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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AASDH-LRRC66 (FusionGDB2 ID:241)

Fusion Gene Summary for AASDH-LRRC66

check button Fusion gene summary
Fusion gene informationFusion gene name: AASDH-LRRC66
Fusion gene ID: 241
HgeneTgene
Gene symbol

AASDH

LRRC66

Gene ID

132949

339977

Gene nameaminoadipate-semialdehyde dehydrogenaseleucine rich repeat containing 66
SynonymsACSF4|LYS2|NRPS1098|NRPS998-
Cytomap

4q12

4q12

Type of geneprotein-codingprotein-coding
Descriptionbeta-alanine-activating enzyme2-aminoadipic 6-semialdehyde dehydrogenaseacyl-CoA synthetase family member 4non-ribosomal peptide synthetase 1098non-ribosomal peptide synthetase 998leucine-rich repeat-containing protein 66
Modification date2020031320200313
UniProtAcc

Q4L235

.
Ensembl transtripts involved in fusion geneENST00000513376, ENST00000205214, 
ENST00000434343, ENST00000451613, 
ENST00000602986, ENST00000502617, 
ENST00000510762, 		ENST00000343457, 
Fusion gene scores* DoF score6 X 7 X 4=1682 X 2 X 2=8
# samples 73
** MAII scorelog2(7/168*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/8*10)=1.90689059560852
Context

PubMed: AASDH [Title/Abstract] AND LRRC66 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAASDH(57217508)-LRRC66(52869558), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across AASDH (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across LRRC66 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-2559-01AAASDHchr4

57217508

-LRRC66chr4

52869558

-
ChimerDB4GBMTCGA-06-2559AASDHchr4

57217507

-LRRC66chr4

52864103

-
ChimerDB4GBMTCGA-06-2559-01AAASDHchr4

57217508

-LRRC66chr4

52869558

-
ChimerDB4GBMTCGA-06-2559-01AAASDHchr4

57217508

-LRRC66chr4

52864103

-
ChimerDB4GBMTCGA-06-2559-01AAASDHchr4

57217508

-LRRC66chr4

52869558

-


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Fusion Gene ORF analysis for AASDH-LRRC66

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000513376ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52869558

-
In-frameENST00000205214ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52869558

-
Frame-shiftENST00000434343ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52869558

-
In-frameENST00000451613ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52869558

-
Frame-shiftENST00000602986ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52869558

-
In-frameENST00000502617ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52869558

-
intron-3CDSENST00000510762ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52869558

-
In-frameENST00000513376ENST00000343457AASDHchr4

57217507

-LRRC66chr4

52864103

-
Frame-shiftENST00000205214ENST00000343457AASDHchr4

57217507

-LRRC66chr4

52864103

-
In-frameENST00000434343ENST00000343457AASDHchr4

57217507

-LRRC66chr4

52864103

-
Frame-shiftENST00000451613ENST00000343457AASDHchr4

57217507

-LRRC66chr4

52864103

-
In-frameENST00000602986ENST00000343457AASDHchr4

57217507

-LRRC66chr4

52864103

-
Frame-shiftENST00000502617ENST00000343457AASDHchr4

57217507

-LRRC66chr4

52864103

-
intron-3CDSENST00000510762ENST00000343457AASDHchr4

57217507

-LRRC66chr4

52864103

-
In-frameENST00000513376ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52864103

-
Frame-shiftENST00000205214ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52864103

-
In-frameENST00000434343ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52864103

-
Frame-shiftENST00000451613ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52864103

-
In-frameENST00000602986ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52864103

-
Frame-shiftENST00000502617ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52864103

-
intron-3CDSENST00000510762ENST00000343457AASDHchr4

57217508

-LRRC66chr4

52864103

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000205214AASDHchr457217508-ENST00000343457LRRC66chr452869558-4697187318454019724
ENST00000451613AASDHchr457217508-ENST00000343457LRRC66chr452869558-4686186218344008724
ENST00000502617AASDHchr457217508-ENST00000343457LRRC66chr452869558-4697187318454019724
ENST00000513376AASDHchr457217507-ENST00000343457LRRC66chr452864103-4178152413235001122
ENST00000434343AASDHchr457217507-ENST00000343457LRRC66chr452864103-3899124510083221737
ENST00000602986AASDHchr457217507-ENST00000343457LRRC66chr452864103-4367171333336891118
ENST00000513376AASDHchr457217508-ENST00000343457LRRC66chr452864103-4178152413235001122
ENST00000434343AASDHchr457217508-ENST00000343457LRRC66chr452864103-3899124510083221737
ENST00000602986AASDHchr457217508-ENST00000343457LRRC66chr452864103-4367171333336891118

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000205214ENST00000343457AASDHchr457217508-LRRC66chr452869558-0.000841690.99915826
ENST00000451613ENST00000343457AASDHchr457217508-LRRC66chr452869558-0.0008535660.99914646
ENST00000502617ENST00000343457AASDHchr457217508-LRRC66chr452869558-0.000841690.99915826
ENST00000513376ENST00000343457AASDHchr457217507-LRRC66chr452864103-0.0002747970.99972516
ENST00000434343ENST00000343457AASDHchr457217507-LRRC66chr452864103-0.0015067550.9984932
ENST00000602986ENST00000343457AASDHchr457217507-LRRC66chr452864103-0.0004034710.99959654
ENST00000513376ENST00000343457AASDHchr457217508-LRRC66chr452864103-0.0002747970.99972516
ENST00000434343ENST00000343457AASDHchr457217508-LRRC66chr452864103-0.0015067550.9984932
ENST00000602986ENST00000343457AASDHchr457217508-LRRC66chr452864103-0.0004034710.99959654

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Fusion Genomic Features for AASDH-LRRC66


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for AASDH-LRRC66


check button Go to

FGviewer for the breakpoints of chr4:57217508-chr4:52869558

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AASDH

Q4L235

.
FUNCTION: Covalently binds beta-alanine in an ATP-dependent manner to form a thioester bond with its phosphopantetheine group and transfers it to an, as yet, unknown acceptor. May be required for a post-translational protein modification or for post-transcriptional modification of an RNA. {ECO:0000250|UniProtKB:Q80WC9}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAASDHchr4:57217507chr4:52864103ENST00000205214-1015198_206564.01099.0Nucleotide bindingATP
HgeneAASDHchr4:57217507chr4:52864103ENST00000451613-1012198_206564.0858.0Nucleotide bindingATP
HgeneAASDHchr4:57217507chr4:52864103ENST00000502617-1011198_206564.0842.0Nucleotide bindingATP
HgeneAASDHchr4:57217507chr4:52864103ENST00000513376-914198_206464.0999.0Nucleotide bindingATP
HgeneAASDHchr4:57217508chr4:52864103ENST00000205214-1015198_206564.01099.0Nucleotide bindingATP
HgeneAASDHchr4:57217508chr4:52864103ENST00000451613-1012198_206564.0858.0Nucleotide bindingATP
HgeneAASDHchr4:57217508chr4:52864103ENST00000502617-1011198_206564.0842.0Nucleotide bindingATP
HgeneAASDHchr4:57217508chr4:52864103ENST00000513376-914198_206464.0999.0Nucleotide bindingATP
HgeneAASDHchr4:57217508chr4:52869558ENST00000205214-1015198_206564.01099.0Nucleotide bindingATP
HgeneAASDHchr4:57217508chr4:52869558ENST00000451613-1012198_206564.0858.0Nucleotide bindingATP
HgeneAASDHchr4:57217508chr4:52869558ENST00000502617-1011198_206564.0842.0Nucleotide bindingATP
HgeneAASDHchr4:57217508chr4:52869558ENST00000513376-914198_206464.0999.0Nucleotide bindingATP
TgeneLRRC66chr4:57217507chr4:52864103ENST0000034345714220_241222.0881.0RepeatNote=LRR 6
TgeneLRRC66chr4:57217508chr4:52864103ENST0000034345714220_241222.0881.0RepeatNote=LRR 6
TgeneLRRC66chr4:57217508chr4:52869558ENST0000034345704172_193165.33333333333334881.0RepeatNote=LRR 4
TgeneLRRC66chr4:57217508chr4:52869558ENST0000034345704196_217165.33333333333334881.0RepeatNote=LRR 5
TgeneLRRC66chr4:57217508chr4:52869558ENST0000034345704220_241165.33333333333334881.0RepeatNote=LRR 6
TgeneLRRC66chr4:57217507chr4:52864103ENST0000034345714376_396222.0881.0TransmembraneHelical
TgeneLRRC66chr4:57217508chr4:52864103ENST0000034345714376_396222.0881.0TransmembraneHelical
TgeneLRRC66chr4:57217508chr4:52869558ENST0000034345704376_396165.33333333333334881.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAASDHchr4:57217507chr4:52864103ENST00000205214-1015553_630564.01099.0DomainCarrier
HgeneAASDHchr4:57217507chr4:52864103ENST00000451613-1012553_630564.0858.0DomainCarrier
HgeneAASDHchr4:57217507chr4:52864103ENST00000502617-1011553_630564.0842.0DomainCarrier
HgeneAASDHchr4:57217507chr4:52864103ENST00000513376-914553_630464.0999.0DomainCarrier
HgeneAASDHchr4:57217508chr4:52864103ENST00000205214-1015553_630564.01099.0DomainCarrier
HgeneAASDHchr4:57217508chr4:52864103ENST00000451613-1012553_630564.0858.0DomainCarrier
HgeneAASDHchr4:57217508chr4:52864103ENST00000502617-1011553_630564.0842.0DomainCarrier
HgeneAASDHchr4:57217508chr4:52864103ENST00000513376-914553_630464.0999.0DomainCarrier
HgeneAASDHchr4:57217508chr4:52869558ENST00000205214-1015553_630564.01099.0DomainCarrier
HgeneAASDHchr4:57217508chr4:52869558ENST00000451613-1012553_630564.0858.0DomainCarrier
HgeneAASDHchr4:57217508chr4:52869558ENST00000502617-1011553_630564.0842.0DomainCarrier
HgeneAASDHchr4:57217508chr4:52869558ENST00000513376-914553_630464.0999.0DomainCarrier
TgeneLRRC66chr4:57217507chr4:52864103ENST0000034345714110_130222.0881.0RepeatNote=LRR 2
TgeneLRRC66chr4:57217507chr4:52864103ENST0000034345714149_171222.0881.0RepeatNote=LRR 3
TgeneLRRC66chr4:57217507chr4:52864103ENST0000034345714172_193222.0881.0RepeatNote=LRR 4
TgeneLRRC66chr4:57217507chr4:52864103ENST0000034345714196_217222.0881.0RepeatNote=LRR 5
TgeneLRRC66chr4:57217507chr4:52864103ENST000003434571486_107222.0881.0RepeatNote=LRR 1
TgeneLRRC66chr4:57217508chr4:52864103ENST0000034345714110_130222.0881.0RepeatNote=LRR 2
TgeneLRRC66chr4:57217508chr4:52864103ENST0000034345714149_171222.0881.0RepeatNote=LRR 3
TgeneLRRC66chr4:57217508chr4:52864103ENST0000034345714172_193222.0881.0RepeatNote=LRR 4
TgeneLRRC66chr4:57217508chr4:52864103ENST0000034345714196_217222.0881.0RepeatNote=LRR 5
TgeneLRRC66chr4:57217508chr4:52864103ENST000003434571486_107222.0881.0RepeatNote=LRR 1
TgeneLRRC66chr4:57217508chr4:52869558ENST0000034345704110_130165.33333333333334881.0RepeatNote=LRR 2
TgeneLRRC66chr4:57217508chr4:52869558ENST0000034345704149_171165.33333333333334881.0RepeatNote=LRR 3
TgeneLRRC66chr4:57217508chr4:52869558ENST000003434570486_107165.33333333333334881.0RepeatNote=LRR 1
TgeneLRRC66chr4:57217507chr4:52864103ENST00000343457144_24222.0881.0TransmembraneHelical
TgeneLRRC66chr4:57217508chr4:52864103ENST00000343457144_24222.0881.0TransmembraneHelical
TgeneLRRC66chr4:57217508chr4:52869558ENST00000343457044_24165.33333333333334881.0TransmembraneHelical


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Fusion Gene Sequence for AASDH-LRRC66


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000205214_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52869558_length(transcript)=4697nt_BP=1873nt
GGAAGATTTACGTATGGTGCCTCGCTCTGGGATAGCTTTACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTA
TCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGA
AATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTGTTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCC
AGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTCTGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGA
AATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTCTTGGATTTTAGGAATTCTCCAAGTCCCGGCTGCTTATGTACCTATCGAGCC
AGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATAAATTTAA
ATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGGAAAAATACTGA
GGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGC
AGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGT
GCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCTGGCTTCACCTCT
GACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGTCAAGTTGCTCCC
ATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATTTGGATCTCAGCT
TATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGACAGTTCTCAGAAG
CTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTATAGGATTCCAGA
GAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTAGTTGAAGTCAGAGATACTAA
TGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGATGATGAAGTGACAGTACCACT
TGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAAGACAGTCAGATCAAACGTCA
TGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGGTATAATCAGGA
AAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCAAGTCATGCAGT
CCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATATATTTAAACTA
CATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGACTGTGGAAACTGAAG
TCATTGCAGAGTTTGGATCTGTCATTCAATGGGATATTGCAAATAGGGTGGTCTGATTTTCACAACTGCCTGCAACTGGAGAATCTCTGT
TTAAAGAGCAACAAGATATTCAAAATTCCCCCACAAGCCTTCAAGGACCTCAAAAAATTACAGGTCATAGACCTTAGCAACAATGCTCTG
ATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAATAACTGGCAGTGTGATGATAGT
GTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCTATAGGGAGTGAGGAGGCCAAC
GGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAAAGCCTCATAAGGAGCAAAGCA
GAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGTCTCAGGAAGAAGCAGAGACGG
CTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGACCTGGCTCTGGCGGTGTGCCTG
TCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTGTGGCAAAAAAAGTGCCAGAGC
AAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCACACACCACACCCAGAGACCCAT
CTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACACCCACACGCCACCGTAATTCCT
GATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAACACCGGGGCAGGAAGTGGAAAT
GATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCGCAGGACCACATCCATAGGAAT
GATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGCGTCTCTTCTGTAGCTGGCACG
TCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATAACAGCTTCCCTCTGTAAAATG
CTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGGGACTCGCAGATGGAATTTTCT
AAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGGGCTGAGGAAGCGCTTTCAGCC
CACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGACAGTGGCCTGGATGTCACTCCT
GCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGACTCTGATGAGGGGTCTCTGTTC
ACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCCCTGCAGGACGAGAGCTCAGGG
GCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGGAAATGCAAGAATCAAGAAGAT
CCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCTGACACTGATAGATCTGAGGGC
CTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTATGATTATGACACAGCTCTTCAA
TCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAAACACCACCATGTTCTGCTGAA
GTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTCATTAAGGAAATATTCACAGCT
CTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAGACAACATGAATTCCAACCAAG
TGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCTAAACACACTTGTTAACATCCT
ATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCATGCACCATTATTACAAGAGCT
CCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGAGAATCTGTTGCAGTTAGACGA
AGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGAACAGCTTTAGGATGACAAAGA
CAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAAGTGGAAATGCTGGATAGATTT
TAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAGTTCTGAGTAAATATAAATGTT

>In-frame_ENST00000205214_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52869558_length(amino acids)=724AA_start in transcript=1845_stop in transcript=4019
MGKITVFVEGLWKLKSLQSLDLSFNGILQIGWSDFHNCLQLENLCLKSNKIFKIPPQAFKDLKKLQVIDLSNNALITILPMMIIALEFPH
LVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLG
KKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFY
DDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAG
NRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKER
GGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTC
CELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMY
KTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVPSDPDKAAFHERDS

--------------------------------------------------------------
>In-frame_ENST00000451613_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52869558_length(transcript)=4686nt_BP=1862nt
GTATGGTGCCTCGCTCTGGGATAGCTTTACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGG
GCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTC
AGGAATTGGTGCATAAGGCTGCCTCCTGTTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACA
CCTACAAGACTGTGGTTAATGCTGCTTCTGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCT
ACTGCCAACCTGGGATAGACTTACCCTCTTGGATTTTAGGAATTCTCCAAGTCCCGGCTGCTTATGTACCTATCGAGCCAGATTCACCAC
CGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATAAATTTAAATCTTTTCATG
AAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGGAAAAATACTGAGGTGAACTTGA
TGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGCAGAAGAACACA
TGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGTGCCTCATAAGT
GTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCTGGCTTCACCTCTGACCTTCGATC
CTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGTCAAGTTGCTCCCATCAAAATTAG
CCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATTTGGATCTCAGCTTATCAAGTCAA
CTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGACAGTTCTCAGAAGCTGGAGAGGAG
AAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTATAGGATTCCAGAGAAGACTCTTA
ACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTAGTTGAAGTCAGAGATACTAATGGCTTCACAA
TTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGATGATGAAGTGACAGTACCACTTGGCACAATGC
GAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAAGACAGTCAGATCAAACGTCATGGCAAACGTC
TTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGGTATAATCAGGAAAAATTAATTC
TCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCAAGTCATGCAGTCCCGGATGAGC
TTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATATATTTAAACTACATAAACTTGA
AGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGACTGTGGAAACTGAAGTCATTGCAGAG
TTTGGATCTGTCATTCAATGGGATATTGCAAATAGGGTGGTCTGATTTTCACAACTGCCTGCAACTGGAGAATCTCTGTTTAAAGAGCAA
CAAGATATTCAAAATTCCCCCACAAGCCTTCAAGGACCTCAAAAAATTACAGGTCATAGACCTTAGCAACAATGCTCTGATTACCATCCT
ACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAATAACTGGCAGTGTGATGATAGTGTGGCAGTCTT
TCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCTATAGGGAGTGAGGAGGCCAACGGGGGCACTCC
CCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAAAGCCTCATAAGGAGCAAAGCAGAGAGGCCCCA
GGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGTCTCAGGAAGAAGCAGAGACGGCTGCCAAGGAG
TGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGACCTGGCTCTGGCGGTGTGCCTGTCAGTGTTCAT
CACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTGTGGCAAAAAAAGTGCCAGAGCAAAAGCCCTGG
CCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCACACACCACACCCAGAGACCCATCTGCGCCAAGT
ATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACACCCACACGCCACCGTAATTCCTGATAGAACTCT
GGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAACACCGGGGCAGGAAGTGGAAATGATGGTGCAGT
CTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCGCAGGACCACATCCATAGGAATGATATTCTCGG
AGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGCGTCTCTTCTGTAGCTGGCACGTCTCACGCTGT
CTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATAACAGCTTCCCTCTGTAAAATGCTAACACATGC
AGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGGGACTCGCAGATGGAATTTTCTAAGGAAAGGCA
AGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGGGCTGAGGAAGCGCTTTCAGCCCACTACAGCGA
GGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGACAGTGGCCTGGATGTCACTCCTGCTAACAAGGA
ACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGACTCTGATGAGGGGTCTCTGTTCACTCTGAGCTC
CATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCCCTGCAGGACGAGAGCTCAGGGGCAAGCAAGGA
CAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGGAAATGCAAGAATCAAGAAGATCCCTTTGAAAA
ACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCTGACACTGATAGATCTGAGGGCCTGTCACCCTG
GCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTATGATTATGACACAGCTCTTCAATCCAAGGCAGC
AGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAAACACCACCATGTTCTGCTGAAGTTCCCTCAGA
TCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTCATTAAGGAAATATTCACAGCTCTAAACAATAT
TCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAGACAACATGAATTCCAACCAAGTGGACACTGAT
GCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCTAAACACACTTGTTAACATCCTATGGGGATGAA
CCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCATGCACCATTATTACAAGAGCTCCAAACAAAAC
CAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGAGAATCTGTTGCAGTTAGACGAAGTGGTTCTAA
CTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGAACAGCTTTAGGATGACAAAGACAAGGATGTTC
AACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAAGTGGAAATGCTGGATAGATTTTAATGAATTCT
GAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAGTTCTGAGTAAATATAAATGTTTTTAAATAAGT

>In-frame_ENST00000451613_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52869558_length(amino acids)=724AA_start in transcript=1834_stop in transcript=4008
MGKITVFVEGLWKLKSLQSLDLSFNGILQIGWSDFHNCLQLENLCLKSNKIFKIPPQAFKDLKKLQVIDLSNNALITILPMMIIALEFPH
LVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLG
KKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFY
DDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAG
NRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKER
GGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTC
CELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMY
KTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVPSDPDKAAFHERDS

--------------------------------------------------------------
>In-frame_ENST00000502617_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52869558_length(transcript)=4697nt_BP=1873nt
GGAAGATTTACGTATGGTGCCTCGCTCTGGGATAGCTTTACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTA
TCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGA
AATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTGTTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCC
AGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTCTGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGA
AATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTCTTGGATTTTAGGAATTCTCCAAGTCCCGGCTGCTTATGTACCTATCGAGCC
AGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATAAATTTAA
ATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGGAAAAATACTGA
GGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGC
AGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGT
GCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCTGGCTTCACCTCT
GACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGTCAAGTTGCTCCC
ATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATTTGGATCTCAGCT
TATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGACAGTTCTCAGAAG
CTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTATAGGATTCCAGA
GAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTAGTTGAAGTCAGAGATACTAA
TGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGATGATGAAGTGACAGTACCACT
TGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAAGACAGTCAGATCAAACGTCA
TGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGGTATAATCAGGA
AAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCAAGTCATGCAGT
CCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATATATTTAAACTA
CATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGACTGTGGAAACTGAAG
TCATTGCAGAGTTTGGATCTGTCATTCAATGGGATATTGCAAATAGGGTGGTCTGATTTTCACAACTGCCTGCAACTGGAGAATCTCTGT
TTAAAGAGCAACAAGATATTCAAAATTCCCCCACAAGCCTTCAAGGACCTCAAAAAATTACAGGTCATAGACCTTAGCAACAATGCTCTG
ATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAATAACTGGCAGTGTGATGATAGT
GTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCTATAGGGAGTGAGGAGGCCAAC
GGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAAAGCCTCATAAGGAGCAAAGCA
GAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGTCTCAGGAAGAAGCAGAGACGG
CTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGACCTGGCTCTGGCGGTGTGCCTG
TCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTGTGGCAAAAAAAGTGCCAGAGC
AAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCACACACCACACCCAGAGACCCAT
CTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACACCCACACGCCACCGTAATTCCT
GATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAACACCGGGGCAGGAAGTGGAAAT
GATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCGCAGGACCACATCCATAGGAAT
GATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGCGTCTCTTCTGTAGCTGGCACG
TCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATAACAGCTTCCCTCTGTAAAATG
CTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGGGACTCGCAGATGGAATTTTCT
AAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGGGCTGAGGAAGCGCTTTCAGCC
CACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGACAGTGGCCTGGATGTCACTCCT
GCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGACTCTGATGAGGGGTCTCTGTTC
ACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCCCTGCAGGACGAGAGCTCAGGG
GCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGGAAATGCAAGAATCAAGAAGAT
CCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCTGACACTGATAGATCTGAGGGC
CTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTATGATTATGACACAGCTCTTCAA
TCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAAACACCACCATGTTCTGCTGAA
GTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTCATTAAGGAAATATTCACAGCT
CTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAGACAACATGAATTCCAACCAAG
TGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCTAAACACACTTGTTAACATCCT
ATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCATGCACCATTATTACAAGAGCT
CCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGAGAATCTGTTGCAGTTAGACGA
AGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGAACAGCTTTAGGATGACAAAGA
CAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAAGTGGAAATGCTGGATAGATTT
TAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAGTTCTGAGTAAATATAAATGTT

>In-frame_ENST00000502617_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52869558_length(amino acids)=724AA_start in transcript=1845_stop in transcript=4019
MGKITVFVEGLWKLKSLQSLDLSFNGILQIGWSDFHNCLQLENLCLKSNKIFKIPPQAFKDLKKLQVIDLSNNALITILPMMIIALEFPH
LVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLG
KKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFY
DDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAG
NRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKER
GGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTC
CELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMY
KTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVPSDPDKAAFHERDS

--------------------------------------------------------------
>In-frame_ENST00000513376_ENST00000343457_TCGA-06-2559_AASDH_chr4_57217507_-_LRRC66_chr4_52864103_length(transcript)=4178nt_BP=1524nt
CCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAAATTCTCCAAGTCCCGGCTGCTTATGTA
CCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATT
AATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGG
AAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAAT
GAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAG
ATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCTG
GCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGTC
AAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATTT
GGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGACA
GTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTAT
AGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTAGTTGAAGTC
AGAGATACTAATGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGATGATGAAGTG
ACAGTACCACTTGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAAGACAGTCAG
ATCAAACGTCATGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGG
TATAATCAGGAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCA
AGTCATGCAGTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATA
TATTTAAACTACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGTCATA
GACCTTAGCAACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAAT
AACTGGCAGTGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCT
ATAGGGAGTGAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAA
AGCCTCATAAGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGT
CTCAGGAAGAAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGAC
CTGGCTCTGGCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTG
TGGCAAAAAAAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCAC
ACACCACACCCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACAC
CCACACGCCACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAAC
ACCGGGGCAGGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCG
CAGGACCACATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGC
GTCTCTTCTGTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATA
ACAGCTTCCCTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGG
GACTCGCAGATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGG
GCTGAGGAAGCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGAC
AGTGGCCTGGATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGAC
TCTGATGAGGGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCC
CTGCAGGACGAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGG
AAATGCAAGAATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCT
GACACTGATAGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTAT
GATTATGACACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAA
ACACCACCATGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTC
ATTAAGGAAATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAG
ACAACATGAATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCT
AAACACACTTGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCA
TGCACCATTATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGA
GAATCTGTTGCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGA
ACAGCTTTAGGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAA
GTGGAAATGCTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAG

>In-frame_ENST00000513376_ENST00000343457_TCGA-06-2559_AASDH_chr4_57217507_-_LRRC66_chr4_52864103_length(amino acids)=1122AA_start in transcript=132_stop in transcript=3500
MKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKH
CLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSH
HRVTVLQATPTLLRRFGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCE
LPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQ
QVAEELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLS
GKEDLWEKLQYLWKVIDLSNNALITILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSR
ISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFL
VAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRS
RKDPGSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGS
SRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPY
GDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVT
AVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWH

--------------------------------------------------------------
>In-frame_ENST00000434343_ENST00000343457_TCGA-06-2559_AASDH_chr4_57217507_-_LRRC66_chr4_52864103_length(transcript)=3899nt_BP=1245nt
ATAGCTTTACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTA
ATCCGCGAGACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCT
GCCTCCTGTTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAAT
GCTGCTTCTGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGAC
TTACCCTCTTGGATTTTAGGAATTCTCCAAGTCCCGGCTGCTTATGTACCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTT
ATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCT
GGCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGT
CAAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATT
TGGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGAC
AGTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTA
TAGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGGTATAATCAG
GAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCAAGTCATGCA
GTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATATATTTAAAC
TACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGTCATAGACCTTAGC
AACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAATAACTGGCAG
TGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCTATAGGGAGT
GAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAAAGCCTCATA
AGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGTCTCAGGAAG
AAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGACCTGGCTCTG
GCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTGTGGCAAAAA
AAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCACACACCACAC
CCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACACCCACACGCC
ACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAACACCGGGGCA
GGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCGCAGGACCAC
ATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGCGTCTCTTCT
GTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATAACAGCTTCC
CTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGGGACTCGCAG
ATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGGGCTGAGGAA
GCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGACAGTGGCCTG
GATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGACTCTGATGAG
GGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCCCTGCAGGAC
GAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGGAAATGCAAG
AATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCTGACACTGAT
AGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTATGATTATGAC
ACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAAACACCACCA
TGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTCATTAAGGAA
ATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAGACAACATGA
ATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCTAAACACACT
TGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCATGCACCATT
ATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGAGAATCTGTT
GCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGAACAGCTTTA
GGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAAGTGGAAATG
CTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAGTTCTGAGTA

>In-frame_ENST00000434343_ENST00000343457_TCGA-06-2559_AASDH_chr4_57217507_-_LRRC66_chr4_52864103_length(amino acids)=737AA_start in transcript=1008_stop in transcript=3221
MVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLSGKEDLWEKLQYLWKVIDLSNNALIT
ILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAER
PQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKS
PGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSGNDG
AVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLT
HAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPAN
KEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPF
EKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVP

--------------------------------------------------------------
>In-frame_ENST00000602986_ENST00000343457_TCGA-06-2559_AASDH_chr4_57217507_-_LRRC66_chr4_52864103_length(transcript)=4367nt_BP=1713nt
ACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGA
GACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTG
TTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTC
TGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTC
TTGGATTTTAGGAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGA
CTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAG
CATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGG
ATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTT
TTGTTTCTGGCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCA
ACTTCCGTCAAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTT
AGAAGATTTGGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCA
TCATTGACAGTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCG
ACCATTTATAGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTA
GTTGAAGTCAGAGATACTAATGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGAT
GATGAAGTGACAGTACCACTTGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAA
GACAGTCAGATCAAACGTCATGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCA
GTTACATGGTATAATCAGGAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAA
TATCTTCCAAGTCATGCAGTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTA
AACAAGATATATTTAAACTACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGG
AAGGTCATAGACCTTAGCAACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTG
GCTGATAATAACTGGCAGTGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGC
AACAGGTCTATAGGGAGTGAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCAT
CGCATGAAAAGCCTCATAAGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCC
GGCTCTGGTCTCAGGAAGAAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCT
CCCCAGGACCTGGCTCTGGCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTT
GACAGACTGTGGCAAAAAAAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCT
GCGGGGCACACACCACACCCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACA
CAGCCACACCCACACGCCACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGC
GGGGACAACACCGGGGCAGGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATG
TCAGCAGCGCAGGACCACATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACAT
TCAGTGGGCGTCTCTTCTGTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCC
GGAGAAATAACAGCTTCCCTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAG
TCACTTTGGGACTCGCAGATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCC
GGGGCAAGGGCTGAGGAAGCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCA
AGATGGGACAGTGGCCTGGATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGT
GACTGTGACTCTGATGAGGGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGAT
GAGGAGTCCCTGCAGGACGAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACA
ATTCCAGGGAAATGCAAGAATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAA
AATGCCTCTGACACTGATAGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATG
TTCACTTATGATTATGACACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTT
TTACAGCAAACACCACCATGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAA
GAATCTTTCATTAAGGAAATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATC
CTGAAGGAGACAACATGAATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGG
TTATAAGCTAAACACACTTGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTC
CAAGAACCATGCACCATTATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATA
TTCAGAAGAGAATCTGTTGCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCT
CTGAAAAGAACAGCTTTAGGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGA
AGCACTTAAGTGGAAATGCTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAA

>In-frame_ENST00000602986_ENST00000343457_TCGA-06-2559_AASDH_chr4_57217507_-_LRRC66_chr4_52864103_length(amino acids)=1118AA_start in transcript=333_stop in transcript=3689
MPTWDRLTLLDFRKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHCLAY
VLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVT
VLQATPTLLRRFGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCELPVQ
LGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAE
ELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLSGKED
LWEKLQYLWKVIDLSNNALITILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRE
TRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFS
LGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDP
GSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYD
SNELDPSLSGEITASLCKMLTHAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPR
DTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDS
LEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLR

--------------------------------------------------------------
>In-frame_ENST00000513376_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52864103_length(transcript)=4178nt_BP=1524nt
CCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAAATTCTCCAAGTCCCGGCTGCTTATGTA
CCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATT
AATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGG
AAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAAT
GAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAG
ATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCTG
GCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGTC
AAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATTT
GGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGACA
GTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTAT
AGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTAGTTGAAGTC
AGAGATACTAATGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGATGATGAAGTG
ACAGTACCACTTGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAAGACAGTCAG
ATCAAACGTCATGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGG
TATAATCAGGAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCA
AGTCATGCAGTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATA
TATTTAAACTACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGTCATA
GACCTTAGCAACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAAT
AACTGGCAGTGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCT
ATAGGGAGTGAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAA
AGCCTCATAAGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGT
CTCAGGAAGAAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGAC
CTGGCTCTGGCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTG
TGGCAAAAAAAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCAC
ACACCACACCCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACAC
CCACACGCCACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAAC
ACCGGGGCAGGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCG
CAGGACCACATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGC
GTCTCTTCTGTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATA
ACAGCTTCCCTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGG
GACTCGCAGATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGG
GCTGAGGAAGCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGAC
AGTGGCCTGGATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGAC
TCTGATGAGGGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCC
CTGCAGGACGAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGG
AAATGCAAGAATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCT
GACACTGATAGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTAT
GATTATGACACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAA
ACACCACCATGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTC
ATTAAGGAAATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAG
ACAACATGAATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCT
AAACACACTTGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCA
TGCACCATTATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGA
GAATCTGTTGCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGA
ACAGCTTTAGGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAA
GTGGAAATGCTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAG

>In-frame_ENST00000513376_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52864103_length(amino acids)=1122AA_start in transcript=132_stop in transcript=3500
MKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKH
CLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSH
HRVTVLQATPTLLRRFGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCE
LPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQ
QVAEELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLS
GKEDLWEKLQYLWKVIDLSNNALITILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSR
ISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFL
VAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRS
RKDPGSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGS
SRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPY
GDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVT
AVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWH

--------------------------------------------------------------
>In-frame_ENST00000434343_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52864103_length(transcript)=3899nt_BP=1245nt
ATAGCTTTACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTA
ATCCGCGAGACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCT
GCCTCCTGTTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAAT
GCTGCTTCTGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGAC
TTACCCTCTTGGATTTTAGGAATTCTCCAAGTCCCGGCTGCTTATGTACCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTT
ATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATGGTACTTTTTGACATCACACAAGAAGATGTTTTGTTTCT
GGCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCAACTTCCGT
CAAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTTAGAAGATT
TGGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCATCATTGAC
AGTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCGACCATTTA
TAGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCAGTTACATGGTATAATCAG
GAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAATATCTTCCAAGTCATGCA
GTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTAAACAAGATATATTTAAAC
TACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGGAAGGTCATAGACCTTAGC
AACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTGGCTGATAATAACTGGCAG
TGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGCAACAGGTCTATAGGGAGT
GAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCATCGCATGAAAAGCCTCATA
AGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCCGGCTCTGGTCTCAGGAAG
AAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCTCCCCAGGACCTGGCTCTG
GCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTTGACAGACTGTGGCAAAAA
AAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCTGCGGGGCACACACCACAC
CCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACACAGCCACACCCACACGCC
ACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGCGGGGACAACACCGGGGCA
GGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATGTCAGCAGCGCAGGACCAC
ATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACATTCAGTGGGCGTCTCTTCT
GTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCCGGAGAAATAACAGCTTCC
CTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAGTCACTTTGGGACTCGCAG
ATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCCGGGGCAAGGGCTGAGGAA
GCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCAAGATGGGACAGTGGCCTG
GATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGTGACTGTGACTCTGATGAG
GGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGATGAGGAGTCCCTGCAGGAC
GAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACAATTCCAGGGAAATGCAAG
AATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAAAATGCCTCTGACACTGAT
AGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATGTTCACTTATGATTATGAC
ACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTTTTACAGCAAACACCACCA
TGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAAGAATCTTTCATTAAGGAA
ATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATCCTGAAGGAGACAACATGA
ATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGGTTATAAGCTAAACACACT
TGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTCCAAGAACCATGCACCATT
ATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATATTCAGAAGAGAATCTGTT
GCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCTCTGAAAAGAACAGCTTTA
GGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGAAGCACTTAAGTGGAAATG
CTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAATTGGAAAAGTTCTGAGTA

>In-frame_ENST00000434343_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52864103_length(amino acids)=737AA_start in transcript=1008_stop in transcript=3221
MVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLSGKEDLWEKLQYLWKVIDLSNNALIT
ILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAER
PQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKS
PGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSGNDG
AVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLT
HAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPAN
KEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPF
EKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVP

--------------------------------------------------------------
>In-frame_ENST00000602986_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52864103_length(transcript)=4367nt_BP=1713nt
ACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGA
GACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTG
TTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTC
TGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTC
TTGGATTTTAGGAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGA
CTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAG
CATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGG
ATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGGGTACTTTTTGACATCACACAAGAAGATGTT
TTGTTTCTGGCTTCACCTCTGACCTTCGATCCTTCTGTTGTGGAAATATTTCTTGCTCTATCAAGTGGTGCCTCTCTGCTTATTGTACCA
ACTTCCGTCAAGTTGCTCCCATCAAAATTAGCCAGCGTTCTCTTTTCCCATCATAGAGTGACTGTTTTGCAGGCAACACCAACATTGCTT
AGAAGATTTGGATCTCAGCTTATCAAGTCAACTGTTTTGTCAGCCACTACTTCTCTTCGAGTATTAGCCCTTGGTGGTGAAGCGTTTCCA
TCATTGACAGTTCTCAGAAGCTGGAGAGGAGAAGGCAATAAAACACAAATATTTAATGTTTATGGTATCACAGAGGTATCAAGTTGGGCG
ACCATTTATAGGATTCCAGAGAAGACTCTTAACTCTACTCTCAAATGTGAATTGCCTGTACAACTGGGATTTCCACTTCTTGGAACAGTA
GTTGAAGTCAGAGATACTAATGGCTTCACAATTCAGGAAGGCAGTGGCCAAGTATTTTTAGGTGGCAGAAACAGAGTGTGTTTTCTTGAT
GATGAAGTGACAGTACCACTTGGCACAATGCGAGCTACAGGAGACTTTGTGACTGTGAAAGATGGAGAGATTTTTTTTTTGGGACGAAAA
GACAGTCAGATCAAACGTCATGGCAAACGTCTTAACATTGAACTTGTGCAACAGGTTGCTGAAGAGCTTCAGCAAGTGGAGTCTTGTGCA
GTTACATGGTATAATCAGGAAAAATTAATTCTCTTCATGGTGTCTAAAGATGCTTCAGTAAAAGAATACATCTTTAAAGAACTGCAGAAA
TATCTTCCAAGTCATGCAGTCCCGGATGAGCTTGTATTGATCGACTCTCTACCATTTACATCCCACGGCAAAATTGATGTTTCTGAGTTA
AACAAGATATATTTAAACTACATAAACTTGAAGTCTGAGAATAAGCTCAGTGGGAAAGAGGACCTTTGGGAAAAATTACAGTATTTGTGG
AAGGTCATAGACCTTAGCAACAATGCTCTGATTACCATCCTACCAATGATGATCATAGCTCTAGAATTTCCCCATCTAGTGGTTGACTTG
GCTGATAATAACTGGCAGTGTGATGATAGTGTGGCAGTCTTTCAAAATTTTATTTCTGAATCCTGGAGGAAAAAGTGGAATGTCATTTGC
AACAGGTCTATAGGGAGTGAGGAGGCCAACGGGGGCACTCCCCAGAGCAGGATTTCCAGGGAAACCCGCCTTCCTCCCATTCATCTGCAT
CGCATGAAAAGCCTCATAAGGAGCAAAGCAGAGAGGCCCCAGGGAGGAAGGCACACGGGCATTTCTACTCTGGGGAAGAAGGCAAAGGCC
GGCTCTGGTCTCAGGAAGAAGCAGAGACGGCTGCCAAGGAGTGTTAGAAGCACCCGCGATGTGCAGGCTGCCGGCAAAAAAGAGGACGCT
CCCCAGGACCTGGCTCTGGCGGTGTGCCTGTCAGTGTTCATCACATTCCTTGTCGCCTTCAGCCTGGGGGCTTTCACAAGGCCTTATGTT
GACAGACTGTGGCAAAAAAAGTGCCAGAGCAAAAGCCCTGGCCTGGACAACGCGTATTCAAACGAGGGCTTCTACGATGACATGGAAGCT
GCGGGGCACACACCACACCCAGAGACCCATCTGCGCCAAGTATTTCCTCATCTAAGCCTCTACGAGAACCAGACCCCTTTCTGGGTGACA
CAGCCACACCCACACGCCACCGTAATTCCTGATAGAACTCTGGGAAGGAGCAGAAAGGATCCTGGCAGTTCGCAGAGCCCAGGACAGTGC
GGGGACAACACCGGGGCAGGAAGTGGAAATGATGGTGCAGTCTATTCCATTCTCCAGAGACATCCACATGCCGGTAACCGTGAACTAATG
TCAGCAGCGCAGGACCACATCCATAGGAATGATATTCTCGGAGAATGGACTTATGAAACTGTGGCCCAGGAAGAGCCTCTCAGTGCACAT
TCAGTGGGCGTCTCTTCTGTAGCTGGCACGTCTCACGCTGTCTCTGGCTCAAGCCGTTATGATTCCAATGAATTAGACCCTTCCCTCTCC
GGAGAAATAACAGCTTCCCTCTGTAAAATGCTAACACATGCAGAAGCACAGAGGACTGGAGATAGTAAGGAAAGAGGGGGCACTGAACAG
TCACTTTGGGACTCGCAGATGGAATTTTCTAAGGAAAGGCAAGTGAGTTCATCCATTGATTTGCTGAGCATACAGCAGCCAAGGCTGTCC
GGGGCAAGGGCTGAGGAAGCGCTTTCAGCCCACTACAGCGAGGTTCCATACGGTGACCCAAGAGACACAGGCCCATCAGTCTTTCCTCCA
AGATGGGACAGTGGCCTGGATGTCACTCCTGCTAACAAGGAACCAGTGCAGAAATCCACTCCTTCTGACACTTGCTGTGAGTTGGAGAGT
GACTGTGACTCTGATGAGGGGTCTCTGTTCACTCTGAGCTCCATAAGTTCAGAGAGTGCAAGGAGCAAGACTGAAGAGGCAGTGCCTGAT
GAGGAGTCCCTGCAGGACGAGAGCTCAGGGGCAAGCAAGGACAATGTGACGGCTGTAGACAGTCTTGAGGAAAATGTTACCTTCCAAACA
ATTCCAGGGAAATGCAAGAATCAAGAAGATCCCTTTGAAAAACCTCTCATTTCTGCTCCAGACTCTGGCATGTACAAGACTCATCTGGAA
AATGCCTCTGACACTGATAGATCTGAGGGCCTGTCACCCTGGCCCAGGTCACCAGGGAATAGTCCCTTAGGGGATGAGTTTCCGGGCATG
TTCACTTATGATTATGACACAGCTCTTCAATCCAAGGCAGCAGAATGGCATTGCTCACTTAGAGACTTAGAATTTTCAAATGTGGACGTT
TTACAGCAAACACCACCATGTTCTGCTGAAGTTCCCTCAGATCCTGATAAGGCTGCCTTCCATGAAAGAGACTCAGACATTTTAAAATAA
GAATCTTTCATTAAGGAAATATTCACAGCTCTAAACAATATTCTTTTAAAGATCATGGCAGGGGAAAACTAAAGCCTTCACAACAAGATC
CTGAAGGAGACAACATGAATTCCAACCAAGTGGACACTGATGCAAATGAGGGTTTTGTGGGCCCACTTGAGGGCGATGATTCTAGAAGGG
TTATAAGCTAAACACACTTGTTAACATCCTATGGGGATGAACCTGCTCTTCAGTGTGAAAGAGAAAGAGGGGAATATTTTGAGATCATTC
CAAGAACCATGCACCATTATTACAAGAGCTCCAAACAAAACCAGTTCACTGAGAACACAGGAGCACTTCATCAATAGGTTGGGGTAAATA
TTCAGAAGAGAATCTGTTGCAGTTAGACGAAGTGGTTCTAACTTTCCTTCTCAAATACAGACCTGGAGCAATCTGATGGGATTTGGCTCT
CTGAAAAGAACAGCTTTAGGATGACAAAGACAAGGATGTTCAACTTGATCATCAAAGAGAATTCAAATGACATTTTTTCATACATATTGA
AGCACTTAAGTGGAAATGCTGGATAGATTTTAATGAATTCTGAACACACACTAGCACAACTTTTTGGAGGCTGATCGTGAAACTGCAAAA

>In-frame_ENST00000602986_ENST00000343457_TCGA-06-2559-01A_AASDH_chr4_57217508_-_LRRC66_chr4_52864103_length(amino acids)=1118AA_start in transcript=333_stop in transcript=3689
MPTWDRLTLLDFRKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHCLAY
VLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVT
VLQATPTLLRRFGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCELPVQ
LGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAE
ELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLSGKED
LWEKLQYLWKVIDLSNNALITILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRE
TRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFS
LGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDP
GSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYD
SNELDPSLSGEITASLCKMLTHAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPR
DTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDS
LEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AASDH-LRRC66


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AASDH-LRRC66


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AASDH-LRRC66


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource