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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DNAH1-PRKCD (FusionGDB2 ID:23301)

Fusion Gene Summary for DNAH1-PRKCD

check button Fusion gene summary
Fusion gene informationFusion gene name: DNAH1-PRKCD
Fusion gene ID: 23301
HgeneTgene
Gene symbol

DNAH1

PRKCD

Gene ID

25981

5580

Gene namedynein axonemal heavy chain 1protein kinase C delta
SynonymsCILD37|DNAHC1|HDHC7|HL-11|HL11|HSRF-1|SPGF18|XLHSRF-1ALPS3|CVID9|MAY1|PKCD|nPKC-delta
Cytomap

3p21.1

3p21.1

Type of geneprotein-codingprotein-coding
Descriptiondynein heavy chain 1, axonemalaxonemal beta dynein heavy chain 1ciliary dynein heavy chain 1dynein, axonemal, heavy polypeptide 1heat shock regulated protein 1testicular tissue protein Li 60protein kinase C delta typeprotein kinase C delta VIIItyrosine-protein kinase PRKCD
Modification date2020032020200313
UniProtAcc

Q9P2D7

.
Ensembl transtripts involved in fusion geneENST00000420323, ENST00000466628, 
ENST00000394729, ENST00000330452, 
ENST00000477794, 
Fusion gene scores* DoF score6 X 6 X 4=1447 X 7 X 5=245
# samples 67
** MAII scorelog2(6/144*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/245*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DNAH1 [Title/Abstract] AND PRKCD [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDNAH1(52391751)-PRKCD(53221356), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDNAH1

GO:0036159

inner dynein arm assembly

24360805

TgenePRKCD

GO:0006468

protein phosphorylation

10713049|16611985

TgenePRKCD

GO:0006915

apoptotic process

10770950

TgenePRKCD

GO:0016572

histone phosphorylation

19059439

TgenePRKCD

GO:0018105

peptidyl-serine phosphorylation

18285462

TgenePRKCD

GO:0018107

peptidyl-threonine phosphorylation

10770950

TgenePRKCD

GO:0032147

activation of protein kinase activity

10713049

TgenePRKCD

GO:0042119

neutrophil activation

10770950

TgenePRKCD

GO:0070301

cellular response to hydrogen peroxide

10713049

TgenePRKCD

GO:0071447

cellular response to hydroperoxide

19059439

TgenePRKCD

GO:1904385

cellular response to angiotensin

18285462


check buttonFusion gene breakpoints across DNAH1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PRKCD (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1603-01ADNAH1chr3

52391751

+PRKCDchr3

53221356

+
ChimerDB4OVTCGA-24-1603-01ADNAH1chr3

52391751

+PRKCDchr3

53221356

+


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Fusion Gene ORF analysis for DNAH1-PRKCD

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000420323ENST00000394729DNAH1chr3

52391751

+PRKCDchr3

53221356

+
In-frameENST00000420323ENST00000330452DNAH1chr3

52391751

+PRKCDchr3

53221356

+
5CDS-intronENST00000420323ENST00000477794DNAH1chr3

52391751

+PRKCDchr3

53221356

+
intron-3CDSENST00000466628ENST00000394729DNAH1chr3

52391751

+PRKCDchr3

53221356

+
intron-3CDSENST00000466628ENST00000330452DNAH1chr3

52391751

+PRKCDchr3

53221356

+
intron-intronENST00000466628ENST00000477794DNAH1chr3

52391751

+PRKCDchr3

53221356

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000420323DNAH1chr352391751+ENST00000394729PRKCDchr353221356+5371424118649191577
ENST00000420323DNAH1chr352391751+ENST00000330452PRKCDchr353221356+5208424118649191577

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000420323ENST00000394729DNAH1chr352391751+PRKCDchr353221356+0.0025835720.9974164
ENST00000420323ENST00000330452DNAH1chr352391751+PRKCDchr353221356+0.0032298340.99677014

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Fusion Genomic Features for DNAH1-PRKCD


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DNAH1chr352391751+PRKCDchr353221355+0.0015648350.9984352
DNAH1chr352391751+PRKCDchr353221355+0.0015648350.9984352

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for DNAH1-PRKCD


check button Go to

FGviewer for the breakpoints of chr3:52391751-chr3:53221356

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DNAH1

Q9P2D7

.
FUNCTION: Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme (PubMed:24360805). {ECO:0000250|UniProtKB:Q91XQ0, ECO:0000269|PubMed:24360805}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePRKCDchr3:52391751chr3:53221356ENST000003304521319604_675450.6666666666667677.0DomainAGC-kinase C-terminal
TgenePRKCDchr3:52391751chr3:53221356ENST000003947291218604_675450.6666666666667677.0DomainAGC-kinase C-terminal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23783074_31221326.66666666666674266.0Coiled coilOntology_term=ECO:0000255
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23782167_21721326.66666666666674266.0Compositional biasNote=Poly-Glu
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23781581_15881326.66666666666674266.0MotifNote=GPAGTGKT motif
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23781631_16371326.66666666666674266.0MotifNote=CFDEFNR motif
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23781862_18691326.66666666666674266.0Nucleotide bindingATP
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23782227_22341326.66666666666674266.0Nucleotide bindingATP
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23782586_25931326.66666666666674266.0Nucleotide bindingATP
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23781543_17641326.66666666666674266.0RegionAAA 1
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23781824_20571326.66666666666674266.0RegionAAA 2
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23781_15421326.66666666666674266.0RegionStem
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23782189_24491326.66666666666674266.0RegionAAA 3
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23782547_27991326.66666666666674266.0RegionAAA 4
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23782814_31121326.66666666666674266.0RegionStalk
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23783197_34271326.66666666666674266.0RegionAAA 5
HgeneDNAH1chr3:52391751chr3:53221356ENST00000420323+23783640_38591326.66666666666674266.0RegionAAA 6
TgenePRKCDchr3:52391751chr3:53221356ENST0000033045213191_106450.6666666666667677.0DomainC2
TgenePRKCDchr3:52391751chr3:53221356ENST000003304521319349_603450.6666666666667677.0DomainProtein kinase
TgenePRKCDchr3:52391751chr3:53221356ENST0000039472912181_106450.6666666666667677.0DomainC2
TgenePRKCDchr3:52391751chr3:53221356ENST000003947291218349_603450.6666666666667677.0DomainProtein kinase
TgenePRKCDchr3:52391751chr3:53221356ENST000003304521319355_363450.6666666666667677.0Nucleotide bindingATP
TgenePRKCDchr3:52391751chr3:53221356ENST000003947291218355_363450.6666666666667677.0Nucleotide bindingATP
TgenePRKCDchr3:52391751chr3:53221356ENST000003304521319158_208450.6666666666667677.0Zinc fingerPhorbol-ester/DAG-type 1
TgenePRKCDchr3:52391751chr3:53221356ENST000003304521319230_280450.6666666666667677.0Zinc fingerPhorbol-ester/DAG-type 2
TgenePRKCDchr3:52391751chr3:53221356ENST000003947291218158_208450.6666666666667677.0Zinc fingerPhorbol-ester/DAG-type 1
TgenePRKCDchr3:52391751chr3:53221356ENST000003947291218230_280450.6666666666667677.0Zinc fingerPhorbol-ester/DAG-type 2


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Fusion Gene Sequence for DNAH1-PRKCD


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000420323_ENST00000394729_TCGA-24-1603-01A_DNAH1_chr3_52391751_+_PRKCD_chr3_53221356_length(transcript)=5371nt_BP=4241nt
GGGGGGTACCCAACCTATACGCAGACCCATTGAGCAGCCAGACTGCCCTAAACAGGGCTATGGAGTCCTTGTCCCTTCTAAGAGCTGTGG
ACACCTTGCCTCCAGTTCCCCTCACAGTCCTTTCTTCCTTCTGCAGTGATCACTGAGTACCTGTGTGAATGCCAACAAGAAAAATAAAAC
CACAGTTTGGATTCAGGAAAGGTTGCACCACCATCAGGTCTTGAAGGGAGCTTCGGCTGGGGCATCTCCCTGAGAAGCAGCATGGAGCAG
CCTAACAGTAAAGGCTATAGCCTGGGAAGGACCCCTCAGGGCCCAGAGTGCAGCAGTGCTCCTGCAGTCCAAGTGGGGACCCACAGGGGC
CTAGAGTATAACCCGGGGAAGATTCTTCCAGGATCAGACTATGGGTTGGGAAATCCTCCAGCCCTTGACCCCAAGCTCCCACATTTACCC
CTGCCCCCGGCCCCACCCACACTCTCAGACTTGGGGCAGCCACGGAAGTCACCCCTGACAGGCACTGATAAGAAGTACCCGCTGATGAAG
CAGCGTGGGTTCTACTCCGACATCCTCAGCCCTGGAACCTTAGATCAACTTGGGGAGGTATGTCGTGGCCCCCGAATGAGCCAGAACCTC
CTGCGGCAGGCTGACCTTGACAAGTTCACCCCAAGAGTCGGAAGCTTTGAGGTTCCTGAAGACTTCCAGGAGCGCATGGAGCAGCAGTGC
ATCGGGTCCACCACCCGGCTGCTCGCCCAGACTGACTTCCCACTGCAGGCCTACGAGCCCAAGATGCAGGTGCCTTTCCAGGTGCTGCCA
GGCCAGCATCCTCGCAAGATTGAGATCGAGAGGAGGAAACAGCAGTACCTGAGCCTGGACATTGAGCAGTTGCTGTTCAGCCAGGGCATC
GACTCCAACAAGCTCATGCCCAGGCACCTGGACCACCAGCACCCCCAAACCATCGAACAGGGCCATGACCCAATCTTCCCCATCTACCTC
CCACTGAAGGTATTTGACAATGAGGACTTTGACTGCCGGACTCCCAGAGAGTGGATCAACATGGGCTTGGAGCCAGGGTCTCTGGACAGG
AAACCTGTCCCGGGAAAAGCCCTCTTGCCCACTGATGACTTCCTGGGGCATGAGGACCCCAAGAGTCAGAAGCTGAAGTACAAATGGTGC
GAGGTCGGCGTCCTGGACTACGACGAGGAGAAGAAGCTATACCTGGTACACAAGACAGACGAGAAAGGCCTGGTGCGAGATGAGATGGGG
AGGCCCATCCTGAATGCAGGGGTCACCACTGAAGGAAGGCCACCCCTTCAGGTCTGTCAGTACTGGGTGCCACGGATCCAGCTTCTCTTC
TGCGCTGAGGACCCTTGCATGTTCGCACAACGTGTGGTCCAGGCCAACGCCCTGCGCAAGAACACGGAAGCACTGCTGCTCTACAACTTG
TATGTGGACTGCATGCCCTCTGACGGCCAGCATGTCATCAGTGAACAGAGCCTGAGCAAGATCAAGCAGTGGGCCCTGAGCACGCCTCGG
ATGCGCAAAGGCCCCTCGGTTCTAGAGCACCTCAGCAGTCTTGCCAGAGAAGTGAGCCTGGACTATGAGCGCAGCATGAACAAGATCAAC
TTTGACCACGTTGTCTCTTCCAAGCCCGAGACCTTCTCCTACGTCACCCTCCCCAAGAAGGAGGAGGAGCAGGTGCCTGAGCGAGGGCTG
GTGAGTGTCCCCAAGTACCACTTCTGGGAGCAGAAGGAGGACTTCACTTTCGTGTCCCTGCTCACACGGCCAGAGGTCATCACGGCCCTC
AGCAAGGTGAGGGCCGAGTGCAACAAGGTGACCGCCATGTCCCTGTTCCACTCGAGCCTCTCCAAGTACAGCCACCTGGAGGAATTTGAG
CAGATCCAGTCACAGACCTTCTCCCAGGTGCAGATGTTCCTCAAGGACAGCTGGATCAGCTCGCTAAAGGTGGCCATGCGCAGCAGCCTG
CGCGACATGAGCAAGGGCTGGTACAACCTCTACGAGACCAACTGGGAGGTGTACCTCATGTCCAAGCTGCGCAAGCTGATGGAGCTGGTG
AAGTACATGCTGCAGGACACACTGCGCTTCCTGGTGCAGGACTCACTTGCCAGCTTCTCACAGTTCATCAGCGACACCTGTTGCAGCGTG
CTCAACTGCACCGATGACATGGTCTGGGGTGACGACTTAATTAACAGCCCCTACAGGCCCCGGAAGAATCCCCTGTTCATCATGGACCTG
GTGCTGGACAGCTCTGGGGTGCACTATAGCACCCCACTGGAGCAGTTTGAGGCATCTCTGCTGAACCTCTTCGACAAGGGCATCCTGGCC
ACCCATGCCGTGCCCCAGCTGGAGAAGCTGGTGATGGAGGACATCTTCATCAGCGGTGACCCCCTGCTGGAGTCCGTGGGCCTTCATGAG
CCACTGGTGGAAGAGCTACGGGCCACCATTGCCAGTGCCGTGTCCAAGGCCATGATCCCACTGCAGGCCTACGCCAAGGAGTACCGAAAG
TACCTGGAGCTGAACAACAATGACATTGCCTCCTTTCTCAAAACCTACCAGACGCAGGGCCTGTTGGCCCAGGAGGTGCGGGAGGTAGTG
CTCACCCACCTGCGGGAGAAGGAGATCCTGGACAGCTCGCTGCCCAGCAGCATCATCATTGGGCCTTTCTACATCAACACCGACAATGTC
AAGCAGAGCCTGTCCAAGAAACGCAAGGCCCTGGCCACTTCCGTGCTGGACATCCTTGCCAAGAACCTGCATAAGGAGGTGGATAGCATC
TGCGAGGAGTTCCGCAGCATCAGCCGCAAGATCTATGAGAAGCCCAACAGCATTGAGGAGCTGGCTGAGCTGCGAGAGTGGATGAAGGGC
ATCCCGGAGAGGCTGGTGGGCCTGGAGGAGCGGATTGTGAAGGTCATGGATGACTACCAGGTCATGGATGAATTCCTCTACAACCTCAGC
TCAGATGACTTCAATGACAAATGGATTGCCAGCAACTGGCCTTCTAAGATCCTTGGGCAGATAGAGCTGGTGCAGCAGCAGCATGTGGAG
GATGAGGAGAAGTTCCGCAAAATCCAGATCATGGATCAGAACAACTTCCAAGAGAAGCTGGAAGGGCTGCAGCTGGTAGTAGCTGGCTTC
TCCATCCATGTGGAGATTTCACGTGCACACGAGATCGCCAACGAGGTGCGGCGTGTCAAGAAGCAGCTGAAGGACTGCCAGCAGCTGGCC
ATGCTCTACAACAACCGCGAGCGCATCTTCAGCTTGCCCATCACCAATTATGACAAGCTCTCCAGGATGGTGAAGGAGTTCCAACCCTAC
CTGGACCTTTGGACCACAGCGTCTGACTGGCTGCGCTGGTCGGAGAGCTGGATGAATGACCCCCTCTCTGCCATCGATGCTGAGCAGCTG
GAGAAGAACGTGGTTGAAGCCTTCAAGACCATGCACAAGTGCGTGAAGCAGTTTAAGGACATGCCAGCCTGCCAGGAAGTGGCCTTGGAC
ATCCGGGCCCGCATCGAGGAGTTCAAACCATACATCCCACTGATCCAGGGGCTGCGCAACCCTGGCATGCGGATCCGGCACTGGGAGACA
CTGTCCAACCAGATCAACATCAATGTCAGGCCCAAGGCCAACCTGACCTTTGCTCGCTGCCTGGAGATGAACCTGCAGGACCATATCGAG
AGCATCAGCAAGGTGGCTGAGGTGGCTGGCAAGGAGTACGCCATCGAGCAGGCACTGGACAAGATGGAGAAGGAGTGGTCGACCATCCTG
TTCAATGTACTGCCCTACAAGGCGACAGACACCTACATCCTGAAGAGCCCGGACGAGGCCTCACAGCTGCTGGACGACCACATCGTCATG
ACCCAGAATATGTCATTTTCACCCTACAAGAAGCCCTTTGAGCAGCGCATCAACTCCTGGGAGAACAAACTGAAGCTGACCCAGGAGGTT
CTGGAGGAGTGGCTGAACTGTCAGCGGTCCTGGCTCTACCTGGAGCCCATCTTTAGCTCTGAGGACATCAACCAGCAGCTGCCTGTGGAG
AGCAAGCGCTACCAGACCATGGAGCGGATCTGGAAGAAGATCATGAAGAATGCCTACGAGAACCGGGAGGTGATCAATGTGTGTTCCGAC
CTGAGAATGCTGGACAGCCTGCGGGACTGCAACAAGATTCTGGACCTGGTGCAGAAGGGCCTCAGCGAGTATCTGGAGACCAAGAGGAGC
GCCTTCCCCAGGTTTTATGCCGCTGAGATAATGTGTGGACTGCAGTTTCTACACAGCAAGGGCATCATTTACAGGGACCTCAAACTGGAC
AATGTGCTGCTGGACCGGGATGGCCACATCAAGATTGCCGACTTTGGGATGTGCAAAGAGAACATATTCGGGGAGAGCCGGGCCAGCACC
TTCTGCGGCACCCCTGACTATATCGCCCCTGAGATCCTACAGGGCCTGAAGTACACATTCTCTGTGGACTGGTGGTCTTTCGGGGTCCTT
CTGTACGAGATGCTCATTGGCCAGTCCCCCTTCCATGGTGATGATGAGGATGAACTCTTCGAGTCCATCCGTGTGGACACGCCACATTAT
CCCCGCTGGATCACCAAGGAGTCCAAGGACATCCTGGAGAAGCTCTTTGAAAGGGAACCAACCAAGAGGCTGGGAGTGACCGGAAACATC
AAAATCCACCCCTTCTTCAAGACCATAAACTGGACTCTGCTGGAAAAGCGGAGGTTGGAGCCACCTTTCAGGCCCAAAGTGAAGTCACCC
AGAGACTACAGTAACTTTGACCAGGAGTTCCTGAACGAGAAGGCGCGCCTCTCCTACAGCGACAAGAACCTCATCGACTCCATGGACCAG
TCTGCATTCGCTGGCTTCTCCTTTGTGAACCCCAAATTCGAGCACCTCCTGGAAGATTGAGGTTCCTGGACAGATCAGGCTAGCCCTGCC
CTCCACCCACACCTGCCCGCTCCCCACGATAAGCACCAGTGGGACTGTGGTGACTTCTGCTGCTGGCCCCGCCCCTGCCCCCAGAGCGTC
CTTGGCTGCCGTCTGGCCGGGCTCTCATGGTACTTCCTCTGTGAACTGTGTGTGAATCTGCTTTTCCTCTGCCTTCGGAGGGAAATTGTA
AATCCTGTGTTTCATTACTTGAATGTAGTTATCTATTGAAAATATATATTATATACATAGACATATATATATATATAATAGGCTGTATAT
ATTGCTCAGTAGAGAAAAACCATGGGGGACTGGTGATATGTTGATCTTTTTCAAAAAAATATATATATGACAAAAAAAAAAAAAAAGGAG

>In-frame_ENST00000420323_ENST00000394729_TCGA-24-1603-01A_DNAH1_chr3_52391751_+_PRKCD_chr3_53221356_length(amino acids)=1577AA_start in transcript=186_stop in transcript=4919
MDSGKVAPPSGLEGSFGWGISLRSSMEQPNSKGYSLGRTPQGPECSSAPAVQVGTHRGLEYNPGKILPGSDYGLGNPPALDPKLPHLPLP
PAPPTLSDLGQPRKSPLTGTDKKYPLMKQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQCIG
STTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQLLFSQGIDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPL
KVFDNEDFDCRTPREWINMGLEPGSLDRKPVPGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRP
ILNAGVTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEALLLYNLYVDCMPSDGQHVISEQSLSKIKQWALSTPRMR
KGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSK
VRAECNKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMELVKY
MLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATH
AVPQLEKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLT
HLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIP
ERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSI
HVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEK
NVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESI
SKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLE
EWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAF
PRFYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLY
EMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLGVTGNIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRD

--------------------------------------------------------------
>In-frame_ENST00000420323_ENST00000330452_TCGA-24-1603-01A_DNAH1_chr3_52391751_+_PRKCD_chr3_53221356_length(transcript)=5208nt_BP=4241nt
GGGGGGTACCCAACCTATACGCAGACCCATTGAGCAGCCAGACTGCCCTAAACAGGGCTATGGAGTCCTTGTCCCTTCTAAGAGCTGTGG
ACACCTTGCCTCCAGTTCCCCTCACAGTCCTTTCTTCCTTCTGCAGTGATCACTGAGTACCTGTGTGAATGCCAACAAGAAAAATAAAAC
CACAGTTTGGATTCAGGAAAGGTTGCACCACCATCAGGTCTTGAAGGGAGCTTCGGCTGGGGCATCTCCCTGAGAAGCAGCATGGAGCAG
CCTAACAGTAAAGGCTATAGCCTGGGAAGGACCCCTCAGGGCCCAGAGTGCAGCAGTGCTCCTGCAGTCCAAGTGGGGACCCACAGGGGC
CTAGAGTATAACCCGGGGAAGATTCTTCCAGGATCAGACTATGGGTTGGGAAATCCTCCAGCCCTTGACCCCAAGCTCCCACATTTACCC
CTGCCCCCGGCCCCACCCACACTCTCAGACTTGGGGCAGCCACGGAAGTCACCCCTGACAGGCACTGATAAGAAGTACCCGCTGATGAAG
CAGCGTGGGTTCTACTCCGACATCCTCAGCCCTGGAACCTTAGATCAACTTGGGGAGGTATGTCGTGGCCCCCGAATGAGCCAGAACCTC
CTGCGGCAGGCTGACCTTGACAAGTTCACCCCAAGAGTCGGAAGCTTTGAGGTTCCTGAAGACTTCCAGGAGCGCATGGAGCAGCAGTGC
ATCGGGTCCACCACCCGGCTGCTCGCCCAGACTGACTTCCCACTGCAGGCCTACGAGCCCAAGATGCAGGTGCCTTTCCAGGTGCTGCCA
GGCCAGCATCCTCGCAAGATTGAGATCGAGAGGAGGAAACAGCAGTACCTGAGCCTGGACATTGAGCAGTTGCTGTTCAGCCAGGGCATC
GACTCCAACAAGCTCATGCCCAGGCACCTGGACCACCAGCACCCCCAAACCATCGAACAGGGCCATGACCCAATCTTCCCCATCTACCTC
CCACTGAAGGTATTTGACAATGAGGACTTTGACTGCCGGACTCCCAGAGAGTGGATCAACATGGGCTTGGAGCCAGGGTCTCTGGACAGG
AAACCTGTCCCGGGAAAAGCCCTCTTGCCCACTGATGACTTCCTGGGGCATGAGGACCCCAAGAGTCAGAAGCTGAAGTACAAATGGTGC
GAGGTCGGCGTCCTGGACTACGACGAGGAGAAGAAGCTATACCTGGTACACAAGACAGACGAGAAAGGCCTGGTGCGAGATGAGATGGGG
AGGCCCATCCTGAATGCAGGGGTCACCACTGAAGGAAGGCCACCCCTTCAGGTCTGTCAGTACTGGGTGCCACGGATCCAGCTTCTCTTC
TGCGCTGAGGACCCTTGCATGTTCGCACAACGTGTGGTCCAGGCCAACGCCCTGCGCAAGAACACGGAAGCACTGCTGCTCTACAACTTG
TATGTGGACTGCATGCCCTCTGACGGCCAGCATGTCATCAGTGAACAGAGCCTGAGCAAGATCAAGCAGTGGGCCCTGAGCACGCCTCGG
ATGCGCAAAGGCCCCTCGGTTCTAGAGCACCTCAGCAGTCTTGCCAGAGAAGTGAGCCTGGACTATGAGCGCAGCATGAACAAGATCAAC
TTTGACCACGTTGTCTCTTCCAAGCCCGAGACCTTCTCCTACGTCACCCTCCCCAAGAAGGAGGAGGAGCAGGTGCCTGAGCGAGGGCTG
GTGAGTGTCCCCAAGTACCACTTCTGGGAGCAGAAGGAGGACTTCACTTTCGTGTCCCTGCTCACACGGCCAGAGGTCATCACGGCCCTC
AGCAAGGTGAGGGCCGAGTGCAACAAGGTGACCGCCATGTCCCTGTTCCACTCGAGCCTCTCCAAGTACAGCCACCTGGAGGAATTTGAG
CAGATCCAGTCACAGACCTTCTCCCAGGTGCAGATGTTCCTCAAGGACAGCTGGATCAGCTCGCTAAAGGTGGCCATGCGCAGCAGCCTG
CGCGACATGAGCAAGGGCTGGTACAACCTCTACGAGACCAACTGGGAGGTGTACCTCATGTCCAAGCTGCGCAAGCTGATGGAGCTGGTG
AAGTACATGCTGCAGGACACACTGCGCTTCCTGGTGCAGGACTCACTTGCCAGCTTCTCACAGTTCATCAGCGACACCTGTTGCAGCGTG
CTCAACTGCACCGATGACATGGTCTGGGGTGACGACTTAATTAACAGCCCCTACAGGCCCCGGAAGAATCCCCTGTTCATCATGGACCTG
GTGCTGGACAGCTCTGGGGTGCACTATAGCACCCCACTGGAGCAGTTTGAGGCATCTCTGCTGAACCTCTTCGACAAGGGCATCCTGGCC
ACCCATGCCGTGCCCCAGCTGGAGAAGCTGGTGATGGAGGACATCTTCATCAGCGGTGACCCCCTGCTGGAGTCCGTGGGCCTTCATGAG
CCACTGGTGGAAGAGCTACGGGCCACCATTGCCAGTGCCGTGTCCAAGGCCATGATCCCACTGCAGGCCTACGCCAAGGAGTACCGAAAG
TACCTGGAGCTGAACAACAATGACATTGCCTCCTTTCTCAAAACCTACCAGACGCAGGGCCTGTTGGCCCAGGAGGTGCGGGAGGTAGTG
CTCACCCACCTGCGGGAGAAGGAGATCCTGGACAGCTCGCTGCCCAGCAGCATCATCATTGGGCCTTTCTACATCAACACCGACAATGTC
AAGCAGAGCCTGTCCAAGAAACGCAAGGCCCTGGCCACTTCCGTGCTGGACATCCTTGCCAAGAACCTGCATAAGGAGGTGGATAGCATC
TGCGAGGAGTTCCGCAGCATCAGCCGCAAGATCTATGAGAAGCCCAACAGCATTGAGGAGCTGGCTGAGCTGCGAGAGTGGATGAAGGGC
ATCCCGGAGAGGCTGGTGGGCCTGGAGGAGCGGATTGTGAAGGTCATGGATGACTACCAGGTCATGGATGAATTCCTCTACAACCTCAGC
TCAGATGACTTCAATGACAAATGGATTGCCAGCAACTGGCCTTCTAAGATCCTTGGGCAGATAGAGCTGGTGCAGCAGCAGCATGTGGAG
GATGAGGAGAAGTTCCGCAAAATCCAGATCATGGATCAGAACAACTTCCAAGAGAAGCTGGAAGGGCTGCAGCTGGTAGTAGCTGGCTTC
TCCATCCATGTGGAGATTTCACGTGCACACGAGATCGCCAACGAGGTGCGGCGTGTCAAGAAGCAGCTGAAGGACTGCCAGCAGCTGGCC
ATGCTCTACAACAACCGCGAGCGCATCTTCAGCTTGCCCATCACCAATTATGACAAGCTCTCCAGGATGGTGAAGGAGTTCCAACCCTAC
CTGGACCTTTGGACCACAGCGTCTGACTGGCTGCGCTGGTCGGAGAGCTGGATGAATGACCCCCTCTCTGCCATCGATGCTGAGCAGCTG
GAGAAGAACGTGGTTGAAGCCTTCAAGACCATGCACAAGTGCGTGAAGCAGTTTAAGGACATGCCAGCCTGCCAGGAAGTGGCCTTGGAC
ATCCGGGCCCGCATCGAGGAGTTCAAACCATACATCCCACTGATCCAGGGGCTGCGCAACCCTGGCATGCGGATCCGGCACTGGGAGACA
CTGTCCAACCAGATCAACATCAATGTCAGGCCCAAGGCCAACCTGACCTTTGCTCGCTGCCTGGAGATGAACCTGCAGGACCATATCGAG
AGCATCAGCAAGGTGGCTGAGGTGGCTGGCAAGGAGTACGCCATCGAGCAGGCACTGGACAAGATGGAGAAGGAGTGGTCGACCATCCTG
TTCAATGTACTGCCCTACAAGGCGACAGACACCTACATCCTGAAGAGCCCGGACGAGGCCTCACAGCTGCTGGACGACCACATCGTCATG
ACCCAGAATATGTCATTTTCACCCTACAAGAAGCCCTTTGAGCAGCGCATCAACTCCTGGGAGAACAAACTGAAGCTGACCCAGGAGGTT
CTGGAGGAGTGGCTGAACTGTCAGCGGTCCTGGCTCTACCTGGAGCCCATCTTTAGCTCTGAGGACATCAACCAGCAGCTGCCTGTGGAG
AGCAAGCGCTACCAGACCATGGAGCGGATCTGGAAGAAGATCATGAAGAATGCCTACGAGAACCGGGAGGTGATCAATGTGTGTTCCGAC
CTGAGAATGCTGGACAGCCTGCGGGACTGCAACAAGATTCTGGACCTGGTGCAGAAGGGCCTCAGCGAGTATCTGGAGACCAAGAGGAGC
GCCTTCCCCAGGTTTTATGCCGCTGAGATAATGTGTGGACTGCAGTTTCTACACAGCAAGGGCATCATTTACAGGGACCTCAAACTGGAC
AATGTGCTGCTGGACCGGGATGGCCACATCAAGATTGCCGACTTTGGGATGTGCAAAGAGAACATATTCGGGGAGAGCCGGGCCAGCACC
TTCTGCGGCACCCCTGACTATATCGCCCCTGAGATCCTACAGGGCCTGAAGTACACATTCTCTGTGGACTGGTGGTCTTTCGGGGTCCTT
CTGTACGAGATGCTCATTGGCCAGTCCCCCTTCCATGGTGATGATGAGGATGAACTCTTCGAGTCCATCCGTGTGGACACGCCACATTAT
CCCCGCTGGATCACCAAGGAGTCCAAGGACATCCTGGAGAAGCTCTTTGAAAGGGAACCAACCAAGAGGCTGGGAGTGACCGGAAACATC
AAAATCCACCCCTTCTTCAAGACCATAAACTGGACTCTGCTGGAAAAGCGGAGGTTGGAGCCACCTTTCAGGCCCAAAGTGAAGTCACCC
AGAGACTACAGTAACTTTGACCAGGAGTTCCTGAACGAGAAGGCGCGCCTCTCCTACAGCGACAAGAACCTCATCGACTCCATGGACCAG
TCTGCATTCGCTGGCTTCTCCTTTGTGAACCCCAAATTCGAGCACCTCCTGGAAGATTGAGGTTCCTGGACAGATCAGGCTAGCCCTGCC
CTCCACCCACACCTGCCCGCTCCCCACGATAAGCACCAGTGGGACTGTGGTGACTTCTGCTGCTGGCCCCGCCCCTGCCCCCAGAGCGTC
CTTGGCTGCCGTCTGGCCGGGCTCTCATGGTACTTCCTCTGTGAACTGTGTGTGAATCTGCTTTTCCTCTGCCTTCGGAGGGAAATTGTA

>In-frame_ENST00000420323_ENST00000330452_TCGA-24-1603-01A_DNAH1_chr3_52391751_+_PRKCD_chr3_53221356_length(amino acids)=1577AA_start in transcript=186_stop in transcript=4919
MDSGKVAPPSGLEGSFGWGISLRSSMEQPNSKGYSLGRTPQGPECSSAPAVQVGTHRGLEYNPGKILPGSDYGLGNPPALDPKLPHLPLP
PAPPTLSDLGQPRKSPLTGTDKKYPLMKQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQCIG
STTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQLLFSQGIDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPL
KVFDNEDFDCRTPREWINMGLEPGSLDRKPVPGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRP
ILNAGVTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEALLLYNLYVDCMPSDGQHVISEQSLSKIKQWALSTPRMR
KGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSK
VRAECNKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMELVKY
MLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATH
AVPQLEKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLT
HLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIP
ERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSI
HVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEK
NVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESI
SKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLE
EWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAF
PRFYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLY
EMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLGVTGNIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRD

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Fusion Gene PPI Analysis for DNAH1-PRKCD


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DNAH1-PRKCD


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DNAH1-PRKCD


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneDNAH1C4539783SPERMATOGENIC FAILURE 184GENOMICS_ENGLAND;UNIPROT
HgeneDNAH1C4539798CILIARY DYSKINESIA, PRIMARY, 372GENOMICS_ENGLAND;UNIPROT
HgeneDNAH1C0022521Kartagener Syndrome1ORPHANET
HgeneDNAH1C4317124Polynesian Bronchiectasis1ORPHANET
HgeneDNAH1C4551720Primary Ciliary Dyskinesia1ORPHANET
HgeneDNAH1C4551906Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus1ORPHANET
TgenePRKCDC0002152Alloxan Diabetes1CTD_human
TgenePRKCDC0009447Common Variable Immunodeficiency1ORPHANET
TgenePRKCDC0011853Diabetes Mellitus, Experimental1CTD_human
TgenePRKCDC0019193Hepatitis, Toxic1CTD_human
TgenePRKCDC0020538Hypertensive disease1CTD_human
TgenePRKCDC0020672Hypothermia, natural1CTD_human
TgenePRKCDC0021841Intestinal Neoplasms1CTD_human
TgenePRKCDC0022333Jacksonian Seizure1CTD_human
TgenePRKCDC0023893Liver Cirrhosis, Experimental1CTD_human
TgenePRKCDC0036572Seizures1CTD_human
TgenePRKCDC0038433Streptozotocin Diabetes1CTD_human
TgenePRKCDC0149504Encephalopathy, Toxic1CTD_human
TgenePRKCDC0149958Complex partial seizures1CTD_human
TgenePRKCDC0154659Toxic Encephalitis1CTD_human
TgenePRKCDC0234533Generalized seizures1CTD_human
TgenePRKCDC0234535Clonic Seizures1CTD_human
TgenePRKCDC0235032Neurotoxicity Syndromes1CTD_human
TgenePRKCDC0242422Parkinsonian Disorders1CTD_human
TgenePRKCDC0242423Ramsay Hunt Paralysis Syndrome1CTD_human
TgenePRKCDC0270824Visual seizure1CTD_human
TgenePRKCDC0270844Tonic Seizures1CTD_human
TgenePRKCDC0270846Epileptic drop attack1CTD_human
TgenePRKCDC0346627Intestinal Cancer1CTD_human
TgenePRKCDC0400966Non-alcoholic Fatty Liver Disease1CTD_human
TgenePRKCDC0422850Seizures, Somatosensory1CTD_human
TgenePRKCDC0422852Seizures, Auditory1CTD_human
TgenePRKCDC0422853Olfactory seizure1CTD_human
TgenePRKCDC0422854Gustatory seizure1CTD_human
TgenePRKCDC0422855Vertiginous seizure1CTD_human
TgenePRKCDC0494475Tonic - clonic seizures1CTD_human
TgenePRKCDC0751056Non-epileptic convulsion1CTD_human
TgenePRKCDC0751110Single Seizure1CTD_human
TgenePRKCDC0751123Atonic Absence Seizures1CTD_human
TgenePRKCDC0751494Convulsive Seizures1CTD_human
TgenePRKCDC0751495Seizures, Focal1CTD_human
TgenePRKCDC0751496Seizures, Sensory1CTD_human
TgenePRKCDC0752097Autosomal Dominant Juvenile Parkinson Disease1CTD_human
TgenePRKCDC0752098Autosomal Dominant Parkinsonism1CTD_human
TgenePRKCDC0752100Autosomal Recessive Parkinsonism1CTD_human
TgenePRKCDC0752101Parkinsonism, Experimental1CTD_human
TgenePRKCDC0752104Familial Juvenile Parkinsonism1CTD_human
TgenePRKCDC0752105Parkinsonism, Juvenile1CTD_human
TgenePRKCDC0860207Drug-Induced Liver Disease1CTD_human
TgenePRKCDC1262760Hepatitis, Drug-Induced1CTD_human
TgenePRKCDC1328840Autoimmune Lymphoproliferative Syndrome1ORPHANET
TgenePRKCDC1868675PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE1CTD_human
TgenePRKCDC3241937Nonalcoholic Steatohepatitis1CTD_human
TgenePRKCDC3280742SYSTEMIC LUPUS ERYTHEMATOSUS 161ORPHANET
TgenePRKCDC3495874Nonepileptic Seizures1CTD_human
TgenePRKCDC3658290Drug-Induced Acute Liver Injury1CTD_human
TgenePRKCDC3809928AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE III1CTD_human;GENOMICS_ENGLAND
TgenePRKCDC4048158Convulsions1CTD_human
TgenePRKCDC4277682Chemical and Drug Induced Liver Injury1CTD_human
TgenePRKCDC4279912Chemically-Induced Liver Toxicity1CTD_human
TgenePRKCDC4316903Absence Seizures1CTD_human
TgenePRKCDC4317109Epileptic Seizures1CTD_human
TgenePRKCDC4317123Myoclonic Seizures1CTD_human
TgenePRKCDC4505436Generalized Absence Seizures1CTD_human