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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EPC1-ARHGAP12 (FusionGDB2 ID:26853)

Fusion Gene Summary for EPC1-ARHGAP12

check button Fusion gene summary
Fusion gene informationFusion gene name: EPC1-ARHGAP12
Fusion gene ID: 26853
HgeneTgene
Gene symbol

EPC1

ARHGAP12

Gene ID

80314

94134

Gene nameenhancer of polycomb homolog 1Rho GTPase activating protein 12
SynonymsEpl1-
Cytomap

10p11.22

10p11.22

Type of geneprotein-codingprotein-coding
Descriptionenhancer of polycomb homolog 1rho GTPase-activating protein 12rho-type GTPase-activating protein 12
Modification date2020031320200313
UniProtAcc.

Q8IWW6

Ensembl transtripts involved in fusion geneENST00000375110, ENST00000319778, 
ENST00000263062, ENST00000480402, 
ENST00000311380, ENST00000375250, 
ENST00000492028, ENST00000344936, 
ENST00000396144, ENST00000375245, 
Fusion gene scores* DoF score17 X 14 X 8=190412 X 14 X 5=840
# samples 2015
** MAII scorelog2(20/1904*10)=-3.25096157353322
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/840*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EPC1 [Title/Abstract] AND ARHGAP12 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEPC1(32635690)-ARHGAP12(32120728), # samples:1
EPC1(32667419)-ARHGAP12(32199491), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneEPC1

GO:0000122

negative regulation of transcription by RNA polymerase II

10976108

HgeneEPC1

GO:0043967

histone H4 acetylation

14966270

HgeneEPC1

GO:0043968

histone H2A acetylation

14966270

HgeneEPC1

GO:0045814

negative regulation of gene expression, epigenetic

10976108

HgeneEPC1

GO:0045892

negative regulation of transcription, DNA-templated

10976108

HgeneEPC1

GO:0045944

positive regulation of transcription by RNA polymerase II

10976108


check buttonFusion gene breakpoints across EPC1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ARHGAP12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-HC-8260EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
ChimerDB4STADTCGA-BR-8080-01AEPC1chr10

32667419

-ARHGAP12chr10

32199491

-


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Fusion Gene ORF analysis for EPC1-ARHGAP12

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000375110ENST00000311380EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
intron-3CDSENST00000375110ENST00000375250EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
intron-intronENST00000375110ENST00000492028EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
intron-intronENST00000375110ENST00000344936EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
intron-intronENST00000375110ENST00000396144EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
intron-intronENST00000375110ENST00000375245EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
In-frameENST00000319778ENST00000311380EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
In-frameENST00000319778ENST00000375250EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5CDS-intronENST00000319778ENST00000492028EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5CDS-intronENST00000319778ENST00000344936EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5CDS-intronENST00000319778ENST00000396144EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5CDS-intronENST00000319778ENST00000375245EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
In-frameENST00000263062ENST00000311380EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
In-frameENST00000263062ENST00000375250EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5CDS-intronENST00000263062ENST00000492028EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5CDS-intronENST00000263062ENST00000344936EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5CDS-intronENST00000263062ENST00000396144EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5CDS-intronENST00000263062ENST00000375245EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5UTR-3CDSENST00000480402ENST00000311380EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5UTR-3CDSENST00000480402ENST00000375250EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5UTR-intronENST00000480402ENST00000492028EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5UTR-intronENST00000480402ENST00000344936EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5UTR-intronENST00000480402ENST00000396144EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5UTR-intronENST00000480402ENST00000375245EPC1chr10

32635690

-ARHGAP12chr10

32120728

-
5CDS-intronENST00000375110ENST00000311380EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
5CDS-5UTRENST00000375110ENST00000375250EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
5CDS-intronENST00000375110ENST00000492028EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
5CDS-5UTRENST00000375110ENST00000344936EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
5CDS-5UTRENST00000375110ENST00000396144EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
5CDS-5UTRENST00000375110ENST00000375245EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-intronENST00000319778ENST00000311380EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000319778ENST00000375250EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-intronENST00000319778ENST00000492028EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000319778ENST00000344936EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000319778ENST00000396144EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000319778ENST00000375245EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-intronENST00000263062ENST00000311380EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000263062ENST00000375250EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-intronENST00000263062ENST00000492028EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000263062ENST00000344936EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000263062ENST00000396144EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000263062ENST00000375245EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-intronENST00000480402ENST00000311380EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000480402ENST00000375250EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-intronENST00000480402ENST00000492028EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000480402ENST00000344936EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000480402ENST00000396144EPC1chr10

32667419

-ARHGAP12chr10

32199491

-
intron-5UTRENST00000480402ENST00000375245EPC1chr10

32667419

-ARHGAP12chr10

32199491

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000319778EPC1chr1032635690-ENST00000311380ARHGAP12chr1032120728-38324563031610435
ENST00000319778EPC1chr1032635690-ENST00000375250ARHGAP12chr1032120728-38324563031610435
ENST00000263062EPC1chr1032635690-ENST00000311380ARHGAP12chr1032120728-37994232701577435
ENST00000263062EPC1chr1032635690-ENST00000375250ARHGAP12chr1032120728-37994232701577435

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000319778ENST00000311380EPC1chr1032635690-ARHGAP12chr1032120728-0.0001771260.9998229
ENST00000319778ENST00000375250EPC1chr1032635690-ARHGAP12chr1032120728-0.0001771260.9998229
ENST00000263062ENST00000311380EPC1chr1032635690-ARHGAP12chr1032120728-0.000181180.99981886
ENST00000263062ENST00000375250EPC1chr1032635690-ARHGAP12chr1032120728-0.000181180.99981886

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Fusion Genomic Features for EPC1-ARHGAP12


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for EPC1-ARHGAP12


check button Go to

FGviewer for the breakpoints of chr10:32635690-chr10:32120728

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ARHGAP12

Q8IWW6

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000311380416463_575410.0795.0DomainPH
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000311380416656_844410.0795.0DomainRho-GAP
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000344936820463_575462.0847.0DomainPH
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000344936820656_844462.0847.0DomainRho-GAP
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000375245618463_575410.0795.0DomainPH
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000375245618656_844410.0795.0DomainRho-GAP
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000375250618463_575432.0817.0DomainPH
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000375250618656_844432.0817.0DomainRho-GAP
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000396144719463_575457.0842.0DomainPH
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000396144719656_844457.0842.0DomainRho-GAP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARHGAP12chr10:32635690chr10:32120728ENST0000031138041612_74410.0795.0DomainSH3
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000311380416265_298410.0795.0DomainWW 1
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000311380416358_391410.0795.0DomainWW 2
TgeneARHGAP12chr10:32635690chr10:32120728ENST0000034493682012_74462.0847.0DomainSH3
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000344936820265_298462.0847.0DomainWW 1
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000344936820358_391462.0847.0DomainWW 2
TgeneARHGAP12chr10:32635690chr10:32120728ENST0000037524561812_74410.0795.0DomainSH3
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000375245618265_298410.0795.0DomainWW 1
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000375245618358_391410.0795.0DomainWW 2
TgeneARHGAP12chr10:32635690chr10:32120728ENST0000037525061812_74432.0817.0DomainSH3
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000375250618265_298432.0817.0DomainWW 1
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000375250618358_391432.0817.0DomainWW 2
TgeneARHGAP12chr10:32635690chr10:32120728ENST0000039614471912_74457.0842.0DomainSH3
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000396144719265_298457.0842.0DomainWW 1
TgeneARHGAP12chr10:32635690chr10:32120728ENST00000396144719358_391457.0842.0DomainWW 2


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Fusion Gene Sequence for EPC1-ARHGAP12


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000319778_ENST00000311380_TCGA-HC-8260_EPC1_chr10_32635690_-_ARHGAP12_chr10_32120728_length(transcript)=3832nt_BP=456nt
GCGTGCCCGCGCCGCTGCGCGATGCAGTGTGGGGAATGGCTGGGGTTGGCTGAAGAGCGCACAGTGGAGTTTTAATGTCCGCCATGTTGG
CCATGGCGTATTGAAGAGAGCGAGCGAGAGAGGAGCGGAGCGGCACAGCCTCCCACCCTCCCGGCTGGTGTTAGTGCCCGGACGGCGGGC
TCTGCGCTCCGCCCCTCAAGTCCCCGGCAGCGGTTGGCGAGTGGGGACCGAACCCCCGGTTCTCCATGATCCCGCTGGCCGGGGCCGTTT
CCCCAGAGCGGAGAGGTATCTGCTGCGCCTGAGATGAGTAAACTGTCGTTTCGGGCGCGGGCGCTAGACGCCTCGAAGCCGCTGCCGGTT
TTCCGCTGTGAGGATCTGCCCGACCTGCACGAATACGCCTCGATAAACAGGGCCGTGCCGCAGATGCCCACCGGAATGGAGAAGGAAGAG
GAGTCGGATCAAGAGAAATATGGATTATTAAATGTAACAAAAATTGCTGAAAATGGGAAAAAGGTTCGAAAGAACTGGTTGTCTTCTTGG
GCGGTGTTGCAGGGTTCATCTTTACTTTTTACCAAAACTCAAGGAAGTAGCACAAGTTGGTTTGGCAGTAATCAGTCCAAACCAGAGTTC
ACAGTGGACCTCAAGGGGGCAACAATTGAGATGGCTTCAAAGGATAAATCCAGCAAAAAGAATGTATTTGAGCTGAAAACTCGTCAAGGA
ACAGAACTGCTAATTCAGTCTGACAATGACACTGTTATTAATGATTGGTTTAAAGTTCTTAGTAGTACAATCAATAATCAGGCAGTAGAA
ACTGATGAAGGAATTGAAGAGGAGATACCGGATTCACCAGGAATAGAAAAGCATGATAAAGAAAAGGAACAAAAGGATCCCAAAAAGCTT
CGTTCCTTTAAAGTATCTAGCATAGATTCTTCAGAACAGAAAAAAACCAAGAAAAACTTAAAGAAGTTTCTTACACGACGCCCCACTTTG
CAAGCTGTTCGTGAAAAAGGTTATATTAAAGATCAGGTATTTGGATCCAATCTCGCTAATCTGTGTCAGAGAGAGAATGGCACAGTACCA
AAGTTTGTGAAGTTATGTATTGAACATGTTGAAGAACATGGTTTGGATATTGATGGGATATACAGAGTAAGTGGCAACCTCGCAGTGATC
CAGAAACTAAGGTTTGCAGTCAATCATGATGAGAAATTGGACTTGAATGACAGTAAATGGGAAGATATTCATGTCATTACTGGAGCCCTC
AAAATGTTTTTTCGAGAATTACCAGAACCTCTTTTTACATTTAATCATTTTAATGATTTTGTTAATGCAATTAAGCAAGAACCAAGACAG
CGAGTCGCTGCTGTTAAGGACCTAATCAGACAGTTGCCAAAGCCAAACCAAGACACAATGCAGATTCTTTTCCGACATCTCAGAAGAGTT
ATAGAAAATGGAGAGAAAAATCGAATGACCTATCAGAGTATAGCAATTGTTTTTGGTCCCACTCTATTAAAACCAGAAAAAGAGACTGGT
AATATAGCAGTTCATACTGTGTACCAGAATCAGATTGTAGAATTAATTCTTCTGGAACTGAGTTCCATCTTCGGACGTTGATTCTTACTG
AAGACAACCTGTGGAATAGAAGCTGGATTCCATCAGATTTCAAATGTTTATACACAATGTATTTTATTTTTTGGACCAAGCAGTGACTCT
TTGATTTTGCACTTTTTTTTTGAGGGATCAGAAGGGAAGGGGAGAGTCGAGATGTGTGTTAGGCCCTCATATTTGCTGCTTTGTTGCAAG
TTGATATAACTGCGTGTAATTATGAATTCATTTTATCCTGAATGTTTGCATTTCATACTCTGAATTTCAGTAAAAATCAAAACTTAAAAT
TCTAACCAGTCATATACACTGGATAATTTGGTAAGAAAACTGTATTTTTTTTCCCTGAAATTGGATAATGTACTTTCTTCTCAAGATTCA
TGACTTGATAGAACAATACTTTCAGTTATGTTGCAAAGGCTCTTGGGCATTTTAAACAAAATGAAGTATATCCATTTTGAAACCTGTGTA
TTTCTTTTTCGGGGTTTCTGCATGCAGTGGCAGTCTTAAGTGCCAAAATTCATTATAACCCCAAAATAACCCCTTGATGAAGGCTTGCTG
TCTTTTACTGTGTTACACAGCATCCTTACTGGATATCTTAGTTGCTTGTTTGGGCAGCACACTAATATTACTTAAAACACTGTGATATAC
TGGAGTTTTAGTTAGCGGAAGTCAGTTCAGGGCATTTTAGGGCTGTCTTGCTATACTGAATTGTAGCTAACAATCCTAATTATATCTAGT
ACCATACTGAGTTATTGGTATGACCCTGTGGAAACACACATTATTTTATGTAAATATAGGCTAAAGACTTAATGTCCTTTAGCTTGTGTA
TATAATTGTGTTGTATAGTCTCAGAGTACATTCTAACCCTACATTTCTAATCATTGTTATTGGTAATCTTTTCTGTGAATATTAGGTTTC
CTCCAGAAATAGTCCGTTATTTGGGAAAGTTAACTGTGTGCACTTTTAGATATTAACTACATTTACAGGCAAATCACTGTAATGAGAATG
GTACTGGAAAAATACTGAATAGACTTGCTAAATGGCACATGCACTACAAGAGGAACCTTTTGGGTTATTTAATATGTACAGAAAACATTA
GAAAAAATTTATTACAGAATTCTAATTCCAGTATGAATAGTGGAAACCCATCTGTAAATTAGATGGATGTTGGATGGAAAATGACATTGC
TAAATTTGAGAATTTCTTTTTACCTACTAATGTAGATTGCTTTGTATAATAAAACACAGGGTTTGGAAGGTTTTGTTACAGGGAGCATGG
TCTGTTGAAGATTTTTAAAATGTATTTTTCTAGATTAACTTCTGTACATGAAATGTCTAATAAAACTATAAGAGGTTTAGAGATTTTTCC
ATTGGAAATGTGCATTTTGGTTTCTAATTTTTTTGTTTTTTCATTTACTGGCATACTGTTATACCTCATTTTTAAAAATCAACTGAATCC
AATATTTCCTGTGGCAAATAACACTTTCCTCATTTCATACCTTTTCTCCTCTCTTCCATGCCAACATTTCTCCACCCACAACGTACACTT
TTTATTTCTCCATCAATATTTGAAAGCGAGTGATTTGTGACCAGGATTTTTTTTTCTTAGGGTTGCATTTATAATTTACAGATTGCCTTC
CTTGGGAACAAGTATTTTTTTGTATGATCTGTCTAAAAACCTCTCACCTGAATTTTGTGGTAGAAAGTCTGTATTTGTTGTTGTGAGCGT
GTTAAATTGATAACAAACCAAACTACTTGATAGCTAAAGCAGATTGTTTCGGGTGGGGAGAAAAAGCCCTAAATCAGAATGTTTATATTT
GCCTAAAGATGTCCTTAATAATACAATATGCTTTAGATCTTGCTTATTTAGTGATTGTATACCAGGAAAACAATTAGACTCAAATCAGTG
ATGTTCTTGTTCTTGGTGTTCATGAACATATATCAAAGATTAAAATTGTCCTGTGTTTCTTGTTTCAAGGTACGTGTGTGTGTGTGTGTG
TGTGTGTGTGTGTGTGTGTGAAGTCTTAAATGTTTTATTAGTCTACAGCTAATCAGTTTATTGTAATATTGTATGTACAGTGAGATTAAT
GTCTTGCGTTTTCATCCTTTGTGAATTAAAAATTCTCACTTGTTTTGTAATAACAAAGCTAGTAATATTTTCCTGTCTTGACAGCTTGGT

>In-frame_ENST00000319778_ENST00000311380_TCGA-HC-8260_EPC1_chr10_32635690_-_ARHGAP12_chr10_32120728_length(amino acids)=435AA_start in transcript=303_stop in transcript=1610
MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESDQEKYGLLNVTKIAENGKKVRKNWLSSWAVLQGSSLLFT
KTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPD
SPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVE
EHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQ

--------------------------------------------------------------
>In-frame_ENST00000319778_ENST00000375250_TCGA-HC-8260_EPC1_chr10_32635690_-_ARHGAP12_chr10_32120728_length(transcript)=3832nt_BP=456nt
GCGTGCCCGCGCCGCTGCGCGATGCAGTGTGGGGAATGGCTGGGGTTGGCTGAAGAGCGCACAGTGGAGTTTTAATGTCCGCCATGTTGG
CCATGGCGTATTGAAGAGAGCGAGCGAGAGAGGAGCGGAGCGGCACAGCCTCCCACCCTCCCGGCTGGTGTTAGTGCCCGGACGGCGGGC
TCTGCGCTCCGCCCCTCAAGTCCCCGGCAGCGGTTGGCGAGTGGGGACCGAACCCCCGGTTCTCCATGATCCCGCTGGCCGGGGCCGTTT
CCCCAGAGCGGAGAGGTATCTGCTGCGCCTGAGATGAGTAAACTGTCGTTTCGGGCGCGGGCGCTAGACGCCTCGAAGCCGCTGCCGGTT
TTCCGCTGTGAGGATCTGCCCGACCTGCACGAATACGCCTCGATAAACAGGGCCGTGCCGCAGATGCCCACCGGAATGGAGAAGGAAGAG
GAGTCGGATCAAGAGAAATATGGATTATTAAATGTAACAAAAATTGCTGAAAATGGGAAAAAGGTTCGAAAGAACTGGTTGTCTTCTTGG
GCGGTGTTGCAGGGTTCATCTTTACTTTTTACCAAAACTCAAGGAAGTAGCACAAGTTGGTTTGGCAGTAATCAGTCCAAACCAGAGTTC
ACAGTGGACCTCAAGGGGGCAACAATTGAGATGGCTTCAAAGGATAAATCCAGCAAAAAGAATGTATTTGAGCTGAAAACTCGTCAAGGA
ACAGAACTGCTAATTCAGTCTGACAATGACACTGTTATTAATGATTGGTTTAAAGTTCTTAGTAGTACAATCAATAATCAGGCAGTAGAA
ACTGATGAAGGAATTGAAGAGGAGATACCGGATTCACCAGGAATAGAAAAGCATGATAAAGAAAAGGAACAAAAGGATCCCAAAAAGCTT
CGTTCCTTTAAAGTATCTAGCATAGATTCTTCAGAACAGAAAAAAACCAAGAAAAACTTAAAGAAGTTTCTTACACGACGCCCCACTTTG
CAAGCTGTTCGTGAAAAAGGTTATATTAAAGATCAGGTATTTGGATCCAATCTCGCTAATCTGTGTCAGAGAGAGAATGGCACAGTACCA
AAGTTTGTGAAGTTATGTATTGAACATGTTGAAGAACATGGTTTGGATATTGATGGGATATACAGAGTAAGTGGCAACCTCGCAGTGATC
CAGAAACTAAGGTTTGCAGTCAATCATGATGAGAAATTGGACTTGAATGACAGTAAATGGGAAGATATTCATGTCATTACTGGAGCCCTC
AAAATGTTTTTTCGAGAATTACCAGAACCTCTTTTTACATTTAATCATTTTAATGATTTTGTTAATGCAATTAAGCAAGAACCAAGACAG
CGAGTCGCTGCTGTTAAGGACCTAATCAGACAGTTGCCAAAGCCAAACCAAGACACAATGCAGATTCTTTTCCGACATCTCAGAAGAGTT
ATAGAAAATGGAGAGAAAAATCGAATGACCTATCAGAGTATAGCAATTGTTTTTGGTCCCACTCTATTAAAACCAGAAAAAGAGACTGGT
AATATAGCAGTTCATACTGTGTACCAGAATCAGATTGTAGAATTAATTCTTCTGGAACTGAGTTCCATCTTCGGACGTTGATTCTTACTG
AAGACAACCTGTGGAATAGAAGCTGGATTCCATCAGATTTCAAATGTTTATACACAATGTATTTTATTTTTTGGACCAAGCAGTGACTCT
TTGATTTTGCACTTTTTTTTTGAGGGATCAGAAGGGAAGGGGAGAGTCGAGATGTGTGTTAGGCCCTCATATTTGCTGCTTTGTTGCAAG
TTGATATAACTGCGTGTAATTATGAATTCATTTTATCCTGAATGTTTGCATTTCATACTCTGAATTTCAGTAAAAATCAAAACTTAAAAT
TCTAACCAGTCATATACACTGGATAATTTGGTAAGAAAACTGTATTTTTTTTCCCTGAAATTGGATAATGTACTTTCTTCTCAAGATTCA
TGACTTGATAGAACAATACTTTCAGTTATGTTGCAAAGGCTCTTGGGCATTTTAAACAAAATGAAGTATATCCATTTTGAAACCTGTGTA
TTTCTTTTTCGGGGTTTCTGCATGCAGTGGCAGTCTTAAGTGCCAAAATTCATTATAACCCCAAAATAACCCCTTGATGAAGGCTTGCTG
TCTTTTACTGTGTTACACAGCATCCTTACTGGATATCTTAGTTGCTTGTTTGGGCAGCACACTAATATTACTTAAAACACTGTGATATAC
TGGAGTTTTAGTTAGCGGAAGTCAGTTCAGGGCATTTTAGGGCTGTCTTGCTATACTGAATTGTAGCTAACAATCCTAATTATATCTAGT
ACCATACTGAGTTATTGGTATGACCCTGTGGAAACACACATTATTTTATGTAAATATAGGCTAAAGACTTAATGTCCTTTAGCTTGTGTA
TATAATTGTGTTGTATAGTCTCAGAGTACATTCTAACCCTACATTTCTAATCATTGTTATTGGTAATCTTTTCTGTGAATATTAGGTTTC
CTCCAGAAATAGTCCGTTATTTGGGAAAGTTAACTGTGTGCACTTTTAGATATTAACTACATTTACAGGCAAATCACTGTAATGAGAATG
GTACTGGAAAAATACTGAATAGACTTGCTAAATGGCACATGCACTACAAGAGGAACCTTTTGGGTTATTTAATATGTACAGAAAACATTA
GAAAAAATTTATTACAGAATTCTAATTCCAGTATGAATAGTGGAAACCCATCTGTAAATTAGATGGATGTTGGATGGAAAATGACATTGC
TAAATTTGAGAATTTCTTTTTACCTACTAATGTAGATTGCTTTGTATAATAAAACACAGGGTTTGGAAGGTTTTGTTACAGGGAGCATGG
TCTGTTGAAGATTTTTAAAATGTATTTTTCTAGATTAACTTCTGTACATGAAATGTCTAATAAAACTATAAGAGGTTTAGAGATTTTTCC
ATTGGAAATGTGCATTTTGGTTTCTAATTTTTTTGTTTTTTCATTTACTGGCATACTGTTATACCTCATTTTTAAAAATCAACTGAATCC
AATATTTCCTGTGGCAAATAACACTTTCCTCATTTCATACCTTTTCTCCTCTCTTCCATGCCAACATTTCTCCACCCACAACGTACACTT
TTTATTTCTCCATCAATATTTGAAAGCGAGTGATTTGTGACCAGGATTTTTTTTTCTTAGGGTTGCATTTATAATTTACAGATTGCCTTC
CTTGGGAACAAGTATTTTTTTGTATGATCTGTCTAAAAACCTCTCACCTGAATTTTGTGGTAGAAAGTCTGTATTTGTTGTTGTGAGCGT
GTTAAATTGATAACAAACCAAACTACTTGATAGCTAAAGCAGATTGTTTCGGGTGGGGAGAAAAAGCCCTAAATCAGAATGTTTATATTT
GCCTAAAGATGTCCTTAATAATACAATATGCTTTAGATCTTGCTTATTTAGTGATTGTATACCAGGAAAACAATTAGACTCAAATCAGTG
ATGTTCTTGTTCTTGGTGTTCATGAACATATATCAAAGATTAAAATTGTCCTGTGTTTCTTGTTTCAAGGTACGTGTGTGTGTGTGTGTG
TGTGTGTGTGTGTGTGTGTGAAGTCTTAAATGTTTTATTAGTCTACAGCTAATCAGTTTATTGTAATATTGTATGTACAGTGAGATTAAT
GTCTTGCGTTTTCATCCTTTGTGAATTAAAAATTCTCACTTGTTTTGTAATAACAAAGCTAGTAATATTTTCCTGTCTTGACAGCTTGGT

>In-frame_ENST00000319778_ENST00000375250_TCGA-HC-8260_EPC1_chr10_32635690_-_ARHGAP12_chr10_32120728_length(amino acids)=435AA_start in transcript=303_stop in transcript=1610
MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESDQEKYGLLNVTKIAENGKKVRKNWLSSWAVLQGSSLLFT
KTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPD
SPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVE
EHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQ

--------------------------------------------------------------
>In-frame_ENST00000263062_ENST00000311380_TCGA-HC-8260_EPC1_chr10_32635690_-_ARHGAP12_chr10_32120728_length(transcript)=3799nt_BP=423nt
GAATGGCTGGGGTTGGCTGAAGAGCGCACAGTGGAGTTTTAATGTCCGCCATGTTGGCCATGGCGTATTGAAGAGAGCGAGCGAGAGAGG
AGCGGAGCGGCACAGCCTCCCACCCTCCCGGCTGGTGTTAGTGCCCGGACGGCGGGCTCTGCGCTCCGCCCCTCAAGTCCCCGGCAGCGG
TTGGCGAGTGGGGACCGAACCCCCGGTTCTCCATGATCCCGCTGGCCGGGGCCGTTTCCCCAGAGCGGAGAGGTATCTGCTGCGCCTGAG
ATGAGTAAACTGTCGTTTCGGGCGCGGGCGCTAGACGCCTCGAAGCCGCTGCCGGTTTTCCGCTGTGAGGATCTGCCCGACCTGCACGAA
TACGCCTCGATAAACAGGGCCGTGCCGCAGATGCCCACCGGAATGGAGAAGGAAGAGGAGTCGGATCAAGAGAAATATGGATTATTAAAT
GTAACAAAAATTGCTGAAAATGGGAAAAAGGTTCGAAAGAACTGGTTGTCTTCTTGGGCGGTGTTGCAGGGTTCATCTTTACTTTTTACC
AAAACTCAAGGAAGTAGCACAAGTTGGTTTGGCAGTAATCAGTCCAAACCAGAGTTCACAGTGGACCTCAAGGGGGCAACAATTGAGATG
GCTTCAAAGGATAAATCCAGCAAAAAGAATGTATTTGAGCTGAAAACTCGTCAAGGAACAGAACTGCTAATTCAGTCTGACAATGACACT
GTTATTAATGATTGGTTTAAAGTTCTTAGTAGTACAATCAATAATCAGGCAGTAGAAACTGATGAAGGAATTGAAGAGGAGATACCGGAT
TCACCAGGAATAGAAAAGCATGATAAAGAAAAGGAACAAAAGGATCCCAAAAAGCTTCGTTCCTTTAAAGTATCTAGCATAGATTCTTCA
GAACAGAAAAAAACCAAGAAAAACTTAAAGAAGTTTCTTACACGACGCCCCACTTTGCAAGCTGTTCGTGAAAAAGGTTATATTAAAGAT
CAGGTATTTGGATCCAATCTCGCTAATCTGTGTCAGAGAGAGAATGGCACAGTACCAAAGTTTGTGAAGTTATGTATTGAACATGTTGAA
GAACATGGTTTGGATATTGATGGGATATACAGAGTAAGTGGCAACCTCGCAGTGATCCAGAAACTAAGGTTTGCAGTCAATCATGATGAG
AAATTGGACTTGAATGACAGTAAATGGGAAGATATTCATGTCATTACTGGAGCCCTCAAAATGTTTTTTCGAGAATTACCAGAACCTCTT
TTTACATTTAATCATTTTAATGATTTTGTTAATGCAATTAAGCAAGAACCAAGACAGCGAGTCGCTGCTGTTAAGGACCTAATCAGACAG
TTGCCAAAGCCAAACCAAGACACAATGCAGATTCTTTTCCGACATCTCAGAAGAGTTATAGAAAATGGAGAGAAAAATCGAATGACCTAT
CAGAGTATAGCAATTGTTTTTGGTCCCACTCTATTAAAACCAGAAAAAGAGACTGGTAATATAGCAGTTCATACTGTGTACCAGAATCAG
ATTGTAGAATTAATTCTTCTGGAACTGAGTTCCATCTTCGGACGTTGATTCTTACTGAAGACAACCTGTGGAATAGAAGCTGGATTCCAT
CAGATTTCAAATGTTTATACACAATGTATTTTATTTTTTGGACCAAGCAGTGACTCTTTGATTTTGCACTTTTTTTTTGAGGGATCAGAA
GGGAAGGGGAGAGTCGAGATGTGTGTTAGGCCCTCATATTTGCTGCTTTGTTGCAAGTTGATATAACTGCGTGTAATTATGAATTCATTT
TATCCTGAATGTTTGCATTTCATACTCTGAATTTCAGTAAAAATCAAAACTTAAAATTCTAACCAGTCATATACACTGGATAATTTGGTA
AGAAAACTGTATTTTTTTTCCCTGAAATTGGATAATGTACTTTCTTCTCAAGATTCATGACTTGATAGAACAATACTTTCAGTTATGTTG
CAAAGGCTCTTGGGCATTTTAAACAAAATGAAGTATATCCATTTTGAAACCTGTGTATTTCTTTTTCGGGGTTTCTGCATGCAGTGGCAG
TCTTAAGTGCCAAAATTCATTATAACCCCAAAATAACCCCTTGATGAAGGCTTGCTGTCTTTTACTGTGTTACACAGCATCCTTACTGGA
TATCTTAGTTGCTTGTTTGGGCAGCACACTAATATTACTTAAAACACTGTGATATACTGGAGTTTTAGTTAGCGGAAGTCAGTTCAGGGC
ATTTTAGGGCTGTCTTGCTATACTGAATTGTAGCTAACAATCCTAATTATATCTAGTACCATACTGAGTTATTGGTATGACCCTGTGGAA
ACACACATTATTTTATGTAAATATAGGCTAAAGACTTAATGTCCTTTAGCTTGTGTATATAATTGTGTTGTATAGTCTCAGAGTACATTC
TAACCCTACATTTCTAATCATTGTTATTGGTAATCTTTTCTGTGAATATTAGGTTTCCTCCAGAAATAGTCCGTTATTTGGGAAAGTTAA
CTGTGTGCACTTTTAGATATTAACTACATTTACAGGCAAATCACTGTAATGAGAATGGTACTGGAAAAATACTGAATAGACTTGCTAAAT
GGCACATGCACTACAAGAGGAACCTTTTGGGTTATTTAATATGTACAGAAAACATTAGAAAAAATTTATTACAGAATTCTAATTCCAGTA
TGAATAGTGGAAACCCATCTGTAAATTAGATGGATGTTGGATGGAAAATGACATTGCTAAATTTGAGAATTTCTTTTTACCTACTAATGT
AGATTGCTTTGTATAATAAAACACAGGGTTTGGAAGGTTTTGTTACAGGGAGCATGGTCTGTTGAAGATTTTTAAAATGTATTTTTCTAG
ATTAACTTCTGTACATGAAATGTCTAATAAAACTATAAGAGGTTTAGAGATTTTTCCATTGGAAATGTGCATTTTGGTTTCTAATTTTTT
TGTTTTTTCATTTACTGGCATACTGTTATACCTCATTTTTAAAAATCAACTGAATCCAATATTTCCTGTGGCAAATAACACTTTCCTCAT
TTCATACCTTTTCTCCTCTCTTCCATGCCAACATTTCTCCACCCACAACGTACACTTTTTATTTCTCCATCAATATTTGAAAGCGAGTGA
TTTGTGACCAGGATTTTTTTTTCTTAGGGTTGCATTTATAATTTACAGATTGCCTTCCTTGGGAACAAGTATTTTTTTGTATGATCTGTC
TAAAAACCTCTCACCTGAATTTTGTGGTAGAAAGTCTGTATTTGTTGTTGTGAGCGTGTTAAATTGATAACAAACCAAACTACTTGATAG
CTAAAGCAGATTGTTTCGGGTGGGGAGAAAAAGCCCTAAATCAGAATGTTTATATTTGCCTAAAGATGTCCTTAATAATACAATATGCTT
TAGATCTTGCTTATTTAGTGATTGTATACCAGGAAAACAATTAGACTCAAATCAGTGATGTTCTTGTTCTTGGTGTTCATGAACATATAT
CAAAGATTAAAATTGTCCTGTGTTTCTTGTTTCAAGGTACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGAAGTCTTAAATGT
TTTATTAGTCTACAGCTAATCAGTTTATTGTAATATTGTATGTACAGTGAGATTAATGTCTTGCGTTTTCATCCTTTGTGAATTAAAAAT
TCTCACTTGTTTTGTAATAACAAAGCTAGTAATATTTTCCTGTCTTGACAGCTTGGTTTTATAGTAGAAAATATATTAAAAGCTGAAATA

>In-frame_ENST00000263062_ENST00000311380_TCGA-HC-8260_EPC1_chr10_32635690_-_ARHGAP12_chr10_32120728_length(amino acids)=435AA_start in transcript=270_stop in transcript=1577
MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESDQEKYGLLNVTKIAENGKKVRKNWLSSWAVLQGSSLLFT
KTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPD
SPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVE
EHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQ

--------------------------------------------------------------
>In-frame_ENST00000263062_ENST00000375250_TCGA-HC-8260_EPC1_chr10_32635690_-_ARHGAP12_chr10_32120728_length(transcript)=3799nt_BP=423nt
GAATGGCTGGGGTTGGCTGAAGAGCGCACAGTGGAGTTTTAATGTCCGCCATGTTGGCCATGGCGTATTGAAGAGAGCGAGCGAGAGAGG
AGCGGAGCGGCACAGCCTCCCACCCTCCCGGCTGGTGTTAGTGCCCGGACGGCGGGCTCTGCGCTCCGCCCCTCAAGTCCCCGGCAGCGG
TTGGCGAGTGGGGACCGAACCCCCGGTTCTCCATGATCCCGCTGGCCGGGGCCGTTTCCCCAGAGCGGAGAGGTATCTGCTGCGCCTGAG
ATGAGTAAACTGTCGTTTCGGGCGCGGGCGCTAGACGCCTCGAAGCCGCTGCCGGTTTTCCGCTGTGAGGATCTGCCCGACCTGCACGAA
TACGCCTCGATAAACAGGGCCGTGCCGCAGATGCCCACCGGAATGGAGAAGGAAGAGGAGTCGGATCAAGAGAAATATGGATTATTAAAT
GTAACAAAAATTGCTGAAAATGGGAAAAAGGTTCGAAAGAACTGGTTGTCTTCTTGGGCGGTGTTGCAGGGTTCATCTTTACTTTTTACC
AAAACTCAAGGAAGTAGCACAAGTTGGTTTGGCAGTAATCAGTCCAAACCAGAGTTCACAGTGGACCTCAAGGGGGCAACAATTGAGATG
GCTTCAAAGGATAAATCCAGCAAAAAGAATGTATTTGAGCTGAAAACTCGTCAAGGAACAGAACTGCTAATTCAGTCTGACAATGACACT
GTTATTAATGATTGGTTTAAAGTTCTTAGTAGTACAATCAATAATCAGGCAGTAGAAACTGATGAAGGAATTGAAGAGGAGATACCGGAT
TCACCAGGAATAGAAAAGCATGATAAAGAAAAGGAACAAAAGGATCCCAAAAAGCTTCGTTCCTTTAAAGTATCTAGCATAGATTCTTCA
GAACAGAAAAAAACCAAGAAAAACTTAAAGAAGTTTCTTACACGACGCCCCACTTTGCAAGCTGTTCGTGAAAAAGGTTATATTAAAGAT
CAGGTATTTGGATCCAATCTCGCTAATCTGTGTCAGAGAGAGAATGGCACAGTACCAAAGTTTGTGAAGTTATGTATTGAACATGTTGAA
GAACATGGTTTGGATATTGATGGGATATACAGAGTAAGTGGCAACCTCGCAGTGATCCAGAAACTAAGGTTTGCAGTCAATCATGATGAG
AAATTGGACTTGAATGACAGTAAATGGGAAGATATTCATGTCATTACTGGAGCCCTCAAAATGTTTTTTCGAGAATTACCAGAACCTCTT
TTTACATTTAATCATTTTAATGATTTTGTTAATGCAATTAAGCAAGAACCAAGACAGCGAGTCGCTGCTGTTAAGGACCTAATCAGACAG
TTGCCAAAGCCAAACCAAGACACAATGCAGATTCTTTTCCGACATCTCAGAAGAGTTATAGAAAATGGAGAGAAAAATCGAATGACCTAT
CAGAGTATAGCAATTGTTTTTGGTCCCACTCTATTAAAACCAGAAAAAGAGACTGGTAATATAGCAGTTCATACTGTGTACCAGAATCAG
ATTGTAGAATTAATTCTTCTGGAACTGAGTTCCATCTTCGGACGTTGATTCTTACTGAAGACAACCTGTGGAATAGAAGCTGGATTCCAT
CAGATTTCAAATGTTTATACACAATGTATTTTATTTTTTGGACCAAGCAGTGACTCTTTGATTTTGCACTTTTTTTTTGAGGGATCAGAA
GGGAAGGGGAGAGTCGAGATGTGTGTTAGGCCCTCATATTTGCTGCTTTGTTGCAAGTTGATATAACTGCGTGTAATTATGAATTCATTT
TATCCTGAATGTTTGCATTTCATACTCTGAATTTCAGTAAAAATCAAAACTTAAAATTCTAACCAGTCATATACACTGGATAATTTGGTA
AGAAAACTGTATTTTTTTTCCCTGAAATTGGATAATGTACTTTCTTCTCAAGATTCATGACTTGATAGAACAATACTTTCAGTTATGTTG
CAAAGGCTCTTGGGCATTTTAAACAAAATGAAGTATATCCATTTTGAAACCTGTGTATTTCTTTTTCGGGGTTTCTGCATGCAGTGGCAG
TCTTAAGTGCCAAAATTCATTATAACCCCAAAATAACCCCTTGATGAAGGCTTGCTGTCTTTTACTGTGTTACACAGCATCCTTACTGGA
TATCTTAGTTGCTTGTTTGGGCAGCACACTAATATTACTTAAAACACTGTGATATACTGGAGTTTTAGTTAGCGGAAGTCAGTTCAGGGC
ATTTTAGGGCTGTCTTGCTATACTGAATTGTAGCTAACAATCCTAATTATATCTAGTACCATACTGAGTTATTGGTATGACCCTGTGGAA
ACACACATTATTTTATGTAAATATAGGCTAAAGACTTAATGTCCTTTAGCTTGTGTATATAATTGTGTTGTATAGTCTCAGAGTACATTC
TAACCCTACATTTCTAATCATTGTTATTGGTAATCTTTTCTGTGAATATTAGGTTTCCTCCAGAAATAGTCCGTTATTTGGGAAAGTTAA
CTGTGTGCACTTTTAGATATTAACTACATTTACAGGCAAATCACTGTAATGAGAATGGTACTGGAAAAATACTGAATAGACTTGCTAAAT
GGCACATGCACTACAAGAGGAACCTTTTGGGTTATTTAATATGTACAGAAAACATTAGAAAAAATTTATTACAGAATTCTAATTCCAGTA
TGAATAGTGGAAACCCATCTGTAAATTAGATGGATGTTGGATGGAAAATGACATTGCTAAATTTGAGAATTTCTTTTTACCTACTAATGT
AGATTGCTTTGTATAATAAAACACAGGGTTTGGAAGGTTTTGTTACAGGGAGCATGGTCTGTTGAAGATTTTTAAAATGTATTTTTCTAG
ATTAACTTCTGTACATGAAATGTCTAATAAAACTATAAGAGGTTTAGAGATTTTTCCATTGGAAATGTGCATTTTGGTTTCTAATTTTTT
TGTTTTTTCATTTACTGGCATACTGTTATACCTCATTTTTAAAAATCAACTGAATCCAATATTTCCTGTGGCAAATAACACTTTCCTCAT
TTCATACCTTTTCTCCTCTCTTCCATGCCAACATTTCTCCACCCACAACGTACACTTTTTATTTCTCCATCAATATTTGAAAGCGAGTGA
TTTGTGACCAGGATTTTTTTTTCTTAGGGTTGCATTTATAATTTACAGATTGCCTTCCTTGGGAACAAGTATTTTTTTGTATGATCTGTC
TAAAAACCTCTCACCTGAATTTTGTGGTAGAAAGTCTGTATTTGTTGTTGTGAGCGTGTTAAATTGATAACAAACCAAACTACTTGATAG
CTAAAGCAGATTGTTTCGGGTGGGGAGAAAAAGCCCTAAATCAGAATGTTTATATTTGCCTAAAGATGTCCTTAATAATACAATATGCTT
TAGATCTTGCTTATTTAGTGATTGTATACCAGGAAAACAATTAGACTCAAATCAGTGATGTTCTTGTTCTTGGTGTTCATGAACATATAT
CAAAGATTAAAATTGTCCTGTGTTTCTTGTTTCAAGGTACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGAAGTCTTAAATGT
TTTATTAGTCTACAGCTAATCAGTTTATTGTAATATTGTATGTACAGTGAGATTAATGTCTTGCGTTTTCATCCTTTGTGAATTAAAAAT
TCTCACTTGTTTTGTAATAACAAAGCTAGTAATATTTTCCTGTCTTGACAGCTTGGTTTTATAGTAGAAAATATATTAAAAGCTGAAATA

>In-frame_ENST00000263062_ENST00000375250_TCGA-HC-8260_EPC1_chr10_32635690_-_ARHGAP12_chr10_32120728_length(amino acids)=435AA_start in transcript=270_stop in transcript=1577
MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESDQEKYGLLNVTKIAENGKKVRKNWLSSWAVLQGSSLLFT
KTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPD
SPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVE
EHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for EPC1-ARHGAP12


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EPC1-ARHGAP12


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EPC1-ARHGAP12


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource