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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ELN-METTL2A (FusionGDB2 ID:26254)

Fusion Gene Summary for ELN-METTL2A

check button Fusion gene summary
Fusion gene informationFusion gene name: ELN-METTL2A
Fusion gene ID: 26254
HgeneTgene
Gene symbol

ELN

METTL2A

Gene ID

100130933

339175

Gene namesmall integral membrane protein 6methyltransferase like 2A
SynonymsC17orf110|ELNMETTL2
Cytomap

17q25.1

17q23.2

Type of geneprotein-codingprotein-coding
Descriptionsmall integral membrane protein 6endoregulintRNA N(3)-methylcytidine methyltransferase METTL2Amethyltransferase-like protein 2A
Modification date2020031320200313
UniProtAcc.

Q96IZ6

Ensembl transtripts involved in fusion geneENST00000445912, ENST00000252034, 
ENST00000358929, ENST00000320492, 
ENST00000414324, ENST00000380562, 
ENST00000380575, ENST00000380584, 
ENST00000458204, ENST00000357036, 
ENST00000429192, ENST00000380553, 
ENST00000380576, ENST00000320399, 
ENST00000466878, 		ENST00000311506, 
Fusion gene scores* DoF score9 X 7 X 4=2527 X 7 X 5=245
# samples 98
** MAII scorelog2(9/252*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/245*10)=-1.61470984411521
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ELN [Title/Abstract] AND METTL2A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointELN(73442599)-METTL2A(60517978), # samples:2
Anticipated loss of major functional domain due to fusion event.ELN-METTL2A seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ELN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across METTL2A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AO-A0J3-01AELNchr7

73442599

+METTL2Achr17

60517978

+
ChimerDB4BRCATCGA-AO-A0J3ELNchr7

73442599

+METTL2Achr17

60525061

+
ChimerDB4BRCATCGA-AO-A0J3-01AELNchr7

73442599

+METTL2Achr17

60517978

+


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Fusion Gene ORF analysis for ELN-METTL2A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000445912ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000252034ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000358929ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000320492ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000414324ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000380562ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000380575ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000380584ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000458204ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000357036ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000429192ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000380553ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000380576ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
Frame-shiftENST00000320399ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
intron-3CDSENST00000466878ENST00000311506ELNchr7

73442599

+METTL2Achr17

60517978

+
In-frameENST00000445912ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000252034ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000358929ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000320492ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000414324ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000380562ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000380575ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000380584ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000458204ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000357036ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000429192ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000380553ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000380576ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
In-frameENST00000320399ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+
intron-3CDSENST00000466878ENST00000311506ELNchr7

73442599

+METTL2Achr17

60525061

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000445912ELNchr773442599+ENST00000311506METTL2Achr1760525061+20664813871129
ENST00000252034ELNchr773442599+ENST00000311506METTL2Achr1760525061+20664813871129
ENST00000358929ELNchr773442599+ENST00000311506METTL2Achr1760525061+175817314091086107
ENST00000320492ELNchr773442599+ENST00000311506METTL2Achr1760525061+174916414001077107
ENST00000414324ELNchr773442599+ENST00000311506METTL2Achr1760525061+172614113771054107
ENST00000380562ELNchr773442599+ENST00000311506METTL2Achr1760525061+171412913651042107
ENST00000380575ELNchr773442599+ENST00000311506METTL2Achr1760525061+169811313491026107
ENST00000380584ELNchr773442599+ENST00000311506METTL2Achr1760525061+169711213481025107
ENST00000458204ELNchr773442599+ENST00000311506METTL2Achr1760525061+169210713431020107
ENST00000357036ELNchr773442599+ENST00000311506METTL2Achr1760525061+168510013361013107
ENST00000429192ELNchr773442599+ENST00000311506METTL2Achr1760525061+16829713331010107
ENST00000380553ELNchr773442599+ENST00000311506METTL2Achr1760525061+16809513311008107
ENST00000380576ELNchr773442599+ENST00000311506METTL2Achr1760525061+16809513311008107
ENST00000320399ELNchr773442599+ENST00000311506METTL2Achr1760525061+1667821318995107

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000445912ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.85534370.14465633
ENST00000252034ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.85534370.14465633
ENST00000358929ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.68477380.3152262
ENST00000320492ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.64276570.35723424
ENST00000414324ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.496613440.50338656
ENST00000380562ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.5505270.44947302
ENST00000380575ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.297558750.7024412
ENST00000380584ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.332639660.66736037
ENST00000458204ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.484890130.51510984
ENST00000357036ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.445489170.55451083
ENST00000429192ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.335494160.66450584
ENST00000380553ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.37876720.6212328
ENST00000380576ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.37876720.6212328
ENST00000320399ENST00000311506ELNchr773442599+METTL2Achr1760525061+0.313921180.6860788

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Fusion Genomic Features for ELN-METTL2A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ELNchr773442599+METTL2Achr1760525061+0.91078140.08921862
ELNchr773442599+METTL2Achr1760517977+0.0001149310.9998851
ELNchr773442599+METTL2Achr1760525061+0.91078140.08921862
ELNchr773442599+METTL2Achr1760517977+0.0001149310.9998851

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ELN-METTL2A


check button Go to

FGviewer for the breakpoints of chr7:73442599-chr17:60525061

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.METTL2A

Q96IZ6

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). {ECO:0000269|PubMed:28655767}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneELNchr7:73442599chr17:60525061ENST00000252034+133236_74227.333333333333332725.0Compositional biasNote=Ala-rich
HgeneELNchr7:73442599chr17:60525061ENST00000252034+13397_10227.333333333333332725.0Compositional biasNote=Poly-Ala
HgeneELNchr7:73442599chr17:60525061ENST00000320399+133236_74227.333333333333332758.0Compositional biasNote=Ala-rich
HgeneELNchr7:73442599chr17:60525061ENST00000320399+13397_10227.333333333333332758.0Compositional biasNote=Poly-Ala
HgeneELNchr7:73442599chr17:60525061ENST00000357036+132236_74227.333333333333332712.0Compositional biasNote=Ala-rich
HgeneELNchr7:73442599chr17:60525061ENST00000357036+13297_10227.333333333333332712.0Compositional biasNote=Poly-Ala
HgeneELNchr7:73442599chr17:60525061ENST00000380553+125236_74227.333333333333332571.0Compositional biasNote=Ala-rich
HgeneELNchr7:73442599chr17:60525061ENST00000380553+12597_10227.333333333333332571.0Compositional biasNote=Poly-Ala
HgeneELNchr7:73442599chr17:60525061ENST00000380562+133236_74227.333333333333332731.0Compositional biasNote=Ala-rich
HgeneELNchr7:73442599chr17:60525061ENST00000380562+13397_10227.333333333333332731.0Compositional biasNote=Poly-Ala
HgeneELNchr7:73442599chr17:60525061ENST00000380575+130236_74227.333333333333332678.0Compositional biasNote=Ala-rich
HgeneELNchr7:73442599chr17:60525061ENST00000380575+13097_10227.333333333333332678.0Compositional biasNote=Poly-Ala
HgeneELNchr7:73442599chr17:60525061ENST00000380576+132236_74227.333333333333332706.0Compositional biasNote=Ala-rich
HgeneELNchr7:73442599chr17:60525061ENST00000380576+13297_10227.333333333333332706.0Compositional biasNote=Poly-Ala
HgeneELNchr7:73442599chr17:60525061ENST00000380584+129236_74227.333333333333332659.0Compositional biasNote=Ala-rich
HgeneELNchr7:73442599chr17:60525061ENST00000380584+12997_10227.333333333333332659.0Compositional biasNote=Poly-Ala
HgeneELNchr7:73442599chr17:60525061ENST00000429192+131236_74227.333333333333332693.0Compositional biasNote=Ala-rich
HgeneELNchr7:73442599chr17:60525061ENST00000429192+13197_10227.333333333333332693.0Compositional biasNote=Poly-Ala


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Fusion Gene Sequence for ELN-METTL2A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000445912_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=2066nt_BP=481nt
CCTCCCTTCTGCTTCCTCTCCCGAGGGCTGTCCTGGCAGAGGCCCCCCTCGCTCTTTCTGGCGGGAACAGGGCCAGCAGCGAAAGAACAG
TCGCAGAGGGAAAGCGGGAAAGAGATGGGGGAAAGTGTGTGTGTGTGAGTGTGTGCTTGTGTGCATGTGTGTGCGTGTGTGTGTCAAGGA
AAAAAGCTCGCAGTCCAGCAGCCCGGGCCTGGGAGGCTTGTGAGCCGGGCCTTTCGTAATTGTCCCCTCCCCGCGGCCCCCTCCCCCAGG
CCTCCCCCCTCTCCCGCCCTCCCGCCCGCCCTCTCTCCCTCCCTCTTTCCCTCACAGCCGACGAGGCAACAATTAGGCTTTGGGGATAAA
ACGAGGTGCGGAGAGCGGGCTGGGGCATTTCTCCCCGAGATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTG
CTGTCCATCCTCCACCCCTCTCGGCCTGGAGGTCAGTGTCTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTC
ACACAAGAGGAACTGGACACGCTTTTCACCACTGCTGGACTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGA
AAGCAACTGACAATGTACCGGGTTTGGATTCAGTGCAAATACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAAC
ACGATGCAAGCCCATTGTGTTTCCGGGCTTTTTTAAAAAAAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGG
AGGCTGAGGCGGGGAGGATCCATTGAGCCCAGCAGTCCAACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATA
AAAAATATAAATGAGGTCTCGTTGATGTTGGACAATTCAAGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGAT
TCTAACAATTATGCTTCATATTTGTGAAGTCCTTTAAAACATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTT
GTAACTAATAACTGAAATTTTATTCAAAGGAATTGTAAACCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGT
GTTTTTTGACTGTAATTGCGTTAAATCTTTTGAGAATGTAAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGG
CTTATTAAGTTGTAGGGGAAGCAAGCTGGGAAGAATCAGATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAAT
GTGGTGTTCTTGTTAAGTAATTGATCGTGGTCTTCGCTTTAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTT
TGGGAGGCCAAGGCGGGCGGATCAGCTGAGGTCAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAA
AAAATTAGCTGAGTGTGTTGGTGGGTGCCTGTAATCCAGCTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGT
TGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTT
AGTTCCATGGAATTTTAAGCATTGTTCCCCCTCTAACCTGTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTA
ATCCCAACACTTTGGGAGGCTGAGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCAC
TAAAAATACCAAAAAAATTAGCTGGGCATGGTGGCACACACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAAT

>In-frame_ENST00000445912_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=129AA_start in transcript=387_stop in transcript=1
MPQPALRTSFYPQSLIVASSAVRERGRERGRAGGRERGEAWGRGPRGGDNYERPGSQASQARAAGLRAFFLDTHTHTHAHKHTLTHTHFP

--------------------------------------------------------------
>In-frame_ENST00000252034_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=2066nt_BP=481nt
CCTCCCTTCTGCTTCCTCTCCCGAGGGCTGTCCTGGCAGAGGCCCCCCTCGCTCTTTCTGGCGGGAACAGGGCCAGCAGCGAAAGAACAG
TCGCAGAGGGAAAGCGGGAAAGAGATGGGGGAAAGTGTGTGTGTGTGAGTGTGTGCTTGTGTGCATGTGTGTGCGTGTGTGTGTCAAGGA
AAAAAGCTCGCAGTCCAGCAGCCCGGGCCTGGGAGGCTTGTGAGCCGGGCCTTTCGTAATTGTCCCCTCCCCGCGGCCCCCTCCCCCAGG
CCTCCCCCCTCTCCCGCCCTCCCGCCCGCCCTCTCTCCCTCCCTCTTTCCCTCACAGCCGACGAGGCAACAATTAGGCTTTGGGGATAAA
ACGAGGTGCGGAGAGCGGGCTGGGGCATTTCTCCCCGAGATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTG
CTGTCCATCCTCCACCCCTCTCGGCCTGGAGGTCAGTGTCTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTC
ACACAAGAGGAACTGGACACGCTTTTCACCACTGCTGGACTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGA
AAGCAACTGACAATGTACCGGGTTTGGATTCAGTGCAAATACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAAC
ACGATGCAAGCCCATTGTGTTTCCGGGCTTTTTTAAAAAAAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGG
AGGCTGAGGCGGGGAGGATCCATTGAGCCCAGCAGTCCAACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATA
AAAAATATAAATGAGGTCTCGTTGATGTTGGACAATTCAAGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGAT
TCTAACAATTATGCTTCATATTTGTGAAGTCCTTTAAAACATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTT
GTAACTAATAACTGAAATTTTATTCAAAGGAATTGTAAACCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGT
GTTTTTTGACTGTAATTGCGTTAAATCTTTTGAGAATGTAAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGG
CTTATTAAGTTGTAGGGGAAGCAAGCTGGGAAGAATCAGATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAAT
GTGGTGTTCTTGTTAAGTAATTGATCGTGGTCTTCGCTTTAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTT
TGGGAGGCCAAGGCGGGCGGATCAGCTGAGGTCAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAA
AAAATTAGCTGAGTGTGTTGGTGGGTGCCTGTAATCCAGCTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGT
TGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTT
AGTTCCATGGAATTTTAAGCATTGTTCCCCCTCTAACCTGTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTA
ATCCCAACACTTTGGGAGGCTGAGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCAC
TAAAAATACCAAAAAAATTAGCTGGGCATGGTGGCACACACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAAT

>In-frame_ENST00000252034_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=129AA_start in transcript=387_stop in transcript=1
MPQPALRTSFYPQSLIVASSAVRERGRERGRAGGRERGEAWGRGPRGGDNYERPGSQASQARAAGLRAFFLDTHTHTHAHKHTLTHTHFP

--------------------------------------------------------------
>In-frame_ENST00000358929_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1758nt_BP=173nt
CTCCCTCTTTCCCTCACAGCCGACGAGGCAACAATTAGGCTTTGGGGATAAAACGAGGTGCGGAGAGCGGGCTGGGGCATTTCTCCCCGA
GATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTGCTGTCCATCCTCCACCCCTCTCGGCCTGGAGGTCAGTG
TCTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTCACACAAGAGGAACTGGACACGCTTTTCACCACTGCTGG
ACTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGAAAGCAACTGACAATGTACCGGGTTTGGATTCAGTGCAA
ATACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAACACGATGCAAGCCCATTGTGTTTCCGGGCTTTTTTAAAA
AAAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGGAGGCTGAGGCGGGGAGGATCCATTGAGCCCAGCAGTCC
AACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATAAAAAATATAAATGAGGTCTCGTTGATGTTGGACAATTC
AAGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGATTCTAACAATTATGCTTCATATTTGTGAAGTCCTTTAAA
ACATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTTGTAACTAATAACTGAAATTTTATTCAAAGGAATTGTAA
ACCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGTGTTTTTTGACTGTAATTGCGTTAAATCTTTTGAGAATG
TAAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGGCTTATTAAGTTGTAGGGGAAGCAAGCTGGGAAGAATCA
GATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAATGTGGTGTTCTTGTTAAGTAATTGATCGTGGTCTTCGCT
TTAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCAGCTGAGGTCAGGAG
TTGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAAAAAATTAGCTGAGTGTGTTGGTGGGTGCCTGTAATCCA
GCTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTG
GGCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTTAGTTCCATGGAATTTTAAGCATTGTTCCCCCTCTAACC
TGTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGAGGCAGGCGGATCACG
AGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCACTAAAAATACCAAAAAAATTAGCTGGGCATGGTGGCACA
CACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGTTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCAAG

>In-frame_ENST00000358929_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1409_stop in transcript=1086
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------
>In-frame_ENST00000320492_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1749nt_BP=164nt
TCCCTCACAGCCGACGAGGCAACAATTAGGCTTTGGGGATAAAACGAGGTGCGGAGAGCGGGCTGGGGCATTTCTCCCCGAGATGGCGGG
TCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTGCTGTCCATCCTCCACCCCTCTCGGCCTGGAGGTCAGTGTCTATCTGG
AAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTCACACAAGAGGAACTGGACACGCTTTTCACCACTGCTGGACTGGAAAA
AGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGAAAGCAACTGACAATGTACCGGGTTTGGATTCAGTGCAAATACTGCAA
GCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAACACGATGCAAGCCCATTGTGTTTCCGGGCTTTTTTAAAAAAAAAATTG
TAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGGAGGCTGAGGCGGGGAGGATCCATTGAGCCCAGCAGTCCAACCTGGGC
AAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATAAAAAATATAAATGAGGTCTCGTTGATGTTGGACAATTCAAGAATTCA
GACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGATTCTAACAATTATGCTTCATATTTGTGAAGTCCTTTAAAACATAATTT
TCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTTGTAACTAATAACTGAAATTTTATTCAAAGGAATTGTAAACCTTAAAC
CACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGTGTTTTTTGACTGTAATTGCGTTAAATCTTTTGAGAATGTAAATGCCG
GGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGGCTTATTAAGTTGTAGGGGAAGCAAGCTGGGAAGAATCAGATCAGATA
TTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAATGTGGTGTTCTTGTTAAGTAATTGATCGTGGTCTTCGCTTTAATCTTA
GTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCAGCTGAGGTCAGGAGTTGGAGACC
AGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAAAAAATTAGCTGAGTGTGTTGGTGGGTGCCTGTAATCCAGCTACTTGG
GAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAA
GCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTTAGTTCCATGGAATTTTAAGCATTGTTCCCCCTCTAACCTGTGTCTAA
AGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGAGGCAGGCGGATCACGAGGTCAGGA
GATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCACTAAAAATACCAAAAAAATTAGCTGGGCATGGTGGCACACACCTGTAG
TCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGTTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCAAGATCATGTCA

>In-frame_ENST00000320492_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1400_stop in transcript=1077
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------
>In-frame_ENST00000414324_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1726nt_BP=141nt
AATTAGGCTTTGGGGATAAAACGAGGTGCGGAGAGCGGGCTGGGGCATTTCTCCCCGAGATGGCGGGTCTGACGGCGGCGGCCCCGCGGC
CCGGAGTCCTCCTGCTCCTGCTGTCCATCCTCCACCCCTCTCGGCCTGGAGGTCAGTGTCTATCTGGAAATTTCTACGTGAGAGGTGATG
GAACCAGAGTTTACTTCTTCACACAAGAGGAACTGGACACGCTTTTCACCACTGCTGGACTGGAAAAAGTTCAGAACCTGGTGGATCGCC
GACTGCAGGTGAACCGAGGAAAGCAACTGACAATGTACCGGGTTTGGATTCAGTGCAAATACTGCAAGCCCCTTCTGTCCAGCACCAGCT
GAGAGGCACCTGCTGCCAACACGATGCAAGCCCATTGTGTTTCCGGGCTTTTTTAAAAAAAAAATTGTAGCACTGGGCGTGGTGCATGCC
TGTAATCCCAGCCACTCAGGAGGCTGAGGCGGGGAGGATCCATTGAGCCCAGCAGTCCAACCTGGGCAAAATAGTGAGAGACCCTGTATC
TGAAAGTAATAATAAAAATAAAAAATATAAATGAGGTCTCGTTGATGTTGGACAATTCAAGAATTCAGACTTGAACCTTAAACCTAGGAA
AAGTTACTTTGTATCAGGATTCTAACAATTATGCTTCATATTTGTGAAGTCCTTTAAAACATAATTTTCTCAAGTTCTTTCTTTGAGATC
TCAATCTGTCTTAGCATTTTGTAACTAATAACTGAAATTTTATTCAAAGGAATTGTAAACCTTAAACCACCAATTTATTTCCATGTGAAA
AAGTGTTACATATGACAAGTGTTTTTTGACTGTAATTGCGTTAAATCTTTTGAGAATGTAAATGCCGGGCTAGGCAATTGCAGTTAATAC
ATACAGAGGTTAGTGAAGGGCTTATTAAGTTGTAGGGGAAGCAAGCTGGGAAGAATCAGATCAGATATTTTCCTGACAAAAAAAAATGAC
CCTACAGAGAGCATCAAAATGTGGTGTTCTTGTTAAGTAATTGATCGTGGTCTTCGCTTTAATCTTAGTTCCGCCAGGCACGGTGGCTCA
CACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCAGCTGAGGTCAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAACC
CCGTCTCTACTAAAGATAAAAAAATTAGCTGAGTGTGTTGGTGGGTGCCTGTAATCCAGCTACTTGGGAGACTGAGGCAGGAGAATTGCT
TGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCAAGACTCTGTCTCAAAAAAAT
AAAAATAAAAAAAAAATCTTAGTTCCATGGAATTTTAAGCATTGTTCCCCCTCTAACCTGTGTCTAAAGAATTAAAAGAATTTGGCCGGG
TGCGGCAGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGAGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACA
CGGTGAAACCTCGTCTCCACTAAAAATACCAAAAAAATTAGCTGGGCATGGTGGCACACACCTGTAGTCCCCTGTAGTCCCAGCTACTCG
GGAGGCTGAGGCAGGAGAATCGTTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCAAGATCATGTCACTGCATTCCAGCCTGGGCAACAG

>In-frame_ENST00000414324_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1377_stop in transcript=1054
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------
>In-frame_ENST00000380562_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1714nt_BP=129nt
GGGATAAAACGAGGTGCGGAGAGCGGGCTGGGGCATTTCTCCCCGAGATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCC
TGCTCCTGCTGTCCATCCTCCACCCCTCTCGGCCTGGAGGTCAGTGTCTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTT
ACTTCTTCACACAAGAGGAACTGGACACGCTTTTCACCACTGCTGGACTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGA
ACCGAGGAAAGCAACTGACAATGTACCGGGTTTGGATTCAGTGCAAATACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTG
CTGCCAACACGATGCAAGCCCATTGTGTTTCCGGGCTTTTTTAAAAAAAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGC
CACTCAGGAGGCTGAGGCGGGGAGGATCCATTGAGCCCAGCAGTCCAACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAA
TAAAAATAAAAAATATAAATGAGGTCTCGTTGATGTTGGACAATTCAAGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGT
ATCAGGATTCTAACAATTATGCTTCATATTTGTGAAGTCCTTTAAAACATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTT
AGCATTTTGTAACTAATAACTGAAATTTTATTCAAAGGAATTGTAAACCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATA
TGACAAGTGTTTTTTGACTGTAATTGCGTTAAATCTTTTGAGAATGTAAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTA
GTGAAGGGCTTATTAAGTTGTAGGGGAAGCAAGCTGGGAAGAATCAGATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGC
ATCAAAATGTGGTGTTCTTGTTAAGTAATTGATCGTGGTCTTCGCTTTAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCC
CAGCACTTTGGGAGGCCAAGGCGGGCGGATCAGCTGAGGTCAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTA
AAGATAAAAAAATTAGCTGAGTGTGTTGGTGGGTGCCTGTAATCCAGCTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAG
GCAGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAA
AAAATCTTAGTTCCATGGAATTTTAAGCATTGTTCCCCCTCTAACCTGTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCA
TGCCTGTAATCCCAACACTTTGGGAGGCTGAGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTC
GTCTCCACTAAAAATACCAAAAAAATTAGCTGGGCATGGTGGCACACACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGC
AGGAGAATCGTTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCAAGATCATGTCACTGCATTCCAGCCTGGGCAACAGAGGAAGACTCCG

>In-frame_ENST00000380562_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1365_stop in transcript=1042
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------
>In-frame_ENST00000380575_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1698nt_BP=113nt
CGGAGAGCGGGCTGGGGCATTTCTCCCCGAGATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTGCTGTCCAT
CCTCCACCCCTCTCGGCCTGGAGGTCAGTGTCTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTCACACAAGA
GGAACTGGACACGCTTTTCACCACTGCTGGACTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGAAAGCAACT
GACAATGTACCGGGTTTGGATTCAGTGCAAATACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAACACGATGCA
AGCCCATTGTGTTTCCGGGCTTTTTTAAAAAAAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGGAGGCTGAG
GCGGGGAGGATCCATTGAGCCCAGCAGTCCAACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATAAAAAATAT
AAATGAGGTCTCGTTGATGTTGGACAATTCAAGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGATTCTAACAA
TTATGCTTCATATTTGTGAAGTCCTTTAAAACATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTTGTAACTAA
TAACTGAAATTTTATTCAAAGGAATTGTAAACCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGTGTTTTTTG
ACTGTAATTGCGTTAAATCTTTTGAGAATGTAAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGGCTTATTAA
GTTGTAGGGGAAGCAAGCTGGGAAGAATCAGATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAATGTGGTGTT
CTTGTTAAGTAATTGATCGTGGTCTTCGCTTTAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGC
CAAGGCGGGCGGATCAGCTGAGGTCAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAAAAAATTAG
CTGAGTGTGTTGGTGGGTGCCTGTAATCCAGCTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGA
GCTGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTTAGTTCCAT
GGAATTTTAAGCATTGTTCCCCCTCTAACCTGTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTAATCCCAAC
ACTTTGGGAGGCTGAGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCACTAAAAATA
CCAAAAAAATTAGCTGGGCATGGTGGCACACACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGTTTGAA

>In-frame_ENST00000380575_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1349_stop in transcript=1026
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------
>In-frame_ENST00000380584_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1697nt_BP=112nt
GGAGAGCGGGCTGGGGCATTTCTCCCCGAGATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTGCTGTCCATC
CTCCACCCCTCTCGGCCTGGAGGTCAGTGTCTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTCACACAAGAG
GAACTGGACACGCTTTTCACCACTGCTGGACTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGAAAGCAACTG
ACAATGTACCGGGTTTGGATTCAGTGCAAATACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAACACGATGCAA
GCCCATTGTGTTTCCGGGCTTTTTTAAAAAAAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGGAGGCTGAGG
CGGGGAGGATCCATTGAGCCCAGCAGTCCAACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATAAAAAATATA
AATGAGGTCTCGTTGATGTTGGACAATTCAAGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGATTCTAACAAT
TATGCTTCATATTTGTGAAGTCCTTTAAAACATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTTGTAACTAAT
AACTGAAATTTTATTCAAAGGAATTGTAAACCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGTGTTTTTTGA
CTGTAATTGCGTTAAATCTTTTGAGAATGTAAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGGCTTATTAAG
TTGTAGGGGAAGCAAGCTGGGAAGAATCAGATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAATGTGGTGTTC
TTGTTAAGTAATTGATCGTGGTCTTCGCTTTAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCC
AAGGCGGGCGGATCAGCTGAGGTCAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAAAAAATTAGC
TGAGTGTGTTGGTGGGTGCCTGTAATCCAGCTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAG
CTGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTTAGTTCCATG
GAATTTTAAGCATTGTTCCCCCTCTAACCTGTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTAATCCCAACA
CTTTGGGAGGCTGAGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCACTAAAAATAC
CAAAAAAATTAGCTGGGCATGGTGGCACACACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGTTTGAAC

>In-frame_ENST00000380584_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1348_stop in transcript=1025
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------
>In-frame_ENST00000458204_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1692nt_BP=107nt
GCGGGCTGGGGCATTTCTCCCCGAGATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTGCTGTCCATCCTCCA
CCCCTCTCGGCCTGGAGGTCAGTGTCTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTCACACAAGAGGAACT
GGACACGCTTTTCACCACTGCTGGACTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGAAAGCAACTGACAAT
GTACCGGGTTTGGATTCAGTGCAAATACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAACACGATGCAAGCCCA
TTGTGTTTCCGGGCTTTTTTAAAAAAAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGGAGGCTGAGGCGGGG
AGGATCCATTGAGCCCAGCAGTCCAACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATAAAAAATATAAATGA
GGTCTCGTTGATGTTGGACAATTCAAGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGATTCTAACAATTATGC
TTCATATTTGTGAAGTCCTTTAAAACATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTTGTAACTAATAACTG
AAATTTTATTCAAAGGAATTGTAAACCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGTGTTTTTTGACTGTA
ATTGCGTTAAATCTTTTGAGAATGTAAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGGCTTATTAAGTTGTA
GGGGAAGCAAGCTGGGAAGAATCAGATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAATGTGGTGTTCTTGTT
AAGTAATTGATCGTGGTCTTCGCTTTAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGC
GGGCGGATCAGCTGAGGTCAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAAAAAATTAGCTGAGT
GTGTTGGTGGGTGCCTGTAATCCAGCTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAG
ATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTTAGTTCCATGGAATT
TTAAGCATTGTTCCCCCTCTAACCTGTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTAATCCCAACACTTTG
GGAGGCTGAGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCACTAAAAATACCAAAA
AAATTAGCTGGGCATGGTGGCACACACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGTTTGAACCTGGG

>In-frame_ENST00000458204_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1343_stop in transcript=1020
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------
>In-frame_ENST00000357036_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1685nt_BP=100nt
GGGGCATTTCTCCCCGAGATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTGCTGTCCATCCTCCACCCCTCT
CGGCCTGGAGGTCAGTGTCTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTCACACAAGAGGAACTGGACACG
CTTTTCACCACTGCTGGACTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGAAAGCAACTGACAATGTACCGG
GTTTGGATTCAGTGCAAATACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAACACGATGCAAGCCCATTGTGTT
TCCGGGCTTTTTTAAAAAAAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGGAGGCTGAGGCGGGGAGGATCC
ATTGAGCCCAGCAGTCCAACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATAAAAAATATAAATGAGGTCTCG
TTGATGTTGGACAATTCAAGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGATTCTAACAATTATGCTTCATAT
TTGTGAAGTCCTTTAAAACATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTTGTAACTAATAACTGAAATTTT
ATTCAAAGGAATTGTAAACCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGTGTTTTTTGACTGTAATTGCGT
TAAATCTTTTGAGAATGTAAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGGCTTATTAAGTTGTAGGGGAAG
CAAGCTGGGAAGAATCAGATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAATGTGGTGTTCTTGTTAAGTAAT
TGATCGTGGTCTTCGCTTTAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGA
TCAGCTGAGGTCAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAAAAAATTAGCTGAGTGTGTTGG
TGGGTGCCTGTAATCCAGCTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGTGC
CACTGCACTCCAGCCTGGGCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTTAGTTCCATGGAATTTTAAGCA
TTGTTCCCCCTCTAACCTGTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTAATCCCAACACTTTGGGAGGCT
GAGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCACTAAAAATACCAAAAAAATTAG
CTGGGCATGGTGGCACACACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGTTTGAACCTGGGAGGTGGA

>In-frame_ENST00000357036_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1336_stop in transcript=1013
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------
>In-frame_ENST00000429192_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1682nt_BP=97nt
GCATTTCTCCCCGAGATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTGCTGTCCATCCTCCACCCCTCTCGG
CCTGGAGGTCAGTGTCTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTCACACAAGAGGAACTGGACACGCTT
TTCACCACTGCTGGACTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGAAAGCAACTGACAATGTACCGGGTT
TGGATTCAGTGCAAATACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAACACGATGCAAGCCCATTGTGTTTCC
GGGCTTTTTTAAAAAAAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGGAGGCTGAGGCGGGGAGGATCCATT
GAGCCCAGCAGTCCAACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATAAAAAATATAAATGAGGTCTCGTTG
ATGTTGGACAATTCAAGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGATTCTAACAATTATGCTTCATATTTG
TGAAGTCCTTTAAAACATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTTGTAACTAATAACTGAAATTTTATT
CAAAGGAATTGTAAACCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGTGTTTTTTGACTGTAATTGCGTTAA
ATCTTTTGAGAATGTAAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGGCTTATTAAGTTGTAGGGGAAGCAA
GCTGGGAAGAATCAGATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAATGTGGTGTTCTTGTTAAGTAATTGA
TCGTGGTCTTCGCTTTAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCA
GCTGAGGTCAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAAAAAATTAGCTGAGTGTGTTGGTGG
GTGCCTGTAATCCAGCTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCAC
TGCACTCCAGCCTGGGCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTTAGTTCCATGGAATTTTAAGCATTG
TTCCCCCTCTAACCTGTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGAG
GCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCACTAAAAATACCAAAAAAATTAGCTG
GGCATGGTGGCACACACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGTTTGAACCTGGGAGGTGGAGGT

>In-frame_ENST00000429192_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1333_stop in transcript=1010
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------
>In-frame_ENST00000380553_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1680nt_BP=95nt
ATTTCTCCCCGAGATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTGCTGTCCATCCTCCACCCCTCTCGGCC
TGGAGGTCAGTGTCTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTCACACAAGAGGAACTGGACACGCTTTT
CACCACTGCTGGACTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGAAAGCAACTGACAATGTACCGGGTTTG
GATTCAGTGCAAATACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAACACGATGCAAGCCCATTGTGTTTCCGG
GCTTTTTTAAAAAAAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGGAGGCTGAGGCGGGGAGGATCCATTGA
GCCCAGCAGTCCAACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATAAAAAATATAAATGAGGTCTCGTTGAT
GTTGGACAATTCAAGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGATTCTAACAATTATGCTTCATATTTGTG
AAGTCCTTTAAAACATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTTGTAACTAATAACTGAAATTTTATTCA
AAGGAATTGTAAACCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGTGTTTTTTGACTGTAATTGCGTTAAAT
CTTTTGAGAATGTAAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGGCTTATTAAGTTGTAGGGGAAGCAAGC
TGGGAAGAATCAGATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAATGTGGTGTTCTTGTTAAGTAATTGATC
GTGGTCTTCGCTTTAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCAGC
TGAGGTCAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAAAAAATTAGCTGAGTGTGTTGGTGGGT
GCCTGTAATCCAGCTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCACTG
CACTCCAGCCTGGGCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTTAGTTCCATGGAATTTTAAGCATTGTT
CCCCCTCTAACCTGTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGAGGC
AGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCACTAAAAATACCAAAAAAATTAGCTGGG
CATGGTGGCACACACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGTTTGAACCTGGGAGGTGGAGGTTG

>In-frame_ENST00000380553_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1331_stop in transcript=1008
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------
>In-frame_ENST00000380576_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1680nt_BP=95nt
ATTTCTCCCCGAGATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTGCTGTCCATCCTCCACCCCTCTCGGCC
TGGAGGTCAGTGTCTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTCACACAAGAGGAACTGGACACGCTTTT
CACCACTGCTGGACTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGAAAGCAACTGACAATGTACCGGGTTTG
GATTCAGTGCAAATACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAACACGATGCAAGCCCATTGTGTTTCCGG
GCTTTTTTAAAAAAAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGGAGGCTGAGGCGGGGAGGATCCATTGA
GCCCAGCAGTCCAACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATAAAAAATATAAATGAGGTCTCGTTGAT
GTTGGACAATTCAAGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGATTCTAACAATTATGCTTCATATTTGTG
AAGTCCTTTAAAACATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTTGTAACTAATAACTGAAATTTTATTCA
AAGGAATTGTAAACCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGTGTTTTTTGACTGTAATTGCGTTAAAT
CTTTTGAGAATGTAAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGGCTTATTAAGTTGTAGGGGAAGCAAGC
TGGGAAGAATCAGATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAATGTGGTGTTCTTGTTAAGTAATTGATC
GTGGTCTTCGCTTTAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCAGC
TGAGGTCAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAAAAAATTAGCTGAGTGTGTTGGTGGGT
GCCTGTAATCCAGCTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCACTG
CACTCCAGCCTGGGCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTTAGTTCCATGGAATTTTAAGCATTGTT
CCCCCTCTAACCTGTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGAGGC
AGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCACTAAAAATACCAAAAAAATTAGCTGGG
CATGGTGGCACACACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGTTTGAACCTGGGAGGTGGAGGTTG

>In-frame_ENST00000380576_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1331_stop in transcript=1008
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------
>In-frame_ENST00000320399_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(transcript)=1667nt_BP=82nt
ATGGCGGGTCTGACGGCGGCGGCCCCGCGGCCCGGAGTCCTCCTGCTCCTGCTGTCCATCCTCCACCCCTCTCGGCCTGGAGGTCAGTGT
CTATCTGGAAATTTCTACGTGAGAGGTGATGGAACCAGAGTTTACTTCTTCACACAAGAGGAACTGGACACGCTTTTCACCACTGCTGGA
CTGGAAAAAGTTCAGAACCTGGTGGATCGCCGACTGCAGGTGAACCGAGGAAAGCAACTGACAATGTACCGGGTTTGGATTCAGTGCAAA
TACTGCAAGCCCCTTCTGTCCAGCACCAGCTGAGAGGCACCTGCTGCCAACACGATGCAAGCCCATTGTGTTTCCGGGCTTTTTTAAAAA
AAAAATTGTAGCACTGGGCGTGGTGCATGCCTGTAATCCCAGCCACTCAGGAGGCTGAGGCGGGGAGGATCCATTGAGCCCAGCAGTCCA
ACCTGGGCAAAATAGTGAGAGACCCTGTATCTGAAAGTAATAATAAAAATAAAAAATATAAATGAGGTCTCGTTGATGTTGGACAATTCA
AGAATTCAGACTTGAACCTTAAACCTAGGAAAAGTTACTTTGTATCAGGATTCTAACAATTATGCTTCATATTTGTGAAGTCCTTTAAAA
CATAATTTTCTCAAGTTCTTTCTTTGAGATCTCAATCTGTCTTAGCATTTTGTAACTAATAACTGAAATTTTATTCAAAGGAATTGTAAA
CCTTAAACCACCAATTTATTTCCATGTGAAAAAGTGTTACATATGACAAGTGTTTTTTGACTGTAATTGCGTTAAATCTTTTGAGAATGT
AAATGCCGGGCTAGGCAATTGCAGTTAATACATACAGAGGTTAGTGAAGGGCTTATTAAGTTGTAGGGGAAGCAAGCTGGGAAGAATCAG
ATCAGATATTTTCCTGACAAAAAAAAATGACCCTACAGAGAGCATCAAAATGTGGTGTTCTTGTTAAGTAATTGATCGTGGTCTTCGCTT
TAATCTTAGTTCCGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCAGCTGAGGTCAGGAGT
TGGAGACCAGCGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAGATAAAAAAATTAGCTGAGTGTGTTGGTGGGTGCCTGTAATCCAG
CTACTTGGGAGACTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGG
GCAACAAAGCAAGACTCTGTCTCAAAAAAATAAAAATAAAAAAAAAATCTTAGTTCCATGGAATTTTAAGCATTGTTCCCCCTCTAACCT
GTGTCTAAAGAATTAAAAGAATTTGGCCGGGTGCGGCAGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGAGGCAGGCGGATCACGA
GGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCTCGTCTCCACTAAAAATACCAAAAAAATTAGCTGGGCATGGTGGCACAC
ACCTGTAGTCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGTTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCAAGA

>In-frame_ENST00000320399_ENST00000311506_TCGA-AO-A0J3_ELN_chr7_73442599_+_METTL2A_chr17_60525061_length(amino acids)=107AA_start in transcript=1318_stop in transcript=995
MELRFFFYFYFFETESCFVAQAGVQWHNLSSLQPLPPGFKQFSCLSLPSSWITGTHQHTQLIFLSLVETGFHHVGHAGLQLLTSADPPAL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ELN-METTL2A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ELN-METTL2A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ELN-METTL2A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneELNC0003499Supravalvular aortic stenosis7CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneELNC0010495Cutis Laxa2CTD_human;GENOMICS_ENGLAND
HgeneELNC0034069Pulmonary Fibrosis2CTD_human
HgeneELNC0268350Cutis Laxa, Autosomal Dominant2CTD_human;ORPHANET
HgeneELNC1305147Congenital supravalvular aortic stenosis2ORPHANET
HgeneELNC4721507Alveolitis, Fibrosing2CTD_human
HgeneELNC0019284Diaphragmatic Hernia1CTD_human
HgeneELNC0020538Hypertensive disease1CTD_human
HgeneELNC0024117Chronic Obstructive Airway Disease1CTD_human
HgeneELNC0026654Moyamoya Disease1GENOMICS_ENGLAND
HgeneELNC0034067Pulmonary Emphysema1CTD_human
HgeneELNC0151744Myocardial Ischemia1CTD_human
HgeneELNC0221227Centriacinar Emphysema1CTD_human
HgeneELNC0238288Muscular Dystrophy, Facioscapulohumeral1CTD_human
HgeneELNC0264393Panacinar Emphysema1CTD_human
HgeneELNC1527303Chronic Airflow Obstruction1CTD_human
HgeneELNC1862932ANEURYSM, INTRACRANIAL BERRY, 1 (disorder)1GENOMICS_ENGLAND
HgeneELNC2350878Focal Emphysema1CTD_human
HgeneELNC3276539CUTIS LAXA, AUTOSOMAL DOMINANT 11GENOMICS_ENGLAND
HgeneELNC4317009Diverticular Diseases1CTD_human
HgeneELNC4505353Diverticular Bleeding1CTD_human
HgeneELNC4707243Familial thoracic aortic aneurysm and aortic dissection1GENOMICS_ENGLAND;ORPHANET