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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FAF1-LRRC7 (FusionGDB2 ID:28161)

Fusion Gene Summary for FAF1-LRRC7

check button Fusion gene summary
Fusion gene informationFusion gene name: FAF1-LRRC7
Fusion gene ID: 28161
HgeneTgene
Gene symbol

FAF1

LRRC7

Gene ID

11124

57554

Gene nameFas associated factor 1leucine rich repeat containing 7
SynonymsCGI-03|HFAF1s|UBXD12|UBXN3A|hFAF1DENSIN
Cytomap

1p32.3

1p31.1

Type of geneprotein-codingprotein-coding
DescriptionFAS-associated factor 1Fas (TNFRSF6) associated factor 1TNFRSF6-associated factor 1UBX domain protein 3AUBX domain-containing protein 12UBX domain-containing protein 3Aleucine-rich repeat-containing protein 7densin-180
Modification date2020031320200313
UniProtAcc

Q9UNN5

Q8NAA5

Ensembl transtripts involved in fusion geneENST00000396153, ENST00000371778, 
ENST00000545823, ENST00000472808, 
ENST00000310961, ENST00000370958, 
ENST00000035383, ENST00000415775, 
ENST00000565615, 
Fusion gene scores* DoF score23 X 21 X 9=43475 X 5 X 2=50
# samples 315
** MAII scorelog2(31/4347*10)=-3.80967997500385
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/50*10)=0
Context

PubMed: FAF1 [Title/Abstract] AND LRRC7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFAF1(51323601)-LRRC7(70257726), # samples:3
Anticipated loss of major functional domain due to fusion event.FAF1-LRRC7 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
FAF1-LRRC7 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFAF1

GO:0010942

positive regulation of cell death

15596450


check buttonFusion gene breakpoints across FAF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across LRRC7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A209-01AFAF1chr1

51323601

-LRRC7chr1

70257726

+
ChimerDB4BRCATCGA-BH-A209-01AFAF1chr1

51323601

-LRRC7chr1

70257726

+
ChimerDB4BRCATCGA-BH-A209-01AFAF1chr1

51323601

-LRRC7chr1

70257726

+


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Fusion Gene ORF analysis for FAF1-LRRC7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000396153ENST00000310961FAF1chr1

51323601

-LRRC7chr1

70257726

+
In-frameENST00000396153ENST00000370958FAF1chr1

51323601

-LRRC7chr1

70257726

+
In-frameENST00000396153ENST00000035383FAF1chr1

51323601

-LRRC7chr1

70257726

+
5CDS-5UTRENST00000396153ENST00000415775FAF1chr1

51323601

-LRRC7chr1

70257726

+
5CDS-intronENST00000396153ENST00000565615FAF1chr1

51323601

-LRRC7chr1

70257726

+
Frame-shiftENST00000371778ENST00000310961FAF1chr1

51323601

-LRRC7chr1

70257726

+
Frame-shiftENST00000371778ENST00000370958FAF1chr1

51323601

-LRRC7chr1

70257726

+
Frame-shiftENST00000371778ENST00000035383FAF1chr1

51323601

-LRRC7chr1

70257726

+
5CDS-5UTRENST00000371778ENST00000415775FAF1chr1

51323601

-LRRC7chr1

70257726

+
5CDS-intronENST00000371778ENST00000565615FAF1chr1

51323601

-LRRC7chr1

70257726

+
intron-3CDSENST00000545823ENST00000310961FAF1chr1

51323601

-LRRC7chr1

70257726

+
intron-3CDSENST00000545823ENST00000370958FAF1chr1

51323601

-LRRC7chr1

70257726

+
intron-3CDSENST00000545823ENST00000035383FAF1chr1

51323601

-LRRC7chr1

70257726

+
intron-5UTRENST00000545823ENST00000415775FAF1chr1

51323601

-LRRC7chr1

70257726

+
intron-intronENST00000545823ENST00000565615FAF1chr1

51323601

-LRRC7chr1

70257726

+
intron-3CDSENST00000472808ENST00000310961FAF1chr1

51323601

-LRRC7chr1

70257726

+
intron-3CDSENST00000472808ENST00000370958FAF1chr1

51323601

-LRRC7chr1

70257726

+
intron-3CDSENST00000472808ENST00000035383FAF1chr1

51323601

-LRRC7chr1

70257726

+
intron-5UTRENST00000472808ENST00000415775FAF1chr1

51323601

-LRRC7chr1

70257726

+
intron-intronENST00000472808ENST00000565615FAF1chr1

51323601

-LRRC7chr1

70257726

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000396153FAF1chr151323601-ENST00000310961LRRC7chr170257726+645156614048491569
ENST00000396153FAF1chr151323601-ENST00000370958LRRC7chr170257726+2448566140916258
ENST00000396153FAF1chr151323601-ENST00000035383LRRC7chr170257726+534756614049901616

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000396153ENST00000310961FAF1chr151323601-LRRC7chr170257726+0.0003620370.99963796
ENST00000396153ENST00000370958FAF1chr151323601-LRRC7chr170257726+0.0028072040.9971928
ENST00000396153ENST00000035383FAF1chr151323601-LRRC7chr170257726+0.0003486110.99965143

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Fusion Genomic Features for FAF1-LRRC7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FAF1chr151323600-LRRC7chr170257725+5.92E-070.9999994
FAF1chr151323600-LRRC7chr170257725+5.92E-070.9999994

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FAF1-LRRC7


check button Go to

FGviewer for the breakpoints of chr1:51323601-chr1:70257726

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FAF1

Q9UNN5

LRRC7

Q8NAA5

FUNCTION: Ubiquitin-binding protein (PubMed:19722279). Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation (PubMed:26842564). Potentiates but cannot initiate FAS-induced apoptosis (By similarity). {ECO:0000250|UniProtKB:P54731, ECO:0000269|PubMed:19722279, ECO:0000269|PubMed:26842564}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLRRC7chr1:51323601chr1:70257726ENST000000353830251445_153563.01538.0DomainPDZ
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025116_13763.01538.0RepeatNote=LRR 5
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025139_16163.01538.0RepeatNote=LRR 6
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025162_18363.01538.0RepeatNote=LRR 7
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025185_20663.01538.0RepeatNote=LRR 8
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025208_22963.01538.0RepeatNote=LRR 9
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025231_25363.01538.0RepeatNote=LRR 10
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025254_27563.01538.0RepeatNote=LRR 11
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025277_29863.01538.0RepeatNote=LRR 12
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025300_32163.01538.0RepeatNote=LRR 13
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025323_34463.01538.0RepeatNote=LRR 14
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025346_36763.01538.0RepeatNote=LRR 15
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025369_39163.01538.0RepeatNote=LRR 16
TgeneLRRC7chr1:51323601chr1:70257726ENST00000035383025392_41363.01538.0RepeatNote=LRR 17
TgeneLRRC7chr1:51323601chr1:70257726ENST0000003538302570_9163.01538.0RepeatNote=LRR 3
TgeneLRRC7chr1:51323601chr1:70257726ENST0000003538302593_11463.01538.0RepeatNote=LRR 4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAF1chr1:51323601chr1:70257726ENST00000371778-3201_5738.0651.0DomainUBA
HgeneFAF1chr1:51323601chr1:70257726ENST00000371778-320569_64638.0651.0DomainUBX
HgeneFAF1chr1:51323601chr1:70257726ENST00000396153-2191_5738.0651.0DomainUBA
HgeneFAF1chr1:51323601chr1:70257726ENST00000396153-219569_64638.0651.0DomainUBX
TgeneLRRC7chr1:51323601chr1:70257726ENST0000003538302523_4463.01538.0RepeatNote=LRR 1
TgeneLRRC7chr1:51323601chr1:70257726ENST0000003538302547_6863.01538.0RepeatNote=LRR 2


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Fusion Gene Sequence for FAF1-LRRC7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000396153_ENST00000310961_TCGA-BH-A209-01A_FAF1_chr1_51323601_-_LRRC7_chr1_70257726_length(transcript)=6451nt_BP=566nt
AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC
CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC
ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC
ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC
GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG
CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGC
TTGAACAAAATAATTGGGACTTAGTGCAATTGTTCAACTGTCAAGCTCTACGAAAACTAAGTATTCCTGATAACGACCTTTCAAATCTGC
CAACCACTATTGCTAGTTTAGTTAATCTTAAAGAACTCGACATCAGTAAAAATGGTGTACAAGAATTTCCAGAAAACATAAAGTGCTGTA
AGTGTTTAACAATTATTGAAGCCAGTGTCAATCCCATTTCTAAACTACCTGATGGCTTCACACAGCTCCTAAACCTGACCCAGCTCTACC
TGAATGACGCCTTTCTTGAATTTCTTCCAGCCAATTTTGGAAGACTTGTCAAATTGCGGATCTTGGAGTTAAGAGAAAATCACTTGAAAA
CTCTACCAAAGTCAATGCACAAACTGGCCCAGTTGGAAAGACTTGACCTAGGCAATAATGAATTCGGTGAGCTGCCTGAAGTTCTGGATC
AAATACAAAATTTGAGGGAGTTATGGATGGATAATAATGCATTACAAGTGTTACCTGGGTCTATAGGGAAGTTAAAGATGTTGGTATACC
TGGATATGTCAAAAAACAGAATAGAAACAGTTGACATGGACATTTCTGGATGTGAAGCCCTTGAGGACCTCTTATTGTCATCCAATATGT
TGCAACAATTGCCTGATTCTATAGGACTTTTGAAAAAACTAACAACTCTAAAAGTAGATGACAATCAACTTACAATGCTACCCAATACAA
TTGGAAATTTATCTTTATTAGAAGAATTTGACTGTAGCTGTAATGAACTGGAGTCACTACCTTCTACTATTGGCTACCTTCATAGTCTTC
GGACATTAGCAGTTGATGAGAATTTCCTTCCAGAATTACCCAGAGAAATTGGAAGTTGTAAGAATGTAACAGTCATGTCTCTACGCTCCA
ACAAATTAGAATTTCTTCCTGAAGAGATTGGACAGATGCAGAAACTAAGAGTCCTAAATTTGAGTGACAACAGATTGAAGAATTTACCAT
TCTCATTTACCAAACTTAAAGAGCTTGCAGCTTTGTGGCTTTCTGACAATCAGTCCAAAGCCCTTATCCCTTTACAAACAGAAGCCCATC
CAGAAACAAAGCAAAGAGTATTGACTAACTACATGTTTCCCCAGCAGCCTCGTGGTGATGAAGATTTCCAGTCAGACAGTGACAGCTTTA
ACCCTACACTGTGGGAAGAGCAGAGACAACAACGCATGACTGTTGCCTTTGAATTTGAAGACAAAAAAGAAGATGACGAAAATGCTGGGA
AAGTTAAGGATCTCTCCTGCCAAGCCCCCTGGGAAAGGGGCCAGCGTGGGATTACTCTCCAACCTGCCAGACTGTCTGGCGATTGCTGCA
CACCATGGGCCAGGTGTGATCAGCAGATCCAAGATATGCCCGTCCCCCAGAATGACCCACAGCTGGCATGGGGTTGTATAAGTGGCCTCC
AGCAGGAAAGGAGCATGTGTACTCCATTGCCAGTTGCAGCACAATCCACCACTCTTCCCTCTCTAAGTGGCAGACAGGTTGAAATAAACC
TAAAACGATATCCAACTCCTTACCCAGAGGATTTAAAGAATATGGTAAAATCTGTTCAAAATTTGGTGGGTAAGCCAAGCCATGGAGTGC
GTGTTGAGAATTCAAATCCAACTGCTAACACGGAGCAAACTGTGAAAGAAAAATATGAACACAAGTGGCCGGTAGCCCCAAAGGAGATTA
CAGTGGAGGATTCTTTTGTTCATCCAGCTAATGAAATGAGGATTGGGGAACTTCACCCTTCATTAGCTGAGACCCCTCTGTACCCACCCA
AACTTGTTCTGCTAGGGAAGGACAAAAAAGAATCAACTGATGAGTCTGAAGTTGACAAAACTCACTGTCTGAATAACAGTGTTTCCTCAG
GCACTTACTCAGACTACTCGCCTTCCCAGGCTTCCTCAGGATCCTCTAATACCCGGGTTAAAGTGGGGTCCTTGCAGACAACAGCTAAAG
ATGCAGTACATAATTCTTTGTGGGGTAACAGGATTGCACCATCTTTCCCACAGCCTCTTGATTCAAAGCCATTACTCAGCCAGCGGGAGG
CTGTTCCCCCAGGCAATATACCACAGCGTCCTGACCGGCTGCCCATGAGTGATACTTTCACTGACAACTGGACTGATGGCTCGCATTATG
ACAACACAGGGTTTGTTGCTGAGGAAACCACAGCCGAGAATGCCAACAGTAATCCTCTCTTAAGTTCGAAATCTAGAAGCACATCTTCGC
ATGGACGCAGGCCTTTGATCAGGCAAGACAGGATTGTTGGTGTTCCCCTGGAACTCGAGCAGTCTACACACAGACACACACCAGAAACAG
AAGTGCCTCCTTCCAATCCTTGGCAGAATTGGACCAGAACCCCTAGTCCGTTTGAAGACAGGACCGCTTTTCCTTCCAAATTAGAGACAA
CCCCCACTACCAGCCCATTGCCTGAAAGGAAAGAACATATAAAGGAATCTACTGAAATACCTAGTCCTTTTTCTCCAGGCGTACCATGGG
AGTATCATGATTCCAATCCCAACAGGAGTCTTAGTAATGTCTTTTCTCAAATCCACTGCCGCCCGGAATCTTCTAAAGGTGTTATTTCAA
TTAGCAAAAGCACAGAGAGGCTTTCCCCCCTAATGAAAGATATCAAGTCTAATAAATTCAAAAAGTCACAGAGTATCGATGAGATTGACA
TTGGTACATATAAGGTGTATAACATACCATTAGAAAACTATGCTTCTGGGAGTGATCACTTAGGAAGCCACGAACGACCGGATAAGATGC
TGGGACCAGAGCATGGTATGTCCAGTATGTCTCGAAGCCAGTCAGTCCCAATGCTGGATGATGAGATGCTCACCTACGGAAGTAGTAAGG
GGCCACAACAACAAAAAGCTTCTATGACAAAAAAAGTCTATCAGTTTGACCAAAGCTTCAATCCTCAAGGATCAGTGGAAGTGAAAGCCG
AAAAGAGGATACCACCCCCTTTTCAACACAATCCCGAGTACGTGCAACAGGCCAGCAAAAACATCGCCAAGGATTTGATTAGTCCTAGAG
CTTACAGAGGATACCCACCGATGGAGCAAATGTTTTCATTTTCTCAGCCATCTGTGAATGAGGATGCTGTGGTGAATGCCCAGTTCGCAA
GCCAAGGGGCCAGGGCGGGCTTCCTGAGAAGGGCCGACTCCCTGGTGAGCGCCACAGAAATGGCCATGTTTAGAAGGGTCAATGAGCCTC
ATGAGCTGCCCCCAACTGATAGGTACGGCAGACCCCCATATAGGGGAGGGCTGGATCGCCAAAGCAGCGTTACAGTGACTGAGTCCCAGT
TCCTGAAAAGGAATGGCAGGTATGAAGATGAACACCCTTCATATCAAGAAGTGAAAGCTCAGGCGGGAAGTTTTCCGGTTAAAAACCTTA
CCCAAAGGAGGCCATTGTCTGCGAGAAGCTACAGTACAGAGAGTTACGGTGCCTCCCAAACCAGGCCAGTTTCAGCTAGGCCTACTATGG
CAGCTCTTTTGGAAAAAATACCATCTGACTATAACTTGGGTAACTATGGTGACAAGCCATCAGATAACAGTGATTTAAAGACGAGGCCTA
CTCCTGTGAAGGGAGAGGAGAGCTGTGGTAAAATGCCTGCAGACTGGAGACAACAGCTGCTTAGACATATAGAAGCTAGACGGTTAGACA
GGACCCCGTCCCAGCAAAGCAACATTTTAGACAATGGACAAGAAGATGTATCTCCTAGTGGCCAATGGAATCCTTATCCACTTGGGAGGC
GGGATGTACCTCCGGACACCATTACTAAGAAGGCAGGCAGCCACATCCAGACGTTGATGGGGTCCCAAAGCCTTCAGCATCGCAGCCGGG
AGCAGCAGCCGTATGAAGGAAATATAAACAAAGTGACCATCCAGCAATTTCAGTCACCATTGCCTATTCAGATCCCCTCTTCACAGGCCA
CCCGGGGACCTCAGCCTGGACGGTGCTTAATTCAAACTAAAGGGCAAAGGAGTATGGATGGATATCCAGAGCAGTTTTGTGTGAGAATAG
AAAAGAATCCTGGCCTTGGATTTAGTATCAGTGGTGGAATTAGTGGACAAGGAAATCCATTCAAACCTTCTGACAAGGGTATCTTTGTTA
CTAGGGTTCAGCCTGATGGGCCAGCATCAAACCTACTGCAGCCTGGTGATAAGATCCTTCAGGCAAATGGACACAGTTTTGTACATATGG
AACATGAAAAAGCTGTATTACTACTGAAGAGTTTCCAGAACACAGTAGACCTAGTTATTCAACGTGAGCTTACTGTCTAAATATTTTTTA
TAAATAGTGAAGATACGTCTAGCCAGACCTAATGTTCAAAAATAAATTTATACATAGAAACAAATTTTGCCAATTGCTGGACCAATGGCA
AACATTAGTGCCAAATGTATAATACTATATGTTAGCACTGACCATCCTTAAAAAATGTTAACTCTATAAATATGATGTTCATGTGGTTAT
GTATTAGTTTTAATTGTCAGCCTCTGGCTGTGCATTGGTGCAGTTTTGTTTCTGTTTTTGTTTTTGTTTTTAATCAAATAAGTTTCTTCT
CAAAATGGATTTCATATAATTTCGGAGCACGGAAGCACACACAAGCTCTTTATGAATTCTGCTCTCCATCAGAAACACTGCCTCAAAGTT
GTATATGCCTTTATATAGAAAATACAAATATAAAGAATTGTAATTCCCATAAAATATTTCTAGCACAAGGTATATGTTGGCATATATACA
AAAAGAATATAGAGAAAAACAATATTTTCATAAACTAAACATCTCAGATAGAGAAAAAATATATCTTAAAATAAGACTTTACTATATTGA
ATCTTTTTCAATAAAAATTACATGATAATGCCTTATGAAAGTAACTGTACATATGGTATAAAGTGTTTATATTTGGTTCCATATTCATTT
GCTAAATTCTCATGACACAGAGTGAAATATTTCATAAATTAGCCATTTATCTCTGGGACCCAAATAAAAATAGGATGAACTAATTTGTTC
AATGCCTTTAGCTAATTACAATACATGCAGAGTTTAGAAACAGACTAAAGGTCATTGTAGTTAAGTCTTTTTCACCACAAATTTAAGCAG
TGGATGATGGGTGGCAGGAAAGGTATTGCTTTATTTCTTTCAAGTTCATGTTGATTATAAACTGTAGCCCCTGTGATTTCTTTACTTGTA
AATGTGGAATTTATTTGTGTGTTGCTTAATCTAATTTGCTGCTTTTTAAATTATTTAAAACGAATTTTGGAAATTGATAAAATTTATCAT
TACGAAAGACTGCTGTTAGAAAGTTATGGTAGGTGATTTTAAATCCTTGGTATTTAAATATGAAACTTCAAATATAATTTCTCAGAGCTG
TGGTCTACCTGTATCATTAATTTCAATGGCTGTTTTTCTGGGCAGAAATAGATAAAATACTTTTTTTCCAAAAACAGTTTCAAGGTATGT
AAAATCCTGAATGCTTTTTCACTGAAGAGAAAGACAAGCATGGTTAATGTAGAATTATTTACTTTTCCATTGAAACTATTTTCCTGCATA
AATGATCAAAATTTATTTTATAATCCTTTAAAATACTTATCTTTCATATTAGTCATTAATTTAATTACAATATTAATTTGAATTTCCAGG
ATAATTTCCCGGAGTTGGTTGCATGCATTATCTTTCATAATTTTACATAGTTCTTTTGTTATATAATGAATTTACTTTACATGCTAGTGT
TTCAAGTATTGTATGAGGATTTTCACAATAGTATCACTGAATGATGTCACCAGAGCTCTGAGAATAATATTTGTAAGTTAACTGTTTTAT

>In-frame_ENST00000396153_ENST00000310961_TCGA-BH-A209-01A_FAF1_chr1_51323601_-_LRRC7_chr1_70257726_length(amino acids)=1569AA_start in transcript=140_stop in transcript=4849
MPSSWPATVRPDPHPDQSSCPGCCDAGSAGCRRAAGAPEGYRVHERLALPALPRPLARRPARRLARQPLGARRRRRRWRRRSQEVPSASQ
VRASLPEPRNSAAAMASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISK
NGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDL
GNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL
KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLR
VLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAF
EFEDKKEDDENAGKVKDLSCQAPWERGQRGITLQPARLSGDCCTPWARCDQQIQDMPVPQNDPQLAWGCISGLQQERSMCTPLPVAAQST
TLPSLSGRQVEINLKRYPTPYPEDLKNMVKSVQNLVGKPSHGVRVENSNPTANTEQTVKEKYEHKWPVAPKEITVEDSFVHPANEMRIGE
LHPSLAETPLYPPKLVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSGSSNTRVKVGSLQTTAKDAVHNSLWGNRIAPSFP
QPLDSKPLLSQREAVPPGNIPQRPDRLPMSDTFTDNWTDGSHYDNTGFVAEETTAENANSNPLLSSKSRSTSSHGRRPLIRQDRIVGVPL
ELEQSTHRHTPETEVPPSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKEHIKESTEIPSPFSPGVPWEYHDSNPNRSLSNVFSQ
IHCRPESSKGVISISKSTERLSPLMKDIKSNKFKKSQSIDEIDIGTYKVYNIPLENYASGSDHLGSHERPDKMLGPEHGMSSMSRSQSVP
MLDDEMLTYGSSKGPQQQKASMTKKVYQFDQSFNPQGSVEVKAEKRIPPPFQHNPEYVQQASKNIAKDLISPRAYRGYPPMEQMFSFSQP
SVNEDAVVNAQFASQGARAGFLRRADSLVSATEMAMFRRVNEPHELPPTDRYGRPPYRGGLDRQSSVTVTESQFLKRNGRYEDEHPSYQE
VKAQAGSFPVKNLTQRRPLSARSYSTESYGASQTRPVSARPTMAALLEKIPSDYNLGNYGDKPSDNSDLKTRPTPVKGEESCGKMPADWR
QQLLRHIEARRLDRTPSQQSNILDNGQEDVSPSGQWNPYPLGRRDVPPDTITKKAGSHIQTLMGSQSLQHRSREQQPYEGNINKVTIQQF
QSPLPIQIPSSQATRGPQPGRCLIQTKGQRSMDGYPEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASNLLQPGD

--------------------------------------------------------------
>In-frame_ENST00000396153_ENST00000370958_TCGA-BH-A209-01A_FAF1_chr1_51323601_-_LRRC7_chr1_70257726_length(transcript)=2448nt_BP=566nt
AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC
CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC
ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC
ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC
GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG
CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGC
TTGAACAAAATAATTGGGACTTAGTGCAATTGTTCAACTGTCAAGCTCTACGAAAACTAAGTATTCCTGATAACGACCTTTCAAATCTGC
CAACCACTATTGCTAGTTTAGTTAATCTTAAAGAACTCGACATCAGTAAAAATGGTGTACAAGAATTTCCAGAAAACATAAAGTGCTGTA
AGTGTTTAACAATTATTGAAGCCAGTGTCAATCCCATTTCTAAACTACCTGATGGCTTCACACAGCTCCTAAACCTGACCCAGCTCTACC
TGAATGACGCCTTTCTTGAATTTCTTCCAGCCAATTTTGGAAGACTTGTCAAATTGCGGATCTTGGAGTTAAGAGAAAATCACTTGAAAA
CTCTACCAAACATCTGAAGATCCAGAGTGTGCCCCTTGCCCAATCGCCTGAGACTATACAGTGACACCTACAACAGAGGATGTGGAGGGA
GCAGCTTTTCGGGCACCAGAAATGGCAGCATCAGGAGCATCAGCACGAATAGACTTTGTAGAGGTAGTTCTCCCAAACTATATTATGAAA
CCAAACATTTTTGGTGCGCTACCTGCTGATGGGGGCTGCCTTCTTACTGCCTAGTATCTACAAAATGTTTGGTCTTTGTTAAAGTTTAAC
GATGACATTTCTGACTAATATAGAGAGACCTGATTTTTTTCCAAATGTGTTCAGTTGCCATAACTTTCAATGAATATGAAATTTTATCAG
TCTCAGAAAAACATTAATACCCATATTTTTATCTAATTGATTTCACTATTTGTTATGTTAAGGTGCTTTTGTGTATAATTTTTGTATATA
TTTTTAAATGGGATCAAACTAAGCCATAATTTAAAAGTCATCCTAATGCAGTAAATAAGATAATTTCTCTAGTTTGTTAAATTCTTCAGA
GACCGAATATAATTGCTCGTTTTTCTGTCATACTCCCTGATGATGTTCCATTGTGGACTTATTTTGCAAAGTTCCCAGATGGCACAAGTC
AAAATATGAAATGCTGATGATTGATTGATTTTATGTATCCTTTCATCTTATGTAATTTAATGTGGAACAGTTATTTTGTAGCTCTAAAAT
ACATTTGTTAATTAACCATATTGGCTTTTCATGCAGTTCAATGGCTTATAGCATTTCAATTTGCATAGAAAATGAATCTCTGTAATGATA
CTTTTGCTAAATAAATAACAATCGACATAATGGGTTCATTTGCTTTTAACATTTTATACATACAATTTAGAAGTAGGATATATTTCATAT
TGAAATTTTGAAAAGCTTGAAATTCAACATACAAGGTCACCATCTTGCTGATGCCTAATGCAGTACAGCAAATTCATTCTTCATCCCATG
TTAACTCCTTTTTGGAACAAGTCAAAATACAAATAATTTACAATGATTGTGTTGGAGCTATTGCTTGATTAAATACAATTCAAAGGTTCT
TTTTATAAAACAGGTGTGAGCAGGACACATTGCACTTACGGGCTTTTCCTATTTTTTTGGTTCTATTTCATTTTACTGCCTAGGAAAGAA
ACATTTTTTTGTAAAACCTATGCTATGGAACTGAAATGTACTTTATTGAATATTTCTATTCTGTTTTATGAATATCAATTATGTGAAATA
TATAAATATAAAATTGCCTTAGAATGCCTAACTCTTTGTATAAAACAGATATCTGAAAGTAGATGTTGGTTTTTTGTTCAAATTGTGTAA
ATGCTGATTTTTCCATGAGTACTTATGAAGATCTATATGTAAAAATTTTAAGTCTGCTTACTGTGTTTGTACCACCTTGTTCTTAGCTGT
GTATACTCTATGCTAATTGACTTCTGTCATTGTCACATATATTGCATATGTCTCTCAAAAATTAAAAGGTATATTGCTATTCTAAAAATA

>In-frame_ENST00000396153_ENST00000370958_TCGA-BH-A209-01A_FAF1_chr1_51323601_-_LRRC7_chr1_70257726_length(amino acids)=258AA_start in transcript=140_stop in transcript=916
MPSSWPATVRPDPHPDQSSCPGCCDAGSAGCRRAAGAPEGYRVHERLALPALPRPLARRPARRLARQPLGARRRRRRWRRRSQEVPSASQ
VRASLPEPRNSAAAMASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISK

--------------------------------------------------------------
>In-frame_ENST00000396153_ENST00000035383_TCGA-BH-A209-01A_FAF1_chr1_51323601_-_LRRC7_chr1_70257726_length(transcript)=5347nt_BP=566nt
AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC
CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC
ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC
ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC
GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG
CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGC
TTGAACAAAATAATTGGGACTTAGTGCAATTGTTCAACTGTCAAGCTCTACGAAAACTAAGTATTCCTGATAACGACCTTTCAAATCTGC
CAACCACTATTGCTAGTTTAGTTAATCTTAAAGAACTCGACATCAGTAAAAATGGTGTACAAGAATTTCCAGAAAACATAAAGTGCTGTA
AGTGTTTAACAATTATTGAAGCCAGTGTCAATCCCATTTCTAAACTACCTGATGGCTTCACACAGCTCCTAAACCTGACCCAGCTCTACC
TGAATGACGCCTTTCTTGAATTTCTTCCAGCCAATTTTGGAAGACTTGTCAAATTGCGGATCTTGGAGTTAAGAGAAAATCACTTGAAAA
CTCTACCAAAGTCAATGCACAAACTGGCCCAGTTGGAAAGACTTGACCTAGGCAATAATGAATTCGGTGAGCTGCCTGAAGTTCTGGATC
AAATACAAAATTTGAGGGAGTTATGGATGGATAATAATGCATTACAAGTGTTACCTGGGTCTATAGGGAAGTTAAAGATGTTGGTATACC
TGGATATGTCAAAAAACAGAATAGAAACAGTTGACATGGACATTTCTGGATGTGAAGCCCTTGAGGACCTCTTATTGTCATCCAATATGT
TGCAACAATTGCCTGATTCTATAGGACTTTTGAAAAAACTAACAACTCTAAAAGTAGATGACAATCAACTTACAATGCTACCCAATACAA
TTGGAAATTTATCTTTATTAGAAGAATTTGACTGTAGCTGTAATGAACTGGAGTCACTACCTTCTACTATTGGCTACCTTCATAGTCTTC
GGACATTAGCAGTTGATGAGAATTTCCTTCCAGAATTACCCAGAGAAATTGGAAGTTGTAAGAATGTAACAGTCATGTCTCTACGCTCCA
ACAAATTAGAATTTCTTCCTGAAGAGATTGGACAGATGCAGAAACTAAGAGTCCTAAATTTGAGTGACAACAGATTGAAGAATTTACCAT
TCTCATTTACCAAACTTAAAGAGCTTGCAGCTTTGTGGCTTTCTGACAATCAGTCCAAAGCCCTTATCCCTTTACAAACAGAAGCCCATC
CAGAAACAAAGCAAAGAGTATTGACTAACTACATGTTTCCCCAGCAGCCTCGTGGTGATGAAGATTTCCAGTCAGACAGTGACAGCTTTA
ACCCTACACTGTGGGAAGAGCAGAGACAACAACGCATGACTGTTGCCTTTGAATTTGAAGACAAAAAAGAAGATGACGAAAATGCTGGGA
AAGTTAAGGATCTCTCCTGCCAAGCCCCCTGGGAAAGGGGCCAGCGTGGGATTACTCTCCAACCTGCCAGACTGTCTGGCGATTGCTGCA
CACCATGGGCCAGGTGTGATCAGCAGATCCAAGATATGCCCGTCCCCCAGAATGACCCACAGCTGGCATGGGGTTGTATAAGTGGCCTCC
AGCAGGAAAGGAGCATGTGTACTCCATTGCCAGTTGCAGCACAATCCACCACTCTTCCCTCTCTAAGTGGCAGACAGGTTGAAATAAACC
TAAAACGATATCCAACTCCTTACCCAGAGGATTTAAAGAATATGGTAAAATCTGTTCAAAATTTGGTGGGTAAGCCAAGCCATGGAGTGC
GTGTTGAGAATTCAAATCCAACTGCTAACACGGAGCAAACTGTGAAAGAAAAATATGAACACAAGTGGCCGGTAGCCCCAAAGGAGATTA
CAGTGGAGGATTCTTTTGTTCATCCAGCTAATGAAATGAGGATTGGGGAACTTCACCCTTCATTAGCTGAGACCCCTCTGTACCCACCCA
AACTTGTTCTGCTAGGGAAGGACAAAAAAGAATCAACTGATGAGTCTGAAGTTGACAAAACTCACTGTCTGAATAACAGTGTTTCCTCAG
GCACTTACTCAGACTACTCGCCTTCCCAGGCTTCCTCAGGATCCTCTAATACCCGGGTTAAAGTGGGGTCCTTGCAGACAACAGCTAAAG
ATGCAGTACATAATTCTTTGTGGGGTAACAGGATTGCACCATCTTTCCCACAGCCTCTTGATTCAAAGCCATTACTCAGCCAGCGGGAGG
CTGTTCCCCCAGGCAATATACCACAGCGTCCTGACCGGCTGCCCATGAGTGATACTTTCACTGACAACTGGACTGATGGCTCGCATTATG
ACAACACAGGGTTTGTTGCTGAGGAAACCACAGCCGAGAATGCCAACAGTAATCCTCTCTTAAGTTCGAAATCTAGAAGCACATCTTCGC
ATGGACGCAGGCCTTTGATCAGGCAAGACAGGATTGTTGGTGTTCCCCTGGAACTCGAGCAGTCTACACACAGACACACACCAGAAACAG
AAGTGCCTCCTTCCAATCCTTGGCAGAATTGGACCAGAACCCCTAGTCCGTTTGAAGACAGGACCGCTTTTCCTTCCAAATTAGAGACAA
CCCCCACTACCAGCCCATTGCCTGAAAGGAAAGAACATATAAAGGAATCTACTGAAATACCTAGTCCTTTTTCTCCAGGCGTACCATGGG
AGTATCATGATTCCAATCCCAACAGGAGTCTTAGTAATGTCTTTTCTCAAATCCACTGCCGCCCGGAATCTTCTAAAGGTGTTATTTCAA
TTAGCAAAAGCACAGAGAGGCTTTCCCCCCTAATGAAAGATATCAAGTCTAATAAATTCAAAAAGTCACAGAGTATCGATGAGATTGACA
TTGGTACATATAAGGTGTATAACATACCATTAGAAAACTATGCTTCTGGGAGTGATCACTTAGGAAGCCACGAACGACCGGATAAGATGC
TGGGACCAGAGCATGGTATGTCCAGTATGTCTCGAAGCCAGTCAGTCCCAATGCTGGATGATGAGATGCTCACCTACGGAAGTAGTAAGG
GGCCACAACAACAAAAAGCTTCTATGACAAAAAAAGTCTATCAGTTTGACCAAAGCTTCAATCCTCAAGGATCAGTGGAAGTGAAAGCCG
AAAAGAGGATACCACCCCCTTTTCAACACAATCCCGAGTACGTGCAACAGGCCAGCAAAAACATCGCCAAGGATTTGATTAGTCCTAGAG
CTTACAGAGGATACCCACCGATGGAGCAAATGTTTTCATTTTCTCAGCCATCTGTGAATGAGGATGCTGTGGTGAATGCCCAGTTCGCAA
GCCAAGGGGCCAGGGCGGGCTTCCTGAGAAGGGCCGACTCCCTGGTGAGCGCCACAGAAATGGCCATGTTTAGAAGGGTCAATGAGCCTC
ATGAGCTGCCCCCAACTGATAGGTACGGCAGACCCCCATATAGGGGAGGGCTGGATCGCCAAAGCAGCGTTACAGTGACTGAGTCCCAGT
TCCTGAAAAGGAATGGCAGGTATGAAGATGAACACCCTTCATATCAAGAAGTGAAAGCTCAGGCGGGAAGTTTTCCGGTTAAAAACCTTA
CCCAAAGGAGGCCATTGTCTGCGAGAAGCTACAGTACAGAGAGTTACGGTGCCTCCCAAACCAGGCCAGTTTCAGCTAGGCCTACTATGG
CAGCTCTTTTGGAAAAAATACCATCTGACTATAACTTGGGTAACTATGGTGACAAGCCATCAGATAACAGTGATTTAAAGACGAGGCCTA
CTCCTGTGAAGGGAGAGGAGAGCTGTGGTAAAATGCCTGCAGACTGGAGACAACAGCTGCTTAGACATATAGAAGCTAGACGGTTAGACA
GGAATGCTGCTTACAAACACAATACAGTTAACCTTGGCATGCTGCCCTATGGAGGTATTTCAGCAATGCATGCAGGCAGAAGCATGACTT
TAAACTTGCAGACTAAGTCTAAATTTGATCATCAAGAACTACCTCTTCAGAAAACCCCGTCCCAGCAAAGCAACATTTTAGACAATGGAC
AAGAAGATGTATCTCCTAGTGGCCAATGGAATCCTTATCCACTTGGGAGGCGGGATGTACCTCCGGACACCATTACTAAGAAGGCAGGCA
GCCACATCCAGACGTTGATGGGGTCCCAAAGCCTTCAGCATCGCAGCCGGGAGCAGCAGCCGTATGAAGGAAATATAAACAAAGTGACCA
TCCAGCAATTTCAGTCACCATTGCCTATTCAGATCCCCTCTTCACAGGCCACCCGGGGACCTCAGCCTGGACGGTGCTTAATTCAAACTA
AAGGGCAAAGGAGTATGGATGGATATCCAGAGCAGTTTTGTGTGAGAATAGAAAAGAATCCTGGCCTTGGATTTAGTATCAGTGGTGGAA
TTAGTGGACAAGGAAATCCATTCAAACCTTCTGACAAGGGTATCTTTGTTACTAGGGTTCAGCCTGATGGGCCAGCATCAAACCTACTGC
AGCCTGGTGATAAGATCCTTCAGGCAAATGGACACAGTTTTGTACATATGGAACATGAAAAAGCTGTATTACTACTGAAGAGTTTCCAGA
ACACAGTAGACCTAGTTATTCAACGTGAGCTTACTGTCTAAATATTTTTTATAAATAGTGAAGATACGTCTAGCCAGACCTAATGTTCAA
AAATAAATTTATACATAGAAACAAATTTTGCCAATTGCTGGACCAATGGCAAACATTAGTGCCAAATGTATAATACTATATGTTAGCACT
GACCATCCTTAAAAAATGTTAACTCTATAAATATGATGTTCATGTGGTTATGTATTAGTTTTAATTGTCAGCCTCTGGCTGTGCATTGGT
GCAGTTTTGTTTCTGTTTTTGTTTTTGTTTTTAATCAAATAAGTTTCTTCTCAAAATGGATTTCATATAATTTCGGAGCACGGAAGCACA

>In-frame_ENST00000396153_ENST00000035383_TCGA-BH-A209-01A_FAF1_chr1_51323601_-_LRRC7_chr1_70257726_length(amino acids)=1616AA_start in transcript=140_stop in transcript=4990
MPSSWPATVRPDPHPDQSSCPGCCDAGSAGCRRAAGAPEGYRVHERLALPALPRPLARRPARRLARQPLGARRRRRRWRRRSQEVPSASQ
VRASLPEPRNSAAAMASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISK
NGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDL
GNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL
KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLR
VLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAF
EFEDKKEDDENAGKVKDLSCQAPWERGQRGITLQPARLSGDCCTPWARCDQQIQDMPVPQNDPQLAWGCISGLQQERSMCTPLPVAAQST
TLPSLSGRQVEINLKRYPTPYPEDLKNMVKSVQNLVGKPSHGVRVENSNPTANTEQTVKEKYEHKWPVAPKEITVEDSFVHPANEMRIGE
LHPSLAETPLYPPKLVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSGSSNTRVKVGSLQTTAKDAVHNSLWGNRIAPSFP
QPLDSKPLLSQREAVPPGNIPQRPDRLPMSDTFTDNWTDGSHYDNTGFVAEETTAENANSNPLLSSKSRSTSSHGRRPLIRQDRIVGVPL
ELEQSTHRHTPETEVPPSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKEHIKESTEIPSPFSPGVPWEYHDSNPNRSLSNVFSQ
IHCRPESSKGVISISKSTERLSPLMKDIKSNKFKKSQSIDEIDIGTYKVYNIPLENYASGSDHLGSHERPDKMLGPEHGMSSMSRSQSVP
MLDDEMLTYGSSKGPQQQKASMTKKVYQFDQSFNPQGSVEVKAEKRIPPPFQHNPEYVQQASKNIAKDLISPRAYRGYPPMEQMFSFSQP
SVNEDAVVNAQFASQGARAGFLRRADSLVSATEMAMFRRVNEPHELPPTDRYGRPPYRGGLDRQSSVTVTESQFLKRNGRYEDEHPSYQE
VKAQAGSFPVKNLTQRRPLSARSYSTESYGASQTRPVSARPTMAALLEKIPSDYNLGNYGDKPSDNSDLKTRPTPVKGEESCGKMPADWR
QQLLRHIEARRLDRNAAYKHNTVNLGMLPYGGISAMHAGRSMTLNLQTKSKFDHQELPLQKTPSQQSNILDNGQEDVSPSGQWNPYPLGR
RDVPPDTITKKAGSHIQTLMGSQSLQHRSREQQPYEGNINKVTIQQFQSPLPIQIPSSQATRGPQPGRCLIQTKGQRSMDGYPEQFCVRI

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Fusion Gene PPI Analysis for FAF1-LRRC7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FAF1-LRRC7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FAF1-LRRC7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneLRRC7C0009171Cocaine Abuse1CTD_human
TgeneLRRC7C0236736Cocaine-Related Disorders1CTD_human
TgeneLRRC7C0600427Cocaine Dependence1CTD_human