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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ERBB2-CNIH4 (FusionGDB2 ID:27109)

Fusion Gene Summary for ERBB2-CNIH4

check button Fusion gene summary
Fusion gene informationFusion gene name: ERBB2-CNIH4
Fusion gene ID: 27109
HgeneTgene
Gene symbol

ERBB2

CNIH4

Gene ID

2064

29097

Gene nameerb-b2 receptor tyrosine kinase 2cornichon family AMPA receptor auxiliary protein 4
SynonymsCD340|HER-2|HER-2/neu|HER2|MLN 19|NEU|NGL|TKR1CNIH-4|CNIH2|HSPC163
Cytomap

17q12

1q42.11

Type of geneprotein-codingprotein-coding
Descriptionreceptor tyrosine-protein kinase erbB-2c-erb B2/neu proteinherstatinhuman epidermal growth factor receptor 2metastatic lymph node gene 19 proteinneuro/glioblastoma derived oncogene homologneuroblastoma/glioblastoma derived oncogene homologp185erbB2protein cornichon homolog 4cornichon homolog 4
Modification date2020032920200313
UniProtAcc

P04626

Q9P003

Ensembl transtripts involved in fusion geneENST00000584601, ENST00000406381, 
ENST00000541774, ENST00000445658, 
ENST00000540147, ENST00000584450, 
ENST00000269571, ENST00000578199, 
ENST00000540042, ENST00000584888, 
ENST00000465271, ENST00000366858, 
ENST00000366857, ENST00000468318, 
ENST00000366856, 
Fusion gene scores* DoF score50 X 44 X 14=3080010 X 7 X 8=560
# samples 7313
** MAII scorelog2(73/30800*10)=-5.39889007670225
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/560*10)=-2.10691520391651
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ERBB2 [Title/Abstract] AND CNIH4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointERBB2(37866734)-CNIH4(224553581), # samples:2
Anticipated loss of major functional domain due to fusion event.ERBB2-CNIH4 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
ERBB2-CNIH4 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
ERBB2-CNIH4 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ERBB2-CNIH4 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneERBB2

GO:0007165

signal transduction

10572067

HgeneERBB2

GO:0007166

cell surface receptor signaling pathway

9685399

HgeneERBB2

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

7514177

HgeneERBB2

GO:0014065

phosphatidylinositol 3-kinase signaling

7556068

HgeneERBB2

GO:0018108

peptidyl-tyrosine phosphorylation

12000754

HgeneERBB2

GO:0032886

regulation of microtubule-based process

20937854

HgeneERBB2

GO:0035556

intracellular signal transduction

19372587

HgeneERBB2

GO:0042060

wound healing

12646923

HgeneERBB2

GO:0043406

positive regulation of MAP kinase activity

10572067

HgeneERBB2

GO:0045785

positive regulation of cell adhesion

7556068

HgeneERBB2

GO:0046777

protein autophosphorylation

7556068

HgeneERBB2

GO:0050679

positive regulation of epithelial cell proliferation

10572067

HgeneERBB2

GO:0071363

cellular response to growth factor stimulus

20010870

HgeneERBB2

GO:0090314

positive regulation of protein targeting to membrane

20010870


check buttonFusion gene breakpoints across ERBB2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across CNIH4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCECTCGA-D1-A3JP-01AERBB2chr17

37866734

+CNIH4chr1

224553581

+
ChimerDB4UCECTCGA-D1-A3JP-01AERBB2chr17

37866734

+CNIH4chr1

224553581

+
ChimerDB4UCECTCGA-D1-A3JP-01AERBB2chr17

37866134

+CNIH4chr1

224553581

+
ChimerDB4UCECTCGA-D1-A3JP-01AERBB2chr17

37863394

+CNIH4chr1

224553581

+


Top

Fusion Gene ORF analysis for ERBB2-CNIH4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000584601ENST00000465271ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000584601ENST00000366858ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000584601ENST00000366857ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584601ENST00000468318ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584601ENST00000366856ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000406381ENST00000465271ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000406381ENST00000366858ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000406381ENST00000366857ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000406381ENST00000468318ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000406381ENST00000366856ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000541774ENST00000465271ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000541774ENST00000366858ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000541774ENST00000366857ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000541774ENST00000468318ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000541774ENST00000366856ERBB2chr17

37866734

+CNIH4chr1

224553581

+
intron-3CDSENST00000445658ENST00000465271ERBB2chr17

37866734

+CNIH4chr1

224553581

+
intron-3CDSENST00000445658ENST00000366858ERBB2chr17

37866734

+CNIH4chr1

224553581

+
intron-3CDSENST00000445658ENST00000366857ERBB2chr17

37866734

+CNIH4chr1

224553581

+
intron-3UTRENST00000445658ENST00000468318ERBB2chr17

37866734

+CNIH4chr1

224553581

+
intron-3UTRENST00000445658ENST00000366856ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000540147ENST00000465271ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000540147ENST00000366858ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000540147ENST00000366857ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540147ENST00000468318ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540147ENST00000366856ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000584450ENST00000465271ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000584450ENST00000366858ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000584450ENST00000366857ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584450ENST00000468318ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584450ENST00000366856ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000269571ENST00000465271ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000269571ENST00000366858ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000269571ENST00000366857ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000269571ENST00000468318ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000269571ENST00000366856ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000578199ENST00000465271ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000578199ENST00000366858ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000578199ENST00000366857ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000578199ENST00000468318ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000578199ENST00000366856ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000540042ENST00000465271ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000540042ENST00000366858ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000540042ENST00000366857ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540042ENST00000468318ERBB2chr17

37866734

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540042ENST00000366856ERBB2chr17

37866734

+CNIH4chr1

224553581

+
intron-3CDSENST00000584888ENST00000465271ERBB2chr17

37866734

+CNIH4chr1

224553581

+
intron-3CDSENST00000584888ENST00000366858ERBB2chr17

37866734

+CNIH4chr1

224553581

+
intron-3CDSENST00000584888ENST00000366857ERBB2chr17

37866734

+CNIH4chr1

224553581

+
intron-3UTRENST00000584888ENST00000468318ERBB2chr17

37866734

+CNIH4chr1

224553581

+
intron-3UTRENST00000584888ENST00000366856ERBB2chr17

37866734

+CNIH4chr1

224553581

+
Frame-shiftENST00000584601ENST00000465271ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000584601ENST00000366858ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000584601ENST00000366857ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584601ENST00000468318ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584601ENST00000366856ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000406381ENST00000465271ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000406381ENST00000366858ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000406381ENST00000366857ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000406381ENST00000468318ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000406381ENST00000366856ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000541774ENST00000465271ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000541774ENST00000366858ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000541774ENST00000366857ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000541774ENST00000468318ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000541774ENST00000366856ERBB2chr17

37866134

+CNIH4chr1

224553581

+
intron-3CDSENST00000445658ENST00000465271ERBB2chr17

37866134

+CNIH4chr1

224553581

+
intron-3CDSENST00000445658ENST00000366858ERBB2chr17

37866134

+CNIH4chr1

224553581

+
intron-3CDSENST00000445658ENST00000366857ERBB2chr17

37866134

+CNIH4chr1

224553581

+
intron-3UTRENST00000445658ENST00000468318ERBB2chr17

37866134

+CNIH4chr1

224553581

+
intron-3UTRENST00000445658ENST00000366856ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000540147ENST00000465271ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000540147ENST00000366858ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000540147ENST00000366857ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540147ENST00000468318ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540147ENST00000366856ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000584450ENST00000465271ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000584450ENST00000366858ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000584450ENST00000366857ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584450ENST00000468318ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584450ENST00000366856ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000269571ENST00000465271ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000269571ENST00000366858ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000269571ENST00000366857ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000269571ENST00000468318ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000269571ENST00000366856ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000578199ENST00000465271ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000578199ENST00000366858ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000578199ENST00000366857ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000578199ENST00000468318ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000578199ENST00000366856ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000540042ENST00000465271ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000540042ENST00000366858ERBB2chr17

37866134

+CNIH4chr1

224553581

+
Frame-shiftENST00000540042ENST00000366857ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540042ENST00000468318ERBB2chr17

37866134

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540042ENST00000366856ERBB2chr17

37866134

+CNIH4chr1

224553581

+
intron-3CDSENST00000584888ENST00000465271ERBB2chr17

37866134

+CNIH4chr1

224553581

+
intron-3CDSENST00000584888ENST00000366858ERBB2chr17

37866134

+CNIH4chr1

224553581

+
intron-3CDSENST00000584888ENST00000366857ERBB2chr17

37866134

+CNIH4chr1

224553581

+
intron-3UTRENST00000584888ENST00000468318ERBB2chr17

37866134

+CNIH4chr1

224553581

+
intron-3UTRENST00000584888ENST00000366856ERBB2chr17

37866134

+CNIH4chr1

224553581

+
In-frameENST00000584601ENST00000465271ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000584601ENST00000366858ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000584601ENST00000366857ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584601ENST00000468318ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584601ENST00000366856ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000406381ENST00000465271ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000406381ENST00000366858ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000406381ENST00000366857ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000406381ENST00000468318ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000406381ENST00000366856ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000541774ENST00000465271ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000541774ENST00000366858ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000541774ENST00000366857ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000541774ENST00000468318ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000541774ENST00000366856ERBB2chr17

37863394

+CNIH4chr1

224553581

+
intron-3CDSENST00000445658ENST00000465271ERBB2chr17

37863394

+CNIH4chr1

224553581

+
intron-3CDSENST00000445658ENST00000366858ERBB2chr17

37863394

+CNIH4chr1

224553581

+
intron-3CDSENST00000445658ENST00000366857ERBB2chr17

37863394

+CNIH4chr1

224553581

+
intron-3UTRENST00000445658ENST00000468318ERBB2chr17

37863394

+CNIH4chr1

224553581

+
intron-3UTRENST00000445658ENST00000366856ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000540147ENST00000465271ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000540147ENST00000366858ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000540147ENST00000366857ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540147ENST00000468318ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540147ENST00000366856ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000584450ENST00000465271ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000584450ENST00000366858ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000584450ENST00000366857ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584450ENST00000468318ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000584450ENST00000366856ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000269571ENST00000465271ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000269571ENST00000366858ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000269571ENST00000366857ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000269571ENST00000468318ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000269571ENST00000366856ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000578199ENST00000465271ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000578199ENST00000366858ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000578199ENST00000366857ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000578199ENST00000468318ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000578199ENST00000366856ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000540042ENST00000465271ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000540042ENST00000366858ERBB2chr17

37863394

+CNIH4chr1

224553581

+
In-frameENST00000540042ENST00000366857ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540042ENST00000468318ERBB2chr17

37863394

+CNIH4chr1

224553581

+
5CDS-3UTRENST00000540042ENST00000366856ERBB2chr17

37863394

+CNIH4chr1

224553581

+
intron-3CDSENST00000584888ENST00000465271ERBB2chr17

37863394

+CNIH4chr1

224553581

+
intron-3CDSENST00000584888ENST00000366858ERBB2chr17

37863394

+CNIH4chr1

224553581

+
intron-3CDSENST00000584888ENST00000366857ERBB2chr17

37863394

+CNIH4chr1

224553581

+
intron-3UTRENST00000584888ENST00000468318ERBB2chr17

37863394

+CNIH4chr1

224553581

+
intron-3UTRENST00000584888ENST00000366856ERBB2chr17

37863394

+CNIH4chr1

224553581

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000584601ERBB2chr1737863394+ENST00000465271CNIH4chr1224553581+48449327521213153
ENST00000584601ERBB2chr1737863394+ENST00000366858CNIH4chr1224553581+14299327031050115
ENST00000584601ERBB2chr1737863394+ENST00000366857CNIH4chr1224553581+47039327031068121
ENST00000406381ERBB2chr1737863394+ENST00000465271CNIH4chr1224553581+4557645510926138
ENST00000406381ERBB2chr1737863394+ENST00000366858CNIH4chr1224553581+114264546776398
ENST00000406381ERBB2chr1737863394+ENST00000366857CNIH4chr1224553581+4416645467781104
ENST00000541774ERBB2chr1737863394+ENST00000465271CNIH4chr1224553581+40921800461153
ENST00000541774ERBB2chr1737863394+ENST00000366858CNIH4chr1224553581+6771800314104
ENST00000541774ERBB2chr1737863394+ENST00000366857CNIH4chr1224553581+39511800320106
ENST00000540147ERBB2chr1737863394+ENST00000465271CNIH4chr1224553581+437546325744239
ENST00000540147ERBB2chr1737863394+ENST00000366858CNIH4chr1224553581+96046325597190
ENST00000540147ERBB2chr1737863394+ENST00000366857CNIH4chr1224553581+423446325603192
ENST00000584450ERBB2chr1737863394+ENST00000465271CNIH4chr1224553581+43524402721239
ENST00000584450ERBB2chr1737863394+ENST00000366858CNIH4chr1224553581+9374402574190
ENST00000584450ERBB2chr1737863394+ENST00000366857CNIH4chr1224553581+42114402580192
ENST00000269571ERBB2chr1737863394+ENST00000465271CNIH4chr1224553581+429638457665202
ENST00000269571ERBB2chr1737863394+ENST00000366858CNIH4chr1224553581+88138457518153
ENST00000269571ERBB2chr1737863394+ENST00000366857CNIH4chr1224553581+415538457524155
ENST00000578199ERBB2chr1737863394+ENST00000465271CNIH4chr1224553581+4588676541957138
ENST00000578199ERBB2chr1737863394+ENST00000366858CNIH4chr1224553581+117367649879498
ENST00000578199ERBB2chr1737863394+ENST00000366857CNIH4chr1224553581+4447676498812104
ENST00000540042ERBB2chr1737863394+ENST00000465271CNIH4chr1224553581+4213301166582138
ENST00000540042ERBB2chr1737863394+ENST00000366858CNIH4chr1224553581+79830114441991
ENST00000540042ERBB2chr1737863394+ENST00000366857CNIH4chr1224553581+407230114443797

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000584601ENST00000465271ERBB2chr1737863394+CNIH4chr1224553581+0.0578343420.9421657
ENST00000584601ENST00000366858ERBB2chr1737863394+CNIH4chr1224553581+0.133450930.866549
ENST00000584601ENST00000366857ERBB2chr1737863394+CNIH4chr1224553581+0.268470760.73152924
ENST00000406381ENST00000465271ERBB2chr1737863394+CNIH4chr1224553581+0.0607174260.9392826
ENST00000406381ENST00000366858ERBB2chr1737863394+CNIH4chr1224553581+0.173393880.8266061
ENST00000406381ENST00000366857ERBB2chr1737863394+CNIH4chr1224553581+0.284495950.71550405
ENST00000541774ENST00000465271ERBB2chr1737863394+CNIH4chr1224553581+0.056428870.94357115
ENST00000541774ENST00000366858ERBB2chr1737863394+CNIH4chr1224553581+0.129197180.8708028
ENST00000541774ENST00000366857ERBB2chr1737863394+CNIH4chr1224553581+0.276136850.7238631
ENST00000540147ENST00000465271ERBB2chr1737863394+CNIH4chr1224553581+0.0182968660.9817031
ENST00000540147ENST00000366858ERBB2chr1737863394+CNIH4chr1224553581+0.155822780.84417725
ENST00000540147ENST00000366857ERBB2chr1737863394+CNIH4chr1224553581+0.0946049540.90539503
ENST00000584450ENST00000465271ERBB2chr1737863394+CNIH4chr1224553581+0.0180183350.9819817
ENST00000584450ENST00000366858ERBB2chr1737863394+CNIH4chr1224553581+0.131917010.868083
ENST00000584450ENST00000366857ERBB2chr1737863394+CNIH4chr1224553581+0.093326180.90667385
ENST00000269571ENST00000465271ERBB2chr1737863394+CNIH4chr1224553581+0.0172737260.9827262
ENST00000269571ENST00000366858ERBB2chr1737863394+CNIH4chr1224553581+0.080234060.9197659
ENST00000269571ENST00000366857ERBB2chr1737863394+CNIH4chr1224553581+0.090750720.90924925
ENST00000578199ENST00000465271ERBB2chr1737863394+CNIH4chr1224553581+0.0607669240.93923306
ENST00000578199ENST00000366858ERBB2chr1737863394+CNIH4chr1224553581+0.287036270.71296376
ENST00000578199ENST00000366857ERBB2chr1737863394+CNIH4chr1224553581+0.293216080.70678395
ENST00000540042ENST00000465271ERBB2chr1737863394+CNIH4chr1224553581+0.0644635560.93553644
ENST00000540042ENST00000366858ERBB2chr1737863394+CNIH4chr1224553581+0.225711210.77428883
ENST00000540042ENST00000366857ERBB2chr1737863394+CNIH4chr1224553581+0.324222270.67577773

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Fusion Genomic Features for ERBB2-CNIH4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ERBB2chr1737866134+CNIH4chr1224553580+0.312869550.68713045
ERBB2chr1737866734+CNIH4chr1224553580+0.0018226030.9981774
ERBB2chr1737863394+CNIH4chr1224553580+0.001266710.99873334
ERBB2chr1737866134+CNIH4chr1224553580+0.312869550.68713045
ERBB2chr1737866734+CNIH4chr1224553580+0.0018226030.9981774
ERBB2chr1737863394+CNIH4chr1224553580+0.001266710.99873334

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ERBB2-CNIH4


check button Go to

FGviewer for the breakpoints of chr17:37863394-chr1:224553581

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ERBB2

P04626

CNIH4

Q9P003

FUNCTION: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. {ECO:0000305}.; FUNCTION: In the nucleus is involved in transcriptional regulation. Associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. Implicated in transcriptional activation of CDKN1A; the function involves STAT3 and SRC. Involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth. {ECO:0000269|PubMed:10358079, ECO:0000269|PubMed:15380516, ECO:0000269|PubMed:21555369}.FUNCTION: Involved in G protein-coupled receptors (GPCRs) trafficking from the endoplasmic reticulum to the cell surface; it promotes the exit of GPCRs from the early secretory pathway, likely through interaction with the COPII machinery (PubMed:24405750). {ECO:0000269|PubMed:24405750}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCNIH4chr17:37863394chr1:224553581ENST0000036685714118_13846.093.0TransmembraneHelical
TgeneCNIH4chr17:37863394chr1:224553581ENST000003668571457_7746.093.0TransmembraneHelical
TgeneCNIH4chr17:37863394chr1:224553581ENST0000046527115118_13846.0140.0TransmembraneHelical
TgeneCNIH4chr17:37863394chr1:224553581ENST000004652711557_7746.0140.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneERBB2chr17:37863394chr1:224553581ENST00000269571+227720_98775.01256.0DomainProtein kinase
HgeneERBB2chr17:37863394chr1:224553581ENST00000541774+227720_98760.01241.0DomainProtein kinase
HgeneERBB2chr17:37863394chr1:224553581ENST00000269571+227676_68975.01256.0MotifNote=Nuclear localization signal
HgeneERBB2chr17:37863394chr1:224553581ENST00000541774+227676_68960.01241.0MotifNote=Nuclear localization signal
HgeneERBB2chr17:37863394chr1:224553581ENST00000269571+227726_73475.01256.0Nucleotide bindingATP
HgeneERBB2chr17:37863394chr1:224553581ENST00000541774+227726_73460.01241.0Nucleotide bindingATP
HgeneERBB2chr17:37863394chr1:224553581ENST00000269571+22723_65275.01256.0Topological domainExtracellular
HgeneERBB2chr17:37863394chr1:224553581ENST00000269571+227676_125575.01256.0Topological domainCytoplasmic
HgeneERBB2chr17:37863394chr1:224553581ENST00000541774+22723_65260.01241.0Topological domainExtracellular
HgeneERBB2chr17:37863394chr1:224553581ENST00000541774+227676_125560.01241.0Topological domainCytoplasmic
HgeneERBB2chr17:37863394chr1:224553581ENST00000269571+227653_67575.01256.0TransmembraneHelical
HgeneERBB2chr17:37863394chr1:224553581ENST00000541774+227653_67560.01241.0TransmembraneHelical
TgeneCNIH4chr17:37863394chr1:224553581ENST00000366857145_2546.093.0TransmembraneHelical
TgeneCNIH4chr17:37863394chr1:224553581ENST00000465271155_2546.0140.0TransmembraneHelical


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Fusion Gene Sequence for ERBB2-CNIH4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000584601_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4844nt_BP=932nt
AGTACGCAGTCGCGGTACACCGGCTCACGGTCGCCCTGGGAGCCGCTCGCCAGCGCCGCTGCCCCAGCTAGCAGGACCAACCGCGCCGCC
AGGCCGGCCATCCTTTCTCCCTGGCTCGCCGCCGGGGGAGGAGCTTAGGAGTATGAAGCTTCCACTTCCGGAGTAACCGGAAGTTCCTGT
GTTCTTTATTCTACTCTCCGCTGAAGTCCACACAGTTTAAATTAAAGTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCT
GCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGAAGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTT
TTGAGTCGCAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCC
AGCACAGAATTTGGCTTATGCCTACTCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTGGC
AAAGCAAAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCCAGGA
CAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTGTTGTGGACATGCAC
AAAAGTGAGATACTTCAAAGATTCCAGAAGATATGCCCCGGGGGTCCTGGAAGCCACAAGTGTGCACCGGCACAGACATGAAGCTGCGGC
TCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACC
TGCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCAT
TGCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGATACATTATGGTGCCGAGTGGTAACATGGGAGTGT
TTGATCCAACAGAAATACACAATCGAGGGCAGCTGAAGTCACACATGAAAGAAGCCATGATCAAGCTTGGTTTCCACTTGCTCTGCTTCT
TCATGTATCTTTATAGTATGATCTTAGCTTTGATAAATGACTGAAGCTGGAGAAGCCGTGGTTGAAGTCAGCCTACACTACAGTGCACAG
TTGAGGAGCCAGAGACTTCTTAAATCATCCTTAGAACCGTGACCATAGCAGTATATATTTTCCTCTTGGAACAAAAAACTATTTTTGCTG
TATTTTTACCATATAAAGTATTTAAAAAACATGAATTGAGTTTCTGTAGATTTCTAGTTCTCAACTTTAGCCTGAACGCCAACACTTGAA
GGTGTTTTTCATCCTCTGTATGTTGAAGGTGGTTATTTGTATGTAGGAACAGGACTGCCATCCCAGCTTTGCATGCCAAAGAAATAAAGA
ACACACTTTAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAGGTCTACTGAAAAGTTAGAGTACAAAACAACACTGTTGA
TCTGGACAAAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGTGACAACTTCATTTAATATGGTTTAAAGATTTATGAGACTGTCAGCTAA
AAGTCTTTTCACAAGAATGTCAACAGAGAATGGCATCTCAAAATATATATATTTCTTTGCACAATTTGTGAAACCTTATAAGCCATTTTC
CCCAGGTACAATGTAGTTCCTGCTGATAGAAAGGAAATATTTTGTCAAGAGCTTTCATTTAAAAGCTACTACCTCCACAATCACCCCCAA
ACCCAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTATTCCAATTGTATTTGATCTCCCTGATAACGTATTTTCA
TGGGTTTGGGTAGAAGATGCTAATCAGATTAGAAGCAGGAATAGTTATTTGCTGTCTGTGAAATTGAGCCTTTTGGTGCGCCACGTGGTG
CCAGATCAACACTTCTATCCCTCTGCACTGACCACGTTGTGAACTGGGAGACCAAATGCAAGCCATTTCATGGACATAGCAATATACAAC
CAAACTCTGTTCCTTGGAGTTATATTGTAAACTCTTGCAGGTGGGAGAGCAGTTCACCTCCTTAGCTCTGTTTGCCAGCTCTTACAGGGT
AAAATAAACCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCTATCTTAAGCACTGGCATTTGGGCAAAACATGACTGTGT
TCTGTGGGAGAATCCAAAGGCATTATTCACTCTAGTTGAGATAGAATTGGGTGGCTAAACAGGGTGTGTGGTACCCAAAAGATTAAATGT
TACATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAGCCACTAAGCCAAACTCCCTGTGCAGACAGACCATGTTT
CAAGGCTGGAAGTAGTGCCCTGGCAACACACAAAAGGAACGGTGAAATGGTAGGCAAAGTGAACTTGGCTCTGCTGGCCTCTTTGGGGTC
ACAGAAATTGCTCCTTGTGGTAATCTTATATTTCTGTCAGGCACAGGGCCAAGAAGCTGTGTAACAGACATTACTTTGCTTGCATCTCTT
TTTCATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCACTCTGCCTTTCCTCCTAACTTCCTGTGCCTCTTCATGT
TCTGCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTTAAATCCTTGCAACTGAGAGATAAGCTACTTAAAGGCGGTAGAGATCTT
TTTTTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCTTTCT
GGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGCTAGCTACTCCTGGCTAATTTTTGTATTTTTAGTAGAGAT
GGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGATCTGCCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAGG
TGTGAGCCACTGCGCCTGGCCATGTAGATGACTTTTGACCAAAATGTTTCACCTTCTCATTCAGATATTCTTAGTAACCAAAACAGTGAC
TCATGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTACATCAGGCTTGCTGAGGCTAAGCAAATCAGAAAGGTGCCATGTTTATAA
CAGAGGTCAAAGCTCCTTACTTCTGAAACATTAGCTGTGGTTAAAAACAAAAACTCTTCCTTCTTGTATTGCTTGTCTATCAAAGCCAGG
AAAGTGGGGGATCACTGTAGTTAAATTTTTTTTTTTTTTAATTAGAGACAGAGTCTTGCCCTGTCGCCCAAGCTGGAGTGCACTGGCGCA
ATCGTGGTACACTGCAGCCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCCTCAGCTTCCCAAGTAGTTGGGAGTAGGTGCACACCACCA
TGCCCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCTGGTATCAAAATTACTGGCCTCAAGCGATTCTCCTGCCTC
GGCCTCCCAGATGTTGGGATTACTGGTGTGAGCCACCACGCCCAGCTCAAAAACAATTTTTTTAGGGGCACTTCTACAAATCATGAAAGG
GGGATAAAAGCACTGACTTTAAAAAGCCATGTTTAAGATGCTATAAATGTTCTCCCCTTTTCATTGATTGGAGAGTTGTAGAGGACCTTA
GAGATCATTTTGTCTAACTCCCTCATCCCAAAGATAAACTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTG
AGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCT
GAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGG
GAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTT
GTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCTTAGTCCAGTGTT
CTCTCTCCCTTACCACTCCTCTTCCCCTTCCCTCTATAATGGCAGTACCCAGGGCCCGGTCCATAGACTACTATCGAGTGCTCCTATGTG
CATCTTAGTACGTATCATTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTG
AGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGAC
TACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCT
ATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTT

>In-frame_ENST00000584601_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=153AA_start in transcript=752_stop in transcript=1213
MPRGSWKPQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLP

--------------------------------------------------------------
>In-frame_ENST00000584601_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=1429nt_BP=932nt
AGTACGCAGTCGCGGTACACCGGCTCACGGTCGCCCTGGGAGCCGCTCGCCAGCGCCGCTGCCCCAGCTAGCAGGACCAACCGCGCCGCC
AGGCCGGCCATCCTTTCTCCCTGGCTCGCCGCCGGGGGAGGAGCTTAGGAGTATGAAGCTTCCACTTCCGGAGTAACCGGAAGTTCCTGT
GTTCTTTATTCTACTCTCCGCTGAAGTCCACACAGTTTAAATTAAAGTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCT
GCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGAAGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTT
TTGAGTCGCAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCC
AGCACAGAATTTGGCTTATGCCTACTCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTGGC
AAAGCAAAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCCAGGA
CAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTGTTGTGGACATGCAC
AAAAGTGAGATACTTCAAAGATTCCAGAAGATATGCCCCGGGGGTCCTGGAAGCCACAAGTGTGCACCGGCACAGACATGAAGCTGCGGC
TCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACC
TGCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCAT
TGCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTC
GGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCA
CAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCAC
ATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGT

>In-frame_ENST00000584601_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=115AA_start in transcript=703_stop in transcript=1050
MLWTCTKVRYFKDSRRYAPGVLEATSVHRHRHEAAAPCQSRDPPGHAPPPLPGLPGGAGKPGTHLPAHQCQPVLPAVGNSRIDWPYHCHC

--------------------------------------------------------------
>In-frame_ENST00000584601_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4703nt_BP=932nt
AGTACGCAGTCGCGGTACACCGGCTCACGGTCGCCCTGGGAGCCGCTCGCCAGCGCCGCTGCCCCAGCTAGCAGGACCAACCGCGCCGCC
AGGCCGGCCATCCTTTCTCCCTGGCTCGCCGCCGGGGGAGGAGCTTAGGAGTATGAAGCTTCCACTTCCGGAGTAACCGGAAGTTCCTGT
GTTCTTTATTCTACTCTCCGCTGAAGTCCACACAGTTTAAATTAAAGTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCT
GCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGAAGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTT
TTGAGTCGCAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCC
AGCACAGAATTTGGCTTATGCCTACTCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTGGC
AAAGCAAAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCCAGGA
CAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTGTTGTGGACATGCAC
AAAAGTGAGATACTTCAAAGATTCCAGAAGATATGCCCCGGGGGTCCTGGAAGCCACAAGTGTGCACCGGCACAGACATGAAGCTGCGGC
TCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACC
TGCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCAT
TGCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGTATGATCTTAGCTTTGATAAATGACTGAAGCTGGA
GAAGCCGTGGTTGAAGTCAGCCTACACTACAGTGCACAGTTGAGGAGCCAGAGACTTCTTAAATCATCCTTAGAACCGTGACCATAGCAG
TATATATTTTCCTCTTGGAACAAAAAACTATTTTTGCTGTATTTTTACCATATAAAGTATTTAAAAAACATGAATTGAGTTTCTGTAGAT
TTCTAGTTCTCAACTTTAGCCTGAACGCCAACACTTGAAGGTGTTTTTCATCCTCTGTATGTTGAAGGTGGTTATTTGTATGTAGGAACA
GGACTGCCATCCCAGCTTTGCATGCCAAAGAAATAAAGAACACACTTTAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCA
GGTCTACTGAAAAGTTAGAGTACAAAACAACACTGTTGATCTGGACAAAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGTGACAACTTC
ATTTAATATGGTTTAAAGATTTATGAGACTGTCAGCTAAAAGTCTTTTCACAAGAATGTCAACAGAGAATGGCATCTCAAAATATATATA
TTTCTTTGCACAATTTGTGAAACCTTATAAGCCATTTTCCCCAGGTACAATGTAGTTCCTGCTGATAGAAAGGAAATATTTTGTCAAGAG
CTTTCATTTAAAAGCTACTACCTCCACAATCACCCCCAAACCCAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTT
ATTCCAATTGTATTTGATCTCCCTGATAACGTATTTTCATGGGTTTGGGTAGAAGATGCTAATCAGATTAGAAGCAGGAATAGTTATTTG
CTGTCTGTGAAATTGAGCCTTTTGGTGCGCCACGTGGTGCCAGATCAACACTTCTATCCCTCTGCACTGACCACGTTGTGAACTGGGAGA
CCAAATGCAAGCCATTTCATGGACATAGCAATATACAACCAAACTCTGTTCCTTGGAGTTATATTGTAAACTCTTGCAGGTGGGAGAGCA
GTTCACCTCCTTAGCTCTGTTTGCCAGCTCTTACAGGGTAAAATAAACCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGC
TATCTTAAGCACTGGCATTTGGGCAAAACATGACTGTGTTCTGTGGGAGAATCCAAAGGCATTATTCACTCTAGTTGAGATAGAATTGGG
TGGCTAAACAGGGTGTGTGGTACCCAAAAGATTAAATGTTACATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGA
GCCACTAAGCCAAACTCCCTGTGCAGACAGACCATGTTTCAAGGCTGGAAGTAGTGCCCTGGCAACACACAAAAGGAACGGTGAAATGGT
AGGCAAAGTGAACTTGGCTCTGCTGGCCTCTTTGGGGTCACAGAAATTGCTCCTTGTGGTAATCTTATATTTCTGTCAGGCACAGGGCCA
AGAAGCTGTGTAACAGACATTACTTTGCTTGCATCTCTTTTTCATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTC
ACTCTGCCTTTCCTCCTAACTTCCTGTGCCTCTTCATGTTCTGCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTTAAATCCTTG
CAACTGAGAGATAAGCTACTTAAAGGCGGTAGAGATCTTTTTTTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTG
CAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCTTTCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGC
TAGCTACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGA
TCTGCCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCTGGCCATGTAGATGACTTTTGACCAAAATGTTTCA
CCTTCTCATTCAGATATTCTTAGTAACCAAAACAGTGACTCATGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTACATCAGGCTT
GCTGAGGCTAAGCAAATCAGAAAGGTGCCATGTTTATAACAGAGGTCAAAGCTCCTTACTTCTGAAACATTAGCTGTGGTTAAAAACAAA
AACTCTTCCTTCTTGTATTGCTTGTCTATCAAAGCCAGGAAAGTGGGGGATCACTGTAGTTAAATTTTTTTTTTTTTTAATTAGAGACAG
AGTCTTGCCCTGTCGCCCAAGCTGGAGTGCACTGGCGCAATCGTGGTACACTGCAGCCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCC
TCAGCTTCCCAAGTAGTTGGGAGTAGGTGCACACCACCATGCCCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCT
GGTATCAAAATTACTGGCCTCAAGCGATTCTCCTGCCTCGGCCTCCCAGATGTTGGGATTACTGGTGTGAGCCACCACGCCCAGCTCAAA
AACAATTTTTTTAGGGGCACTTCTACAAATCATGAAAGGGGGATAAAAGCACTGACTTTAAAAAGCCATGTTTAAGATGCTATAAATGTT
CTCCCCTTTTCATTGATTGGAGAGTTGTAGAGGACCTTAGAGATCATTTTGTCTAACTCCCTCATCCCAAAGATAAACTGAGGCCTAGAG
ATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAG
GCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGA
ATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGA
ACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGT
AACTGGGAACATCTGAATGCTGAGGCTTAGTCCAGTGTTCTCTCTCCCTTACCACTCCTCTTCCCCTTCCCTCTATAATGGCAGTACCCA
GGGCCCGGTCCATAGACTACTATCGAGTGCTCCTATGTGCATCTTAGTACGTATCATTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGT
GGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTA
GCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGC
TTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGT
TCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCACCTAACACAGTGCCTTGCACACAAACAATAAA

>In-frame_ENST00000584601_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=121AA_start in transcript=703_stop in transcript=1068
MLWTCTKVRYFKDSRRYAPGVLEATSVHRHRHEAAAPCQSRDPPGHAPPPLPGLPGGAGKPGTHLPAHQCQPVLPAVGNSRIDWPYHCHC

--------------------------------------------------------------
>In-frame_ENST00000406381_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4557nt_BP=645nt
GTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGAAGGCGGACGC
CTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGTCGCAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCC
ATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCCAGCACAGAATTTGGCTTATGCCAAATCCGAAAATATTGTGACCAGG
AACCATTCTGTCCAACTCTTCTATTTCAGGTGGCAAAGCAAAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCAC
AGATAAAACGGGGGCACCAGTAGAATGGCCAGGACAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGT
GATGAGAGTGACATGTACTGTTGTGGACATGCACAAAAGTGAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAG
ACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGC
CTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTC
CTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGATACATTATGGTGCCGAGTGGTAACATGGGAGTGTTTGATCCAACAGAAATA
CACAATCGAGGGCAGCTGAAGTCACACATGAAAGAAGCCATGATCAAGCTTGGTTTCCACTTGCTCTGCTTCTTCATGTATCTTTATAGT
ATGATCTTAGCTTTGATAAATGACTGAAGCTGGAGAAGCCGTGGTTGAAGTCAGCCTACACTACAGTGCACAGTTGAGGAGCCAGAGACT
TCTTAAATCATCCTTAGAACCGTGACCATAGCAGTATATATTTTCCTCTTGGAACAAAAAACTATTTTTGCTGTATTTTTACCATATAAA
GTATTTAAAAAACATGAATTGAGTTTCTGTAGATTTCTAGTTCTCAACTTTAGCCTGAACGCCAACACTTGAAGGTGTTTTTCATCCTCT
GTATGTTGAAGGTGGTTATTTGTATGTAGGAACAGGACTGCCATCCCAGCTTTGCATGCCAAAGAAATAAAGAACACACTTTAAAGGGCA
AACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAGGTCTACTGAAAAGTTAGAGTACAAAACAACACTGTTGATCTGGACAAAAGAAGAA
AAATTACCCTTTTTGCTTGTGTTGTGACAACTTCATTTAATATGGTTTAAAGATTTATGAGACTGTCAGCTAAAAGTCTTTTCACAAGAA
TGTCAACAGAGAATGGCATCTCAAAATATATATATTTCTTTGCACAATTTGTGAAACCTTATAAGCCATTTTCCCCAGGTACAATGTAGT
TCCTGCTGATAGAAAGGAAATATTTTGTCAAGAGCTTTCATTTAAAAGCTACTACCTCCACAATCACCCCCAAACCCAGAAAATCCCCAC
TGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTATTCCAATTGTATTTGATCTCCCTGATAACGTATTTTCATGGGTTTGGGTAGAAGA
TGCTAATCAGATTAGAAGCAGGAATAGTTATTTGCTGTCTGTGAAATTGAGCCTTTTGGTGCGCCACGTGGTGCCAGATCAACACTTCTA
TCCCTCTGCACTGACCACGTTGTGAACTGGGAGACCAAATGCAAGCCATTTCATGGACATAGCAATATACAACCAAACTCTGTTCCTTGG
AGTTATATTGTAAACTCTTGCAGGTGGGAGAGCAGTTCACCTCCTTAGCTCTGTTTGCCAGCTCTTACAGGGTAAAATAAACCTGGCAAT
TTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCTATCTTAAGCACTGGCATTTGGGCAAAACATGACTGTGTTCTGTGGGAGAATCCAA
AGGCATTATTCACTCTAGTTGAGATAGAATTGGGTGGCTAAACAGGGTGTGTGGTACCCAAAAGATTAAATGTTACATGTCCTTTTAGTC
CTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAGCCACTAAGCCAAACTCCCTGTGCAGACAGACCATGTTTCAAGGCTGGAAGTAGTG
CCCTGGCAACACACAAAAGGAACGGTGAAATGGTAGGCAAAGTGAACTTGGCTCTGCTGGCCTCTTTGGGGTCACAGAAATTGCTCCTTG
TGGTAATCTTATATTTCTGTCAGGCACAGGGCCAAGAAGCTGTGTAACAGACATTACTTTGCTTGCATCTCTTTTTCATACCTTTTCCCT
CTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCACTCTGCCTTTCCTCCTAACTTCCTGTGCCTCTTCATGTTCTGCTCAAGCTTTTTA
AAGCAACGAAGCTGTTGGAGAACTTAAATCCTTGCAACTGAGAGATAAGCTACTTAAAGGCGGTAGAGATCTTTTTTTTTTTTTTTTTGA
GATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCTTTCTGGGTTCAAGCGATTCTC
CTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGCTAGCTACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTG
GCCAGGCTGGTCTCAAACTCCTGACCTCAAACGATCTGCCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCT
GGCCATGTAGATGACTTTTGACCAAAATGTTTCACCTTCTCATTCAGATATTCTTAGTAACCAAAACAGTGACTCATGCAGTTGAGAGAG
CCTTTGGGCTGTCAGTTTACAGTACATCAGGCTTGCTGAGGCTAAGCAAATCAGAAAGGTGCCATGTTTATAACAGAGGTCAAAGCTCCT
TACTTCTGAAACATTAGCTGTGGTTAAAAACAAAAACTCTTCCTTCTTGTATTGCTTGTCTATCAAAGCCAGGAAAGTGGGGGATCACTG
TAGTTAAATTTTTTTTTTTTTTAATTAGAGACAGAGTCTTGCCCTGTCGCCCAAGCTGGAGTGCACTGGCGCAATCGTGGTACACTGCAG
CCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCCTCAGCTTCCCAAGTAGTTGGGAGTAGGTGCACACCACCATGCCCAGCGAATTTTTT
GTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCTGGTATCAAAATTACTGGCCTCAAGCGATTCTCCTGCCTCGGCCTCCCAGATGTTGG
GATTACTGGTGTGAGCCACCACGCCCAGCTCAAAAACAATTTTTTTAGGGGCACTTCTACAAATCATGAAAGGGGGATAAAAGCACTGAC
TTTAAAAAGCCATGTTTAAGATGCTATAAATGTTCTCCCCTTTTCATTGATTGGAGAGTTGTAGAGGACCTTAGAGATCATTTTGTCTAA
CTCCCTCATCCCAAAGATAAACTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTC
AGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGA
GATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGA
GGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTG
AATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCTTAGTCCAGTGTTCTCTCTCCCTTACCACT
CCTCTTCCCCTTCCCTCTATAATGGCAGTACCCAGGGCCCGGTCCATAGACTACTATCGAGTGCTCCTATGTGCATCTTAGTACGTATCA
TTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCG
AAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACAAAACC
TGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTACAGTTA
TTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGG

>In-frame_ENST00000406381_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=138AA_start in transcript=510_stop in transcript=926
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATWNIYRYIMVPSG

--------------------------------------------------------------
>In-frame_ENST00000406381_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=1142nt_BP=645nt
GTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGAAGGCGGACGC
CTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGTCGCAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCC
ATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCCAGCACAGAATTTGGCTTATGCCAAATCCGAAAATATTGTGACCAGG
AACCATTCTGTCCAACTCTTCTATTTCAGGTGGCAAAGCAAAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCAC
AGATAAAACGGGGGCACCAGTAGAATGGCCAGGACAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGT
GATGAGAGTGACATGTACTGTTGTGGACATGCACAAAAGTGAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAG
ACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGC
CTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTC
CTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGG
AAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACA
AAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTAC
AGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCT

>In-frame_ENST00000406381_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=98AA_start in transcript=467_stop in transcript=763
MLWTCTKVSVHRHRHEAAAPCQSRDPPGHAPPPLPGLPGGAGKPGTHLPAHQCQPVLPAVGNSRIDWPYHCHCITAHVIALVHLPSQLTC

--------------------------------------------------------------
>In-frame_ENST00000406381_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4416nt_BP=645nt
GTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGAAGGCGGACGC
CTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGTCGCAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCC
ATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCCAGCACAGAATTTGGCTTATGCCAAATCCGAAAATATTGTGACCAGG
AACCATTCTGTCCAACTCTTCTATTTCAGGTGGCAAAGCAAAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCAC
AGATAAAACGGGGGCACCAGTAGAATGGCCAGGACAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGT
GATGAGAGTGACATGTACTGTTGTGGACATGCACAAAAGTGAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAG
ACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGC
CTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTC
CTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGTATGATCTTAGCTTTGATAAATGACTGAAGCTGGAGAAGCCGTGGTTGAAGT
CAGCCTACACTACAGTGCACAGTTGAGGAGCCAGAGACTTCTTAAATCATCCTTAGAACCGTGACCATAGCAGTATATATTTTCCTCTTG
GAACAAAAAACTATTTTTGCTGTATTTTTACCATATAAAGTATTTAAAAAACATGAATTGAGTTTCTGTAGATTTCTAGTTCTCAACTTT
AGCCTGAACGCCAACACTTGAAGGTGTTTTTCATCCTCTGTATGTTGAAGGTGGTTATTTGTATGTAGGAACAGGACTGCCATCCCAGCT
TTGCATGCCAAAGAAATAAAGAACACACTTTAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAGGTCTACTGAAAAGTTA
GAGTACAAAACAACACTGTTGATCTGGACAAAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGTGACAACTTCATTTAATATGGTTTAAA
GATTTATGAGACTGTCAGCTAAAAGTCTTTTCACAAGAATGTCAACAGAGAATGGCATCTCAAAATATATATATTTCTTTGCACAATTTG
TGAAACCTTATAAGCCATTTTCCCCAGGTACAATGTAGTTCCTGCTGATAGAAAGGAAATATTTTGTCAAGAGCTTTCATTTAAAAGCTA
CTACCTCCACAATCACCCCCAAACCCAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTATTCCAATTGTATTTGA
TCTCCCTGATAACGTATTTTCATGGGTTTGGGTAGAAGATGCTAATCAGATTAGAAGCAGGAATAGTTATTTGCTGTCTGTGAAATTGAG
CCTTTTGGTGCGCCACGTGGTGCCAGATCAACACTTCTATCCCTCTGCACTGACCACGTTGTGAACTGGGAGACCAAATGCAAGCCATTT
CATGGACATAGCAATATACAACCAAACTCTGTTCCTTGGAGTTATATTGTAAACTCTTGCAGGTGGGAGAGCAGTTCACCTCCTTAGCTC
TGTTTGCCAGCTCTTACAGGGTAAAATAAACCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCTATCTTAAGCACTGGCA
TTTGGGCAAAACATGACTGTGTTCTGTGGGAGAATCCAAAGGCATTATTCACTCTAGTTGAGATAGAATTGGGTGGCTAAACAGGGTGTG
TGGTACCCAAAAGATTAAATGTTACATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAGCCACTAAGCCAAACTC
CCTGTGCAGACAGACCATGTTTCAAGGCTGGAAGTAGTGCCCTGGCAACACACAAAAGGAACGGTGAAATGGTAGGCAAAGTGAACTTGG
CTCTGCTGGCCTCTTTGGGGTCACAGAAATTGCTCCTTGTGGTAATCTTATATTTCTGTCAGGCACAGGGCCAAGAAGCTGTGTAACAGA
CATTACTTTGCTTGCATCTCTTTTTCATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCACTCTGCCTTTCCTCCT
AACTTCCTGTGCCTCTTCATGTTCTGCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTTAAATCCTTGCAACTGAGAGATAAGCT
ACTTAAAGGCGGTAGAGATCTTTTTTTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAG
CTCACTGCAACCTCTGCTTTCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGCTAGCTACTCCTGGCTAA
TTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGATCTGCCTGCCTTGGTCT
CCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCTGGCCATGTAGATGACTTTTGACCAAAATGTTTCACCTTCTCATTCAGATAT
TCTTAGTAACCAAAACAGTGACTCATGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTACATCAGGCTTGCTGAGGCTAAGCAAAT
CAGAAAGGTGCCATGTTTATAACAGAGGTCAAAGCTCCTTACTTCTGAAACATTAGCTGTGGTTAAAAACAAAAACTCTTCCTTCTTGTA
TTGCTTGTCTATCAAAGCCAGGAAAGTGGGGGATCACTGTAGTTAAATTTTTTTTTTTTTTAATTAGAGACAGAGTCTTGCCCTGTCGCC
CAAGCTGGAGTGCACTGGCGCAATCGTGGTACACTGCAGCCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCCTCAGCTTCCCAAGTAGT
TGGGAGTAGGTGCACACCACCATGCCCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCTGGTATCAAAATTACTGG
CCTCAAGCGATTCTCCTGCCTCGGCCTCCCAGATGTTGGGATTACTGGTGTGAGCCACCACGCCCAGCTCAAAAACAATTTTTTTAGGGG
CACTTCTACAAATCATGAAAGGGGGATAAAAGCACTGACTTTAAAAAGCCATGTTTAAGATGCTATAAATGTTCTCCCCTTTTCATTGAT
TGGAGAGTTGTAGAGGACCTTAGAGATCATTTTGTCTAACTCCCTCATCCCAAAGATAAACTGAGGCCTAGAGATCGTTCAGGGTGTTGT
AACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAG
GGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGA
TCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGG
CCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAA
TGCTGAGGCTTAGTCCAGTGTTCTCTCTCCCTTACCACTCCTCTTCCCCTTCCCTCTATAATGGCAGTACCCAGGGCCCGGTCCATAGAC
TACTATCGAGTGCTCCTATGTGCATCTTAGTACGTATCATTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTGGTAGCAACTGCCCTTG
CTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTG
CCTTTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCT
CCCATGGCACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATA
TGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCACCTAACACAGTGCCTTGCACACAAACAATAAATGATTGTTGAGTGAATA

>In-frame_ENST00000406381_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=104AA_start in transcript=467_stop in transcript=781
MLWTCTKVSVHRHRHEAAAPCQSRDPPGHAPPPLPGLPGGAGKPGTHLPAHQCQPVLPAVGNSRIDWPYHCHCITAHVIALVHLPSQLTC

--------------------------------------------------------------
>In-frame_ENST00000541774_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4092nt_BP=180nt
ATGCCCCGGGGGTCCTGGAAGCCACAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATG
CTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAG
TGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTCCTTCTCAACTTACCT
GTTGCCACTTGGAATATATATCGATACATTATGGTGCCGAGTGGTAACATGGGAGTGTTTGATCCAACAGAAATACACAATCGAGGGCAG
CTGAAGTCACACATGAAAGAAGCCATGATCAAGCTTGGTTTCCACTTGCTCTGCTTCTTCATGTATCTTTATAGTATGATCTTAGCTTTG
ATAAATGACTGAAGCTGGAGAAGCCGTGGTTGAAGTCAGCCTACACTACAGTGCACAGTTGAGGAGCCAGAGACTTCTTAAATCATCCTT
AGAACCGTGACCATAGCAGTATATATTTTCCTCTTGGAACAAAAAACTATTTTTGCTGTATTTTTACCATATAAAGTATTTAAAAAACAT
GAATTGAGTTTCTGTAGATTTCTAGTTCTCAACTTTAGCCTGAACGCCAACACTTGAAGGTGTTTTTCATCCTCTGTATGTTGAAGGTGG
TTATTTGTATGTAGGAACAGGACTGCCATCCCAGCTTTGCATGCCAAAGAAATAAAGAACACACTTTAAAGGGCAAACTGAAGAGATGAG
CGAGCAAAGGTGCCCTTCAGGTCTACTGAAAAGTTAGAGTACAAAACAACACTGTTGATCTGGACAAAAGAAGAAAAATTACCCTTTTTG
CTTGTGTTGTGACAACTTCATTTAATATGGTTTAAAGATTTATGAGACTGTCAGCTAAAAGTCTTTTCACAAGAATGTCAACAGAGAATG
GCATCTCAAAATATATATATTTCTTTGCACAATTTGTGAAACCTTATAAGCCATTTTCCCCAGGTACAATGTAGTTCCTGCTGATAGAAA
GGAAATATTTTGTCAAGAGCTTTCATTTAAAAGCTACTACCTCCACAATCACCCCCAAACCCAGAAAATCCCCACTGGCTCTTGCCAGTC
TGGTTTTCGTATTGCAGTTATTCCAATTGTATTTGATCTCCCTGATAACGTATTTTCATGGGTTTGGGTAGAAGATGCTAATCAGATTAG
AAGCAGGAATAGTTATTTGCTGTCTGTGAAATTGAGCCTTTTGGTGCGCCACGTGGTGCCAGATCAACACTTCTATCCCTCTGCACTGAC
CACGTTGTGAACTGGGAGACCAAATGCAAGCCATTTCATGGACATAGCAATATACAACCAAACTCTGTTCCTTGGAGTTATATTGTAAAC
TCTTGCAGGTGGGAGAGCAGTTCACCTCCTTAGCTCTGTTTGCCAGCTCTTACAGGGTAAAATAAACCTGGCAATTTATCCTCAGTCCTA
GTTTGTGGTTTAATGTTGCTATCTTAAGCACTGGCATTTGGGCAAAACATGACTGTGTTCTGTGGGAGAATCCAAAGGCATTATTCACTC
TAGTTGAGATAGAATTGGGTGGCTAAACAGGGTGTGTGGTACCCAAAAGATTAAATGTTACATGTCCTTTTAGTCCTTGACCAGGTCTAG
CCTTGGCAGAAGCAAGGGAGCCACTAAGCCAAACTCCCTGTGCAGACAGACCATGTTTCAAGGCTGGAAGTAGTGCCCTGGCAACACACA
AAAGGAACGGTGAAATGGTAGGCAAAGTGAACTTGGCTCTGCTGGCCTCTTTGGGGTCACAGAAATTGCTCCTTGTGGTAATCTTATATT
TCTGTCAGGCACAGGGCCAAGAAGCTGTGTAACAGACATTACTTTGCTTGCATCTCTTTTTCATACCTTTTCCCTCTGAGGCAGCTTTTG
CTTAGAAAACAGTCCCTTCACTCTGCCTTTCCTCCTAACTTCCTGTGCCTCTTCATGTTCTGCTCAAGCTTTTTAAAGCAACGAAGCTGT
TGGAGAACTTAAATCCTTGCAACTGAGAGATAAGCTACTTAAAGGCGGTAGAGATCTTTTTTTTTTTTTTTTTGAGATGGGGTCTTGCTG
TGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCTTTCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCC
AAGTAGCTGGGATTACGGCTAGCTACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCA
AACTCCTGACCTCAAACGATCTGCCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCTGGCCATGTAGATGAC
TTTTGACCAAAATGTTTCACCTTCTCATTCAGATATTCTTAGTAACCAAAACAGTGACTCATGCAGTTGAGAGAGCCTTTGGGCTGTCAG
TTTACAGTACATCAGGCTTGCTGAGGCTAAGCAAATCAGAAAGGTGCCATGTTTATAACAGAGGTCAAAGCTCCTTACTTCTGAAACATT
AGCTGTGGTTAAAAACAAAAACTCTTCCTTCTTGTATTGCTTGTCTATCAAAGCCAGGAAAGTGGGGGATCACTGTAGTTAAATTTTTTT
TTTTTTTAATTAGAGACAGAGTCTTGCCCTGTCGCCCAAGCTGGAGTGCACTGGCGCAATCGTGGTACACTGCAGCCTTGAACTCCTGGA
CTCAAGCAGTCCTCCTGCCTCAGCTTCCCAAGTAGTTGGGAGTAGGTGCACACCACCATGCCCAGCGAATTTTTTGTAGAGACAGAGGTC
TTGCTATGTTGCCTAGGCTGGTATCAAAATTACTGGCCTCAAGCGATTCTCCTGCCTCGGCCTCCCAGATGTTGGGATTACTGGTGTGAG
CCACCACGCCCAGCTCAAAAACAATTTTTTTAGGGGCACTTCTACAAATCATGAAAGGGGGATAAAAGCACTGACTTTAAAAAGCCATGT
TTAAGATGCTATAAATGTTCTCCCCTTTTCATTGATTGGAGAGTTGTAGAGGACCTTAGAGATCATTTTGTCTAACTCCCTCATCCCAAA
GATAAACTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTG
GGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGT
TGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTT
CAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAG
AGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCTTAGTCCAGTGTTCTCTCTCCCTTACCACTCCTCTTCCCCTTCCC
TCTATAATGGCAGTACCCAGGGCCCGGTCCATAGACTACTATCGAGTGCTCCTATGTGCATCTTAGTACGTATCATTTTCCCTTGCCTTT
TTCCTTCTATCCTTTCAGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAG
CTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGA
AGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAA
TCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCACCTAACACAGTGC

>In-frame_ENST00000541774_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=153AA_start in transcript=0_stop in transcript=461
MPRGSWKPQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLP

--------------------------------------------------------------
>In-frame_ENST00000541774_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=677nt_BP=180nt
ATGCCCCGGGGGTCCTGGAAGCCACAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATG
CTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAG
TGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTCCTTCTCAACTTACCT
GTTGCCACTTGGAATATATATCGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGA
TGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTC
TTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCA
ATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCACCTAACAC

>In-frame_ENST00000541774_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=104AA_start in transcript=0_stop in transcript=314
MPRGSWKPQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLP

--------------------------------------------------------------
>In-frame_ENST00000541774_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=3951nt_BP=180nt
ATGCCCCGGGGGTCCTGGAAGCCACAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATG
CTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAG
TGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTCCTTCTCAACTTACCT
GTTGCCACTTGGAATATATATCGTATGATCTTAGCTTTGATAAATGACTGAAGCTGGAGAAGCCGTGGTTGAAGTCAGCCTACACTACAG
TGCACAGTTGAGGAGCCAGAGACTTCTTAAATCATCCTTAGAACCGTGACCATAGCAGTATATATTTTCCTCTTGGAACAAAAAACTATT
TTTGCTGTATTTTTACCATATAAAGTATTTAAAAAACATGAATTGAGTTTCTGTAGATTTCTAGTTCTCAACTTTAGCCTGAACGCCAAC
ACTTGAAGGTGTTTTTCATCCTCTGTATGTTGAAGGTGGTTATTTGTATGTAGGAACAGGACTGCCATCCCAGCTTTGCATGCCAAAGAA
ATAAAGAACACACTTTAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAGGTCTACTGAAAAGTTAGAGTACAAAACAACA
CTGTTGATCTGGACAAAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGTGACAACTTCATTTAATATGGTTTAAAGATTTATGAGACTGT
CAGCTAAAAGTCTTTTCACAAGAATGTCAACAGAGAATGGCATCTCAAAATATATATATTTCTTTGCACAATTTGTGAAACCTTATAAGC
CATTTTCCCCAGGTACAATGTAGTTCCTGCTGATAGAAAGGAAATATTTTGTCAAGAGCTTTCATTTAAAAGCTACTACCTCCACAATCA
CCCCCAAACCCAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTATTCCAATTGTATTTGATCTCCCTGATAACGT
ATTTTCATGGGTTTGGGTAGAAGATGCTAATCAGATTAGAAGCAGGAATAGTTATTTGCTGTCTGTGAAATTGAGCCTTTTGGTGCGCCA
CGTGGTGCCAGATCAACACTTCTATCCCTCTGCACTGACCACGTTGTGAACTGGGAGACCAAATGCAAGCCATTTCATGGACATAGCAAT
ATACAACCAAACTCTGTTCCTTGGAGTTATATTGTAAACTCTTGCAGGTGGGAGAGCAGTTCACCTCCTTAGCTCTGTTTGCCAGCTCTT
ACAGGGTAAAATAAACCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCTATCTTAAGCACTGGCATTTGGGCAAAACATG
ACTGTGTTCTGTGGGAGAATCCAAAGGCATTATTCACTCTAGTTGAGATAGAATTGGGTGGCTAAACAGGGTGTGTGGTACCCAAAAGAT
TAAATGTTACATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAGCCACTAAGCCAAACTCCCTGTGCAGACAGAC
CATGTTTCAAGGCTGGAAGTAGTGCCCTGGCAACACACAAAAGGAACGGTGAAATGGTAGGCAAAGTGAACTTGGCTCTGCTGGCCTCTT
TGGGGTCACAGAAATTGCTCCTTGTGGTAATCTTATATTTCTGTCAGGCACAGGGCCAAGAAGCTGTGTAACAGACATTACTTTGCTTGC
ATCTCTTTTTCATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCACTCTGCCTTTCCTCCTAACTTCCTGTGCCTC
TTCATGTTCTGCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTTAAATCCTTGCAACTGAGAGATAAGCTACTTAAAGGCGGTAG
AGATCTTTTTTTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCT
GCTTTCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGCTAGCTACTCCTGGCTAATTTTTGTATTTTTAG
TAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGATCTGCCTGCCTTGGTCTCCCAAAGTGCTGGGA
TTATAGGTGTGAGCCACTGCGCCTGGCCATGTAGATGACTTTTGACCAAAATGTTTCACCTTCTCATTCAGATATTCTTAGTAACCAAAA
CAGTGACTCATGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTACATCAGGCTTGCTGAGGCTAAGCAAATCAGAAAGGTGCCATG
TTTATAACAGAGGTCAAAGCTCCTTACTTCTGAAACATTAGCTGTGGTTAAAAACAAAAACTCTTCCTTCTTGTATTGCTTGTCTATCAA
AGCCAGGAAAGTGGGGGATCACTGTAGTTAAATTTTTTTTTTTTTTAATTAGAGACAGAGTCTTGCCCTGTCGCCCAAGCTGGAGTGCAC
TGGCGCAATCGTGGTACACTGCAGCCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCCTCAGCTTCCCAAGTAGTTGGGAGTAGGTGCAC
ACCACCATGCCCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCTGGTATCAAAATTACTGGCCTCAAGCGATTCTC
CTGCCTCGGCCTCCCAGATGTTGGGATTACTGGTGTGAGCCACCACGCCCAGCTCAAAAACAATTTTTTTAGGGGCACTTCTACAAATCA
TGAAAGGGGGATAAAAGCACTGACTTTAAAAAGCCATGTTTAAGATGCTATAAATGTTCTCCCCTTTTCATTGATTGGAGAGTTGTAGAG
GACCTTAGAGATCATTTTGTCTAACTCCCTCATCCCAAAGATAAACTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTG
AATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGG
AACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTG
TAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCA
GGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCTTAGTC
CAGTGTTCTCTCTCCCTTACCACTCCTCTTCCCCTTCCCTCTATAATGGCAGTACCCAGGGCCCGGTCCATAGACTACTATCGAGTGCTC
CTATGTGCATCTTAGTACGTATCATTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTGGTAGCAACTGCCCTTGCTAATCACCGTAACC
TCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGC
CACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACC
ACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTT

>In-frame_ENST00000541774_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=106AA_start in transcript=0_stop in transcript=320
MPRGSWKPQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLP

--------------------------------------------------------------
>In-frame_ENST00000540147_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4375nt_BP=463nt
GGAGGAGGTGGAGGAGGAGGGCTGCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCGGAGAAACCAG
GGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAGCACCCCGCGCC
CCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGCCGCTGGGGGCT
CCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGAC
CCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCT
GTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTCCT
TCTCAACTTACCTGTTGCCACTTGGAATATATATCGATACATTATGGTGCCGAGTGGTAACATGGGAGTGTTTGATCCAACAGAAATACA
CAATCGAGGGCAGCTGAAGTCACACATGAAAGAAGCCATGATCAAGCTTGGTTTCCACTTGCTCTGCTTCTTCATGTATCTTTATAGTAT
GATCTTAGCTTTGATAAATGACTGAAGCTGGAGAAGCCGTGGTTGAAGTCAGCCTACACTACAGTGCACAGTTGAGGAGCCAGAGACTTC
TTAAATCATCCTTAGAACCGTGACCATAGCAGTATATATTTTCCTCTTGGAACAAAAAACTATTTTTGCTGTATTTTTACCATATAAAGT
ATTTAAAAAACATGAATTGAGTTTCTGTAGATTTCTAGTTCTCAACTTTAGCCTGAACGCCAACACTTGAAGGTGTTTTTCATCCTCTGT
ATGTTGAAGGTGGTTATTTGTATGTAGGAACAGGACTGCCATCCCAGCTTTGCATGCCAAAGAAATAAAGAACACACTTTAAAGGGCAAA
CTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAGGTCTACTGAAAAGTTAGAGTACAAAACAACACTGTTGATCTGGACAAAAGAAGAAAA
ATTACCCTTTTTGCTTGTGTTGTGACAACTTCATTTAATATGGTTTAAAGATTTATGAGACTGTCAGCTAAAAGTCTTTTCACAAGAATG
TCAACAGAGAATGGCATCTCAAAATATATATATTTCTTTGCACAATTTGTGAAACCTTATAAGCCATTTTCCCCAGGTACAATGTAGTTC
CTGCTGATAGAAAGGAAATATTTTGTCAAGAGCTTTCATTTAAAAGCTACTACCTCCACAATCACCCCCAAACCCAGAAAATCCCCACTG
GCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTATTCCAATTGTATTTGATCTCCCTGATAACGTATTTTCATGGGTTTGGGTAGAAGATG
CTAATCAGATTAGAAGCAGGAATAGTTATTTGCTGTCTGTGAAATTGAGCCTTTTGGTGCGCCACGTGGTGCCAGATCAACACTTCTATC
CCTCTGCACTGACCACGTTGTGAACTGGGAGACCAAATGCAAGCCATTTCATGGACATAGCAATATACAACCAAACTCTGTTCCTTGGAG
TTATATTGTAAACTCTTGCAGGTGGGAGAGCAGTTCACCTCCTTAGCTCTGTTTGCCAGCTCTTACAGGGTAAAATAAACCTGGCAATTT
ATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCTATCTTAAGCACTGGCATTTGGGCAAAACATGACTGTGTTCTGTGGGAGAATCCAAAG
GCATTATTCACTCTAGTTGAGATAGAATTGGGTGGCTAAACAGGGTGTGTGGTACCCAAAAGATTAAATGTTACATGTCCTTTTAGTCCT
TGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAGCCACTAAGCCAAACTCCCTGTGCAGACAGACCATGTTTCAAGGCTGGAAGTAGTGCC
CTGGCAACACACAAAAGGAACGGTGAAATGGTAGGCAAAGTGAACTTGGCTCTGCTGGCCTCTTTGGGGTCACAGAAATTGCTCCTTGTG
GTAATCTTATATTTCTGTCAGGCACAGGGCCAAGAAGCTGTGTAACAGACATTACTTTGCTTGCATCTCTTTTTCATACCTTTTCCCTCT
GAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCACTCTGCCTTTCCTCCTAACTTCCTGTGCCTCTTCATGTTCTGCTCAAGCTTTTTAAA
GCAACGAAGCTGTTGGAGAACTTAAATCCTTGCAACTGAGAGATAAGCTACTTAAAGGCGGTAGAGATCTTTTTTTTTTTTTTTTTGAGA
TGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCTTTCTGGGTTCAAGCGATTCTCCT
GCCTCAGCCTCCCAAGTAGCTGGGATTACGGCTAGCTACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGC
CAGGCTGGTCTCAAACTCCTGACCTCAAACGATCTGCCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCTGG
CCATGTAGATGACTTTTGACCAAAATGTTTCACCTTCTCATTCAGATATTCTTAGTAACCAAAACAGTGACTCATGCAGTTGAGAGAGCC
TTTGGGCTGTCAGTTTACAGTACATCAGGCTTGCTGAGGCTAAGCAAATCAGAAAGGTGCCATGTTTATAACAGAGGTCAAAGCTCCTTA
CTTCTGAAACATTAGCTGTGGTTAAAAACAAAAACTCTTCCTTCTTGTATTGCTTGTCTATCAAAGCCAGGAAAGTGGGGGATCACTGTA
GTTAAATTTTTTTTTTTTTTAATTAGAGACAGAGTCTTGCCCTGTCGCCCAAGCTGGAGTGCACTGGCGCAATCGTGGTACACTGCAGCC
TTGAACTCCTGGACTCAAGCAGTCCTCCTGCCTCAGCTTCCCAAGTAGTTGGGAGTAGGTGCACACCACCATGCCCAGCGAATTTTTTGT
AGAGACAGAGGTCTTGCTATGTTGCCTAGGCTGGTATCAAAATTACTGGCCTCAAGCGATTCTCCTGCCTCGGCCTCCCAGATGTTGGGA
TTACTGGTGTGAGCCACCACGCCCAGCTCAAAAACAATTTTTTTAGGGGCACTTCTACAAATCATGAAAGGGGGATAAAAGCACTGACTT
TAAAAAGCCATGTTTAAGATGCTATAAATGTTCTCCCCTTTTCATTGATTGGAGAGTTGTAGAGGACCTTAGAGATCATTTTGTCTAACT
CCCTCATCCCAAAGATAAACTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAG
GGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGA
TCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGG
CCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAA
TGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCTTAGTCCAGTGTTCTCTCTCCCTTACCACTCC
TCTTCCCCTTCCCTCTATAATGGCAGTACCCAGGGCCCGGTCCATAGACTACTATCGAGTGCTCCTATGTGCATCTTAGTACGTATCATT
TTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAA
ATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTG
ACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTACAGTTATT
TGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCA

>In-frame_ENST00000540147_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=239AA_start in transcript=25_stop in transcript=744
MRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATW

--------------------------------------------------------------
>In-frame_ENST00000540147_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=960nt_BP=463nt
GGAGGAGGTGGAGGAGGAGGGCTGCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCGGAGAAACCAG
GGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAGCACCCCGCGCC
CCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGCCGCTGGGGGCT
CCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGAC
CCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCT
GTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTCCT
TCTCAACTTACCTGTTGCCACTTGGAATATATATCGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAA
GCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACAAA
ACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTACAG
TTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCT

>In-frame_ENST00000540147_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=190AA_start in transcript=25_stop in transcript=597
MRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATW

--------------------------------------------------------------
>In-frame_ENST00000540147_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4234nt_BP=463nt
GGAGGAGGTGGAGGAGGAGGGCTGCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCGGAGAAACCAG
GGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAGCACCCCGCGCC
CCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGCCGCTGGGGGCT
CCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGAC
CCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCT
GTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTCCT
TCTCAACTTACCTGTTGCCACTTGGAATATATATCGTATGATCTTAGCTTTGATAAATGACTGAAGCTGGAGAAGCCGTGGTTGAAGTCA
GCCTACACTACAGTGCACAGTTGAGGAGCCAGAGACTTCTTAAATCATCCTTAGAACCGTGACCATAGCAGTATATATTTTCCTCTTGGA
ACAAAAAACTATTTTTGCTGTATTTTTACCATATAAAGTATTTAAAAAACATGAATTGAGTTTCTGTAGATTTCTAGTTCTCAACTTTAG
CCTGAACGCCAACACTTGAAGGTGTTTTTCATCCTCTGTATGTTGAAGGTGGTTATTTGTATGTAGGAACAGGACTGCCATCCCAGCTTT
GCATGCCAAAGAAATAAAGAACACACTTTAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAGGTCTACTGAAAAGTTAGA
GTACAAAACAACACTGTTGATCTGGACAAAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGTGACAACTTCATTTAATATGGTTTAAAGA
TTTATGAGACTGTCAGCTAAAAGTCTTTTCACAAGAATGTCAACAGAGAATGGCATCTCAAAATATATATATTTCTTTGCACAATTTGTG
AAACCTTATAAGCCATTTTCCCCAGGTACAATGTAGTTCCTGCTGATAGAAAGGAAATATTTTGTCAAGAGCTTTCATTTAAAAGCTACT
ACCTCCACAATCACCCCCAAACCCAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTATTCCAATTGTATTTGATC
TCCCTGATAACGTATTTTCATGGGTTTGGGTAGAAGATGCTAATCAGATTAGAAGCAGGAATAGTTATTTGCTGTCTGTGAAATTGAGCC
TTTTGGTGCGCCACGTGGTGCCAGATCAACACTTCTATCCCTCTGCACTGACCACGTTGTGAACTGGGAGACCAAATGCAAGCCATTTCA
TGGACATAGCAATATACAACCAAACTCTGTTCCTTGGAGTTATATTGTAAACTCTTGCAGGTGGGAGAGCAGTTCACCTCCTTAGCTCTG
TTTGCCAGCTCTTACAGGGTAAAATAAACCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCTATCTTAAGCACTGGCATT
TGGGCAAAACATGACTGTGTTCTGTGGGAGAATCCAAAGGCATTATTCACTCTAGTTGAGATAGAATTGGGTGGCTAAACAGGGTGTGTG
GTACCCAAAAGATTAAATGTTACATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAGCCACTAAGCCAAACTCCC
TGTGCAGACAGACCATGTTTCAAGGCTGGAAGTAGTGCCCTGGCAACACACAAAAGGAACGGTGAAATGGTAGGCAAAGTGAACTTGGCT
CTGCTGGCCTCTTTGGGGTCACAGAAATTGCTCCTTGTGGTAATCTTATATTTCTGTCAGGCACAGGGCCAAGAAGCTGTGTAACAGACA
TTACTTTGCTTGCATCTCTTTTTCATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCACTCTGCCTTTCCTCCTAA
CTTCCTGTGCCTCTTCATGTTCTGCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTTAAATCCTTGCAACTGAGAGATAAGCTAC
TTAAAGGCGGTAGAGATCTTTTTTTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCT
CACTGCAACCTCTGCTTTCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGCTAGCTACTCCTGGCTAATT
TTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGATCTGCCTGCCTTGGTCTCC
CAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCTGGCCATGTAGATGACTTTTGACCAAAATGTTTCACCTTCTCATTCAGATATTC
TTAGTAACCAAAACAGTGACTCATGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTACATCAGGCTTGCTGAGGCTAAGCAAATCA
GAAAGGTGCCATGTTTATAACAGAGGTCAAAGCTCCTTACTTCTGAAACATTAGCTGTGGTTAAAAACAAAAACTCTTCCTTCTTGTATT
GCTTGTCTATCAAAGCCAGGAAAGTGGGGGATCACTGTAGTTAAATTTTTTTTTTTTTTAATTAGAGACAGAGTCTTGCCCTGTCGCCCA
AGCTGGAGTGCACTGGCGCAATCGTGGTACACTGCAGCCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCCTCAGCTTCCCAAGTAGTTG
GGAGTAGGTGCACACCACCATGCCCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCTGGTATCAAAATTACTGGCC
TCAAGCGATTCTCCTGCCTCGGCCTCCCAGATGTTGGGATTACTGGTGTGAGCCACCACGCCCAGCTCAAAAACAATTTTTTTAGGGGCA
CTTCTACAAATCATGAAAGGGGGATAAAAGCACTGACTTTAAAAAGCCATGTTTAAGATGCTATAAATGTTCTCCCCTTTTCATTGATTG
GAGAGTTGTAGAGGACCTTAGAGATCATTTTGTCTAACTCCCTCATCCCAAAGATAAACTGAGGCCTAGAGATCGTTCAGGGTGTTGTAA
CTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGG
TGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATC
GTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCC
TAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATG
CTGAGGCTTAGTCCAGTGTTCTCTCTCCCTTACCACTCCTCTTCCCCTTCCCTCTATAATGGCAGTACCCAGGGCCCGGTCCATAGACTA
CTATCGAGTGCTCCTATGTGCATCTTAGTACGTATCATTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTGGTAGCAACTGCCCTTGCT
AATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCC
TTTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCC
CATGGCACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATG
CCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCACCTAACACAGTGCCTTGCACACAAACAATAAATGATTGTTGAGTGAATAAG

>In-frame_ENST00000540147_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=192AA_start in transcript=25_stop in transcript=603
MRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATW

--------------------------------------------------------------
>In-frame_ENST00000584450_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4352nt_BP=440nt
GCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCGGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGC
GCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAGCACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCA
GCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGCCGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCG
GAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACC
TCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTC
CAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTT
GGAATATATATCGATACATTATGGTGCCGAGTGGTAACATGGGAGTGTTTGATCCAACAGAAATACACAATCGAGGGCAGCTGAAGTCAC
ACATGAAAGAAGCCATGATCAAGCTTGGTTTCCACTTGCTCTGCTTCTTCATGTATCTTTATAGTATGATCTTAGCTTTGATAAATGACT
GAAGCTGGAGAAGCCGTGGTTGAAGTCAGCCTACACTACAGTGCACAGTTGAGGAGCCAGAGACTTCTTAAATCATCCTTAGAACCGTGA
CCATAGCAGTATATATTTTCCTCTTGGAACAAAAAACTATTTTTGCTGTATTTTTACCATATAAAGTATTTAAAAAACATGAATTGAGTT
TCTGTAGATTTCTAGTTCTCAACTTTAGCCTGAACGCCAACACTTGAAGGTGTTTTTCATCCTCTGTATGTTGAAGGTGGTTATTTGTAT
GTAGGAACAGGACTGCCATCCCAGCTTTGCATGCCAAAGAAATAAAGAACACACTTTAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGG
TGCCCTTCAGGTCTACTGAAAAGTTAGAGTACAAAACAACACTGTTGATCTGGACAAAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGT
GACAACTTCATTTAATATGGTTTAAAGATTTATGAGACTGTCAGCTAAAAGTCTTTTCACAAGAATGTCAACAGAGAATGGCATCTCAAA
ATATATATATTTCTTTGCACAATTTGTGAAACCTTATAAGCCATTTTCCCCAGGTACAATGTAGTTCCTGCTGATAGAAAGGAAATATTT
TGTCAAGAGCTTTCATTTAAAAGCTACTACCTCCACAATCACCCCCAAACCCAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGT
ATTGCAGTTATTCCAATTGTATTTGATCTCCCTGATAACGTATTTTCATGGGTTTGGGTAGAAGATGCTAATCAGATTAGAAGCAGGAAT
AGTTATTTGCTGTCTGTGAAATTGAGCCTTTTGGTGCGCCACGTGGTGCCAGATCAACACTTCTATCCCTCTGCACTGACCACGTTGTGA
ACTGGGAGACCAAATGCAAGCCATTTCATGGACATAGCAATATACAACCAAACTCTGTTCCTTGGAGTTATATTGTAAACTCTTGCAGGT
GGGAGAGCAGTTCACCTCCTTAGCTCTGTTTGCCAGCTCTTACAGGGTAAAATAAACCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTT
TAATGTTGCTATCTTAAGCACTGGCATTTGGGCAAAACATGACTGTGTTCTGTGGGAGAATCCAAAGGCATTATTCACTCTAGTTGAGAT
AGAATTGGGTGGCTAAACAGGGTGTGTGGTACCCAAAAGATTAAATGTTACATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGA
AGCAAGGGAGCCACTAAGCCAAACTCCCTGTGCAGACAGACCATGTTTCAAGGCTGGAAGTAGTGCCCTGGCAACACACAAAAGGAACGG
TGAAATGGTAGGCAAAGTGAACTTGGCTCTGCTGGCCTCTTTGGGGTCACAGAAATTGCTCCTTGTGGTAATCTTATATTTCTGTCAGGC
ACAGGGCCAAGAAGCTGTGTAACAGACATTACTTTGCTTGCATCTCTTTTTCATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAAC
AGTCCCTTCACTCTGCCTTTCCTCCTAACTTCCTGTGCCTCTTCATGTTCTGCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTT
AAATCCTTGCAACTGAGAGATAAGCTACTTAAAGGCGGTAGAGATCTTTTTTTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAG
GCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCTTTCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGG
GATTACGGCTAGCTACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGAC
CTCAAACGATCTGCCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCTGGCCATGTAGATGACTTTTGACCAA
AATGTTTCACCTTCTCATTCAGATATTCTTAGTAACCAAAACAGTGACTCATGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTAC
ATCAGGCTTGCTGAGGCTAAGCAAATCAGAAAGGTGCCATGTTTATAACAGAGGTCAAAGCTCCTTACTTCTGAAACATTAGCTGTGGTT
AAAAACAAAAACTCTTCCTTCTTGTATTGCTTGTCTATCAAAGCCAGGAAAGTGGGGGATCACTGTAGTTAAATTTTTTTTTTTTTTAAT
TAGAGACAGAGTCTTGCCCTGTCGCCCAAGCTGGAGTGCACTGGCGCAATCGTGGTACACTGCAGCCTTGAACTCCTGGACTCAAGCAGT
CCTCCTGCCTCAGCTTCCCAAGTAGTTGGGAGTAGGTGCACACCACCATGCCCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCTATGTT
GCCTAGGCTGGTATCAAAATTACTGGCCTCAAGCGATTCTCCTGCCTCGGCCTCCCAGATGTTGGGATTACTGGTGTGAGCCACCACGCC
CAGCTCAAAAACAATTTTTTTAGGGGCACTTCTACAAATCATGAAAGGGGGATAAAAGCACTGACTTTAAAAAGCCATGTTTAAGATGCT
ATAAATGTTCTCCCCTTTTCATTGATTGGAGAGTTGTAGAGGACCTTAGAGATCATTTTGTCTAACTCCCTCATCCCAAAGATAAACTGA
GGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTG
AATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGG
AACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTG
TAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCA
GGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCTTAGTCCAGTGTTCTCTCTCCCTTACCACTCCTCTTCCCCTTCCCTCTATAATGG
CAGTACCCAGGGCCCGGTCCATAGACTACTATCGAGTGCTCCTATGTGCATCTTAGTACGTATCATTTTCCCTTGCCTTTTTCCTTCTAT
CCTTTCAGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCAT
CAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGC
TAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAG
ATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCACCTAACACAGTGCCTTGCACACA

>In-frame_ENST00000584450_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=239AA_start in transcript=2_stop in transcript=721
LRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATW

--------------------------------------------------------------
>In-frame_ENST00000584450_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=937nt_BP=440nt
GCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCGGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGC
GCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAGCACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCA
GCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGCCGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCG
GAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACC
TCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTC
CAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTT
GGAATATATATCGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAG
TTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTA
AGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACT
CTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCACCTAACACAGTGCCTTGC

>In-frame_ENST00000584450_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=190AA_start in transcript=2_stop in transcript=574
LRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATW

--------------------------------------------------------------
>In-frame_ENST00000584450_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4211nt_BP=440nt
GCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCGGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGC
GCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAGCACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCA
GCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGCCGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCG
GAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACC
TCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTC
CAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTT
GGAATATATATCGTATGATCTTAGCTTTGATAAATGACTGAAGCTGGAGAAGCCGTGGTTGAAGTCAGCCTACACTACAGTGCACAGTTG
AGGAGCCAGAGACTTCTTAAATCATCCTTAGAACCGTGACCATAGCAGTATATATTTTCCTCTTGGAACAAAAAACTATTTTTGCTGTAT
TTTTACCATATAAAGTATTTAAAAAACATGAATTGAGTTTCTGTAGATTTCTAGTTCTCAACTTTAGCCTGAACGCCAACACTTGAAGGT
GTTTTTCATCCTCTGTATGTTGAAGGTGGTTATTTGTATGTAGGAACAGGACTGCCATCCCAGCTTTGCATGCCAAAGAAATAAAGAACA
CACTTTAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAGGTCTACTGAAAAGTTAGAGTACAAAACAACACTGTTGATCT
GGACAAAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGTGACAACTTCATTTAATATGGTTTAAAGATTTATGAGACTGTCAGCTAAAAG
TCTTTTCACAAGAATGTCAACAGAGAATGGCATCTCAAAATATATATATTTCTTTGCACAATTTGTGAAACCTTATAAGCCATTTTCCCC
AGGTACAATGTAGTTCCTGCTGATAGAAAGGAAATATTTTGTCAAGAGCTTTCATTTAAAAGCTACTACCTCCACAATCACCCCCAAACC
CAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTATTCCAATTGTATTTGATCTCCCTGATAACGTATTTTCATGG
GTTTGGGTAGAAGATGCTAATCAGATTAGAAGCAGGAATAGTTATTTGCTGTCTGTGAAATTGAGCCTTTTGGTGCGCCACGTGGTGCCA
GATCAACACTTCTATCCCTCTGCACTGACCACGTTGTGAACTGGGAGACCAAATGCAAGCCATTTCATGGACATAGCAATATACAACCAA
ACTCTGTTCCTTGGAGTTATATTGTAAACTCTTGCAGGTGGGAGAGCAGTTCACCTCCTTAGCTCTGTTTGCCAGCTCTTACAGGGTAAA
ATAAACCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCTATCTTAAGCACTGGCATTTGGGCAAAACATGACTGTGTTCT
GTGGGAGAATCCAAAGGCATTATTCACTCTAGTTGAGATAGAATTGGGTGGCTAAACAGGGTGTGTGGTACCCAAAAGATTAAATGTTAC
ATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAGCCACTAAGCCAAACTCCCTGTGCAGACAGACCATGTTTCAA
GGCTGGAAGTAGTGCCCTGGCAACACACAAAAGGAACGGTGAAATGGTAGGCAAAGTGAACTTGGCTCTGCTGGCCTCTTTGGGGTCACA
GAAATTGCTCCTTGTGGTAATCTTATATTTCTGTCAGGCACAGGGCCAAGAAGCTGTGTAACAGACATTACTTTGCTTGCATCTCTTTTT
CATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCACTCTGCCTTTCCTCCTAACTTCCTGTGCCTCTTCATGTTCT
GCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTTAAATCCTTGCAACTGAGAGATAAGCTACTTAAAGGCGGTAGAGATCTTTTT
TTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCTTTCTGGG
TTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGCTAGCTACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGG
GTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGATCTGCCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAGGTGT
GAGCCACTGCGCCTGGCCATGTAGATGACTTTTGACCAAAATGTTTCACCTTCTCATTCAGATATTCTTAGTAACCAAAACAGTGACTCA
TGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTACATCAGGCTTGCTGAGGCTAAGCAAATCAGAAAGGTGCCATGTTTATAACAG
AGGTCAAAGCTCCTTACTTCTGAAACATTAGCTGTGGTTAAAAACAAAAACTCTTCCTTCTTGTATTGCTTGTCTATCAAAGCCAGGAAA
GTGGGGGATCACTGTAGTTAAATTTTTTTTTTTTTTAATTAGAGACAGAGTCTTGCCCTGTCGCCCAAGCTGGAGTGCACTGGCGCAATC
GTGGTACACTGCAGCCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCCTCAGCTTCCCAAGTAGTTGGGAGTAGGTGCACACCACCATGC
CCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCTGGTATCAAAATTACTGGCCTCAAGCGATTCTCCTGCCTCGGC
CTCCCAGATGTTGGGATTACTGGTGTGAGCCACCACGCCCAGCTCAAAAACAATTTTTTTAGGGGCACTTCTACAAATCATGAAAGGGGG
ATAAAAGCACTGACTTTAAAAAGCCATGTTTAAGATGCTATAAATGTTCTCCCCTTTTCATTGATTGGAGAGTTGTAGAGGACCTTAGAG
ATCATTTTGTCTAACTCCCTCATCCCAAAGATAAACTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGG
CCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAA
TGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAA
CATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTA
ACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCTTAGTCCAGTGTTCTC
TCTCCCTTACCACTCCTCTTCCCCTTCCCTCTATAATGGCAGTACCCAGGGCCCGGTCCATAGACTACTATCGAGTGCTCCTATGTGCAT
CTTAGTACGTATCATTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGA
AAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTAC
AGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATC
TGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTT

>In-frame_ENST00000584450_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=192AA_start in transcript=2_stop in transcript=580
LRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATW

--------------------------------------------------------------
>In-frame_ENST00000269571_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4296nt_BP=384nt
GGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAG
CACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGC
CGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCC
AGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACC
AATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGG
TTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGATACATTATGGTGCCGAGTGGTAACATGGGAGTGTTTGATCCA
ACAGAAATACACAATCGAGGGCAGCTGAAGTCACACATGAAAGAAGCCATGATCAAGCTTGGTTTCCACTTGCTCTGCTTCTTCATGTAT
CTTTATAGTATGATCTTAGCTTTGATAAATGACTGAAGCTGGAGAAGCCGTGGTTGAAGTCAGCCTACACTACAGTGCACAGTTGAGGAG
CCAGAGACTTCTTAAATCATCCTTAGAACCGTGACCATAGCAGTATATATTTTCCTCTTGGAACAAAAAACTATTTTTGCTGTATTTTTA
CCATATAAAGTATTTAAAAAACATGAATTGAGTTTCTGTAGATTTCTAGTTCTCAACTTTAGCCTGAACGCCAACACTTGAAGGTGTTTT
TCATCCTCTGTATGTTGAAGGTGGTTATTTGTATGTAGGAACAGGACTGCCATCCCAGCTTTGCATGCCAAAGAAATAAAGAACACACTT
TAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAGGTCTACTGAAAAGTTAGAGTACAAAACAACACTGTTGATCTGGACA
AAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGTGACAACTTCATTTAATATGGTTTAAAGATTTATGAGACTGTCAGCTAAAAGTCTTT
TCACAAGAATGTCAACAGAGAATGGCATCTCAAAATATATATATTTCTTTGCACAATTTGTGAAACCTTATAAGCCATTTTCCCCAGGTA
CAATGTAGTTCCTGCTGATAGAAAGGAAATATTTTGTCAAGAGCTTTCATTTAAAAGCTACTACCTCCACAATCACCCCCAAACCCAGAA
AATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTATTCCAATTGTATTTGATCTCCCTGATAACGTATTTTCATGGGTTTG
GGTAGAAGATGCTAATCAGATTAGAAGCAGGAATAGTTATTTGCTGTCTGTGAAATTGAGCCTTTTGGTGCGCCACGTGGTGCCAGATCA
ACACTTCTATCCCTCTGCACTGACCACGTTGTGAACTGGGAGACCAAATGCAAGCCATTTCATGGACATAGCAATATACAACCAAACTCT
GTTCCTTGGAGTTATATTGTAAACTCTTGCAGGTGGGAGAGCAGTTCACCTCCTTAGCTCTGTTTGCCAGCTCTTACAGGGTAAAATAAA
CCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCTATCTTAAGCACTGGCATTTGGGCAAAACATGACTGTGTTCTGTGGG
AGAATCCAAAGGCATTATTCACTCTAGTTGAGATAGAATTGGGTGGCTAAACAGGGTGTGTGGTACCCAAAAGATTAAATGTTACATGTC
CTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAGCCACTAAGCCAAACTCCCTGTGCAGACAGACCATGTTTCAAGGCTG
GAAGTAGTGCCCTGGCAACACACAAAAGGAACGGTGAAATGGTAGGCAAAGTGAACTTGGCTCTGCTGGCCTCTTTGGGGTCACAGAAAT
TGCTCCTTGTGGTAATCTTATATTTCTGTCAGGCACAGGGCCAAGAAGCTGTGTAACAGACATTACTTTGCTTGCATCTCTTTTTCATAC
CTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCACTCTGCCTTTCCTCCTAACTTCCTGTGCCTCTTCATGTTCTGCTCA
AGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTTAAATCCTTGCAACTGAGAGATAAGCTACTTAAAGGCGGTAGAGATCTTTTTTTTTT
TTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCTTTCTGGGTTCAA
GCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGCTAGCTACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTC
ACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGATCTGCCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAGGTGTGAGCC
ACTGCGCCTGGCCATGTAGATGACTTTTGACCAAAATGTTTCACCTTCTCATTCAGATATTCTTAGTAACCAAAACAGTGACTCATGCAG
TTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTACATCAGGCTTGCTGAGGCTAAGCAAATCAGAAAGGTGCCATGTTTATAACAGAGGTC
AAAGCTCCTTACTTCTGAAACATTAGCTGTGGTTAAAAACAAAAACTCTTCCTTCTTGTATTGCTTGTCTATCAAAGCCAGGAAAGTGGG
GGATCACTGTAGTTAAATTTTTTTTTTTTTTAATTAGAGACAGAGTCTTGCCCTGTCGCCCAAGCTGGAGTGCACTGGCGCAATCGTGGT
ACACTGCAGCCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCCTCAGCTTCCCAAGTAGTTGGGAGTAGGTGCACACCACCATGCCCAGC
GAATTTTTTGTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCTGGTATCAAAATTACTGGCCTCAAGCGATTCTCCTGCCTCGGCCTCCC
AGATGTTGGGATTACTGGTGTGAGCCACCACGCCCAGCTCAAAAACAATTTTTTTAGGGGCACTTCTACAAATCATGAAAGGGGGATAAA
AGCACTGACTTTAAAAAGCCATGTTTAAGATGCTATAAATGTTCTCCCCTTTTCATTGATTGGAGAGTTGTAGAGGACCTTAGAGATCAT
TTTGTCTAACTCCCTCATCCCAAAGATAAACTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAG
AGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTG
AGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCT
GAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGG
GAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCTTAGTCCAGTGTTCTCTCTCC
CTTACCACTCCTCTTCCCCTTCCCTCTATAATGGCAGTACCCAGGGCCCGGTCCATAGACTACTATCGAGTGCTCCTATGTGCATCTTAG
TACGTATCATTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAA
GAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAG
GACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTA
TTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTC

>In-frame_ENST00000269571_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=202AA_start in transcript=57_stop in transcript=665
MRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVV
QGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATWNIYRYIMVPSGNMGVFDPTEIHNRGQLKSHMKEAMIK

--------------------------------------------------------------
>In-frame_ENST00000269571_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=881nt_BP=384nt
GGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAG
CACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGC
CGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCC
AGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACC
AATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGG
TTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGA
AAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTAC
AGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATC
TGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTT

>In-frame_ENST00000269571_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=153AA_start in transcript=57_stop in transcript=518
MRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVV

--------------------------------------------------------------
>In-frame_ENST00000269571_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4155nt_BP=384nt
GGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAG
CACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGC
CGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCC
AGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACC
AATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATTGCACTGG
TTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGTATGATCTTAGCTTTGATAAATGACTGAAGCTGGAGAAGCCGT
GGTTGAAGTCAGCCTACACTACAGTGCACAGTTGAGGAGCCAGAGACTTCTTAAATCATCCTTAGAACCGTGACCATAGCAGTATATATT
TTCCTCTTGGAACAAAAAACTATTTTTGCTGTATTTTTACCATATAAAGTATTTAAAAAACATGAATTGAGTTTCTGTAGATTTCTAGTT
CTCAACTTTAGCCTGAACGCCAACACTTGAAGGTGTTTTTCATCCTCTGTATGTTGAAGGTGGTTATTTGTATGTAGGAACAGGACTGCC
ATCCCAGCTTTGCATGCCAAAGAAATAAAGAACACACTTTAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAGGTCTACT
GAAAAGTTAGAGTACAAAACAACACTGTTGATCTGGACAAAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGTGACAACTTCATTTAATA
TGGTTTAAAGATTTATGAGACTGTCAGCTAAAAGTCTTTTCACAAGAATGTCAACAGAGAATGGCATCTCAAAATATATATATTTCTTTG
CACAATTTGTGAAACCTTATAAGCCATTTTCCCCAGGTACAATGTAGTTCCTGCTGATAGAAAGGAAATATTTTGTCAAGAGCTTTCATT
TAAAAGCTACTACCTCCACAATCACCCCCAAACCCAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTATTCCAAT
TGTATTTGATCTCCCTGATAACGTATTTTCATGGGTTTGGGTAGAAGATGCTAATCAGATTAGAAGCAGGAATAGTTATTTGCTGTCTGT
GAAATTGAGCCTTTTGGTGCGCCACGTGGTGCCAGATCAACACTTCTATCCCTCTGCACTGACCACGTTGTGAACTGGGAGACCAAATGC
AAGCCATTTCATGGACATAGCAATATACAACCAAACTCTGTTCCTTGGAGTTATATTGTAAACTCTTGCAGGTGGGAGAGCAGTTCACCT
CCTTAGCTCTGTTTGCCAGCTCTTACAGGGTAAAATAAACCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCTATCTTAA
GCACTGGCATTTGGGCAAAACATGACTGTGTTCTGTGGGAGAATCCAAAGGCATTATTCACTCTAGTTGAGATAGAATTGGGTGGCTAAA
CAGGGTGTGTGGTACCCAAAAGATTAAATGTTACATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAGCCACTAA
GCCAAACTCCCTGTGCAGACAGACCATGTTTCAAGGCTGGAAGTAGTGCCCTGGCAACACACAAAAGGAACGGTGAAATGGTAGGCAAAG
TGAACTTGGCTCTGCTGGCCTCTTTGGGGTCACAGAAATTGCTCCTTGTGGTAATCTTATATTTCTGTCAGGCACAGGGCCAAGAAGCTG
TGTAACAGACATTACTTTGCTTGCATCTCTTTTTCATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCACTCTGCC
TTTCCTCCTAACTTCCTGTGCCTCTTCATGTTCTGCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTTAAATCCTTGCAACTGAG
AGATAAGCTACTTAAAGGCGGTAGAGATCTTTTTTTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTG
TGATCTCAGCTCACTGCAACCTCTGCTTTCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGCTAGCTACT
CCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGATCTGCCTG
CCTTGGTCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCTGGCCATGTAGATGACTTTTGACCAAAATGTTTCACCTTCTCA
TTCAGATATTCTTAGTAACCAAAACAGTGACTCATGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTACATCAGGCTTGCTGAGGC
TAAGCAAATCAGAAAGGTGCCATGTTTATAACAGAGGTCAAAGCTCCTTACTTCTGAAACATTAGCTGTGGTTAAAAACAAAAACTCTTC
CTTCTTGTATTGCTTGTCTATCAAAGCCAGGAAAGTGGGGGATCACTGTAGTTAAATTTTTTTTTTTTTTAATTAGAGACAGAGTCTTGC
CCTGTCGCCCAAGCTGGAGTGCACTGGCGCAATCGTGGTACACTGCAGCCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCCTCAGCTTC
CCAAGTAGTTGGGAGTAGGTGCACACCACCATGCCCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCTGGTATCAA
AATTACTGGCCTCAAGCGATTCTCCTGCCTCGGCCTCCCAGATGTTGGGATTACTGGTGTGAGCCACCACGCCCAGCTCAAAAACAATTT
TTTTAGGGGCACTTCTACAAATCATGAAAGGGGGATAAAAGCACTGACTTTAAAAAGCCATGTTTAAGATGCTATAAATGTTCTCCCCTT
TTCATTGATTGGAGAGTTGTAGAGGACCTTAGAGATCATTTTGTCTAACTCCCTCATCCCAAAGATAAACTGAGGCCTAGAGATCGTTCA
GGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAG
ATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAG
GCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGA
ATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGA
ACATCTGAATGCTGAGGCTTAGTCCAGTGTTCTCTCTCCCTTACCACTCCTCTTCCCCTTCCCTCTATAATGGCAGTACCCAGGGCCCGG
TCCATAGACTACTATCGAGTGCTCCTATGTGCATCTTAGTACGTATCATTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTGGTAGCAA
CTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCC
CCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATA
GTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAG
GGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCACCTAACACAGTGCCTTGCACACAAACAATAAATGATTGTT

>In-frame_ENST00000269571_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=155AA_start in transcript=57_stop in transcript=524
MRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVV

--------------------------------------------------------------
>In-frame_ENST00000578199_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4588nt_BP=676nt
GTCCACACAGTTTAAATTAAAGTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATA
GGGTTAAGGGAAGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGTCGCAATTGAAGTACCACCT
CCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCCAGCACAGAATTTGGCTTATGCCTAC
TCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTGGCAAAGCAAAGCTATATTCAAGACCAC
ATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCCAGGACAAACGCAGTGCAGCACAGAGACTC
AGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTGTTGTGGACATGCACAAAAGTGAGTGTGCACCGGCACAGA
CATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCT
GGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATT
ACTGCTCATGTCATTGCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGATACATTATGGTGCCGAGTGG
TAACATGGGAGTGTTTGATCCAACAGAAATACACAATCGAGGGCAGCTGAAGTCACACATGAAAGAAGCCATGATCAAGCTTGGTTTCCA
CTTGCTCTGCTTCTTCATGTATCTTTATAGTATGATCTTAGCTTTGATAAATGACTGAAGCTGGAGAAGCCGTGGTTGAAGTCAGCCTAC
ACTACAGTGCACAGTTGAGGAGCCAGAGACTTCTTAAATCATCCTTAGAACCGTGACCATAGCAGTATATATTTTCCTCTTGGAACAAAA
AACTATTTTTGCTGTATTTTTACCATATAAAGTATTTAAAAAACATGAATTGAGTTTCTGTAGATTTCTAGTTCTCAACTTTAGCCTGAA
CGCCAACACTTGAAGGTGTTTTTCATCCTCTGTATGTTGAAGGTGGTTATTTGTATGTAGGAACAGGACTGCCATCCCAGCTTTGCATGC
CAAAGAAATAAAGAACACACTTTAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAGGTCTACTGAAAAGTTAGAGTACAA
AACAACACTGTTGATCTGGACAAAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGTGACAACTTCATTTAATATGGTTTAAAGATTTATG
AGACTGTCAGCTAAAAGTCTTTTCACAAGAATGTCAACAGAGAATGGCATCTCAAAATATATATATTTCTTTGCACAATTTGTGAAACCT
TATAAGCCATTTTCCCCAGGTACAATGTAGTTCCTGCTGATAGAAAGGAAATATTTTGTCAAGAGCTTTCATTTAAAAGCTACTACCTCC
ACAATCACCCCCAAACCCAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTATTCCAATTGTATTTGATCTCCCTG
ATAACGTATTTTCATGGGTTTGGGTAGAAGATGCTAATCAGATTAGAAGCAGGAATAGTTATTTGCTGTCTGTGAAATTGAGCCTTTTGG
TGCGCCACGTGGTGCCAGATCAACACTTCTATCCCTCTGCACTGACCACGTTGTGAACTGGGAGACCAAATGCAAGCCATTTCATGGACA
TAGCAATATACAACCAAACTCTGTTCCTTGGAGTTATATTGTAAACTCTTGCAGGTGGGAGAGCAGTTCACCTCCTTAGCTCTGTTTGCC
AGCTCTTACAGGGTAAAATAAACCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCTATCTTAAGCACTGGCATTTGGGCA
AAACATGACTGTGTTCTGTGGGAGAATCCAAAGGCATTATTCACTCTAGTTGAGATAGAATTGGGTGGCTAAACAGGGTGTGTGGTACCC
AAAAGATTAAATGTTACATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAGCCACTAAGCCAAACTCCCTGTGCA
GACAGACCATGTTTCAAGGCTGGAAGTAGTGCCCTGGCAACACACAAAAGGAACGGTGAAATGGTAGGCAAAGTGAACTTGGCTCTGCTG
GCCTCTTTGGGGTCACAGAAATTGCTCCTTGTGGTAATCTTATATTTCTGTCAGGCACAGGGCCAAGAAGCTGTGTAACAGACATTACTT
TGCTTGCATCTCTTTTTCATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCACTCTGCCTTTCCTCCTAACTTCCT
GTGCCTCTTCATGTTCTGCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTTAAATCCTTGCAACTGAGAGATAAGCTACTTAAAG
GCGGTAGAGATCTTTTTTTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGC
AACCTCTGCTTTCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGCTAGCTACTCCTGGCTAATTTTTGTA
TTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGATCTGCCTGCCTTGGTCTCCCAAAGT
GCTGGGATTATAGGTGTGAGCCACTGCGCCTGGCCATGTAGATGACTTTTGACCAAAATGTTTCACCTTCTCATTCAGATATTCTTAGTA
ACCAAAACAGTGACTCATGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTACATCAGGCTTGCTGAGGCTAAGCAAATCAGAAAGG
TGCCATGTTTATAACAGAGGTCAAAGCTCCTTACTTCTGAAACATTAGCTGTGGTTAAAAACAAAAACTCTTCCTTCTTGTATTGCTTGT
CTATCAAAGCCAGGAAAGTGGGGGATCACTGTAGTTAAATTTTTTTTTTTTTTAATTAGAGACAGAGTCTTGCCCTGTCGCCCAAGCTGG
AGTGCACTGGCGCAATCGTGGTACACTGCAGCCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCCTCAGCTTCCCAAGTAGTTGGGAGTA
GGTGCACACCACCATGCCCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCTGGTATCAAAATTACTGGCCTCAAGC
GATTCTCCTGCCTCGGCCTCCCAGATGTTGGGATTACTGGTGTGAGCCACCACGCCCAGCTCAAAAACAATTTTTTTAGGGGCACTTCTA
CAAATCATGAAAGGGGGATAAAAGCACTGACTTTAAAAAGCCATGTTTAAGATGCTATAAATGTTCTCCCCTTTTCATTGATTGGAGAGT
TGTAGAGGACCTTAGAGATCATTTTGTCTAACTCCCTCATCCCAAAGATAAACTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGA
ACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGT
AACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAG
GGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGA
TCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGG
CTTAGTCCAGTGTTCTCTCTCCCTTACCACTCCTCTTCCCCTTCCCTCTATAATGGCAGTACCCAGGGCCCGGTCCATAGACTACTATCG
AGTGCTCCTATGTGCATCTTAGTACGTATCATTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTGGTAGCAACTGCCCTTGCTAATCAC
CGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCA
TGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGC
ACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATT

>In-frame_ENST00000578199_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=138AA_start in transcript=541_stop in transcript=957
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATWNIYRYIMVPSG

--------------------------------------------------------------
>In-frame_ENST00000578199_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=1173nt_BP=676nt
GTCCACACAGTTTAAATTAAAGTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATA
GGGTTAAGGGAAGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGTCGCAATTGAAGTACCACCT
CCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCCAGCACAGAATTTGGCTTATGCCTAC
TCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTGGCAAAGCAAAGCTATATTCAAGACCAC
ATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCCAGGACAAACGCAGTGCAGCACAGAGACTC
AGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTGTTGTGGACATGCACAAAAGTGAGTGTGCACCGGCACAGA
CATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCT
GGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATT
ACTGCTCATGTCATTGCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGTGGTAGCAACTGCCCTTGCTA
ATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCT
TTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCC
ATGGCACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGC
CCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCACCTAACACAGTGCCTTGCACACAAACAATAAATGATTGTTGAGTGAATAAGT

>In-frame_ENST00000578199_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=98AA_start in transcript=498_stop in transcript=794
MLWTCTKVSVHRHRHEAAAPCQSRDPPGHAPPPLPGLPGGAGKPGTHLPAHQCQPVLPAVGNSRIDWPYHCHCITAHVIALVHLPSQLTC

--------------------------------------------------------------
>In-frame_ENST00000578199_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4447nt_BP=676nt
GTCCACACAGTTTAAATTAAAGTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATA
GGGTTAAGGGAAGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGTCGCAATTGAAGTACCACCT
CCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCCAGCACAGAATTTGGCTTATGCCTAC
TCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTGGCAAAGCAAAGCTATATTCAAGACCAC
ATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCCAGGACAAACGCAGTGCAGCACAGAGACTC
AGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTGTTGTGGACATGCACAAAAGTGAGTGTGCACCGGCACAGA
CATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCT
GGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATT
ACTGCTCATGTCATTGCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGTATGATCTTAGCTTTGATAAA
TGACTGAAGCTGGAGAAGCCGTGGTTGAAGTCAGCCTACACTACAGTGCACAGTTGAGGAGCCAGAGACTTCTTAAATCATCCTTAGAAC
CGTGACCATAGCAGTATATATTTTCCTCTTGGAACAAAAAACTATTTTTGCTGTATTTTTACCATATAAAGTATTTAAAAAACATGAATT
GAGTTTCTGTAGATTTCTAGTTCTCAACTTTAGCCTGAACGCCAACACTTGAAGGTGTTTTTCATCCTCTGTATGTTGAAGGTGGTTATT
TGTATGTAGGAACAGGACTGCCATCCCAGCTTTGCATGCCAAAGAAATAAAGAACACACTTTAAAGGGCAAACTGAAGAGATGAGCGAGC
AAAGGTGCCCTTCAGGTCTACTGAAAAGTTAGAGTACAAAACAACACTGTTGATCTGGACAAAAGAAGAAAAATTACCCTTTTTGCTTGT
GTTGTGACAACTTCATTTAATATGGTTTAAAGATTTATGAGACTGTCAGCTAAAAGTCTTTTCACAAGAATGTCAACAGAGAATGGCATC
TCAAAATATATATATTTCTTTGCACAATTTGTGAAACCTTATAAGCCATTTTCCCCAGGTACAATGTAGTTCCTGCTGATAGAAAGGAAA
TATTTTGTCAAGAGCTTTCATTTAAAAGCTACTACCTCCACAATCACCCCCAAACCCAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTT
TTCGTATTGCAGTTATTCCAATTGTATTTGATCTCCCTGATAACGTATTTTCATGGGTTTGGGTAGAAGATGCTAATCAGATTAGAAGCA
GGAATAGTTATTTGCTGTCTGTGAAATTGAGCCTTTTGGTGCGCCACGTGGTGCCAGATCAACACTTCTATCCCTCTGCACTGACCACGT
TGTGAACTGGGAGACCAAATGCAAGCCATTTCATGGACATAGCAATATACAACCAAACTCTGTTCCTTGGAGTTATATTGTAAACTCTTG
CAGGTGGGAGAGCAGTTCACCTCCTTAGCTCTGTTTGCCAGCTCTTACAGGGTAAAATAAACCTGGCAATTTATCCTCAGTCCTAGTTTG
TGGTTTAATGTTGCTATCTTAAGCACTGGCATTTGGGCAAAACATGACTGTGTTCTGTGGGAGAATCCAAAGGCATTATTCACTCTAGTT
GAGATAGAATTGGGTGGCTAAACAGGGTGTGTGGTACCCAAAAGATTAAATGTTACATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTG
GCAGAAGCAAGGGAGCCACTAAGCCAAACTCCCTGTGCAGACAGACCATGTTTCAAGGCTGGAAGTAGTGCCCTGGCAACACACAAAAGG
AACGGTGAAATGGTAGGCAAAGTGAACTTGGCTCTGCTGGCCTCTTTGGGGTCACAGAAATTGCTCCTTGTGGTAATCTTATATTTCTGT
CAGGCACAGGGCCAAGAAGCTGTGTAACAGACATTACTTTGCTTGCATCTCTTTTTCATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAG
AAAACAGTCCCTTCACTCTGCCTTTCCTCCTAACTTCCTGTGCCTCTTCATGTTCTGCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAG
AACTTAAATCCTTGCAACTGAGAGATAAGCTACTTAAAGGCGGTAGAGATCTTTTTTTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTG
CCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCTTTCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTA
GCTGGGATTACGGCTAGCTACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTC
CTGACCTCAAACGATCTGCCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCTGGCCATGTAGATGACTTTTG
ACCAAAATGTTTCACCTTCTCATTCAGATATTCTTAGTAACCAAAACAGTGACTCATGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTAC
AGTACATCAGGCTTGCTGAGGCTAAGCAAATCAGAAAGGTGCCATGTTTATAACAGAGGTCAAAGCTCCTTACTTCTGAAACATTAGCTG
TGGTTAAAAACAAAAACTCTTCCTTCTTGTATTGCTTGTCTATCAAAGCCAGGAAAGTGGGGGATCACTGTAGTTAAATTTTTTTTTTTT
TTAATTAGAGACAGAGTCTTGCCCTGTCGCCCAAGCTGGAGTGCACTGGCGCAATCGTGGTACACTGCAGCCTTGAACTCCTGGACTCAA
GCAGTCCTCCTGCCTCAGCTTCCCAAGTAGTTGGGAGTAGGTGCACACCACCATGCCCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCT
ATGTTGCCTAGGCTGGTATCAAAATTACTGGCCTCAAGCGATTCTCCTGCCTCGGCCTCCCAGATGTTGGGATTACTGGTGTGAGCCACC
ACGCCCAGCTCAAAAACAATTTTTTTAGGGGCACTTCTACAAATCATGAAAGGGGGATAAAAGCACTGACTTTAAAAAGCCATGTTTAAG
ATGCTATAAATGTTCTCCCCTTTTCATTGATTGGAGAGTTGTAGAGGACCTTAGAGATCATTTTGTCTAACTCCCTCATCCCAAAGATAA
ACTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAAC
ATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAA
CTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGG
TGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATC
GTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCTTAGTCCAGTGTTCTCTCTCCCTTACCACTCCTCTTCCCCTTCCCTCTAT
AATGGCAGTACCCAGGGCCCGGTCCATAGACTACTATCGAGTGCTCCTATGTGCATCTTAGTACGTATCATTTTCCCTTGCCTTTTTCCT
TCTATCCTTTCAGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAG
TTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTA
AGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACT
CTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCACCTAACACAGTGCCTTGC

>In-frame_ENST00000578199_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=104AA_start in transcript=498_stop in transcript=812
MLWTCTKVSVHRHRHEAAAPCQSRDPPGHAPPPLPGLPGGAGKPGTHLPAHQCQPVLPAVGNSRIDWPYHCHCITAHVIALVHLPSQLTC

--------------------------------------------------------------
>In-frame_ENST00000540042_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4213nt_BP=301nt
GAATGCACAGGGTGGGCCTAGTCAGAAGAAGCCTTTCCCCTGAAATCCCTCTACTTCCCAAGCACGCAAGCTTTCTCCTGCTGTTAAACC
TGCAGTGTGCAAGGGACATGGGCGGAGGGGTCCTTCAGTCAGGCTTCTCCCTGTCTGAGTGTGCACCGGCACAGACATGAAGCTGCGGCT
CCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCT
GCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATT
GCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGATACATTATGGTGCCGAGTGGTAACATGGGAGTGTT
TGATCCAACAGAAATACACAATCGAGGGCAGCTGAAGTCACACATGAAAGAAGCCATGATCAAGCTTGGTTTCCACTTGCTCTGCTTCTT
CATGTATCTTTATAGTATGATCTTAGCTTTGATAAATGACTGAAGCTGGAGAAGCCGTGGTTGAAGTCAGCCTACACTACAGTGCACAGT
TGAGGAGCCAGAGACTTCTTAAATCATCCTTAGAACCGTGACCATAGCAGTATATATTTTCCTCTTGGAACAAAAAACTATTTTTGCTGT
ATTTTTACCATATAAAGTATTTAAAAAACATGAATTGAGTTTCTGTAGATTTCTAGTTCTCAACTTTAGCCTGAACGCCAACACTTGAAG
GTGTTTTTCATCCTCTGTATGTTGAAGGTGGTTATTTGTATGTAGGAACAGGACTGCCATCCCAGCTTTGCATGCCAAAGAAATAAAGAA
CACACTTTAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAGGTCTACTGAAAAGTTAGAGTACAAAACAACACTGTTGAT
CTGGACAAAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGTGACAACTTCATTTAATATGGTTTAAAGATTTATGAGACTGTCAGCTAAA
AGTCTTTTCACAAGAATGTCAACAGAGAATGGCATCTCAAAATATATATATTTCTTTGCACAATTTGTGAAACCTTATAAGCCATTTTCC
CCAGGTACAATGTAGTTCCTGCTGATAGAAAGGAAATATTTTGTCAAGAGCTTTCATTTAAAAGCTACTACCTCCACAATCACCCCCAAA
CCCAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTATTCCAATTGTATTTGATCTCCCTGATAACGTATTTTCAT
GGGTTTGGGTAGAAGATGCTAATCAGATTAGAAGCAGGAATAGTTATTTGCTGTCTGTGAAATTGAGCCTTTTGGTGCGCCACGTGGTGC
CAGATCAACACTTCTATCCCTCTGCACTGACCACGTTGTGAACTGGGAGACCAAATGCAAGCCATTTCATGGACATAGCAATATACAACC
AAACTCTGTTCCTTGGAGTTATATTGTAAACTCTTGCAGGTGGGAGAGCAGTTCACCTCCTTAGCTCTGTTTGCCAGCTCTTACAGGGTA
AAATAAACCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCTATCTTAAGCACTGGCATTTGGGCAAAACATGACTGTGTT
CTGTGGGAGAATCCAAAGGCATTATTCACTCTAGTTGAGATAGAATTGGGTGGCTAAACAGGGTGTGTGGTACCCAAAAGATTAAATGTT
ACATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAGCCACTAAGCCAAACTCCCTGTGCAGACAGACCATGTTTC
AAGGCTGGAAGTAGTGCCCTGGCAACACACAAAAGGAACGGTGAAATGGTAGGCAAAGTGAACTTGGCTCTGCTGGCCTCTTTGGGGTCA
CAGAAATTGCTCCTTGTGGTAATCTTATATTTCTGTCAGGCACAGGGCCAAGAAGCTGTGTAACAGACATTACTTTGCTTGCATCTCTTT
TTCATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCACTCTGCCTTTCCTCCTAACTTCCTGTGCCTCTTCATGTT
CTGCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTTAAATCCTTGCAACTGAGAGATAAGCTACTTAAAGGCGGTAGAGATCTTT
TTTTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCTTTCTG
GGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGCTAGCTACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATG
GGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGATCTGCCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAGGT
GTGAGCCACTGCGCCTGGCCATGTAGATGACTTTTGACCAAAATGTTTCACCTTCTCATTCAGATATTCTTAGTAACCAAAACAGTGACT
CATGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTACATCAGGCTTGCTGAGGCTAAGCAAATCAGAAAGGTGCCATGTTTATAAC
AGAGGTCAAAGCTCCTTACTTCTGAAACATTAGCTGTGGTTAAAAACAAAAACTCTTCCTTCTTGTATTGCTTGTCTATCAAAGCCAGGA
AAGTGGGGGATCACTGTAGTTAAATTTTTTTTTTTTTTAATTAGAGACAGAGTCTTGCCCTGTCGCCCAAGCTGGAGTGCACTGGCGCAA
TCGTGGTACACTGCAGCCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCCTCAGCTTCCCAAGTAGTTGGGAGTAGGTGCACACCACCAT
GCCCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCTGGTATCAAAATTACTGGCCTCAAGCGATTCTCCTGCCTCG
GCCTCCCAGATGTTGGGATTACTGGTGTGAGCCACCACGCCCAGCTCAAAAACAATTTTTTTAGGGGCACTTCTACAAATCATGAAAGGG
GGATAAAAGCACTGACTTTAAAAAGCCATGTTTAAGATGCTATAAATGTTCTCCCCTTTTCATTGATTGGAGAGTTGTAGAGGACCTTAG
AGATCATTTTGTCTAACTCCCTCATCCCAAAGATAAACTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGA
GGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTG
AATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGG
AACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTG
TAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCTTAGTCCAGTGTTC
TCTCTCCCTTACCACTCCTCTTCCCCTTCCCTCTATAATGGCAGTACCCAGGGCCCGGTCCATAGACTACTATCGAGTGCTCCTATGTGC
ATCTTAGTACGTATCATTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGA
GAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACT
ACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTA
TCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTC

>In-frame_ENST00000540042_ENST00000465271_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=138AA_start in transcript=166_stop in transcript=582
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATWNIYRYIMVPSG

--------------------------------------------------------------
>In-frame_ENST00000540042_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=798nt_BP=301nt
GAATGCACAGGGTGGGCCTAGTCAGAAGAAGCCTTTCCCCTGAAATCCCTCTACTTCCCAAGCACGCAAGCTTTCTCCTGCTGTTAAACC
TGCAGTGTGCAAGGGACATGGGCGGAGGGGTCCTTCAGTCAGGCTTCTCCCTGTCTGAGTGTGCACCGGCACAGACATGAAGCTGCGGCT
CCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCT
GCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATT
GCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGTGGTAGCAACTGCCCTTGCTAATCACCGTAACCTCG
GCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAGCAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCAC
AGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCTTCCTATAGTAGTATCTCCCATGGCACTTACCACA
TTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTTCCTGGAGGGCAGAATATGCCCATTCATATTTGTA

>In-frame_ENST00000540042_ENST00000366858_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=91AA_start in transcript=144_stop in transcript=419
MSVHRHRHEAAAPCQSRDPPGHAPPPLPGLPGGAGKPGTHLPAHQCQPVLPAVGNSRIDWPYHCHCITAHVIALVHLPSQLTCCHLEYIS

--------------------------------------------------------------
>In-frame_ENST00000540042_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(transcript)=4072nt_BP=301nt
GAATGCACAGGGTGGGCCTAGTCAGAAGAAGCCTTTCCCCTGAAATCCCTCTACTTCCCAAGCACGCAAGCTTTCTCCTGCTGTTAAACC
TGCAGTGTGCAAGGGACATGGGCGGAGGGGTCCTTCAGTCAGGCTTCTCCCTGTCTGAGTGTGCACCGGCACAGACATGAAGCTGCGGCT
CCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCT
GCCCACCAATGCCAGCCTGTCCTTCCTGCAGTGGGTAATTCCAGAATTGATTGGCCATACCATTGTCACTGTATTACTGCTCATGTCATT
GCACTGGTTCATCTTCCTTCTCAACTTACCTGTTGCCACTTGGAATATATATCGTATGATCTTAGCTTTGATAAATGACTGAAGCTGGAG
AAGCCGTGGTTGAAGTCAGCCTACACTACAGTGCACAGTTGAGGAGCCAGAGACTTCTTAAATCATCCTTAGAACCGTGACCATAGCAGT
ATATATTTTCCTCTTGGAACAAAAAACTATTTTTGCTGTATTTTTACCATATAAAGTATTTAAAAAACATGAATTGAGTTTCTGTAGATT
TCTAGTTCTCAACTTTAGCCTGAACGCCAACACTTGAAGGTGTTTTTCATCCTCTGTATGTTGAAGGTGGTTATTTGTATGTAGGAACAG
GACTGCCATCCCAGCTTTGCATGCCAAAGAAATAAAGAACACACTTTAAAGGGCAAACTGAAGAGATGAGCGAGCAAAGGTGCCCTTCAG
GTCTACTGAAAAGTTAGAGTACAAAACAACACTGTTGATCTGGACAAAAGAAGAAAAATTACCCTTTTTGCTTGTGTTGTGACAACTTCA
TTTAATATGGTTTAAAGATTTATGAGACTGTCAGCTAAAAGTCTTTTCACAAGAATGTCAACAGAGAATGGCATCTCAAAATATATATAT
TTCTTTGCACAATTTGTGAAACCTTATAAGCCATTTTCCCCAGGTACAATGTAGTTCCTGCTGATAGAAAGGAAATATTTTGTCAAGAGC
TTTCATTTAAAAGCTACTACCTCCACAATCACCCCCAAACCCAGAAAATCCCCACTGGCTCTTGCCAGTCTGGTTTTCGTATTGCAGTTA
TTCCAATTGTATTTGATCTCCCTGATAACGTATTTTCATGGGTTTGGGTAGAAGATGCTAATCAGATTAGAAGCAGGAATAGTTATTTGC
TGTCTGTGAAATTGAGCCTTTTGGTGCGCCACGTGGTGCCAGATCAACACTTCTATCCCTCTGCACTGACCACGTTGTGAACTGGGAGAC
CAAATGCAAGCCATTTCATGGACATAGCAATATACAACCAAACTCTGTTCCTTGGAGTTATATTGTAAACTCTTGCAGGTGGGAGAGCAG
TTCACCTCCTTAGCTCTGTTTGCCAGCTCTTACAGGGTAAAATAAACCTGGCAATTTATCCTCAGTCCTAGTTTGTGGTTTAATGTTGCT
ATCTTAAGCACTGGCATTTGGGCAAAACATGACTGTGTTCTGTGGGAGAATCCAAAGGCATTATTCACTCTAGTTGAGATAGAATTGGGT
GGCTAAACAGGGTGTGTGGTACCCAAAAGATTAAATGTTACATGTCCTTTTAGTCCTTGACCAGGTCTAGCCTTGGCAGAAGCAAGGGAG
CCACTAAGCCAAACTCCCTGTGCAGACAGACCATGTTTCAAGGCTGGAAGTAGTGCCCTGGCAACACACAAAAGGAACGGTGAAATGGTA
GGCAAAGTGAACTTGGCTCTGCTGGCCTCTTTGGGGTCACAGAAATTGCTCCTTGTGGTAATCTTATATTTCTGTCAGGCACAGGGCCAA
GAAGCTGTGTAACAGACATTACTTTGCTTGCATCTCTTTTTCATACCTTTTCCCTCTGAGGCAGCTTTTGCTTAGAAAACAGTCCCTTCA
CTCTGCCTTTCCTCCTAACTTCCTGTGCCTCTTCATGTTCTGCTCAAGCTTTTTAAAGCAACGAAGCTGTTGGAGAACTTAAATCCTTGC
AACTGAGAGATAAGCTACTTAAAGGCGGTAGAGATCTTTTTTTTTTTTTTTTTGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGAGTGC
AGTGGTGTGATCTCAGCTCACTGCAACCTCTGCTTTCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACGGCT
AGCTACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGAT
CTGCCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCTGGCCATGTAGATGACTTTTGACCAAAATGTTTCAC
CTTCTCATTCAGATATTCTTAGTAACCAAAACAGTGACTCATGCAGTTGAGAGAGCCTTTGGGCTGTCAGTTTACAGTACATCAGGCTTG
CTGAGGCTAAGCAAATCAGAAAGGTGCCATGTTTATAACAGAGGTCAAAGCTCCTTACTTCTGAAACATTAGCTGTGGTTAAAAACAAAA
ACTCTTCCTTCTTGTATTGCTTGTCTATCAAAGCCAGGAAAGTGGGGGATCACTGTAGTTAAATTTTTTTTTTTTTTAATTAGAGACAGA
GTCTTGCCCTGTCGCCCAAGCTGGAGTGCACTGGCGCAATCGTGGTACACTGCAGCCTTGAACTCCTGGACTCAAGCAGTCCTCCTGCCT
CAGCTTCCCAAGTAGTTGGGAGTAGGTGCACACCACCATGCCCAGCGAATTTTTTGTAGAGACAGAGGTCTTGCTATGTTGCCTAGGCTG
GTATCAAAATTACTGGCCTCAAGCGATTCTCCTGCCTCGGCCTCCCAGATGTTGGGATTACTGGTGTGAGCCACCACGCCCAGCTCAAAA
ACAATTTTTTTAGGGGCACTTCTACAAATCATGAAAGGGGGATAAAAGCACTGACTTTAAAAAGCCATGTTTAAGATGCTATAAATGTTC
TCCCCTTTTCATTGATTGGAGAGTTGTAGAGGACCTTAGAGATCATTTTGTCTAACTCCCTCATCCCAAAGATAAACTGAGGCCTAGAGA
TCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGG
CCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAA
TGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAA
CATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTAACTGGGAACATCTGAATGCTGAGGCCTAGAGATCGTTCAGGGTGTTGTA
ACTGGGAACATCTGAATGCTGAGGCTTAGTCCAGTGTTCTCTCTCCCTTACCACTCCTCTTCCCCTTCCCTCTATAATGGCAGTACCCAG
GGCCCGGTCCATAGACTACTATCGAGTGCTCCTATGTGCATCTTAGTACGTATCATTTTCCCTTGCCTTTTTCCTTCTATCCTTTCAGTG
GTAGCAACTGCCCTTGCTAATCACCGTAACCTCGGCTGAGAAAGAAGAGGAAGCGAAATCCAAGATGCAGCTCAGTTCATCAAAGCCTAG
CAGGTCCCCTCAGCTGCCTTTTCATGCCTGCCACAGACTACAGTAGGACAAAACCTGACCTGGTCTTTGAAGTTAAGAGCTAAGAAAGCT
TCCTATAGTAGTATCTCCCATGGCACTTACCACATTCTATCTGGTATTACAGTTATTTGTATGCAATTAATCACTCTTAGATTGTATGTT
CCTGGAGGGCAGAATATGCCCATTCATATTTGTATCTTCTTCCTTCTGCTCTTGGCACCTAACACAGTGCCTTGCACACAAACAATAAAT

>In-frame_ENST00000540042_ENST00000366857_TCGA-D1-A3JP-01A_ERBB2_chr17_37863394_+_CNIH4_chr1_224553581_length(amino acids)=97AA_start in transcript=144_stop in transcript=437
MSVHRHRHEAAAPCQSRDPPGHAPPPLPGLPGGAGKPGTHLPAHQCQPVLPAVGNSRIDWPYHCHCITAHVIALVHLPSQLTCCHLEYIS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ERBB2-CNIH4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneERBB2chr17:37863394chr1:224553581ENST00000269571+2271195_119775.01256.0PIK3C2B
HgeneERBB2chr17:37863394chr1:224553581ENST00000541774+2271195_119760.01241.0PIK3C2B


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ERBB2-CNIH4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneERBB2P04626DB06366PertuzumabInhibitorBiotechApproved
HgeneERBB2P04626DB06366PertuzumabInhibitorBiotechApproved
HgeneERBB2P04626DB06366PertuzumabInhibitorBiotechApproved
HgeneERBB2P04626DB06366PertuzumabInhibitorBiotechApproved
HgeneERBB2P04626DB06366PertuzumabInhibitorBiotechApproved
HgeneERBB2P04626DB08916AfatinibInhibitorSmall moleculeApproved
HgeneERBB2P04626DB08916AfatinibInhibitorSmall moleculeApproved
HgeneERBB2P04626DB08916AfatinibInhibitorSmall moleculeApproved
HgeneERBB2P04626DB08916AfatinibInhibitorSmall moleculeApproved
HgeneERBB2P04626DB08916AfatinibInhibitorSmall moleculeApproved
HgeneERBB2P04626DB00072TrastuzumabAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB00072TrastuzumabAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB00072TrastuzumabAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB00072TrastuzumabAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB00072TrastuzumabAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB01259LapatinibAntagonistSmall moleculeApproved|Investigational
HgeneERBB2P04626DB01259LapatinibAntagonistSmall moleculeApproved|Investigational
HgeneERBB2P04626DB01259LapatinibAntagonistSmall moleculeApproved|Investigational
HgeneERBB2P04626DB01259LapatinibAntagonistSmall moleculeApproved|Investigational
HgeneERBB2P04626DB01259LapatinibAntagonistSmall moleculeApproved|Investigational
HgeneERBB2P04626DB05773Trastuzumab emtansineAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB05773Trastuzumab emtansineAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB05773Trastuzumab emtansineAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB05773Trastuzumab emtansineAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB05773Trastuzumab emtansineAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB11652TucatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB11652TucatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB11652TucatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB11652TucatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB11652TucatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB15035ZanubrutinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB15035ZanubrutinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB15035ZanubrutinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB15035ZanubrutinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB15035ZanubrutinibInhibitorSmall moleculeApproved|Investigational

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Related Diseases for ERBB2-CNIH4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneERBB2C0006142Malignant neoplasm of breast40CGI;CTD_human
HgeneERBB2C0678222Breast Carcinoma40CGI;CTD_human
HgeneERBB2C1257931Mammary Neoplasms, Human40CTD_human
HgeneERBB2C1458155Mammary Neoplasms40CTD_human
HgeneERBB2C4704874Mammary Carcinoma, Human40CTD_human
HgeneERBB2C1140680Malignant neoplasm of ovary4CGI;CTD_human;UNIPROT
HgeneERBB2C0024623Malignant neoplasm of stomach3CGI;CTD_human
HgeneERBB2C0033578Prostatic Neoplasms3CTD_human
HgeneERBB2C0038356Stomach Neoplasms3CGI;CTD_human
HgeneERBB2C0235874Disease Exacerbation3CTD_human
HgeneERBB2C0376358Malignant neoplasm of prostate3CTD_human
HgeneERBB2C1708349Hereditary Diffuse Gastric Cancer3CTD_human
HgeneERBB2C0001418Adenocarcinoma2CTD_human
HgeneERBB2C0024668Mammary Neoplasms, Experimental2CTD_human
HgeneERBB2C0205641Adenocarcinoma, Basal Cell2CTD_human
HgeneERBB2C0205642Adenocarcinoma, Oxyphilic2CTD_human
HgeneERBB2C0205643Carcinoma, Cribriform2CTD_human
HgeneERBB2C0205644Carcinoma, Granular Cell2CTD_human
HgeneERBB2C0205645Adenocarcinoma, Tubular2CTD_human
HgeneERBB2C0699791Stomach Carcinoma2CGI;UNIPROT
HgeneERBB2C0919267ovarian neoplasm2CGI;CTD_human
HgeneERBB2C0007102Malignant tumor of colon1CTD_human
HgeneERBB2C0007134Renal Cell Carcinoma1CTD_human
HgeneERBB2C0009375Colonic Neoplasms1CTD_human
HgeneERBB2C0013930Embolism, Tumor1CTD_human
HgeneERBB2C0014859Esophageal Neoplasms1CTD_human
HgeneERBB2C0016978gallbladder neoplasm1CTD_human
HgeneERBB2C0017185Gastrointestinal Neoplasms1CTD_human
HgeneERBB2C0021367Mammary Ductal Carcinoma1CTD_human
HgeneERBB2C0024121Lung Neoplasms1CTD_human
HgeneERBB2C0024232Lymphatic Metastasis1CTD_human
HgeneERBB2C0024667Animal Mammary Neoplasms1CTD_human
HgeneERBB2C0025149Medulloblastoma1CTD_human
HgeneERBB2C0027627Neoplasm Metastasis1CTD_human
HgeneERBB2C0027643Neoplasm Recurrence, Local1CTD_human
HgeneERBB2C0027659Neoplasms, Experimental1CTD_human
HgeneERBB2C0030354Papilloma1CTD_human
HgeneERBB2C0153452Malignant neoplasm of gallbladder1CTD_human
HgeneERBB2C0205833Medullomyoblastoma1CTD_human
HgeneERBB2C0205874Papilloma, Squamous Cell1CTD_human
HgeneERBB2C0205875Papillomatosis1CTD_human
HgeneERBB2C0206698Cholangiocarcinoma1CTD_human
HgeneERBB2C0242379Malignant neoplasm of lung1CTD_human
HgeneERBB2C0278510Childhood Medulloblastoma1CTD_human
HgeneERBB2C0278876Adult Medulloblastoma1CTD_human
HgeneERBB2C0279702Conventional (Clear Cell) Renal Cell Carcinoma1CTD_human
HgeneERBB2C0345905Intrahepatic Cholangiocarcinoma1CTD_human
HgeneERBB2C0546837Malignant neoplasm of esophagus1CTD_human
HgeneERBB2C0596263Carcinogenesis1CTD_human
HgeneERBB2C0684249Carcinoma of lung1UNIPROT
HgeneERBB2C0685938Malignant neoplasm of gastrointestinal tract1CTD_human
HgeneERBB2C0751291Desmoplastic Medulloblastoma1CTD_human
HgeneERBB2C1134719Invasive Ductal Breast Carcinoma1CTD_human
HgeneERBB2C1257925Mammary Carcinoma, Animal1CTD_human
HgeneERBB2C1266042Chromophobe Renal Cell Carcinoma1CTD_human
HgeneERBB2C1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
HgeneERBB2C1266044Collecting Duct Carcinoma of the Kidney1CTD_human
HgeneERBB2C1275668Melanotic medulloblastoma1CTD_human
HgeneERBB2C1306837Papillary Renal Cell Carcinoma1CTD_human
HgeneERBB2C1368275Pigmented Basal Cell Carcinoma1CTD_human
HgeneERBB2C2750850GLIOMA SUSCEPTIBILITY 11UNIPROT
HgeneERBB2C2931822Nasopharyngeal carcinoma1CTD_human
HgeneERBB2C3805278Extrahepatic Cholangiocarcinoma1CTD_human
HgeneERBB2C4721610Carcinoma, Ovarian Epithelial1CTD_human
HgeneERBB2C4721806Carcinoma, Basal Cell1CTD_human