FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:FAF1-FNBP1L (FusionGDB2 ID:28154)

Fusion Gene Summary for FAF1-FNBP1L

check button Fusion gene summary
Fusion gene informationFusion gene name: FAF1-FNBP1L
Fusion gene ID: 28154
HgeneTgene
Gene symbol

FAF1

FNBP1L

Gene ID

11124

54874

Gene nameFas associated factor 1formin binding protein 1 like
SynonymsCGI-03|HFAF1s|UBXD12|UBXN3A|hFAF1C1orf39|TOCA1
Cytomap

1p32.3

1p22.1

Type of geneprotein-codingprotein-coding
DescriptionFAS-associated factor 1Fas (TNFRSF6) associated factor 1TNFRSF6-associated factor 1UBX domain protein 3AUBX domain-containing protein 12UBX domain-containing protein 3Aformin-binding protein 1-liketoca-1transducer of Cdc42-dependent actin assembly 1transducer of Cdc42-dependent actin assembly protein 1
Modification date2020031320200313
UniProtAcc

Q9UNN5

Q5T0N5

Ensembl transtripts involved in fusion geneENST00000396153, ENST00000371778, 
ENST00000545823, ENST00000472808, 
ENST00000370256, ENST00000260506, 
ENST00000271234, ENST00000604705, 
ENST00000370253, 
Fusion gene scores* DoF score23 X 21 X 9=434710 X 7 X 4=280
# samples 3110
** MAII scorelog2(31/4347*10)=-3.80967997500385
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/280*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FAF1 [Title/Abstract] AND FNBP1L [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFAF1(51425438)-FNBP1L(93965024), # samples:1
Anticipated loss of major functional domain due to fusion event.FAF1-FNBP1L seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
FAF1-FNBP1L seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFAF1

GO:0010942

positive regulation of cell death

15596450

TgeneFNBP1L

GO:0006900

vesicle budding from membrane

20730103

TgeneFNBP1L

GO:0010324

membrane invagination

20730103

TgeneFNBP1L

GO:0016050

vesicle organization

20730103

TgeneFNBP1L

GO:0030050

vesicle transport along actin filament

20730103

TgeneFNBP1L

GO:0051491

positive regulation of filopodium assembly

20730103

TgeneFNBP1L

GO:0072583

clathrin-dependent endocytosis

20730103

TgeneFNBP1L

GO:0097320

plasma membrane tubulation

20730103


check buttonFusion gene breakpoints across FAF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across FNBP1L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-Z6-A8JEFAF1chr1

51425438

-FNBP1Lchr1

93965024

+


Top

Fusion Gene ORF analysis for FAF1-FNBP1L

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000396153ENST00000370256FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
In-frameENST00000396153ENST00000260506FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
In-frameENST00000396153ENST00000271234FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
In-frameENST00000396153ENST00000604705FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
In-frameENST00000396153ENST00000370253FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
Frame-shiftENST00000371778ENST00000370256FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
Frame-shiftENST00000371778ENST00000260506FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
Frame-shiftENST00000371778ENST00000271234FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
Frame-shiftENST00000371778ENST00000604705FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
Frame-shiftENST00000371778ENST00000370253FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
intron-3CDSENST00000545823ENST00000370256FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
intron-3CDSENST00000545823ENST00000260506FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
intron-3CDSENST00000545823ENST00000271234FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
intron-3CDSENST00000545823ENST00000604705FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
intron-3CDSENST00000545823ENST00000370253FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
intron-3CDSENST00000472808ENST00000370256FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
intron-3CDSENST00000472808ENST00000260506FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
intron-3CDSENST00000472808ENST00000271234FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
intron-3CDSENST00000472808ENST00000604705FAF1chr1

51425438

-FNBP1Lchr1

93965024

+
intron-3CDSENST00000472808ENST00000370253FAF1chr1

51425438

-FNBP1Lchr1

93965024

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000396153FAF1chr151425438-ENST00000370256FNBP1Lchr193965024+45194971402275711
ENST00000396153FAF1chr151425438-ENST00000260506FNBP1Lchr193965024+56634971402128662
ENST00000396153FAF1chr151425438-ENST00000271234FNBP1Lchr193965024+45344971402290716
ENST00000396153FAF1chr151425438-ENST00000604705FNBP1Lchr193965024+23034971402302721
ENST00000396153FAF1chr151425438-ENST00000370253FNBP1Lchr193965024+43624971402116658

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000396153ENST00000370256FAF1chr151425438-FNBP1Lchr193965024+9.02E-050.99990976
ENST00000396153ENST00000260506FAF1chr151425438-FNBP1Lchr193965024+5.92E-050.99994075
ENST00000396153ENST00000271234FAF1chr151425438-FNBP1Lchr193965024+0.000115330.9998846
ENST00000396153ENST00000604705FAF1chr151425438-FNBP1Lchr193965024+0.0015170630.998483
ENST00000396153ENST00000370253FAF1chr151425438-FNBP1Lchr193965024+9.11E-050.9999089

Top

Fusion Genomic Features for FAF1-FNBP1L


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FAF1chr151425438-FNBP1Lchr193965024+4.16E-111
FAF1chr151425438-FNBP1Lchr193965024+4.16E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for FAF1-FNBP1L


check button Go to

FGviewer for the breakpoints of chr1:51425438-chr1:93965024

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FAF1

Q9UNN5

FNBP1L

Q5T0N5

FUNCTION: Ubiquitin-binding protein (PubMed:19722279). Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation (PubMed:26842564). Potentiates but cannot initiate FAS-induced apoptosis (By similarity). {ECO:0000250|UniProtKB:P54731, ECO:0000269|PubMed:19722279, ECO:0000269|PubMed:26842564}.FUNCTION: Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens. {ECO:0000269|PubMed:15260990, ECO:0000269|PubMed:16326391, ECO:0000269|PubMed:19342671}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000260506014392_4848.0552.0Coiled coilOntology_term=ECO:0000250
TgeneFNBP1Lchr1:51425438chr1:93965024ENST0000026050601466_2588.0552.0Coiled coilOntology_term=ECO:0000250
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370253015392_4848.0548.0Coiled coilOntology_term=ECO:0000250
TgeneFNBP1Lchr1:51425438chr1:93965024ENST0000037025301566_2588.0548.0Coiled coilOntology_term=ECO:0000250
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370256016392_4848.0601.0Coiled coilOntology_term=ECO:0000250
TgeneFNBP1Lchr1:51425438chr1:93965024ENST0000037025601666_2588.0601.0Coiled coilOntology_term=ECO:0000250
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000260506014397_4748.0552.0DomainREM-1
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000260506014538_5998.0552.0DomainSH3
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370253015397_4748.0548.0DomainREM-1
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370253015538_5998.0548.0DomainSH3
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370256016397_4748.0601.0DomainREM-1
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370256016538_5998.0601.0DomainSH3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAF1chr1:51425438chr1:93965024ENST00000371778-2201_5715.0651.0DomainUBA
HgeneFAF1chr1:51425438chr1:93965024ENST00000371778-220569_64615.0651.0DomainUBX
HgeneFAF1chr1:51425438chr1:93965024ENST00000396153-1191_5715.0651.0DomainUBA
HgeneFAF1chr1:51425438chr1:93965024ENST00000396153-119569_64615.0651.0DomainUBX
TgeneFNBP1Lchr1:51425438chr1:93965024ENST000002605060141_2638.0552.0DomainF-BAR
TgeneFNBP1Lchr1:51425438chr1:93965024ENST000003702530151_2638.0548.0DomainF-BAR
TgeneFNBP1Lchr1:51425438chr1:93965024ENST000003702560161_2638.0601.0DomainF-BAR


Top

Fusion Gene Sequence for FAF1-FNBP1L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000396153_ENST00000370256_TCGA-Z6-A8JE_FAF1_chr1_51425438_-_FNBP1L_chr1_93965024_length(transcript)=4519nt_BP=497nt
AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC
CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC
ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC
ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC
GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG
CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGATCAGTTCGACAGCTTAGACAAGCATACACAATGGGGAATTG
ACTTCTTGGAAAGATATGCCAAATTTGTTAAAGAGAGGATAGAAATTGAACAGAACTATGCGAAACAATTGAGAAATCTGGTTAAGAAGT
ACTGCCCCAAACGTTCATCCAAAGATGAAGAGCCACGGTTTACCTCGTGTGTAGCCTTTTTTAATATCCTTAATGAGTTAAATGACTATG
CAGGACAGCGAGAAGTTGTAGCAGAAGAAATGGCGCACAGAGTGTATGGTGAATTAATGAGATATGCTCATGATCTGAAAACTGAAAGAA
AAATGCATCTGCAAGAAGGACGAAAAGCTCAACAATATCTTGACATGTGCTGGAAACAGATGGATAATAGTAAAAAGAAGTTTGAAAGAG
AATGTAGAGAGGCAGAAAAGGCACAACAGAGTTATGAAAGATTGGATAATGATACTAATGCAACCAAGGCAGATGTTGAAAAGGCCAAAC
AGCAGTTGAATCTGCGTACGCATATGGCCGATGAAAATAAAAATGAATATGCTGCACAATTACAAAACTTTAATGGAGAACAACATAAAC
ATTTTTATGTAGTGATTCCTCAGATTTACAAGCAACTACAAGAAATGGACGAACGAAGGACTATTAAACTCAGTGAGTGTTACAGAGGAT
TTGCTGACTCAGAACGCAAAGTTATTCCCATCATTTCAAAATGTTTGGAAGGAATGATTCTTGCAGCAAAATCAGTTGATGAAAGAAGAG
ACTCTCAAATGGTGGTAGACTCCTTCAAATCTGGTTTTGAACCTCCAGGAGACTTTCCATTTGAAGATTACAGTCAACATATATATAGAA
CCATTTCTGATGGGACTATCAGTGCATCCAAACAGGAGAGTGGGAAGATGGATGCCAAAACCACAGTAGGAAAGGCCAAGGGCAAATTGT
GGCTCTTTGGAAAGAAGCCAAAGCCACAGTCCCCACCCTTAACCCCTACTAGTTTATTCACATCCAGTACTCCTAATGGGTCCCAGTTTC
TCACATTCTCCATTGAGCCCGTGCATTATTGTATGAATGAAATAAAAACAGGGAAGCCCAGAATTCCTTCTTTCAGAAGCCTCAAAAGAG
GGGGCCCAGCACTAGAAGATTTCAGTCATCTGCCACCAGAACAGAGACGTAAAAAACTACAGCAGCGCATTGATGAACTTAACAGAGAAC
TACAGAAAGAATCAGACCAAAAAGATGCACTCAACAAAATGAAAGATGTATATGAGAAGAATCCACAAATGGGGGATCCAGGGAGTTTGC
AGCCTAAATTAGCAGAGACCATGAATAACATTGACCGCCTACGAATGGAAATCCATAAGAATGAGGCTTGGCTCTCTGAAGTCGAAGGCA
AAACAGGTGGGAGAGGAGACAGAAGACATAGCAGTGACATAAATCATCTTGTAACACAGGGACGAGAAAGTCCTGAGGGAAGTTACACTG
ATGATGCAAACCAGGAAGTCCGTGGGCCACCCCAGCAGCATGGTCACCACAATGAGTTTGATGATGAATTTGAGGATGATGATCCCTTGC
CTGCTATTGGACACTGCAAAGCTATCTACCCTTTTGATGGACATAATGAAGGTACTCTAGCAATGAAAGAAGGTGAAGTTCTCTACATTA
TAGAGGAGGACAAAGGTGACGGATGGACAAGAGCTCGGAGACAGAACGGTGAAGAAGGCTACGTTCCCACGTCATACATAGATGTAACTC
TAGAGAAAAACAGTAAAGGTTCCTGAAGAGGGTTTCTGAGGAAATGGGCAAGATGTTGAAGGAGGTTACATGCAGCTGCTTTTGGGGGAG
GGTATTAGAGTTGTCAGGCTCAAAGAGAGTGAGAGAAGCAAGTTGCATGAGTGCATGCAGACATGATTTTTTTTTTACTAACTTCATTAG
CATTTCCATACATTGTTTTTAAAAATCATAATACCAACCCTTAAGTTCCTAGTTCACAGTTATTCCCACAAAAGAAAAAGCCAACAATAG
TGTACCATTTTTCTATTTATTTTATTGCTGTCTAATCAATAAAGAATGCAGAGCTGTCAAAAAATGTGTCTTACATTAGCTGTCCCAACA
GGATTGTCTTCCCTCCCAGCTCTGTTTTAATTGGCTTTTAGACCCACTATCTGTCAGATCCTTGCCATCTGTCAGTGTCTGCCTGCGCCA
CCTCCGTGCTTGCTTAACATCCTGTTGCATGTCTAGCGTGATTGAGCTAGATTTTTCAGGCATGTCTTTAGATTCCCTTGTTCTTGTCAA
AGCCTTGTTTTGTTTTACATTTGTAGTGCAAATCACTTTGTCAAACATCTCCAGCACTAATGTTTCCATCTTAGTATTTGTGCACACTGC
TATAACTTCCCCACTGCAAACATTCCAGTTTTGGCATTACGAAGAAGTAGCTGTGAACCTGAAGTATTTATGATAAGAAAAAGAAAACAT
CTCTGCTGTAGCCTACAGCCCAGTTGAAAGAACTCTTTGAAACGTGATACATCTTCAGCACCTCAGTCTGGGAAGAATCTAGTCAGCACT
GAAATCCTGGCATAATAAACACAGAAGATATTCACCACCTCAAGACAAAGGACTATTGTCAAAAGTCAGCTGCTTCCATTCAAATGCTGC
CTTAAACTTGAGTGCCTAAATCTGTTGATTGCCAACACTACCACTACAGTATCCCACAAAGGGCTTTATGTGTCAGCTCAGTGCGACCTG
CTTTAACTCTGCAGCACCGCTGCAGCTGCCGATGTAGCCTCGGTAGGTGGCTATTAGAGCTCTACCATATACAGTGGTGCATCTTCAAAT
TTATGCATCAAACTAAAGACATGTCCAAGTCCATTTTAATTTCCTCAGTGGTTTTATGAGAAGTTTTATGGGCCTCCCCCAATTGTCTTT
TTATTTTGGGTTATGACGATCATGTTTGATAATTACAATGATAGTCTCTTTCCACGTGATGCTTTTGTTTGAACCTGATAAAATTTAGTG
AAACTTTGTAATGATCTATGTGCACTTTTACTTGTAAAATGGAATTTCTGTATGTTTATACTTGTAAATATGATTGTTGTTAGTGCTCCT
GTTGCTCATGGTGTCCTGCCTCGCATTTGTGATTCTGTTAATGACATGTATCTTAACTAATTTCTTAGTGGTGTTGTAATAGGGAGATGG
GGCAGGTGGGGGGTTATTTGTACCACTGAATCTTCATTAATTTGGTTCTTTACTGTTTTGAGGGGAGAAAGAACGTGAAATGGTTTGTGT
ATTATTGAATTTTAAGCAATATTTTAGAAGCTGTGTGACTGCTTTAATAACTTTTTCCCAGTGTTATTTGAATCATACTACCCGTTATAC
TAAAGCTGAATGACAATTGTGTGAAAGTTACTGCCTTCATAAGATCAAGTCACCACTGTTACACAGCTGACATATAGTGTATTACCTTTG
CAGCTAGTAAACTATAAAGTTTAGATATTGAATCTCGTTACAGGGTTATTTATATAATGTGACATTATTCAGTACTGACAGACTACATGA
AGTAGTTTTAAAATCTAGTGCTATTTTTATTTTAAAGGTTAGCAATGAGGAGGAAATGTGATCTGGCTGTGTTTGTCTTCTGTACAAAGC
CTGAAGTGCTTATGGTTTTTTGGCTAACAGCCACAGAGGGCAAAGTTTAAGACTTTCTTGTAAGGACTAACTGTTCTTTTCAAGCTACTG
TTTGTTTTTCTAAAAGCAGGATTTGCTTCCGTAGGAGGCAAGTTCCTTGATGTGGAATAGTGCAACCTGTATATGGGTTATTATAATAGG
AAAGACATTTGTACTTGCACAGTTTAAATCATTCTTAAATTTTGAACATGTGAATTGTCCCAAAAAATCTTTAATTTTTTGGTAATTTTT
ACTCTTTTTGTGCACATGTTGATTTCTTAATGGTAAATCCTTCATTTAAAGATAGTGTTCTCTGTTGAGAATATTTACATGGAATAAAAC

>In-frame_ENST00000396153_ENST00000370256_TCGA-Z6-A8JE_FAF1_chr1_51425438_-_FNBP1L_chr1_93965024_length(amino acids)=711AA_start in transcript=140_stop in transcript=2275
MPSSWPATVRPDPHPDQSSCPGCCDAGSAGCRRAAGAPEGYRVHERLALPALPRPLARRPARRLARQPLGARRRRRRWRRRSQEVPSASQ
VRASLPEPRNSAAAMASNMDREMILADFQDQFDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEEPRFTSC
VAFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCWKQMDNSKKKFERECREAEKAQQSYERLDN
DTNATKADVEKAKQQLNLRTHMADENKNEYAAQLQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFADSERKVIPIISKCLE
GMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDYSQHIYRTISDGTISASKQESGKMDAKTTVGKAKGKLWLFGKKPKPQSPPLTPT
SLFTSSTPNGSQFLTFSIEPVHYCMNEIKTGKPRIPSFRSLKRGGPALEDFSHLPPEQRRKKLQQRIDELNRELQKESDQKDALNKMKDV
YEKNPQMGDPGSLQPKLAETMNNIDRLRMEIHKNEAWLSEVEGKTGGRGDRRHSSDINHLVTQGRESPEGSYTDDANQEVRGPPQQHGHH

--------------------------------------------------------------
>In-frame_ENST00000396153_ENST00000260506_TCGA-Z6-A8JE_FAF1_chr1_51425438_-_FNBP1L_chr1_93965024_length(transcript)=5663nt_BP=497nt
AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC
CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC
ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC
ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC
GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG
CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGATCAGTTCGACAGCTTAGACAAGCATACACAATGGGGAATTG
ACTTCTTGGAAAGATATGCCAAATTTGTTAAAGAGAGGATAGAAATTGAACAGAACTATGCGAAACAATTGAGAAATCTGGTTAAGAAGT
ACTGCCCCAAACGTTCATCCAAAGATGAAGAGCCACGGTTTACCTCGTGTGTAGCCTTTTTTAATATCCTTAATGAGTTAAATGACTATG
CAGGACAGCGAGAAGTTGTAGCAGAAGAAATGGCGCACAGAGTGTATGGTGAATTAATGAGATATGCTCATGATCTGAAAACTGAAAGAA
AAATGCATCTGCAAGAAGGACGAAAAGCTCAACAATATCTTGACATGTGCTGGAAACAGATGGATAATAGTAAAAAGAAGTTTGAAAGAG
AATGTAGAGAGGCAGAAAAGGCACAACAGAGTTATGAAAGATTGGATAATGATACTAATGCAACCAAGGCAGATGTTGAAAAGGCCAAAC
AGCAGTTGAATCTGCGTACGCATATGGCCGATGAAAATAAAAATGAATATGCTGCACAATTACAAAACTTTAATGGAGAACAACATAAAC
ATTTTTATGTAGTGATTCCTCAGATTTACAAGCAACTACAAGAAATGGACGAACGAAGGACTATTAAACTCAGTGAGTGTTACAGAGGAT
TTGCTGACTCAGAACGCAAAGTTATTCCCATCATTTCAAAATGTTTGGAAGGAATGATTCTTGCAGCAAAATCAGTTGATGAAAGAAGAG
ACTCTCAAATGGTGGTAGACTCCTTCAAATCTGGTTTTGAACCTCCAGGAGACTTTCCATTTGAAGATTACAGTCAACATATATATAGAA
CCATTTCTGATGGGACTATCAGTGCATCCAAACAGGAGAGTGGGAAGATGGATGCCAAAACCACAGTAGGAAAGGCCAAGGGCAAATTGT
GGCTCTTTGGAAAGAAGCCAAAGGGCCCAGCACTAGAAGATTTCAGTCATCTGCCACCAGAACAGAGACGTAAAAAACTACAGCAGCGCA
TTGATGAACTTAACAGAGAACTACAGAAAGAATCAGACCAAAAAGATGCACTCAACAAAATGAAAGATGTATATGAGAAGAATCCACAAA
TGGGGGATCCAGGGAGTTTGCAGCCTAAATTAGCAGAGACCATGAATAACATTGACCGCCTACGAATGGAAATCCATAAGAATGAGGCTT
GGCTCTCTGAAGTCGAAGGCAAAACAGGTGGGAGAGGAGACAGAAGACATAGCAGTGACATAAATCATCTTGTAACACAGGGACGAGAAA
GTCCTGAGGGAAGTTACACTGATGATGCAAACCAGGAAGTCCGTGGGCCACCCCAGCAGCATGGTCACCACAATGAGTTTGATGATGAAT
TTGAGGATGATGATCCCTTGCCTGCTATTGGACACTGCAAAGCTATCTACCCTTTTGATGGACATAATGAAGGTACTCTAGCAATGAAAG
AAGGTGAAGTTCTCTACATTATAGAGGAGGACAAAGGTGACGGATGGACAAGAGCTCGGAGACAGAACGGTGAAGAAGGCTACGTTCCCA
CGTCATACATAGATGTAACTCTAGAGAAAAACAGTAAAGGTGCAGTAACTTATATCTAAACTAACCAGGCACCTTTGTGCCATGTGTGAC
ATAGGAAGAGTAACATAAAATGAAAACACATTCAACAGGTTGAAAAAAATAAGGAAACTTAAAGGGCATCCAAGATTAATTGTTCACTAT
GTGAGCTGAGTGTAGGCTTGATCTTGTGAATATTACCACAAGAAACATTTTGTGGCACTTTACTGTTTGAGTAACGTTGGTGTGAAGCTT
AATTGATGCCTTTTGCTTTATGTCCCGCTTAAGTCTGTGTGAAGGATTTGTGTTTTTCTGCCTTACAAATAGAATTTGATTTATTGGGCA
GGAATTCATGGATAGTAATGCTCTCTGCCCCCTTTACTTCAGAAAACACAGTGACTTTAGTGAATTTGAATAGTGAAACTGCTCTGAAAT
GCTATGGAAAGCCGACTCCCCAAAGAGTGGTTTCTTCTAGAAGTTTGAATTTGTAGCTACAGTTTCCAAGAAGAAAAATAGTAGTTGGAT
AATTTAGTAAAATAATAACATCATTTTCATTTTCTTACCTATTCTTAACTTTGGTTTCCTAAAGGAAGAAAATGAGCAGGTAGCACATAA
TCTATTTAAGTAGATTTAAAGAGAGTTTCAAAATAAATCTCCTGGTCTAGCTCTTAGGTGAATAAAATAGATTTTGTTTGAGACCTCAAA
ATATTTTGAGGTTAGCTGGTAATTTTCAATAATTTACAAGCTTCCTTCCAAACTAATCTCATACTTTTGTATGTTTCATCTTGAAAATAT
CTTTTGGGAAATACCACTTTAGTGATTATTTAGCATTTAGCAGTTACACATAGGAAAATACACAGTTACATAGAAAAATACACATTTGAA
GATAGAGGAAACCTTGAATGGAGGGGAAGTGTTGACAAATTTTAATTTTTAAAGGAGAAACTTTTTGACTATCTGGGTTAGAGGAAGATA
TGTGTACCGCCTTTAGGGCATTTTGTTATTTCCGCTGAATCATTAGTTATTAGGATAGATAAATTTTTCCAATTAGTTTCAGCAAGCGTT
GTTGGAAACACTGTGCAGTCAAGGATTGTGCAGTGCTGGTTGTGTGACCACACCCTGAGTCAGTGGTGTGGGGAAGTAAAGTGTGAAGAA
GCAGTAAGATTGGTTTTTAATTTTGCCCATGTTTTAAATTTTCCTGGTGTTTTCGGTAGCTGACTATAAAATGATAGAGACATTTGGGAC
AGGCACTTTAAACTGAACACCCCTTTTGGTTTTACCAAAGGTCTTCAGTAATTGTTCTTTTCTTTTTCCTCCTGGACTGCAGGTTCCTGA
AGAGGGTTTCTGAGGAAATGGGCAAGATGTTGAAGGAGGTTACATGCAGCTGCTTTTGGGGGAGGGTATTAGAGTTGTCAGGCTCAAAGA
GAGTGAGAGAAGCAAGTTGCATGAGTGCATGCAGACATGATTTTTTTTTTACTAACTTCATTAGCATTTCCATACATTGTTTTTAAAAAT
CATAATACCAACCCTTAAGTTCCTAGTTCACAGTTATTCCCACAAAAGAAAAAGCCAACAATAGTGTACCATTTTTCTATTTATTTTATT
GCTGTCTAATCAATAAAGAATGCAGAGCTGTCAAAAAATGTGTCTTACATTAGCTGTCCCAACAGGATTGTCTTCCCTCCCAGCTCTGTT
TTAATTGGCTTTTAGACCCACTATCTGTCAGATCCTTGCCATCTGTCAGTGTCTGCCTGCGCCACCTCCGTGCTTGCTTAACATCCTGTT
GCATGTCTAGCGTGATTGAGCTAGATTTTTCAGGCATGTCTTTAGATTCCCTTGTTCTTGTCAAAGCCTTGTTTTGTTTTACATTTGTAG
TGCAAATCACTTTGTCAAACATCTCCAGCACTAATGTTTCCATCTTAGTATTTGTGCACACTGCTATAACTTCCCCACTGCAAACATTCC
AGTTTTGGCATTACGAAGAAGTAGCTGTGAACCTGAAGTATTTATGATAAGAAAAAGAAAACATCTCTGCTGTAGCCTACAGCCCAGTTG
AAAGAACTCTTTGAAACGTGATACATCTTCAGCACCTCAGTCTGGGAAGAATCTAGTCAGCACTGAAATCCTGGCATAATAAACACAGAA
GATATTCACCACCTCAAGACAAAGGACTATTGTCAAAAGTCAGCTGCTTCCATTCAAATGCTGCCTTAAACTTGAGTGCCTAAATCTGTT
GATTGCCAACACTACCACTACAGTATCCCACAAAGGGCTTTATGTGTCAGCTCAGTGCGACCTGCTTTAACTCTGCAGCACCGCTGCAGC
TGCCGATGTAGCCTCGGTAGGTGGCTATTAGAGCTCTACCATATACAGTGGTGCATCTTCAAATTTATGCATCAAACTAAAGACATGTCC
AAGTCCATTTTAATTTCCTCAGTGGTTTTATGAGAAGTTTTATGGGCCTCCCCCAATTGTCTTTTTATTTTGGGTTATGACGATCATGTT
TGATAATTACAATGATAGTCTCTTTCCACGTGATGCTTTTGTTTGAACCTGATAAAATTTAGTGAAACTTTGTAATGATCTATGTGCACT
TTTACTTGTAAAATGGAATTTCTGTATGTTTATACTTGTAAATATGATTGTTGTTAGTGCTCCTGTTGCTCATGGTGTCCTGCCTCGCAT
TTGTGATTCTGTTAATGACATGTATCTTAACTAATTTCTTAGTGGTGTTGTAATAGGGAGATGGGGCAGGTGGGGGGTTATTTGTACCAC
TGAATCTTCATTAATTTGGTTCTTTACTGTTTTGAGGGGAGAAAGAACGTGAAATGGTTTGTGTATTATTGAATTTTAAGCAATATTTTA
GAAGCTGTGTGACTGCTTTAATAACTTTTTCCCAGTGTTATTTGAATCATACTACCCGTTATACTAAAGCTGAATGACAATTGTGTGAAA
GTTACTGCCTTCATAAGATCAAGTCACCACTGTTACACAGCTGACATATAGTGTATTACCTTTGCAGCTAGTAAACTATAAAGTTTAGAT
ATTGAATCTCGTTACAGGGTTATTTATATAATGTGACATTATTCAGTACTGACAGACTACATGAAGTAGTTTTAAAATCTAGTGCTATTT
TTATTTTAAAGGTTAGCAATGAGGAGGAAATGTGATCTGGCTGTGTTTGTCTTCTGTACAAAGCCTGAAGTGCTTATGGTTTTTTGGCTA
ACAGCCACAGAGGGCAAAGTTTAAGACTTTCTTGTAAGGACTAACTGTTCTTTTCAAGCTACTGTTTGTTTTTCTAAAAGCAGGATTTGC
TTCCGTAGGAGGCAAGTTCCTTGATGTGGAATAGTGCAACCTGTATATGGGTTATTATAATAGGAAAGACATTTGTACTTGCACAGTTTA
AATCATTCTTAAATTTTGAACATGTGAATTGTCCCAAAAAATCTTTAATTTTTTGGTAATTTTTACTCTTTTTGTGCACATGTTGATTTC

>In-frame_ENST00000396153_ENST00000260506_TCGA-Z6-A8JE_FAF1_chr1_51425438_-_FNBP1L_chr1_93965024_length(amino acids)=662AA_start in transcript=140_stop in transcript=2128
MPSSWPATVRPDPHPDQSSCPGCCDAGSAGCRRAAGAPEGYRVHERLALPALPRPLARRPARRLARQPLGARRRRRRWRRRSQEVPSASQ
VRASLPEPRNSAAAMASNMDREMILADFQDQFDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEEPRFTSC
VAFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCWKQMDNSKKKFERECREAEKAQQSYERLDN
DTNATKADVEKAKQQLNLRTHMADENKNEYAAQLQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFADSERKVIPIISKCLE
GMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDYSQHIYRTISDGTISASKQESGKMDAKTTVGKAKGKLWLFGKKPKGPALEDFSH
LPPEQRRKKLQQRIDELNRELQKESDQKDALNKMKDVYEKNPQMGDPGSLQPKLAETMNNIDRLRMEIHKNEAWLSEVEGKTGGRGDRRH
SSDINHLVTQGRESPEGSYTDDANQEVRGPPQQHGHHNEFDDEFEDDDPLPAIGHCKAIYPFDGHNEGTLAMKEGEVLYIIEEDKGDGWT

--------------------------------------------------------------
>In-frame_ENST00000396153_ENST00000271234_TCGA-Z6-A8JE_FAF1_chr1_51425438_-_FNBP1L_chr1_93965024_length(transcript)=4534nt_BP=497nt
AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC
CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC
ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC
ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC
GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG
CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGATCAGTTCGACAGCTTAGACAAGCATACACAATGGGGAATTG
ACTTCTTGGAAAGATATGCCAAATTTGTTAAAGAGAGGATAGAAATTGAACAGAACTATGCGAAACAATTGAGAAATCTGGTTAAGAAGT
ACTGCCCCAAACGTTCATCCAAAGATGAAGAGCCACGGTTTACCTCGTGTGTAGCCTTTTTTAATATCCTTAATGAGTTAAATGACTATG
CAGGACAGCGAGAAGTTGTAGCAGAAGAAATGGCGCACAGAGTGTATGGTGAATTAATGAGATATGCTCATGATCTGAAAACTGAAAGAA
AAATGCATCTGCAAGAAGGACGAAAAGCTCAACAATATCTTGACATGTGCTGGAAACAGATGGATAATAGTAAAAAGAAGTTTGAAAGAG
AATGTAGAGAGGCAGAAAAGGCACAACAGAGTTATGAAAGATTGGATAATGATACTAATGCAACCAAGGCAGATGTTGAAAAGGCCAAAC
AGCAGTTGAATCTGCGTACGCATATGGCCGATGAAAATAAAAATGAATATGCTGCACAATTACAAAACTTTAATGGAGAACAACATAAAC
ATTTTTATGTAGTGATTCCTCAGATTTACAAGCAACTACAAGAAATGGACGAACGAAGGACTATTAAACTCAGTGAGTGTTACAGAGGAT
TTGCTGACTCAGAACGCAAAGTTATTCCCATCATTTCAAAATGTTTGGAAGGAATGATTCTTGCAGCAAAATCAGTTGATGAAAGAAGAG
ACTCTCAAATGGTGGTAGACTCCTTCAAATCTGGTTTTGAACCTCCAGGAGACTTTCCATTTGAAGATTACAGTCAACATATATATAGAA
CCATTTCTGATGGGACTATCAGTGCATCCAAACAGGAGAGTGGGAAGATGGATGCCAAAACCACAGTAGGAAAGGCCAAGGGCAAATTGT
GGCTCTTTGGAAAGAAGCCAAAGCCACAGTCCCCACCCTTAACCCCTACTAGTTTATTCACATCCAGTACTCCTAATGGGTCCCAGTTTC
TCACATTCTCCATTGAGCCCGTGCATTATTGTATGAATGAAATAAAAACAGGGAAGCCCAGAATTCCTTCTTTCAGAAGCCTCAAAAGAG
GGTGGTCGGTGAAGATGGGCCCAGCACTAGAAGATTTCAGTCATCTGCCACCAGAACAGAGACGTAAAAAACTACAGCAGCGCATTGATG
AACTTAACAGAGAACTACAGAAAGAATCAGACCAAAAAGATGCACTCAACAAAATGAAAGATGTATATGAGAAGAATCCACAAATGGGGG
ATCCAGGGAGTTTGCAGCCTAAATTAGCAGAGACCATGAATAACATTGACCGCCTACGAATGGAAATCCATAAGAATGAGGCTTGGCTCT
CTGAAGTCGAAGGCAAAACAGGTGGGAGAGGAGACAGAAGACATAGCAGTGACATAAATCATCTTGTAACACAGGGACGAGAAAGTCCTG
AGGGAAGTTACACTGATGATGCAAACCAGGAAGTCCGTGGGCCACCCCAGCAGCATGGTCACCACAATGAGTTTGATGATGAATTTGAGG
ATGATGATCCCTTGCCTGCTATTGGACACTGCAAAGCTATCTACCCTTTTGATGGACATAATGAAGGTACTCTAGCAATGAAAGAAGGTG
AAGTTCTCTACATTATAGAGGAGGACAAAGGTGACGGATGGACAAGAGCTCGGAGACAGAACGGTGAAGAAGGCTACGTTCCCACGTCAT
ACATAGATGTAACTCTAGAGAAAAACAGTAAAGGTTCCTGAAGAGGGTTTCTGAGGAAATGGGCAAGATGTTGAAGGAGGTTACATGCAG
CTGCTTTTGGGGGAGGGTATTAGAGTTGTCAGGCTCAAAGAGAGTGAGAGAAGCAAGTTGCATGAGTGCATGCAGACATGATTTTTTTTT
TACTAACTTCATTAGCATTTCCATACATTGTTTTTAAAAATCATAATACCAACCCTTAAGTTCCTAGTTCACAGTTATTCCCACAAAAGA
AAAAGCCAACAATAGTGTACCATTTTTCTATTTATTTTATTGCTGTCTAATCAATAAAGAATGCAGAGCTGTCAAAAAATGTGTCTTACA
TTAGCTGTCCCAACAGGATTGTCTTCCCTCCCAGCTCTGTTTTAATTGGCTTTTAGACCCACTATCTGTCAGATCCTTGCCATCTGTCAG
TGTCTGCCTGCGCCACCTCCGTGCTTGCTTAACATCCTGTTGCATGTCTAGCGTGATTGAGCTAGATTTTTCAGGCATGTCTTTAGATTC
CCTTGTTCTTGTCAAAGCCTTGTTTTGTTTTACATTTGTAGTGCAAATCACTTTGTCAAACATCTCCAGCACTAATGTTTCCATCTTAGT
ATTTGTGCACACTGCTATAACTTCCCCACTGCAAACATTCCAGTTTTGGCATTACGAAGAAGTAGCTGTGAACCTGAAGTATTTATGATA
AGAAAAAGAAAACATCTCTGCTGTAGCCTACAGCCCAGTTGAAAGAACTCTTTGAAACGTGATACATCTTCAGCACCTCAGTCTGGGAAG
AATCTAGTCAGCACTGAAATCCTGGCATAATAAACACAGAAGATATTCACCACCTCAAGACAAAGGACTATTGTCAAAAGTCAGCTGCTT
CCATTCAAATGCTGCCTTAAACTTGAGTGCCTAAATCTGTTGATTGCCAACACTACCACTACAGTATCCCACAAAGGGCTTTATGTGTCA
GCTCAGTGCGACCTGCTTTAACTCTGCAGCACCGCTGCAGCTGCCGATGTAGCCTCGGTAGGTGGCTATTAGAGCTCTACCATATACAGT
GGTGCATCTTCAAATTTATGCATCAAACTAAAGACATGTCCAAGTCCATTTTAATTTCCTCAGTGGTTTTATGAGAAGTTTTATGGGCCT
CCCCCAATTGTCTTTTTATTTTGGGTTATGACGATCATGTTTGATAATTACAATGATAGTCTCTTTCCACGTGATGCTTTTGTTTGAACC
TGATAAAATTTAGTGAAACTTTGTAATGATCTATGTGCACTTTTACTTGTAAAATGGAATTTCTGTATGTTTATACTTGTAAATATGATT
GTTGTTAGTGCTCCTGTTGCTCATGGTGTCCTGCCTCGCATTTGTGATTCTGTTAATGACATGTATCTTAACTAATTTCTTAGTGGTGTT
GTAATAGGGAGATGGGGCAGGTGGGGGGTTATTTGTACCACTGAATCTTCATTAATTTGGTTCTTTACTGTTTTGAGGGGAGAAAGAACG
TGAAATGGTTTGTGTATTATTGAATTTTAAGCAATATTTTAGAAGCTGTGTGACTGCTTTAATAACTTTTTCCCAGTGTTATTTGAATCA
TACTACCCGTTATACTAAAGCTGAATGACAATTGTGTGAAAGTTACTGCCTTCATAAGATCAAGTCACCACTGTTACACAGCTGACATAT
AGTGTATTACCTTTGCAGCTAGTAAACTATAAAGTTTAGATATTGAATCTCGTTACAGGGTTATTTATATAATGTGACATTATTCAGTAC
TGACAGACTACATGAAGTAGTTTTAAAATCTAGTGCTATTTTTATTTTAAAGGTTAGCAATGAGGAGGAAATGTGATCTGGCTGTGTTTG
TCTTCTGTACAAAGCCTGAAGTGCTTATGGTTTTTTGGCTAACAGCCACAGAGGGCAAAGTTTAAGACTTTCTTGTAAGGACTAACTGTT
CTTTTCAAGCTACTGTTTGTTTTTCTAAAAGCAGGATTTGCTTCCGTAGGAGGCAAGTTCCTTGATGTGGAATAGTGCAACCTGTATATG
GGTTATTATAATAGGAAAGACATTTGTACTTGCACAGTTTAAATCATTCTTAAATTTTGAACATGTGAATTGTCCCAAAAAATCTTTAAT
TTTTTGGTAATTTTTACTCTTTTTGTGCACATGTTGATTTCTTAATGGTAAATCCTTCATTTAAAGATAGTGTTCTCTGTTGAGAATATT

>In-frame_ENST00000396153_ENST00000271234_TCGA-Z6-A8JE_FAF1_chr1_51425438_-_FNBP1L_chr1_93965024_length(amino acids)=716AA_start in transcript=140_stop in transcript=2290
MPSSWPATVRPDPHPDQSSCPGCCDAGSAGCRRAAGAPEGYRVHERLALPALPRPLARRPARRLARQPLGARRRRRRWRRRSQEVPSASQ
VRASLPEPRNSAAAMASNMDREMILADFQDQFDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEEPRFTSC
VAFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCWKQMDNSKKKFERECREAEKAQQSYERLDN
DTNATKADVEKAKQQLNLRTHMADENKNEYAAQLQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFADSERKVIPIISKCLE
GMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDYSQHIYRTISDGTISASKQESGKMDAKTTVGKAKGKLWLFGKKPKPQSPPLTPT
SLFTSSTPNGSQFLTFSIEPVHYCMNEIKTGKPRIPSFRSLKRGWSVKMGPALEDFSHLPPEQRRKKLQQRIDELNRELQKESDQKDALN
KMKDVYEKNPQMGDPGSLQPKLAETMNNIDRLRMEIHKNEAWLSEVEGKTGGRGDRRHSSDINHLVTQGRESPEGSYTDDANQEVRGPPQ

--------------------------------------------------------------
>In-frame_ENST00000396153_ENST00000604705_TCGA-Z6-A8JE_FAF1_chr1_51425438_-_FNBP1L_chr1_93965024_length(transcript)=2303nt_BP=497nt
AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC
CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC
ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC
ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC
GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG
CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGATCAGTTCGACAGCTTAGACAAGCATACACAATGGGGAATTG
ACTTCTTGGAAAGATATGCCAAATTTGTTAAAGAGAGGATAGAAATTGAACAGAACTATGCGAAACAATTGAGAAATCTGGTTAAGAAGT
ACTGCCCCAAACGTTCATCCAAAGATGAAGAGCCACGGTTTACCTCGTGTGTAGCCTTTTTTAATATCCTTAATGAGTTAAATGACTATG
CAGGACAGCGAGAAGTTGTAGCAGAAGAAATGGCGCACAGAGTGTATGGTGAATTAATGAGATATGCTCATGATCTGAAAACTGAAAGAA
AAATGCATCTGCAAGAAGGACGAAAAGCTCAACAATATCTTGACATGTGCTGGAAACAGATGGATAATAGTAAAAAGAAGTTTGAAAGAG
AATGTAGAGAGGCAGAAAAGGCACAACAGAGTTATGAAAGATTGGATAATGATACTAATGCAACCAAGGCAGATGTTGAAAAGGCCAAAC
AGCAGTTGAATCTGCGTACGCATATGGCCGATGAAAATAAAAATGAATATGCTGCACAATTACAAAACTTTAATGGAGAACAACATAAAC
ATTTTTATGTAGTGATTCCTCAGATTTACAAGCAACTACAAGAAATGGACGAACGAAGGACTATTAAACTCAGTGAGTGTTACAGAGGAT
TTGCTGACTCAGAACGCAAAGTTATTCCCATCATTTCAAAATGTTTGGAAGGAATGATTCTTGCAGCAAAATCAGTTGATGAAAGAAGAG
ACTCTCAAATGGTGGTAGACTCCTTCAAATCTGGTTTTGAACCTCCAGGAGACTTTCCATTTGAAGATTACAGTCAACATATATATAGAA
CCATTTCTGATGGGACTATCAGTGCATCCAAACAGGAGAGTGGGAAGATGGATGCCAAAACCACAGTAGGAAAGGCCAAGGGCAAATTGT
GGCTCTTTGGAAAGAAGCCAAAGCCACAGTCCCCACCCTTAACCCCTACTAGTTTATTCACATCCAGTACTCCTAATGGGTCCCAGTTTC
TCACATTCTCCATTGAGCCCGTGCATTATTGTATGAATGAAATAAAAACAGGGAAGCCCAGAATTCCTTCTTTCAGAAGCCTCAAAAGAG
GGTGGTCGGTGAAGATGGGCCCAGCACTAGAAGATTTCAGTCATCTGCCACCAGAACAGAGACGTAAAAAACTACAGCAGCGCATTGATG
AACTTAACAGAGAACTACAGAAAGAATCAGACCAAAAAGATGCACTCAACAAAATGAAAGATGTATATGAGAAGAATCCACAAATGGGGG
ATCCAGGGAGTTTGCAGCCTAAATTAGCAGAGACCATGAATAACATTGACCGCCTACGAATGGAAATCCATAAGAATGAGGCTTGGCTCT
CTGAAGTCGAAGGCAAAACAGGTGGGAGAGGAGACAGAAGACATAGCAGTGACATAAATCATCTTGTAACACAGGGACGAGAAAGTCCTG
AGGGAAGTTACACTGATGATGCAAACCAGGAAGTCCGTGGGCCACCCCAGCAGCATGGTCACCACAATGAGTTTGATGATGAATTTGAGG
ATGATGATCCCTTGCCTGCTATTGGACACTGCAAAGCTATCTACCCTTTTGATGGACATAATGAAGGTACTCTAGCAATGAAAGAAGGTG
AAGTTCTCTACATTATAGAGGAGGACAAAGGTGACGGATGGACAAGAGCTCGGAGACAGAACGGTGAAGAAGGCTACGTTCCCACGTCAT

>In-frame_ENST00000396153_ENST00000604705_TCGA-Z6-A8JE_FAF1_chr1_51425438_-_FNBP1L_chr1_93965024_length(amino acids)=721AA_start in transcript=140_stop in transcript=2302
MPSSWPATVRPDPHPDQSSCPGCCDAGSAGCRRAAGAPEGYRVHERLALPALPRPLARRPARRLARQPLGARRRRRRWRRRSQEVPSASQ
VRASLPEPRNSAAAMASNMDREMILADFQDQFDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEEPRFTSC
VAFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCWKQMDNSKKKFERECREAEKAQQSYERLDN
DTNATKADVEKAKQQLNLRTHMADENKNEYAAQLQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFADSERKVIPIISKCLE
GMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDYSQHIYRTISDGTISASKQESGKMDAKTTVGKAKGKLWLFGKKPKPQSPPLTPT
SLFTSSTPNGSQFLTFSIEPVHYCMNEIKTGKPRIPSFRSLKRGWSVKMGPALEDFSHLPPEQRRKKLQQRIDELNRELQKESDQKDALN
KMKDVYEKNPQMGDPGSLQPKLAETMNNIDRLRMEIHKNEAWLSEVEGKTGGRGDRRHSSDINHLVTQGRESPEGSYTDDANQEVRGPPQ
QHGHHNEFDDEFEDDDPLPAIGHCKAIYPFDGHNEGTLAMKEGEVLYIIEEDKGDGWTRARRQNGEEGYVPTSYIDVTLEKNSKGAVTYI

--------------------------------------------------------------
>In-frame_ENST00000396153_ENST00000370253_TCGA-Z6-A8JE_FAF1_chr1_51425438_-_FNBP1L_chr1_93965024_length(transcript)=4362nt_BP=497nt
AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC
CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC
ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC
ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC
GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG
CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGATCAGTTCGACAGCTTAGACAAGCATACACAATGGGGAATTG
ACTTCTTGGAAAGATATGCCAAATTTGTTAAAGAGAGGATAGAAATTGAACAGAACTATGCGAAACAATTGAGAAATCTGGTTAAGAAGT
ACTGCCCCAAACGTTCATCCAAAGATGAAGAGCCACGGTTTACCTCGTGTGTAGCCTTTTTTAATATCCTTAATGAGTTAAATGACTATG
CAGGACAGCGAGAAGTTGTAGCAGAAGAAATGGCGCACAGAGTGTATGGTGAATTAATGAGATATGCTCATGATCTGAAAACTGAAAGAA
AAATGCATCTGCAAGAAGGACGAAAAGCTCAACAATATCTTGACATGTGCTGGAAACAGATGGATAATAGTAAAAAGAAGTTTGAAAGAG
AATGTAGAGAGGCAGAAAAGGCACAACAGAGTTATGAAAGATTGGATAATGATACTAATGCAACCAAGGCAGATGTTGAAAAGGCCAAAC
AGCAGTTGAATCTGCGTACGCATATGGCCGATGAAAATAAAAATGAATATGCTGCACAATTACAAAACTTTAATGGAGAACAACATAAAC
ATTTTTATGTAGTGATTCCTCAGATTTACAAGCAACTACAAGAAATGGACGAACGAAGGACTATTAAACTCAGTGAGTGTTACAGAGGAT
TTGCTGACTCAGAACGCAAAGTTATTCCCATCATTTCAAAATGTTTGGAAGGAATGATTCTTGCAGCAAAATCAGTTGATGAAAGAAGAG
ACTCTCAAATGGTGGTAGACTCCTTCAAATCTGGTTTTGAACCTCCAGGAGACTTTCCATTTGAAGATTACAGTCAACATATATATAGAA
CCATTTCTGATGGGACTATCAGTGCATCCAAACAGGAGAGTGGGAAGATGGATGCCAAAACCACAGTAGGAAAGGCCAAGGGCAAATTGT
GGCTCTTTGGAAAGAAGCCAAAGGGCCCAGCACTAGAAGATTTCAGTCATCTGCCACCAGAACAGAGACGTAAAAAACTACAGCAGCGCA
TTGATGAACTTAACAGAGAACTACAGAAAGAATCAGACCAAAAAGATGCACTCAACAAAATGAAAGATGTATATGAGAAGAATCCACAAA
TGGGGGATCCAGGGAGTTTGCAGCCTAAATTAGCAGAGACCATGAATAACATTGACCGCCTACGAATGGAAATCCATAAGAATGAGGCTT
GGCTCTCTGAAGTCGAAGGCAAAACAGGTGGGAGAGGAGACAGAAGACATAGCAGTGACATAAATCATCTTGTAACACAGGGACGAGAAA
GTCCTGAGGGAAGTTACACTGATGATGCAAACCAGGAAGTCCGTGGGCCACCCCAGCAGCATGGTCACCACAATGAGTTTGATGATGAAT
TTGAGGATGATGATCCCTTGCCTGCTATTGGACACTGCAAAGCTATCTACCCTTTTGATGGACATAATGAAGGTACTCTAGCAATGAAAG
AAGGTGAAGTTCTCTACATTATAGAGGAGGACAAAGGTGACGGATGGACAAGAGCTCGGAGACAGAACGGTGAAGAAGGCTACGTTCCCA
CGTCATACATAGATGTAACTCTAGAGAAAAACAGTAAAGGTTCCTGAAGAGGGTTTCTGAGGAAATGGGCAAGATGTTGAAGGAGGTTAC
ATGCAGCTGCTTTTGGGGGAGGGTATTAGAGTTGTCAGGCTCAAAGAGAGTGAGAGAAGCAAGTTGCATGAGTGCATGCAGACATGATTT
TTTTTTTACTAACTTCATTAGCATTTCCATACATTGTTTTTAAAAATCATAATACCAACCCTTAAGTTCCTAGTTCACAGTTATTCCCAC
AAAAGAAAAAGCCAACAATAGTGTACCATTTTTCTATTTATTTTATTGCTGTCTAATCAATAAAGAATGCAGAGCTGTCAAAAAATGTGT
CTTACATTAGCTGTCCCAACAGGATTGTCTTCCCTCCCAGCTCTGTTTTAATTGGCTTTTAGACCCACTATCTGTCAGATCCTTGCCATC
TGTCAGTGTCTGCCTGCGCCACCTCCGTGCTTGCTTAACATCCTGTTGCATGTCTAGCGTGATTGAGCTAGATTTTTCAGGCATGTCTTT
AGATTCCCTTGTTCTTGTCAAAGCCTTGTTTTGTTTTACATTTGTAGTGCAAATCACTTTGTCAAACATCTCCAGCACTAATGTTTCCAT
CTTAGTATTTGTGCACACTGCTATAACTTCCCCACTGCAAACATTCCAGTTTTGGCATTACGAAGAAGTAGCTGTGAACCTGAAGTATTT
ATGATAAGAAAAAGAAAACATCTCTGCTGTAGCCTACAGCCCAGTTGAAAGAACTCTTTGAAACGTGATACATCTTCAGCACCTCAGTCT
GGGAAGAATCTAGTCAGCACTGAAATCCTGGCATAATAAACACAGAAGATATTCACCACCTCAAGACAAAGGACTATTGTCAAAAGTCAG
CTGCTTCCATTCAAATGCTGCCTTAAACTTGAGTGCCTAAATCTGTTGATTGCCAACACTACCACTACAGTATCCCACAAAGGGCTTTAT
GTGTCAGCTCAGTGCGACCTGCTTTAACTCTGCAGCACCGCTGCAGCTGCCGATGTAGCCTCGGTAGGTGGCTATTAGAGCTCTACCATA
TACAGTGGTGCATCTTCAAATTTATGCATCAAACTAAAGACATGTCCAAGTCCATTTTAATTTCCTCAGTGGTTTTATGAGAAGTTTTAT
GGGCCTCCCCCAATTGTCTTTTTATTTTGGGTTATGACGATCATGTTTGATAATTACAATGATAGTCTCTTTCCACGTGATGCTTTTGTT
TGAACCTGATAAAATTTAGTGAAACTTTGTAATGATCTATGTGCACTTTTACTTGTAAAATGGAATTTCTGTATGTTTATACTTGTAAAT
ATGATTGTTGTTAGTGCTCCTGTTGCTCATGGTGTCCTGCCTCGCATTTGTGATTCTGTTAATGACATGTATCTTAACTAATTTCTTAGT
GGTGTTGTAATAGGGAGATGGGGCAGGTGGGGGGTTATTTGTACCACTGAATCTTCATTAATTTGGTTCTTTACTGTTTTGAGGGGAGAA
AGAACGTGAAATGGTTTGTGTATTATTGAATTTTAAGCAATATTTTAGAAGCTGTGTGACTGCTTTAATAACTTTTTCCCAGTGTTATTT
GAATCATACTACCCGTTATACTAAAGCTGAATGACAATTGTGTGAAAGTTACTGCCTTCATAAGATCAAGTCACCACTGTTACACAGCTG
ACATATAGTGTATTACCTTTGCAGCTAGTAAACTATAAAGTTTAGATATTGAATCTCGTTACAGGGTTATTTATATAATGTGACATTATT
CAGTACTGACAGACTACATGAAGTAGTTTTAAAATCTAGTGCTATTTTTATTTTAAAGGTTAGCAATGAGGAGGAAATGTGATCTGGCTG
TGTTTGTCTTCTGTACAAAGCCTGAAGTGCTTATGGTTTTTTGGCTAACAGCCACAGAGGGCAAAGTTTAAGACTTTCTTGTAAGGACTA
ACTGTTCTTTTCAAGCTACTGTTTGTTTTTCTAAAAGCAGGATTTGCTTCCGTAGGAGGCAAGTTCCTTGATGTGGAATAGTGCAACCTG
TATATGGGTTATTATAATAGGAAAGACATTTGTACTTGCACAGTTTAAATCATTCTTAAATTTTGAACATGTGAATTGTCCCAAAAAATC
TTTAATTTTTTGGTAATTTTTACTCTTTTTGTGCACATGTTGATTTCTTAATGGTAAATCCTTCATTTAAAGATAGTGTTCTCTGTTGAG

>In-frame_ENST00000396153_ENST00000370253_TCGA-Z6-A8JE_FAF1_chr1_51425438_-_FNBP1L_chr1_93965024_length(amino acids)=658AA_start in transcript=140_stop in transcript=2116
MPSSWPATVRPDPHPDQSSCPGCCDAGSAGCRRAAGAPEGYRVHERLALPALPRPLARRPARRLARQPLGARRRRRRWRRRSQEVPSASQ
VRASLPEPRNSAAAMASNMDREMILADFQDQFDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEEPRFTSC
VAFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCWKQMDNSKKKFERECREAEKAQQSYERLDN
DTNATKADVEKAKQQLNLRTHMADENKNEYAAQLQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFADSERKVIPIISKCLE
GMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDYSQHIYRTISDGTISASKQESGKMDAKTTVGKAKGKLWLFGKKPKGPALEDFSH
LPPEQRRKKLQQRIDELNRELQKESDQKDALNKMKDVYEKNPQMGDPGSLQPKLAETMNNIDRLRMEIHKNEAWLSEVEGKTGGRGDRRH
SSDINHLVTQGRESPEGSYTDDANQEVRGPPQQHGHHNEFDDEFEDDDPLPAIGHCKAIYPFDGHNEGTLAMKEGEVLYIIEEDKGDGWT

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for FAF1-FNBP1L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000260506014245_5358.0552.0CDC42
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370253015245_5358.0548.0CDC42
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370256016245_5358.0601.0CDC42
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000260506014541_6058.0552.0DAAM1%2C DIAPH1 and DIAPH2
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370253015541_6058.0548.0DAAM1%2C DIAPH1 and DIAPH2
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370256016541_6058.0601.0DAAM1%2C DIAPH1 and DIAPH2
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000260506014522_6058.0552.0DNM1
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370253015522_6058.0548.0DNM1
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370256016522_6058.0601.0DNM1
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000260506014541_5978.0552.0DNM2 and WASL
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370253015541_5978.0548.0DNM2 and WASL
TgeneFNBP1Lchr1:51425438chr1:93965024ENST00000370256016541_5978.0601.0DNM2 and WASL


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for FAF1-FNBP1L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for FAF1-FNBP1L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource