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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ERBB2-PPP1R1B (FusionGDB2 ID:27134)

Fusion Gene Summary for ERBB2-PPP1R1B

Fusion gene summary

Fusion gene information	Fusion gene name: ERBB2-PPP1R1B
	Fusion gene ID: 27134
		Hgene	Tgene
	Gene symbol	ERBB2	PPP1R1B
	Gene ID	2064	84152
	Gene name	erb-b2 receptor tyrosine kinase 2	protein phosphatase 1 regulatory inhibitor subunit 1B
	Synonyms	CD340\|HER-2\|HER-2/neu\|HER2\|MLN 19\|NEU\|NGL\|TKR1	DARPP-32\|DARPP32
	Cytomap	17q12	17q12
	Type of gene	protein-coding	protein-coding
	Description	receptor tyrosine-protein kinase erbB-2c-erb B2/neu proteinherstatinhuman epidermal growth factor receptor 2metastatic lymph node gene 19 proteinneuro/glioblastoma derived oncogene homologneuroblastoma/glioblastoma derived oncogene homologp185erbB2	protein phosphatase 1 regulatory subunit 1Bdopamine and cAMP-regulated neuronal phosphoprotein 32
	Modification date	20200329	20200313
	UniProtAcc	P04626	.
	Ensembl transtripts involved in fusion gene	ENST00000584601, ENST00000406381, ENST00000541774, ENST00000445658, ENST00000540147, ENST00000584450, ENST00000269571, ENST00000578199, ENST00000540042, ENST00000584888,	ENST00000580825, ENST00000254079, ENST00000579000, ENST00000394265, ENST00000394267,
Fusion gene scores	* DoF score	50 X 44 X 14=30800	17 X 10 X 9=1530
	# samples	73	26
	** MAII score	log2(73/30800*10)=-5.39889007670225 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(26/1530*10)=-2.55694812455156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: ERBB2 [Title/Abstract] AND PPP1R1B [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ERBB2(37883800)-PPP1R1B(37791860), # samples:9 PPP1R1B(37783927)-ERBB2(37879912), # samples:1 PPP1R1B(37783962)-ERBB2(37879912), # samples:1
Anticipated loss of major functional domain due to fusion event.	ERBB2-PPP1R1B seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF. ERBB2-PPP1R1B seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. ERBB2-PPP1R1B seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. ERBB2-PPP1R1B seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	ERBB2	GO:0007165	signal transduction	10572067
Hgene	ERBB2	GO:0007166	cell surface receptor signaling pathway	9685399
Hgene	ERBB2	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	7514177
Hgene	ERBB2	GO:0014065	phosphatidylinositol 3-kinase signaling	7556068
Hgene	ERBB2	GO:0018108	peptidyl-tyrosine phosphorylation	12000754
Hgene	ERBB2	GO:0032886	regulation of microtubule-based process	20937854
Hgene	ERBB2	GO:0035556	intracellular signal transduction	19372587
Hgene	ERBB2	GO:0042060	wound healing	12646923
Hgene	ERBB2	GO:0043406	positive regulation of MAP kinase activity	10572067
Hgene	ERBB2	GO:0045785	positive regulation of cell adhesion	7556068
Hgene	ERBB2	GO:0046777	protein autophosphorylation	7556068
Hgene	ERBB2	GO:0050679	positive regulation of epithelial cell proliferation	10572067
Hgene	ERBB2	GO:0071363	cellular response to growth factor stimulus	20010870
Hgene	ERBB2	GO:0090314	positive regulation of protein targeting to membrane	20010870
Tgene	PPP1R1B	GO:0032515	negative regulation of phosphoprotein phosphatase activity	10807923

Fusion gene breakpoints across ERBB2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PPP1R1B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-DK-A1A3-01A	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
ChimerDB4	BRCA	TCGA-C8-A12Z-01A	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
ChimerDB4	BRCA	TCGA-UU-A93S-01A	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
ChimerDB4	CESC	TCGA-4J-AA1J-01A	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
ChimerDB4	CESC	TCGA-Q1-A73R-01A	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
ChimerDB4	ESCA	TCGA-2H-A9GF-01A	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
ChimerDB4	LIHC	TCGA-KR-A7K2-01A	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
ChimerDB4	LUSC	TCGA-22-0944-01A	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
ChimerDB4	OV	TCGA-24-2033-01A	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
ChimerDB4	PAAD	TCGA-LB-A7SX-01A	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
ChimerDB4	CESC	TCGA-Q1-A73R	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
ChimerDB4	CESC	TCGA-Q1-A73R	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
ChimerDB4	PAAD	TCGA-LB-A7SX	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
ChimerDB4	BLCA	TCGA-DK-A1A3-01A	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
ChimerDB4	CESC	TCGA-Q1-A73R-01A	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
ChimerDB4	CESC	TCGA-Q1-A73R-01A	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
ChimerDB4	LIHC	TCGA-KR-A7K2-01A	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
ChimerDB4	LUSC	TCGA-22-0944	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
ChimerDB4	PAAD	TCGA-LB-A7SX	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
ChimerDB4	STAD	TCGA-RD-A7BT-01A	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
ChimerDB4	BLCA	TCGA-DK-A1A3-01A	ERBB2	chr17	37866734	-	PPP1R1B	chr17	37790136	+
ChimerDB4	LIHC	TCGA-KR-A7K2-01A	ERBB2	chr17	37883800	-	PPP1R1B	chr17	37791860	+
ChimerDB4	PAAD	TCGA-LB-A7SX-01A	ERBB2	chr17	37883800	-	PPP1R1B	chr17	37791860	+
ChimerDB4	CESC	TCGA-Q1-A73R-01A	ERBB2	chr17	37883800	-	PPP1R1B	chr17	37791860	+
ChimerDB4	CESC	TCGA-Q1-A73R-01A	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
ChimerDB4	CESC	TCGA-Q1-A73R-01A	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+

Top

Fusion Gene ORF analysis for ERBB2-PPP1R1B

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000584601	ENST00000580825	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584601	ENST00000254079	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584601	ENST00000579000	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584601	ENST00000394265	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584601	ENST00000394267	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000406381	ENST00000580825	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000406381	ENST00000254079	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000406381	ENST00000579000	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000406381	ENST00000394265	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000406381	ENST00000394267	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000541774	ENST00000580825	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000541774	ENST00000254079	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000541774	ENST00000579000	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000541774	ENST00000394265	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000541774	ENST00000394267	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000445658	ENST00000580825	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000445658	ENST00000254079	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000445658	ENST00000579000	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000445658	ENST00000394265	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000445658	ENST00000394267	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540147	ENST00000580825	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540147	ENST00000254079	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540147	ENST00000579000	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540147	ENST00000394265	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540147	ENST00000394267	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000580825	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000254079	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000579000	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000394265	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000394267	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000580825	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000254079	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000579000	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000394265	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000394267	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000578199	ENST00000580825	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000578199	ENST00000254079	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000578199	ENST00000579000	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000578199	ENST00000394265	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000578199	ENST00000394267	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540042	ENST00000580825	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540042	ENST00000254079	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540042	ENST00000579000	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540042	ENST00000394265	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540042	ENST00000394267	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000580825	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000254079	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000579000	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000394265	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000394267	ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584601	ENST00000580825	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584601	ENST00000254079	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584601	ENST00000579000	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584601	ENST00000394265	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584601	ENST00000394267	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000406381	ENST00000580825	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000406381	ENST00000254079	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000406381	ENST00000579000	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000406381	ENST00000394265	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000406381	ENST00000394267	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000541774	ENST00000580825	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000541774	ENST00000254079	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000541774	ENST00000579000	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000541774	ENST00000394265	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000541774	ENST00000394267	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000445658	ENST00000580825	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000445658	ENST00000254079	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000445658	ENST00000579000	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000445658	ENST00000394265	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000445658	ENST00000394267	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540147	ENST00000580825	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540147	ENST00000254079	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540147	ENST00000579000	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540147	ENST00000394265	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540147	ENST00000394267	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000580825	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000254079	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000579000	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000394265	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000394267	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000580825	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000254079	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000579000	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000394265	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000394267	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000578199	ENST00000580825	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000578199	ENST00000254079	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000578199	ENST00000579000	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000578199	ENST00000394265	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000578199	ENST00000394267	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540042	ENST00000580825	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540042	ENST00000254079	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540042	ENST00000579000	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540042	ENST00000394265	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000540042	ENST00000394267	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000580825	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000254079	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000579000	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000394265	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000394267	ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584601	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584601	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584601	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584601	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584601	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000406381	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000406381	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000406381	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000406381	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000406381	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000541774	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000541774	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000541774	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000541774	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000541774	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000445658	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000445658	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000445658	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000445658	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000445658	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
5UTR-3CDS	ENST00000540147	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
5UTR-3CDS	ENST00000540147	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
5UTR-3CDS	ENST00000540147	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
5UTR-3CDS	ENST00000540147	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
5UTR-3CDS	ENST00000540147	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584450	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000269571	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000578199	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000578199	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000578199	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000578199	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000578199	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000540042	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000540042	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000540042	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000540042	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000540042	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
intron-3CDS	ENST00000584888	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790136	+
In-frame	ENST00000584601	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000584601	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000584601	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000584601	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000584601	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000406381	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000406381	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000406381	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000406381	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000406381	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000541774	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000541774	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000541774	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000541774	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000541774	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000445658	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000445658	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000445658	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000445658	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000445658	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000540147	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000540147	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000540147	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000540147	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000540147	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584450	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584450	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584450	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584450	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584450	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000269571	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000269571	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000269571	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000269571	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
In-frame	ENST00000269571	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000578199	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000578199	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000578199	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000578199	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000578199	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000540042	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000540042	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000540042	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000540042	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000540042	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584888	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584888	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584888	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584888	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584888	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000584601	ENST00000580825	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000584601	ENST00000254079	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000584601	ENST00000579000	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000584601	ENST00000394265	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000584601	ENST00000394267	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000406381	ENST00000580825	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000406381	ENST00000254079	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000406381	ENST00000579000	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000406381	ENST00000394265	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000406381	ENST00000394267	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000541774	ENST00000580825	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000541774	ENST00000254079	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000541774	ENST00000579000	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000541774	ENST00000394265	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000541774	ENST00000394267	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000445658	ENST00000580825	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000445658	ENST00000254079	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000445658	ENST00000579000	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000445658	ENST00000394265	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000445658	ENST00000394267	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000540147	ENST00000580825	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000540147	ENST00000254079	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000540147	ENST00000579000	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000540147	ENST00000394265	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000540147	ENST00000394267	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000584450	ENST00000580825	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000584450	ENST00000254079	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000584450	ENST00000579000	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000584450	ENST00000394265	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000584450	ENST00000394267	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000269571	ENST00000580825	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000269571	ENST00000254079	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000269571	ENST00000579000	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
In-frame	ENST00000269571	ENST00000394265	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
Frame-shift	ENST00000269571	ENST00000394267	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000578199	ENST00000580825	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000578199	ENST00000254079	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000578199	ENST00000579000	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000578199	ENST00000394265	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000578199	ENST00000394267	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000540042	ENST00000580825	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000540042	ENST00000254079	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000540042	ENST00000579000	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000540042	ENST00000394265	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000540042	ENST00000394267	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000584888	ENST00000580825	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000584888	ENST00000254079	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000584888	ENST00000579000	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000584888	ENST00000394265	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000584888	ENST00000394267	ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792069	+
intron-3CDS	ENST00000584601	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000584601	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000584601	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000584601	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000584601	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000406381	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000406381	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000406381	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000406381	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000406381	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000541774	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000541774	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000541774	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000541774	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000541774	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
Frame-shift	ENST00000445658	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
Frame-shift	ENST00000445658	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
Frame-shift	ENST00000445658	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
5CDS-5UTR	ENST00000445658	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
5CDS-5UTR	ENST00000445658	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
5UTR-3CDS	ENST00000540147	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
5UTR-3CDS	ENST00000540147	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
5UTR-3CDS	ENST00000540147	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
5UTR-5UTR	ENST00000540147	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
5UTR-5UTR	ENST00000540147	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
Frame-shift	ENST00000584450	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
Frame-shift	ENST00000584450	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
Frame-shift	ENST00000584450	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
5CDS-5UTR	ENST00000584450	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
5CDS-5UTR	ENST00000584450	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
Frame-shift	ENST00000269571	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
Frame-shift	ENST00000269571	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
Frame-shift	ENST00000269571	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
5CDS-5UTR	ENST00000269571	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
5CDS-5UTR	ENST00000269571	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000578199	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000578199	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000578199	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000578199	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000578199	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000540042	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000540042	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000540042	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000540042	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000540042	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000584888	ENST00000580825	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000584888	ENST00000254079	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-3CDS	ENST00000584888	ENST00000579000	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000584888	ENST00000394265	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
intron-5UTR	ENST00000584888	ENST00000394267	ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785423	+
In-frame	ENST00000584601	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000584601	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000584601	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000584601	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000584601	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000406381	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000406381	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000406381	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000406381	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000406381	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000541774	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000541774	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000541774	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000541774	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000541774	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000445658	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000445658	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000445658	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000445658	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000445658	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000540147	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000540147	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000540147	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000540147	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000540147	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584450	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584450	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584450	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584450	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584450	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000269571	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000269571	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000269571	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000269571	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000269571	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000580825	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000254079	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000579000	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000394265	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000394267	ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584601	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584601	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584601	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584601	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584601	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000406381	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000406381	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000406381	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000406381	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000406381	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000541774	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000541774	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000541774	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000541774	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000541774	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000445658	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000445658	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000445658	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000445658	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000445658	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000540147	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000540147	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000540147	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000540147	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000540147	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584450	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584450	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584450	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584450	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584450	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000269571	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000269571	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000269571	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000269571	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000269571	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584601	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000584601	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000584601	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000584601	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000584601	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000406381	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000406381	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000406381	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000406381	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000406381	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000541774	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000541774	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000541774	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000541774	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000541774	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000445658	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000445658	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000445658	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000445658	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000445658	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000540147	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000540147	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000540147	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000540147	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000540147	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000584450	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000584450	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000584450	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000584450	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000584450	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000269571	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000269571	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000269571	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000269571	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
Frame-shift	ENST00000269571	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000578199	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000578199	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000578199	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000578199	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000578199	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000540042	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000540042	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000540042	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000540042	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000540042	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584888	ENST00000580825	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584888	ENST00000254079	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584888	ENST00000579000	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584888	ENST00000394265	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-3CDS	ENST00000584888	ENST00000394267	ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791860	+
intron-5UTR	ENST00000584601	ENST00000580825	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000584601	ENST00000254079	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000584601	ENST00000579000	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000584601	ENST00000394265	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000584601	ENST00000394267	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000406381	ENST00000580825	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000406381	ENST00000254079	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000406381	ENST00000579000	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000406381	ENST00000394265	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000406381	ENST00000394267	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000541774	ENST00000580825	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000541774	ENST00000254079	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000541774	ENST00000579000	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000541774	ENST00000394265	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000541774	ENST00000394267	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000445658	ENST00000580825	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000445658	ENST00000254079	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000445658	ENST00000579000	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000445658	ENST00000394265	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000445658	ENST00000394267	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000540147	ENST00000580825	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000540147	ENST00000254079	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000540147	ENST00000579000	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000540147	ENST00000394265	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000540147	ENST00000394267	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000584450	ENST00000580825	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000584450	ENST00000254079	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000584450	ENST00000579000	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000584450	ENST00000394265	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000584450	ENST00000394267	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000269571	ENST00000580825	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000269571	ENST00000254079	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000269571	ENST00000579000	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000269571	ENST00000394265	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000269571	ENST00000394267	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000578199	ENST00000580825	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000578199	ENST00000254079	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000578199	ENST00000579000	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000578199	ENST00000394265	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000578199	ENST00000394267	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000540042	ENST00000580825	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000540042	ENST00000254079	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-5UTR	ENST00000540042	ENST00000579000	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000540042	ENST00000394265	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
intron-intron	ENST00000540042	ENST00000394267	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
3UTR-5UTR	ENST00000584888	ENST00000580825	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
3UTR-5UTR	ENST00000584888	ENST00000254079	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
3UTR-5UTR	ENST00000584888	ENST00000579000	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
3UTR-intron	ENST00000584888	ENST00000394265	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
3UTR-intron	ENST00000584888	ENST00000394267	ERBB2	chr17	37886516	+	PPP1R1B	chr17	37783559	+
Frame-shift	ENST00000584601	ENST00000580825	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584601	ENST00000254079	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584601	ENST00000579000	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584601	ENST00000394265	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584601	ENST00000394267	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000406381	ENST00000580825	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000406381	ENST00000254079	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000406381	ENST00000579000	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000406381	ENST00000394265	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000406381	ENST00000394267	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000541774	ENST00000580825	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000541774	ENST00000254079	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000541774	ENST00000579000	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000541774	ENST00000394265	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000541774	ENST00000394267	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000445658	ENST00000580825	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000445658	ENST00000254079	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000445658	ENST00000579000	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000445658	ENST00000394265	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000445658	ENST00000394267	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000540147	ENST00000580825	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000540147	ENST00000254079	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000540147	ENST00000579000	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000540147	ENST00000394265	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000540147	ENST00000394267	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584450	ENST00000580825	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584450	ENST00000254079	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584450	ENST00000579000	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584450	ENST00000394265	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000584450	ENST00000394267	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000269571	ENST00000580825	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000269571	ENST00000254079	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000269571	ENST00000579000	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000269571	ENST00000394265	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
Frame-shift	ENST00000269571	ENST00000394267	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000580825	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000254079	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000579000	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000394265	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000394267	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000580825	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000254079	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000579000	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000394265	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000394267	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000580825	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000254079	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000579000	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000394265	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000394267	ERBB2	chr17	37883255	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000584601	ENST00000580825	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000584601	ENST00000254079	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000584601	ENST00000579000	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000584601	ENST00000394265	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000584601	ENST00000394267	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000406381	ENST00000580825	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000406381	ENST00000254079	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000406381	ENST00000579000	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000406381	ENST00000394265	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000406381	ENST00000394267	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000541774	ENST00000580825	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000541774	ENST00000254079	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000541774	ENST00000579000	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000541774	ENST00000394265	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000541774	ENST00000394267	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000445658	ENST00000580825	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000445658	ENST00000254079	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000445658	ENST00000579000	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000445658	ENST00000394265	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000445658	ENST00000394267	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000540147	ENST00000580825	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000540147	ENST00000254079	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000540147	ENST00000579000	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000540147	ENST00000394265	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000540147	ENST00000394267	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584450	ENST00000580825	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584450	ENST00000254079	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584450	ENST00000579000	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584450	ENST00000394265	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584450	ENST00000394267	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000269571	ENST00000580825	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000269571	ENST00000254079	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000269571	ENST00000579000	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000269571	ENST00000394265	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
In-frame	ENST00000269571	ENST00000394267	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000580825	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000254079	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000579000	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000394265	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000578199	ENST00000394267	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000580825	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000254079	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000579000	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000394265	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000540042	ENST00000394267	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000580825	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000254079	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000579000	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000394265	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+
intron-3CDS	ENST00000584888	ENST00000394267	ERBB2	chr17	37883799	+	PPP1R1B	chr17	37791859	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for ERBB2-PPP1R1B

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792068	+	0.41850367	0.58149636
ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792068	+	0.41850367	0.58149636
ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+	0.000232385	0.9997676
ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+	0.000232385	0.9997676
ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+	3.00E-05	0.9999701
ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+	3.00E-05	0.9999701
ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+	3.00E-05	0.9999701
ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785422	+	1.35E-05	0.9999865
ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790135	+	2.06E-07	0.99999976
ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790135	+	1.21E-07	0.9999999
ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790135	+	5.24E-11	1
ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792068	+	0.41850367	0.58149636
ERBB2	chr17	37876087	+	PPP1R1B	chr17	37792068	+	0.41850367	0.58149636
ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+	0.000232385	0.9997676
ERBB2	chr17	37883256	+	PPP1R1B	chr17	37791859	+	0.000232385	0.9997676
ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+	3.00E-05	0.9999701
ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+	3.00E-05	0.9999701
ERBB2	chr17	37883800	+	PPP1R1B	chr17	37791859	+	3.00E-05	0.9999701
ERBB2	chr17	37856564	+	PPP1R1B	chr17	37785422	+	1.35E-05	0.9999865
ERBB2	chr17	37856564	+	PPP1R1B	chr17	37790135	+	2.06E-07	0.99999976
ERBB2	chr17	37866734	+	PPP1R1B	chr17	37790135	+	1.21E-07	0.9999999
ERBB2	chr17	37872192	+	PPP1R1B	chr17	37790135	+	5.24E-11	1

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ERBB2-PPP1R1B

Go to
FGviewer for the breakpoints of chr17:37866734-chr17:37790136
.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ERBB2 P04626	.
FUNCTION: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. {ECO:0000305}.; FUNCTION: In the nucleus is involved in transcriptional regulation. Associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. Implicated in transcriptional activation of CDKN1A; the function involves STAT3 and SRC. Involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth. {ECO:0000269\|PubMed:10358079, ECO:0000269\|PubMed:15380516, ECO:0000269\|PubMed:21555369}.	FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000269571

720_987

1137.3333333333333

1256.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000541774

720_987

1122.3333333333333

1241.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000269571

720_987

1137.3333333333333

1256.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000541774

720_987

1122.3333333333333

1241.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000269571

720_987

1137.3333333333333

1256.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000541774

720_987

1122.3333333333333

1241.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000269571

676_689

1137.3333333333333

1256.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000541774

676_689

1122.3333333333333

1241.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000269571

676_689

1137.3333333333333

1256.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000541774

676_689

1122.3333333333333

1241.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000269571

676_689

1137.3333333333333

1256.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000541774

676_689

1122.3333333333333

1241.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000269571

726_734

1137.3333333333333

1256.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000541774

726_734

1122.3333333333333

1241.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000269571

726_734

1137.3333333333333

1256.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000541774

726_734

1122.3333333333333

1241.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000269571

726_734

1137.3333333333333

1256.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000541774

726_734

1122.3333333333333

1241.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000269571

23_652

1137.3333333333333

1256.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000541774

23_652

1122.3333333333333

1241.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000269571

23_652

1137.3333333333333

1256.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000541774

23_652

1122.3333333333333

1241.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000269571

23_652

1137.3333333333333

1256.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000541774

23_652

1122.3333333333333

1241.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000269571

653_675

1137.3333333333333

1256.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000541774

653_675

1122.3333333333333

1241.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000269571

653_675

1137.3333333333333

1256.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000541774

653_675

1122.3333333333333

1241.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000269571

653_675

1137.3333333333333

1256.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000541774

653_675

1122.3333333333333

1241.0

Transmembrane

Helical

Tgene

PPP1R1B

chr17:37856564

chr17:37790136

ENST00000254079

119_136

80.33333333333333

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37856564

chr17:37790136

ENST00000394265

119_136

44.333333333333336

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37856564

chr17:37790136

ENST00000394267

119_136

44.333333333333336

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37856564

chr17:37790136

ENST00000580825

119_136

80.33333333333333

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37866734

chr17:37790136

ENST00000254079

119_136

80.33333333333333

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37866734

chr17:37790136

ENST00000394265

119_136

44.333333333333336

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37866734

chr17:37790136

ENST00000394267

119_136

44.333333333333336

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37866734

chr17:37790136

ENST00000580825

119_136

80.33333333333333

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37872192

chr17:37790136

ENST00000254079

119_136

80.33333333333333

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37872192

chr17:37790136

ENST00000394265

119_136

44.333333333333336

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37872192

chr17:37790136

ENST00000394267

119_136

44.333333333333336

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37872192

chr17:37790136

ENST00000580825

119_136

80.33333333333333

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883799

chr17:37791859

ENST00000394265

119_136

112.33333333333333

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883799

chr17:37791859

ENST00000394267

119_136

112.33333333333333

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883800

chr17:37791859

ENST00000394265

119_136

112.33333333333333

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883800

chr17:37791859

ENST00000394267

119_136

112.33333333333333

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883800

chr17:37791860

ENST00000394265

119_136

112.33333333333333

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883800

chr17:37791860

ENST00000394267

119_136

112.33333333333333

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000269571

720_987

24.333333333333332

1256.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000541774

720_987

0.0

1241.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000269571

720_987

300.3333333333333

1256.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000541774

720_987

285.3333333333333

1241.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000269571

720_987

504.3333333333333

1256.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000541774

720_987

489.3333333333333

1241.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000269571

720_987

648.6666666666666

1256.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000541774

720_987

633.6666666666666

1241.0

Domain

Protein kinase

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000269571

676_689

24.333333333333332

1256.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000541774

676_689

0.0

1241.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000269571

676_689

300.3333333333333

1256.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000541774

676_689

285.3333333333333

1241.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000269571

676_689

504.3333333333333

1256.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000541774

676_689

489.3333333333333

1241.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000269571

676_689

648.6666666666666

1256.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000541774

676_689

633.6666666666666

1241.0

Motif

Note=Nuclear localization signal

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000269571

726_734

24.333333333333332

1256.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000541774

726_734

0.0

1241.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000269571

726_734

300.3333333333333

1256.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000541774

726_734

285.3333333333333

1241.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000269571

726_734

504.3333333333333

1256.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000541774

726_734

489.3333333333333

1241.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000269571

726_734

648.6666666666666

1256.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000541774

726_734

633.6666666666666

1241.0

Nucleotide binding

ATP

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000269571

23_652

24.333333333333332

1256.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000269571

676_1255

24.333333333333332

1256.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000541774

23_652

0.0

1241.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000541774

676_1255

0.0

1241.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000269571

23_652

300.3333333333333

1256.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000269571

676_1255

300.3333333333333

1256.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000541774

23_652

285.3333333333333

1241.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000541774

676_1255

285.3333333333333

1241.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000269571

23_652

504.3333333333333

1256.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000269571

676_1255

504.3333333333333

1256.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000541774

23_652

489.3333333333333

1241.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000541774

676_1255

489.3333333333333

1241.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000269571

23_652

648.6666666666666

1256.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000269571

676_1255

648.6666666666666

1256.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000541774

23_652

633.6666666666666

1241.0

Topological domain

Extracellular

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000541774

676_1255

633.6666666666666

1241.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000269571

676_1255

1137.3333333333333

1256.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37883799

chr17:37791859

ENST00000541774

676_1255

1122.3333333333333

1241.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000269571

676_1255

1137.3333333333333

1256.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37883800

chr17:37791859

ENST00000541774

676_1255

1122.3333333333333

1241.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000269571

676_1255

1137.3333333333333

1256.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37883800

chr17:37791860

ENST00000541774

676_1255

1122.3333333333333

1241.0

Topological domain

Cytoplasmic

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000269571

653_675

24.333333333333332

1256.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37856564

chr17:37790136

ENST00000541774

653_675

0.0

1241.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000269571

653_675

300.3333333333333

1256.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37866734

chr17:37790136

ENST00000541774

653_675

285.3333333333333

1241.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000269571

653_675

504.3333333333333

1256.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37872192

chr17:37790136

ENST00000541774

653_675

489.3333333333333

1241.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000269571

653_675

648.6666666666666

1256.0

Transmembrane

Helical

Hgene

ERBB2

chr17:37876087

chr17:37792069

ENST00000541774

653_675

633.6666666666666

1241.0

Transmembrane

Helical

Tgene

PPP1R1B

chr17:37876087

chr17:37792069

ENST00000254079

119_136

188.33333333333334

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37876087

chr17:37792069

ENST00000394265

119_136

152.33333333333334

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37876087

chr17:37792069

ENST00000394267

119_136

152.33333333333334

169.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37876087

chr17:37792069

ENST00000580825

119_136

188.33333333333334

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883799

chr17:37791859

ENST00000254079

119_136

148.33333333333334

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883799

chr17:37791859

ENST00000580825

119_136

148.33333333333334

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883800

chr17:37791859

ENST00000254079

119_136

148.33333333333334

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883800

chr17:37791859

ENST00000580825

119_136

148.33333333333334

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883800

chr17:37791860

ENST00000254079

119_136

148.33333333333334

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

PPP1R1B

chr17:37883800

chr17:37791860

ENST00000580825

119_136

148.33333333333334

205.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Top

Fusion Gene Sequence for ERBB2-PPP1R1B

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

Top

Fusion Gene PPI Analysis for ERBB2-PPP1R1B

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	ERBB2	chr17:37856564	chr17:37790136	ENST00000269571	+	1	27	1195_1197	24.333333333333332	1256.0	PIK3C2B
Hgene	ERBB2	chr17:37856564	chr17:37790136	ENST00000541774	+	1	27	1195_1197	0.0	1241.0	PIK3C2B
Hgene	ERBB2	chr17:37866734	chr17:37790136	ENST00000269571	+	7	27	1195_1197	300.3333333333333	1256.0	PIK3C2B
Hgene	ERBB2	chr17:37866734	chr17:37790136	ENST00000541774	+	7	27	1195_1197	285.3333333333333	1241.0	PIK3C2B
Hgene	ERBB2	chr17:37872192	chr17:37790136	ENST00000269571	+	12	27	1195_1197	504.3333333333333	1256.0	PIK3C2B
Hgene	ERBB2	chr17:37872192	chr17:37790136	ENST00000541774	+	12	27	1195_1197	489.3333333333333	1241.0	PIK3C2B
Hgene	ERBB2	chr17:37876087	chr17:37792069	ENST00000269571	+	16	27	1195_1197	648.6666666666666	1256.0	PIK3C2B
Hgene	ERBB2	chr17:37876087	chr17:37792069	ENST00000541774	+	16	27	1195_1197	633.6666666666666	1241.0	PIK3C2B
Hgene	ERBB2	chr17:37883799	chr17:37791859	ENST00000269571	+	26	27	1195_1197	1137.3333333333333	1256.0	PIK3C2B
Hgene	ERBB2	chr17:37883799	chr17:37791859	ENST00000541774	+	26	27	1195_1197	1122.3333333333333	1241.0	PIK3C2B
Hgene	ERBB2	chr17:37883800	chr17:37791859	ENST00000269571	+	26	27	1195_1197	1137.3333333333333	1256.0	PIK3C2B
Hgene	ERBB2	chr17:37883800	chr17:37791859	ENST00000541774	+	26	27	1195_1197	1122.3333333333333	1241.0	PIK3C2B
Hgene	ERBB2	chr17:37883800	chr17:37791860	ENST00000269571	+	26	27	1195_1197	1137.3333333333333	1256.0	PIK3C2B
Hgene	ERBB2	chr17:37883800	chr17:37791860	ENST00000541774	+	26	27	1195_1197	1122.3333333333333	1241.0	PIK3C2B

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for ERBB2-PPP1R1B

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner	Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Hgene	ERBB2	P04626	DB06366	Pertuzumab	Inhibitor	Biotech	Approved
Hgene	ERBB2	P04626	DB06366	Pertuzumab	Inhibitor	Biotech	Approved
Hgene	ERBB2	P04626	DB06366	Pertuzumab	Inhibitor	Biotech	Approved
Hgene	ERBB2	P04626	DB06366	Pertuzumab	Inhibitor	Biotech	Approved
Hgene	ERBB2	P04626	DB06366	Pertuzumab	Inhibitor	Biotech	Approved
Hgene	ERBB2	P04626	DB08916	Afatinib	Inhibitor	Small molecule	Approved
Hgene	ERBB2	P04626	DB08916	Afatinib	Inhibitor	Small molecule	Approved
Hgene	ERBB2	P04626	DB08916	Afatinib	Inhibitor	Small molecule	Approved
Hgene	ERBB2	P04626	DB08916	Afatinib	Inhibitor	Small molecule	Approved
Hgene	ERBB2	P04626	DB08916	Afatinib	Inhibitor	Small molecule	Approved
Hgene	ERBB2	P04626	DB00072	Trastuzumab	Antibody	Biotech	Approved\|Investigational
Hgene	ERBB2	P04626	DB00072	Trastuzumab	Antibody	Biotech	Approved\|Investigational
Hgene	ERBB2	P04626	DB00072	Trastuzumab	Antibody	Biotech	Approved\|Investigational
Hgene	ERBB2	P04626	DB00072	Trastuzumab	Antibody	Biotech	Approved\|Investigational
Hgene	ERBB2	P04626	DB00072	Trastuzumab	Antibody	Biotech	Approved\|Investigational
Hgene	ERBB2	P04626	DB01259	Lapatinib	Antagonist	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB01259	Lapatinib	Antagonist	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB01259	Lapatinib	Antagonist	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB01259	Lapatinib	Antagonist	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB01259	Lapatinib	Antagonist	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB05773	Trastuzumab emtansine	Antibody	Biotech	Approved\|Investigational
Hgene	ERBB2	P04626	DB05773	Trastuzumab emtansine	Antibody	Biotech	Approved\|Investigational
Hgene	ERBB2	P04626	DB05773	Trastuzumab emtansine	Antibody	Biotech	Approved\|Investigational
Hgene	ERBB2	P04626	DB05773	Trastuzumab emtansine	Antibody	Biotech	Approved\|Investigational
Hgene	ERBB2	P04626	DB05773	Trastuzumab emtansine	Antibody	Biotech	Approved\|Investigational
Hgene	ERBB2	P04626	DB11652	Tucatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB11652	Tucatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB11652	Tucatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB11652	Tucatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB11652	Tucatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB12010	Fostamatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB12010	Fostamatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB12010	Fostamatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB12010	Fostamatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB12010	Fostamatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB12267	Brigatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB12267	Brigatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB12267	Brigatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB12267	Brigatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB12267	Brigatinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB15035	Zanubrutinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB15035	Zanubrutinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB15035	Zanubrutinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB15035	Zanubrutinib	Inhibitor	Small molecule	Approved\|Investigational
Hgene	ERBB2	P04626	DB15035	Zanubrutinib	Inhibitor	Small molecule	Approved\|Investigational

Top

Related Diseases for ERBB2-PPP1R1B

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	ERBB2	C0006142	Malignant neoplasm of breast	40	CGI;CTD_human
Hgene	ERBB2	C0678222	Breast Carcinoma	40	CGI;CTD_human
Hgene	ERBB2	C1257931	Mammary Neoplasms, Human	40	CTD_human
Hgene	ERBB2	C1458155	Mammary Neoplasms	40	CTD_human
Hgene	ERBB2	C4704874	Mammary Carcinoma, Human	40	CTD_human
Hgene	ERBB2	C1140680	Malignant neoplasm of ovary	4	CGI;CTD_human;UNIPROT
Hgene	ERBB2	C0024623	Malignant neoplasm of stomach	3	CGI;CTD_human
Hgene	ERBB2	C0033578	Prostatic Neoplasms	3	CTD_human
Hgene	ERBB2	C0038356	Stomach Neoplasms	3	CGI;CTD_human
Hgene	ERBB2	C0235874	Disease Exacerbation	3	CTD_human
Hgene	ERBB2	C0376358	Malignant neoplasm of prostate	3	CTD_human
Hgene	ERBB2	C1708349	Hereditary Diffuse Gastric Cancer	3	CTD_human
Hgene	ERBB2	C0001418	Adenocarcinoma	2	CTD_human
Hgene	ERBB2	C0024668	Mammary Neoplasms, Experimental	2	CTD_human
Hgene	ERBB2	C0205641	Adenocarcinoma, Basal Cell	2	CTD_human
Hgene	ERBB2	C0205642	Adenocarcinoma, Oxyphilic	2	CTD_human
Hgene	ERBB2	C0205643	Carcinoma, Cribriform	2	CTD_human
Hgene	ERBB2	C0205644	Carcinoma, Granular Cell	2	CTD_human
Hgene	ERBB2	C0205645	Adenocarcinoma, Tubular	2	CTD_human
Hgene	ERBB2	C0699791	Stomach Carcinoma	2	CGI;UNIPROT
Hgene	ERBB2	C0919267	ovarian neoplasm	2	CGI;CTD_human
Hgene	ERBB2	C0007102	Malignant tumor of colon	1	CTD_human
Hgene	ERBB2	C0007134	Renal Cell Carcinoma	1	CTD_human
Hgene	ERBB2	C0009375	Colonic Neoplasms	1	CTD_human
Hgene	ERBB2	C0013930	Embolism, Tumor	1	CTD_human
Hgene	ERBB2	C0014859	Esophageal Neoplasms	1	CTD_human
Hgene	ERBB2	C0016978	gallbladder neoplasm	1	CTD_human
Hgene	ERBB2	C0017185	Gastrointestinal Neoplasms	1	CTD_human
Hgene	ERBB2	C0021367	Mammary Ductal Carcinoma	1	CTD_human
Hgene	ERBB2	C0024121	Lung Neoplasms	1	CTD_human
Hgene	ERBB2	C0024232	Lymphatic Metastasis	1	CTD_human
Hgene	ERBB2	C0024667	Animal Mammary Neoplasms	1	CTD_human
Hgene	ERBB2	C0025149	Medulloblastoma	1	CTD_human
Hgene	ERBB2	C0027627	Neoplasm Metastasis	1	CTD_human
Hgene	ERBB2	C0027643	Neoplasm Recurrence, Local	1	CTD_human
Hgene	ERBB2	C0027659	Neoplasms, Experimental	1	CTD_human
Hgene	ERBB2	C0030354	Papilloma	1	CTD_human
Hgene	ERBB2	C0153452	Malignant neoplasm of gallbladder	1	CTD_human
Hgene	ERBB2	C0205833	Medullomyoblastoma	1	CTD_human
Hgene	ERBB2	C0205874	Papilloma, Squamous Cell	1	CTD_human
Hgene	ERBB2	C0205875	Papillomatosis	1	CTD_human
Hgene	ERBB2	C0206698	Cholangiocarcinoma	1	CTD_human
Hgene	ERBB2	C0242379	Malignant neoplasm of lung	1	CTD_human
Hgene	ERBB2	C0278510	Childhood Medulloblastoma	1	CTD_human
Hgene	ERBB2	C0278876	Adult Medulloblastoma	1	CTD_human
Hgene	ERBB2	C0279702	Conventional (Clear Cell) Renal Cell Carcinoma	1	CTD_human
Hgene	ERBB2	C0345905	Intrahepatic Cholangiocarcinoma	1	CTD_human
Hgene	ERBB2	C0546837	Malignant neoplasm of esophagus	1	CTD_human
Hgene	ERBB2	C0596263	Carcinogenesis	1	CTD_human
Hgene	ERBB2	C0684249	Carcinoma of lung	1	UNIPROT
Hgene	ERBB2	C0685938	Malignant neoplasm of gastrointestinal tract	1	CTD_human
Hgene	ERBB2	C0751291	Desmoplastic Medulloblastoma	1	CTD_human
Hgene	ERBB2	C1134719	Invasive Ductal Breast Carcinoma	1	CTD_human
Hgene	ERBB2	C1257925	Mammary Carcinoma, Animal	1	CTD_human
Hgene	ERBB2	C1266042	Chromophobe Renal Cell Carcinoma	1	CTD_human
Hgene	ERBB2	C1266043	Sarcomatoid Renal Cell Carcinoma	1	CTD_human
Hgene	ERBB2	C1266044	Collecting Duct Carcinoma of the Kidney	1	CTD_human
Hgene	ERBB2	C1275668	Melanotic medulloblastoma	1	CTD_human
Hgene	ERBB2	C1306837	Papillary Renal Cell Carcinoma	1	CTD_human
Hgene	ERBB2	C1368275	Pigmented Basal Cell Carcinoma	1	CTD_human
Hgene	ERBB2	C2750850	GLIOMA SUSCEPTIBILITY 1	1	UNIPROT
Hgene	ERBB2	C2931822	Nasopharyngeal carcinoma	1	CTD_human
Hgene	ERBB2	C3805278	Extrahepatic Cholangiocarcinoma	1	CTD_human
Hgene	ERBB2	C4721610	Carcinoma, Ovarian Epithelial	1	CTD_human
Hgene	ERBB2	C4721806	Carcinoma, Basal Cell	1	CTD_human
Tgene	PPP1R1B	C0036341	Schizophrenia	5	PSYGENET
Tgene	PPP1R1B	C0005586	Bipolar Disorder	4	PSYGENET
Tgene	PPP1R1B	C0001973	Alcoholic Intoxication, Chronic	1	PSYGENET
Tgene	PPP1R1B	C0007370	Catalepsy	1	CTD_human
Tgene	PPP1R1B	C0011570	Mental Depression	1	PSYGENET
Tgene	PPP1R1B	C0011581	Depressive disorder	1	PSYGENET
Tgene	PPP1R1B	C0013384	Dyskinetic syndrome	1	CTD_human
Tgene	PPP1R1B	C0152115	Lingual-Facial-Buccal Dyskinesia	1	CTD_human
Tgene	PPP1R1B	C0221169	Hemiballismus	1	CTD_human
Tgene	PPP1R1B	C0232766	Asterixis	1	CTD_human
Tgene	PPP1R1B	C0233612	Waxy flexibility	1	CTD_human
Tgene	PPP1R1B	C0427086	Involuntary Movements	1	CTD_human
Tgene	PPP1R1B	C0454606	Oral Dyskinesia	1	CTD_human
Tgene	PPP1R1B	C0752196	Ballismus	1	CTD_human