_ENST00000539444_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2930nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATCATATACTCCTATGAAAGGAGGAATCTCCAATGTATGGTTTGACAGATTTAAAATAACCAATGACTGCCCAGAACACC
TTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATGAAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAG
GAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAAATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTC
TGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTGTACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGT
TAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTCTAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACC
ATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTACAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATC
AAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTTTTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAA
CACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGTAGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGC
ATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTATTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAAT
ATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTATTTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGA
TATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGTTTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGA
GCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCAATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGAC
AAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAACCCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAA
ATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAATAAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGAT
TAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGATGACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAA
TAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTTTATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACAT
TATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCATTCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCA
ATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTATCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCT

>In-frame_ENST00000539444_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=584AA_start in transcript=38_stop in transcript=1792
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTD
LIDEEVKSGIKKNRILIGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSM

--------------------------------------------------------------
>In-frame_ENST00000539444_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2882nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATTTAAAATAACCAATGACTGCCCAGAACACCTTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATG
AAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAGGAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAA
ATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTCTGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTG
TACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGTTAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTC
TAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACCATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTA
CAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATCAAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTT
TTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAACACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGT
AGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGCATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTA
TTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAATATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTAT
TTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGATATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGT
TTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGAGCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCA
ATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGACAAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAAC
CCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAAATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAAT
AAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGATTAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGAT
GACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAATAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTT
TATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACATTATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCAT
TCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCAATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTA
TCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCTTCCAGTGTGAGGCTGTTTTAAATAAAGCTGCTATGAATATTCATGTAA

>In-frame_ENST00000539444_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=568AA_start in transcript=38_stop in transcript=1744
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRIL
IGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSMLKSLGVTTKFHSFPNV

--------------------------------------------------------------
>In-frame_ENST00000366633_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2930nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATCATATACTCCTATGAAAGGAGGAATCTCCAATGTATGGTTTGACAGATTTAAAATAACCAATGACTGCCCAGAACACC
TTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATGAAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAG
GAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAAATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTC
TGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTGTACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGT
TAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTCTAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACC
ATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTACAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATC
AAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTTTTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAA
CACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGTAGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGC
ATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTATTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAAT
ATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTATTTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGA
TATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGTTTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGA
GCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCAATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGAC
AAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAACCCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAA
ATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAATAAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGAT
TAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGATGACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAA
TAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTTTATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACAT
TATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCATTCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCA
ATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTATCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCT

>In-frame_ENST00000366633_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=584AA_start in transcript=38_stop in transcript=1792
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTD
LIDEEVKSGIKKNRILIGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSM

--------------------------------------------------------------
>In-frame_ENST00000366633_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2882nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATTTAAAATAACCAATGACTGCCCAGAACACCTTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATG
AAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAGGAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAA
ATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTCTGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTG
TACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGTTAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTC
TAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACCATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTA
CAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATCAAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTT
TTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAACACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGT
AGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGCATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTA
TTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAATATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTAT
TTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGATATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGT
TTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGAGCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCA
ATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGACAAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAAC
CCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAAATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAAT
AAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGATTAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGAT
GACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAATAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTT
TATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACATTATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCAT
TCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCAATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTA
TCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCTTCCAGTGTGAGGCTGTTTTAAATAAAGCTGCTATGAATATTCATGTAA

>In-frame_ENST00000366633_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=568AA_start in transcript=38_stop in transcript=1744
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRIL
IGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSMLKSLGVTTKFHSFPNV

--------------------------------------------------------------
>In-frame_ENST00000366636_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2930nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATCATATACTCCTATGAAAGGAGGAATCTCCAATGTATGGTTTGACAGATTTAAAATAACCAATGACTGCCCAGAACACC
TTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATGAAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAG
GAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAAATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTC
TGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTGTACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGT
TAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTCTAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACC
ATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTACAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATC
AAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTTTTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAA
CACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGTAGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGC
ATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTATTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAAT
ATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTATTTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGA
TATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGTTTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGA
GCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCAATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGAC
AAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAACCCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAA
ATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAATAAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGAT
TAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGATGACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAA
TAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTTTATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACAT
TATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCATTCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCA
ATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTATCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCT

>In-frame_ENST00000366636_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=584AA_start in transcript=38_stop in transcript=1792
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTD
LIDEEVKSGIKKNRILIGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSM

--------------------------------------------------------------
>In-frame_ENST00000366636_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2882nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATTTAAAATAACCAATGACTGCCCAGAACACCTTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATG
AAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAGGAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAA
ATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTCTGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTG
TACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGTTAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTC
TAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACCATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTA
CAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATCAAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTT
TTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAACACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGT
AGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGCATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTA
TTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAATATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTAT
TTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGATATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGT
TTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGAGCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCA
ATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGACAAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAAC
CCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAAATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAAT
AAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGATTAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGAT
GACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAATAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTT
TATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACATTATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCAT
TCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCAATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTA
TCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCTTCCAGTGTGAGGCTGTTTTAAATAAAGCTGCTATGAATATTCATGTAA

>In-frame_ENST00000366636_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=568AA_start in transcript=38_stop in transcript=1744
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRIL
IGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSMLKSLGVTTKFHSFPNV

--------------------------------------------------------------
>In-frame_ENST00000535983_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2930nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATCATATACTCCTATGAAAGGAGGAATCTCCAATGTATGGTTTGACAGATTTAAAATAACCAATGACTGCCCAGAACACC
TTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATGAAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAG
GAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAAATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTC
TGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTGTACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGT
TAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTCTAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACC
ATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTACAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATC
AAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTTTTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAA
CACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGTAGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGC
ATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTATTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAAT
ATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTATTTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGA
TATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGTTTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGA
GCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCAATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGAC
AAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAACCCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAA
ATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAATAAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGAT
TAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGATGACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAA
TAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTTTATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACAT
TATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCATTCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCA
ATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTATCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCT

>In-frame_ENST00000535983_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=584AA_start in transcript=38_stop in transcript=1792
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTD
LIDEEVKSGIKKNRILIGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSM

--------------------------------------------------------------
>In-frame_ENST00000535983_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2882nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATTTAAAATAACCAATGACTGCCCAGAACACCTTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATG
AAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAGGAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAA
ATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTCTGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTG
TACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGTTAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTC
TAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACCATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTA
CAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATCAAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTT
TTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAACACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGT
AGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGCATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTA
TTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAATATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTAT
TTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGATATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGT
TTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGAGCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCA
ATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGACAAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAAC
CCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAAATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAAT
AAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGATTAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGAT
GACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAATAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTT
TATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACATTATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCAT
TCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCAATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTA
TCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCTTCCAGTGTGAGGCTGTTTTAAATAAAGCTGCTATGAATATTCATGTAA

>In-frame_ENST00000535983_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=568AA_start in transcript=38_stop in transcript=1744
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRIL
IGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSMLKSLGVTTKFHSFPNV

--------------------------------------------------------------
>In-frame_ENST00000537876_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2930nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATCATATACTCCTATGAAAGGAGGAATCTCCAATGTATGGTTTGACAGATTTAAAATAACCAATGACTGCCCAGAACACC
TTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATGAAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAG
GAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAAATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTC
TGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTGTACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGT
TAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTCTAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACC
ATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTACAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATC
AAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTTTTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAA
CACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGTAGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGC
ATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTATTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAAT
ATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTATTTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGA
TATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGTTTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGA
GCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCAATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGAC
AAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAACCCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAA
ATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAATAAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGAT
TAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGATGACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAA
TAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTTTATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACAT
TATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCATTCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCA
ATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTATCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCT

>In-frame_ENST00000537876_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=584AA_start in transcript=38_stop in transcript=1792
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTD
LIDEEVKSGIKKNRILIGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSM

--------------------------------------------------------------
>In-frame_ENST00000537876_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2882nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATTTAAAATAACCAATGACTGCCCAGAACACCTTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATG
AAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAGGAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAA
ATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTCTGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTG
TACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGTTAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTC
TAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACCATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTA
CAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATCAAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTT
TTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAACACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGT
AGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGCATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTA
TTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAATATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTAT
TTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGATATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGT
TTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGAGCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCA
ATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGACAAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAAC
CCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAAATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAAT
AAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGATTAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGAT
GACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAATAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTT
TATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACATTATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCAT
TCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCAATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTA
TCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCTTCCAGTGTGAGGCTGTTTTAAATAAAGCTGCTATGAATATTCATGTAA

>In-frame_ENST00000537876_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=568AA_start in transcript=38_stop in transcript=1744
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRIL
IGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSMLKSLGVTTKFHSFPNV

--------------------------------------------------------------
>In-frame_ENST00000439617_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2930nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATCATATACTCCTATGAAAGGAGGAATCTCCAATGTATGGTTTGACAGATTTAAAATAACCAATGACTGCCCAGAACACC
TTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATGAAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAG
GAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAAATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTC
TGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTGTACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGT
TAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTCTAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACC
ATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTACAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATC
AAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTTTTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAA
CACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGTAGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGC
ATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTATTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAAT
ATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTATTTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGA
TATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGTTTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGA
GCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCAATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGAC
AAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAACCCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAA
ATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAATAAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGAT
TAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGATGACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAA
TAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTTTATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACAT
TATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCATTCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCA
ATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTATCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCT

>In-frame_ENST00000439617_ENST00000366928_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=584AA_start in transcript=38_stop in transcript=1792
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTD
LIDEEVKSGIKKNRILIGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSM

--------------------------------------------------------------
>In-frame_ENST00000439617_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(transcript)=2882nt_BP=1170nt
GGAAGGAGCAGGAGGCAGCCCAGGCGGAGCGGGAGGAGCTGGCAGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCG
CCGGCGGCGGCGGCGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGGC
CGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTG
GCGAGGAGTCCCACCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGTG
CAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTA
GCTGGCCGTGTGGCCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCAG
CCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCC
CTGAGGTCCCCCCAACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAAC
GTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGG
ACGGGCCTCACGAGGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCCGCAAGGA
ACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTG
GTGGTGATGGGAGCAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGCCTGCTGA
GAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAG
GTGATTCTGGACAAGGATTAAGAATGTGGATCAAGCAGGTTTTAAATCAAGATTTAACATTCCAACACATAAAAATTATTTATCCAACAG
CTCCTCCCAGATTTAAAATAACCAATGACTGCCCAGAACACCTTGAATCAATTGATGTCATGTGTCAAGTGCTTACTGATTTGATTGATG
AAGAAGTAAAAAGTGGCATCAAGAAGAACAGGATATTAATAGGAGGATTCTCTATGGGAGGATGCATGGCAATACATTTAGCATATAGAA
ATCATCAAGATGTGGCAGGAGTATTTGCTCTTTCTAGTTTTCTGAATAAAGCATCTGCTGTTTACCAGGCTCTTCAGAAGAGTAATGGTG
TACTTCCTGAATTATTTCAGTGTCATGGTACTGCAGATGAGTTAGTTCTTCATTCTTGGGCAGAAGAGACAAACTCAATGTTAAAATCTC
TAGGAGTGACCACGAAGTTTCATAGTTTTCCAAATGTTTACCATGAGCTAAGCAAAACTGAGTTAGACATATTGAAGTTATGGATTCTTA
CAAAGCTGCCAGGAGAAATGGAAAAACAAAAATGAATGAATCAAGAGTGATTTGTTAATGTAAGTGTAATGTCTTTGTGAAAAGTGATTT
TTACTGCCAAATTATAATGATAATTAAAATATTAAGAAATAACACTTTCCTGACTTTTTTATTATTAAAATGCTTATCACTGTAGACAGT
AGCTAATCTTATTAATGAAAAACAATAGACAAACATCTGTGCATAATTTTTCAGACACAATTCTGTAAATATTTGGAAACCTTTTAAGTA
TTTAAACTTTTAAATTTTTGAAATAAAGTATTCTAAACTAATATAAATAAGGACAATGAAAAAACATGAAAGGACTTAGCATAATGTTAT
TTTATCTTTTCTACAACTTTGTTTAAATTACCTTTCCAAAGATATTTGTGTTTATGTAATTTTCCACGGAATAACATTAATACTCTAGGT
TTATAAACCGGTTTCACATTATTTCATTTGATCATCACAAGAGCTTTGTGAAGTAAGCCGAGAAGTTGTTACTGGTATTTAATAATAGCA
ATAGAGGAGTTAAAGACTTTCCCACAGCTTGCAGGTCAAGACAAGAAATTCAGGTCTCCTAATTCTCAGTGGAGCTCTATTTCTGTTAAC
CCAAATTGCTGCTCTGTTTTAGGTCTCAATTTCATCTGTAAAATGATACTAATAGTACTTATCCCATTGGATTTTTGTTGAGATTTAAAT
AAATAGCCAAAAGCCAATACATAATAAACACTCAATAAAGATTAACCATAAGGAGAGTCATGATCTGGTTCCAGGAATACATTGTTAGAT
GACTGAAAAATTGTATTACTTCAATGAAAATACTATAAATAATAACATTTTCATATATTAGTTGGTTCTCATGCATACATAATCTAATTT
TATTTGATCCTCACAACTGTTTAAGTTTTATTAAATATACATTATCCCTATTTGTATAAATAGAATCATACAATACCTGCCTGCTTTCAT
TCAACAAAATTATCATGAGATTTTTCCATGTTGTGTACATCAATAGTTCATCTATTTTATTGCTCAGTAATATTCCATTGTGTGGATGTA
TCACTATTTGTTTACACATTCACCACTGATATATAAGTTGCTTCCAGTGTGAGGCTGTTTTAAATAAAGCTGCTATGAATATTCATGTAA

>In-frame_ENST00000439617_ENST00000366927_TCGA-AF-4110-01A_DISC1_chr1_231837770_-_LYPLAL1_chr1_219352489_length(amino acids)=568AA_start in transcript=38_stop in transcript=1744
MAAGRMPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQ
CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAG
SLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRP
FSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL
KLQKLQEDAVENDDYDKGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRIL
IGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSMLKSLGVTTKFHSFPNV

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Fusion Gene PPI Analysis for DISC1-LYPLAL1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneDISC1chr1:231837770chr1:219352489ENST00000366633-3101_292372.3333333333333756.0MAP1A
HgeneDISC1chr1:231837770chr1:219352489ENST00000366636-3101_292372.3333333333333679.0MAP1A
HgeneDISC1chr1:231837770chr1:219352489ENST00000535983-3101_292372.3333333333333696.0MAP1A
HgeneDISC1chr1:231837770chr1:219352489ENST00000537876-381_292372.3333333333333809.3333333333334MAP1A
HgeneDISC1chr1:231837770chr1:219352489ENST00000539444-381_292372.3333333333333580.0MAP1A
HgeneDISC1chr1:231837770chr1:219352489ENST00000602281-391_292372.3333333333333663.0MAP1A


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneDISC1chr1:231837770chr1:219352489ENST00000317586-13598_8540370.0ATF4 and ATF5
HgeneDISC1chr1:231837770chr1:219352489ENST00000366633-310598_854372.3333333333333756.0ATF4 and ATF5
HgeneDISC1chr1:231837770chr1:219352489ENST00000366636-310598_854372.3333333333333679.0ATF4 and ATF5
HgeneDISC1chr1:231837770chr1:219352489ENST00000535983-310598_854372.3333333333333696.0ATF4 and ATF5
HgeneDISC1chr1:231837770chr1:219352489ENST00000537876-38598_854372.3333333333333809.3333333333334ATF4 and ATF5
HgeneDISC1chr1:231837770chr1:219352489ENST00000539444-38598_854372.3333333333333580.0ATF4 and ATF5
HgeneDISC1chr1:231837770chr1:219352489ENST00000602281-39598_854372.3333333333333663.0ATF4 and ATF5
HgeneDISC1chr1:231837770chr1:219352489ENST00000602873-15598_8540202.0ATF4 and ATF5
HgeneDISC1chr1:231837770chr1:219352489ENST00000317586-131_2920370.0MAP1A
HgeneDISC1chr1:231837770chr1:219352489ENST00000602873-151_2920202.0MAP1A
HgeneDISC1chr1:231837770chr1:219352489ENST00000317586-13802_8350370.0NDEL1
HgeneDISC1chr1:231837770chr1:219352489ENST00000366633-310802_835372.3333333333333756.0NDEL1
HgeneDISC1chr1:231837770chr1:219352489ENST00000366636-310802_835372.3333333333333679.0NDEL1
HgeneDISC1chr1:231837770chr1:219352489ENST00000535983-310802_835372.3333333333333696.0NDEL1
HgeneDISC1chr1:231837770chr1:219352489ENST00000537876-38802_835372.3333333333333809.3333333333334NDEL1
HgeneDISC1chr1:231837770chr1:219352489ENST00000539444-38802_835372.3333333333333580.0NDEL1
HgeneDISC1chr1:231837770chr1:219352489ENST00000602281-39802_835372.3333333333333663.0NDEL1
HgeneDISC1chr1:231837770chr1:219352489ENST00000602873-15802_8350202.0NDEL1
HgeneDISC1chr1:231837770chr1:219352489ENST00000317586-13727_8540370.0PAFAH1B1
HgeneDISC1chr1:231837770chr1:219352489ENST00000366633-310727_854372.3333333333333756.0PAFAH1B1
HgeneDISC1chr1:231837770chr1:219352489ENST00000366636-310727_854372.3333333333333679.0PAFAH1B1
HgeneDISC1chr1:231837770chr1:219352489ENST00000535983-310727_854372.3333333333333696.0PAFAH1B1
HgeneDISC1chr1:231837770chr1:219352489ENST00000537876-38727_854372.3333333333333809.3333333333334PAFAH1B1
HgeneDISC1chr1:231837770chr1:219352489ENST00000539444-38727_854372.3333333333333580.0PAFAH1B1
HgeneDISC1chr1:231837770chr1:219352489ENST00000602281-39727_854372.3333333333333663.0PAFAH1B1
HgeneDISC1chr1:231837770chr1:219352489ENST00000602873-15727_8540202.0PAFAH1B1
HgeneDISC1chr1:231837770chr1:219352489ENST00000317586-13293_6960370.0TRAF3IP1
HgeneDISC1chr1:231837770chr1:219352489ENST00000366633-310293_696372.3333333333333756.0TRAF3IP1
HgeneDISC1chr1:231837770chr1:219352489ENST00000366636-310293_696372.3333333333333679.0TRAF3IP1
HgeneDISC1chr1:231837770chr1:219352489ENST00000535983-310293_696372.3333333333333696.0TRAF3IP1
HgeneDISC1chr1:231837770chr1:219352489ENST00000537876-38293_696372.3333333333333809.3333333333334TRAF3IP1
HgeneDISC1chr1:231837770chr1:219352489ENST00000539444-38293_696372.3333333333333580.0TRAF3IP1
HgeneDISC1chr1:231837770chr1:219352489ENST00000602281-39293_696372.3333333333333663.0TRAF3IP1
HgeneDISC1chr1:231837770chr1:219352489ENST00000602873-15293_6960202.0TRAF3IP1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DISC1-LYPLAL1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DISC1-LYPLAL1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneDISC1C0011581Depressive disorder6CTD_human;PSYGENET
HgeneDISC1C0041696Unipolar Depression6CTD_human;PSYGENET
HgeneDISC1C0005586Bipolar Disorder5PSYGENET
HgeneDISC1C0011570Mental Depression5PSYGENET
HgeneDISC1C0525045Mood Disorders5PSYGENET
HgeneDISC1C1269683Major Depressive Disorder5PSYGENET
HgeneDISC1C0004352Autistic Disorder2CTD_human
HgeneDISC1C0036341Schizophrenia2CTD_human
HgeneDISC1C0003469Anxiety Disorders1CTD_human
HgeneDISC1C0005587Depression, Bipolar1PSYGENET
HgeneDISC1C0011573Endogenous depression1CTD_human
HgeneDISC1C0011757Developmental Coordination Disorder1CTD_human
HgeneDISC1C0020796Profound Mental Retardation1CTD_human
HgeneDISC1C0025193Melancholia1CTD_human
HgeneDISC1C0025363Mental Retardation, Psychosocial1CTD_human
HgeneDISC1C0026613Motor Skills Disorders1CTD_human
HgeneDISC1C0030193Pain1CTD_human
HgeneDISC1C0086133Depressive Syndrome1CTD_human
HgeneDISC1C0178417Anhedonia1PSYGENET
HgeneDISC1C0234230Pain, Burning1CTD_human
HgeneDISC1C0234238Ache1CTD_human
HgeneDISC1C0234254Radiating pain1CTD_human
HgeneDISC1C0236792Asperger Syndrome1CTD_human
HgeneDISC1C0282126Depression, Neurotic1CTD_human
HgeneDISC1C0376280Anxiety States, Neurotic1CTD_human
HgeneDISC1C0458257Pain, Splitting1CTD_human
HgeneDISC1C0458259Pain, Crushing1CTD_human
HgeneDISC1C0751217Hyperkinesia, Generalized1CTD_human
HgeneDISC1C0751407Pain, Migratory1CTD_human
HgeneDISC1C0751408Suffering, Physical1CTD_human
HgeneDISC1C0917816Mental deficiency1CTD_human
HgeneDISC1C1279420Anxiety neurosis (finding)1CTD_human
HgeneDISC1C3714756Intellectual Disability1CTD_human
HgeneDISC1C3887506Hyperkinesia1CTD_human