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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EPHA5-RUFY3 (FusionGDB2 ID:26934)

Fusion Gene Summary for EPHA5-RUFY3

check button Fusion gene summary
Fusion gene informationFusion gene name: EPHA5-RUFY3
Fusion gene ID: 26934
HgeneTgene
Gene symbol

EPHA5

RUFY3

Gene ID

2044

79443

Gene nameEPH receptor A5FYVE and coiled-coil domain autophagy adaptor 1
SynonymsCEK7|EHK-1|EHK1|EK7|HEK7|TYRO4CATC2|CTRCT18|RUFY3|ZFYVE7
Cytomap

4q13.1-q13.2

3p21.31

Type of geneprotein-codingprotein-coding
Descriptionephrin type-A receptor 5EPH homology kinase 1EPH-like kinase 7brain-specific kinaseepididymis secretory sperm binding proteinreceptor protein-tyrosine kinase HEK7tyrosine-protein kinase receptor EHK-1FYVE and coiled-coil domain-containing protein 1FYVE and coiled-coil domain containing 1RUN and FYVE domain containing 3zinc finger FYVE domain-containing protein 7
Modification date2020031320200313
UniProtAcc

P54756

.
Ensembl transtripts involved in fusion geneENST00000273854, ENST00000432638, 
ENST00000354839, ENST00000511294, 
ENST00000417478, ENST00000381006, 
ENST00000226328, ENST00000536664, 
ENST00000502653, ENST00000512331, 
Fusion gene scores* DoF score3 X 3 X 2=185 X 5 X 4=100
# samples 35
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EPHA5 [Title/Abstract] AND RUFY3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEPHA5(66356095)-RUFY3(71628236), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across EPHA5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across RUFY3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-91-6848-01AEPHA5chr4

66356095

-RUFY3chr4

71628236

+
ChimerDB4LUADTCGA-91-6848-01AEPHA5chr4

66356095

-RUFY3chr4

71628236

+


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Fusion Gene ORF analysis for EPHA5-RUFY3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000273854ENST00000417478EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000273854ENST00000381006EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000273854ENST00000226328EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000273854ENST00000536664EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000273854ENST00000502653EPHA5chr4

66356095

-RUFY3chr4

71628236

+
5CDS-intronENST00000273854ENST00000512331EPHA5chr4

66356095

-RUFY3chr4

71628236

+
intron-3CDSENST00000432638ENST00000417478EPHA5chr4

66356095

-RUFY3chr4

71628236

+
intron-3CDSENST00000432638ENST00000381006EPHA5chr4

66356095

-RUFY3chr4

71628236

+
intron-3CDSENST00000432638ENST00000226328EPHA5chr4

66356095

-RUFY3chr4

71628236

+
intron-3CDSENST00000432638ENST00000536664EPHA5chr4

66356095

-RUFY3chr4

71628236

+
intron-3CDSENST00000432638ENST00000502653EPHA5chr4

66356095

-RUFY3chr4

71628236

+
intron-intronENST00000432638ENST00000512331EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000354839ENST00000417478EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000354839ENST00000381006EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000354839ENST00000226328EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000354839ENST00000536664EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000354839ENST00000502653EPHA5chr4

66356095

-RUFY3chr4

71628236

+
5CDS-intronENST00000354839ENST00000512331EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000511294ENST00000417478EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000511294ENST00000381006EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000511294ENST00000226328EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000511294ENST00000536664EPHA5chr4

66356095

-RUFY3chr4

71628236

+
In-frameENST00000511294ENST00000502653EPHA5chr4

66356095

-RUFY3chr4

71628236

+
5CDS-intronENST00000511294ENST00000512331EPHA5chr4

66356095

-RUFY3chr4

71628236

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000273854EPHA5chr466356095-ENST00000417478RUFY3chr471628236+365220036013165854
ENST00000273854EPHA5chr466356095-ENST00000381006RUFY3chr471628236+4344200360136871028
ENST00000273854EPHA5chr466356095-ENST00000226328RUFY3chr471628236+549520036013234877
ENST00000273854EPHA5chr466356095-ENST00000536664RUFY3chr471628236+327320036013234877
ENST00000273854EPHA5chr466356095-ENST00000502653RUFY3chr471628236+4131200360136871028
ENST00000354839EPHA5chr466356095-ENST00000417478RUFY3chr471628236+324415951932757854
ENST00000354839EPHA5chr466356095-ENST00000381006RUFY3chr471628236+3936159519332791028
ENST00000354839EPHA5chr466356095-ENST00000226328RUFY3chr471628236+508715951932826877
ENST00000354839EPHA5chr466356095-ENST00000536664RUFY3chr471628236+286515951932826877
ENST00000354839EPHA5chr466356095-ENST00000502653RUFY3chr471628236+3723159519332791028
ENST00000511294EPHA5chr466356095-ENST00000417478RUFY3chr471628236+380421557533317854
ENST00000511294EPHA5chr466356095-ENST00000381006RUFY3chr471628236+4496215575338391028
ENST00000511294EPHA5chr466356095-ENST00000226328RUFY3chr471628236+564721557533386877
ENST00000511294EPHA5chr466356095-ENST00000536664RUFY3chr471628236+342521557533386877
ENST00000511294EPHA5chr466356095-ENST00000502653RUFY3chr471628236+4283215575338391028

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000273854ENST00000417478EPHA5chr466356095-RUFY3chr471628236+0.0024098410.9975902
ENST00000273854ENST00000381006EPHA5chr466356095-RUFY3chr471628236+0.0027367340.9972633
ENST00000273854ENST00000226328EPHA5chr466356095-RUFY3chr471628236+0.0003591450.9996408
ENST00000273854ENST00000536664EPHA5chr466356095-RUFY3chr471628236+0.0036062920.99639374
ENST00000273854ENST00000502653EPHA5chr466356095-RUFY3chr471628236+0.0038710380.9961289
ENST00000354839ENST00000417478EPHA5chr466356095-RUFY3chr471628236+0.0025465780.9974534
ENST00000354839ENST00000381006EPHA5chr466356095-RUFY3chr471628236+0.0019695160.9980305
ENST00000354839ENST00000226328EPHA5chr466356095-RUFY3chr471628236+0.0003297950.99967027
ENST00000354839ENST00000536664EPHA5chr466356095-RUFY3chr471628236+0.0039146270.9960854
ENST00000354839ENST00000502653EPHA5chr466356095-RUFY3chr471628236+0.0030361120.9969639
ENST00000511294ENST00000417478EPHA5chr466356095-RUFY3chr471628236+0.0028824320.99711764
ENST00000511294ENST00000381006EPHA5chr466356095-RUFY3chr471628236+0.0036627480.9963373
ENST00000511294ENST00000226328EPHA5chr466356095-RUFY3chr471628236+0.0004029240.99959713
ENST00000511294ENST00000536664EPHA5chr466356095-RUFY3chr471628236+0.0046238770.9953761
ENST00000511294ENST00000502653EPHA5chr466356095-RUFY3chr471628236+0.0050929860.99490696

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Fusion Genomic Features for EPHA5-RUFY3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EPHA5chr466356094-RUFY3chr471628235+9.01E-091
EPHA5chr466356094-RUFY3chr471628235+9.01E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for EPHA5-RUFY3


check button Go to

FGviewer for the breakpoints of chr4:66356095-chr4:71628236

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EPHA5

P54756

.
FUNCTION: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity). {ECO:0000250}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEPHA5chr4:66356095chr4:71628236ENST00000273854-518220_354467.33333333333331038.0Compositional biasNote=Cys-rich
HgeneEPHA5chr4:66356095chr4:71628236ENST00000354839-517220_354467.33333333333331016.0Compositional biasNote=Cys-rich
HgeneEPHA5chr4:66356095chr4:71628236ENST00000273854-518357_467467.33333333333331038.0DomainFibronectin type-III 1
HgeneEPHA5chr4:66356095chr4:71628236ENST00000273854-51860_238467.33333333333331038.0DomainEph LBD
HgeneEPHA5chr4:66356095chr4:71628236ENST00000354839-517357_467467.33333333333331016.0DomainFibronectin type-III 1
HgeneEPHA5chr4:66356095chr4:71628236ENST00000354839-51760_238467.33333333333331016.0DomainEph LBD
TgeneRUFY3chr4:66356095chr4:71628236ENST00000226328013267_46459.333333333333336470.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY3chr4:66356095chr4:71628236ENST00000381006018267_46459.333333333333336621.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY3chr4:66356095chr4:71628236ENST00000417478012267_464119.33333333333333507.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY3chr4:66356095chr4:71628236ENST00000502653119267_4646.333333333333333568.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY3chr4:66356095chr4:71628236ENST0000022632801395_22759.333333333333336470.0DomainRUN
TgeneRUFY3chr4:66356095chr4:71628236ENST0000038100601895_22759.333333333333336621.0DomainRUN
TgeneRUFY3chr4:66356095chr4:71628236ENST0000050265311995_2276.333333333333333568.0DomainRUN

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEPHA5chr4:66356095chr4:71628236ENST00000273854-518468_562467.33333333333331038.0DomainFibronectin type-III 2
HgeneEPHA5chr4:66356095chr4:71628236ENST00000273854-518675_936467.33333333333331038.0DomainProtein kinase
HgeneEPHA5chr4:66356095chr4:71628236ENST00000273854-518965_1029467.33333333333331038.0DomainSAM
HgeneEPHA5chr4:66356095chr4:71628236ENST00000354839-517468_562467.33333333333331016.0DomainFibronectin type-III 2
HgeneEPHA5chr4:66356095chr4:71628236ENST00000354839-517675_936467.33333333333331016.0DomainProtein kinase
HgeneEPHA5chr4:66356095chr4:71628236ENST00000354839-517965_1029467.33333333333331016.0DomainSAM
HgeneEPHA5chr4:66356095chr4:71628236ENST00000273854-5181035_1037467.33333333333331038.0MotifPDZ-binding
HgeneEPHA5chr4:66356095chr4:71628236ENST00000354839-5171035_1037467.33333333333331016.0MotifPDZ-binding
HgeneEPHA5chr4:66356095chr4:71628236ENST00000273854-518681_689467.33333333333331038.0Nucleotide bindingATP
HgeneEPHA5chr4:66356095chr4:71628236ENST00000354839-517681_689467.33333333333331016.0Nucleotide bindingATP
HgeneEPHA5chr4:66356095chr4:71628236ENST00000273854-51825_573467.33333333333331038.0Topological domainExtracellular
HgeneEPHA5chr4:66356095chr4:71628236ENST00000273854-518595_1037467.33333333333331038.0Topological domainCytoplasmic
HgeneEPHA5chr4:66356095chr4:71628236ENST00000354839-51725_573467.33333333333331016.0Topological domainExtracellular
HgeneEPHA5chr4:66356095chr4:71628236ENST00000354839-517595_1037467.33333333333331016.0Topological domainCytoplasmic
HgeneEPHA5chr4:66356095chr4:71628236ENST00000273854-518574_594467.33333333333331038.0TransmembraneHelical
HgeneEPHA5chr4:66356095chr4:71628236ENST00000354839-517574_594467.33333333333331016.0TransmembraneHelical
TgeneRUFY3chr4:66356095chr4:71628236ENST0000041747801295_227119.33333333333333507.0DomainRUN


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Fusion Gene Sequence for EPHA5-RUFY3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000273854_ENST00000417478_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=3652nt_BP=2003nt
TCCCTCCCCTCTTCAGCACTCAGCCCGCAGCTATTTCCTTCTGCCAGTCTCTTTGAACTCTGGATCTTTGCTTTTGCTCGCTGCTCTCCT
GTTTTTCATTCTCCACATTTTCTCAAGTCCTCTTTCTTTATCCTTAGCCACCCTGCTTTTTTCCTCCTTTTTTAAAAAATCGGAGATTTC
GTCTTAAAATGATTTGCCTTCCTTACCTTCGTCCATTTCAACACTGAAGGCTGCAAAGAACCTTCACCTTTCCCCTAGTGGTATTTAAAA
ATTCTCAATCCGTAAAAAGTCTTTTTGAAAGGCAAAGGAACAGGACCCAGGACCCTCTCGACACCCTTGATCCGAGTCCAGATCTGCACT
AGCAACCAGAACTAATATTTCATTTAACCCCACCAAAGGGGGAGGCGAGAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGT
GGTTCCTACATTTGGAGGAGCCGCGTGCCAGAAGGCGTAGGACCCCAAGGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTG
CGAGGCCGAAGCGGTGGACTGAGCCGCTCGGGACAGCGGCACCGGAGGAGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGG
ACGCCGGCGGCCCCCAAGCGGCGGCGGCGACACCCCCATCACCCCAGCGTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCT
CTGGACGTGCCTTCTCCTGTGCGCCGCACTCCGGACCCTCCTGGCCAGCCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCAT
GGGGGACCTGGGATGGATTGCTTTTCCAAAAAATGGGTGGGAAGAGATTGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCA
AGTATGCAAAGTGATGGAACAGAATCAGAATAACTGGCTTTTGACCAGTTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACT
CAAATTTACCCTGCGGGACTGCAACAGCCTTCCTGGAGGACTGGGGACCTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGA
TCAGAATGGGAGAAACATCAAGGAAAACCAATACATCAAAATTGATACCATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGA
CCGTGTTATGAAACTGAATACAGAGGTCAGAGATGTAGGACCTCTAAGCAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTG
CATTGCTCTGGTTTCTGTGCGTGTATACTATAAAAAATGCCCTTCTGTGGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGC
TGATTCTTCCCAATTGCTCGAAGTGTCAGGCTCCTGTGTCAACCATTCTGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGG
GGAGTGGCTGGTGCCCATCGGGAAATGCATGTGCAAGGCAGGATATGAAGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTT
CAAAGCCTCACCTCACATCCAGAGCTGCGGCAAATGTCCACCTCACAGTTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAA
GGATTATTTCAGGAGAGAGTCTGATCCACCCACAATGGCATGCACAAGACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGA
AACTAGTGTCTTTCTGGAATGGATTCCGCCTGCTGACACTGGTGGAAGGAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTC
CCATGCAGGTGTGTGTGAGGAGTGTGGCGGTCATGTCAGGTACCTTCCCCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGA
TCTACTCGCTCACACAAACTATACCTTTGAGATTGAGGCAGTGAATGGAGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGT
AAATGTAACCACAAATCAAGCAGATCCTAATTATCTCATGGCTAATGAACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGG
CTTGATTGAATCAGCTCTGAACCTGGGGAGGACTCTTGACTCTGACTATGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCT
GAAACATGGCTTGAAAGCTAAAAAAACTTTTCTCGGACAAAATAAATCCTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGA
AGCCGCAGAGATAACAGCAAGTGTTAAAGATCTTCCAGGACTTAAGACACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAAT
GCAAAAGAAACTTTCAGAATATATGAAAGCTTTGATCAATAAGAAAGAACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGA
AGAAGAAGGAGCCATAATTGCTGGTCTGTTGGTGGGTCTGAATGTCATTGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCA
GGTTGGAGTTATAGATTTTTCAATGTATCTCAAGGACGGGAACAGCAGTAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGA
CCAGAAGAACTATGTAGAAGAACTGAACAGACATTTGAATGCTACTGTAAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAA
CACTAAACTGACAGAGGAGCTTGCAGTTGCAAACAACAGGATCATTACCTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTA
CATACTGGAATCCAATCGGAAGGGTCCCAAGCAAGACAGAACTGCAGAAGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGA
GACACAATTACGATTGGATGTTGAGAAAGAACTGGAGATGCAGATCAGCATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAA
GGATGTCTGTGAGAAGCAGGATGCCCTGGTATCTCTTCGGCAGCAGCTGGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCT
GCAGAGTTCAGACTTAGGAGTAAAACAGAAAAGTGAACTAAACAGTCGCTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACA
ACTTGAACAAAGGTAAAAGTCCTGTTTCTTTAATGAAACACTTTGGATTGTCAGTGCTGAAGTGAAAAGAATGTGCTGTACATTCGGCAA
ATAGAAAATACATGAAATTCTTCCAAATTAGCATCAGACATTCTGGTAGAAAAAAGCCAGTTGAATGTTATGTGTGTTTTCTAAGGTATG
ACTGAAATGTTTTTAGGAAATGTCAATCACTTGACTAGCCTTTAAAAAAAAAAAAGAAAGGTCAGCCTTTTATGACTGTTTTGAACATCA
GAACTCTTAATCCATGTCAGAGTCATGTGTTAGAGGAAGGATACTTAAAAGCATGGAAGGACTCTTAAATGTATGTATGTAATTCTGTGA
TTTTATTGTTCATCACTGAAGTCTTTGAATACTTGGATGCTAGGGGATATAGAGGCACTGAGAGATAGGTGTCCTCCAAGGATCTATTCT

>In-frame_ENST00000273854_ENST00000417478_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=854AA_start in transcript=601_stop in transcript=3165
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR

--------------------------------------------------------------
>In-frame_ENST00000273854_ENST00000381006_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=4344nt_BP=2003nt
TCCCTCCCCTCTTCAGCACTCAGCCCGCAGCTATTTCCTTCTGCCAGTCTCTTTGAACTCTGGATCTTTGCTTTTGCTCGCTGCTCTCCT
GTTTTTCATTCTCCACATTTTCTCAAGTCCTCTTTCTTTATCCTTAGCCACCCTGCTTTTTTCCTCCTTTTTTAAAAAATCGGAGATTTC
GTCTTAAAATGATTTGCCTTCCTTACCTTCGTCCATTTCAACACTGAAGGCTGCAAAGAACCTTCACCTTTCCCCTAGTGGTATTTAAAA
ATTCTCAATCCGTAAAAAGTCTTTTTGAAAGGCAAAGGAACAGGACCCAGGACCCTCTCGACACCCTTGATCCGAGTCCAGATCTGCACT
AGCAACCAGAACTAATATTTCATTTAACCCCACCAAAGGGGGAGGCGAGAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGT
GGTTCCTACATTTGGAGGAGCCGCGTGCCAGAAGGCGTAGGACCCCAAGGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTG
CGAGGCCGAAGCGGTGGACTGAGCCGCTCGGGACAGCGGCACCGGAGGAGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGG
ACGCCGGCGGCCCCCAAGCGGCGGCGGCGACACCCCCATCACCCCAGCGTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCT
CTGGACGTGCCTTCTCCTGTGCGCCGCACTCCGGACCCTCCTGGCCAGCCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCAT
GGGGGACCTGGGATGGATTGCTTTTCCAAAAAATGGGTGGGAAGAGATTGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCA
AGTATGCAAAGTGATGGAACAGAATCAGAATAACTGGCTTTTGACCAGTTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACT
CAAATTTACCCTGCGGGACTGCAACAGCCTTCCTGGAGGACTGGGGACCTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGA
TCAGAATGGGAGAAACATCAAGGAAAACCAATACATCAAAATTGATACCATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGA
CCGTGTTATGAAACTGAATACAGAGGTCAGAGATGTAGGACCTCTAAGCAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTG
CATTGCTCTGGTTTCTGTGCGTGTATACTATAAAAAATGCCCTTCTGTGGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGC
TGATTCTTCCCAATTGCTCGAAGTGTCAGGCTCCTGTGTCAACCATTCTGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGG
GGAGTGGCTGGTGCCCATCGGGAAATGCATGTGCAAGGCAGGATATGAAGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTT
CAAAGCCTCACCTCACATCCAGAGCTGCGGCAAATGTCCACCTCACAGTTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAA
GGATTATTTCAGGAGAGAGTCTGATCCACCCACAATGGCATGCACAAGACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGA
AACTAGTGTCTTTCTGGAATGGATTCCGCCTGCTGACACTGGTGGAAGGAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTC
CCATGCAGGTGTGTGTGAGGAGTGTGGCGGTCATGTCAGGTACCTTCCCCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGA
TCTACTCGCTCACACAAACTATACCTTTGAGATTGAGGCAGTGAATGGAGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGT
AAATGTAACCACAAATCAAGCAGATCCTAATTATCTCATGGCTAATGAACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGG
CTTGATTGAATCAGCTCTGAACCTGGGGAGGACTCTTGACTCTGACTATGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCT
GAAACATGGCTTGAAAGCTAAAAAAACTTTTCTCGGACAAAATAAATCCTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGA
AGCCGCAGAGATAACAGCAAGTGTTAAAGATCTTCCAGGACTTAAGACACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAAT
GCAAAAGAAACTTTCAGAATATATGAAAGCTTTGATCAATAAGAAAGAACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGA
AGAAGAAGGAGCCATAATTGCTGGTCTGTTGGTGGGTCTGAATGTCATTGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCA
GGTTGGAGTTATAGATTTTTCAATGTATCTCAAGGACGGGAACAGCAGTAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGA
CCAGAAGAACTATGTAGAAGAACTGAACAGACATTTGAATGCTACTGTAAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAA
CACTAAACTGACAGAGGAGCTTGCAGTTGCAAACAACAGGATCATTACCTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTA
CATACTGGAATCCAATCGGAAGGGTCCCAAGCAAGACAGAACTGCAGAAGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGA
GACACAATTACGATTGGATGTTGAGAAAGAACTGGAGATGCAGATCAGCATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAA
GGATGTCTGTGAGAAGCAGGATGCCCTGGTATCTCTTCGGCAGCAGCTGGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCT
GCAGAGTTCAGACTTAGGAGTAAAACAGAAAAGTGAACTAAACAGTCGCTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACA
ACTTGAACAAAGATTGCGCCAGGCTGAGCGAAGCCGCCAATCTGCTGAGTTGGACAACCGGCTCTTCAAACAGGACTTTGGAGACAAGAT
CAACAGTCTGCAGCTGGAAGTCGAGGAGCTCACCAGGCAGCGGAACCAGCTTGAGTTAGAACTAAAACAGGAAAAAGAAAGAAGATTACA
AAACGACAGGAGCATCCCAGGAAGGGGTTCCCAGAAGTCAGAATCCAAGATGGATGGGAAGCACAAAATGCAAGAGGAAAATGTTAAACT
AAAAAAGCCCCTGGAAGAAAGCCACAGGCTGCAACCCCACCCTATGGATGAACAGGATCAGCTGCTGCTCTCTGAAAAGCCACAGTTGTG
TCAGCTATGCCAGGAAGACGGCAGCCTAACAAAGAATGTGTGTAAGAACTGCAGCGGAACCTTCTGTGATGCCTGTTCAACAAATGAACT
GCCTCTTCCTTCAAGTATCAAGCTTGAGCGAGTTTGCAATCCCTGTCACAAGCATCTGATGAAGCAATATTCTACCAGCCCATCATAAGA
CTGGAGGCCAAGACCTGGACCAAAACGTTTATGCAGGCTCCTCTGTACCTGTGTTTTAGCTGTCAGGATCTCATAGAGCCCAGTTCTTAG
AGTCAACTAAAGAGTTGATAGGAATTTACTAGGTCCAGGGAGAAAAGGCAGTGGTTGGGGTTACTGGAAATTTTGCTCATTTTCTCTAAT
GACTGTATGAATAAAAGTGAACTTACTTGAGCCTTTCTCTTCTAAATCTAAACAACCTGATATTGAAGGTTTGCTTTATAGCATATCTTT
GGAAAGGCAACTCATTTTTATGATTAGTGATACTGGGGTGGATTTAATAGGAGAGAGAATCCAGGCAGATAAGAATAAAAAGGAAAATGA
TCATCTCCTTCTATAGCATTTGCAGATTCAAGGGGGAGAGGTAGATGCTGAGATCAAAATGACAGTTGTTACTTATTTTTCCAGGTGCTG
TTAGTATAAACATTGTTTCCTCTTCACCCCTGCTAACTACCTCTTTAAAGTATTTCTACCAAACTGTGAACCCAATCTCAGGGAAAAGAA
ATTAAAAAGTAATATAAATTCTGCATATATTAAAAACAATATTGTAATATGTTATAATTTCAGGACCAGAATTTTCTGGTCTTTACCTAC

>In-frame_ENST00000273854_ENST00000381006_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=1028AA_start in transcript=601_stop in transcript=3687
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR
ALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNRLFKQDFGDKINSLQLEVEELTRQRNQLELE
LKQEKERRLQNDRSIPGRGSQKSESKMDGKHKMQEENVKLKKPLEESHRLQPHPMDEQDQLLLSEKPQLCQLCQEDGSLTKNVCKNCSGT

--------------------------------------------------------------
>In-frame_ENST00000273854_ENST00000226328_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=5495nt_BP=2003nt
TCCCTCCCCTCTTCAGCACTCAGCCCGCAGCTATTTCCTTCTGCCAGTCTCTTTGAACTCTGGATCTTTGCTTTTGCTCGCTGCTCTCCT
GTTTTTCATTCTCCACATTTTCTCAAGTCCTCTTTCTTTATCCTTAGCCACCCTGCTTTTTTCCTCCTTTTTTAAAAAATCGGAGATTTC
GTCTTAAAATGATTTGCCTTCCTTACCTTCGTCCATTTCAACACTGAAGGCTGCAAAGAACCTTCACCTTTCCCCTAGTGGTATTTAAAA
ATTCTCAATCCGTAAAAAGTCTTTTTGAAAGGCAAAGGAACAGGACCCAGGACCCTCTCGACACCCTTGATCCGAGTCCAGATCTGCACT
AGCAACCAGAACTAATATTTCATTTAACCCCACCAAAGGGGGAGGCGAGAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGT
GGTTCCTACATTTGGAGGAGCCGCGTGCCAGAAGGCGTAGGACCCCAAGGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTG
CGAGGCCGAAGCGGTGGACTGAGCCGCTCGGGACAGCGGCACCGGAGGAGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGG
ACGCCGGCGGCCCCCAAGCGGCGGCGGCGACACCCCCATCACCCCAGCGTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCT
CTGGACGTGCCTTCTCCTGTGCGCCGCACTCCGGACCCTCCTGGCCAGCCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCAT
GGGGGACCTGGGATGGATTGCTTTTCCAAAAAATGGGTGGGAAGAGATTGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCA
AGTATGCAAAGTGATGGAACAGAATCAGAATAACTGGCTTTTGACCAGTTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACT
CAAATTTACCCTGCGGGACTGCAACAGCCTTCCTGGAGGACTGGGGACCTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGA
TCAGAATGGGAGAAACATCAAGGAAAACCAATACATCAAAATTGATACCATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGA
CCGTGTTATGAAACTGAATACAGAGGTCAGAGATGTAGGACCTCTAAGCAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTG
CATTGCTCTGGTTTCTGTGCGTGTATACTATAAAAAATGCCCTTCTGTGGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGC
TGATTCTTCCCAATTGCTCGAAGTGTCAGGCTCCTGTGTCAACCATTCTGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGG
GGAGTGGCTGGTGCCCATCGGGAAATGCATGTGCAAGGCAGGATATGAAGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTT
CAAAGCCTCACCTCACATCCAGAGCTGCGGCAAATGTCCACCTCACAGTTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAA
GGATTATTTCAGGAGAGAGTCTGATCCACCCACAATGGCATGCACAAGACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGA
AACTAGTGTCTTTCTGGAATGGATTCCGCCTGCTGACACTGGTGGAAGGAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTC
CCATGCAGGTGTGTGTGAGGAGTGTGGCGGTCATGTCAGGTACCTTCCCCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGA
TCTACTCGCTCACACAAACTATACCTTTGAGATTGAGGCAGTGAATGGAGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGT
AAATGTAACCACAAATCAAGCAGATCCTAATTATCTCATGGCTAATGAACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGG
CTTGATTGAATCAGCTCTGAACCTGGGGAGGACTCTTGACTCTGACTATGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCT
GAAACATGGCTTGAAAGCTAAAAAAACTTTTCTCGGACAAAATAAATCCTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGA
AGCCGCAGAGATAACAGCAAGTGTTAAAGATCTTCCAGGACTTAAGACACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAAT
GCAAAAGAAACTTTCAGAATATATGAAAGCTTTGATCAATAAGAAAGAACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGA
AGAAGAAGGAGCCATAATTGCTGGTCTGTTGGTGGGTCTGAATGTCATTGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCA
GGTTGGAGTTATAGATTTTTCAATGTATCTCAAGGACGGGAACAGCAGTAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGA
CCAGAAGAACTATGTAGAAGAACTGAACAGACATTTGAATGCTACTGTAAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAA
CACTAAACTGACAGAGGAGCTTGCAGTTGCAAACAACAGGATCATTACCTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTA
CATACTGGAATCCAATCGGAAGGGTCCCAAGCAAGACAGAACTGCAGAAGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGA
GACACAATTACGATTGGATGTTGAGAAAGAACTGGAGATGCAGATCAGCATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAA
GGATGTCTGTGAGAAGCAGGATGCCCTGGTATCTCTTCGGCAGCAGCTGGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCT
GCAGAGTTCAGACTTAGGAGTAAAACAGAAAAGTGAACTAAACAGTCGCTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACA
ACTTGAACAAAGTGAAAAGGATTTGGTGAAACAGGCAAAGACCTTAAATAGTGCAGCAAATAAACTGATCCCAAAACATCATTAGGCATT
TTTAAGTTGGTCACGTCGCAAGTCCGATATCACAACTTAATTGTAAAAGGAAGAAATCTGAAAGTTACTACATTTAAGCTCTGATTCTAT
ATAAAATGTCACCAAAAAGTTGACTTTGAATTTGTTGGACTTTTAAAAAACCAGTTGGAAATATAGGTTGGGTTTTTTTCTTATTGTTTT
CTCCCCAGGGTTAGAAAAATTGGTATAAGTTCCTAATTAAAAGCTGAATAAACTTTGAGAAATTATTTCTGAGTTGACCAATAAATAAAA
ATACCACTTTCTTTAAAAAAGCCTAGGGAATTGAAGCTCTGTACATATACTAATGATGCCTTTACAACCCAGTCCTTGATAATACCAGAT
TCTCGGTGCATTGTTCATGTCTGTATCTGCAAGCCTGTTCTGCCATTGCAGTGTGATGAACCTAGAGGTAACTACCATGTGAACTTGAAC
TCTTCTAAAATAGTTCTGTGTCTCTTAGACCATGACCCCTTTTCACTTTTGTTATATAGGTTTAATCCCCAAGCCAAGGATAGTACTTAG
TATTTCACTACACTTCTATTCTCAGTAACCAAGATTGCTTGCAACTTTTTTTGCCTTGGTGACTTTTGAAAAAAAAAGAAAAGAAAAAGC
AGCATCCTTATATTTCTTTAAAATACATAGAAATAAAGTTAGTAATTAGGTAACCTATGATAACATAATAATGTGGACGCCTGGGGAAAC
CCTCCTCATGTTTGTCATCTTCTACCTCTGCCGTTTTCCTGCAATTCCGCTTCCTACTTAGGCAGTTCAGAGAGAACAATTCTAATAAAA
ACACTCCTCTCCTATTAACAAAAAATGATGCAGTACCCATTTTTCGTATCCTGCTTTTCTTATATTGGAGTAAAAAGGACAGGGTATAGA
CATGAATGATGATATTCTGCCTGGCCTGTCATTTCTTACCTGGAAACATTTACTTAAGAGTTTCTGTTACTTTTTGTTCAGATGGGGATT
TGCTAAAGGTTCTGGGAAGCTAATAATTGAATTATTAGAAAAACATTTCAGAATAGGAAGTAAATGATAAACTTATATTCTTTATTATTA
TTTAGTACAAAAATAGATTCCCAGTAGATATCCACAAGCAATATTAGCAGGGCTTCTGTTTCTAAGTGACCACAGACTAACCCTTTCTAG
GCTTTAACATTGTAAATAATCCTATAAACAGTTTGATTTTTTAAGATGATTTTTGATTTGAAGAGACAGGCTTTACATAAGCCTTCATTC
CTTCAAAAGGTCCTGACAAAATACTTGGGTTTTTTTCTCTTTTTTTCATTCTGGTATGCTTTGCAGCATTTCAGCTGCTTTGGTGGGGAC
ACAGATAACCCCTTCGCTTCCAGCTCTTAAAATTCTTTATCTTTTTCTTGGCAAAACCAGAATTAAGAGTGTAAGATAGATTCCATGTGT
GCTTATATAGGTCCCTGCACAGATTGGACTTGAACCAAAATTAAGTCCAAAGAACATATGTTTAGACCAACTTCATGGAAGTGGAAGATC
CTGTGCTCTTGAACTTATTTTAATTCTTATAATTTGCACCTATATAAACAAAGCTCCTACTGTATTCTTCTCTTCATCAACCTTTTGTGG
TGATGGGTTGCCTTTTCTACGAGCATTTGGAAGGAGTGATCAAATACCGAAATTGAACTTTCTAAAACCTACACATAGCATGCGTTTAAA
TTCTATTATATAAAGCCCCAAGTGCTTTACCTTCTAAAACATGCTTCTCTATAGGTGCAAAGTTATAAGATATGTAGAAGAAAACATCCA
TCAGAATCTTCTGGAGAATATGGTCAGAGTCTTAAACAGGCCCAGTGCTGAGTTCTTTGTCCACTTAGTCACACATCTTTTGTGGGAATG
GGAAAGGAAGGAGACAGCCAAACTCTGACAAAGGCTTTTCCTTATAGAATAACCCAAAGCCTAGGTGAGGGTTGATATATAATGTCCCAT
GATTTAATATATGTGGTTTGGGGGAAAGGACAAGAAAAAACTATAATTCCACATATAAGAAGGTAGTTGCCCATTTACAAGTTCCAGTTA
TGTGTGTAAAACAGAAAAATTAAGTACCAAACCTATTAGGAAATTTTTTTAAAAAGTGGATTTAACTTAAATTACTGTGTACTTGAGGTT
GGCTTTGGATATGGATTTTCTAAAAAGTGATGTTTTATTGTTTATCATCTAATGGCTGTAAACTGTAGTACTAGAATAAAAAAAATGGAA

>In-frame_ENST00000273854_ENST00000226328_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=877AA_start in transcript=601_stop in transcript=3234
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR

--------------------------------------------------------------
>In-frame_ENST00000273854_ENST00000536664_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=3273nt_BP=2003nt
TCCCTCCCCTCTTCAGCACTCAGCCCGCAGCTATTTCCTTCTGCCAGTCTCTTTGAACTCTGGATCTTTGCTTTTGCTCGCTGCTCTCCT
GTTTTTCATTCTCCACATTTTCTCAAGTCCTCTTTCTTTATCCTTAGCCACCCTGCTTTTTTCCTCCTTTTTTAAAAAATCGGAGATTTC
GTCTTAAAATGATTTGCCTTCCTTACCTTCGTCCATTTCAACACTGAAGGCTGCAAAGAACCTTCACCTTTCCCCTAGTGGTATTTAAAA
ATTCTCAATCCGTAAAAAGTCTTTTTGAAAGGCAAAGGAACAGGACCCAGGACCCTCTCGACACCCTTGATCCGAGTCCAGATCTGCACT
AGCAACCAGAACTAATATTTCATTTAACCCCACCAAAGGGGGAGGCGAGAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGT
GGTTCCTACATTTGGAGGAGCCGCGTGCCAGAAGGCGTAGGACCCCAAGGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTG
CGAGGCCGAAGCGGTGGACTGAGCCGCTCGGGACAGCGGCACCGGAGGAGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGG
ACGCCGGCGGCCCCCAAGCGGCGGCGGCGACACCCCCATCACCCCAGCGTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCT
CTGGACGTGCCTTCTCCTGTGCGCCGCACTCCGGACCCTCCTGGCCAGCCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCAT
GGGGGACCTGGGATGGATTGCTTTTCCAAAAAATGGGTGGGAAGAGATTGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCA
AGTATGCAAAGTGATGGAACAGAATCAGAATAACTGGCTTTTGACCAGTTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACT
CAAATTTACCCTGCGGGACTGCAACAGCCTTCCTGGAGGACTGGGGACCTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGA
TCAGAATGGGAGAAACATCAAGGAAAACCAATACATCAAAATTGATACCATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGA
CCGTGTTATGAAACTGAATACAGAGGTCAGAGATGTAGGACCTCTAAGCAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTG
CATTGCTCTGGTTTCTGTGCGTGTATACTATAAAAAATGCCCTTCTGTGGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGC
TGATTCTTCCCAATTGCTCGAAGTGTCAGGCTCCTGTGTCAACCATTCTGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGG
GGAGTGGCTGGTGCCCATCGGGAAATGCATGTGCAAGGCAGGATATGAAGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTT
CAAAGCCTCACCTCACATCCAGAGCTGCGGCAAATGTCCACCTCACAGTTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAA
GGATTATTTCAGGAGAGAGTCTGATCCACCCACAATGGCATGCACAAGACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGA
AACTAGTGTCTTTCTGGAATGGATTCCGCCTGCTGACACTGGTGGAAGGAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTC
CCATGCAGGTGTGTGTGAGGAGTGTGGCGGTCATGTCAGGTACCTTCCCCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGA
TCTACTCGCTCACACAAACTATACCTTTGAGATTGAGGCAGTGAATGGAGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGT
AAATGTAACCACAAATCAAGCAGATCCTAATTATCTCATGGCTAATGAACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGG
CTTGATTGAATCAGCTCTGAACCTGGGGAGGACTCTTGACTCTGACTATGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCT
GAAACATGGCTTGAAAGCTAAAAAAACTTTTCTCGGACAAAATAAATCCTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGA
AGCCGCAGAGATAACAGCAAGTGTTAAAGATCTTCCAGGACTTAAGACACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAAT
GCAAAAGAAACTTTCAGAATATATGAAAGCTTTGATCAATAAGAAAGAACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGA
AGAAGAAGGAGCCATAATTGCTGGTCTGTTGGTGGGTCTGAATGTCATTGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCA
GGTTGGAGTTATAGATTTTTCAATGTATCTCAAGGACGGGAACAGCAGTAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGA
CCAGAAGAACTATGTAGAAGAACTGAACAGACATTTGAATGCTACTGTAAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAA
CACTAAACTGACAGAGGAGCTTGCAGTTGCAAACAACAGGATCATTACCTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTA
CATACTGGAATCCAATCGGAAGGGTCCCAAGCAAGACAGAACTGCAGAAGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGA
GACACAATTACGATTGGATGTTGAGAAAGAACTGGAGATGCAGATCAGCATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAA
GGATGTCTGTGAGAAGCAGGATGCCCTGGTATCTCTTCGGCAGCAGCTGGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCT
GCAGAGTTCAGACTTAGGAGTAAAACAGAAAAGTGAACTAAACAGTCGCTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACA
ACTTGAACAAAGTGAAAAGGATTTGGTGAAACAGGCAAAGACCTTAAATAGTGCAGCAAATAAACTGATCCCAAAACATCATTAGGCATT

>In-frame_ENST00000273854_ENST00000536664_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=877AA_start in transcript=601_stop in transcript=3234
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR

--------------------------------------------------------------
>In-frame_ENST00000273854_ENST00000502653_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=4131nt_BP=2003nt
TCCCTCCCCTCTTCAGCACTCAGCCCGCAGCTATTTCCTTCTGCCAGTCTCTTTGAACTCTGGATCTTTGCTTTTGCTCGCTGCTCTCCT
GTTTTTCATTCTCCACATTTTCTCAAGTCCTCTTTCTTTATCCTTAGCCACCCTGCTTTTTTCCTCCTTTTTTAAAAAATCGGAGATTTC
GTCTTAAAATGATTTGCCTTCCTTACCTTCGTCCATTTCAACACTGAAGGCTGCAAAGAACCTTCACCTTTCCCCTAGTGGTATTTAAAA
ATTCTCAATCCGTAAAAAGTCTTTTTGAAAGGCAAAGGAACAGGACCCAGGACCCTCTCGACACCCTTGATCCGAGTCCAGATCTGCACT
AGCAACCAGAACTAATATTTCATTTAACCCCACCAAAGGGGGAGGCGAGAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGT
GGTTCCTACATTTGGAGGAGCCGCGTGCCAGAAGGCGTAGGACCCCAAGGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTG
CGAGGCCGAAGCGGTGGACTGAGCCGCTCGGGACAGCGGCACCGGAGGAGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGG
ACGCCGGCGGCCCCCAAGCGGCGGCGGCGACACCCCCATCACCCCAGCGTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCT
CTGGACGTGCCTTCTCCTGTGCGCCGCACTCCGGACCCTCCTGGCCAGCCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCAT
GGGGGACCTGGGATGGATTGCTTTTCCAAAAAATGGGTGGGAAGAGATTGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCA
AGTATGCAAAGTGATGGAACAGAATCAGAATAACTGGCTTTTGACCAGTTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACT
CAAATTTACCCTGCGGGACTGCAACAGCCTTCCTGGAGGACTGGGGACCTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGA
TCAGAATGGGAGAAACATCAAGGAAAACCAATACATCAAAATTGATACCATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGA
CCGTGTTATGAAACTGAATACAGAGGTCAGAGATGTAGGACCTCTAAGCAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTG
CATTGCTCTGGTTTCTGTGCGTGTATACTATAAAAAATGCCCTTCTGTGGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGC
TGATTCTTCCCAATTGCTCGAAGTGTCAGGCTCCTGTGTCAACCATTCTGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGG
GGAGTGGCTGGTGCCCATCGGGAAATGCATGTGCAAGGCAGGATATGAAGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTT
CAAAGCCTCACCTCACATCCAGAGCTGCGGCAAATGTCCACCTCACAGTTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAA
GGATTATTTCAGGAGAGAGTCTGATCCACCCACAATGGCATGCACAAGACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGA
AACTAGTGTCTTTCTGGAATGGATTCCGCCTGCTGACACTGGTGGAAGGAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTC
CCATGCAGGTGTGTGTGAGGAGTGTGGCGGTCATGTCAGGTACCTTCCCCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGA
TCTACTCGCTCACACAAACTATACCTTTGAGATTGAGGCAGTGAATGGAGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGT
AAATGTAACCACAAATCAAGCAGATCCTAATTATCTCATGGCTAATGAACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGG
CTTGATTGAATCAGCTCTGAACCTGGGGAGGACTCTTGACTCTGACTATGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCT
GAAACATGGCTTGAAAGCTAAAAAAACTTTTCTCGGACAAAATAAATCCTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGA
AGCCGCAGAGATAACAGCAAGTGTTAAAGATCTTCCAGGACTTAAGACACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAAT
GCAAAAGAAACTTTCAGAATATATGAAAGCTTTGATCAATAAGAAAGAACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGA
AGAAGAAGGAGCCATAATTGCTGGTCTGTTGGTGGGTCTGAATGTCATTGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCA
GGTTGGAGTTATAGATTTTTCAATGTATCTCAAGGACGGGAACAGCAGTAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGA
CCAGAAGAACTATGTAGAAGAACTGAACAGACATTTGAATGCTACTGTAAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAA
CACTAAACTGACAGAGGAGCTTGCAGTTGCAAACAACAGGATCATTACCTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTA
CATACTGGAATCCAATCGGAAGGGTCCCAAGCAAGACAGAACTGCAGAAGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGA
GACACAATTACGATTGGATGTTGAGAAAGAACTGGAGATGCAGATCAGCATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAA
GGATGTCTGTGAGAAGCAGGATGCCCTGGTATCTCTTCGGCAGCAGCTGGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCT
GCAGAGTTCAGACTTAGGAGTAAAACAGAAAAGTGAACTAAACAGTCGCTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACA
ACTTGAACAAAGATTGCGCCAGGCTGAGCGAAGCCGCCAATCTGCTGAGTTGGACAACCGGCTCTTCAAACAGGACTTTGGAGACAAGAT
CAACAGTCTGCAGCTGGAAGTCGAGGAGCTCACCAGGCAGCGGAACCAGCTTGAGTTAGAACTAAAACAGGAAAAAGAAAGAAGATTACA
AAACGACAGGAGCATCCCAGGAAGGGGTTCCCAGAAGTCAGAATCCAAGATGGATGGGAAGCACAAAATGCAAGAGGAAAATGTTAAACT
AAAAAAGCCCCTGGAAGAAAGCCACAGGCTGCAACCCCACCCTATGGATGAACAGGATCAGCTGCTGCTCTCTGAAAAGCCACAGTTGTG
TCAGCTATGCCAGGAAGACGGCAGCCTAACAAAGAATGTGTGTAAGAACTGCAGCGGAACCTTCTGTGATGCCTGTTCAACAAATGAACT
GCCTCTTCCTTCAAGTATCAAGCTTGAGCGAGTTTGCAATCCCTGTCACAAGCATCTGATGAAGCAATATTCTACCAGCCCATCATAAGA
CTGGAGGCCAAGACCTGGACCAAAACGTTTATGCAGGCTCCTCTGTACCTGTGTTTTAGCTGTCAGGATCTCATAGAGCCCAGTTCTTAG
AGTCAACTAAAGAGTTGATAGGAATTTACTAGGTCCAGGGAGAAAAGGCAGTGGTTGGGGTTACTGGAAATTTTGCTCATTTTCTCTAAT
GACTGTATGAATAAAAGTGAACTTACTTGAGCCTTTCTCTTCTAAATCTAAACAACCTGATATTGAAGGTTTGCTTTATAGCATATCTTT
GGAAAGGCAACTCATTTTTATGATTAGTGATACTGGGGTGGATTTAATAGGAGAGAGAATCCAGGCAGATAAGAATAAAAAGGAAAATGA

>In-frame_ENST00000273854_ENST00000502653_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=1028AA_start in transcript=601_stop in transcript=3687
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR
ALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNRLFKQDFGDKINSLQLEVEELTRQRNQLELE
LKQEKERRLQNDRSIPGRGSQKSESKMDGKHKMQEENVKLKKPLEESHRLQPHPMDEQDQLLLSEKPQLCQLCQEDGSLTKNVCKNCSGT

--------------------------------------------------------------
>In-frame_ENST00000354839_ENST00000417478_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=3244nt_BP=1595nt
GAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGTGGTTCCTACATTTGGAGGAGCCGCGTGCCAGAAGGCGTAGGACCCCAA
GGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTGCGAGGCCGAAGCGGTGGACTGAGCCGCTCGGGACAGCGGCACCGGAGG
AGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGGACGCCGGCGGCCCCCAAGCGGCGGCGGCGACACCCCCATCACCCCAGC
GTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCTCTGGACGTGCCTTCTCCTGTGCGCCGCACTCCGGACCCTCCTGGCCAG
CCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCATGGGGGACCTGGGATGGATTGCTTTTCCAAAAAATGGGTGGGAAGAGAT
TGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCAAGTATGCAAAGTGATGGAACAGAATCAGAATAACTGGCTTTTGACCAG
TTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACTCAAATTTACCCTGCGGGACTGCAACAGCCTTCCTGGAGGACTGGGGAC
CTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGATCAGAATGGGAGAAACATCAAGGAAAACCAATACATCAAAATTGATAC
CATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGACCGTGTTATGAAACTGAATACAGAGGTCAGAGATGTAGGACCTCTAAG
CAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTGCATTGCTCTGGTTTCTGTGCGTGTATACTATAAAAAATGCCCTTCTGT
GGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGCTGATTCTTCCCAATTGCTCGAAGTGTCAGGCTCCTGTGTCAACCATTC
TGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGGGGAGTGGCTGGTGCCCATCGGGAAATGCATGTGCAAGGCAGGATATGA
AGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTTCAAAGCCTCACCTCACATCCAGAGCTGCGGCAAATGTCCACCTCACAG
TTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAAGGATTATTTCAGGAGAGAGTCTGATCCACCCACAATGGCATGCACAAG
ACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGAAACTAGTGTCTTTCTGGAATGGATTCCGCCTGCTGACACTGGTGGAAG
GAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTCCCATGCAGGTGTGTGTGAGGAGTGTGGCGGTCATGTCAGGTACCTTCC
CCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGATCTACTCGCTCACACAAACTATACCTTTGAGATTGAGGCAGTGAATGG
AGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGTAAATGTAACCACAAATCAAGCAGATCCTAATTATCTCATGGCTAATGA
ACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGGCTTGATTGAATCAGCTCTGAACCTGGGGAGGACTCTTGACTCTGACTA
TGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCTGAAACATGGCTTGAAAGCTAAAAAAACTTTTCTCGGACAAAATAAATC
CTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGAAGCCGCAGAGATAACAGCAAGTGTTAAAGATCTTCCAGGACTTAAGAC
ACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAATGCAAAAGAAACTTTCAGAATATATGAAAGCTTTGATCAATAAGAAAGA
ACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGAAGAAGAAGGAGCCATAATTGCTGGTCTGTTGGTGGGTCTGAATGTCAT
TGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCAGGTTGGAGTTATAGATTTTTCAATGTATCTCAAGGACGGGAACAGCAG
TAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGACCAGAAGAACTATGTAGAAGAACTGAACAGACATTTGAATGCTACTGT
AAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAACACTAAACTGACAGAGGAGCTTGCAGTTGCAAACAACAGGATCATTAC
CTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTACATACTGGAATCCAATCGGAAGGGTCCCAAGCAAGACAGAACTGCAGA
AGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGAGACACAATTACGATTGGATGTTGAGAAAGAACTGGAGATGCAGATCAG
CATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAAGGATGTCTGTGAGAAGCAGGATGCCCTGGTATCTCTTCGGCAGCAGCT
GGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCTGCAGAGTTCAGACTTAGGAGTAAAACAGAAAAGTGAACTAAACAGTCG
CTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACAACTTGAACAAAGGTAAAAGTCCTGTTTCTTTAATGAAACACTTTGGAT
TGTCAGTGCTGAAGTGAAAAGAATGTGCTGTACATTCGGCAAATAGAAAATACATGAAATTCTTCCAAATTAGCATCAGACATTCTGGTA
GAAAAAAGCCAGTTGAATGTTATGTGTGTTTTCTAAGGTATGACTGAAATGTTTTTAGGAAATGTCAATCACTTGACTAGCCTTTAAAAA
AAAAAAAGAAAGGTCAGCCTTTTATGACTGTTTTGAACATCAGAACTCTTAATCCATGTCAGAGTCATGTGTTAGAGGAAGGATACTTAA
AAGCATGGAAGGACTCTTAAATGTATGTATGTAATTCTGTGATTTTATTGTTCATCACTGAAGTCTTTGAATACTTGGATGCTAGGGGAT
ATAGAGGCACTGAGAGATAGGTGTCCTCCAAGGATCTATTCTGGATCTTTCTCTCCCTTCTTTAACCCTTTTCTCTTATCTCCCTTTTCT

>In-frame_ENST00000354839_ENST00000417478_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=854AA_start in transcript=193_stop in transcript=2757
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR

--------------------------------------------------------------
>In-frame_ENST00000354839_ENST00000381006_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=3936nt_BP=1595nt
GAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGTGGTTCCTACATTTGGAGGAGCCGCGTGCCAGAAGGCGTAGGACCCCAA
GGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTGCGAGGCCGAAGCGGTGGACTGAGCCGCTCGGGACAGCGGCACCGGAGG
AGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGGACGCCGGCGGCCCCCAAGCGGCGGCGGCGACACCCCCATCACCCCAGC
GTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCTCTGGACGTGCCTTCTCCTGTGCGCCGCACTCCGGACCCTCCTGGCCAG
CCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCATGGGGGACCTGGGATGGATTGCTTTTCCAAAAAATGGGTGGGAAGAGAT
TGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCAAGTATGCAAAGTGATGGAACAGAATCAGAATAACTGGCTTTTGACCAG
TTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACTCAAATTTACCCTGCGGGACTGCAACAGCCTTCCTGGAGGACTGGGGAC
CTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGATCAGAATGGGAGAAACATCAAGGAAAACCAATACATCAAAATTGATAC
CATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGACCGTGTTATGAAACTGAATACAGAGGTCAGAGATGTAGGACCTCTAAG
CAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTGCATTGCTCTGGTTTCTGTGCGTGTATACTATAAAAAATGCCCTTCTGT
GGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGCTGATTCTTCCCAATTGCTCGAAGTGTCAGGCTCCTGTGTCAACCATTC
TGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGGGGAGTGGCTGGTGCCCATCGGGAAATGCATGTGCAAGGCAGGATATGA
AGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTTCAAAGCCTCACCTCACATCCAGAGCTGCGGCAAATGTCCACCTCACAG
TTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAAGGATTATTTCAGGAGAGAGTCTGATCCACCCACAATGGCATGCACAAG
ACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGAAACTAGTGTCTTTCTGGAATGGATTCCGCCTGCTGACACTGGTGGAAG
GAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTCCCATGCAGGTGTGTGTGAGGAGTGTGGCGGTCATGTCAGGTACCTTCC
CCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGATCTACTCGCTCACACAAACTATACCTTTGAGATTGAGGCAGTGAATGG
AGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGTAAATGTAACCACAAATCAAGCAGATCCTAATTATCTCATGGCTAATGA
ACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGGCTTGATTGAATCAGCTCTGAACCTGGGGAGGACTCTTGACTCTGACTA
TGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCTGAAACATGGCTTGAAAGCTAAAAAAACTTTTCTCGGACAAAATAAATC
CTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGAAGCCGCAGAGATAACAGCAAGTGTTAAAGATCTTCCAGGACTTAAGAC
ACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAATGCAAAAGAAACTTTCAGAATATATGAAAGCTTTGATCAATAAGAAAGA
ACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGAAGAAGAAGGAGCCATAATTGCTGGTCTGTTGGTGGGTCTGAATGTCAT
TGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCAGGTTGGAGTTATAGATTTTTCAATGTATCTCAAGGACGGGAACAGCAG
TAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGACCAGAAGAACTATGTAGAAGAACTGAACAGACATTTGAATGCTACTGT
AAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAACACTAAACTGACAGAGGAGCTTGCAGTTGCAAACAACAGGATCATTAC
CTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTACATACTGGAATCCAATCGGAAGGGTCCCAAGCAAGACAGAACTGCAGA
AGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGAGACACAATTACGATTGGATGTTGAGAAAGAACTGGAGATGCAGATCAG
CATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAAGGATGTCTGTGAGAAGCAGGATGCCCTGGTATCTCTTCGGCAGCAGCT
GGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCTGCAGAGTTCAGACTTAGGAGTAAAACAGAAAAGTGAACTAAACAGTCG
CTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACAACTTGAACAAAGATTGCGCCAGGCTGAGCGAAGCCGCCAATCTGCTGA
GTTGGACAACCGGCTCTTCAAACAGGACTTTGGAGACAAGATCAACAGTCTGCAGCTGGAAGTCGAGGAGCTCACCAGGCAGCGGAACCA
GCTTGAGTTAGAACTAAAACAGGAAAAAGAAAGAAGATTACAAAACGACAGGAGCATCCCAGGAAGGGGTTCCCAGAAGTCAGAATCCAA
GATGGATGGGAAGCACAAAATGCAAGAGGAAAATGTTAAACTAAAAAAGCCCCTGGAAGAAAGCCACAGGCTGCAACCCCACCCTATGGA
TGAACAGGATCAGCTGCTGCTCTCTGAAAAGCCACAGTTGTGTCAGCTATGCCAGGAAGACGGCAGCCTAACAAAGAATGTGTGTAAGAA
CTGCAGCGGAACCTTCTGTGATGCCTGTTCAACAAATGAACTGCCTCTTCCTTCAAGTATCAAGCTTGAGCGAGTTTGCAATCCCTGTCA
CAAGCATCTGATGAAGCAATATTCTACCAGCCCATCATAAGACTGGAGGCCAAGACCTGGACCAAAACGTTTATGCAGGCTCCTCTGTAC
CTGTGTTTTAGCTGTCAGGATCTCATAGAGCCCAGTTCTTAGAGTCAACTAAAGAGTTGATAGGAATTTACTAGGTCCAGGGAGAAAAGG
CAGTGGTTGGGGTTACTGGAAATTTTGCTCATTTTCTCTAATGACTGTATGAATAAAAGTGAACTTACTTGAGCCTTTCTCTTCTAAATC
TAAACAACCTGATATTGAAGGTTTGCTTTATAGCATATCTTTGGAAAGGCAACTCATTTTTATGATTAGTGATACTGGGGTGGATTTAAT
AGGAGAGAGAATCCAGGCAGATAAGAATAAAAAGGAAAATGATCATCTCCTTCTATAGCATTTGCAGATTCAAGGGGGAGAGGTAGATGC
TGAGATCAAAATGACAGTTGTTACTTATTTTTCCAGGTGCTGTTAGTATAAACATTGTTTCCTCTTCACCCCTGCTAACTACCTCTTTAA
AGTATTTCTACCAAACTGTGAACCCAATCTCAGGGAAAAGAAATTAAAAAGTAATATAAATTCTGCATATATTAAAAACAATATTGTAAT

>In-frame_ENST00000354839_ENST00000381006_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=1028AA_start in transcript=193_stop in transcript=3279
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR
ALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNRLFKQDFGDKINSLQLEVEELTRQRNQLELE
LKQEKERRLQNDRSIPGRGSQKSESKMDGKHKMQEENVKLKKPLEESHRLQPHPMDEQDQLLLSEKPQLCQLCQEDGSLTKNVCKNCSGT

--------------------------------------------------------------
>In-frame_ENST00000354839_ENST00000226328_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=5087nt_BP=1595nt
GAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGTGGTTCCTACATTTGGAGGAGCCGCGTGCCAGAAGGCGTAGGACCCCAA
GGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTGCGAGGCCGAAGCGGTGGACTGAGCCGCTCGGGACAGCGGCACCGGAGG
AGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGGACGCCGGCGGCCCCCAAGCGGCGGCGGCGACACCCCCATCACCCCAGC
GTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCTCTGGACGTGCCTTCTCCTGTGCGCCGCACTCCGGACCCTCCTGGCCAG
CCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCATGGGGGACCTGGGATGGATTGCTTTTCCAAAAAATGGGTGGGAAGAGAT
TGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCAAGTATGCAAAGTGATGGAACAGAATCAGAATAACTGGCTTTTGACCAG
TTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACTCAAATTTACCCTGCGGGACTGCAACAGCCTTCCTGGAGGACTGGGGAC
CTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGATCAGAATGGGAGAAACATCAAGGAAAACCAATACATCAAAATTGATAC
CATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGACCGTGTTATGAAACTGAATACAGAGGTCAGAGATGTAGGACCTCTAAG
CAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTGCATTGCTCTGGTTTCTGTGCGTGTATACTATAAAAAATGCCCTTCTGT
GGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGCTGATTCTTCCCAATTGCTCGAAGTGTCAGGCTCCTGTGTCAACCATTC
TGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGGGGAGTGGCTGGTGCCCATCGGGAAATGCATGTGCAAGGCAGGATATGA
AGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTTCAAAGCCTCACCTCACATCCAGAGCTGCGGCAAATGTCCACCTCACAG
TTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAAGGATTATTTCAGGAGAGAGTCTGATCCACCCACAATGGCATGCACAAG
ACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGAAACTAGTGTCTTTCTGGAATGGATTCCGCCTGCTGACACTGGTGGAAG
GAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTCCCATGCAGGTGTGTGTGAGGAGTGTGGCGGTCATGTCAGGTACCTTCC
CCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGATCTACTCGCTCACACAAACTATACCTTTGAGATTGAGGCAGTGAATGG
AGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGTAAATGTAACCACAAATCAAGCAGATCCTAATTATCTCATGGCTAATGA
ACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGGCTTGATTGAATCAGCTCTGAACCTGGGGAGGACTCTTGACTCTGACTA
TGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCTGAAACATGGCTTGAAAGCTAAAAAAACTTTTCTCGGACAAAATAAATC
CTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGAAGCCGCAGAGATAACAGCAAGTGTTAAAGATCTTCCAGGACTTAAGAC
ACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAATGCAAAAGAAACTTTCAGAATATATGAAAGCTTTGATCAATAAGAAAGA
ACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGAAGAAGAAGGAGCCATAATTGCTGGTCTGTTGGTGGGTCTGAATGTCAT
TGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCAGGTTGGAGTTATAGATTTTTCAATGTATCTCAAGGACGGGAACAGCAG
TAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGACCAGAAGAACTATGTAGAAGAACTGAACAGACATTTGAATGCTACTGT
AAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAACACTAAACTGACAGAGGAGCTTGCAGTTGCAAACAACAGGATCATTAC
CTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTACATACTGGAATCCAATCGGAAGGGTCCCAAGCAAGACAGAACTGCAGA
AGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGAGACACAATTACGATTGGATGTTGAGAAAGAACTGGAGATGCAGATCAG
CATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAAGGATGTCTGTGAGAAGCAGGATGCCCTGGTATCTCTTCGGCAGCAGCT
GGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCTGCAGAGTTCAGACTTAGGAGTAAAACAGAAAAGTGAACTAAACAGTCG
CTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACAACTTGAACAAAGTGAAAAGGATTTGGTGAAACAGGCAAAGACCTTAAA
TAGTGCAGCAAATAAACTGATCCCAAAACATCATTAGGCATTTTTAAGTTGGTCACGTCGCAAGTCCGATATCACAACTTAATTGTAAAA
GGAAGAAATCTGAAAGTTACTACATTTAAGCTCTGATTCTATATAAAATGTCACCAAAAAGTTGACTTTGAATTTGTTGGACTTTTAAAA
AACCAGTTGGAAATATAGGTTGGGTTTTTTTCTTATTGTTTTCTCCCCAGGGTTAGAAAAATTGGTATAAGTTCCTAATTAAAAGCTGAA
TAAACTTTGAGAAATTATTTCTGAGTTGACCAATAAATAAAAATACCACTTTCTTTAAAAAAGCCTAGGGAATTGAAGCTCTGTACATAT
ACTAATGATGCCTTTACAACCCAGTCCTTGATAATACCAGATTCTCGGTGCATTGTTCATGTCTGTATCTGCAAGCCTGTTCTGCCATTG
CAGTGTGATGAACCTAGAGGTAACTACCATGTGAACTTGAACTCTTCTAAAATAGTTCTGTGTCTCTTAGACCATGACCCCTTTTCACTT
TTGTTATATAGGTTTAATCCCCAAGCCAAGGATAGTACTTAGTATTTCACTACACTTCTATTCTCAGTAACCAAGATTGCTTGCAACTTT
TTTTGCCTTGGTGACTTTTGAAAAAAAAAGAAAAGAAAAAGCAGCATCCTTATATTTCTTTAAAATACATAGAAATAAAGTTAGTAATTA
GGTAACCTATGATAACATAATAATGTGGACGCCTGGGGAAACCCTCCTCATGTTTGTCATCTTCTACCTCTGCCGTTTTCCTGCAATTCC
GCTTCCTACTTAGGCAGTTCAGAGAGAACAATTCTAATAAAAACACTCCTCTCCTATTAACAAAAAATGATGCAGTACCCATTTTTCGTA
TCCTGCTTTTCTTATATTGGAGTAAAAAGGACAGGGTATAGACATGAATGATGATATTCTGCCTGGCCTGTCATTTCTTACCTGGAAACA
TTTACTTAAGAGTTTCTGTTACTTTTTGTTCAGATGGGGATTTGCTAAAGGTTCTGGGAAGCTAATAATTGAATTATTAGAAAAACATTT
CAGAATAGGAAGTAAATGATAAACTTATATTCTTTATTATTATTTAGTACAAAAATAGATTCCCAGTAGATATCCACAAGCAATATTAGC
AGGGCTTCTGTTTCTAAGTGACCACAGACTAACCCTTTCTAGGCTTTAACATTGTAAATAATCCTATAAACAGTTTGATTTTTTAAGATG
ATTTTTGATTTGAAGAGACAGGCTTTACATAAGCCTTCATTCCTTCAAAAGGTCCTGACAAAATACTTGGGTTTTTTTCTCTTTTTTTCA
TTCTGGTATGCTTTGCAGCATTTCAGCTGCTTTGGTGGGGACACAGATAACCCCTTCGCTTCCAGCTCTTAAAATTCTTTATCTTTTTCT
TGGCAAAACCAGAATTAAGAGTGTAAGATAGATTCCATGTGTGCTTATATAGGTCCCTGCACAGATTGGACTTGAACCAAAATTAAGTCC
AAAGAACATATGTTTAGACCAACTTCATGGAAGTGGAAGATCCTGTGCTCTTGAACTTATTTTAATTCTTATAATTTGCACCTATATAAA
CAAAGCTCCTACTGTATTCTTCTCTTCATCAACCTTTTGTGGTGATGGGTTGCCTTTTCTACGAGCATTTGGAAGGAGTGATCAAATACC
GAAATTGAACTTTCTAAAACCTACACATAGCATGCGTTTAAATTCTATTATATAAAGCCCCAAGTGCTTTACCTTCTAAAACATGCTTCT
CTATAGGTGCAAAGTTATAAGATATGTAGAAGAAAACATCCATCAGAATCTTCTGGAGAATATGGTCAGAGTCTTAAACAGGCCCAGTGC
TGAGTTCTTTGTCCACTTAGTCACACATCTTTTGTGGGAATGGGAAAGGAAGGAGACAGCCAAACTCTGACAAAGGCTTTTCCTTATAGA
ATAACCCAAAGCCTAGGTGAGGGTTGATATATAATGTCCCATGATTTAATATATGTGGTTTGGGGGAAAGGACAAGAAAAAACTATAATT
CCACATATAAGAAGGTAGTTGCCCATTTACAAGTTCCAGTTATGTGTGTAAAACAGAAAAATTAAGTACCAAACCTATTAGGAAATTTTT
TTAAAAAGTGGATTTAACTTAAATTACTGTGTACTTGAGGTTGGCTTTGGATATGGATTTTCTAAAAAGTGATGTTTTATTGTTTATCAT

>In-frame_ENST00000354839_ENST00000226328_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=877AA_start in transcript=193_stop in transcript=2826
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR

--------------------------------------------------------------
>In-frame_ENST00000354839_ENST00000536664_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=2865nt_BP=1595nt
GAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGTGGTTCCTACATTTGGAGGAGCCGCGTGCCAGAAGGCGTAGGACCCCAA
GGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTGCGAGGCCGAAGCGGTGGACTGAGCCGCTCGGGACAGCGGCACCGGAGG
AGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGGACGCCGGCGGCCCCCAAGCGGCGGCGGCGACACCCCCATCACCCCAGC
GTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCTCTGGACGTGCCTTCTCCTGTGCGCCGCACTCCGGACCCTCCTGGCCAG
CCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCATGGGGGACCTGGGATGGATTGCTTTTCCAAAAAATGGGTGGGAAGAGAT
TGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCAAGTATGCAAAGTGATGGAACAGAATCAGAATAACTGGCTTTTGACCAG
TTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACTCAAATTTACCCTGCGGGACTGCAACAGCCTTCCTGGAGGACTGGGGAC
CTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGATCAGAATGGGAGAAACATCAAGGAAAACCAATACATCAAAATTGATAC
CATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGACCGTGTTATGAAACTGAATACAGAGGTCAGAGATGTAGGACCTCTAAG
CAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTGCATTGCTCTGGTTTCTGTGCGTGTATACTATAAAAAATGCCCTTCTGT
GGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGCTGATTCTTCCCAATTGCTCGAAGTGTCAGGCTCCTGTGTCAACCATTC
TGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGGGGAGTGGCTGGTGCCCATCGGGAAATGCATGTGCAAGGCAGGATATGA
AGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTTCAAAGCCTCACCTCACATCCAGAGCTGCGGCAAATGTCCACCTCACAG
TTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAAGGATTATTTCAGGAGAGAGTCTGATCCACCCACAATGGCATGCACAAG
ACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGAAACTAGTGTCTTTCTGGAATGGATTCCGCCTGCTGACACTGGTGGAAG
GAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTCCCATGCAGGTGTGTGTGAGGAGTGTGGCGGTCATGTCAGGTACCTTCC
CCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGATCTACTCGCTCACACAAACTATACCTTTGAGATTGAGGCAGTGAATGG
AGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGTAAATGTAACCACAAATCAAGCAGATCCTAATTATCTCATGGCTAATGA
ACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGGCTTGATTGAATCAGCTCTGAACCTGGGGAGGACTCTTGACTCTGACTA
TGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCTGAAACATGGCTTGAAAGCTAAAAAAACTTTTCTCGGACAAAATAAATC
CTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGAAGCCGCAGAGATAACAGCAAGTGTTAAAGATCTTCCAGGACTTAAGAC
ACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAATGCAAAAGAAACTTTCAGAATATATGAAAGCTTTGATCAATAAGAAAGA
ACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGAAGAAGAAGGAGCCATAATTGCTGGTCTGTTGGTGGGTCTGAATGTCAT
TGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCAGGTTGGAGTTATAGATTTTTCAATGTATCTCAAGGACGGGAACAGCAG
TAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGACCAGAAGAACTATGTAGAAGAACTGAACAGACATTTGAATGCTACTGT
AAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAACACTAAACTGACAGAGGAGCTTGCAGTTGCAAACAACAGGATCATTAC
CTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTACATACTGGAATCCAATCGGAAGGGTCCCAAGCAAGACAGAACTGCAGA
AGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGAGACACAATTACGATTGGATGTTGAGAAAGAACTGGAGATGCAGATCAG
CATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAAGGATGTCTGTGAGAAGCAGGATGCCCTGGTATCTCTTCGGCAGCAGCT
GGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCTGCAGAGTTCAGACTTAGGAGTAAAACAGAAAAGTGAACTAAACAGTCG
CTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACAACTTGAACAAAGTGAAAAGGATTTGGTGAAACAGGCAAAGACCTTAAA

>In-frame_ENST00000354839_ENST00000536664_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=877AA_start in transcript=193_stop in transcript=2826
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR

--------------------------------------------------------------
>In-frame_ENST00000354839_ENST00000502653_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=3723nt_BP=1595nt
GAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGTGGTTCCTACATTTGGAGGAGCCGCGTGCCAGAAGGCGTAGGACCCCAA
GGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTGCGAGGCCGAAGCGGTGGACTGAGCCGCTCGGGACAGCGGCACCGGAGG
AGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGGACGCCGGCGGCCCCCAAGCGGCGGCGGCGACACCCCCATCACCCCAGC
GTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCTCTGGACGTGCCTTCTCCTGTGCGCCGCACTCCGGACCCTCCTGGCCAG
CCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCATGGGGGACCTGGGATGGATTGCTTTTCCAAAAAATGGGTGGGAAGAGAT
TGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCAAGTATGCAAAGTGATGGAACAGAATCAGAATAACTGGCTTTTGACCAG
TTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACTCAAATTTACCCTGCGGGACTGCAACAGCCTTCCTGGAGGACTGGGGAC
CTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGATCAGAATGGGAGAAACATCAAGGAAAACCAATACATCAAAATTGATAC
CATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGACCGTGTTATGAAACTGAATACAGAGGTCAGAGATGTAGGACCTCTAAG
CAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTGCATTGCTCTGGTTTCTGTGCGTGTATACTATAAAAAATGCCCTTCTGT
GGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGCTGATTCTTCCCAATTGCTCGAAGTGTCAGGCTCCTGTGTCAACCATTC
TGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGGGGAGTGGCTGGTGCCCATCGGGAAATGCATGTGCAAGGCAGGATATGA
AGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTTCAAAGCCTCACCTCACATCCAGAGCTGCGGCAAATGTCCACCTCACAG
TTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAAGGATTATTTCAGGAGAGAGTCTGATCCACCCACAATGGCATGCACAAG
ACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGAAACTAGTGTCTTTCTGGAATGGATTCCGCCTGCTGACACTGGTGGAAG
GAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTCCCATGCAGGTGTGTGTGAGGAGTGTGGCGGTCATGTCAGGTACCTTCC
CCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGATCTACTCGCTCACACAAACTATACCTTTGAGATTGAGGCAGTGAATGG
AGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGTAAATGTAACCACAAATCAAGCAGATCCTAATTATCTCATGGCTAATGA
ACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGGCTTGATTGAATCAGCTCTGAACCTGGGGAGGACTCTTGACTCTGACTA
TGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCTGAAACATGGCTTGAAAGCTAAAAAAACTTTTCTCGGACAAAATAAATC
CTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGAAGCCGCAGAGATAACAGCAAGTGTTAAAGATCTTCCAGGACTTAAGAC
ACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAATGCAAAAGAAACTTTCAGAATATATGAAAGCTTTGATCAATAAGAAAGA
ACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGAAGAAGAAGGAGCCATAATTGCTGGTCTGTTGGTGGGTCTGAATGTCAT
TGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCAGGTTGGAGTTATAGATTTTTCAATGTATCTCAAGGACGGGAACAGCAG
TAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGACCAGAAGAACTATGTAGAAGAACTGAACAGACATTTGAATGCTACTGT
AAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAACACTAAACTGACAGAGGAGCTTGCAGTTGCAAACAACAGGATCATTAC
CTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTACATACTGGAATCCAATCGGAAGGGTCCCAAGCAAGACAGAACTGCAGA
AGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGAGACACAATTACGATTGGATGTTGAGAAAGAACTGGAGATGCAGATCAG
CATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAAGGATGTCTGTGAGAAGCAGGATGCCCTGGTATCTCTTCGGCAGCAGCT
GGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCTGCAGAGTTCAGACTTAGGAGTAAAACAGAAAAGTGAACTAAACAGTCG
CTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACAACTTGAACAAAGATTGCGCCAGGCTGAGCGAAGCCGCCAATCTGCTGA
GTTGGACAACCGGCTCTTCAAACAGGACTTTGGAGACAAGATCAACAGTCTGCAGCTGGAAGTCGAGGAGCTCACCAGGCAGCGGAACCA
GCTTGAGTTAGAACTAAAACAGGAAAAAGAAAGAAGATTACAAAACGACAGGAGCATCCCAGGAAGGGGTTCCCAGAAGTCAGAATCCAA
GATGGATGGGAAGCACAAAATGCAAGAGGAAAATGTTAAACTAAAAAAGCCCCTGGAAGAAAGCCACAGGCTGCAACCCCACCCTATGGA
TGAACAGGATCAGCTGCTGCTCTCTGAAAAGCCACAGTTGTGTCAGCTATGCCAGGAAGACGGCAGCCTAACAAAGAATGTGTGTAAGAA
CTGCAGCGGAACCTTCTGTGATGCCTGTTCAACAAATGAACTGCCTCTTCCTTCAAGTATCAAGCTTGAGCGAGTTTGCAATCCCTGTCA
CAAGCATCTGATGAAGCAATATTCTACCAGCCCATCATAAGACTGGAGGCCAAGACCTGGACCAAAACGTTTATGCAGGCTCCTCTGTAC
CTGTGTTTTAGCTGTCAGGATCTCATAGAGCCCAGTTCTTAGAGTCAACTAAAGAGTTGATAGGAATTTACTAGGTCCAGGGAGAAAAGG
CAGTGGTTGGGGTTACTGGAAATTTTGCTCATTTTCTCTAATGACTGTATGAATAAAAGTGAACTTACTTGAGCCTTTCTCTTCTAAATC
TAAACAACCTGATATTGAAGGTTTGCTTTATAGCATATCTTTGGAAAGGCAACTCATTTTTATGATTAGTGATACTGGGGTGGATTTAAT
AGGAGAGAGAATCCAGGCAGATAAGAATAAAAAGGAAAATGATCATCTCCTTCTATAGCATTTGCAGATTCAAGGGGGAGAGGTAGATGC

>In-frame_ENST00000354839_ENST00000502653_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=1028AA_start in transcript=193_stop in transcript=3279
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR
ALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNRLFKQDFGDKINSLQLEVEELTRQRNQLELE
LKQEKERRLQNDRSIPGRGSQKSESKMDGKHKMQEENVKLKKPLEESHRLQPHPMDEQDQLLLSEKPQLCQLCQEDGSLTKNVCKNCSGT

--------------------------------------------------------------
>In-frame_ENST00000511294_ENST00000417478_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=3804nt_BP=2155nt
CCAGACACAGCAGGAGCGCGCCTTGGCGGTGCAGTTTCAACCTCGACTTCGCAGCCGCGCACACACCGCCTGCTCCCCGAGCAGCGGGAA
CCGCAGCAGCTCCTGGGCCGCCGCAGCGCAGCTCCGCGCTCCTACCGGCCGGCAGCCGTCAGTCCCTCCCCTCTTCAGCACTCAGCCCGC
AGCTATTTCCTTCTGCCAGTCTCTTTGAACTCTGGATCTTTGCTTTTGCTCGCTGCTCTCCTGTTTTTCATTCTCCACATTTTCTCAAGT
CCTCTTTCTTTATCCTTAGCCACCCTGCTTTTTTCCTCCTTTTTTAAAAAATCGGAGATTTCGTCTTAAAATGATTTGCCTTCCTTACCT
TCGTCCATTTCAACACTGAAGGCTGCAAAGAACCTTCACCTTTCCCCTAGTGGTATTTAAAAATTCTCAATCCGTAAAAAGTCTTTTTGA
AAGGCAAAGGAACAGGACCCAGGACCCTCTCGACACCCTTGATCCGAGTCCAGATCTGCACTAGCAACCAGAACTAATATTTCATTTAAC
CCCACCAAAGGGGGAGGCGAGAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGTGGTTCCTACATTTGGAGGAGCCGCGTGC
CAGAAGGCGTAGGACCCCAAGGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTGCGAGGCCGAAGCGGTGGACTGAGCCGCT
CGGGACAGCGGCACCGGAGGAGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGGACGCCGGCGGCCCCCAAGCGGCGGCGGC
GACACCCCCATCACCCCAGCGTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCTCTGGACGTGCCTTCTCCTGTGCGCCGCA
CTCCGGACCCTCCTGGCCAGCCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCATGGGGGACCTGGGATGGATTGCTTTTCCA
AAAAATGGGTGGGAAGAGATTGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCAAGTATGCAAAGTGATGGAACAGAATCAG
AATAACTGGCTTTTGACCAGTTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACTCAAATTTACCCTGCGGGACTGCAACAGC
CTTCCTGGAGGACTGGGGACCTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGATCAGAATGGGAGAAACATCAAGGAAAAC
CAATACATCAAAATTGATACCATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGACCGTGTTATGAAACTGAATACAGAGGTC
AGAGATGTAGGACCTCTAAGCAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTGCATTGCTCTGGTTTCTGTGCGTGTATAC
TATAAAAAATGCCCTTCTGTGGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGCTGATTCTTCCCAATTGCTCGAAGTGTCA
GGCTCCTGTGTCAACCATTCTGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGGGGAGTGGCTGGTGCCCATCGGGAAATGC
ATGTGCAAGGCAGGATATGAAGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTTCAAAGCCTCACCTCACATCCAGAGCTGC
GGCAAATGTCCACCTCACAGTTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAAGGATTATTTCAGGAGAGAGTCTGATCCA
CCCACAATGGCATGCACAAGACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGAAACTAGTGTCTTTCTGGAATGGATTCCG
CCTGCTGACACTGGTGGAAGGAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTCCCATGCAGGTGTGTGTGAGGAGTGTGGC
GGTCATGTCAGGTACCTTCCCCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGATCTACTCGCTCACACAAACTATACCTTT
GAGATTGAGGCAGTGAATGGAGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGTAAATGTAACCACAAATCAAGCAGATCCT
AATTATCTCATGGCTAATGAACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGGCTTGATTGAATCAGCTCTGAACCTGGGG
AGGACTCTTGACTCTGACTATGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCTGAAACATGGCTTGAAAGCTAAAAAAACT
TTTCTCGGACAAAATAAATCCTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGAAGCCGCAGAGATAACAGCAAGTGTTAAA
GATCTTCCAGGACTTAAGACACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAATGCAAAAGAAACTTTCAGAATATATGAAA
GCTTTGATCAATAAGAAAGAACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGAAGAAGAAGGAGCCATAATTGCTGGTCTG
TTGGTGGGTCTGAATGTCATTGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCAGGTTGGAGTTATAGATTTTTCAATGTAT
CTCAAGGACGGGAACAGCAGTAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGACCAGAAGAACTATGTAGAAGAACTGAAC
AGACATTTGAATGCTACTGTAAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAACACTAAACTGACAGAGGAGCTTGCAGTT
GCAAACAACAGGATCATTACCTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTACATACTGGAATCCAATCGGAAGGGTCCC
AAGCAAGACAGAACTGCAGAAGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGAGACACAATTACGATTGGATGTTGAGAAA
GAACTGGAGATGCAGATCAGCATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAAGGATGTCTGTGAGAAGCAGGATGCCCTG
GTATCTCTTCGGCAGCAGCTGGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCTGCAGAGTTCAGACTTAGGAGTAAAACAG
AAAAGTGAACTAAACAGTCGCTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACAACTTGAACAAAGGTAAAAGTCCTGTTTC
TTTAATGAAACACTTTGGATTGTCAGTGCTGAAGTGAAAAGAATGTGCTGTACATTCGGCAAATAGAAAATACATGAAATTCTTCCAAAT
TAGCATCAGACATTCTGGTAGAAAAAAGCCAGTTGAATGTTATGTGTGTTTTCTAAGGTATGACTGAAATGTTTTTAGGAAATGTCAATC
ACTTGACTAGCCTTTAAAAAAAAAAAAGAAAGGTCAGCCTTTTATGACTGTTTTGAACATCAGAACTCTTAATCCATGTCAGAGTCATGT
GTTAGAGGAAGGATACTTAAAAGCATGGAAGGACTCTTAAATGTATGTATGTAATTCTGTGATTTTATTGTTCATCACTGAAGTCTTTGA
ATACTTGGATGCTAGGGGATATAGAGGCACTGAGAGATAGGTGTCCTCCAAGGATCTATTCTGGATCTTTCTCTCCCTTCTTTAACCCTT

>In-frame_ENST00000511294_ENST00000417478_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=854AA_start in transcript=753_stop in transcript=3317
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR

--------------------------------------------------------------
>In-frame_ENST00000511294_ENST00000381006_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=4496nt_BP=2155nt
CCAGACACAGCAGGAGCGCGCCTTGGCGGTGCAGTTTCAACCTCGACTTCGCAGCCGCGCACACACCGCCTGCTCCCCGAGCAGCGGGAA
CCGCAGCAGCTCCTGGGCCGCCGCAGCGCAGCTCCGCGCTCCTACCGGCCGGCAGCCGTCAGTCCCTCCCCTCTTCAGCACTCAGCCCGC
AGCTATTTCCTTCTGCCAGTCTCTTTGAACTCTGGATCTTTGCTTTTGCTCGCTGCTCTCCTGTTTTTCATTCTCCACATTTTCTCAAGT
CCTCTTTCTTTATCCTTAGCCACCCTGCTTTTTTCCTCCTTTTTTAAAAAATCGGAGATTTCGTCTTAAAATGATTTGCCTTCCTTACCT
TCGTCCATTTCAACACTGAAGGCTGCAAAGAACCTTCACCTTTCCCCTAGTGGTATTTAAAAATTCTCAATCCGTAAAAAGTCTTTTTGA
AAGGCAAAGGAACAGGACCCAGGACCCTCTCGACACCCTTGATCCGAGTCCAGATCTGCACTAGCAACCAGAACTAATATTTCATTTAAC
CCCACCAAAGGGGGAGGCGAGAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGTGGTTCCTACATTTGGAGGAGCCGCGTGC
CAGAAGGCGTAGGACCCCAAGGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTGCGAGGCCGAAGCGGTGGACTGAGCCGCT
CGGGACAGCGGCACCGGAGGAGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGGACGCCGGCGGCCCCCAAGCGGCGGCGGC
GACACCCCCATCACCCCAGCGTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCTCTGGACGTGCCTTCTCCTGTGCGCCGCA
CTCCGGACCCTCCTGGCCAGCCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCATGGGGGACCTGGGATGGATTGCTTTTCCA
AAAAATGGGTGGGAAGAGATTGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCAAGTATGCAAAGTGATGGAACAGAATCAG
AATAACTGGCTTTTGACCAGTTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACTCAAATTTACCCTGCGGGACTGCAACAGC
CTTCCTGGAGGACTGGGGACCTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGATCAGAATGGGAGAAACATCAAGGAAAAC
CAATACATCAAAATTGATACCATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGACCGTGTTATGAAACTGAATACAGAGGTC
AGAGATGTAGGACCTCTAAGCAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTGCATTGCTCTGGTTTCTGTGCGTGTATAC
TATAAAAAATGCCCTTCTGTGGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGCTGATTCTTCCCAATTGCTCGAAGTGTCA
GGCTCCTGTGTCAACCATTCTGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGGGGAGTGGCTGGTGCCCATCGGGAAATGC
ATGTGCAAGGCAGGATATGAAGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTTCAAAGCCTCACCTCACATCCAGAGCTGC
GGCAAATGTCCACCTCACAGTTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAAGGATTATTTCAGGAGAGAGTCTGATCCA
CCCACAATGGCATGCACAAGACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGAAACTAGTGTCTTTCTGGAATGGATTCCG
CCTGCTGACACTGGTGGAAGGAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTCCCATGCAGGTGTGTGTGAGGAGTGTGGC
GGTCATGTCAGGTACCTTCCCCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGATCTACTCGCTCACACAAACTATACCTTT
GAGATTGAGGCAGTGAATGGAGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGTAAATGTAACCACAAATCAAGCAGATCCT
AATTATCTCATGGCTAATGAACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGGCTTGATTGAATCAGCTCTGAACCTGGGG
AGGACTCTTGACTCTGACTATGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCTGAAACATGGCTTGAAAGCTAAAAAAACT
TTTCTCGGACAAAATAAATCCTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGAAGCCGCAGAGATAACAGCAAGTGTTAAA
GATCTTCCAGGACTTAAGACACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAATGCAAAAGAAACTTTCAGAATATATGAAA
GCTTTGATCAATAAGAAAGAACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGAAGAAGAAGGAGCCATAATTGCTGGTCTG
TTGGTGGGTCTGAATGTCATTGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCAGGTTGGAGTTATAGATTTTTCAATGTAT
CTCAAGGACGGGAACAGCAGTAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGACCAGAAGAACTATGTAGAAGAACTGAAC
AGACATTTGAATGCTACTGTAAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAACACTAAACTGACAGAGGAGCTTGCAGTT
GCAAACAACAGGATCATTACCTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTACATACTGGAATCCAATCGGAAGGGTCCC
AAGCAAGACAGAACTGCAGAAGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGAGACACAATTACGATTGGATGTTGAGAAA
GAACTGGAGATGCAGATCAGCATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAAGGATGTCTGTGAGAAGCAGGATGCCCTG
GTATCTCTTCGGCAGCAGCTGGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCTGCAGAGTTCAGACTTAGGAGTAAAACAG
AAAAGTGAACTAAACAGTCGCTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACAACTTGAACAAAGATTGCGCCAGGCTGAG
CGAAGCCGCCAATCTGCTGAGTTGGACAACCGGCTCTTCAAACAGGACTTTGGAGACAAGATCAACAGTCTGCAGCTGGAAGTCGAGGAG
CTCACCAGGCAGCGGAACCAGCTTGAGTTAGAACTAAAACAGGAAAAAGAAAGAAGATTACAAAACGACAGGAGCATCCCAGGAAGGGGT
TCCCAGAAGTCAGAATCCAAGATGGATGGGAAGCACAAAATGCAAGAGGAAAATGTTAAACTAAAAAAGCCCCTGGAAGAAAGCCACAGG
CTGCAACCCCACCCTATGGATGAACAGGATCAGCTGCTGCTCTCTGAAAAGCCACAGTTGTGTCAGCTATGCCAGGAAGACGGCAGCCTA
ACAAAGAATGTGTGTAAGAACTGCAGCGGAACCTTCTGTGATGCCTGTTCAACAAATGAACTGCCTCTTCCTTCAAGTATCAAGCTTGAG
CGAGTTTGCAATCCCTGTCACAAGCATCTGATGAAGCAATATTCTACCAGCCCATCATAAGACTGGAGGCCAAGACCTGGACCAAAACGT
TTATGCAGGCTCCTCTGTACCTGTGTTTTAGCTGTCAGGATCTCATAGAGCCCAGTTCTTAGAGTCAACTAAAGAGTTGATAGGAATTTA
CTAGGTCCAGGGAGAAAAGGCAGTGGTTGGGGTTACTGGAAATTTTGCTCATTTTCTCTAATGACTGTATGAATAAAAGTGAACTTACTT
GAGCCTTTCTCTTCTAAATCTAAACAACCTGATATTGAAGGTTTGCTTTATAGCATATCTTTGGAAAGGCAACTCATTTTTATGATTAGT
GATACTGGGGTGGATTTAATAGGAGAGAGAATCCAGGCAGATAAGAATAAAAAGGAAAATGATCATCTCCTTCTATAGCATTTGCAGATT
CAAGGGGGAGAGGTAGATGCTGAGATCAAAATGACAGTTGTTACTTATTTTTCCAGGTGCTGTTAGTATAAACATTGTTTCCTCTTCACC
CCTGCTAACTACCTCTTTAAAGTATTTCTACCAAACTGTGAACCCAATCTCAGGGAAAAGAAATTAAAAAGTAATATAAATTCTGCATAT

>In-frame_ENST00000511294_ENST00000381006_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=1028AA_start in transcript=753_stop in transcript=3839
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR
ALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNRLFKQDFGDKINSLQLEVEELTRQRNQLELE
LKQEKERRLQNDRSIPGRGSQKSESKMDGKHKMQEENVKLKKPLEESHRLQPHPMDEQDQLLLSEKPQLCQLCQEDGSLTKNVCKNCSGT

--------------------------------------------------------------
>In-frame_ENST00000511294_ENST00000226328_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=5647nt_BP=2155nt
CCAGACACAGCAGGAGCGCGCCTTGGCGGTGCAGTTTCAACCTCGACTTCGCAGCCGCGCACACACCGCCTGCTCCCCGAGCAGCGGGAA
CCGCAGCAGCTCCTGGGCCGCCGCAGCGCAGCTCCGCGCTCCTACCGGCCGGCAGCCGTCAGTCCCTCCCCTCTTCAGCACTCAGCCCGC
AGCTATTTCCTTCTGCCAGTCTCTTTGAACTCTGGATCTTTGCTTTTGCTCGCTGCTCTCCTGTTTTTCATTCTCCACATTTTCTCAAGT
CCTCTTTCTTTATCCTTAGCCACCCTGCTTTTTTCCTCCTTTTTTAAAAAATCGGAGATTTCGTCTTAAAATGATTTGCCTTCCTTACCT
TCGTCCATTTCAACACTGAAGGCTGCAAAGAACCTTCACCTTTCCCCTAGTGGTATTTAAAAATTCTCAATCCGTAAAAAGTCTTTTTGA
AAGGCAAAGGAACAGGACCCAGGACCCTCTCGACACCCTTGATCCGAGTCCAGATCTGCACTAGCAACCAGAACTAATATTTCATTTAAC
CCCACCAAAGGGGGAGGCGAGAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGTGGTTCCTACATTTGGAGGAGCCGCGTGC
CAGAAGGCGTAGGACCCCAAGGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTGCGAGGCCGAAGCGGTGGACTGAGCCGCT
CGGGACAGCGGCACCGGAGGAGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGGACGCCGGCGGCCCCCAAGCGGCGGCGGC
GACACCCCCATCACCCCAGCGTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCTCTGGACGTGCCTTCTCCTGTGCGCCGCA
CTCCGGACCCTCCTGGCCAGCCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCATGGGGGACCTGGGATGGATTGCTTTTCCA
AAAAATGGGTGGGAAGAGATTGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCAAGTATGCAAAGTGATGGAACAGAATCAG
AATAACTGGCTTTTGACCAGTTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACTCAAATTTACCCTGCGGGACTGCAACAGC
CTTCCTGGAGGACTGGGGACCTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGATCAGAATGGGAGAAACATCAAGGAAAAC
CAATACATCAAAATTGATACCATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGACCGTGTTATGAAACTGAATACAGAGGTC
AGAGATGTAGGACCTCTAAGCAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTGCATTGCTCTGGTTTCTGTGCGTGTATAC
TATAAAAAATGCCCTTCTGTGGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGCTGATTCTTCCCAATTGCTCGAAGTGTCA
GGCTCCTGTGTCAACCATTCTGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGGGGAGTGGCTGGTGCCCATCGGGAAATGC
ATGTGCAAGGCAGGATATGAAGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTTCAAAGCCTCACCTCACATCCAGAGCTGC
GGCAAATGTCCACCTCACAGTTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAAGGATTATTTCAGGAGAGAGTCTGATCCA
CCCACAATGGCATGCACAAGACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGAAACTAGTGTCTTTCTGGAATGGATTCCG
CCTGCTGACACTGGTGGAAGGAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTCCCATGCAGGTGTGTGTGAGGAGTGTGGC
GGTCATGTCAGGTACCTTCCCCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGATCTACTCGCTCACACAAACTATACCTTT
GAGATTGAGGCAGTGAATGGAGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGTAAATGTAACCACAAATCAAGCAGATCCT
AATTATCTCATGGCTAATGAACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGGCTTGATTGAATCAGCTCTGAACCTGGGG
AGGACTCTTGACTCTGACTATGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCTGAAACATGGCTTGAAAGCTAAAAAAACT
TTTCTCGGACAAAATAAATCCTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGAAGCCGCAGAGATAACAGCAAGTGTTAAA
GATCTTCCAGGACTTAAGACACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAATGCAAAAGAAACTTTCAGAATATATGAAA
GCTTTGATCAATAAGAAAGAACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGAAGAAGAAGGAGCCATAATTGCTGGTCTG
TTGGTGGGTCTGAATGTCATTGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCAGGTTGGAGTTATAGATTTTTCAATGTAT
CTCAAGGACGGGAACAGCAGTAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGACCAGAAGAACTATGTAGAAGAACTGAAC
AGACATTTGAATGCTACTGTAAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAACACTAAACTGACAGAGGAGCTTGCAGTT
GCAAACAACAGGATCATTACCTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTACATACTGGAATCCAATCGGAAGGGTCCC
AAGCAAGACAGAACTGCAGAAGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGAGACACAATTACGATTGGATGTTGAGAAA
GAACTGGAGATGCAGATCAGCATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAAGGATGTCTGTGAGAAGCAGGATGCCCTG
GTATCTCTTCGGCAGCAGCTGGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCTGCAGAGTTCAGACTTAGGAGTAAAACAG
AAAAGTGAACTAAACAGTCGCTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACAACTTGAACAAAGTGAAAAGGATTTGGTG
AAACAGGCAAAGACCTTAAATAGTGCAGCAAATAAACTGATCCCAAAACATCATTAGGCATTTTTAAGTTGGTCACGTCGCAAGTCCGAT
ATCACAACTTAATTGTAAAAGGAAGAAATCTGAAAGTTACTACATTTAAGCTCTGATTCTATATAAAATGTCACCAAAAAGTTGACTTTG
AATTTGTTGGACTTTTAAAAAACCAGTTGGAAATATAGGTTGGGTTTTTTTCTTATTGTTTTCTCCCCAGGGTTAGAAAAATTGGTATAA
GTTCCTAATTAAAAGCTGAATAAACTTTGAGAAATTATTTCTGAGTTGACCAATAAATAAAAATACCACTTTCTTTAAAAAAGCCTAGGG
AATTGAAGCTCTGTACATATACTAATGATGCCTTTACAACCCAGTCCTTGATAATACCAGATTCTCGGTGCATTGTTCATGTCTGTATCT
GCAAGCCTGTTCTGCCATTGCAGTGTGATGAACCTAGAGGTAACTACCATGTGAACTTGAACTCTTCTAAAATAGTTCTGTGTCTCTTAG
ACCATGACCCCTTTTCACTTTTGTTATATAGGTTTAATCCCCAAGCCAAGGATAGTACTTAGTATTTCACTACACTTCTATTCTCAGTAA
CCAAGATTGCTTGCAACTTTTTTTGCCTTGGTGACTTTTGAAAAAAAAAGAAAAGAAAAAGCAGCATCCTTATATTTCTTTAAAATACAT
AGAAATAAAGTTAGTAATTAGGTAACCTATGATAACATAATAATGTGGACGCCTGGGGAAACCCTCCTCATGTTTGTCATCTTCTACCTC
TGCCGTTTTCCTGCAATTCCGCTTCCTACTTAGGCAGTTCAGAGAGAACAATTCTAATAAAAACACTCCTCTCCTATTAACAAAAAATGA
TGCAGTACCCATTTTTCGTATCCTGCTTTTCTTATATTGGAGTAAAAAGGACAGGGTATAGACATGAATGATGATATTCTGCCTGGCCTG
TCATTTCTTACCTGGAAACATTTACTTAAGAGTTTCTGTTACTTTTTGTTCAGATGGGGATTTGCTAAAGGTTCTGGGAAGCTAATAATT
GAATTATTAGAAAAACATTTCAGAATAGGAAGTAAATGATAAACTTATATTCTTTATTATTATTTAGTACAAAAATAGATTCCCAGTAGA
TATCCACAAGCAATATTAGCAGGGCTTCTGTTTCTAAGTGACCACAGACTAACCCTTTCTAGGCTTTAACATTGTAAATAATCCTATAAA
CAGTTTGATTTTTTAAGATGATTTTTGATTTGAAGAGACAGGCTTTACATAAGCCTTCATTCCTTCAAAAGGTCCTGACAAAATACTTGG
GTTTTTTTCTCTTTTTTTCATTCTGGTATGCTTTGCAGCATTTCAGCTGCTTTGGTGGGGACACAGATAACCCCTTCGCTTCCAGCTCTT
AAAATTCTTTATCTTTTTCTTGGCAAAACCAGAATTAAGAGTGTAAGATAGATTCCATGTGTGCTTATATAGGTCCCTGCACAGATTGGA
CTTGAACCAAAATTAAGTCCAAAGAACATATGTTTAGACCAACTTCATGGAAGTGGAAGATCCTGTGCTCTTGAACTTATTTTAATTCTT
ATAATTTGCACCTATATAAACAAAGCTCCTACTGTATTCTTCTCTTCATCAACCTTTTGTGGTGATGGGTTGCCTTTTCTACGAGCATTT
GGAAGGAGTGATCAAATACCGAAATTGAACTTTCTAAAACCTACACATAGCATGCGTTTAAATTCTATTATATAAAGCCCCAAGTGCTTT
ACCTTCTAAAACATGCTTCTCTATAGGTGCAAAGTTATAAGATATGTAGAAGAAAACATCCATCAGAATCTTCTGGAGAATATGGTCAGA
GTCTTAAACAGGCCCAGTGCTGAGTTCTTTGTCCACTTAGTCACACATCTTTTGTGGGAATGGGAAAGGAAGGAGACAGCCAAACTCTGA
CAAAGGCTTTTCCTTATAGAATAACCCAAAGCCTAGGTGAGGGTTGATATATAATGTCCCATGATTTAATATATGTGGTTTGGGGGAAAG
GACAAGAAAAAACTATAATTCCACATATAAGAAGGTAGTTGCCCATTTACAAGTTCCAGTTATGTGTGTAAAACAGAAAAATTAAGTACC
AAACCTATTAGGAAATTTTTTTAAAAAGTGGATTTAACTTAAATTACTGTGTACTTGAGGTTGGCTTTGGATATGGATTTTCTAAAAAGT

>In-frame_ENST00000511294_ENST00000226328_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=877AA_start in transcript=753_stop in transcript=3386
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR

--------------------------------------------------------------
>In-frame_ENST00000511294_ENST00000536664_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=3425nt_BP=2155nt
CCAGACACAGCAGGAGCGCGCCTTGGCGGTGCAGTTTCAACCTCGACTTCGCAGCCGCGCACACACCGCCTGCTCCCCGAGCAGCGGGAA
CCGCAGCAGCTCCTGGGCCGCCGCAGCGCAGCTCCGCGCTCCTACCGGCCGGCAGCCGTCAGTCCCTCCCCTCTTCAGCACTCAGCCCGC
AGCTATTTCCTTCTGCCAGTCTCTTTGAACTCTGGATCTTTGCTTTTGCTCGCTGCTCTCCTGTTTTTCATTCTCCACATTTTCTCAAGT
CCTCTTTCTTTATCCTTAGCCACCCTGCTTTTTTCCTCCTTTTTTAAAAAATCGGAGATTTCGTCTTAAAATGATTTGCCTTCCTTACCT
TCGTCCATTTCAACACTGAAGGCTGCAAAGAACCTTCACCTTTCCCCTAGTGGTATTTAAAAATTCTCAATCCGTAAAAAGTCTTTTTGA
AAGGCAAAGGAACAGGACCCAGGACCCTCTCGACACCCTTGATCCGAGTCCAGATCTGCACTAGCAACCAGAACTAATATTTCATTTAAC
CCCACCAAAGGGGGAGGCGAGAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGTGGTTCCTACATTTGGAGGAGCCGCGTGC
CAGAAGGCGTAGGACCCCAAGGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTGCGAGGCCGAAGCGGTGGACTGAGCCGCT
CGGGACAGCGGCACCGGAGGAGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGGACGCCGGCGGCCCCCAAGCGGCGGCGGC
GACACCCCCATCACCCCAGCGTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCTCTGGACGTGCCTTCTCCTGTGCGCCGCA
CTCCGGACCCTCCTGGCCAGCCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCATGGGGGACCTGGGATGGATTGCTTTTCCA
AAAAATGGGTGGGAAGAGATTGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCAAGTATGCAAAGTGATGGAACAGAATCAG
AATAACTGGCTTTTGACCAGTTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACTCAAATTTACCCTGCGGGACTGCAACAGC
CTTCCTGGAGGACTGGGGACCTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGATCAGAATGGGAGAAACATCAAGGAAAAC
CAATACATCAAAATTGATACCATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGACCGTGTTATGAAACTGAATACAGAGGTC
AGAGATGTAGGACCTCTAAGCAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTGCATTGCTCTGGTTTCTGTGCGTGTATAC
TATAAAAAATGCCCTTCTGTGGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGCTGATTCTTCCCAATTGCTCGAAGTGTCA
GGCTCCTGTGTCAACCATTCTGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGGGGAGTGGCTGGTGCCCATCGGGAAATGC
ATGTGCAAGGCAGGATATGAAGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTTCAAAGCCTCACCTCACATCCAGAGCTGC
GGCAAATGTCCACCTCACAGTTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAAGGATTATTTCAGGAGAGAGTCTGATCCA
CCCACAATGGCATGCACAAGACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGAAACTAGTGTCTTTCTGGAATGGATTCCG
CCTGCTGACACTGGTGGAAGGAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTCCCATGCAGGTGTGTGTGAGGAGTGTGGC
GGTCATGTCAGGTACCTTCCCCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGATCTACTCGCTCACACAAACTATACCTTT
GAGATTGAGGCAGTGAATGGAGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGTAAATGTAACCACAAATCAAGCAGATCCT
AATTATCTCATGGCTAATGAACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGGCTTGATTGAATCAGCTCTGAACCTGGGG
AGGACTCTTGACTCTGACTATGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCTGAAACATGGCTTGAAAGCTAAAAAAACT
TTTCTCGGACAAAATAAATCCTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGAAGCCGCAGAGATAACAGCAAGTGTTAAA
GATCTTCCAGGACTTAAGACACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAATGCAAAAGAAACTTTCAGAATATATGAAA
GCTTTGATCAATAAGAAAGAACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGAAGAAGAAGGAGCCATAATTGCTGGTCTG
TTGGTGGGTCTGAATGTCATTGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCAGGTTGGAGTTATAGATTTTTCAATGTAT
CTCAAGGACGGGAACAGCAGTAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGACCAGAAGAACTATGTAGAAGAACTGAAC
AGACATTTGAATGCTACTGTAAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAACACTAAACTGACAGAGGAGCTTGCAGTT
GCAAACAACAGGATCATTACCTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTACATACTGGAATCCAATCGGAAGGGTCCC
AAGCAAGACAGAACTGCAGAAGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGAGACACAATTACGATTGGATGTTGAGAAA
GAACTGGAGATGCAGATCAGCATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAAGGATGTCTGTGAGAAGCAGGATGCCCTG
GTATCTCTTCGGCAGCAGCTGGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCTGCAGAGTTCAGACTTAGGAGTAAAACAG
AAAAGTGAACTAAACAGTCGCTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACAACTTGAACAAAGTGAAAAGGATTTGGTG
AAACAGGCAAAGACCTTAAATAGTGCAGCAAATAAACTGATCCCAAAACATCATTAGGCATTTTTAAGTTGGTCACGTCGCAAGTCCGAT

>In-frame_ENST00000511294_ENST00000536664_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=877AA_start in transcript=753_stop in transcript=3386
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR

--------------------------------------------------------------
>In-frame_ENST00000511294_ENST00000502653_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(transcript)=4283nt_BP=2155nt
CCAGACACAGCAGGAGCGCGCCTTGGCGGTGCAGTTTCAACCTCGACTTCGCAGCCGCGCACACACCGCCTGCTCCCCGAGCAGCGGGAA
CCGCAGCAGCTCCTGGGCCGCCGCAGCGCAGCTCCGCGCTCCTACCGGCCGGCAGCCGTCAGTCCCTCCCCTCTTCAGCACTCAGCCCGC
AGCTATTTCCTTCTGCCAGTCTCTTTGAACTCTGGATCTTTGCTTTTGCTCGCTGCTCTCCTGTTTTTCATTCTCCACATTTTCTCAAGT
CCTCTTTCTTTATCCTTAGCCACCCTGCTTTTTTCCTCCTTTTTTAAAAAATCGGAGATTTCGTCTTAAAATGATTTGCCTTCCTTACCT
TCGTCCATTTCAACACTGAAGGCTGCAAAGAACCTTCACCTTTCCCCTAGTGGTATTTAAAAATTCTCAATCCGTAAAAAGTCTTTTTGA
AAGGCAAAGGAACAGGACCCAGGACCCTCTCGACACCCTTGATCCGAGTCCAGATCTGCACTAGCAACCAGAACTAATATTTCATTTAAC
CCCACCAAAGGGGGAGGCGAGAGGAGCCAGAAGCAAACTTCAGCTGTCTCAGCCGGATCCGTGGTTCCTACATTTGGAGGAGCCGCGTGC
CAGAAGGCGTAGGACCCCAAGGGGGGACAAGGAGGACTCCCGAGTCTCCCTTCGCCGCTCTGCGAGGCCGAAGCGGTGGACTGAGCCGCT
CGGGACAGCGGCACCGGAGGAGGCTCGGAGAAGATGCGGGGCTCGGGGCCCCGGGGTGCGGGACGCCGGCGGCCCCCAAGCGGCGGCGGC
GACACCCCCATCACCCCAGCGTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCTCTGGACGTGCCTTCTCCTGTGCGCCGCA
CTCCGGACCCTCCTGGCCAGCCCCAGCAACGAAGTGAATTTATTGGATTCACGCACTGTCATGGGGGACCTGGGATGGATTGCTTTTCCA
AAAAATGGGTGGGAAGAGATTGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCAAGTATGCAAAGTGATGGAACAGAATCAG
AATAACTGGCTTTTGACCAGTTGGATCTCCAATGAAGGTGCTTCCAGAATCTTCATAGAACTCAAATTTACCCTGCGGGACTGCAACAGC
CTTCCTGGAGGACTGGGGACCTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGATCAGAATGGGAGAAACATCAAGGAAAAC
CAATACATCAAAATTGATACCATTGCTGCCGATGAAAGCTTTACAGAACTTGATCTTGGTGACCGTGTTATGAAACTGAATACAGAGGTC
AGAGATGTAGGACCTCTAAGCAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTGCATTGCTCTGGTTTCTGTGCGTGTATAC
TATAAAAAATGCCCTTCTGTGGTACGACACTTGGCTGTCTTCCCTGACACCATCACTGGAGCTGATTCTTCCCAATTGCTCGAAGTGTCA
GGCTCCTGTGTCAACCATTCTGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGGGGAGTGGCTGGTGCCCATCGGGAAATGC
ATGTGCAAGGCAGGATATGAAGAGAAAAATGGCACCTGTCAAGTGTGCAGACCTGGGTTCTTCAAAGCCTCACCTCACATCCAGAGCTGC
GGCAAATGTCCACCTCACAGTTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAAGGATTATTTCAGGAGAGAGTCTGATCCA
CCCACAATGGCATGCACAAGACCCCCCTCTGCTCCTCGGAATGCCATCTCAAATGTTAATGAAACTAGTGTCTTTCTGGAATGGATTCCG
CCTGCTGACACTGGTGGAAGGAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTCCCATGCAGGTGTGTGTGAGGAGTGTGGC
GGTCATGTCAGGTACCTTCCCCGGCAAAGCGGCCTGAAAAACACCTCTGTCATGATGGTGGATCTACTCGCTCACACAAACTATACCTTT
GAGATTGAGGCAGTGAATGGAGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGTAAATGTAACCACAAATCAAGCAGATCCT
AATTATCTCATGGCTAATGAACGCATGAACCTCATGAACATGGCCAAGCTGAGTATCAAGGGCTTGATTGAATCAGCTCTGAACCTGGGG
AGGACTCTTGACTCTGACTATGCACCTCTCCAGCAATTCTTTGTGGTGATGGAGCACTGTCTGAAACATGGCTTGAAAGCTAAAAAAACT
TTTCTCGGACAAAATAAATCCTTCTGGGGGCCTCTAGAACTGGTAGAAAAGCTTGTTCCAGAAGCCGCAGAGATAACAGCAAGTGTTAAA
GATCTTCCAGGACTTAAGACACCAGTAGGTAGAGGAAGAGCCTGGCTTCGTTTGGCATTAATGCAAAAGAAACTTTCAGAATATATGAAA
GCTTTGATCAATAAGAAAGAACTTCTCAGTGAATTCTACGAACCCAATGCCCTCATGATGGAAGAAGAAGGAGCCATAATTGCTGGTCTG
TTGGTGGGTCTGAATGTCATTGATGCCAATTTCTGTATGAAAGGAGAAGACTTGGACTCTCAGGTTGGAGTTATAGATTTTTCAATGTAT
CTCAAGGACGGGAACAGCAGTAAAGGTACTGAAGGAGACGGTCAGATTACTGCAATTCTGGACCAGAAGAACTATGTAGAAGAACTGAAC
AGACATTTGAATGCTACTGTAAACAACCTTCAGGCAAAAGTAGATGCATTAGAAAAATCCAACACTAAACTGACAGAGGAGCTTGCAGTT
GCAAACAACAGGATCATTACCTTACAAGAAGAAATGGAACGAGTTAAAGAGGAAAGTTCCTACATACTGGAATCCAATCGGAAGGGTCCC
AAGCAAGACAGAACTGCAGAAGGGCAAGCACTAAGTGAAGCAAGAAAGCATTTAAAAGAAGAGACACAATTACGATTGGATGTTGAGAAA
GAACTGGAGATGCAGATCAGCATGAGGCAGGAGATGGAATTGGCTATGAAGATGCTGGAGAAGGATGTCTGTGAGAAGCAGGATGCCCTG
GTATCTCTTCGGCAGCAGCTGGATGACCTCAGAGCTCTCAAGCATGAACTTGCCTTTAAGCTGCAGAGTTCAGACTTAGGAGTAAAACAG
AAAAGTGAACTAAACAGTCGCTTGGAAGAGAAGACTAATCAGATGGCTGCTACCATTAAACAACTTGAACAAAGATTGCGCCAGGCTGAG
CGAAGCCGCCAATCTGCTGAGTTGGACAACCGGCTCTTCAAACAGGACTTTGGAGACAAGATCAACAGTCTGCAGCTGGAAGTCGAGGAG
CTCACCAGGCAGCGGAACCAGCTTGAGTTAGAACTAAAACAGGAAAAAGAAAGAAGATTACAAAACGACAGGAGCATCCCAGGAAGGGGT
TCCCAGAAGTCAGAATCCAAGATGGATGGGAAGCACAAAATGCAAGAGGAAAATGTTAAACTAAAAAAGCCCCTGGAAGAAAGCCACAGG
CTGCAACCCCACCCTATGGATGAACAGGATCAGCTGCTGCTCTCTGAAAAGCCACAGTTGTGTCAGCTATGCCAGGAAGACGGCAGCCTA
ACAAAGAATGTGTGTAAGAACTGCAGCGGAACCTTCTGTGATGCCTGTTCAACAAATGAACTGCCTCTTCCTTCAAGTATCAAGCTTGAG
CGAGTTTGCAATCCCTGTCACAAGCATCTGATGAAGCAATATTCTACCAGCCCATCATAAGACTGGAGGCCAAGACCTGGACCAAAACGT
TTATGCAGGCTCCTCTGTACCTGTGTTTTAGCTGTCAGGATCTCATAGAGCCCAGTTCTTAGAGTCAACTAAAGAGTTGATAGGAATTTA
CTAGGTCCAGGGAGAAAAGGCAGTGGTTGGGGTTACTGGAAATTTTGCTCATTTTCTCTAATGACTGTATGAATAAAAGTGAACTTACTT
GAGCCTTTCTCTTCTAAATCTAAACAACCTGATATTGAAGGTTTGCTTTATAGCATATCTTTGGAAAGGCAACTCATTTTTATGATTAGT
GATACTGGGGTGGATTTAATAGGAGAGAGAATCCAGGCAGATAAGAATAAAAAGGAAAATGATCATCTCCTTCTATAGCATTTGCAGATT

>In-frame_ENST00000511294_ENST00000502653_TCGA-91-6848-01A_EPHA5_chr4_66356095_-_RUFY3_chr4_71628236_length(amino acids)=1028AA_start in transcript=753_stop in transcript=3839
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVD
ENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE
PPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
SPGARQYVSVNVTTNQADPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGP
LELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEE
MERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR
ALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNRLFKQDFGDKINSLQLEVEELTRQRNQLELE
LKQEKERRLQNDRSIPGRGSQKSESKMDGKHKMQEENVKLKKPLEESHRLQPHPMDEQDQLLLSEKPQLCQLCQEDGSLTKNVCKNCSGT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for EPHA5-RUFY3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EPHA5-RUFY3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneEPHA5P54756DB01254DasatinibSmall moleculeApproved|Investigational
HgeneEPHA5P54756DB01254DasatinibSmall moleculeApproved|Investigational
HgeneEPHA5P54756DB01254DasatinibSmall moleculeApproved|Investigational
HgeneEPHA5P54756DB01254DasatinibSmall moleculeApproved|Investigational
HgeneEPHA5P54756DB01254DasatinibSmall moleculeApproved|Investigational
HgeneEPHA5P54756DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneEPHA5P54756DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneEPHA5P54756DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneEPHA5P54756DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneEPHA5P54756DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational

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Related Diseases for EPHA5-RUFY3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneRUFY3C0037274Dermatologic disorders1CTD_human
TgeneRUFY3C0274861Arsenic Poisoning, Inorganic1CTD_human
TgeneRUFY3C0274862Nervous System, Organic Arsenic Poisoning1CTD_human
TgeneRUFY3C0311375Arsenic Poisoning1CTD_human
TgeneRUFY3C0751851Arsenic Encephalopathy1CTD_human
TgeneRUFY3C0751852Arsenic Induced Polyneuropathy1CTD_human