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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ERBB2-EIF1 (FusionGDB2 ID:27112)

Fusion Gene Summary for ERBB2-EIF1

check button Fusion gene summary
Fusion gene informationFusion gene name: ERBB2-EIF1
Fusion gene ID: 27112
HgeneTgene
Gene symbol

ERBB2

EIF1

Gene ID

2064

10209

Gene nameerb-b2 receptor tyrosine kinase 2eukaryotic translation initiation factor 1
SynonymsCD340|HER-2|HER-2/neu|HER2|MLN 19|NEU|NGL|TKR1A121|EIF-1|EIF1A|ISO1|SUI1
Cytomap

17q12

17q21.2

Type of geneprotein-codingprotein-coding
Descriptionreceptor tyrosine-protein kinase erbB-2c-erb B2/neu proteinherstatinhuman epidermal growth factor receptor 2metastatic lymph node gene 19 proteinneuro/glioblastoma derived oncogene homologneuroblastoma/glioblastoma derived oncogene homologp185erbB2eukaryotic translation initiation factor 1protein translation factor SUI1 homologsui1iso1
Modification date2020032920200313
UniProtAcc

P04626

O60739

Ensembl transtripts involved in fusion geneENST00000584601, ENST00000406381, 
ENST00000541774, ENST00000445658, 
ENST00000540147, ENST00000584450, 
ENST00000269571, ENST00000578199, 
ENST00000540042, ENST00000584888, 
ENST00000591776, ENST00000469257, 
ENST00000310837, 
Fusion gene scores* DoF score50 X 44 X 14=3080016 X 13 X 8=1664
# samples 7317
** MAII scorelog2(73/30800*10)=-5.39889007670225
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1664*10)=-3.29104878200339
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ERBB2 [Title/Abstract] AND EIF1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointERBB2(37868701)-EIF1(39846029), # samples:1
ERBB2(37868300)-EIF1(39846029), # samples:1
ERBB2(37868701)-EIF1(39846030), # samples:1
Anticipated loss of major functional domain due to fusion event.ERBB2-EIF1 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
ERBB2-EIF1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
ERBB2-EIF1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ERBB2-EIF1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneERBB2

GO:0007165

signal transduction

10572067

HgeneERBB2

GO:0007166

cell surface receptor signaling pathway

9685399

HgeneERBB2

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

7514177

HgeneERBB2

GO:0014065

phosphatidylinositol 3-kinase signaling

7556068

HgeneERBB2

GO:0018108

peptidyl-tyrosine phosphorylation

12000754

HgeneERBB2

GO:0032886

regulation of microtubule-based process

20937854

HgeneERBB2

GO:0035556

intracellular signal transduction

19372587

HgeneERBB2

GO:0042060

wound healing

12646923

HgeneERBB2

GO:0043406

positive regulation of MAP kinase activity

10572067

HgeneERBB2

GO:0045785

positive regulation of cell adhesion

7556068

HgeneERBB2

GO:0046777

protein autophosphorylation

7556068

HgeneERBB2

GO:0050679

positive regulation of epithelial cell proliferation

10572067

HgeneERBB2

GO:0071363

cellular response to growth factor stimulus

20010870

HgeneERBB2

GO:0090314

positive regulation of protein targeting to membrane

20010870

TgeneEIF1

GO:0006446

regulation of translational initiation

22156057


check buttonFusion gene breakpoints across ERBB2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across EIF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4PEERBB2chr17

37868701

+EIF1chr17

39846029

+
ChimerDB4STADTCGA-BR-A4PEERBB2chr17

37868300

+EIF1chr17

39846029

+
ChimerDB4STADTCGA-BR-A4PE-01AERBB2chr17

37868701

+EIF1chr17

39846030

+


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Fusion Gene ORF analysis for ERBB2-EIF1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000584601ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000584601ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846029

+
5CDS-intronENST00000584601ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000406381ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000406381ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846029

+
5CDS-intronENST00000406381ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000541774ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000541774ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846029

+
5CDS-intronENST00000541774ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000445658ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000445658ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846029

+
5CDS-intronENST00000445658ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000540147ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000540147ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846029

+
5CDS-intronENST00000540147ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000584450ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000584450ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846029

+
5CDS-intronENST00000584450ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000269571ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000269571ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846029

+
5CDS-intronENST00000269571ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000578199ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000578199ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846029

+
5CDS-intronENST00000578199ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000540042ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846029

+
Frame-shiftENST00000540042ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846029

+
5CDS-intronENST00000540042ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846029

+
intron-3CDSENST00000584888ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846029

+
intron-3CDSENST00000584888ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846029

+
intron-intronENST00000584888ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846029

+
In-frameENST00000584601ENST00000591776ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000584601ENST00000469257ERBB2chr17

37868300

+EIF1chr17

39846029

+
5CDS-intronENST00000584601ENST00000310837ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000406381ENST00000591776ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000406381ENST00000469257ERBB2chr17

37868300

+EIF1chr17

39846029

+
5CDS-intronENST00000406381ENST00000310837ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000541774ENST00000591776ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000541774ENST00000469257ERBB2chr17

37868300

+EIF1chr17

39846029

+
5CDS-intronENST00000541774ENST00000310837ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000445658ENST00000591776ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000445658ENST00000469257ERBB2chr17

37868300

+EIF1chr17

39846029

+
5CDS-intronENST00000445658ENST00000310837ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000540147ENST00000591776ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000540147ENST00000469257ERBB2chr17

37868300

+EIF1chr17

39846029

+
5CDS-intronENST00000540147ENST00000310837ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000584450ENST00000591776ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000584450ENST00000469257ERBB2chr17

37868300

+EIF1chr17

39846029

+
5CDS-intronENST00000584450ENST00000310837ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000269571ENST00000591776ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000269571ENST00000469257ERBB2chr17

37868300

+EIF1chr17

39846029

+
5CDS-intronENST00000269571ENST00000310837ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000578199ENST00000591776ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000578199ENST00000469257ERBB2chr17

37868300

+EIF1chr17

39846029

+
5CDS-intronENST00000578199ENST00000310837ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000540042ENST00000591776ERBB2chr17

37868300

+EIF1chr17

39846029

+
In-frameENST00000540042ENST00000469257ERBB2chr17

37868300

+EIF1chr17

39846029

+
5CDS-intronENST00000540042ENST00000310837ERBB2chr17

37868300

+EIF1chr17

39846029

+
intron-3CDSENST00000584888ENST00000591776ERBB2chr17

37868300

+EIF1chr17

39846029

+
intron-3CDSENST00000584888ENST00000469257ERBB2chr17

37868300

+EIF1chr17

39846029

+
intron-intronENST00000584888ENST00000310837ERBB2chr17

37868300

+EIF1chr17

39846029

+
Frame-shiftENST00000584601ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000584601ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846030

+
5CDS-intronENST00000584601ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000406381ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000406381ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846030

+
5CDS-intronENST00000406381ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000541774ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000541774ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846030

+
5CDS-intronENST00000541774ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000445658ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000445658ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846030

+
5CDS-intronENST00000445658ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000540147ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000540147ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846030

+
5CDS-intronENST00000540147ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000584450ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000584450ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846030

+
5CDS-intronENST00000584450ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000269571ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000269571ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846030

+
5CDS-intronENST00000269571ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000578199ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000578199ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846030

+
5CDS-intronENST00000578199ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000540042ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846030

+
Frame-shiftENST00000540042ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846030

+
5CDS-intronENST00000540042ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846030

+
intron-3CDSENST00000584888ENST00000591776ERBB2chr17

37868701

+EIF1chr17

39846030

+
intron-3CDSENST00000584888ENST00000469257ERBB2chr17

37868701

+EIF1chr17

39846030

+
intron-intronENST00000584888ENST00000310837ERBB2chr17

37868701

+EIF1chr17

39846030

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000584601ERBB2chr1737868300+ENST00000591776EIF1chr1739846029+234217287522062436
ENST00000584601ERBB2chr1737868300+ENST00000469257EIF1chr1739846029+388117287522038428
ENST00000406381ERBB2chr1737868300+ENST00000591776EIF1chr1739846029+205514415101775421
ENST00000406381ERBB2chr1737868300+ENST00000469257EIF1chr1739846029+359414415101751413
ENST00000541774ERBB2chr1737868300+ENST00000591776EIF1chr1739846029+159097601310436
ENST00000541774ERBB2chr1737868300+ENST00000469257EIF1chr1739846029+312997601286428
ENST00000445658ERBB2chr1737868300+ENST00000591776EIF1chr1739846029+107045650790246
ENST00000445658ERBB2chr1737868300+ENST00000469257EIF1chr1739846029+260945650766238
ENST00000540147ERBB2chr1737868300+ENST00000591776EIF1chr1739846029+18731259251593522
ENST00000540147ERBB2chr1737868300+ENST00000469257EIF1chr1739846029+34121259251569514
ENST00000584450ERBB2chr1737868300+ENST00000591776EIF1chr1739846029+1850123621570522
ENST00000584450ERBB2chr1737868300+ENST00000469257EIF1chr1739846029+3389123621546514
ENST00000269571ERBB2chr1737868300+ENST00000591776EIF1chr1739846029+17941180571514485
ENST00000269571ERBB2chr1737868300+ENST00000469257EIF1chr1739846029+33331180571490477
ENST00000578199ERBB2chr1737868300+ENST00000591776EIF1chr1739846029+208614725411806421
ENST00000578199ERBB2chr1737868300+ENST00000469257EIF1chr1739846029+362514725411782413
ENST00000540042ERBB2chr1737868300+ENST00000591776EIF1chr1739846029+171110971661431421
ENST00000540042ERBB2chr1737868300+ENST00000469257EIF1chr1739846029+325010971661407413

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000584601ENST00000591776ERBB2chr1737868300+EIF1chr1739846029+0.0095476770.9904523
ENST00000584601ENST00000469257ERBB2chr1737868300+EIF1chr1739846029+0.0043257430.9956742
ENST00000406381ENST00000591776ERBB2chr1737868300+EIF1chr1739846029+0.0054763360.99452364
ENST00000406381ENST00000469257ERBB2chr1737868300+EIF1chr1739846029+0.0019784840.9980215
ENST00000541774ENST00000591776ERBB2chr1737868300+EIF1chr1739846029+0.0123624220.9876375
ENST00000541774ENST00000469257ERBB2chr1737868300+EIF1chr1739846029+0.0040364670.99596345
ENST00000445658ENST00000591776ERBB2chr1737868300+EIF1chr1739846029+0.0097376280.9902624
ENST00000445658ENST00000469257ERBB2chr1737868300+EIF1chr1739846029+0.0090486850.9909513
ENST00000540147ENST00000591776ERBB2chr1737868300+EIF1chr1739846029+0.018545860.98145413
ENST00000540147ENST00000469257ERBB2chr1737868300+EIF1chr1739846029+0.0070788510.9929212
ENST00000584450ENST00000591776ERBB2chr1737868300+EIF1chr1739846029+0.0199696180.98003036
ENST00000584450ENST00000469257ERBB2chr1737868300+EIF1chr1739846029+0.007333980.99266607
ENST00000269571ENST00000591776ERBB2chr1737868300+EIF1chr1739846029+0.01975750.98024255
ENST00000269571ENST00000469257ERBB2chr1737868300+EIF1chr1739846029+0.0071896510.99281037
ENST00000578199ENST00000591776ERBB2chr1737868300+EIF1chr1739846029+0.0040935710.99590635
ENST00000578199ENST00000469257ERBB2chr1737868300+EIF1chr1739846029+0.0016627810.99833715
ENST00000540042ENST00000591776ERBB2chr1737868300+EIF1chr1739846029+0.0054860140.994514
ENST00000540042ENST00000469257ERBB2chr1737868300+EIF1chr1739846029+0.0017383720.99826163

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Fusion Genomic Features for ERBB2-EIF1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ERBB2chr1737868300+EIF1chr1739846029+0.0083673480.99163264
ERBB2chr1737868701+EIF1chr1739846029+4.40E-070.9999995
ERBB2chr1737868701+EIF1chr1739846029+4.40E-070.9999995
ERBB2chr1737868300+EIF1chr1739846029+0.0083673480.99163264
ERBB2chr1737868701+EIF1chr1739846029+4.40E-070.9999995
ERBB2chr1737868701+EIF1chr1739846029+4.40E-070.9999995

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ERBB2-EIF1


check button Go to

FGviewer for the breakpoints of chr17:37868300-chr17:39846029

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ERBB2

P04626

EIF1

O60739

FUNCTION: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. {ECO:0000305}.; FUNCTION: In the nucleus is involved in transcriptional regulation. Associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. Implicated in transcriptional activation of CDKN1A; the function involves STAT3 and SRC. Involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth. {ECO:0000269|PubMed:10358079, ECO:0000269|PubMed:15380516, ECO:0000269|PubMed:21555369}.FUNCTION: Probably involved in translation.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneERBB2chr17:37868300chr17:39846029ENST00000269571+827720_987340.33333333333331256.0DomainProtein kinase
HgeneERBB2chr17:37868300chr17:39846029ENST00000541774+827720_987325.33333333333331241.0DomainProtein kinase
HgeneERBB2chr17:37868300chr17:39846029ENST00000269571+827676_689340.33333333333331256.0MotifNote=Nuclear localization signal
HgeneERBB2chr17:37868300chr17:39846029ENST00000541774+827676_689325.33333333333331241.0MotifNote=Nuclear localization signal
HgeneERBB2chr17:37868300chr17:39846029ENST00000269571+827726_734340.33333333333331256.0Nucleotide bindingATP
HgeneERBB2chr17:37868300chr17:39846029ENST00000541774+827726_734325.33333333333331241.0Nucleotide bindingATP
HgeneERBB2chr17:37868300chr17:39846029ENST00000269571+82723_652340.33333333333331256.0Topological domainExtracellular
HgeneERBB2chr17:37868300chr17:39846029ENST00000269571+827676_1255340.33333333333331256.0Topological domainCytoplasmic
HgeneERBB2chr17:37868300chr17:39846029ENST00000541774+82723_652325.33333333333331241.0Topological domainExtracellular
HgeneERBB2chr17:37868300chr17:39846029ENST00000541774+827676_1255325.33333333333331241.0Topological domainCytoplasmic
HgeneERBB2chr17:37868300chr17:39846029ENST00000269571+827653_675340.33333333333331256.0TransmembraneHelical
HgeneERBB2chr17:37868300chr17:39846029ENST00000541774+827653_675325.33333333333331241.0TransmembraneHelical


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Fusion Gene Sequence for ERBB2-EIF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000584601_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=2342nt_BP=1728nt
AGTACGCAGTCGCGGTACACCGGCTCACGGTCGCCCTGGGAGCCGCTCGCCAGCGCCGCTGCCCCAGCTAGCAGGACCAACCGCGCCGCC
AGGCCGGCCATCCTTTCTCCCTGGCTCGCCGCCGGGGGAGGAGCTTAGGAGTATGAAGCTTCCACTTCCGGAGTAACCGGAAGTTCCTGT
GTTCTTTATTCTACTCTCCGCTGAAGTCCACACAGTTTAAATTAAAGTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCT
GCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGAAGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTT
TTGAGTCGCAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCC
AGCACAGAATTTGGCTTATGCCTACTCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTGGC
AAAGCAAAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCCAGGA
CAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTGTTGTGGACATGCAC
AAAAGTGAGATACTTCAAAGATTCCAGAAGATATGCCCCGGGGGTCCTGGAAGCCACAAGTGTGCACCGGCACAGACATGAAGCTGCGGC
TCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACC
TGCCCACCAATGCCAGCCTGTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCC
CACTGCAGAGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACA
ATACCACCCCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGA
TCCAGCGGAACCCCCAGCTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAG
ACACCAACCGCTCTCGGGCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCC
TGACGCGCACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCA
CGGGCCCCAAGCACTCTGACTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACA
ACACAGACACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTT
CTACGGACGTGGGATCCTGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCA
GCAAGCCCTGTGCCCGAGACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAA
TTCAACAGAGAAACGGCAGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGA
AAAAGTTTGCCTGCAATGGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCC
AGTTCCTCGTAGAGATTGGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTG
GGGTCCGCTTTTAACTTGGACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAA
CAGAGGTCAAGCAATAGGCGCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTAC
AAACAACTATGGCCGGAACCTCCTCAGCTCTCCCTCTGCAGAGTTCCCTACCCTAAGAGAATGTTACCACCTGAACAGTCCTCGGTGAAT

>In-frame_ENST00000584601_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=436AA_start in transcript=752_stop in transcript=2062
MPRGSWKPQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGT
QLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPC
SPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNP
EGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLT

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>In-frame_ENST00000584601_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=3881nt_BP=1728nt
AGTACGCAGTCGCGGTACACCGGCTCACGGTCGCCCTGGGAGCCGCTCGCCAGCGCCGCTGCCCCAGCTAGCAGGACCAACCGCGCCGCC
AGGCCGGCCATCCTTTCTCCCTGGCTCGCCGCCGGGGGAGGAGCTTAGGAGTATGAAGCTTCCACTTCCGGAGTAACCGGAAGTTCCTGT
GTTCTTTATTCTACTCTCCGCTGAAGTCCACACAGTTTAAATTAAAGTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCT
GCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGAAGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTT
TTGAGTCGCAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCC
AGCACAGAATTTGGCTTATGCCTACTCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTGGC
AAAGCAAAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCCAGGA
CAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTGTTGTGGACATGCAC
AAAAGTGAGATACTTCAAAGATTCCAGAAGATATGCCCCGGGGGTCCTGGAAGCCACAAGTGTGCACCGGCACAGACATGAAGCTGCGGC
TCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACC
TGCCCACCAATGCCAGCCTGTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCC
CACTGCAGAGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACA
ATACCACCCCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGA
TCCAGCGGAACCCCCAGCTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAG
ACACCAACCGCTCTCGGGCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCC
TGACGCGCACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCA
CGGGCCCCAAGCACTCTGACTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACA
ACACAGACACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTT
CTACGGACGTGGGATCCTGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCA
GCAAGCCCTGTGCCCGAGACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAA
TTCAACAGAGAAACGGCAGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGA
AAAAGTTTGCCTGCAATGGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCC
AGTTCCTCGTAGAGATTGGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTTAAGTGCTTGTGGCTCACTGAAGCTTAAGTGAGG
ATTTCCTTGCAATGAGTAGAATTTCCCTTCTCTCCCTTGTCACAGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCG
CTTTTAACTTGGACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGT
CAAGCAATAGGCGCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAAC
TATGGCCGGAACCTCCTCAGCTCTCCCTCTGCAGAGTTCCCTACCCTAAGAGAATGTTACCACCTGAACAGTCCTCGGTGAATCTGAGAG
GAGAGGATGGGGTAAGGCAGAAGCACCAGCTGTACTACTAGAAGGGAGCTTTTGGTGGTAGATCCCCTGGTGTCTCCAACCTGACTAGGT
GGACAGAGCTCAAAGAGGCCCTCTTACCGCTAGCGAGGTGATAGGACATCTGGCTTGCCACAAAGGTCTGTTCGACCAGACATATCCTAG
CTAAGGGATGTCCAAACATCAGAATGTGAGGCCAACCTTCTATCAGAGTTAAACTTTTGACAAGGGAACAAATCTCAAACTGATCCATCA
GTCATGTAGCTAGCTGTAGAGCTTGCAACTTAATAGCAGCAGCTGCCCAATGCCATGTGAAGTAACAAACTGGTTTTTGGTTTTTTTTTC
CCCTTCAGTTTTAATGTTATGTGTAATGTATTTAAACCCTTATTTAAATAAAACTTGTTTTCAGAAATACCTGACTTGCAGATTATTTAT
ATATAGTCGATCTTGTGCATATAAAGGAACCATAGAAATGGGCAGTGGAGGATTCGTCCACACCCACAGCTTCTCAACGGGCCTGAATTT
GGCCAAGAAAAACCTTTATGAGCTTGTCCCTCTCTGGTCAACTGGTTTTTTGTTCGTTTGTTTTTTGAGACAGGTTTGCCCTTGTTGCCC
AGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAACCTCCACCTCAGGTTCAAGCAATTGTCGTGCCTCAGCCTCCCTAGTAGCTGG
GATTACAGGCACCATGCCCAGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGCCAGGCTGGTCTTGAACACCTGGCC
TCAAGTGATCTGCCTGTCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCCAGCAGGTCAACTGTTTTTGCAAGCAT
TTAGCCAGAGTCATGCTGTGCTGTTAATCAGTGTCCTGGAGAATGGGTTGCTTGGAAATCTTGGCGCCCCCTCAGTAGTAACAGCCTTGG
TTTAAGGGCGCAGAGTGGAGAGTAAATGCAAGGGCTATAACAAGGGCATTCATGCTGTGGGTTAAGATCCACAAATCGCTAGGAATGTGT
ATACTCTGGGTAGTAAGTTTGTAGTATTAGAAGGTTTAATGACAAGTATTTGAAGAGCTGAAGTTAAGTGTTGGGAGGCCATCCCTTATG
AAGGACAATGAATGGCAAGTAAAAGACCAAGTTCTGTTCCTGGGTCCATTAATTTAGTTAAAAAGGCAAAGTTCTTTCAGCACACATATC
TGCATGCAGTCACGTGCTGCCTAAGGATGCTTCATTCAACAATGAGCCTCACAGCCGTGCTACACAATAAGATTATAATACTGTATTTTT
ACTGTACCTTTTAACATTGTGTTACAATGGCCTACAAGAAGCTTGTGTGGATGGCTTTGAATGTGGCCCAACACGAACTAATAAATTTTG

>In-frame_ENST00000584601_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=428AA_start in transcript=752_stop in transcript=2038
MPRGSWKPQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGT
QLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPC
SPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNP
EGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLT

--------------------------------------------------------------
>In-frame_ENST00000406381_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=2055nt_BP=1441nt
GTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGAAGGCGGACGC
CTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGTCGCAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCC
ATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCCAGCACAGAATTTGGCTTATGCCAAATCCGAAAATATTGTGACCAGG
AACCATTCTGTCCAACTCTTCTATTTCAGGTGGCAAAGCAAAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCAC
AGATAAAACGGGGGCACCAGTAGAATGGCCAGGACAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGT
GATGAGAGTGACATGTACTGTTGTGGACATGCACAAAAGTGAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAG
ACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGC
CTGTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCAGAGGCTGCGG
ATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAATACCACCCCTGTCACA
GGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGATCCAGCGGAACCCCCAG
CTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGACACCAACCGCTCTCGG
GCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCTGACGCGCACTGTCTGT
GCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCCAAGCACTCT
GACTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAACACAGACACGTTTGAG
TCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGACGTGGGATCC
TGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTGCCCGA
GACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAGAGAAACGGC
AGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTTGCCTGCAAT
GGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTCGTAGAGATT
GGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGCTTTTAACTT
GGACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTCAAGCAATAG
GCGCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACTATGGCCGGA

>In-frame_ENST00000406381_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=421AA_start in transcript=510_stop in transcript=1775
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE
DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLV

--------------------------------------------------------------
>In-frame_ENST00000406381_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=3594nt_BP=1441nt
GTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGAAGGCGGACGC
CTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGTCGCAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCC
ATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCCAGCACAGAATTTGGCTTATGCCAAATCCGAAAATATTGTGACCAGG
AACCATTCTGTCCAACTCTTCTATTTCAGGTGGCAAAGCAAAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCAC
AGATAAAACGGGGGCACCAGTAGAATGGCCAGGACAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGT
GATGAGAGTGACATGTACTGTTGTGGACATGCACAAAAGTGAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAG
ACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGC
CTGTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCAGAGGCTGCGG
ATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAATACCACCCCTGTCACA
GGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGATCCAGCGGAACCCCCAG
CTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGACACCAACCGCTCTCGG
GCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCTGACGCGCACTGTCTGT
GCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCCAAGCACTCT
GACTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAACACAGACACGTTTGAG
TCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGACGTGGGATCC
TGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTGCCCGA
GACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAGAGAAACGGC
AGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTTGCCTGCAAT
GGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTCGTAGAGATT
GGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTTAAGTGCTTGTGGCTCACTGAAGCTTAAGTGAGGATTTCCTTGCAATGAGT
AGAATTTCCCTTCTCTCCCTTGTCACAGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGCTTTTAACTTGGACTAG
TGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTCAAGCAATAGGCGCCTG
GCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACTATGGCCGGAACCTCCT
CAGCTCTCCCTCTGCAGAGTTCCCTACCCTAAGAGAATGTTACCACCTGAACAGTCCTCGGTGAATCTGAGAGGAGAGGATGGGGTAAGG
CAGAAGCACCAGCTGTACTACTAGAAGGGAGCTTTTGGTGGTAGATCCCCTGGTGTCTCCAACCTGACTAGGTGGACAGAGCTCAAAGAG
GCCCTCTTACCGCTAGCGAGGTGATAGGACATCTGGCTTGCCACAAAGGTCTGTTCGACCAGACATATCCTAGCTAAGGGATGTCCAAAC
ATCAGAATGTGAGGCCAACCTTCTATCAGAGTTAAACTTTTGACAAGGGAACAAATCTCAAACTGATCCATCAGTCATGTAGCTAGCTGT
AGAGCTTGCAACTTAATAGCAGCAGCTGCCCAATGCCATGTGAAGTAACAAACTGGTTTTTGGTTTTTTTTTCCCCTTCAGTTTTAATGT
TATGTGTAATGTATTTAAACCCTTATTTAAATAAAACTTGTTTTCAGAAATACCTGACTTGCAGATTATTTATATATAGTCGATCTTGTG
CATATAAAGGAACCATAGAAATGGGCAGTGGAGGATTCGTCCACACCCACAGCTTCTCAACGGGCCTGAATTTGGCCAAGAAAAACCTTT
ATGAGCTTGTCCCTCTCTGGTCAACTGGTTTTTTGTTCGTTTGTTTTTTGAGACAGGTTTGCCCTTGTTGCCCAGGCTGGAGTGCAGTGG
CACAATCTCGGCTCACTGCAACCTCCACCTCAGGTTCAAGCAATTGTCGTGCCTCAGCCTCCCTAGTAGCTGGGATTACAGGCACCATGC
CCAGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGCCAGGCTGGTCTTGAACACCTGGCCTCAAGTGATCTGCCTGT
CTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCCAGCAGGTCAACTGTTTTTGCAAGCATTTAGCCAGAGTCATGCT
GTGCTGTTAATCAGTGTCCTGGAGAATGGGTTGCTTGGAAATCTTGGCGCCCCCTCAGTAGTAACAGCCTTGGTTTAAGGGCGCAGAGTG
GAGAGTAAATGCAAGGGCTATAACAAGGGCATTCATGCTGTGGGTTAAGATCCACAAATCGCTAGGAATGTGTATACTCTGGGTAGTAAG
TTTGTAGTATTAGAAGGTTTAATGACAAGTATTTGAAGAGCTGAAGTTAAGTGTTGGGAGGCCATCCCTTATGAAGGACAATGAATGGCA
AGTAAAAGACCAAGTTCTGTTCCTGGGTCCATTAATTTAGTTAAAAAGGCAAAGTTCTTTCAGCACACATATCTGCATGCAGTCACGTGC
TGCCTAAGGATGCTTCATTCAACAATGAGCCTCACAGCCGTGCTACACAATAAGATTATAATACTGTATTTTTACTGTACCTTTTAACAT

>In-frame_ENST00000406381_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=413AA_start in transcript=510_stop in transcript=1751
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE
DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLV

--------------------------------------------------------------
>In-frame_ENST00000541774_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=1590nt_BP=976nt
ATGCCCCGGGGGTCCTGGAAGCCACAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATG
CTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAG
GATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCAGAGGCTGCGGATTGTGCGAGGCACC
CAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAATACCACCCCTGTCACAGGGGCCTCCCCAGGA
GGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGATCCAGCGGAACCCCCAGCTCTGCTACCAGGAC
ACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGACACCAACCGCTCTCGGGCCTGCCACCCCTGT
TCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCTGACGCGCACTGTCTGTGCCGGTGGCTGTGCC
CGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCCAAGCACTCTGACTGCCTGGCCTGC
CTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAACACAGACACGTTTGAGTCCATGCCCAATCCC
GAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGACGTGGGATCCTGCACCCTCGTCTGC
CCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTGCCCGAGACCCCTTTGCTGAT
GCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAGAGAAACGGCAGGAAGACCCTTACT
ACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTTGCCTGCAATGGTACTGTAATTGAG
CATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTCGTAGAGATTGGACTGGCTAAGGAC
GATCAGCTGAAGGTTCATGGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGCTTTTAACTTGGACTAGTGTAACTC
CTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTCAAGCAATAGGCGCCTGGCAGTGTC
AAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACTATGGCCGGAACCTCCTCAGCTCTC

>In-frame_ENST00000541774_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=436AA_start in transcript=0_stop in transcript=1310
MPRGSWKPQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGT
QLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPC
SPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNP
EGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLT

--------------------------------------------------------------
>In-frame_ENST00000541774_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=3129nt_BP=976nt
ATGCCCCGGGGGTCCTGGAAGCCACAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATG
CTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAG
GATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCAGAGGCTGCGGATTGTGCGAGGCACC
CAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAATACCACCCCTGTCACAGGGGCCTCCCCAGGA
GGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGATCCAGCGGAACCCCCAGCTCTGCTACCAGGAC
ACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGACACCAACCGCTCTCGGGCCTGCCACCCCTGT
TCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCTGACGCGCACTGTCTGTGCCGGTGGCTGTGCC
CGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCCAAGCACTCTGACTGCCTGGCCTGC
CTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAACACAGACACGTTTGAGTCCATGCCCAATCCC
GAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGACGTGGGATCCTGCACCCTCGTCTGC
CCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTGCCCGAGACCCCTTTGCTGAT
GCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAGAGAAACGGCAGGAAGACCCTTACT
ACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTTGCCTGCAATGGTACTGTAATTGAG
CATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTCGTAGAGATTGGACTGGCTAAGGAC
GATCAGCTGAAGGTTCATGGGTTTTAAGTGCTTGTGGCTCACTGAAGCTTAAGTGAGGATTTCCTTGCAATGAGTAGAATTTCCCTTCTC
TCCCTTGTCACAGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGCTTTTAACTTGGACTAGTGTAACTCCTTCATG
CAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTCAAGCAATAGGCGCCTGGCAGTGTCAAGCCTG
AAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACTATGGCCGGAACCTCCTCAGCTCTCCCTCTGC
AGAGTTCCCTACCCTAAGAGAATGTTACCACCTGAACAGTCCTCGGTGAATCTGAGAGGAGAGGATGGGGTAAGGCAGAAGCACCAGCTG
TACTACTAGAAGGGAGCTTTTGGTGGTAGATCCCCTGGTGTCTCCAACCTGACTAGGTGGACAGAGCTCAAAGAGGCCCTCTTACCGCTA
GCGAGGTGATAGGACATCTGGCTTGCCACAAAGGTCTGTTCGACCAGACATATCCTAGCTAAGGGATGTCCAAACATCAGAATGTGAGGC
CAACCTTCTATCAGAGTTAAACTTTTGACAAGGGAACAAATCTCAAACTGATCCATCAGTCATGTAGCTAGCTGTAGAGCTTGCAACTTA
ATAGCAGCAGCTGCCCAATGCCATGTGAAGTAACAAACTGGTTTTTGGTTTTTTTTTCCCCTTCAGTTTTAATGTTATGTGTAATGTATT
TAAACCCTTATTTAAATAAAACTTGTTTTCAGAAATACCTGACTTGCAGATTATTTATATATAGTCGATCTTGTGCATATAAAGGAACCA
TAGAAATGGGCAGTGGAGGATTCGTCCACACCCACAGCTTCTCAACGGGCCTGAATTTGGCCAAGAAAAACCTTTATGAGCTTGTCCCTC
TCTGGTCAACTGGTTTTTTGTTCGTTTGTTTTTTGAGACAGGTTTGCCCTTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCA
CTGCAACCTCCACCTCAGGTTCAAGCAATTGTCGTGCCTCAGCCTCCCTAGTAGCTGGGATTACAGGCACCATGCCCAGCTAACTTTTGT
ATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGCCAGGCTGGTCTTGAACACCTGGCCTCAAGTGATCTGCCTGTCTTGGCCTCCCAAAG
TGCTGGGATTACAGGCATGAGCCACCATGCCCAGCAGGTCAACTGTTTTTGCAAGCATTTAGCCAGAGTCATGCTGTGCTGTTAATCAGT
GTCCTGGAGAATGGGTTGCTTGGAAATCTTGGCGCCCCCTCAGTAGTAACAGCCTTGGTTTAAGGGCGCAGAGTGGAGAGTAAATGCAAG
GGCTATAACAAGGGCATTCATGCTGTGGGTTAAGATCCACAAATCGCTAGGAATGTGTATACTCTGGGTAGTAAGTTTGTAGTATTAGAA
GGTTTAATGACAAGTATTTGAAGAGCTGAAGTTAAGTGTTGGGAGGCCATCCCTTATGAAGGACAATGAATGGCAAGTAAAAGACCAAGT
TCTGTTCCTGGGTCCATTAATTTAGTTAAAAAGGCAAAGTTCTTTCAGCACACATATCTGCATGCAGTCACGTGCTGCCTAAGGATGCTT
CATTCAACAATGAGCCTCACAGCCGTGCTACACAATAAGATTATAATACTGTATTTTTACTGTACCTTTTAACATTGTGTTACAATGGCC

>In-frame_ENST00000541774_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=428AA_start in transcript=0_stop in transcript=1286
MPRGSWKPQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGT
QLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPC
SPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNP
EGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLT

--------------------------------------------------------------
>In-frame_ENST00000445658_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=1070nt_BP=456nt
GCGCTTGCTCCCAATCACAGGAGAAGGAGGAGGTGGAGGAGGAGGGCTGCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCC
CCTCCATTGGGACCGGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCC
CCCACCCCTCGCAGCACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGC
TGGCGGCCTTGTGCCGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGACAACTACCTTTCTACGGACGTGG
GATCCTGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTG
CCCGAGACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAGAGAA
ACGGCAGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTTGCCT
GCAATGGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTCGTAG
AGATTGGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGCTTTT
AACTTGGACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTCAAGC
AATAGGCGCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACTATGG

>In-frame_ENST00000445658_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=246AA_start in transcript=50_stop in transcript=790
MRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQDNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYD

--------------------------------------------------------------
>In-frame_ENST00000445658_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=2609nt_BP=456nt
GCGCTTGCTCCCAATCACAGGAGAAGGAGGAGGTGGAGGAGGAGGGCTGCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCC
CCTCCATTGGGACCGGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCC
CCCACCCCTCGCAGCACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGC
TGGCGGCCTTGTGCCGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGACAACTACCTTTCTACGGACGTGG
GATCCTGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTG
CCCGAGACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAGAGAA
ACGGCAGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTTGCCT
GCAATGGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTCGTAG
AGATTGGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTTAAGTGCTTGTGGCTCACTGAAGCTTAAGTGAGGATTTCCTTGCAA
TGAGTAGAATTTCCCTTCTCTCCCTTGTCACAGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGCTTTTAACTTGG
ACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTCAAGCAATAGGC
GCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACTATGGCCGGAAC
CTCCTCAGCTCTCCCTCTGCAGAGTTCCCTACCCTAAGAGAATGTTACCACCTGAACAGTCCTCGGTGAATCTGAGAGGAGAGGATGGGG
TAAGGCAGAAGCACCAGCTGTACTACTAGAAGGGAGCTTTTGGTGGTAGATCCCCTGGTGTCTCCAACCTGACTAGGTGGACAGAGCTCA
AAGAGGCCCTCTTACCGCTAGCGAGGTGATAGGACATCTGGCTTGCCACAAAGGTCTGTTCGACCAGACATATCCTAGCTAAGGGATGTC
CAAACATCAGAATGTGAGGCCAACCTTCTATCAGAGTTAAACTTTTGACAAGGGAACAAATCTCAAACTGATCCATCAGTCATGTAGCTA
GCTGTAGAGCTTGCAACTTAATAGCAGCAGCTGCCCAATGCCATGTGAAGTAACAAACTGGTTTTTGGTTTTTTTTTCCCCTTCAGTTTT
AATGTTATGTGTAATGTATTTAAACCCTTATTTAAATAAAACTTGTTTTCAGAAATACCTGACTTGCAGATTATTTATATATAGTCGATC
TTGTGCATATAAAGGAACCATAGAAATGGGCAGTGGAGGATTCGTCCACACCCACAGCTTCTCAACGGGCCTGAATTTGGCCAAGAAAAA
CCTTTATGAGCTTGTCCCTCTCTGGTCAACTGGTTTTTTGTTCGTTTGTTTTTTGAGACAGGTTTGCCCTTGTTGCCCAGGCTGGAGTGC
AGTGGCACAATCTCGGCTCACTGCAACCTCCACCTCAGGTTCAAGCAATTGTCGTGCCTCAGCCTCCCTAGTAGCTGGGATTACAGGCAC
CATGCCCAGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGCCAGGCTGGTCTTGAACACCTGGCCTCAAGTGATCTG
CCTGTCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCCAGCAGGTCAACTGTTTTTGCAAGCATTTAGCCAGAGTC
ATGCTGTGCTGTTAATCAGTGTCCTGGAGAATGGGTTGCTTGGAAATCTTGGCGCCCCCTCAGTAGTAACAGCCTTGGTTTAAGGGCGCA
GAGTGGAGAGTAAATGCAAGGGCTATAACAAGGGCATTCATGCTGTGGGTTAAGATCCACAAATCGCTAGGAATGTGTATACTCTGGGTA
GTAAGTTTGTAGTATTAGAAGGTTTAATGACAAGTATTTGAAGAGCTGAAGTTAAGTGTTGGGAGGCCATCCCTTATGAAGGACAATGAA
TGGCAAGTAAAAGACCAAGTTCTGTTCCTGGGTCCATTAATTTAGTTAAAAAGGCAAAGTTCTTTCAGCACACATATCTGCATGCAGTCA
CGTGCTGCCTAAGGATGCTTCATTCAACAATGAGCCTCACAGCCGTGCTACACAATAAGATTATAATACTGTATTTTTACTGTACCTTTT

>In-frame_ENST00000445658_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=238AA_start in transcript=50_stop in transcript=766
MRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQDNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYD

--------------------------------------------------------------
>In-frame_ENST00000540147_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=1873nt_BP=1259nt
GGAGGAGGTGGAGGAGGAGGGCTGCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCGGAGAAACCAG
GGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAGCACCCCGCGCC
CCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGCCGCTGGGGGCT
CCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGAC
CCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCT
GTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCAGAGGCTGCGGAT
TGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAATACCACCCCTGTCACAGG
GGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGATCCAGCGGAACCCCCAGCT
CTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGACACCAACCGCTCTCGGGC
CTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCTGACGCGCACTGTCTGTGC
CGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCCAAGCACTCTGA
CTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAACACAGACACGTTTGAGTC
CATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGACGTGGGATCCTG
CACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTGCCCGAGA
CCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAGAGAAACGGCAG
GAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTTGCCTGCAATGG
TACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTCGTAGAGATTGG
ACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGCTTTTAACTTGG
ACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTCAAGCAATAGGC
GCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACTATGGCCGGAAC

>In-frame_ENST00000540147_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=522AA_start in transcript=25_stop in transcript=1593
MRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFE
DNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMC
KGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRY
TFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQG

--------------------------------------------------------------
>In-frame_ENST00000540147_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=3412nt_BP=1259nt
GGAGGAGGTGGAGGAGGAGGGCTGCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCGGAGAAACCAG
GGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAGCACCCCGCGCC
CCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGCCGCTGGGGGCT
CCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGAC
CCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCT
GTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCAGAGGCTGCGGAT
TGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAATACCACCCCTGTCACAGG
GGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGATCCAGCGGAACCCCCAGCT
CTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGACACCAACCGCTCTCGGGC
CTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCTGACGCGCACTGTCTGTGC
CGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCCAAGCACTCTGA
CTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAACACAGACACGTTTGAGTC
CATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGACGTGGGATCCTG
CACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTGCCCGAGA
CCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAGAGAAACGGCAG
GAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTTGCCTGCAATGG
TACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTCGTAGAGATTGG
ACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTTAAGTGCTTGTGGCTCACTGAAGCTTAAGTGAGGATTTCCTTGCAATGAGTAG
AATTTCCCTTCTCTCCCTTGTCACAGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGCTTTTAACTTGGACTAGTG
TAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTCAAGCAATAGGCGCCTGGC
AGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACTATGGCCGGAACCTCCTCA
GCTCTCCCTCTGCAGAGTTCCCTACCCTAAGAGAATGTTACCACCTGAACAGTCCTCGGTGAATCTGAGAGGAGAGGATGGGGTAAGGCA
GAAGCACCAGCTGTACTACTAGAAGGGAGCTTTTGGTGGTAGATCCCCTGGTGTCTCCAACCTGACTAGGTGGACAGAGCTCAAAGAGGC
CCTCTTACCGCTAGCGAGGTGATAGGACATCTGGCTTGCCACAAAGGTCTGTTCGACCAGACATATCCTAGCTAAGGGATGTCCAAACAT
CAGAATGTGAGGCCAACCTTCTATCAGAGTTAAACTTTTGACAAGGGAACAAATCTCAAACTGATCCATCAGTCATGTAGCTAGCTGTAG
AGCTTGCAACTTAATAGCAGCAGCTGCCCAATGCCATGTGAAGTAACAAACTGGTTTTTGGTTTTTTTTTCCCCTTCAGTTTTAATGTTA
TGTGTAATGTATTTAAACCCTTATTTAAATAAAACTTGTTTTCAGAAATACCTGACTTGCAGATTATTTATATATAGTCGATCTTGTGCA
TATAAAGGAACCATAGAAATGGGCAGTGGAGGATTCGTCCACACCCACAGCTTCTCAACGGGCCTGAATTTGGCCAAGAAAAACCTTTAT
GAGCTTGTCCCTCTCTGGTCAACTGGTTTTTTGTTCGTTTGTTTTTTGAGACAGGTTTGCCCTTGTTGCCCAGGCTGGAGTGCAGTGGCA
CAATCTCGGCTCACTGCAACCTCCACCTCAGGTTCAAGCAATTGTCGTGCCTCAGCCTCCCTAGTAGCTGGGATTACAGGCACCATGCCC
AGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGCCAGGCTGGTCTTGAACACCTGGCCTCAAGTGATCTGCCTGTCT
TGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCCAGCAGGTCAACTGTTTTTGCAAGCATTTAGCCAGAGTCATGCTGT
GCTGTTAATCAGTGTCCTGGAGAATGGGTTGCTTGGAAATCTTGGCGCCCCCTCAGTAGTAACAGCCTTGGTTTAAGGGCGCAGAGTGGA
GAGTAAATGCAAGGGCTATAACAAGGGCATTCATGCTGTGGGTTAAGATCCACAAATCGCTAGGAATGTGTATACTCTGGGTAGTAAGTT
TGTAGTATTAGAAGGTTTAATGACAAGTATTTGAAGAGCTGAAGTTAAGTGTTGGGAGGCCATCCCTTATGAAGGACAATGAATGGCAAG
TAAAAGACCAAGTTCTGTTCCTGGGTCCATTAATTTAGTTAAAAAGGCAAAGTTCTTTCAGCACACATATCTGCATGCAGTCACGTGCTG
CCTAAGGATGCTTCATTCAACAATGAGCCTCACAGCCGTGCTACACAATAAGATTATAATACTGTATTTTTACTGTACCTTTTAACATTG

>In-frame_ENST00000540147_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=514AA_start in transcript=25_stop in transcript=1569
MRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFE
DNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMC
KGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRY
TFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQG

--------------------------------------------------------------
>In-frame_ENST00000584450_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=1850nt_BP=1236nt
GCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCGGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGC
GCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAGCACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCA
GCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGCCGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCG
GAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACC
TCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGGATATCCAGG
AGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCAGAGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTG
AGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAATACCACCCCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGG
AGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGATCCAGCGGAACCCCCAGCTCTGCTACCAGGACACGATTTTGT
GGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGACACCAACCGCTCTCGGGCCTGCCACCCCTGTTCTCCGATGT
GTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCTGACGCGCACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGG
GGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCCAAGCACTCTGACTGCCTGGCCTGCCTCCACTTCA
ACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAACACAGACACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGT
ATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGACGTGGGATCCTGCACCCTCGTCTGCCCCCTGCACA
ACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTGCCCGAGACCCCTTTGCTGATGCAAGTAAGG
GTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAGAGAAACGGCAGGAAGACCCTTACTACTGTCCAAG
GGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTTGCCTGCAATGGTACTGTAATTGAGCATCCGGAAT
ATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTCGTAGAGATTGGACTGGCTAAGGACGATCAGCTGA
AGGTTCATGGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGCTTTTAACTTGGACTAGTGTAACTCCTTCATGCAA
TAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTCAAGCAATAGGCGCCTGGCAGTGTCAAGCCTGAAA
CCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACTATGGCCGGAACCTCCTCAGCTCTCCCTCTGCAGA

>In-frame_ENST00000584450_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=522AA_start in transcript=2_stop in transcript=1570
LRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFE
DNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMC
KGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRY
TFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQG

--------------------------------------------------------------
>In-frame_ENST00000584450_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=3389nt_BP=1236nt
GCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCGGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGC
GCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAGCACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCA
GCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGCCGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCG
GAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACC
TCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGGATATCCAGG
AGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCAGAGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTG
AGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAATACCACCCCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGG
AGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGATCCAGCGGAACCCCCAGCTCTGCTACCAGGACACGATTTTGT
GGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGACACCAACCGCTCTCGGGCCTGCCACCCCTGTTCTCCGATGT
GTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCTGACGCGCACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGG
GGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCCAAGCACTCTGACTGCCTGGCCTGCCTCCACTTCA
ACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAACACAGACACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGT
ATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGACGTGGGATCCTGCACCCTCGTCTGCCCCCTGCACA
ACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTGCCCGAGACCCCTTTGCTGATGCAAGTAAGG
GTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAGAGAAACGGCAGGAAGACCCTTACTACTGTCCAAG
GGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTTGCCTGCAATGGTACTGTAATTGAGCATCCGGAAT
ATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTCGTAGAGATTGGACTGGCTAAGGACGATCAGCTGA
AGGTTCATGGGTTTTAAGTGCTTGTGGCTCACTGAAGCTTAAGTGAGGATTTCCTTGCAATGAGTAGAATTTCCCTTCTCTCCCTTGTCA
CAGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGCTTTTAACTTGGACTAGTGTAACTCCTTCATGCAATAAACTG
AAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTCAAGCAATAGGCGCCTGGCAGTGTCAAGCCTGAAACCAAGCA
ATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACTATGGCCGGAACCTCCTCAGCTCTCCCTCTGCAGAGTTCCCT
ACCCTAAGAGAATGTTACCACCTGAACAGTCCTCGGTGAATCTGAGAGGAGAGGATGGGGTAAGGCAGAAGCACCAGCTGTACTACTAGA
AGGGAGCTTTTGGTGGTAGATCCCCTGGTGTCTCCAACCTGACTAGGTGGACAGAGCTCAAAGAGGCCCTCTTACCGCTAGCGAGGTGAT
AGGACATCTGGCTTGCCACAAAGGTCTGTTCGACCAGACATATCCTAGCTAAGGGATGTCCAAACATCAGAATGTGAGGCCAACCTTCTA
TCAGAGTTAAACTTTTGACAAGGGAACAAATCTCAAACTGATCCATCAGTCATGTAGCTAGCTGTAGAGCTTGCAACTTAATAGCAGCAG
CTGCCCAATGCCATGTGAAGTAACAAACTGGTTTTTGGTTTTTTTTTCCCCTTCAGTTTTAATGTTATGTGTAATGTATTTAAACCCTTA
TTTAAATAAAACTTGTTTTCAGAAATACCTGACTTGCAGATTATTTATATATAGTCGATCTTGTGCATATAAAGGAACCATAGAAATGGG
CAGTGGAGGATTCGTCCACACCCACAGCTTCTCAACGGGCCTGAATTTGGCCAAGAAAAACCTTTATGAGCTTGTCCCTCTCTGGTCAAC
TGGTTTTTTGTTCGTTTGTTTTTTGAGACAGGTTTGCCCTTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAACCTC
CACCTCAGGTTCAAGCAATTGTCGTGCCTCAGCCTCCCTAGTAGCTGGGATTACAGGCACCATGCCCAGCTAACTTTTGTATTTTTAGTA
GAGACAGGGTTTCTCCATGTTGGCCAGGCTGGTCTTGAACACCTGGCCTCAAGTGATCTGCCTGTCTTGGCCTCCCAAAGTGCTGGGATT
ACAGGCATGAGCCACCATGCCCAGCAGGTCAACTGTTTTTGCAAGCATTTAGCCAGAGTCATGCTGTGCTGTTAATCAGTGTCCTGGAGA
ATGGGTTGCTTGGAAATCTTGGCGCCCCCTCAGTAGTAACAGCCTTGGTTTAAGGGCGCAGAGTGGAGAGTAAATGCAAGGGCTATAACA
AGGGCATTCATGCTGTGGGTTAAGATCCACAAATCGCTAGGAATGTGTATACTCTGGGTAGTAAGTTTGTAGTATTAGAAGGTTTAATGA
CAAGTATTTGAAGAGCTGAAGTTAAGTGTTGGGAGGCCATCCCTTATGAAGGACAATGAATGGCAAGTAAAAGACCAAGTTCTGTTCCTG
GGTCCATTAATTTAGTTAAAAAGGCAAAGTTCTTTCAGCACACATATCTGCATGCAGTCACGTGCTGCCTAAGGATGCTTCATTCAACAA
TGAGCCTCACAGCCGTGCTACACAATAAGATTATAATACTGTATTTTTACTGTACCTTTTAACATTGTGTTACAATGGCCTACAAGAAGC

>In-frame_ENST00000584450_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=514AA_start in transcript=2_stop in transcript=1546
LRKYKNEVVKLRFPSIGTGETRGAPRAAARPFPRGPLLRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPG
AASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFE
DNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMC
KGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRY
TFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQG

--------------------------------------------------------------
>In-frame_ENST00000269571_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=1794nt_BP=1180nt
GGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAG
CACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGC
CGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCC
AGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACC
AATGCCAGCCTGTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCAG
AGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAATACCACC
CCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGATCCAGCGG
AACCCCCAGCTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGACACCAAC
CGCTCTCGGGCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCTGACGCGC
ACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCC
AAGCACTCTGACTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAACACAGAC
ACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGAC
GTGGGATCCTGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCC
TGTGCCCGAGACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAG
AGAAACGGCAGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTT
GCCTGCAATGGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTC
GTAGAGATTGGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGC
TTTTAACTTGGACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTC
AAGCAATAGGCGCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACT

>In-frame_ENST00000269571_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=485AA_start in transcript=57_stop in transcript=1514
MRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVV
QGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLT
EILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCC
HEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAED
GTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQ

--------------------------------------------------------------
>In-frame_ENST00000269571_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=3333nt_BP=1180nt
GGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCACCCCTCGCAG
CACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGC
CGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCC
AGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACC
AATGCCAGCCTGTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCAG
AGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAATACCACC
CCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGATCCAGCGG
AACCCCCAGCTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGACACCAAC
CGCTCTCGGGCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCTGACGCGC
ACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCC
AAGCACTCTGACTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAACACAGAC
ACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGAC
GTGGGATCCTGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCC
TGTGCCCGAGACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAATTCAACAG
AGAAACGGCAGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAAAAAGTTT
GCCTGCAATGGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCAGTTCCTC
GTAGAGATTGGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTTAAGTGCTTGTGGCTCACTGAAGCTTAAGTGAGGATTTCCTT
GCAATGAGTAGAATTTCCCTTCTCTCCCTTGTCACAGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGCTTTTAAC
TTGGACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTCAAGCAAT
AGGCGCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACTATGGCCG
GAACCTCCTCAGCTCTCCCTCTGCAGAGTTCCCTACCCTAAGAGAATGTTACCACCTGAACAGTCCTCGGTGAATCTGAGAGGAGAGGAT
GGGGTAAGGCAGAAGCACCAGCTGTACTACTAGAAGGGAGCTTTTGGTGGTAGATCCCCTGGTGTCTCCAACCTGACTAGGTGGACAGAG
CTCAAAGAGGCCCTCTTACCGCTAGCGAGGTGATAGGACATCTGGCTTGCCACAAAGGTCTGTTCGACCAGACATATCCTAGCTAAGGGA
TGTCCAAACATCAGAATGTGAGGCCAACCTTCTATCAGAGTTAAACTTTTGACAAGGGAACAAATCTCAAACTGATCCATCAGTCATGTA
GCTAGCTGTAGAGCTTGCAACTTAATAGCAGCAGCTGCCCAATGCCATGTGAAGTAACAAACTGGTTTTTGGTTTTTTTTTCCCCTTCAG
TTTTAATGTTATGTGTAATGTATTTAAACCCTTATTTAAATAAAACTTGTTTTCAGAAATACCTGACTTGCAGATTATTTATATATAGTC
GATCTTGTGCATATAAAGGAACCATAGAAATGGGCAGTGGAGGATTCGTCCACACCCACAGCTTCTCAACGGGCCTGAATTTGGCCAAGA
AAAACCTTTATGAGCTTGTCCCTCTCTGGTCAACTGGTTTTTTGTTCGTTTGTTTTTTGAGACAGGTTTGCCCTTGTTGCCCAGGCTGGA
GTGCAGTGGCACAATCTCGGCTCACTGCAACCTCCACCTCAGGTTCAAGCAATTGTCGTGCCTCAGCCTCCCTAGTAGCTGGGATTACAG
GCACCATGCCCAGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGCCAGGCTGGTCTTGAACACCTGGCCTCAAGTGA
TCTGCCTGTCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCCAGCAGGTCAACTGTTTTTGCAAGCATTTAGCCAG
AGTCATGCTGTGCTGTTAATCAGTGTCCTGGAGAATGGGTTGCTTGGAAATCTTGGCGCCCCCTCAGTAGTAACAGCCTTGGTTTAAGGG
CGCAGAGTGGAGAGTAAATGCAAGGGCTATAACAAGGGCATTCATGCTGTGGGTTAAGATCCACAAATCGCTAGGAATGTGTATACTCTG
GGTAGTAAGTTTGTAGTATTAGAAGGTTTAATGACAAGTATTTGAAGAGCTGAAGTTAAGTGTTGGGAGGCCATCCCTTATGAAGGACAA
TGAATGGCAAGTAAAAGACCAAGTTCTGTTCCTGGGTCCATTAATTTAGTTAAAAAGGCAAAGTTCTTTCAGCACACATATCTGCATGCA
GTCACGTGCTGCCTAAGGATGCTTCATTCAACAATGAGCCTCACAGCCGTGCTACACAATAAGATTATAATACTGTATTTTTACTGTACC
TTTTAACATTGTGTTACAATGGCCTACAAGAAGCTTGTGTGGATGGCTTTGAATGTGGCCCAACACGAACTAATAAATTTTGCTAAAACA

>In-frame_ENST00000269571_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=477AA_start in transcript=57_stop in transcript=1490
MRRAPGPHPSQHPAPRALPAGSSRSHGAGAAVSTMELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVV
QGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLT
EILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCC
HEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAED
GTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQ

--------------------------------------------------------------
>In-frame_ENST00000578199_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=2086nt_BP=1472nt
GTCCACACAGTTTAAATTAAAGTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATA
GGGTTAAGGGAAGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGTCGCAATTGAAGTACCACCT
CCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCCAGCACAGAATTTGGCTTATGCCTAC
TCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTGGCAAAGCAAAGCTATATTCAAGACCAC
ATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCCAGGACAAACGCAGTGCAGCACAGAGACTC
AGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTGTTGTGGACATGCACAAAAGTGAGTGTGCACCGGCACAGA
CATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCT
GGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCA
AGTGAGGCAGGTCCCACTGCAGAGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGG
AGACCCGCTGAACAATACCACCCCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAA
AGGAGGGGTCTTGATCCAGCGGAACCCCCAGCTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGC
TCTCACACTGATAGACACCAACCGCTCTCGGGCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGA
GGATTGTCAGAGCCTGACGCGCACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTG
TGCTGCCGGCTGCACGGGCCCCAAGCACTCTGACTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGC
CCTGGTCACCTACAACACAGACACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCC
CTACAACTACCTTTCTACGGACGTGGGATCCTGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCG
GTGTGAGAAGTGCAGCAAGCCCTGTGCCCGAGACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTA
TATCCATATAAGAATTCAACAGAGAAACGGCAGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGT
GAAGGCGTTTAAGAAAAAGTTTGCCTGCAATGGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACG
CAAGAACATATGCCAGTTCCTCGTAGAGATTGGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTAAAAACCTCACAGCTTGTAT
AATGTAACCATTTGGGGTCCGCTTTTAACTTGGACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAA
GTCCCTCATTTAAACAGAGGTCAAGCAATAGGCGCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAG
AGCCCTAAGATTACAAACAACTATGGCCGGAACCTCCTCAGCTCTCCCTCTGCAGAGTTCCCTACCCTAAGAGAATGTTACCACCTGAAC

>In-frame_ENST00000578199_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=421AA_start in transcript=541_stop in transcript=1806
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE
DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLV

--------------------------------------------------------------
>In-frame_ENST00000578199_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=3625nt_BP=1472nt
GTCCACACAGTTTAAATTAAAGTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATA
GGGTTAAGGGAAGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGTCGCAATTGAAGTACCACCT
CCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCCAGCACAGAATTTGGCTTATGCCTAC
TCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTGGCAAAGCAAAGCTATATTCAAGACCAC
ATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCCAGGACAAACGCAGTGCAGCACAGAGACTC
AGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTGTTGTGGACATGCACAAAAGTGAGTGTGCACCGGCACAGA
CATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCT
GGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCA
AGTGAGGCAGGTCCCACTGCAGAGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGG
AGACCCGCTGAACAATACCACCCCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAA
AGGAGGGGTCTTGATCCAGCGGAACCCCCAGCTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGC
TCTCACACTGATAGACACCAACCGCTCTCGGGCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGA
GGATTGTCAGAGCCTGACGCGCACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTG
TGCTGCCGGCTGCACGGGCCCCAAGCACTCTGACTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGC
CCTGGTCACCTACAACACAGACACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCC
CTACAACTACCTTTCTACGGACGTGGGATCCTGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCG
GTGTGAGAAGTGCAGCAAGCCCTGTGCCCGAGACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTA
TATCCATATAAGAATTCAACAGAGAAACGGCAGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGT
GAAGGCGTTTAAGAAAAAGTTTGCCTGCAATGGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACG
CAAGAACATATGCCAGTTCCTCGTAGAGATTGGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTTAAGTGCTTGTGGCTCACTG
AAGCTTAAGTGAGGATTTCCTTGCAATGAGTAGAATTTCCCTTCTCTCCCTTGTCACAGGTTTAAAAACCTCACAGCTTGTATAATGTAA
CCATTTGGGGTCCGCTTTTAACTTGGACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTC
ATTTAAACAGAGGTCAAGCAATAGGCGCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTA
AGATTACAAACAACTATGGCCGGAACCTCCTCAGCTCTCCCTCTGCAGAGTTCCCTACCCTAAGAGAATGTTACCACCTGAACAGTCCTC
GGTGAATCTGAGAGGAGAGGATGGGGTAAGGCAGAAGCACCAGCTGTACTACTAGAAGGGAGCTTTTGGTGGTAGATCCCCTGGTGTCTC
CAACCTGACTAGGTGGACAGAGCTCAAAGAGGCCCTCTTACCGCTAGCGAGGTGATAGGACATCTGGCTTGCCACAAAGGTCTGTTCGAC
CAGACATATCCTAGCTAAGGGATGTCCAAACATCAGAATGTGAGGCCAACCTTCTATCAGAGTTAAACTTTTGACAAGGGAACAAATCTC
AAACTGATCCATCAGTCATGTAGCTAGCTGTAGAGCTTGCAACTTAATAGCAGCAGCTGCCCAATGCCATGTGAAGTAACAAACTGGTTT
TTGGTTTTTTTTTCCCCTTCAGTTTTAATGTTATGTGTAATGTATTTAAACCCTTATTTAAATAAAACTTGTTTTCAGAAATACCTGACT
TGCAGATTATTTATATATAGTCGATCTTGTGCATATAAAGGAACCATAGAAATGGGCAGTGGAGGATTCGTCCACACCCACAGCTTCTCA
ACGGGCCTGAATTTGGCCAAGAAAAACCTTTATGAGCTTGTCCCTCTCTGGTCAACTGGTTTTTTGTTCGTTTGTTTTTTGAGACAGGTT
TGCCCTTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAACCTCCACCTCAGGTTCAAGCAATTGTCGTGCCTCAGCC
TCCCTAGTAGCTGGGATTACAGGCACCATGCCCAGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGCCAGGCTGGTC
TTGAACACCTGGCCTCAAGTGATCTGCCTGTCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCCAGCAGGTCAACT
GTTTTTGCAAGCATTTAGCCAGAGTCATGCTGTGCTGTTAATCAGTGTCCTGGAGAATGGGTTGCTTGGAAATCTTGGCGCCCCCTCAGT
AGTAACAGCCTTGGTTTAAGGGCGCAGAGTGGAGAGTAAATGCAAGGGCTATAACAAGGGCATTCATGCTGTGGGTTAAGATCCACAAAT
CGCTAGGAATGTGTATACTCTGGGTAGTAAGTTTGTAGTATTAGAAGGTTTAATGACAAGTATTTGAAGAGCTGAAGTTAAGTGTTGGGA
GGCCATCCCTTATGAAGGACAATGAATGGCAAGTAAAAGACCAAGTTCTGTTCCTGGGTCCATTAATTTAGTTAAAAAGGCAAAGTTCTT
TCAGCACACATATCTGCATGCAGTCACGTGCTGCCTAAGGATGCTTCATTCAACAATGAGCCTCACAGCCGTGCTACACAATAAGATTAT
AATACTGTATTTTTACTGTACCTTTTAACATTGTGTTACAATGGCCTACAAGAAGCTTGTGTGGATGGCTTTGAATGTGGCCCAACACGA

>In-frame_ENST00000578199_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=413AA_start in transcript=541_stop in transcript=1782
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE
DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLV

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>In-frame_ENST00000540042_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=1711nt_BP=1097nt
GAATGCACAGGGTGGGCCTAGTCAGAAGAAGCCTTTCCCCTGAAATCCCTCTACTTCCCAAGCACGCAAGCTTTCTCCTGCTGTTAAACC
TGCAGTGTGCAAGGGACATGGGCGGAGGGGTCCTTCAGTCAGGCTTCTCCCTGTCTGAGTGTGCACCGGCACAGACATGAAGCTGCGGCT
CCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCT
GCCCACCAATGCCAGCCTGTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCC
ACTGCAGAGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAA
TACCACCCCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGAT
CCAGCGGAACCCCCAGCTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGA
CACCAACCGCTCTCGGGCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCT
GACGCGCACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCAC
GGGCCCCAAGCACTCTGACTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAA
CACAGACACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTC
TACGGACGTGGGATCCTGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAG
CAAGCCCTGTGCCCGAGACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAAT
TCAACAGAGAAACGGCAGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAA
AAAGTTTGCCTGCAATGGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCA
GTTCCTCGTAGAGATTGGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGG
GGTCCGCTTTTAACTTGGACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAAC
AGAGGTCAAGCAATAGGCGCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACA
AACAACTATGGCCGGAACCTCCTCAGCTCTCCCTCTGCAGAGTTCCCTACCCTAAGAGAATGTTACCACCTGAACAGTCCTCGGTGAATC

>In-frame_ENST00000540042_ENST00000591776_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=421AA_start in transcript=166_stop in transcript=1431
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE
DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLV

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>In-frame_ENST00000540042_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(transcript)=3250nt_BP=1097nt
GAATGCACAGGGTGGGCCTAGTCAGAAGAAGCCTTTCCCCTGAAATCCCTCTACTTCCCAAGCACGCAAGCTTTCTCCTGCTGTTAAACC
TGCAGTGTGCAAGGGACATGGGCGGAGGGGTCCTTCAGTCAGGCTTCTCCCTGTCTGAGTGTGCACCGGCACAGACATGAAGCTGCGGCT
CCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCT
GCCCACCAATGCCAGCCTGTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCC
ACTGCAGAGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAA
TACCACCCCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGAT
CCAGCGGAACCCCCAGCTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGA
CACCAACCGCTCTCGGGCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCT
GACGCGCACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCAC
GGGCCCCAAGCACTCTGACTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAA
CACAGACACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTC
TACGGACGTGGGATCCTGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAG
CAAGCCCTGTGCCCGAGACCCCTTTGCTGATGCAAGTAAGGGTGATGACCTGCTTCCTGCTGGCACTGAGGATTATATCCATATAAGAAT
TCAACAGAGAAACGGCAGGAAGACCCTTACTACTGTCCAAGGGATCGCTGATGATTACGATAAAAAGAAACTAGTGAAGGCGTTTAAGAA
AAAGTTTGCCTGCAATGGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGGTGACCAACGCAAGAACATATGCCA
GTTCCTCGTAGAGATTGGACTGGCTAAGGACGATCAGCTGAAGGTTCATGGGTTTTAAGTGCTTGTGGCTCACTGAAGCTTAAGTGAGGA
TTTCCTTGCAATGAGTAGAATTTCCCTTCTCTCCCTTGTCACAGGTTTAAAAACCTCACAGCTTGTATAATGTAACCATTTGGGGTCCGC
TTTTAACTTGGACTAGTGTAACTCCTTCATGCAATAAACTGAAAAGAGCCATGCTGTCTAGTCTTGAAGTCCCTCATTTAAACAGAGGTC
AAGCAATAGGCGCCTGGCAGTGTCAAGCCTGAAACCAAGCAATACCGTCATGTTTCAGCCAAGCCCAGAGCCCTAAGATTACAAACAACT
ATGGCCGGAACCTCCTCAGCTCTCCCTCTGCAGAGTTCCCTACCCTAAGAGAATGTTACCACCTGAACAGTCCTCGGTGAATCTGAGAGG
AGAGGATGGGGTAAGGCAGAAGCACCAGCTGTACTACTAGAAGGGAGCTTTTGGTGGTAGATCCCCTGGTGTCTCCAACCTGACTAGGTG
GACAGAGCTCAAAGAGGCCCTCTTACCGCTAGCGAGGTGATAGGACATCTGGCTTGCCACAAAGGTCTGTTCGACCAGACATATCCTAGC
TAAGGGATGTCCAAACATCAGAATGTGAGGCCAACCTTCTATCAGAGTTAAACTTTTGACAAGGGAACAAATCTCAAACTGATCCATCAG
TCATGTAGCTAGCTGTAGAGCTTGCAACTTAATAGCAGCAGCTGCCCAATGCCATGTGAAGTAACAAACTGGTTTTTGGTTTTTTTTTCC
CCTTCAGTTTTAATGTTATGTGTAATGTATTTAAACCCTTATTTAAATAAAACTTGTTTTCAGAAATACCTGACTTGCAGATTATTTATA
TATAGTCGATCTTGTGCATATAAAGGAACCATAGAAATGGGCAGTGGAGGATTCGTCCACACCCACAGCTTCTCAACGGGCCTGAATTTG
GCCAAGAAAAACCTTTATGAGCTTGTCCCTCTCTGGTCAACTGGTTTTTTGTTCGTTTGTTTTTTGAGACAGGTTTGCCCTTGTTGCCCA
GGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAACCTCCACCTCAGGTTCAAGCAATTGTCGTGCCTCAGCCTCCCTAGTAGCTGGG
ATTACAGGCACCATGCCCAGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGCCAGGCTGGTCTTGAACACCTGGCCT
CAAGTGATCTGCCTGTCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCCAGCAGGTCAACTGTTTTTGCAAGCATT
TAGCCAGAGTCATGCTGTGCTGTTAATCAGTGTCCTGGAGAATGGGTTGCTTGGAAATCTTGGCGCCCCCTCAGTAGTAACAGCCTTGGT
TTAAGGGCGCAGAGTGGAGAGTAAATGCAAGGGCTATAACAAGGGCATTCATGCTGTGGGTTAAGATCCACAAATCGCTAGGAATGTGTA
TACTCTGGGTAGTAAGTTTGTAGTATTAGAAGGTTTAATGACAAGTATTTGAAGAGCTGAAGTTAAGTGTTGGGAGGCCATCCCTTATGA
AGGACAATGAATGGCAAGTAAAAGACCAAGTTCTGTTCCTGGGTCCATTAATTTAGTTAAAAAGGCAAAGTTCTTTCAGCACACATATCT
GCATGCAGTCACGTGCTGCCTAAGGATGCTTCATTCAACAATGAGCCTCACAGCCGTGCTACACAATAAGATTATAATACTGTATTTTTA
CTGTACCTTTTAACATTGTGTTACAATGGCCTACAAGAAGCTTGTGTGGATGGCTTTGAATGTGGCCCAACACGAACTAATAAATTTTGC

>In-frame_ENST00000540042_ENST00000469257_TCGA-BR-A4PE_ERBB2_chr17_37868300_+_EIF1_chr17_39846029_length(amino acids)=413AA_start in transcript=166_stop in transcript=1407
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE
DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLV

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Fusion Gene PPI Analysis for ERBB2-EIF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneERBB2chr17:37868300chr17:39846029ENST00000269571+8271195_1197340.33333333333331256.0PIK3C2B
HgeneERBB2chr17:37868300chr17:39846029ENST00000541774+8271195_1197325.33333333333331241.0PIK3C2B


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ERBB2-EIF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneERBB2P04626DB06366PertuzumabInhibitorBiotechApproved
HgeneERBB2P04626DB06366PertuzumabInhibitorBiotechApproved
HgeneERBB2P04626DB06366PertuzumabInhibitorBiotechApproved
HgeneERBB2P04626DB06366PertuzumabInhibitorBiotechApproved
HgeneERBB2P04626DB06366PertuzumabInhibitorBiotechApproved
HgeneERBB2P04626DB08916AfatinibInhibitorSmall moleculeApproved
HgeneERBB2P04626DB08916AfatinibInhibitorSmall moleculeApproved
HgeneERBB2P04626DB08916AfatinibInhibitorSmall moleculeApproved
HgeneERBB2P04626DB08916AfatinibInhibitorSmall moleculeApproved
HgeneERBB2P04626DB08916AfatinibInhibitorSmall moleculeApproved
HgeneERBB2P04626DB00072TrastuzumabAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB00072TrastuzumabAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB00072TrastuzumabAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB00072TrastuzumabAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB00072TrastuzumabAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB01259LapatinibAntagonistSmall moleculeApproved|Investigational
HgeneERBB2P04626DB01259LapatinibAntagonistSmall moleculeApproved|Investigational
HgeneERBB2P04626DB01259LapatinibAntagonistSmall moleculeApproved|Investigational
HgeneERBB2P04626DB01259LapatinibAntagonistSmall moleculeApproved|Investigational
HgeneERBB2P04626DB01259LapatinibAntagonistSmall moleculeApproved|Investigational
HgeneERBB2P04626DB05773Trastuzumab emtansineAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB05773Trastuzumab emtansineAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB05773Trastuzumab emtansineAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB05773Trastuzumab emtansineAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB05773Trastuzumab emtansineAntibodyBiotechApproved|Investigational
HgeneERBB2P04626DB11652TucatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB11652TucatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB11652TucatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB11652TucatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB11652TucatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB15035ZanubrutinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB15035ZanubrutinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB15035ZanubrutinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB15035ZanubrutinibInhibitorSmall moleculeApproved|Investigational
HgeneERBB2P04626DB15035ZanubrutinibInhibitorSmall moleculeApproved|Investigational

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Related Diseases for ERBB2-EIF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneERBB2C0006142Malignant neoplasm of breast40CGI;CTD_human
HgeneERBB2C0678222Breast Carcinoma40CGI;CTD_human
HgeneERBB2C1257931Mammary Neoplasms, Human40CTD_human
HgeneERBB2C1458155Mammary Neoplasms40CTD_human
HgeneERBB2C4704874Mammary Carcinoma, Human40CTD_human
HgeneERBB2C1140680Malignant neoplasm of ovary4CGI;CTD_human;UNIPROT
HgeneERBB2C0024623Malignant neoplasm of stomach3CGI;CTD_human
HgeneERBB2C0033578Prostatic Neoplasms3CTD_human
HgeneERBB2C0038356Stomach Neoplasms3CGI;CTD_human
HgeneERBB2C0235874Disease Exacerbation3CTD_human
HgeneERBB2C0376358Malignant neoplasm of prostate3CTD_human
HgeneERBB2C1708349Hereditary Diffuse Gastric Cancer3CTD_human
HgeneERBB2C0001418Adenocarcinoma2CTD_human
HgeneERBB2C0024668Mammary Neoplasms, Experimental2CTD_human
HgeneERBB2C0205641Adenocarcinoma, Basal Cell2CTD_human
HgeneERBB2C0205642Adenocarcinoma, Oxyphilic2CTD_human
HgeneERBB2C0205643Carcinoma, Cribriform2CTD_human
HgeneERBB2C0205644Carcinoma, Granular Cell2CTD_human
HgeneERBB2C0205645Adenocarcinoma, Tubular2CTD_human
HgeneERBB2C0699791Stomach Carcinoma2CGI;UNIPROT
HgeneERBB2C0919267ovarian neoplasm2CGI;CTD_human
HgeneERBB2C0007102Malignant tumor of colon1CTD_human
HgeneERBB2C0007134Renal Cell Carcinoma1CTD_human
HgeneERBB2C0009375Colonic Neoplasms1CTD_human
HgeneERBB2C0013930Embolism, Tumor1CTD_human
HgeneERBB2C0014859Esophageal Neoplasms1CTD_human
HgeneERBB2C0016978gallbladder neoplasm1CTD_human
HgeneERBB2C0017185Gastrointestinal Neoplasms1CTD_human
HgeneERBB2C0021367Mammary Ductal Carcinoma1CTD_human
HgeneERBB2C0024121Lung Neoplasms1CTD_human
HgeneERBB2C0024232Lymphatic Metastasis1CTD_human
HgeneERBB2C0024667Animal Mammary Neoplasms1CTD_human
HgeneERBB2C0025149Medulloblastoma1CTD_human
HgeneERBB2C0027627Neoplasm Metastasis1CTD_human
HgeneERBB2C0027643Neoplasm Recurrence, Local1CTD_human
HgeneERBB2C0027659Neoplasms, Experimental1CTD_human
HgeneERBB2C0030354Papilloma1CTD_human
HgeneERBB2C0153452Malignant neoplasm of gallbladder1CTD_human
HgeneERBB2C0205833Medullomyoblastoma1CTD_human
HgeneERBB2C0205874Papilloma, Squamous Cell1CTD_human
HgeneERBB2C0205875Papillomatosis1CTD_human
HgeneERBB2C0206698Cholangiocarcinoma1CTD_human
HgeneERBB2C0242379Malignant neoplasm of lung1CTD_human
HgeneERBB2C0278510Childhood Medulloblastoma1CTD_human
HgeneERBB2C0278876Adult Medulloblastoma1CTD_human
HgeneERBB2C0279702Conventional (Clear Cell) Renal Cell Carcinoma1CTD_human
HgeneERBB2C0345905Intrahepatic Cholangiocarcinoma1CTD_human
HgeneERBB2C0546837Malignant neoplasm of esophagus1CTD_human
HgeneERBB2C0596263Carcinogenesis1CTD_human
HgeneERBB2C0684249Carcinoma of lung1UNIPROT
HgeneERBB2C0685938Malignant neoplasm of gastrointestinal tract1CTD_human
HgeneERBB2C0751291Desmoplastic Medulloblastoma1CTD_human
HgeneERBB2C1134719Invasive Ductal Breast Carcinoma1CTD_human
HgeneERBB2C1257925Mammary Carcinoma, Animal1CTD_human
HgeneERBB2C1266042Chromophobe Renal Cell Carcinoma1CTD_human
HgeneERBB2C1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
HgeneERBB2C1266044Collecting Duct Carcinoma of the Kidney1CTD_human
HgeneERBB2C1275668Melanotic medulloblastoma1CTD_human
HgeneERBB2C1306837Papillary Renal Cell Carcinoma1CTD_human
HgeneERBB2C1368275Pigmented Basal Cell Carcinoma1CTD_human
HgeneERBB2C2750850GLIOMA SUSCEPTIBILITY 11UNIPROT
HgeneERBB2C2931822Nasopharyngeal carcinoma1CTD_human
HgeneERBB2C3805278Extrahepatic Cholangiocarcinoma1CTD_human
HgeneERBB2C4721610Carcinoma, Ovarian Epithelial1CTD_human
HgeneERBB2C4721806Carcinoma, Basal Cell1CTD_human