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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DUSP16-FAT1 (FusionGDB2 ID:24458)

Fusion Gene Summary for DUSP16-FAT1

check button Fusion gene summary
Fusion gene informationFusion gene name: DUSP16-FAT1
Fusion gene ID: 24458
HgeneTgene
Gene symbol

DUSP16

FAT1

Gene ID

80824

2195

Gene namedual specificity phosphatase 16FAT atypical cadherin 1
SynonymsMKP-7|MKP7CDHF7|CDHR8|FAT|ME5|hFat1
Cytomap

12p13.2

4q35.2

Type of geneprotein-codingprotein-coding
Descriptiondual specificity protein phosphatase 16MAP kinase phosphatase 7MAPK phosphatase-7mitogen-activated protein kinase phosphatase 7protocadherin Fat 1FAT tumor suppressor 1cadherin ME5cadherin family member 7cadherin-related family member 8cadherin-related tumor suppressor homologprotein fat homolog
Modification date2020031320200313
UniProtAcc

Q9BY84

Q14517

Ensembl transtripts involved in fusion geneENST00000228862, ENST00000298573, 
ENST00000545864, 		ENST00000441802, 
ENST00000512347, 
Fusion gene scores* DoF score9 X 6 X 6=3248 X 12 X 3=288
# samples 911
** MAII scorelog2(9/324*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/288*10)=-1.38856528791765
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DUSP16 [Title/Abstract] AND FAT1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDUSP16(12672796)-FAT1(187584767), # samples:1
Anticipated loss of major functional domain due to fusion event.DUSP16-FAT1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
DUSP16-FAT1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
DUSP16-FAT1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDUSP16

GO:0016311

dephosphorylation

24531476


check buttonFusion gene breakpoints across DUSP16 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across FAT1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-5803-01ADUSP16chr12

12672796

-FAT1chr4

187584767

-


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Fusion Gene ORF analysis for DUSP16-FAT1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000228862ENST00000441802DUSP16chr12

12672796

-FAT1chr4

187584767

-
5CDS-intronENST00000228862ENST00000512347DUSP16chr12

12672796

-FAT1chr4

187584767

-
Frame-shiftENST00000298573ENST00000441802DUSP16chr12

12672796

-FAT1chr4

187584767

-
5CDS-intronENST00000298573ENST00000512347DUSP16chr12

12672796

-FAT1chr4

187584767

-
intron-3CDSENST00000545864ENST00000441802DUSP16chr12

12672796

-FAT1chr4

187584767

-
intron-intronENST00000545864ENST00000512347DUSP16chr12

12672796

-FAT1chr4

187584767

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000228862DUSP16chr1212672796-ENST00000441802FAT1chr4187584767-12310999632115003622

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000228862ENST00000441802DUSP16chr1212672796-FAT1chr4187584767-0.0007222220.9992778

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Fusion Genomic Features for DUSP16-FAT1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for DUSP16-FAT1


check button Go to

FGviewer for the breakpoints of chr12:12672796-chr4:187584767

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DUSP16

Q9BY84

FAT1

Q14517

FUNCTION: Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2. {ECO:0000269|PubMed:11489891, ECO:0000269|PubMed:15888437}.FUNCTION: [Protocadherin Fat 1]: Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021271140_12451088.33333333333334589.0DomainCadherin 10
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021271246_13571088.33333333333334589.0DomainCadherin 11
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021271359_14561088.33333333333334589.0DomainCadherin 12
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021271457_15621088.33333333333334589.0DomainCadherin 13
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021271563_16671088.33333333333334589.0DomainCadherin 14
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021271668_17651088.33333333333334589.0DomainCadherin 15
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021271766_18791088.33333333333334589.0DomainCadherin 16
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021271880_19791088.33333333333334589.0DomainCadherin 17
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021271980_20811088.33333333333334589.0DomainCadherin 18
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021272082_21821088.33333333333334589.0DomainCadherin 19
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021272183_22831088.33333333333334589.0DomainCadherin 20
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021272284_23901088.33333333333334589.0DomainCadherin 21
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021272391_24921088.33333333333334589.0DomainCadherin 22
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021272493_25961088.33333333333334589.0DomainCadherin 23
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021272597_27031088.33333333333334589.0DomainCadherin 24
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021272704_28091088.33333333333334589.0DomainCadherin 25
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021272810_29181088.33333333333334589.0DomainCadherin 26
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021272919_30231088.33333333333334589.0DomainCadherin 27
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021273024_31251088.33333333333334589.0DomainCadherin 28
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021273126_32301088.33333333333334589.0DomainCadherin 29
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021273231_33351088.33333333333334589.0DomainCadherin 30
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021273336_34401088.33333333333334589.0DomainCadherin 31
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021273441_35451088.33333333333334589.0DomainCadherin 32
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021273546_36471088.33333333333334589.0DomainCadherin 33
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021273790_38271088.33333333333334589.0DomainEGF-like 1
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021273829_40091088.33333333333334589.0DomainLaminin G-like
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021274013_40501088.33333333333334589.0DomainEGF-like 2
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021274052_40881088.33333333333334589.0DomainEGF-like 3
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021274089_41251088.33333333333334589.0DomainEGF-like 4
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021274127_41631088.33333333333334589.0DomainEGF-like 5%3B calcium-binding
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021274204_42141088.33333333333334589.0MotifNuclear localization signal
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021274378_43821088.33333333333334589.0MotifPTB-like motif
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021274203_45881088.33333333333334589.0Topological domainCytoplasmic
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021274182_42021088.33333333333334589.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDUSP16chr12:12672796chr4:187584767ENST00000228862-37158_300122.33333333333333666.0DomainTyrosine-protein phosphatase
HgeneDUSP16chr12:12672796chr4:187584767ENST00000228862-3722_137122.33333333333333666.0DomainRhodanese
TgeneFAT1chr12:12672796chr4:187584767ENST000004418021271035_11391088.33333333333334589.0DomainCadherin 9
TgeneFAT1chr12:12672796chr4:187584767ENST00000441802127150_2571088.33333333333334589.0DomainCadherin 2
TgeneFAT1chr12:12672796chr4:187584767ENST0000044180212735_1491088.33333333333334589.0DomainCadherin 1
TgeneFAT1chr12:12672796chr4:187584767ENST00000441802127368_4631088.33333333333334589.0DomainCadherin 3
TgeneFAT1chr12:12672796chr4:187584767ENST00000441802127464_5691088.33333333333334589.0DomainCadherin 4
TgeneFAT1chr12:12672796chr4:187584767ENST00000441802127570_6731088.33333333333334589.0DomainCadherin 5
TgeneFAT1chr12:12672796chr4:187584767ENST00000441802127718_8221088.33333333333334589.0DomainCadherin 6
TgeneFAT1chr12:12672796chr4:187584767ENST00000441802127823_9271088.33333333333334589.0DomainCadherin 7
TgeneFAT1chr12:12672796chr4:187584767ENST00000441802127928_10341088.33333333333334589.0DomainCadherin 8
TgeneFAT1chr12:12672796chr4:187584767ENST0000044180212722_41811088.33333333333334589.0Topological domainExtracellular


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Fusion Gene Sequence for DUSP16-FAT1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000228862_ENST00000441802_TCGA-CD-5803-01A_DUSP16_chr12_12672796_-_FAT1_chr4_187584767_length(transcript)=12310nt_BP=999nt
GGAAGAGAAAGAGTGAAGAAAAGTTGCGAGCGTCTCCTCTCTTCCTAAGCCTCCCGCCCCAACCCACCCCTCAGAGAAGGAGAAGATAAT
ATACTGAAAAGAAGAGGAGGAGGAGAGCGACGGGACGGGACGCGAGCGGGAGCGCAGCCGCCCTCTCGGCTCCGCGGCGGCGCCTCGCAA
GTCCGGGAGGCGAGGGGGGCCCGAGGGGAGACGCCGTGACAACTTTCGTTTCCCTCTGAGGGAATTGGGAGGTCGGCGGCCCCAAAAGCT
TTCAGTCCAGTGTAAAGCTGTTGGAGCGCGGGAGCAAAGGTAAAGAATGATGTAATGCGCTGGCTGCTCCAAAGCATCTTTTGTTGTGGA
ATGGTTATTCCAGTCATCTCTTTATGAATCAAATGTGAGGGGCTGCTTTGTGGACGGAGTCCTTTGCAAGAGCACATCAACGGGAAAGAG
AAAGAGACATTCACTTGGAGGGCTCTTGCTGAAAATGGGTTTAACTCTCCTTTTGCCAGTCACCACCAGCCTGACCTCATACACTTTTAG
TACAATGGAGTGGCTGAGCCTTTGAGCACACCACCATTACATCATCGTGGCAAATTAAAGAAGGAGGTGGGAAAAGAGGACTTATTGTTG
TCATGGCCCATGAGATGATTGGAACTCAAATTGTTACTGAGAGGTTGGTGGCTCTGCTGGAAAGTGGAACGGAAAAAGTGCTGCTAATTG
ATAGCCGGCCATTTGTGGAATACAATACATCCCACATTTTGGAAGCCATTAATATCAACTGCTCCAAGCTTATGAAGCGAAGGTTGCAAC
AGGACAAAGTGTTAATTACAGAGCTCATCCAGCATTCAGCGAAACATAAGGTTGACATTGATTGCAGTCAGAAGGTTGTAGTTTACGATC
AAAGCTCCCAAGATGTTGCCTCTCTCTCTTCAGACTGTTTTCTCACTGTACTTCTGGGTAAACTGGAGAAGAGCTTCAACTCTGTTCACC
TGCTTGCAGGTGTCATAGAGACGTCAGATCGACTGGACCGTGAATCGACCTCCCATTATTGGCTAACAGTCTTTGCAACCGATCAGGGTG
TCGTGCCTCTTTCATCGTTCATAGAGATCTACATAGAGGTTGAGGATGTCAATGACAATGCACCACAGACATCAGAGCCTGTTTATTACC
CAGAAATCATGGAAAATTCTCCTAAAGATGTATCTGTGGTCCAGATCGAGGCATTTGATCCAGATTCGAGCTCTAATGACAAGCTCATGT
ACAAAATTACAAGTGGAAATCCACAAGGATTCTTTTCAATACATCCTAAAACAGGTCTCATCACAACTACGTCAAGGAAGCTAGACCGAG
AACAGCAAGATGAACACATATTAGAGGTTACTGTGACAGACAATGGTAGTCCCCCCAAATCAACCATTGCAAGAGTCATTGTGAAAATCC
TTGATGAAAATGACAACAAACCTCAGTTTCTGCAAAAGTTCTACAAAATCAGACTCCCTGAGCGGGAAAAGCCAGACCGAGAAAGAAATG
CCAGACGGGAGCCGCTCTATCACGTCATAGCCACCGACAAGGATGAGGGCCCCAATGCAGAAATCTCCTACAGCATCGAAGACGGGAATG
AGCATGGCAAATTTTTCATCGAACCGAAAACTGGAGTGGTTTCGTCCAAGAGGTTTTCAGCAGCTGGAGAATATGATATTCTTTCAATTA
AGGCAGTTGACAATGGTCGCCCTCAAAAGTCATCAACCACCAGACTCCATATTGAATGGATCTCCAAGCCCAAACCGTCCCTGGAGCCCA
TTTCATTTGAAGAATCATTTTTTACCTTTACTGTGATGGAAAGTGACCCCGTTGCTCACATGATTGGAGTAATATCTGTGGAGCCTCCTG
GCATACCCCTTTGGTTTGACATCACTGGTGGCAACTACGACAGTCACTTCGATGTGGACAAGGGAACTGGAACCATCATTGTTGCCAAAC
CTCTTGATGCAGAACAGAAGTCAAACTACAACCTCACAGTCGAGGCTACAGATGGAACCACCACTATCCTCACTCAGGTATTCATCAAAG
TAATAGACACAAATGACCATCGTCCTCAGTTTTCTACATCAAAGTATGAAGTTGTTATTCCTGAAGATACAGCGCCAGAAACAGAAATTT
TGCAAATCAGTGCTGTGGATCAGGATGAGAAAAACAAACTAATCTACACTCTGCAGAGCAGTAGAGATCCACTGAGTCTCAAGAAATTTC
GTCTTGATCCTGCAACCGGCTCTCTCTATACTTCTGAGAAACTGGATCATGAAGCTGTTCACCAGCACACCCTCACGGTCATGGTACGAG
ATCAAGATGTGCCTGTAAAACGCAACTTTGCAAGGATTGTGGTCAATGTCAGCGACACGAATGACCACGCCCCGTGGTTCACCGCTTCCT
CCTACAAAGGGCGGGTTTATGAATCGGCAGCCGTTGGCTCAGTTGTGTTGCAGGTGACGGCTCTGGACAAGGACAAAGGGAAAAATGCTG
AAGTGCTGTACTCGATCGAGTCAGGAAATATTGGAAATTCTTTTATGATTGATCCTGTCTTGGGCTCTATTAAAACTGCCAAAGAATTAG
ATCGAAGTAACCAAGCGGAGTATGATTTAATGGTAAAAGCTACAGATAAGGGCAGTCCACCAATGAGTGAAATAACTTCTGTGCGTATCT
TTGTCACAATTGCTGACAACGCCTCTCCGAAGTTTACATCAAAAGAATATTCTGTTGAACTTAGTGAAACTGTCAGCATTGGGAGTTTCG
TTGGGATGGTTACAGCCCATAGTCAATCATCAGTGGTGTATGAAATAAAAGATGGAAATACAGGTGATGCTTTTGATATTAATCCACATT
CTGGAACTATCATCACTCAGAAAGCCCTGGACTTTGAAACTTTGCCCATTTACACATTGATAATACAAGGAACTAACATGGCTGGTTTGT
CCACTAATACAACGGTTCTAGTTCACTTGCAGGATGAGAATGACAACGCGCCAGTTTTTATGCAGGCAGAATATACAGGACTCATTAGTG
AATCAGCCTCAATTAACAGCGTGGTCCTAACAGACAGGAATGTCCCACTGGTGATTCGAGCAGCTGATGCTGATAAAGACTCAAATGCTT
TGCTTGTATATCACATTGTTGAACCATCTGTACACACATATTTTGCTATTGATTCTAGCACTGGTGCTATTCATACAGTACTAAGTCTGG
ACTATGAAGAAACAAGTATTTTTCACTTTACCGTCCAAGTGCATGACATGGGAACCCCACGTTTATTTGCTGAGTATGCAGCGAATGTAA
CAGTACATGTAATTGACATTAATGACTGCCCCCCTGTGTTTGCCAAGCCATTATATGAAGCATCTCTTTTGTTACCAACATACAAAGGAG
TAAAAGTCATCACAGTAAATGCTACAGATGCTGATTCAAGTGCATTCTCACAGTTGATTTACTCCATCACCGAAGGCAACATCGGGGAGA
AGTTTTCTATGGACTACAAGACTGGTGCTCTCACTGTCCAAAACACAACTCAGTTAAGAAGCCGCTACGAGCTAACCGTTAGAGCTTCCG
ATGGCAGATTTGCCGGCCTTACCTCTGTCAAAATTAATGTGAAAGAAAGCAAAGAAAGTCACCTAAAGTTTACCCAGGATGTCTACTCTG
CGGTAGTGAAAGAGAATTCCACCGAGGCCGAAACATTAGCTGTCATTACTGCTATTGGGAATCCAATCAATGAGCCTTTGTTTTATCACA
TCCTCAACCCAGATCGCAGATTTAAAATAAGCCGCACTTCAGGAGTTCTGTCAACCACTGGCACGCCCTTCGATCGTGAGCAGCAGGAGG
CGTTTGATGTGGTTGTAGAAGTGACAGAGGAACATAAGCCTTCTGCAGTGGCCCACGTTGTCGTGAAGGTCATTGTAGAAGACCAAAATG
ATAATGCGCCGGTGTTTGTCAACCTTCCCTACTACGCCGTTGTTAAAGTGGACACTGAGGTGGGCCATGTCATTCGCTATGTCACTGCTG
TAGACAGAGACAGTGGCAGAAACGGGGAAGTGCATTACTACCTCAAGGAACATCATGAACACTTTCAAATTGGACCCTTGGGTGAAATTT
CACTGAAAAAGCAATTTGAGCTTGACACCTTAAATAAAGAATATCTTGTTACAGTGGTTGCAAAAGATGGAGGGAACCCGGCCTTTTCAG
CGGAAGTTATCGTTCCGATCACTGTCATGAATAAAGCCATGCCTGTGTTTGAAAAACCTTTCTACAGTGCAGAGATTGCAGAGAGCATCC
AGGTGCACAGCCCTGTGGTCCACGTGCAGGCTAACAGCCCGGAAGGCCTGAAAGTGTTCTACAGCATCACAGACGGAGACCCTTTCAGCC
AGTTCACTATTAACTTCAATACTGGAGTTATCAATGTCATAGCTCCTCTGGACTTTGAGGCCCACCCGGCATATAAGCTGAGCATACGCG
CAACTGACTCCTTGACGGGCGCTCATGCTGAAGTATTTGTGGACATCATAGTAGACGACATCAATGATAACCCTCCTGTGTTTGCTCAGC
AGTCTTATGCGGTGACCCTGTCTGAGGCATCTGTAATTGGAACGTCTGTTGTTCAAGTTAGAGCCACCGATTCTGATTCAGAACCAAATA
GAGGAATCTCATACCAGATGTTTGGGAATCACAGCAAGAGTCATGATCATTTTCATGTAGACAGCAGCACTGGCCTCATCTCACTACTCA
GAACCCTGGATTACGAGCAGTCCCGGCAGCACACGATTTTTGTGAGGGCAGTTGATGGTGGTATGCCCACGCTGAGCAGTGATGTGATTG
TCACGGTGGACGTTACCGACCTCAATGATAATCCACCACTCTTTGAACAACAGATTTATGAAGCCAGAATTAGCGAGCACGCCCCTCATG
GGCATTTCGTGACCTGTGTAAAAGCCTATGATGCAGACAGTTCAGACATAGACAAGTTGCAGTATTCCATTCTGTCTGGCAATGATCATA
AACATTTTGTCATTGACAGTGCAACAGGGATTATCACCCTCTCAAACCTGCACCGGCACGCCCTGAAGCCATTTTACAGTCTTAACCTGT
CAGTGTCTGATGGAGTTTTTAGAAGTTCCACCCAGGTTCATGTAACTGTAATTGGAGGCAATTTGCACAGTCCTGCTTTCCTTCAGAACG
AATATGAAGTGGAACTAGCTGAAAACGCTCCCCTACATACCCTGGTGATGGAGGTGAAAACTACGGATGGGGATTCTGGTATTTATGGTC
ACGTTACTTACCATATTGTAAATGACTTTGCCAAAGACAGATTTTACATAAATGAGAGAGGACAGATATTTACTTTGGAAAAACTTGATC
GAGAAACCCCGGCGGAGAAAGTGATCTCAGTCCGTTTAATGGCTAAGGATGCTGGAGGAAAAGTTGCTTTCTGCACCGTGAATGTCATCC
TTACAGATGACAATGACAATGCACCACAATTTCGAGCAACCAAATACGAAGTGAATATCGGGTCCAGTGCTGCTAAAGGGACTTCAGTCG
TTAAAGTTCTTGCAAGTGATGCCGATGAGGGCTCCAATGCCGACATCACCTATGCCATTGAAGCAGACTCTGAAAGTGTAAAAGAGAATT
TGGAAATTAACAAACTGTCCGGCGTAATCACTACAAAGGAGAGCCTCATTGGCTTGGAAAATGAATTCTTCACTTTCTTTGTTAGAGCTG
TGGATAATGGGTCTCCATCAAAAGAATCTGTTGTTCTTGTCTATGTTAAAATCCTTCCACCGGAAATGCAGCTTCCAAAATTTTCAGAAC
CTTTCTATACCTTTACAGTGTCAGAGGACGTGCCTATTGGAACAGAGATAGATCTCATCCGAGCAGAACATAGTGGGACTGTTCTTTACA
GCCTGGTCAAAGGGAATACTCCAGAAAGCAATAGGGATGAGTCCTTTGTGATTGACAGACAGAGCGGGAGACTGAAGTTGGAGAAGAGTC
TTGATCATGAGACAACTAAGTGGTATCAGTTTTCCATACTGGCCAGGTGCACTCAAGATGACCATGAGATGGTGGCTTCTGTAGATGTTA
GTATCCAAGTGAAAGATGCAAATGACAACAGCCCGGTCTTTGAATCTAGTCCATATGAGGCATTCATTGTTGAAAACCTGCCAGGGGGAA
GTAGAGTAATTCAGATCAGGGCATCTGATGCTGACTCAGGAACCAACGGCCAAGTTATGTATAGCCTGGATCAGTCACAAAGTGTGGAAG
TCATTGAATCCTTTGCCATTAACATGGAAACAGGCTGGATTACAACTTTAAAGGAACTTGACCATGAAAAGAGAGACAATTACCAGATTA
AAGTGGTTGCATCAGATCATGGTGAAAAGATCCAGCTATCCTCCACAGCCATTGTGGATGTTACCGTCACCGATGTCAACGATAGTCCAC
CACGATTCACGGCCGAGATCTATAAAGGGACTGTGAGTGAGGATGACCCCCAAGGTGGGGTGATTGCCATCTTAAGTACCACGGATGCTG
ATTCTGAAGAGATCAACAGACAAGTTACATATTTCATAACAGGAGGGGATCCTTTAGGACAGTTTGCCGTTGAAACTATACAGAATGAAT
GGAAGGTATATGTGAAGAAACCTCTAGACAGGGAAAAAAGGGACAATTACCTTCTTACTATCACGGCAACTGATGGCACCTTCTCATCAA
AAGCGATAGTTGAAGTGAAAGTTCTGGATGCAAATGACAACAGTCCAGTTTGTGAAAAGACTTTATATTCAGACACTATTCCTGAAGACG
TCCTTCCTGGAAAATTGATCATGCAGATCTCTGCTACAGACGCAGACATCCGCTCTAACGCTGAAATTACTTACACGTTATTGGGTTCAG
GTGCAGAAAAATTCAAACTAAATCCAGACACAGGTGAACTGAAAACGTCAACCCCCCTTGATCGTGAGGAGCAAGCTGTTTATCATCTTC
TCGTCAGGGCCACAGATGGAGGAGGAAGATTCTGCCAAGCCAGTATTGTGCTCACGCTAGAAGATGTGAACGATAACGCCCCCGAATTCT
CTGCCGATCCTTATGCCATCACCGTGTTTGAAAACACAGAGCCGGGAACGCTGCTGACAAGAGTGCAGGCCACAGATGCCGACGCAGGAT
TAAATCGGAAGATTTTATACTCACTGATTGACTCTGCTGATGGGCAGTTCTCCATTAACGAATTATCTGGAATTATTCAGTTAGAAAAAC
CTTTGGACAGAGAACTCCAGGCAGTATACACCCTCTCTTTGAAAGCTGTGGATCAAGGCTTGCCAAGGAGGCTGACTGCCACTGGCACTG
TGATTGTATCAGTTCTTGACATAAATGACAACCCCCCTGTGTTTGAGTACCGTGAATATGGTGCCACCGTGTCTGAGGACATTCTTGTTG
GAACTGAAGTTCTTCAAGTGTATGCAGCAAGTCGGGATATTGAAGCAAATGCAGAAATCACCTACTCAATAATAAGTGGAAATGAACATG
GGAAATTCAGCATAGATTCTAAAACAGGGGCCGTATTTATCATTGAGAATCTGGATTATGAGAGCTCTCATGAGTATTACCTAACAGTAG
AGGCCACTGATGGAGGCACGCCTTCACTGAGCGACGTTGCCACTGTGAACGTTAATGTAACAGATATCAACGATAATACCCCTGTGTTCA
GCCAAGACACCTACACGACAGTCATCAGTGAAGATGCCGTTCTTGAGCAGTCTGTCATCACGGTTATGGCCGATGATGCCGATGGACCTT
CCAACAGCCACATCCACTACTCAATTATAGATGGCAACCAAGGAAGCTCGTTCACAATTGACCCCGTCAGGGGAGAAGTCAAAGTGACCA
AACTTCTCGACCGAGAAACGATTTCAGGTTACACGCTCACGGTTCAAGCTTCTGATAATGGCAGTCCACCCAGAGTCAACACGACGACCG
TGAACATCGATGTGTCCGATGTCAATGACAACGCGCCCGTCTTCTCCAGGGGAAACTACAGTGTCATTATCCAGGAAAATAAGCCAGTGG
GCTTCAGCGTGCTGCAGCTGGTAGTAACAGATGAGGATTCTTCCCATAACGGTCCACCCTTCTTCTTTACTATTGTAACTGGAAATGATG
AGAAGGCTTTTGAAGTTAACCCGCAAGGAGTCCTCCTGACATCATCTGCCATCAAGAGGAAGGAGAAAGATCATTACTTACTGCAGGTGA
AGGTGGCAGATAATGGAAAGCCTCAGTTGTCATCTTTGACATACATTGACATTAGGGTAATTGAGGAGAGCATCTATCCGCCTGCGATTT
TGCCCCTGGAGATTTTCATCACCTCTTCTGGAGAAGAATACTCAGGTGGCGTCATTGGGAAGATCCATGCCACAGACCAGGACGTGTATG
ATACTCTAACCTACAGTCTCGACCCTCAGATGGACAACCTGTTCTCTGTTTCCAGCACAGGGGGCAAGCTGATAGCACACAAAAAGCTAG
ACATAGGGCAATACCTTCTCAATGTCAGCGTAACAGATGGGAAGTTCACGACGGTGGCCGACATCACAGTGCATATCAGACAAGTCACAC
AGGAGATGTTGAACCACACCATCGCGATCCGCTTTGCCAACCTCACTCCGGAAGAATTCGTTGGTGACTACTGGCGCAACTTCCAGCGAG
CTTTACGGAACATCCTGGGTGTGAGGAGGAACGACATACAGATTGTTAGTTTGCAGTCCTCTGAACCTCACCCACATCTGGACGTCTTAC
TTTTTGTAGAGAAACCAGGTAGTGCTCAGATCTCAACAAAACAACTTCTGCACAAGATTAACTCTTCCGTGACTGACATTGAGGAAATCA
TTGGAGTTAGGATACTGAATGTATTCCAGAAACTCTGCGCGGGACTGGACTGCCCCTGGAAGTTCTGCGATGAAAAGGTGTCTGTGGATG
AAAGTGTGATGTCAACACACAGCACAGCCAGACTGAGTTTTGTGACTCCCCGCCACCACAGGGCAGCGGTGTGTCTCTGCAAAGAGGGAA
GGTGCCCACCTGTCCACCATGGCTGTGAAGATGATCCGTGCCCTGAGGGATCCGAATGTGTGTCTGATCCCTGGGAGGAGAAACACACCT
GTGTCTGTCCCAGCGGCAGGTTTGGTCAGTGCCCAGGGAGTTCATCTATGACACTGACTGGAAACAGCTACGTGAAATACCGTCTGACGG
AAAATGAAAACAAATTAGAGATGAAACTGACCATGAGGCTCAGAACATATTCCACGCATGCGGTTGTCATGTATGCTCGAGGAACTGACT
ATAGCATCTTGGAGATTCATCATGGAAGGCTGCAGTACAAGTTTGACTGTGGAAGTGGCCCTGGAATTGTCTCTGTTCAGAGCATTCAGG
TCAATGATGGGCAGTGGCACGCAGTGGCCCTGGAAGTGAATGGAAACTATGCTCGCTTGGTTCTAGACCAAGTTCATACTGCATCGGGCA
CAGCCCCAGGGACTCTGAAAACCCTGAACCTGGATAACTATGTGTTTTTTGGTGGCCACATCCGTCAGCAGGGAACAAGGCATGGAAGAA
GTCCTCAAGTTGGTAATGGTTTCAGGGGTTGTATGGACTCCATTTATTTGAATGGGCAGGAGCTCCCTTTAAACAGCAAACCCAGAAGCT
ATGCACACATCGAAGAGTCGGTGGATGTATCTCCAGGCTGCTTCCTGACGGCCACGGAAGACTGCGCCAGCAACCCTTGCCAGAATGGAG
GCGTTTGCAATCCGTCACCTGCTGGAGGTTATTACTGCAAATGCAGTGCCTTGTACATAGGGACCCACTGTGAGATAAGCGTCAATCCGT
GTTCCTCCAAGCCATGCCTCTATGGGGGCACGTGTGTTGTCGACAACGGAGGCTTTGTTTGCCAGTGTAGAGGATTATATACTGGTCAGA
GGTGTCAGCTTAGTCCATACTGCAAAGATGAACCCTGTAAGAATGGCGGAACATGCTTTGACAGTTTGGATGGCGCCGTTTGTCAGTGTG
ATTCGGGTTTTAGGGGAGAAAGGTGTCAGAGTGATATCGACGAGTGCTCTGGAAACCCTTGCCTGCACGGGGCCCTCTGTGAGAACACGC
ACGGCTCCTATCACTGCAACTGCAGCCACGAGTACAGGGGACGTCACTGCGAGGATGCTGCGCCCAACCAGTATGTGTCCACGCCGTGGA
ACATTGGGTTGGCGGAAGGAATTGGAATCGTTGTGTTTGTTGCAGGGATATTTTTACTGGTGGTGGTGTTTGTTCTCTGCCGTAAGATGA
TTAGTCGGAAAAAGAAGCATCAGGCTGAACCTAAAGACAAGCACCTGGGACCCGCTACGGCTTTCTTGCAAAGACCGTATTTTGATTCCA
AGCTAAATAAGAACATTTACTCAGACATACCACCCCAGGTGCCTGTCCGGCCTATTTCCTACACCCCGAGTATTCCAAGTGACTCAAGAA
ACAATCTGGACCGAAATTCCTTCGAAGGATCTGCTATCCCAGAGCATCCCGAATTCAGCACTTTTAACCCCGAGTCTGTGCACGGGCACC
GAAAAGCAGTGGCGGTCTGCAGCGTGGCGCCAAACCTGCCTCCCCCACCCCCTTCAAACTCCCCTTCTGACAGCGACTCCATCCAGAAGC
CTAGCTGGGACTTTGACTATGACACAAAAGTGGTGGATCTTGATCCCTGTCTTTCCAAGAAGCCTCTAGAGGAAAAGCCTTCCCAGCCAT
ACAGTGCCCGGGAAAGCCTGTCTGAAGTGCAGTCTCTGAGCTCCTTCCAGTCCGAATCGTGCGATGACAATGGGTATCACTGGGATACAT
CAGATTGGATGCCAAGCGTTCCTCTGCCGGACATACAAGAGTTCCCCAACTATGAGGTGATTGATGAGCAGACACCCCTGTACTCAGCAG
ATCCAAACGCCATCGATACGGACTATTACCCTGGAGGCTACGACATCGAAAGTGATTTTCCTCCACCCCCAGAAGACTTCCCCGCAGCTG
ATGAGCTACCACCGTTACCGCCCGAATTCAGCAATCAGTTTGAATCCATCCACCCTCCTAGAGACATGCCTGCCGCGGGTAGCTTGGGTT
CTTCATCAAGAAACCGGCAGAGGTTCAACTTGAATCAGTATTTGCCCAATTTTTATCCCCTCGATATGTCTGAACCTCAAACAAAAGGCA
CTGGTGAGAATAGTACTTGTAGAGAACCCCATGCCCCTTACCCGCCAGGGTATCAAAGACACTTCGAGGCGCCCGCTGTCGAGAGCATGC
CCATGTCTGTGTACGCCTCCACCGCCTCCTGCTCTGACGTGTCAGCCTGCTGCGAAGTGGAGTCCGAGGTCATGATGAGTGACTATGAGA
GCGGGGACGACGGCCACTTCGAAGAGGTGACGATCCCGCCCCTGGATTCCCAGCAGCACACGGAAGTCTGACTCTCAACTCCCCCCAAAG
TGCCTGACTTTAGTGAACCTAGAGGTGATGTGAGTAATCCGCGCTGTTCTTTGCAGCAGTGCTTCCAAGCTTTTTTTGGTGAGCCGAATG
GGCATGGCTGCGCTGGATCCTGCGCCTCTGGACGTGCTAGCCATTTCCAGTGTCCCAACTACTGTCATCGTGAGGTTTTCATCGGCTGTG
CCATTTCCCAACGTCTTTTGGGATTTACATCTGTCTGTGTTAAAATAATCAAACGAAAAATCAGTCCTGTGTTGTCAGCATGATTCATGT
ATTTATATAGATTTGATTATTTTAATTTTCCTGTCTCTTTTTTTTGTAAATTTTATGTACAGATTTGATTTTTCATAGTTTTAACTAGAT
TTCCAAGATATTTTGTGCATTTGTTTCAACTGAATTTTGGTGGTGTCAGTGCCATTATCTAGCACCCTGATTTTTTTTTTTTTACTATAA
CCAGGGTTTCATTCTGTCTTTTTCCACTGAAGTGTGACATTTTGTTAGTACATTTCAGTGTAGTCATTCATTTCTAGCTGTACATAGGAT
GAAGGAGAGATCAGATACATGAACATGTCTTACATGGGTTGCTGTATTTAGAATTATAAACATTTTTCATTATTGGAAAGTGTAACGGGG
ACCTTCTGCATACCTGTTTAGAACCAAAACCACCATGACACAGTTTTTATAGTGTCTGTATATTTGTGATGCAATGGTCTTGTAAAGGTT

>In-frame_ENST00000228862_ENST00000441802_TCGA-CD-5803-01A_DUSP16_chr12_12672796_-_FAT1_chr4_187584767_length(amino acids)=3622AA_start in transcript=632_stop in transcript=11500
MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCSQKVVVYDQ
SSQDVASLSSDCFLTVLLGKLEKSFNSVHLLAGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYP
EIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKIL
DENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRFSAAGEYDILSIK
AVDNGRPQKSSTTRLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIPLWFDITGGNYDSHFDVDKGTGTIIVAKP
LDAEQKSNYNLTVEATDGTTTILTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKLIYTLQSSRDPLSLKKFR
LDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAE
VLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFV
GMVTAHSQSSVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISE
SASINSVVLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAEYAANVT
VHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITEGNIGEKFSMDYKTGALTVQNTTQLRSRYELTVRASD
GRFAGLTSVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGNPINEPLFYHILNPDRRFKISRTSGVLSTTGTPFDREQQEA
FDVVVEVTEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKEHHEHFQIGPLGEIS
LKKQFELDTLNKEYLVTVVAKDGGNPAFSAEVIVPITVMNKAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPEGLKVFYSITDGDPFSQ
FTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNR
GISYQMFGNHSKSHDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISEHAPHG
HFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIITLSNLHRHALKPFYSLNLSVSDGVFRSSTQVHVTVIGGNLHSPAFLQNE
YEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYINERGQIFTLEKLDRETPAEKVISVRLMAKDAGGKVAFCTVNVIL
TDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAV
DNGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPIGTEIDLIRAEHSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSL
DHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQSVEV
IESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDAD
SEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATDGTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDV
LPGKLIMQISATDADIRSNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGGRFCQASIVLTLEDVNDNAPEFS
ADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTV
IVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHEYYLTVE
ATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTK
LLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDE
KAFEVNPQGVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLEIFITSSGEEYSGGVIGKIHATDQDVYD
TLTYSLDPQMDNLFSVSSTGGKLIAHKKLDIGQYLLNVSVTDGKFTTVADITVHIRQVTQEMLNHTIAIRFANLTPEEFVGDYWRNFQRA
LRNILGVRRNDIQIVSLQSSEPHPHLDVLLFVEKPGSAQISTKQLLHKINSSVTDIEEIIGVRILNVFQKLCAGLDCPWKFCDEKVSVDE
SVMSTHSTARLSFVTPRHHRAAVCLCKEGRCPPVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQCPGSSSMTLTGNSYVKYRLTE
NENKLEMKLTMRLRTYSTHAVVMYARGTDYSILEIHHGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLDQVHTASGT
APGTLKTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDVSPGCFLTATEDCASNPCQNGG
VCNPSPAGGYYCKCSALYIGTHCEISVNPCSSKPCLYGGTCVVDNGGFVCQCRGLYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCD
SGFRGERCQSDIDECSGNPCLHGALCENTHGSYHCNCSHEYRGRHCEDAAPNQYVSTPWNIGLAEGIGIVVFVAGIFLLVVVFVLCRKMI
SRKKKHQAEPKDKHLGPATAFLQRPYFDSKLNKNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPESVHGHR
KAVAVCSVAPNLPPPPPSNSPSDSDSIQKPSWDFDYDTKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDDNGYHWDTS
DWMPSVPLPDIQEFPNYEVIDEQTPLYSADPNAIDTDYYPGGYDIESDFPPPPEDFPAADELPPLPPEFSNQFESIHPPRDMPAAGSLGS
SSRNRQRFNLNQYLPNFYPLDMSEPQTKGTGENSTCREPHAPYPPGYQRHFEAPAVESMPMSVYASTASCSDVSACCEVESEVMMSDYES

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Fusion Gene PPI Analysis for DUSP16-FAT1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DUSP16-FAT1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DUSP16-FAT1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneDUSP16C0023893Liver Cirrhosis, Experimental1CTD_human
TgeneFAT1C0009402Colorectal Carcinoma1CTD_human
TgeneFAT1C0009404Colorectal Neoplasms1CTD_human
TgeneFAT1C0010606Adenoid Cystic Carcinoma1CTD_human
TgeneFAT1C0017636Glioblastoma1CTD_human
TgeneFAT1C0018671Head and Neck Neoplasms1CTD_human
TgeneFAT1C0018675Head Neoplasms1CTD_human
TgeneFAT1C0023893Liver Cirrhosis, Experimental1CTD_human
TgeneFAT1C0027533Neck Neoplasms1CTD_human
TgeneFAT1C0036095Salivary Gland Neoplasms1CTD_human
TgeneFAT1C0220636Malignant neoplasm of salivary gland1CTD_human
TgeneFAT1C0278996Malignant Head and Neck Neoplasm1CTD_human
TgeneFAT1C0279626Squamous cell carcinoma of esophagus1CTD_human
TgeneFAT1C0334588Giant Cell Glioblastoma1CTD_human
TgeneFAT1C0746787Cancer of Neck1CTD_human
TgeneFAT1C0751177Cancer of Head1CTD_human
TgeneFAT1C0887900Upper Aerodigestive Tract Neoplasms1CTD_human
TgeneFAT1C1621958Glioblastoma Multiforme1CTD_human