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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ENSA-RASEF (FusionGDB2 ID:26640)

Fusion Gene Summary for ENSA-RASEF

check button Fusion gene summary
Fusion gene informationFusion gene name: ENSA-RASEF
Fusion gene ID: 26640
HgeneTgene
Gene symbol

ENSA

RASEF

Gene ID

2029

158158

Gene nameendosulfine alphaRAS and EF-hand domain containing
SynonymsARPP-19eRAB45
Cytomap

1q21.3

9q21.32

Type of geneprotein-codingprotein-coding
Descriptionalpha-endosulfineras and EF-hand domain-containing proteinras-related protein Rab-45
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000369016, ENST00000369014, 
ENST00000369009, ENST00000339643, 
ENST00000271690, ENST00000356527, 
ENST00000503345, ENST00000503241, 
ENST00000362052, ENST00000361532, 
ENST00000361631, ENST00000513281, 
ENST00000354702, 		ENST00000376447, 
ENST00000340717, 
Fusion gene scores* DoF score13 X 11 X 6=8587 X 6 X 4=168
# samples 177
** MAII scorelog2(17/858*10)=-2.33544290136184
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/168*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ENSA [Title/Abstract] AND RASEF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointENSA(150598118)-RASEF(85640837), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneENSA

GO:0050796

regulation of insulin secretion

9653196


check buttonFusion gene breakpoints across ENSA (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across RASEF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ADB237062ENSAchr1

150598118

-RASEFchr9

85640837

-


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Fusion Gene ORF analysis for ENSA-RASEF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000369016ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
5CDS-intronENST00000369016ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
In-frameENST00000369014ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
5CDS-intronENST00000369014ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
In-frameENST00000369009ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
5CDS-intronENST00000369009ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
In-frameENST00000339643ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
5CDS-intronENST00000339643ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-3CDSENST00000271690ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-intronENST00000271690ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-3CDSENST00000356527ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-intronENST00000356527ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-3CDSENST00000503345ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-intronENST00000503345ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-3CDSENST00000503241ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-intronENST00000503241ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-3CDSENST00000362052ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-intronENST00000362052ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
In-frameENST00000361532ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
5CDS-intronENST00000361532ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
In-frameENST00000361631ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
5CDS-intronENST00000361631ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-3CDSENST00000513281ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-intronENST00000513281ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-3CDSENST00000354702ENST00000376447ENSAchr1

150598118

-RASEFchr9

85640837

-
intron-intronENST00000354702ENST00000340717ENSAchr1

150598118

-RASEFchr9

85640837

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000369016ENSAchr1150598118-ENST00000376447RASEFchr985640837-5378494182285755
ENST00000369014ENSAchr1150598118-ENST00000376447RASEFchr985640837-5360476482267739
ENST00000369009ENSAchr1150598118-ENST00000376447RASEFchr985640837-5429545482336762
ENST00000339643ENSAchr1150598118-ENST00000376447RASEFchr985640837-5388504282295755
ENST00000361532ENSAchr1150598118-ENST00000376447RASEFchr985640837-5257373352164709
ENST00000361631ENSAchr1150598118-ENST00000376447RASEFchr985640837-5293409232200725

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000369016ENST00000376447ENSAchr1150598118-RASEFchr985640837-9.16E-050.99990845
ENST00000369014ENST00000376447ENSAchr1150598118-RASEFchr985640837-0.0002050580.9997949
ENST00000369009ENST00000376447ENSAchr1150598118-RASEFchr985640837-0.0002780030.99972194
ENST00000339643ENST00000376447ENSAchr1150598118-RASEFchr985640837-9.23E-050.99990773
ENST00000361532ENST00000376447ENSAchr1150598118-RASEFchr985640837-0.0001992590.99980074
ENST00000361631ENST00000376447ENSAchr1150598118-RASEFchr985640837-0.0003285290.99967146

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Fusion Genomic Features for ENSA-RASEF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ENSA-RASEF


check button Go to

FGviewer for the breakpoints of chr1:150598118-chr9:85640837

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRASEFchr1:150598118chr9:85640837ENST000003407170221_320190.0Calcium binding1
TgeneRASEFchr1:150598118chr9:85640837ENST000003407170255_660190.0Calcium binding2
TgeneRASEFchr1:150598118chr9:85640837ENST0000034071702175_3560190.0Coiled coilOntology_term=ECO:0000255
TgeneRASEFchr1:150598118chr9:85640837ENST00000376447017175_356143.66666666666666741.0Coiled coilOntology_term=ECO:0000255
TgeneRASEFchr1:150598118chr9:85640837ENST000003407170242_770190.0DomainEF-hand 2
TgeneRASEFchr1:150598118chr9:85640837ENST00000340717028_420190.0DomainEF-hand 1
TgeneRASEFchr1:150598118chr9:85640837ENST0000034071702551_5560190.0Nucleotide bindingGTP
TgeneRASEFchr1:150598118chr9:85640837ENST0000034071702654_6570190.0Nucleotide bindingGTP
TgeneRASEFchr1:150598118chr9:85640837ENST0000034071702691_6920190.0Nucleotide bindingGTP
TgeneRASEFchr1:150598118chr9:85640837ENST00000376447017551_556143.66666666666666741.0Nucleotide bindingGTP
TgeneRASEFchr1:150598118chr9:85640837ENST00000376447017654_657143.66666666666666741.0Nucleotide bindingGTP
TgeneRASEFchr1:150598118chr9:85640837ENST00000376447017691_692143.66666666666666741.0Nucleotide bindingGTP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRASEFchr1:150598118chr9:85640837ENST0000037644701721_32143.66666666666666741.0Calcium binding1
TgeneRASEFchr1:150598118chr9:85640837ENST0000037644701755_66143.66666666666666741.0Calcium binding2
TgeneRASEFchr1:150598118chr9:85640837ENST0000037644701742_77143.66666666666666741.0DomainEF-hand 2
TgeneRASEFchr1:150598118chr9:85640837ENST000003764470178_42143.66666666666666741.0DomainEF-hand 1


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Fusion Gene Sequence for ENSA-RASEF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000369016_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(transcript)=5378nt_BP=494nt
CCGAAGCAGCAGCGCAGGTTGTCCCCGTTTCCCCTCCCCCTTCCCTTCTCCGGTTGCCTTCCCGGGCCCCTTACACTCCACAGTCCCGGT
CCCGCCATGTCCCAGAAACAAGAAGAAGAGAACCCTGCGGAGGAGACCGGCGAGGAGAAGCAGGACACGCAGGAGAAAGAAGGTATTCTG
CCTGAGAGAGCTGAAGAGGCAAAGCTAAAGGCCAAATACCCAAGCCTAGGACAAAAGCCTGGAGGCTCCGACTTCCTCATGAAGAGACTC
CAGAAAGGGGATTATAAATCATTACATTGGAGTGTGCTTCTCTGTGCGGATGAAATGCAAAAGTACTTTGACTCAGGAGACTACAACATG
GCCAAAGCCAAGATGAAGAATAAGCAGCTGCCAAGTGCAGGACCAGACAAGAACCTGGTGACTGGTGATCACATCCCCACCCCACAGGAT
CTGCCCCAGAGAAAGTCCTCGCTCGTCACCAGCAAGCTTGCGGGAGAAGAGCAAGTTAGTACCTTGTACCAAAACATCAACCTTGTGGAG
CCAAGATTAATTCAGCCATATGAACATGTTATAAAGAACTTCATCCGTGAGATCAGACTTCAAAGCACAGAAATGGAAAATTTGGCCATT
GCGGTGAAGAGAGCCCAGGACAAGGCAGCTATGCAGTTGAGTGAGTTGGAAGAGGAAATGGATCAGAGGATTCAGGCTGCAGAACATAAG
ACACGGAAAGACGAAAAACGCAAAGCTGAGGAAGCCCTCAGTGACCTCAGACGTCAGTATGAAACTGAAGTAGGAGATCTGCAGGTGACC
ATTAAAAAGCTAAGAAAGCTCGAAGAACAATCAAAACGCGTAAGTCAAAAGGAAGATGTGGCTGCATTGAAAAAACAAATTTATGATTTA
TCAATGGAAAACCAGAAAGTTAAGAAAGACCTTTTAGAAGCACAGACAAACATAGCCTTTCTTCAGAGTGAGTTAGATGCTTTGAAAAGT
GATTATGCTGATCAGAGTCTGAATACTGAAAGGGATCTGGAAATAATCCGAGCATACACAGAAGATCGAAATAGTCTTGAGAGGCAAATT
GAAATACTCCAAACAGCTAACCGGAAGCTACATGACAGTAATGATGGCCTTAGAAGTGCCCTTGAAAACAGTTATAGCAAGTTCAACAGA
TCTTTGCATATAAATAATATCTCACCAGGGAATACAATTTCTAGAAGCAGTCCCAAATTCATTGGTCATTCCCCTCAACCTCTAGGCTAT
GACAGGTCATCCCGCTCTTCCTATGTGGATGAGGACTGTGACTCCCTGGCCCTCTGTGATCCTCTGCAGAGGACAAATTGTGAAGTTGAC
AGCCTGCCTGAAAGCTGCTTCGACAGCGGCTTGTCTACCTTGAGAGATCCCAATGAGTATGACTCAGAAGTGGAATACAAGCACCAGAGG
GGATTTCAGAGGTCACACGGGGTGCAGGAGAGCTTTGGAGGTGATGCTTCAGACACAGATGTTCCTGACATAAGGGATGAAGAGACATTT
GGTTTAGAAGATGTGGCTTCCGTCTTAGACTGGAAGCCCCAAGGGTCTGTTAGTGAAGGCAGCATTGTTAGTTCATCAAGAAAGCCCATC
TCAGCACTCTCGCCCCAGACAGACCTGGTAGATGACAACGCTAAATCTTTTAGCTCACAGAAGGCTTACAAGATTGTACTTGCTGGGGAC
GCTGCAGTGGGGAAGTCTAGTTTCCTCATGAGACTTTGCAAGAATGAATTTCGAGAAAATATAAGCGCCACCCTGGGAGTTGATTTCCAA
ATGAAAACCCTCATTGTGGATGGAGAACGAACAGTTCTGCAGCTCTGGGATACAGCTGGTCAGGAGAGATTCAGAAGTATTGCCAAGTCT
TACTTCAGAAAGGCAGATGGTGTTTTGCTGCTGTATGATGTTACATGTGAGAAAAGCTTTCTTAACATACGAGAATGGGTAGATATGATT
GAGGATGCAGCCCATGAGACTGTTCCCATTATGCTGGTAGGAAACAAGGCTGACATTCGTGACACTGCTGCTACAGAGGGACAAAAATGT
GTCCCAGGGCACTTTGGAGAGAAACTGGCCATGACGTATGGGGCATTATTCTGTGAAACAAGTGCCAAAGATGGTTCTAACATAGTGGAG
GCTGTTCTGCACCTTGCTCGAGAAGTGAAAAAGAGAACTGACAAGGATGACAGCAGATCCATTACCAATCTAACCGGGACCAATTCCAAA
AAGTCACCACAGATGAAGAATTGTTGCAATGGCTAAATCCCAAACATCCTTGGCCTGTGAAGTCTTCATTTCCAGAATACTGAATTTGTG
TGACTTATTTGGCTCTTAACAGAGTGGCACATCCTACTGACACTGTCCTATGGAGAGTTACAGTGCAGGAAACCTGAACCCAGCTCTCAG
GTCCCTCTGGAACTTTGGCTCTTCTTTGTTTTGTCTCAGTGAGTGATTTGGGCCCTCTGGCTAAATAGACTAGTCATGTCCTTACAGGTC
TTAAAAGATAACATGTAAATGTTTTTAAAATGGTAAAAAAAAAGAAAAGAAAAGAAATCACATGCTCAGATCAAAGCTGTAGAGGAAACT
GACATAATTAGATTCATGTGGTAGCTGAATTAGGTTACCCACAAAGTCAGCATTTAAATATTTGATACTAAAGTTCTAGTAAGAAGGGAT
TCTCATCCTAGCTTTGCTGTTAACTGGCCTTGTGACCTTGGACATGTCACAAGCCCATGTCGGATCTGTTTCTTCATCTGTAAAATGTGC
AGCTTGCCCTCAAAGGCCTTGCAGCCCTTGGCACCTCAGATTCTGTGGGAAGCAGTAGGACAGAGAGTGTGGTGGCCCACAGTTAATAAT
AGAACTATGGTTATTCCTGCTTTTTAATATTGGAGTATTGATTTTTCTCACTTCTGAAATAAGGACAGAATTTGATTAAAAAATGGAAAC
AGAAATATCTATTTTTTATGTATAAAGAAACATGTTTGAGACAAAAATAGTTGTATATAAAAGGATATTTCATAATCTCAGAATAGTTAC
AAAGCTCACTGCTTGAATTTGGTGTTAAAAATTCTAATGGAAACATGTAAAGCCACATACTACTGAAAGCACAATGCCCAGGAAAGTTGT
CACTCTTCACTTAAGGGAGTGGTTGCCAGGGGCTGAGAAAGGGAGGATGGGGAGTGACTGCTAATAGGTATGTGGTTTCTTTGGGCGATG
ATGAGAATGTTCTGGAATTGGAATAGTGGTGATAGTTGTATAACTGTTTGAATGTACTAGGAACCACTGAATTGTATACTTTGAAAGGGT
GAATTTTATGGTTGTGAATTATCTCACTAAAAAAAATGCTAGTACTTAGAGTGATGTAACATTTTGCAAAATTTTCATTTTCGTATCCCT
GCTGATTTCAAACCTTCCCATGGTTTAGAAGCATAACCTGTAATGTAATGCAAGTCCCCTAACTCCCTGGTTGCTAACATTAACTTCCTT
AAGTAATAATCAATGAAAGAAATTCTATGCATGGTTTTGAAATAATATCCTTGAAAGAGGAATCACCATTAGGAAAGGTGAGTCAGGGTC
CTTTGTTTAATGTGACTAGTGGCTCATCATCACCAGTGACCTGGTTGGGCCTACTCTCCTTCCAGAACCTGCATTGCTTCCCAGACCTCC
CCACTGAGATGCCTCTAAGAGCCAAAGGAGTCAACACTTGAGCCTAGGGTGGGCTACAACAAAAGATTCTAATTTACCTTGCTTCATCTA
GGTCCAGGCCCCAAGTAGCTTGCTGAAGGAACTTAAAAAGTAGCTGTTATTTATTGTATTGTATAAGCTAAAAACATTTATTTTTGTTGA
ATCGAAACAATTCCATGTAGCAATCTTTTTTCTGTTCACGGTGTTTGTGATAGAACCTTAAATTCCGCAAGCATCAGTTTTTTGAAAAAA
TGGGAATTGACCGGATAGTTACAGGCAAAGATTATAAATAGCTACAACATCATTTAACTTTTATAAACATGCCTTCTCTCTATTGAAGAC
ATCTGATATTTTTGCTGGAAAGTTGGATCTATCCTCAGTAACTCTGCCATGAATTCCTGTTTCCTGGTTCCAGAAAAAGAAAAGATTACA
TTTCTGATCATAAAGAATGTCTTGCATATGGGAAATTTTTCAAAATAAGGGGGGTATTATTTATGTGGCATGGGAAAACTTTTGCCATGG
CTGTTTGTCTTAGTGGCATCTTTTGATGACATTGGATCAGATATATGTAGATGCTGATATATGGGACACATGTTTAGGTTTTGGTGCAGT
TGCACAAAACTGTGTTAGTTTATATGTTACTGTGTTGCCTTTATTTATTCTCTCCAAAGTGTCTCTTTATATTTGTTTTACAATCTGTGA
AAGAGTATACCATAATACAGAAGTATTTTCATAGTCTTTACCTCTGGATTGTCCTGTCAGTATAGCCACGTTGATGAGATTACACCAGTG
CCTTTGATGGTCAACCAATCATCTTTAAGTATTTGAGCCCTGATAAATATTTTGGTAACATAATCCAAATTAGAGACTTAGAGCTCTGGT
TAGCAATCATGTTTAAAGAGAAGCTTCTTAAAGCTCTGTATGCTGGGAGATTCATGATTATTACCAACGTTTTGATTTCATGAAGGTGTT
CTCAAATTTAAAGCACATTTTCAGTAAGAACAAAAATATTTAATGTTTTTATCTTAGACTTGATACATTTGCATATTACTATGGAAGTTA
TTCACCTTGTCCCTGTTTTTCTTTAAGATATTTTAAAATCATAGTTATACTACAGTCCTTTTTTAAATGTATCCTGATACATTGTAAAAT
ATTTTAATTTCATTGTGGAAAATAATGTTGGATAAGGAGATATTTTTCACTGTTAACTTTTAGCCCATGCATTTTCATAATTTATTTTTT
TCACTTGCTGCTTTATATGACATATGTGACATTTGATTATTTAACACTTGATGTGATCTGCATAAACCCAAGTTGCACAACCCTCCTGCT
GAAGATAAAATTGAGGTTAAAGATAAAGATTTATTTTCATATTTGTACAGTGATCGGCTTCAGTGATGGTTTTTGTGGGCATTTATTGTG
TGTGTGTAAGAAATTTCATATGTATATATTAAGTAGGCCTCTGAGTATTGAATAATTGTTTTATGATTTTGATTTATATGGTTTACATTT
TCATTGTGTGGGCCATATTTCGTTTATACTGTTTATTTCTCTTCAAACCTTAATAATTATACCATAAAGTGTAATTTTTATAGCAATGCA

>In-frame_ENST00000369016_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(amino acids)=755AA_start in transcript=18_stop in transcript=2285
MSPFPLPLPFSGCLPGPLTLHSPGPAMSQKQEEENPAEETGEEKQDTQEKEGILPERAEEAKLKAKYPSLGQKPGGSDFLMKRLQKGDYK
SLHWSVLLCADEMQKYFDSGDYNMAKAKMKNKQLPSAGPDKNLVTGDHIPTPQDLPQRKSSLVTSKLAGEEQVSTLYQNINLVEPRLIQP
YEHVIKNFIREIRLQSTEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYETEVGDLQVTIKKLRK
LEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFLQSELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQIEILQTA
NRKLHDSNDGLRSALENSYSKFNRSLHINNISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDPLQRTNCEVDSLPESC
FDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDVPDIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKPISALSPQ
TDLVDDNAKSFSSQKAYKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQERFRSIAKSYFRKAD
GVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLA

--------------------------------------------------------------
>In-frame_ENST00000369014_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(transcript)=5360nt_BP=476nt
ATTTTGACTGAGCAACCCTAGTGACAGGAGCCGAAGCAGCAGCGCAGGTTGTCCCCGTTTCCCCTCCCCCTTCCCTTCTCCGGTTGCCTT
CCCGGGCCCCTTACACTCCACAGTCCCGGTCCCGCCATGTCCCAGAAACAAGAAGAAGAGAACCCTGCGGAGGAGACCGGCGAGGAGAAG
CAGGACACGCAGGAGAAAGAAGGTATTCTGCCTGAGAGAGCTGAAGAGGCAAAGCTAAAGGCCAAATACCCAAGCCTAGGACAAAAGCCT
GGAGGCTCCGACTTCCTCATGAAGAGACTCCAGAAAGGGCAAAAGTACTTTGACTCAGGAGACTACAACATGGCCAAAGCCAAGATGAAG
AATAAGCAGCTGCCAAGTGCAGGACCAGACAAGAACCTGGTGACTGGTGATCACATCCCCACCCCACAGGATCTGCCCCAGAGAAAGTCC
TCGCTCGTCACCAGCAAGCTTGCGGGAGAAGAGCAAGTTAGTACCTTGTACCAAAACATCAACCTTGTGGAGCCAAGATTAATTCAGCCA
TATGAACATGTTATAAAGAACTTCATCCGTGAGATCAGACTTCAAAGCACAGAAATGGAAAATTTGGCCATTGCGGTGAAGAGAGCCCAG
GACAAGGCAGCTATGCAGTTGAGTGAGTTGGAAGAGGAAATGGATCAGAGGATTCAGGCTGCAGAACATAAGACACGGAAAGACGAAAAA
CGCAAAGCTGAGGAAGCCCTCAGTGACCTCAGACGTCAGTATGAAACTGAAGTAGGAGATCTGCAGGTGACCATTAAAAAGCTAAGAAAG
CTCGAAGAACAATCAAAACGCGTAAGTCAAAAGGAAGATGTGGCTGCATTGAAAAAACAAATTTATGATTTATCAATGGAAAACCAGAAA
GTTAAGAAAGACCTTTTAGAAGCACAGACAAACATAGCCTTTCTTCAGAGTGAGTTAGATGCTTTGAAAAGTGATTATGCTGATCAGAGT
CTGAATACTGAAAGGGATCTGGAAATAATCCGAGCATACACAGAAGATCGAAATAGTCTTGAGAGGCAAATTGAAATACTCCAAACAGCT
AACCGGAAGCTACATGACAGTAATGATGGCCTTAGAAGTGCCCTTGAAAACAGTTATAGCAAGTTCAACAGATCTTTGCATATAAATAAT
ATCTCACCAGGGAATACAATTTCTAGAAGCAGTCCCAAATTCATTGGTCATTCCCCTCAACCTCTAGGCTATGACAGGTCATCCCGCTCT
TCCTATGTGGATGAGGACTGTGACTCCCTGGCCCTCTGTGATCCTCTGCAGAGGACAAATTGTGAAGTTGACAGCCTGCCTGAAAGCTGC
TTCGACAGCGGCTTGTCTACCTTGAGAGATCCCAATGAGTATGACTCAGAAGTGGAATACAAGCACCAGAGGGGATTTCAGAGGTCACAC
GGGGTGCAGGAGAGCTTTGGAGGTGATGCTTCAGACACAGATGTTCCTGACATAAGGGATGAAGAGACATTTGGTTTAGAAGATGTGGCT
TCCGTCTTAGACTGGAAGCCCCAAGGGTCTGTTAGTGAAGGCAGCATTGTTAGTTCATCAAGAAAGCCCATCTCAGCACTCTCGCCCCAG
ACAGACCTGGTAGATGACAACGCTAAATCTTTTAGCTCACAGAAGGCTTACAAGATTGTACTTGCTGGGGACGCTGCAGTGGGGAAGTCT
AGTTTCCTCATGAGACTTTGCAAGAATGAATTTCGAGAAAATATAAGCGCCACCCTGGGAGTTGATTTCCAAATGAAAACCCTCATTGTG
GATGGAGAACGAACAGTTCTGCAGCTCTGGGATACAGCTGGTCAGGAGAGATTCAGAAGTATTGCCAAGTCTTACTTCAGAAAGGCAGAT
GGTGTTTTGCTGCTGTATGATGTTACATGTGAGAAAAGCTTTCTTAACATACGAGAATGGGTAGATATGATTGAGGATGCAGCCCATGAG
ACTGTTCCCATTATGCTGGTAGGAAACAAGGCTGACATTCGTGACACTGCTGCTACAGAGGGACAAAAATGTGTCCCAGGGCACTTTGGA
GAGAAACTGGCCATGACGTATGGGGCATTATTCTGTGAAACAAGTGCCAAAGATGGTTCTAACATAGTGGAGGCTGTTCTGCACCTTGCT
CGAGAAGTGAAAAAGAGAACTGACAAGGATGACAGCAGATCCATTACCAATCTAACCGGGACCAATTCCAAAAAGTCACCACAGATGAAG
AATTGTTGCAATGGCTAAATCCCAAACATCCTTGGCCTGTGAAGTCTTCATTTCCAGAATACTGAATTTGTGTGACTTATTTGGCTCTTA
ACAGAGTGGCACATCCTACTGACACTGTCCTATGGAGAGTTACAGTGCAGGAAACCTGAACCCAGCTCTCAGGTCCCTCTGGAACTTTGG
CTCTTCTTTGTTTTGTCTCAGTGAGTGATTTGGGCCCTCTGGCTAAATAGACTAGTCATGTCCTTACAGGTCTTAAAAGATAACATGTAA
ATGTTTTTAAAATGGTAAAAAAAAAGAAAAGAAAAGAAATCACATGCTCAGATCAAAGCTGTAGAGGAAACTGACATAATTAGATTCATG
TGGTAGCTGAATTAGGTTACCCACAAAGTCAGCATTTAAATATTTGATACTAAAGTTCTAGTAAGAAGGGATTCTCATCCTAGCTTTGCT
GTTAACTGGCCTTGTGACCTTGGACATGTCACAAGCCCATGTCGGATCTGTTTCTTCATCTGTAAAATGTGCAGCTTGCCCTCAAAGGCC
TTGCAGCCCTTGGCACCTCAGATTCTGTGGGAAGCAGTAGGACAGAGAGTGTGGTGGCCCACAGTTAATAATAGAACTATGGTTATTCCT
GCTTTTTAATATTGGAGTATTGATTTTTCTCACTTCTGAAATAAGGACAGAATTTGATTAAAAAATGGAAACAGAAATATCTATTTTTTA
TGTATAAAGAAACATGTTTGAGACAAAAATAGTTGTATATAAAAGGATATTTCATAATCTCAGAATAGTTACAAAGCTCACTGCTTGAAT
TTGGTGTTAAAAATTCTAATGGAAACATGTAAAGCCACATACTACTGAAAGCACAATGCCCAGGAAAGTTGTCACTCTTCACTTAAGGGA
GTGGTTGCCAGGGGCTGAGAAAGGGAGGATGGGGAGTGACTGCTAATAGGTATGTGGTTTCTTTGGGCGATGATGAGAATGTTCTGGAAT
TGGAATAGTGGTGATAGTTGTATAACTGTTTGAATGTACTAGGAACCACTGAATTGTATACTTTGAAAGGGTGAATTTTATGGTTGTGAA
TTATCTCACTAAAAAAAATGCTAGTACTTAGAGTGATGTAACATTTTGCAAAATTTTCATTTTCGTATCCCTGCTGATTTCAAACCTTCC
CATGGTTTAGAAGCATAACCTGTAATGTAATGCAAGTCCCCTAACTCCCTGGTTGCTAACATTAACTTCCTTAAGTAATAATCAATGAAA
GAAATTCTATGCATGGTTTTGAAATAATATCCTTGAAAGAGGAATCACCATTAGGAAAGGTGAGTCAGGGTCCTTTGTTTAATGTGACTA
GTGGCTCATCATCACCAGTGACCTGGTTGGGCCTACTCTCCTTCCAGAACCTGCATTGCTTCCCAGACCTCCCCACTGAGATGCCTCTAA
GAGCCAAAGGAGTCAACACTTGAGCCTAGGGTGGGCTACAACAAAAGATTCTAATTTACCTTGCTTCATCTAGGTCCAGGCCCCAAGTAG
CTTGCTGAAGGAACTTAAAAAGTAGCTGTTATTTATTGTATTGTATAAGCTAAAAACATTTATTTTTGTTGAATCGAAACAATTCCATGT
AGCAATCTTTTTTCTGTTCACGGTGTTTGTGATAGAACCTTAAATTCCGCAAGCATCAGTTTTTTGAAAAAATGGGAATTGACCGGATAG
TTACAGGCAAAGATTATAAATAGCTACAACATCATTTAACTTTTATAAACATGCCTTCTCTCTATTGAAGACATCTGATATTTTTGCTGG
AAAGTTGGATCTATCCTCAGTAACTCTGCCATGAATTCCTGTTTCCTGGTTCCAGAAAAAGAAAAGATTACATTTCTGATCATAAAGAAT
GTCTTGCATATGGGAAATTTTTCAAAATAAGGGGGGTATTATTTATGTGGCATGGGAAAACTTTTGCCATGGCTGTTTGTCTTAGTGGCA
TCTTTTGATGACATTGGATCAGATATATGTAGATGCTGATATATGGGACACATGTTTAGGTTTTGGTGCAGTTGCACAAAACTGTGTTAG
TTTATATGTTACTGTGTTGCCTTTATTTATTCTCTCCAAAGTGTCTCTTTATATTTGTTTTACAATCTGTGAAAGAGTATACCATAATAC
AGAAGTATTTTCATAGTCTTTACCTCTGGATTGTCCTGTCAGTATAGCCACGTTGATGAGATTACACCAGTGCCTTTGATGGTCAACCAA
TCATCTTTAAGTATTTGAGCCCTGATAAATATTTTGGTAACATAATCCAAATTAGAGACTTAGAGCTCTGGTTAGCAATCATGTTTAAAG
AGAAGCTTCTTAAAGCTCTGTATGCTGGGAGATTCATGATTATTACCAACGTTTTGATTTCATGAAGGTGTTCTCAAATTTAAAGCACAT
TTTCAGTAAGAACAAAAATATTTAATGTTTTTATCTTAGACTTGATACATTTGCATATTACTATGGAAGTTATTCACCTTGTCCCTGTTT
TTCTTTAAGATATTTTAAAATCATAGTTATACTACAGTCCTTTTTTAAATGTATCCTGATACATTGTAAAATATTTTAATTTCATTGTGG
AAAATAATGTTGGATAAGGAGATATTTTTCACTGTTAACTTTTAGCCCATGCATTTTCATAATTTATTTTTTTCACTTGCTGCTTTATAT
GACATATGTGACATTTGATTATTTAACACTTGATGTGATCTGCATAAACCCAAGTTGCACAACCCTCCTGCTGAAGATAAAATTGAGGTT
AAAGATAAAGATTTATTTTCATATTTGTACAGTGATCGGCTTCAGTGATGGTTTTTGTGGGCATTTATTGTGTGTGTGTAAGAAATTTCA
TATGTATATATTAAGTAGGCCTCTGAGTATTGAATAATTGTTTTATGATTTTGATTTATATGGTTTACATTTTCATTGTGTGGGCCATAT
TTCGTTTATACTGTTTATTTCTCTTCAAACCTTAATAATTATACCATAAAGTGTAATTTTTATAGCAATGCAAATGTCTAAGGAACTACA

>In-frame_ENST00000369014_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(amino acids)=739AA_start in transcript=48_stop in transcript=2267
MSPFPLPLPFSGCLPGPLTLHSPGPAMSQKQEEENPAEETGEEKQDTQEKEGILPERAEEAKLKAKYPSLGQKPGGSDFLMKRLQKGQKY
FDSGDYNMAKAKMKNKQLPSAGPDKNLVTGDHIPTPQDLPQRKSSLVTSKLAGEEQVSTLYQNINLVEPRLIQPYEHVIKNFIREIRLQS
TEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYETEVGDLQVTIKKLRKLEEQSKRVSQKEDVAA
LKKQIYDLSMENQKVKKDLLEAQTNIAFLQSELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQIEILQTANRKLHDSNDGLRSALE
NSYSKFNRSLHINNISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDPLQRTNCEVDSLPESCFDSGLSTLRDPNEYDS
EVEYKHQRGFQRSHGVQESFGGDASDTDVPDIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKPISALSPQTDLVDDNAKSFSSQKA
YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLN
IREWVDMIEDAAHETVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSIT

--------------------------------------------------------------
>In-frame_ENST00000369009_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(transcript)=5429nt_BP=545nt
ATTTTGACTGAGCAACCCTAGTGACAGGAGCCGAAGCAGCAGCGCAGGTTGTCCCCGTTTCCCCTCCCCCTTCCCTTCTCCGGTTGCCTT
CCCGGGCCCCTTACACTCCACAGTCCCGGTCCCGCCATGTCCCAGAAACAAGAAGAAGAGAACCCTGCGGAGGAGACCGGCGAGGAGAAG
CAGGACACGCAGGAGAAAGAAGGTATTCTGCCTGAGAGAGCTGAAGAGGCAAAGCTAAAGGCCAAATACCCAAGCCTAGGACAAAAGCCT
GGAGGCTCCGACTTCCTCATGAAGAGACTCCAGAAAGGGGTATGGGGCATAGTCTCTTACCCTCTTTCTTTGGAGCTAAAGGAGGTTCTT
CGAATGAAGTCTGTAGAGCAAAAGTACTTTGACTCAGGAGACTACAACATGGCCAAAGCCAAGATGAAGAATAAGCAGCTGCCAAGTGCA
GGACCAGACAAGAACCTGGTGACTGGTGATCACATCCCCACCCCACAGGATCTGCCCCAGAGAAAGTCCTCGCTCGTCACCAGCAAGCTT
GCGGGAGAAGAGCAAGTTAGTACCTTGTACCAAAACATCAACCTTGTGGAGCCAAGATTAATTCAGCCATATGAACATGTTATAAAGAAC
TTCATCCGTGAGATCAGACTTCAAAGCACAGAAATGGAAAATTTGGCCATTGCGGTGAAGAGAGCCCAGGACAAGGCAGCTATGCAGTTG
AGTGAGTTGGAAGAGGAAATGGATCAGAGGATTCAGGCTGCAGAACATAAGACACGGAAAGACGAAAAACGCAAAGCTGAGGAAGCCCTC
AGTGACCTCAGACGTCAGTATGAAACTGAAGTAGGAGATCTGCAGGTGACCATTAAAAAGCTAAGAAAGCTCGAAGAACAATCAAAACGC
GTAAGTCAAAAGGAAGATGTGGCTGCATTGAAAAAACAAATTTATGATTTATCAATGGAAAACCAGAAAGTTAAGAAAGACCTTTTAGAA
GCACAGACAAACATAGCCTTTCTTCAGAGTGAGTTAGATGCTTTGAAAAGTGATTATGCTGATCAGAGTCTGAATACTGAAAGGGATCTG
GAAATAATCCGAGCATACACAGAAGATCGAAATAGTCTTGAGAGGCAAATTGAAATACTCCAAACAGCTAACCGGAAGCTACATGACAGT
AATGATGGCCTTAGAAGTGCCCTTGAAAACAGTTATAGCAAGTTCAACAGATCTTTGCATATAAATAATATCTCACCAGGGAATACAATT
TCTAGAAGCAGTCCCAAATTCATTGGTCATTCCCCTCAACCTCTAGGCTATGACAGGTCATCCCGCTCTTCCTATGTGGATGAGGACTGT
GACTCCCTGGCCCTCTGTGATCCTCTGCAGAGGACAAATTGTGAAGTTGACAGCCTGCCTGAAAGCTGCTTCGACAGCGGCTTGTCTACC
TTGAGAGATCCCAATGAGTATGACTCAGAAGTGGAATACAAGCACCAGAGGGGATTTCAGAGGTCACACGGGGTGCAGGAGAGCTTTGGA
GGTGATGCTTCAGACACAGATGTTCCTGACATAAGGGATGAAGAGACATTTGGTTTAGAAGATGTGGCTTCCGTCTTAGACTGGAAGCCC
CAAGGGTCTGTTAGTGAAGGCAGCATTGTTAGTTCATCAAGAAAGCCCATCTCAGCACTCTCGCCCCAGACAGACCTGGTAGATGACAAC
GCTAAATCTTTTAGCTCACAGAAGGCTTACAAGATTGTACTTGCTGGGGACGCTGCAGTGGGGAAGTCTAGTTTCCTCATGAGACTTTGC
AAGAATGAATTTCGAGAAAATATAAGCGCCACCCTGGGAGTTGATTTCCAAATGAAAACCCTCATTGTGGATGGAGAACGAACAGTTCTG
CAGCTCTGGGATACAGCTGGTCAGGAGAGATTCAGAAGTATTGCCAAGTCTTACTTCAGAAAGGCAGATGGTGTTTTGCTGCTGTATGAT
GTTACATGTGAGAAAAGCTTTCTTAACATACGAGAATGGGTAGATATGATTGAGGATGCAGCCCATGAGACTGTTCCCATTATGCTGGTA
GGAAACAAGGCTGACATTCGTGACACTGCTGCTACAGAGGGACAAAAATGTGTCCCAGGGCACTTTGGAGAGAAACTGGCCATGACGTAT
GGGGCATTATTCTGTGAAACAAGTGCCAAAGATGGTTCTAACATAGTGGAGGCTGTTCTGCACCTTGCTCGAGAAGTGAAAAAGAGAACT
GACAAGGATGACAGCAGATCCATTACCAATCTAACCGGGACCAATTCCAAAAAGTCACCACAGATGAAGAATTGTTGCAATGGCTAAATC
CCAAACATCCTTGGCCTGTGAAGTCTTCATTTCCAGAATACTGAATTTGTGTGACTTATTTGGCTCTTAACAGAGTGGCACATCCTACTG
ACACTGTCCTATGGAGAGTTACAGTGCAGGAAACCTGAACCCAGCTCTCAGGTCCCTCTGGAACTTTGGCTCTTCTTTGTTTTGTCTCAG
TGAGTGATTTGGGCCCTCTGGCTAAATAGACTAGTCATGTCCTTACAGGTCTTAAAAGATAACATGTAAATGTTTTTAAAATGGTAAAAA
AAAAGAAAAGAAAAGAAATCACATGCTCAGATCAAAGCTGTAGAGGAAACTGACATAATTAGATTCATGTGGTAGCTGAATTAGGTTACC
CACAAAGTCAGCATTTAAATATTTGATACTAAAGTTCTAGTAAGAAGGGATTCTCATCCTAGCTTTGCTGTTAACTGGCCTTGTGACCTT
GGACATGTCACAAGCCCATGTCGGATCTGTTTCTTCATCTGTAAAATGTGCAGCTTGCCCTCAAAGGCCTTGCAGCCCTTGGCACCTCAG
ATTCTGTGGGAAGCAGTAGGACAGAGAGTGTGGTGGCCCACAGTTAATAATAGAACTATGGTTATTCCTGCTTTTTAATATTGGAGTATT
GATTTTTCTCACTTCTGAAATAAGGACAGAATTTGATTAAAAAATGGAAACAGAAATATCTATTTTTTATGTATAAAGAAACATGTTTGA
GACAAAAATAGTTGTATATAAAAGGATATTTCATAATCTCAGAATAGTTACAAAGCTCACTGCTTGAATTTGGTGTTAAAAATTCTAATG
GAAACATGTAAAGCCACATACTACTGAAAGCACAATGCCCAGGAAAGTTGTCACTCTTCACTTAAGGGAGTGGTTGCCAGGGGCTGAGAA
AGGGAGGATGGGGAGTGACTGCTAATAGGTATGTGGTTTCTTTGGGCGATGATGAGAATGTTCTGGAATTGGAATAGTGGTGATAGTTGT
ATAACTGTTTGAATGTACTAGGAACCACTGAATTGTATACTTTGAAAGGGTGAATTTTATGGTTGTGAATTATCTCACTAAAAAAAATGC
TAGTACTTAGAGTGATGTAACATTTTGCAAAATTTTCATTTTCGTATCCCTGCTGATTTCAAACCTTCCCATGGTTTAGAAGCATAACCT
GTAATGTAATGCAAGTCCCCTAACTCCCTGGTTGCTAACATTAACTTCCTTAAGTAATAATCAATGAAAGAAATTCTATGCATGGTTTTG
AAATAATATCCTTGAAAGAGGAATCACCATTAGGAAAGGTGAGTCAGGGTCCTTTGTTTAATGTGACTAGTGGCTCATCATCACCAGTGA
CCTGGTTGGGCCTACTCTCCTTCCAGAACCTGCATTGCTTCCCAGACCTCCCCACTGAGATGCCTCTAAGAGCCAAAGGAGTCAACACTT
GAGCCTAGGGTGGGCTACAACAAAAGATTCTAATTTACCTTGCTTCATCTAGGTCCAGGCCCCAAGTAGCTTGCTGAAGGAACTTAAAAA
GTAGCTGTTATTTATTGTATTGTATAAGCTAAAAACATTTATTTTTGTTGAATCGAAACAATTCCATGTAGCAATCTTTTTTCTGTTCAC
GGTGTTTGTGATAGAACCTTAAATTCCGCAAGCATCAGTTTTTTGAAAAAATGGGAATTGACCGGATAGTTACAGGCAAAGATTATAAAT
AGCTACAACATCATTTAACTTTTATAAACATGCCTTCTCTCTATTGAAGACATCTGATATTTTTGCTGGAAAGTTGGATCTATCCTCAGT
AACTCTGCCATGAATTCCTGTTTCCTGGTTCCAGAAAAAGAAAAGATTACATTTCTGATCATAAAGAATGTCTTGCATATGGGAAATTTT
TCAAAATAAGGGGGGTATTATTTATGTGGCATGGGAAAACTTTTGCCATGGCTGTTTGTCTTAGTGGCATCTTTTGATGACATTGGATCA
GATATATGTAGATGCTGATATATGGGACACATGTTTAGGTTTTGGTGCAGTTGCACAAAACTGTGTTAGTTTATATGTTACTGTGTTGCC
TTTATTTATTCTCTCCAAAGTGTCTCTTTATATTTGTTTTACAATCTGTGAAAGAGTATACCATAATACAGAAGTATTTTCATAGTCTTT
ACCTCTGGATTGTCCTGTCAGTATAGCCACGTTGATGAGATTACACCAGTGCCTTTGATGGTCAACCAATCATCTTTAAGTATTTGAGCC
CTGATAAATATTTTGGTAACATAATCCAAATTAGAGACTTAGAGCTCTGGTTAGCAATCATGTTTAAAGAGAAGCTTCTTAAAGCTCTGT
ATGCTGGGAGATTCATGATTATTACCAACGTTTTGATTTCATGAAGGTGTTCTCAAATTTAAAGCACATTTTCAGTAAGAACAAAAATAT
TTAATGTTTTTATCTTAGACTTGATACATTTGCATATTACTATGGAAGTTATTCACCTTGTCCCTGTTTTTCTTTAAGATATTTTAAAAT
CATAGTTATACTACAGTCCTTTTTTAAATGTATCCTGATACATTGTAAAATATTTTAATTTCATTGTGGAAAATAATGTTGGATAAGGAG
ATATTTTTCACTGTTAACTTTTAGCCCATGCATTTTCATAATTTATTTTTTTCACTTGCTGCTTTATATGACATATGTGACATTTGATTA
TTTAACACTTGATGTGATCTGCATAAACCCAAGTTGCACAACCCTCCTGCTGAAGATAAAATTGAGGTTAAAGATAAAGATTTATTTTCA
TATTTGTACAGTGATCGGCTTCAGTGATGGTTTTTGTGGGCATTTATTGTGTGTGTGTAAGAAATTTCATATGTATATATTAAGTAGGCC
TCTGAGTATTGAATAATTGTTTTATGATTTTGATTTATATGGTTTACATTTTCATTGTGTGGGCCATATTTCGTTTATACTGTTTATTTC
TCTTCAAACCTTAATAATTATACCATAAAGTGTAATTTTTATAGCAATGCAAATGTCTAAGGAACTACAAATATTTTCTACGTTGTAAAT

>In-frame_ENST00000369009_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(amino acids)=762AA_start in transcript=48_stop in transcript=2336
MSPFPLPLPFSGCLPGPLTLHSPGPAMSQKQEEENPAEETGEEKQDTQEKEGILPERAEEAKLKAKYPSLGQKPGGSDFLMKRLQKGVWG
IVSYPLSLELKEVLRMKSVEQKYFDSGDYNMAKAKMKNKQLPSAGPDKNLVTGDHIPTPQDLPQRKSSLVTSKLAGEEQVSTLYQNINLV
EPRLIQPYEHVIKNFIREIRLQSTEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYETEVGDLQV
TIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFLQSELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQ
IEILQTANRKLHDSNDGLRSALENSYSKFNRSLHINNISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDPLQRTNCEV
DSLPESCFDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDVPDIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKP
ISALSPQTDLVDDNAKSFSSQKAYKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQERFRSIAK
SYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIV

--------------------------------------------------------------
>In-frame_ENST00000339643_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(transcript)=5388nt_BP=504nt
GTGACAGGAGCCGAAGCAGCAGCGCAGGTTGTCCCCGTTTCCCCTCCCCCTTCCCTTCTCCGGTTGCCTTCCCGGGCCCCTTACACTCCA
CAGTCCCGGTCCCGCCATGTCCCAGAAACAAGAAGAAGAGAACCCTGCGGAGGAGACCGGCGAGGAGAAGCAGGACACGCAGGAGAAAGA
AGGTATTCTGCCTGAGAGAGCTGAAGAGGCAAAGCTAAAGGCCAAATACCCAAGCCTAGGACAAAAGCCTGGAGGCTCCGACTTCCTCAT
GAAGAGACTCCAGAAAGGGGATTATAAATCATTACATTGGAGTGTGCTTCTCTGTGCGGATGAAATGCAAAAGTACTTTGACTCAGGAGA
CTACAACATGGCCAAAGCCAAGATGAAGAATAAGCAGCTGCCAAGTGCAGGACCAGACAAGAACCTGGTGACTGGTGATCACATCCCCAC
CCCACAGGATCTGCCCCAGAGAAAGTCCTCGCTCGTCACCAGCAAGCTTGCGGGAGAAGAGCAAGTTAGTACCTTGTACCAAAACATCAA
CCTTGTGGAGCCAAGATTAATTCAGCCATATGAACATGTTATAAAGAACTTCATCCGTGAGATCAGACTTCAAAGCACAGAAATGGAAAA
TTTGGCCATTGCGGTGAAGAGAGCCCAGGACAAGGCAGCTATGCAGTTGAGTGAGTTGGAAGAGGAAATGGATCAGAGGATTCAGGCTGC
AGAACATAAGACACGGAAAGACGAAAAACGCAAAGCTGAGGAAGCCCTCAGTGACCTCAGACGTCAGTATGAAACTGAAGTAGGAGATCT
GCAGGTGACCATTAAAAAGCTAAGAAAGCTCGAAGAACAATCAAAACGCGTAAGTCAAAAGGAAGATGTGGCTGCATTGAAAAAACAAAT
TTATGATTTATCAATGGAAAACCAGAAAGTTAAGAAAGACCTTTTAGAAGCACAGACAAACATAGCCTTTCTTCAGAGTGAGTTAGATGC
TTTGAAAAGTGATTATGCTGATCAGAGTCTGAATACTGAAAGGGATCTGGAAATAATCCGAGCATACACAGAAGATCGAAATAGTCTTGA
GAGGCAAATTGAAATACTCCAAACAGCTAACCGGAAGCTACATGACAGTAATGATGGCCTTAGAAGTGCCCTTGAAAACAGTTATAGCAA
GTTCAACAGATCTTTGCATATAAATAATATCTCACCAGGGAATACAATTTCTAGAAGCAGTCCCAAATTCATTGGTCATTCCCCTCAACC
TCTAGGCTATGACAGGTCATCCCGCTCTTCCTATGTGGATGAGGACTGTGACTCCCTGGCCCTCTGTGATCCTCTGCAGAGGACAAATTG
TGAAGTTGACAGCCTGCCTGAAAGCTGCTTCGACAGCGGCTTGTCTACCTTGAGAGATCCCAATGAGTATGACTCAGAAGTGGAATACAA
GCACCAGAGGGGATTTCAGAGGTCACACGGGGTGCAGGAGAGCTTTGGAGGTGATGCTTCAGACACAGATGTTCCTGACATAAGGGATGA
AGAGACATTTGGTTTAGAAGATGTGGCTTCCGTCTTAGACTGGAAGCCCCAAGGGTCTGTTAGTGAAGGCAGCATTGTTAGTTCATCAAG
AAAGCCCATCTCAGCACTCTCGCCCCAGACAGACCTGGTAGATGACAACGCTAAATCTTTTAGCTCACAGAAGGCTTACAAGATTGTACT
TGCTGGGGACGCTGCAGTGGGGAAGTCTAGTTTCCTCATGAGACTTTGCAAGAATGAATTTCGAGAAAATATAAGCGCCACCCTGGGAGT
TGATTTCCAAATGAAAACCCTCATTGTGGATGGAGAACGAACAGTTCTGCAGCTCTGGGATACAGCTGGTCAGGAGAGATTCAGAAGTAT
TGCCAAGTCTTACTTCAGAAAGGCAGATGGTGTTTTGCTGCTGTATGATGTTACATGTGAGAAAAGCTTTCTTAACATACGAGAATGGGT
AGATATGATTGAGGATGCAGCCCATGAGACTGTTCCCATTATGCTGGTAGGAAACAAGGCTGACATTCGTGACACTGCTGCTACAGAGGG
ACAAAAATGTGTCCCAGGGCACTTTGGAGAGAAACTGGCCATGACGTATGGGGCATTATTCTGTGAAACAAGTGCCAAAGATGGTTCTAA
CATAGTGGAGGCTGTTCTGCACCTTGCTCGAGAAGTGAAAAAGAGAACTGACAAGGATGACAGCAGATCCATTACCAATCTAACCGGGAC
CAATTCCAAAAAGTCACCACAGATGAAGAATTGTTGCAATGGCTAAATCCCAAACATCCTTGGCCTGTGAAGTCTTCATTTCCAGAATAC
TGAATTTGTGTGACTTATTTGGCTCTTAACAGAGTGGCACATCCTACTGACACTGTCCTATGGAGAGTTACAGTGCAGGAAACCTGAACC
CAGCTCTCAGGTCCCTCTGGAACTTTGGCTCTTCTTTGTTTTGTCTCAGTGAGTGATTTGGGCCCTCTGGCTAAATAGACTAGTCATGTC
CTTACAGGTCTTAAAAGATAACATGTAAATGTTTTTAAAATGGTAAAAAAAAAGAAAAGAAAAGAAATCACATGCTCAGATCAAAGCTGT
AGAGGAAACTGACATAATTAGATTCATGTGGTAGCTGAATTAGGTTACCCACAAAGTCAGCATTTAAATATTTGATACTAAAGTTCTAGT
AAGAAGGGATTCTCATCCTAGCTTTGCTGTTAACTGGCCTTGTGACCTTGGACATGTCACAAGCCCATGTCGGATCTGTTTCTTCATCTG
TAAAATGTGCAGCTTGCCCTCAAAGGCCTTGCAGCCCTTGGCACCTCAGATTCTGTGGGAAGCAGTAGGACAGAGAGTGTGGTGGCCCAC
AGTTAATAATAGAACTATGGTTATTCCTGCTTTTTAATATTGGAGTATTGATTTTTCTCACTTCTGAAATAAGGACAGAATTTGATTAAA
AAATGGAAACAGAAATATCTATTTTTTATGTATAAAGAAACATGTTTGAGACAAAAATAGTTGTATATAAAAGGATATTTCATAATCTCA
GAATAGTTACAAAGCTCACTGCTTGAATTTGGTGTTAAAAATTCTAATGGAAACATGTAAAGCCACATACTACTGAAAGCACAATGCCCA
GGAAAGTTGTCACTCTTCACTTAAGGGAGTGGTTGCCAGGGGCTGAGAAAGGGAGGATGGGGAGTGACTGCTAATAGGTATGTGGTTTCT
TTGGGCGATGATGAGAATGTTCTGGAATTGGAATAGTGGTGATAGTTGTATAACTGTTTGAATGTACTAGGAACCACTGAATTGTATACT
TTGAAAGGGTGAATTTTATGGTTGTGAATTATCTCACTAAAAAAAATGCTAGTACTTAGAGTGATGTAACATTTTGCAAAATTTTCATTT
TCGTATCCCTGCTGATTTCAAACCTTCCCATGGTTTAGAAGCATAACCTGTAATGTAATGCAAGTCCCCTAACTCCCTGGTTGCTAACAT
TAACTTCCTTAAGTAATAATCAATGAAAGAAATTCTATGCATGGTTTTGAAATAATATCCTTGAAAGAGGAATCACCATTAGGAAAGGTG
AGTCAGGGTCCTTTGTTTAATGTGACTAGTGGCTCATCATCACCAGTGACCTGGTTGGGCCTACTCTCCTTCCAGAACCTGCATTGCTTC
CCAGACCTCCCCACTGAGATGCCTCTAAGAGCCAAAGGAGTCAACACTTGAGCCTAGGGTGGGCTACAACAAAAGATTCTAATTTACCTT
GCTTCATCTAGGTCCAGGCCCCAAGTAGCTTGCTGAAGGAACTTAAAAAGTAGCTGTTATTTATTGTATTGTATAAGCTAAAAACATTTA
TTTTTGTTGAATCGAAACAATTCCATGTAGCAATCTTTTTTCTGTTCACGGTGTTTGTGATAGAACCTTAAATTCCGCAAGCATCAGTTT
TTTGAAAAAATGGGAATTGACCGGATAGTTACAGGCAAAGATTATAAATAGCTACAACATCATTTAACTTTTATAAACATGCCTTCTCTC
TATTGAAGACATCTGATATTTTTGCTGGAAAGTTGGATCTATCCTCAGTAACTCTGCCATGAATTCCTGTTTCCTGGTTCCAGAAAAAGA
AAAGATTACATTTCTGATCATAAAGAATGTCTTGCATATGGGAAATTTTTCAAAATAAGGGGGGTATTATTTATGTGGCATGGGAAAACT
TTTGCCATGGCTGTTTGTCTTAGTGGCATCTTTTGATGACATTGGATCAGATATATGTAGATGCTGATATATGGGACACATGTTTAGGTT
TTGGTGCAGTTGCACAAAACTGTGTTAGTTTATATGTTACTGTGTTGCCTTTATTTATTCTCTCCAAAGTGTCTCTTTATATTTGTTTTA
CAATCTGTGAAAGAGTATACCATAATACAGAAGTATTTTCATAGTCTTTACCTCTGGATTGTCCTGTCAGTATAGCCACGTTGATGAGAT
TACACCAGTGCCTTTGATGGTCAACCAATCATCTTTAAGTATTTGAGCCCTGATAAATATTTTGGTAACATAATCCAAATTAGAGACTTA
GAGCTCTGGTTAGCAATCATGTTTAAAGAGAAGCTTCTTAAAGCTCTGTATGCTGGGAGATTCATGATTATTACCAACGTTTTGATTTCA
TGAAGGTGTTCTCAAATTTAAAGCACATTTTCAGTAAGAACAAAAATATTTAATGTTTTTATCTTAGACTTGATACATTTGCATATTACT
ATGGAAGTTATTCACCTTGTCCCTGTTTTTCTTTAAGATATTTTAAAATCATAGTTATACTACAGTCCTTTTTTAAATGTATCCTGATAC
ATTGTAAAATATTTTAATTTCATTGTGGAAAATAATGTTGGATAAGGAGATATTTTTCACTGTTAACTTTTAGCCCATGCATTTTCATAA
TTTATTTTTTTCACTTGCTGCTTTATATGACATATGTGACATTTGATTATTTAACACTTGATGTGATCTGCATAAACCCAAGTTGCACAA
CCCTCCTGCTGAAGATAAAATTGAGGTTAAAGATAAAGATTTATTTTCATATTTGTACAGTGATCGGCTTCAGTGATGGTTTTTGTGGGC
ATTTATTGTGTGTGTGTAAGAAATTTCATATGTATATATTAAGTAGGCCTCTGAGTATTGAATAATTGTTTTATGATTTTGATTTATATG
GTTTACATTTTCATTGTGTGGGCCATATTTCGTTTATACTGTTTATTTCTCTTCAAACCTTAATAATTATACCATAAAGTGTAATTTTTA

>In-frame_ENST00000339643_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(amino acids)=755AA_start in transcript=28_stop in transcript=2295
MSPFPLPLPFSGCLPGPLTLHSPGPAMSQKQEEENPAEETGEEKQDTQEKEGILPERAEEAKLKAKYPSLGQKPGGSDFLMKRLQKGDYK
SLHWSVLLCADEMQKYFDSGDYNMAKAKMKNKQLPSAGPDKNLVTGDHIPTPQDLPQRKSSLVTSKLAGEEQVSTLYQNINLVEPRLIQP
YEHVIKNFIREIRLQSTEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYETEVGDLQVTIKKLRK
LEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFLQSELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQIEILQTA
NRKLHDSNDGLRSALENSYSKFNRSLHINNISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDPLQRTNCEVDSLPESC
FDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDVPDIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKPISALSPQ
TDLVDDNAKSFSSQKAYKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQERFRSIAKSYFRKAD
GVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLA

--------------------------------------------------------------
>In-frame_ENST00000361532_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(transcript)=5257nt_BP=373nt
GGCGGGTGGTTGGAAAGACGGTGAATGGAAAGGGGATGGCTGGTGGTCTTGGGTGTGATGTGTGTTATTGGTTTGTAGAGGACACGCAGG
AGAAAGAAGGTATTCTGCCTGAGAGAGCTGAAGAGGCAAAGCTAAAGGCCAAATACCCAAGCCTAGGACAAAAGCCTGGAGGCTCCGACT
TCCTCATGAAGAGACTCCAGAAAGGGCAAAAGTACTTTGACTCAGGAGACTACAACATGGCCAAAGCCAAGATGAAGAATAAGCAGCTGC
CAAGTGCAGGACCAGACAAGAACCTGGTGACTGGTGATCACATCCCCACCCCACAGGATCTGCCCCAGAGAAAGTCCTCGCTCGTCACCA
GCAAGCTTGCGGGAGAAGAGCAAGTTAGTACCTTGTACCAAAACATCAACCTTGTGGAGCCAAGATTAATTCAGCCATATGAACATGTTA
TAAAGAACTTCATCCGTGAGATCAGACTTCAAAGCACAGAAATGGAAAATTTGGCCATTGCGGTGAAGAGAGCCCAGGACAAGGCAGCTA
TGCAGTTGAGTGAGTTGGAAGAGGAAATGGATCAGAGGATTCAGGCTGCAGAACATAAGACACGGAAAGACGAAAAACGCAAAGCTGAGG
AAGCCCTCAGTGACCTCAGACGTCAGTATGAAACTGAAGTAGGAGATCTGCAGGTGACCATTAAAAAGCTAAGAAAGCTCGAAGAACAAT
CAAAACGCGTAAGTCAAAAGGAAGATGTGGCTGCATTGAAAAAACAAATTTATGATTTATCAATGGAAAACCAGAAAGTTAAGAAAGACC
TTTTAGAAGCACAGACAAACATAGCCTTTCTTCAGAGTGAGTTAGATGCTTTGAAAAGTGATTATGCTGATCAGAGTCTGAATACTGAAA
GGGATCTGGAAATAATCCGAGCATACACAGAAGATCGAAATAGTCTTGAGAGGCAAATTGAAATACTCCAAACAGCTAACCGGAAGCTAC
ATGACAGTAATGATGGCCTTAGAAGTGCCCTTGAAAACAGTTATAGCAAGTTCAACAGATCTTTGCATATAAATAATATCTCACCAGGGA
ATACAATTTCTAGAAGCAGTCCCAAATTCATTGGTCATTCCCCTCAACCTCTAGGCTATGACAGGTCATCCCGCTCTTCCTATGTGGATG
AGGACTGTGACTCCCTGGCCCTCTGTGATCCTCTGCAGAGGACAAATTGTGAAGTTGACAGCCTGCCTGAAAGCTGCTTCGACAGCGGCT
TGTCTACCTTGAGAGATCCCAATGAGTATGACTCAGAAGTGGAATACAAGCACCAGAGGGGATTTCAGAGGTCACACGGGGTGCAGGAGA
GCTTTGGAGGTGATGCTTCAGACACAGATGTTCCTGACATAAGGGATGAAGAGACATTTGGTTTAGAAGATGTGGCTTCCGTCTTAGACT
GGAAGCCCCAAGGGTCTGTTAGTGAAGGCAGCATTGTTAGTTCATCAAGAAAGCCCATCTCAGCACTCTCGCCCCAGACAGACCTGGTAG
ATGACAACGCTAAATCTTTTAGCTCACAGAAGGCTTACAAGATTGTACTTGCTGGGGACGCTGCAGTGGGGAAGTCTAGTTTCCTCATGA
GACTTTGCAAGAATGAATTTCGAGAAAATATAAGCGCCACCCTGGGAGTTGATTTCCAAATGAAAACCCTCATTGTGGATGGAGAACGAA
CAGTTCTGCAGCTCTGGGATACAGCTGGTCAGGAGAGATTCAGAAGTATTGCCAAGTCTTACTTCAGAAAGGCAGATGGTGTTTTGCTGC
TGTATGATGTTACATGTGAGAAAAGCTTTCTTAACATACGAGAATGGGTAGATATGATTGAGGATGCAGCCCATGAGACTGTTCCCATTA
TGCTGGTAGGAAACAAGGCTGACATTCGTGACACTGCTGCTACAGAGGGACAAAAATGTGTCCCAGGGCACTTTGGAGAGAAACTGGCCA
TGACGTATGGGGCATTATTCTGTGAAACAAGTGCCAAAGATGGTTCTAACATAGTGGAGGCTGTTCTGCACCTTGCTCGAGAAGTGAAAA
AGAGAACTGACAAGGATGACAGCAGATCCATTACCAATCTAACCGGGACCAATTCCAAAAAGTCACCACAGATGAAGAATTGTTGCAATG
GCTAAATCCCAAACATCCTTGGCCTGTGAAGTCTTCATTTCCAGAATACTGAATTTGTGTGACTTATTTGGCTCTTAACAGAGTGGCACA
TCCTACTGACACTGTCCTATGGAGAGTTACAGTGCAGGAAACCTGAACCCAGCTCTCAGGTCCCTCTGGAACTTTGGCTCTTCTTTGTTT
TGTCTCAGTGAGTGATTTGGGCCCTCTGGCTAAATAGACTAGTCATGTCCTTACAGGTCTTAAAAGATAACATGTAAATGTTTTTAAAAT
GGTAAAAAAAAAGAAAAGAAAAGAAATCACATGCTCAGATCAAAGCTGTAGAGGAAACTGACATAATTAGATTCATGTGGTAGCTGAATT
AGGTTACCCACAAAGTCAGCATTTAAATATTTGATACTAAAGTTCTAGTAAGAAGGGATTCTCATCCTAGCTTTGCTGTTAACTGGCCTT
GTGACCTTGGACATGTCACAAGCCCATGTCGGATCTGTTTCTTCATCTGTAAAATGTGCAGCTTGCCCTCAAAGGCCTTGCAGCCCTTGG
CACCTCAGATTCTGTGGGAAGCAGTAGGACAGAGAGTGTGGTGGCCCACAGTTAATAATAGAACTATGGTTATTCCTGCTTTTTAATATT
GGAGTATTGATTTTTCTCACTTCTGAAATAAGGACAGAATTTGATTAAAAAATGGAAACAGAAATATCTATTTTTTATGTATAAAGAAAC
ATGTTTGAGACAAAAATAGTTGTATATAAAAGGATATTTCATAATCTCAGAATAGTTACAAAGCTCACTGCTTGAATTTGGTGTTAAAAA
TTCTAATGGAAACATGTAAAGCCACATACTACTGAAAGCACAATGCCCAGGAAAGTTGTCACTCTTCACTTAAGGGAGTGGTTGCCAGGG
GCTGAGAAAGGGAGGATGGGGAGTGACTGCTAATAGGTATGTGGTTTCTTTGGGCGATGATGAGAATGTTCTGGAATTGGAATAGTGGTG
ATAGTTGTATAACTGTTTGAATGTACTAGGAACCACTGAATTGTATACTTTGAAAGGGTGAATTTTATGGTTGTGAATTATCTCACTAAA
AAAAATGCTAGTACTTAGAGTGATGTAACATTTTGCAAAATTTTCATTTTCGTATCCCTGCTGATTTCAAACCTTCCCATGGTTTAGAAG
CATAACCTGTAATGTAATGCAAGTCCCCTAACTCCCTGGTTGCTAACATTAACTTCCTTAAGTAATAATCAATGAAAGAAATTCTATGCA
TGGTTTTGAAATAATATCCTTGAAAGAGGAATCACCATTAGGAAAGGTGAGTCAGGGTCCTTTGTTTAATGTGACTAGTGGCTCATCATC
ACCAGTGACCTGGTTGGGCCTACTCTCCTTCCAGAACCTGCATTGCTTCCCAGACCTCCCCACTGAGATGCCTCTAAGAGCCAAAGGAGT
CAACACTTGAGCCTAGGGTGGGCTACAACAAAAGATTCTAATTTACCTTGCTTCATCTAGGTCCAGGCCCCAAGTAGCTTGCTGAAGGAA
CTTAAAAAGTAGCTGTTATTTATTGTATTGTATAAGCTAAAAACATTTATTTTTGTTGAATCGAAACAATTCCATGTAGCAATCTTTTTT
CTGTTCACGGTGTTTGTGATAGAACCTTAAATTCCGCAAGCATCAGTTTTTTGAAAAAATGGGAATTGACCGGATAGTTACAGGCAAAGA
TTATAAATAGCTACAACATCATTTAACTTTTATAAACATGCCTTCTCTCTATTGAAGACATCTGATATTTTTGCTGGAAAGTTGGATCTA
TCCTCAGTAACTCTGCCATGAATTCCTGTTTCCTGGTTCCAGAAAAAGAAAAGATTACATTTCTGATCATAAAGAATGTCTTGCATATGG
GAAATTTTTCAAAATAAGGGGGGTATTATTTATGTGGCATGGGAAAACTTTTGCCATGGCTGTTTGTCTTAGTGGCATCTTTTGATGACA
TTGGATCAGATATATGTAGATGCTGATATATGGGACACATGTTTAGGTTTTGGTGCAGTTGCACAAAACTGTGTTAGTTTATATGTTACT
GTGTTGCCTTTATTTATTCTCTCCAAAGTGTCTCTTTATATTTGTTTTACAATCTGTGAAAGAGTATACCATAATACAGAAGTATTTTCA
TAGTCTTTACCTCTGGATTGTCCTGTCAGTATAGCCACGTTGATGAGATTACACCAGTGCCTTTGATGGTCAACCAATCATCTTTAAGTA
TTTGAGCCCTGATAAATATTTTGGTAACATAATCCAAATTAGAGACTTAGAGCTCTGGTTAGCAATCATGTTTAAAGAGAAGCTTCTTAA
AGCTCTGTATGCTGGGAGATTCATGATTATTACCAACGTTTTGATTTCATGAAGGTGTTCTCAAATTTAAAGCACATTTTCAGTAAGAAC
AAAAATATTTAATGTTTTTATCTTAGACTTGATACATTTGCATATTACTATGGAAGTTATTCACCTTGTCCCTGTTTTTCTTTAAGATAT
TTTAAAATCATAGTTATACTACAGTCCTTTTTTAAATGTATCCTGATACATTGTAAAATATTTTAATTTCATTGTGGAAAATAATGTTGG
ATAAGGAGATATTTTTCACTGTTAACTTTTAGCCCATGCATTTTCATAATTTATTTTTTTCACTTGCTGCTTTATATGACATATGTGACA
TTTGATTATTTAACACTTGATGTGATCTGCATAAACCCAAGTTGCACAACCCTCCTGCTGAAGATAAAATTGAGGTTAAAGATAAAGATT
TATTTTCATATTTGTACAGTGATCGGCTTCAGTGATGGTTTTTGTGGGCATTTATTGTGTGTGTGTAAGAAATTTCATATGTATATATTA
AGTAGGCCTCTGAGTATTGAATAATTGTTTTATGATTTTGATTTATATGGTTTACATTTTCATTGTGTGGGCCATATTTCGTTTATACTG
TTTATTTCTCTTCAAACCTTAATAATTATACCATAAAGTGTAATTTTTATAGCAATGCAAATGTCTAAGGAACTACAAATATTTTCTACG

>In-frame_ENST00000361532_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(amino acids)=709AA_start in transcript=35_stop in transcript=2164
MAGGLGCDVCYWFVEDTQEKEGILPERAEEAKLKAKYPSLGQKPGGSDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAGPDKNLVTG
DHIPTPQDLPQRKSSLVTSKLAGEEQVSTLYQNINLVEPRLIQPYEHVIKNFIREIRLQSTEMENLAIAVKRAQDKAAMQLSELEEEMDQ
RIQAAEHKTRKDEKRKAEEALSDLRRQYETEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFLQ
SELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQIEILQTANRKLHDSNDGLRSALENSYSKFNRSLHINNISPGNTISRSSPKFIG
HSPQPLGYDRSSRSSYVDEDCDSLALCDPLQRTNCEVDSLPESCFDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDVP
DIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKPISALSPQTDLVDDNAKSFSSQKAYKIVLAGDAAVGKSSFLMRLCKNEFRENIS
ATLGVDFQMKTLIVDGERTVLQLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT

--------------------------------------------------------------
>In-frame_ENST00000361631_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(transcript)=5293nt_BP=409nt
GAAAGACGGTGAATGGAAAGGGGATGGCTGGTGGTCTTGGGTGTGATGTGTGTTATTGGTTTGTAGAGGACACGCAGGAGAAAGAAGGTA
TTCTGCCTGAGAGAGCTGAAGAGGCAAAGCTAAAGGCCAAATACCCAAGCCTAGGACAAAAGCCTGGAGGCTCCGACTTCCTCATGAAGA
GACTCCAGAAAGGGGATTATAAATCATTACATTGGAGTGTGCTTCTCTGTGCGGATGAAATGCAAAAGTACTTTGACTCAGGAGACTACA
ACATGGCCAAAGCCAAGATGAAGAATAAGCAGCTGCCAAGTGCAGGACCAGACAAGAACCTGGTGACTGGTGATCACATCCCCACCCCAC
AGGATCTGCCCCAGAGAAAGTCCTCGCTCGTCACCAGCAAGCTTGCGGGAGAAGAGCAAGTTAGTACCTTGTACCAAAACATCAACCTTG
TGGAGCCAAGATTAATTCAGCCATATGAACATGTTATAAAGAACTTCATCCGTGAGATCAGACTTCAAAGCACAGAAATGGAAAATTTGG
CCATTGCGGTGAAGAGAGCCCAGGACAAGGCAGCTATGCAGTTGAGTGAGTTGGAAGAGGAAATGGATCAGAGGATTCAGGCTGCAGAAC
ATAAGACACGGAAAGACGAAAAACGCAAAGCTGAGGAAGCCCTCAGTGACCTCAGACGTCAGTATGAAACTGAAGTAGGAGATCTGCAGG
TGACCATTAAAAAGCTAAGAAAGCTCGAAGAACAATCAAAACGCGTAAGTCAAAAGGAAGATGTGGCTGCATTGAAAAAACAAATTTATG
ATTTATCAATGGAAAACCAGAAAGTTAAGAAAGACCTTTTAGAAGCACAGACAAACATAGCCTTTCTTCAGAGTGAGTTAGATGCTTTGA
AAAGTGATTATGCTGATCAGAGTCTGAATACTGAAAGGGATCTGGAAATAATCCGAGCATACACAGAAGATCGAAATAGTCTTGAGAGGC
AAATTGAAATACTCCAAACAGCTAACCGGAAGCTACATGACAGTAATGATGGCCTTAGAAGTGCCCTTGAAAACAGTTATAGCAAGTTCA
ACAGATCTTTGCATATAAATAATATCTCACCAGGGAATACAATTTCTAGAAGCAGTCCCAAATTCATTGGTCATTCCCCTCAACCTCTAG
GCTATGACAGGTCATCCCGCTCTTCCTATGTGGATGAGGACTGTGACTCCCTGGCCCTCTGTGATCCTCTGCAGAGGACAAATTGTGAAG
TTGACAGCCTGCCTGAAAGCTGCTTCGACAGCGGCTTGTCTACCTTGAGAGATCCCAATGAGTATGACTCAGAAGTGGAATACAAGCACC
AGAGGGGATTTCAGAGGTCACACGGGGTGCAGGAGAGCTTTGGAGGTGATGCTTCAGACACAGATGTTCCTGACATAAGGGATGAAGAGA
CATTTGGTTTAGAAGATGTGGCTTCCGTCTTAGACTGGAAGCCCCAAGGGTCTGTTAGTGAAGGCAGCATTGTTAGTTCATCAAGAAAGC
CCATCTCAGCACTCTCGCCCCAGACAGACCTGGTAGATGACAACGCTAAATCTTTTAGCTCACAGAAGGCTTACAAGATTGTACTTGCTG
GGGACGCTGCAGTGGGGAAGTCTAGTTTCCTCATGAGACTTTGCAAGAATGAATTTCGAGAAAATATAAGCGCCACCCTGGGAGTTGATT
TCCAAATGAAAACCCTCATTGTGGATGGAGAACGAACAGTTCTGCAGCTCTGGGATACAGCTGGTCAGGAGAGATTCAGAAGTATTGCCA
AGTCTTACTTCAGAAAGGCAGATGGTGTTTTGCTGCTGTATGATGTTACATGTGAGAAAAGCTTTCTTAACATACGAGAATGGGTAGATA
TGATTGAGGATGCAGCCCATGAGACTGTTCCCATTATGCTGGTAGGAAACAAGGCTGACATTCGTGACACTGCTGCTACAGAGGGACAAA
AATGTGTCCCAGGGCACTTTGGAGAGAAACTGGCCATGACGTATGGGGCATTATTCTGTGAAACAAGTGCCAAAGATGGTTCTAACATAG
TGGAGGCTGTTCTGCACCTTGCTCGAGAAGTGAAAAAGAGAACTGACAAGGATGACAGCAGATCCATTACCAATCTAACCGGGACCAATT
CCAAAAAGTCACCACAGATGAAGAATTGTTGCAATGGCTAAATCCCAAACATCCTTGGCCTGTGAAGTCTTCATTTCCAGAATACTGAAT
TTGTGTGACTTATTTGGCTCTTAACAGAGTGGCACATCCTACTGACACTGTCCTATGGAGAGTTACAGTGCAGGAAACCTGAACCCAGCT
CTCAGGTCCCTCTGGAACTTTGGCTCTTCTTTGTTTTGTCTCAGTGAGTGATTTGGGCCCTCTGGCTAAATAGACTAGTCATGTCCTTAC
AGGTCTTAAAAGATAACATGTAAATGTTTTTAAAATGGTAAAAAAAAAGAAAAGAAAAGAAATCACATGCTCAGATCAAAGCTGTAGAGG
AAACTGACATAATTAGATTCATGTGGTAGCTGAATTAGGTTACCCACAAAGTCAGCATTTAAATATTTGATACTAAAGTTCTAGTAAGAA
GGGATTCTCATCCTAGCTTTGCTGTTAACTGGCCTTGTGACCTTGGACATGTCACAAGCCCATGTCGGATCTGTTTCTTCATCTGTAAAA
TGTGCAGCTTGCCCTCAAAGGCCTTGCAGCCCTTGGCACCTCAGATTCTGTGGGAAGCAGTAGGACAGAGAGTGTGGTGGCCCACAGTTA
ATAATAGAACTATGGTTATTCCTGCTTTTTAATATTGGAGTATTGATTTTTCTCACTTCTGAAATAAGGACAGAATTTGATTAAAAAATG
GAAACAGAAATATCTATTTTTTATGTATAAAGAAACATGTTTGAGACAAAAATAGTTGTATATAAAAGGATATTTCATAATCTCAGAATA
GTTACAAAGCTCACTGCTTGAATTTGGTGTTAAAAATTCTAATGGAAACATGTAAAGCCACATACTACTGAAAGCACAATGCCCAGGAAA
GTTGTCACTCTTCACTTAAGGGAGTGGTTGCCAGGGGCTGAGAAAGGGAGGATGGGGAGTGACTGCTAATAGGTATGTGGTTTCTTTGGG
CGATGATGAGAATGTTCTGGAATTGGAATAGTGGTGATAGTTGTATAACTGTTTGAATGTACTAGGAACCACTGAATTGTATACTTTGAA
AGGGTGAATTTTATGGTTGTGAATTATCTCACTAAAAAAAATGCTAGTACTTAGAGTGATGTAACATTTTGCAAAATTTTCATTTTCGTA
TCCCTGCTGATTTCAAACCTTCCCATGGTTTAGAAGCATAACCTGTAATGTAATGCAAGTCCCCTAACTCCCTGGTTGCTAACATTAACT
TCCTTAAGTAATAATCAATGAAAGAAATTCTATGCATGGTTTTGAAATAATATCCTTGAAAGAGGAATCACCATTAGGAAAGGTGAGTCA
GGGTCCTTTGTTTAATGTGACTAGTGGCTCATCATCACCAGTGACCTGGTTGGGCCTACTCTCCTTCCAGAACCTGCATTGCTTCCCAGA
CCTCCCCACTGAGATGCCTCTAAGAGCCAAAGGAGTCAACACTTGAGCCTAGGGTGGGCTACAACAAAAGATTCTAATTTACCTTGCTTC
ATCTAGGTCCAGGCCCCAAGTAGCTTGCTGAAGGAACTTAAAAAGTAGCTGTTATTTATTGTATTGTATAAGCTAAAAACATTTATTTTT
GTTGAATCGAAACAATTCCATGTAGCAATCTTTTTTCTGTTCACGGTGTTTGTGATAGAACCTTAAATTCCGCAAGCATCAGTTTTTTGA
AAAAATGGGAATTGACCGGATAGTTACAGGCAAAGATTATAAATAGCTACAACATCATTTAACTTTTATAAACATGCCTTCTCTCTATTG
AAGACATCTGATATTTTTGCTGGAAAGTTGGATCTATCCTCAGTAACTCTGCCATGAATTCCTGTTTCCTGGTTCCAGAAAAAGAAAAGA
TTACATTTCTGATCATAAAGAATGTCTTGCATATGGGAAATTTTTCAAAATAAGGGGGGTATTATTTATGTGGCATGGGAAAACTTTTGC
CATGGCTGTTTGTCTTAGTGGCATCTTTTGATGACATTGGATCAGATATATGTAGATGCTGATATATGGGACACATGTTTAGGTTTTGGT
GCAGTTGCACAAAACTGTGTTAGTTTATATGTTACTGTGTTGCCTTTATTTATTCTCTCCAAAGTGTCTCTTTATATTTGTTTTACAATC
TGTGAAAGAGTATACCATAATACAGAAGTATTTTCATAGTCTTTACCTCTGGATTGTCCTGTCAGTATAGCCACGTTGATGAGATTACAC
CAGTGCCTTTGATGGTCAACCAATCATCTTTAAGTATTTGAGCCCTGATAAATATTTTGGTAACATAATCCAAATTAGAGACTTAGAGCT
CTGGTTAGCAATCATGTTTAAAGAGAAGCTTCTTAAAGCTCTGTATGCTGGGAGATTCATGATTATTACCAACGTTTTGATTTCATGAAG
GTGTTCTCAAATTTAAAGCACATTTTCAGTAAGAACAAAAATATTTAATGTTTTTATCTTAGACTTGATACATTTGCATATTACTATGGA
AGTTATTCACCTTGTCCCTGTTTTTCTTTAAGATATTTTAAAATCATAGTTATACTACAGTCCTTTTTTAAATGTATCCTGATACATTGT
AAAATATTTTAATTTCATTGTGGAAAATAATGTTGGATAAGGAGATATTTTTCACTGTTAACTTTTAGCCCATGCATTTTCATAATTTAT
TTTTTTCACTTGCTGCTTTATATGACATATGTGACATTTGATTATTTAACACTTGATGTGATCTGCATAAACCCAAGTTGCACAACCCTC
CTGCTGAAGATAAAATTGAGGTTAAAGATAAAGATTTATTTTCATATTTGTACAGTGATCGGCTTCAGTGATGGTTTTTGTGGGCATTTA
TTGTGTGTGTGTAAGAAATTTCATATGTATATATTAAGTAGGCCTCTGAGTATTGAATAATTGTTTTATGATTTTGATTTATATGGTTTA
CATTTTCATTGTGTGGGCCATATTTCGTTTATACTGTTTATTTCTCTTCAAACCTTAATAATTATACCATAAAGTGTAATTTTTATAGCA

>In-frame_ENST00000361631_ENST00000376447_DB237062_ENSA_chr1_150598118_-_RASEF_chr9_85640837_length(amino acids)=725AA_start in transcript=23_stop in transcript=2200
MAGGLGCDVCYWFVEDTQEKEGILPERAEEAKLKAKYPSLGQKPGGSDFLMKRLQKGDYKSLHWSVLLCADEMQKYFDSGDYNMAKAKMK
NKQLPSAGPDKNLVTGDHIPTPQDLPQRKSSLVTSKLAGEEQVSTLYQNINLVEPRLIQPYEHVIKNFIREIRLQSTEMENLAIAVKRAQ
DKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYETEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQK
VKKDLLEAQTNIAFLQSELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQIEILQTANRKLHDSNDGLRSALENSYSKFNRSLHINN
ISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDPLQRTNCEVDSLPESCFDSGLSTLRDPNEYDSEVEYKHQRGFQRSH
GVQESFGGDASDTDVPDIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKPISALSPQTDLVDDNAKSFSSQKAYKIVLAGDAAVGKS
SFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHE
TVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSITNLTGTNSKKSPQMK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ENSA-RASEF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ENSA-RASEF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ENSA-RASEF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneENSAC0151744Myocardial Ischemia1CTD_human