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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AGAP1-ATG4B (FusionGDB2 ID:2874)

Fusion Gene Summary for AGAP1-ATG4B

check button Fusion gene summary
Fusion gene informationFusion gene name: AGAP1-ATG4B
Fusion gene ID: 2874
HgeneTgene
Gene symbol

AGAP1

ATG4B

Gene ID

116987

23192

Gene nameArfGAP with GTPase domain, ankyrin repeat and PH domain 1autophagy related 4B cysteine peptidase
SynonymsAGAP-1|CENTG2|GGAP1|cnt-g2APG4B|AUTL1
Cytomap

2q37.2

2q37.3

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with GTPase, ANK repeat and PH domain-containing protein 1Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1GTP-binding and GTPase-activating protein 1centaurin, gamma 2cysteine protease ATG4BAPG4 autophagy 4 homolog BATG4 autophagy related 4 homolog BAUT-like 1 cysteine endopeptidaseautophagin-1autophagy-related cysteine endopeptidase 1autophagy-related protein 4 homolog BhAPG4B
Modification date2020031320200329
UniProtAcc

Q9UPQ3

Q9Y4P1

Ensembl transtripts involved in fusion geneENST00000336665, ENST00000304032, 
ENST00000409538, ENST00000428334, 
ENST00000409457, 		ENST00000405546, 
ENST00000402096, ENST00000404914, 
ENST00000491867, ENST00000396411, 
ENST00000474739, 
Fusion gene scores* DoF score49 X 18 X 17=149944 X 4 X 3=48
# samples 485
** MAII scorelog2(48/14994*10)=-4.96520709119934
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/48*10)=0.0588936890535686
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: AGAP1 [Title/Abstract] AND ATG4B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAGAP1(236403493)-ATG4B(242590425), # samples:4
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneATG4B

GO:0006508

proteolysis

15169837|18387192

TgeneATG4B

GO:0006914

autophagy

18387192

TgeneATG4B

GO:0051697

protein delipidation

25327288


check buttonFusion gene breakpoints across AGAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ATG4B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A3U7-01AAGAP1chr2

236403493

+ATG4Bchr2

242590425

+
ChimerDB4SARCTCGA-DX-A3U7AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
ChimerDB4SARCTCGA-DX-A3U7-01AAGAP1chr2

236403493

+ATG4Bchr2

242590425

+
ChimerDB4SARCTCGA-3B-A9HT-01AAGAP1chr2

236403493

+ATG4Bchr2

242590425

+
ChimerDB4SARCTCGA-DX-A3U7-01AAGAP1chr2

236403493

-ATG4Bchr2

242590425

+


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Fusion Gene ORF analysis for AGAP1-ATG4B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000336665ENST00000405546AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000336665ENST00000402096AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000336665ENST00000404914AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-3UTRENST00000336665ENST00000491867AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000336665ENST00000396411AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000336665ENST00000474739AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
In-frameENST00000304032ENST00000405546AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000304032ENST00000402096AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000304032ENST00000404914AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-3UTRENST00000304032ENST00000491867AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000304032ENST00000396411AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000304032ENST00000474739AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-3CDSENST00000409538ENST00000405546AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-5UTRENST00000409538ENST00000402096AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-5UTRENST00000409538ENST00000404914AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-3UTRENST00000409538ENST00000491867AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-5UTRENST00000409538ENST00000396411AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-5UTRENST00000409538ENST00000474739AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-3CDSENST00000428334ENST00000405546AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-5UTRENST00000428334ENST00000402096AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-5UTRENST00000428334ENST00000404914AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-3UTRENST00000428334ENST00000491867AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-5UTRENST00000428334ENST00000396411AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
intron-5UTRENST00000428334ENST00000474739AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
In-frameENST00000409457ENST00000405546AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000409457ENST00000402096AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000409457ENST00000404914AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-3UTRENST00000409457ENST00000491867AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000409457ENST00000396411AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
5CDS-5UTRENST00000409457ENST00000474739AGAP1chr2

236403493

+ATG4Bchr2

242590425

+
In-frameENST00000336665ENST00000405546AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000336665ENST00000402096AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000336665ENST00000404914AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-3UTRENST00000336665ENST00000491867AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000336665ENST00000396411AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000336665ENST00000474739AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
In-frameENST00000304032ENST00000405546AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000304032ENST00000402096AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000304032ENST00000404914AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-3UTRENST00000304032ENST00000491867AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000304032ENST00000396411AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000304032ENST00000474739AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-3CDSENST00000409538ENST00000405546AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-5UTRENST00000409538ENST00000402096AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-5UTRENST00000409538ENST00000404914AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-3UTRENST00000409538ENST00000491867AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-5UTRENST00000409538ENST00000396411AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-5UTRENST00000409538ENST00000474739AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-3CDSENST00000428334ENST00000405546AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-5UTRENST00000428334ENST00000402096AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-5UTRENST00000428334ENST00000404914AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-3UTRENST00000428334ENST00000491867AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-5UTRENST00000428334ENST00000396411AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
intron-5UTRENST00000428334ENST00000474739AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
In-frameENST00000409457ENST00000405546AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000409457ENST00000402096AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000409457ENST00000404914AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-3UTRENST00000409457ENST00000491867AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000409457ENST00000396411AGAP1chr2

236403493

+ATG4Bchr2

242590424

+
5CDS-5UTRENST00000409457ENST00000474739AGAP1chr2

236403493

+ATG4Bchr2

242590424

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000336665AGAP1chr2236403493+ENST00000405546ATG4Bchr2242590425+35257434211875484
ENST00000304032AGAP1chr2236403493+ENST00000405546ATG4Bchr2242590425+35257434211875484
ENST00000409457AGAP1chr2236403493+ENST00000405546ATG4Bchr2242590425+35437614391893484
ENST00000336665AGAP1chr2236403493+ENST00000405546ATG4Bchr2242590424+35257434211875484
ENST00000304032AGAP1chr2236403493+ENST00000405546ATG4Bchr2242590424+35257434211875484
ENST00000409457AGAP1chr2236403493+ENST00000405546ATG4Bchr2242590424+35437614391893484

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000336665ENST00000405546AGAP1chr2236403493+ATG4Bchr2242590425+0.0024524010.99754757
ENST00000304032ENST00000405546AGAP1chr2236403493+ATG4Bchr2242590425+0.0024524010.99754757
ENST00000409457ENST00000405546AGAP1chr2236403493+ATG4Bchr2242590425+0.0025200010.99748
ENST00000336665ENST00000405546AGAP1chr2236403493+ATG4Bchr2242590424+0.0024524010.99754757
ENST00000304032ENST00000405546AGAP1chr2236403493+ATG4Bchr2242590424+0.0024524010.99754757
ENST00000409457ENST00000405546AGAP1chr2236403493+ATG4Bchr2242590424+0.0025200010.99748

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Fusion Genomic Features for AGAP1-ATG4B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
AGAP1chr2236403493+ATG4Bchr2242590424+2.48E-081
AGAP1chr2236403493+ATG4Bchr2242590424+2.48E-081
AGAP1chr2236403493+ATG4Bchr2242590424+2.48E-081
AGAP1chr2236403493+ATG4Bchr2242590424+2.48E-081
AGAP1chr2236403493+ATG4Bchr2242590424+2.48E-081
AGAP1chr2236403493+ATG4Bchr2242590424+2.48E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for AGAP1-ATG4B


check button Go to

FGviewer for the breakpoints of chr2:236403493-chr2:242590425

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AGAP1

Q9UPQ3

ATG4B

Q9Y4P1

FUNCTION: GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system. {ECO:0000269|PubMed:12640130}.FUNCTION: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. {ECO:0000269|PubMed:15169837, ECO:0000269|PubMed:15187094, ECO:0000269|PubMed:17347651, ECO:0000269|PubMed:19322194, ECO:0000269|PubMed:21177865, ECO:0000269|PubMed:22302004}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGAP1chr2:236403493chr2:242590424ENST00000304032+118346_58854.333333333333336858.0DomainPH
HgeneAGAP1chr2:236403493chr2:242590424ENST00000304032+118609_72954.333333333333336858.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000336665+117346_58854.333333333333336805.0DomainPH
HgeneAGAP1chr2:236403493chr2:242590424ENST00000336665+117609_72954.333333333333336805.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000409457+110346_58854.333333333333336406.0DomainPH
HgeneAGAP1chr2:236403493chr2:242590424ENST00000409457+110609_72954.333333333333336406.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000304032+118346_58854.333333333333336858.0DomainPH
HgeneAGAP1chr2:236403493chr2:242590425ENST00000304032+118609_72954.333333333333336858.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000336665+117346_58854.333333333333336805.0DomainPH
HgeneAGAP1chr2:236403493chr2:242590425ENST00000336665+117609_72954.333333333333336805.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000409457+110346_58854.333333333333336406.0DomainPH
HgeneAGAP1chr2:236403493chr2:242590425ENST00000409457+110609_72954.333333333333336406.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000304032+118122_12654.333333333333336858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000304032+118178_18154.333333333333336858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000304032+11878_8554.333333333333336858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000336665+117122_12654.333333333333336805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000336665+117178_18154.333333333333336805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000336665+11778_8554.333333333333336805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000409457+110122_12654.333333333333336406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000409457+110178_18154.333333333333336406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000409457+11078_8554.333333333333336406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000304032+118122_12654.333333333333336858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000304032+118178_18154.333333333333336858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000304032+11878_8554.333333333333336858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000336665+117122_12654.333333333333336805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000336665+117178_18154.333333333333336805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000336665+11778_8554.333333333333336805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000409457+110122_12654.333333333333336406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000409457+110178_18154.333333333333336406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590425ENST00000409457+11078_8554.333333333333336406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:242590424ENST00000304032+11866_27654.333333333333336858.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr2:242590424ENST00000336665+11766_27654.333333333333336805.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr2:242590424ENST00000409457+11066_27654.333333333333336406.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr2:242590425ENST00000304032+11866_27654.333333333333336858.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr2:242590425ENST00000336665+11766_27654.333333333333336805.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr2:242590425ENST00000409457+11066_27654.333333333333336406.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr2:242590424ENST00000304032+118768_79754.333333333333336858.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr2:242590424ENST00000304032+118801_83054.333333333333336858.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr2:242590424ENST00000336665+117768_79754.333333333333336805.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr2:242590424ENST00000336665+117801_83054.333333333333336805.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr2:242590424ENST00000409457+110768_79754.333333333333336406.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr2:242590424ENST00000409457+110801_83054.333333333333336406.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr2:242590425ENST00000304032+118768_79754.333333333333336858.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr2:242590425ENST00000304032+118801_83054.333333333333336858.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr2:242590425ENST00000336665+117768_79754.333333333333336805.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr2:242590425ENST00000336665+117801_83054.333333333333336805.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr2:242590425ENST00000409457+110768_79754.333333333333336406.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr2:242590425ENST00000409457+110801_83054.333333333333336406.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr2:242590424ENST00000304032+118624_64754.333333333333336858.0Zinc fingerC4-type
HgeneAGAP1chr2:236403493chr2:242590424ENST00000336665+117624_64754.333333333333336805.0Zinc fingerC4-type
HgeneAGAP1chr2:236403493chr2:242590424ENST00000409457+110624_64754.333333333333336406.0Zinc fingerC4-type
HgeneAGAP1chr2:236403493chr2:242590425ENST00000304032+118624_64754.333333333333336858.0Zinc fingerC4-type
HgeneAGAP1chr2:236403493chr2:242590425ENST00000336665+117624_64754.333333333333336805.0Zinc fingerC4-type
HgeneAGAP1chr2:236403493chr2:242590425ENST00000409457+110624_64754.333333333333336406.0Zinc fingerC4-type


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Fusion Gene Sequence for AGAP1-ATG4B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000336665_ENST00000405546_TCGA-DX-A3U7-01A_AGAP1_chr2_236403493_+_ATG4B_chr2_242590425_length(transcript)=3525nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGACACTCTCCGGTTTGCTGAGTTTGAAGATTTTCCTGAGACCTCAGAGCCCGT
TTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAGGACGAGATCTTGTCTGATGTGGCATCTAGACTTTGGTTTACATACAGGAA
AAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGACACAGGCTGGGGCTGCATGCTGCGGTGTGGACAGATGATCTTTGCCCAAGC
CCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACACAAAGGAAGAGGCAGCCAGACAGCTACTTCAGCGTCCTCAACGCATTCAT
CGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCGCAAATGGGAGTTGGCGAAGGCAAGTCCATAGGCCAGTGGTACGGGCCCAA
CACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGATACGTGGAGCTCCTTGGCGGTCCACATTGCAATGGACAACACTGTTGTGAT
GGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGTGCAGGCGCCACTGCGTTTCCTGCAGATTCCGACCGGCACTGCAACGGATT
CCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGACCCCTGGTACTTCTCATTCCCCTGCGCCTGGGGCTCACGGACATCAA
CGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATGCCCCAGTCCCTGGGCGTCATCGGAGGGAAGCCCAACAGCGCCCACTACTT
CATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCCCACACCACGCAGCCAGCCGTGGAGCCCACTGATGGCTGCTTCATCCCGGA
CGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGCATCGCGGAGCTTGACCCGTCCATCGCTGTGGGGTTTTTCTGTAAGACTGA
AGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTGTCTCTGCTTGGAGGTGCCCTGCCCATGTTTGAGCTGGTGGAGCTGCAGCC
TTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTAGGTGAGAGCTGCCAAGTCCAGATTCTTCTGATGTAGAGCGACTGGAAAGA
TTCTTCGACTCAGAAGATGAAGACTTTGAAATCCTGTCCCTTTGAAAATCCTGGGGTCGGGGGTGGCACCTGTGAGAGCCTGGGGCTCCT
GGTGCCGCTGCGTTTCATCCATCCCGCCCGCTCGCCTGCCGAGGGCTGCGCCCCGTGCTGCCTCCCCCCAGAGGGCCACCCGCTGTGCTC
GTGGACTGAGGCTGCGCTGCCCGGGAGGCCTTACTGCTTGGTGTCAGACTGCCCAGCTCAGAGTGCCCGTCAGGGCCTGTGCATCCGCAC
GCGGAGCCGTCTGTTAGGAGCTTCCAGAGTGTTCTCTCGACACTGCCAGCCCCGTGTTAGCACCTGGGCCTCAGTCCCACTTGCTCCCAG
GCGCCGGTTCTGTGGTTGGTTTGGAATTAAAGTCCTGTTTGAAGTTGTCAGACACAGACATGAATTTCTGGGCGCTCCCTGAGTCAGAGT
CTCAGAAGACCTGTGCAGGCTGGCGTGAGAGGAGCGGCAGCCACACTGCGGCCCCACGCCCAAGGACTGGGCTGCTCTCGAGGGGGGCGC
GCCCACCGCTGTGTCCTCTCTGCCCAGCCTGGCTTACCAAGGGCTACCTCAGTGGGAGATGAGGTTGGAGGAACGAAGGCGAGGTTCCTC
CTTGCTTTGGGGAGAAAAGTATTCAGGAAGTGGGTGTGTGGGAAACCTGAAGATGGCGTGCACAGGACACAGCGTGGGCGGCCTGGGCAG
AAGGGCGGCTGGCTGTCCTGGAGCTGCTGCTGGAGCCTGCCCTCAGAGTGTCCCTTTCCAGTGCTGTGGCATTCTGTGGCAGCTTCCCCA
GGTGTGGTGACGGGGGGGGGGCGGGGCCTCCACCTGTGACAGCCAGGCTTGAGGGTGGACGGCGTGCCTCTCCCAGGAGCCTTCCCCATG
TCCTTGCCTTGCTGAGAATTGCCCTCCCATGCCGCTGAGGTGTTAGGTGGTTTAGGGCCAAAAGGGGAAAACCACTTGAGTCTTGTGGTG
TGTGGTGGGCAGACACCACAGGGTGGCATCACCTGGTGGCATTTCCAGAACCTCAGCCCCGATTCCAGCACCCACCACCGCCTGACCCTG
TGTAACCTGCTGTCCCGGGTCCCAGAGTGCACTCTGCCCCGCTGCTCTGCTGCCTGTCCTGGGAAAGTATCTTTGCCCCACTAGGAAATG
TAAACAGGAGGGCTTGGGGAGCGTGGGCACTTTTCTCATGAGCAGCTACTGCGGCGTTGGCAGGACTCGCTGCTGCTGCTGCTGCTTGTG
TAGGTCGGGGAGCCAGAGATCCCCGAGGACGCGCGCCGGACAGTCGGCACTGACCGGCCCACCTGGTAGCAGAGGACACCCCCAGCCCCC
CAAGCATTGAAGACATAGTGTATTTCCTCGTATCCTTTCTCCCTTGGGTGTAGTTGGGGTGGGGAAGCAGGGAAGGCTGGTGCGATCTCC
ATTCCTTGGGCTCCACGTCCGAGTTCATGGTGCGCCGCTGTGCTGGGAGCTGCAGTGGTAATGTGTGGGACACCTTGACCAAAGGGGAGC
TTTGTCTCGTGTGTTTTGAAAAAGGCTTAATGAAGAGAATGTTGTTCATTCTTAGTAGTATAGTTTGCAATTCTTAATGGCAAATAATAA

>In-frame_ENST00000336665_ENST00000405546_TCGA-DX-A3U7-01A_AGAP1_chr2_236403493_+_ATG4B_chr2_242590425_length(amino acids)=484AA_start in transcript=421_stop in transcript=1875
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCML
RCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAV
HIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVI
GGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGAL

--------------------------------------------------------------
>In-frame_ENST00000304032_ENST00000405546_TCGA-DX-A3U7-01A_AGAP1_chr2_236403493_+_ATG4B_chr2_242590425_length(transcript)=3525nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGACACTCTCCGGTTTGCTGAGTTTGAAGATTTTCCTGAGACCTCAGAGCCCGT
TTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAGGACGAGATCTTGTCTGATGTGGCATCTAGACTTTGGTTTACATACAGGAA
AAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGACACAGGCTGGGGCTGCATGCTGCGGTGTGGACAGATGATCTTTGCCCAAGC
CCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACACAAAGGAAGAGGCAGCCAGACAGCTACTTCAGCGTCCTCAACGCATTCAT
CGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCGCAAATGGGAGTTGGCGAAGGCAAGTCCATAGGCCAGTGGTACGGGCCCAA
CACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGATACGTGGAGCTCCTTGGCGGTCCACATTGCAATGGACAACACTGTTGTGAT
GGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGTGCAGGCGCCACTGCGTTTCCTGCAGATTCCGACCGGCACTGCAACGGATT
CCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGACCCCTGGTACTTCTCATTCCCCTGCGCCTGGGGCTCACGGACATCAA
CGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATGCCCCAGTCCCTGGGCGTCATCGGAGGGAAGCCCAACAGCGCCCACTACTT
CATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCCCACACCACGCAGCCAGCCGTGGAGCCCACTGATGGCTGCTTCATCCCGGA
CGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGCATCGCGGAGCTTGACCCGTCCATCGCTGTGGGGTTTTTCTGTAAGACTGA
AGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTGTCTCTGCTTGGAGGTGCCCTGCCCATGTTTGAGCTGGTGGAGCTGCAGCC
TTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTAGGTGAGAGCTGCCAAGTCCAGATTCTTCTGATGTAGAGCGACTGGAAAGA
TTCTTCGACTCAGAAGATGAAGACTTTGAAATCCTGTCCCTTTGAAAATCCTGGGGTCGGGGGTGGCACCTGTGAGAGCCTGGGGCTCCT
GGTGCCGCTGCGTTTCATCCATCCCGCCCGCTCGCCTGCCGAGGGCTGCGCCCCGTGCTGCCTCCCCCCAGAGGGCCACCCGCTGTGCTC
GTGGACTGAGGCTGCGCTGCCCGGGAGGCCTTACTGCTTGGTGTCAGACTGCCCAGCTCAGAGTGCCCGTCAGGGCCTGTGCATCCGCAC
GCGGAGCCGTCTGTTAGGAGCTTCCAGAGTGTTCTCTCGACACTGCCAGCCCCGTGTTAGCACCTGGGCCTCAGTCCCACTTGCTCCCAG
GCGCCGGTTCTGTGGTTGGTTTGGAATTAAAGTCCTGTTTGAAGTTGTCAGACACAGACATGAATTTCTGGGCGCTCCCTGAGTCAGAGT
CTCAGAAGACCTGTGCAGGCTGGCGTGAGAGGAGCGGCAGCCACACTGCGGCCCCACGCCCAAGGACTGGGCTGCTCTCGAGGGGGGCGC
GCCCACCGCTGTGTCCTCTCTGCCCAGCCTGGCTTACCAAGGGCTACCTCAGTGGGAGATGAGGTTGGAGGAACGAAGGCGAGGTTCCTC
CTTGCTTTGGGGAGAAAAGTATTCAGGAAGTGGGTGTGTGGGAAACCTGAAGATGGCGTGCACAGGACACAGCGTGGGCGGCCTGGGCAG
AAGGGCGGCTGGCTGTCCTGGAGCTGCTGCTGGAGCCTGCCCTCAGAGTGTCCCTTTCCAGTGCTGTGGCATTCTGTGGCAGCTTCCCCA
GGTGTGGTGACGGGGGGGGGGCGGGGCCTCCACCTGTGACAGCCAGGCTTGAGGGTGGACGGCGTGCCTCTCCCAGGAGCCTTCCCCATG
TCCTTGCCTTGCTGAGAATTGCCCTCCCATGCCGCTGAGGTGTTAGGTGGTTTAGGGCCAAAAGGGGAAAACCACTTGAGTCTTGTGGTG
TGTGGTGGGCAGACACCACAGGGTGGCATCACCTGGTGGCATTTCCAGAACCTCAGCCCCGATTCCAGCACCCACCACCGCCTGACCCTG
TGTAACCTGCTGTCCCGGGTCCCAGAGTGCACTCTGCCCCGCTGCTCTGCTGCCTGTCCTGGGAAAGTATCTTTGCCCCACTAGGAAATG
TAAACAGGAGGGCTTGGGGAGCGTGGGCACTTTTCTCATGAGCAGCTACTGCGGCGTTGGCAGGACTCGCTGCTGCTGCTGCTGCTTGTG
TAGGTCGGGGAGCCAGAGATCCCCGAGGACGCGCGCCGGACAGTCGGCACTGACCGGCCCACCTGGTAGCAGAGGACACCCCCAGCCCCC
CAAGCATTGAAGACATAGTGTATTTCCTCGTATCCTTTCTCCCTTGGGTGTAGTTGGGGTGGGGAAGCAGGGAAGGCTGGTGCGATCTCC
ATTCCTTGGGCTCCACGTCCGAGTTCATGGTGCGCCGCTGTGCTGGGAGCTGCAGTGGTAATGTGTGGGACACCTTGACCAAAGGGGAGC
TTTGTCTCGTGTGTTTTGAAAAAGGCTTAATGAAGAGAATGTTGTTCATTCTTAGTAGTATAGTTTGCAATTCTTAATGGCAAATAATAA

>In-frame_ENST00000304032_ENST00000405546_TCGA-DX-A3U7-01A_AGAP1_chr2_236403493_+_ATG4B_chr2_242590425_length(amino acids)=484AA_start in transcript=421_stop in transcript=1875
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCML
RCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAV
HIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVI
GGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGAL

--------------------------------------------------------------
>In-frame_ENST00000409457_ENST00000405546_TCGA-DX-A3U7-01A_AGAP1_chr2_236403493_+_ATG4B_chr2_242590425_length(transcript)=3543nt_BP=761nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC
CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC
CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC
TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC
TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC
CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC
TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT
GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGACACTCTCCGGTTTGCTGAGTTTGAAGATTTTCC
TGAGACCTCAGAGCCCGTTTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAGGACGAGATCTTGTCTGATGTGGCATCTAGACT
TTGGTTTACATACAGGAAAAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGACACAGGCTGGGGCTGCATGCTGCGGTGTGGACA
GATGATCTTTGCCCAAGCCCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACACAAAGGAAGAGGCAGCCAGACAGCTACTTCAG
CGTCCTCAACGCATTCATCGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCGCAAATGGGAGTTGGCGAAGGCAAGTCCATAGG
CCAGTGGTACGGGCCCAACACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGATACGTGGAGCTCCTTGGCGGTCCACATTGCAAT
GGACAACACTGTTGTGATGGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGTGCAGGCGCCACTGCGTTTCCTGCAGATTCCGA
CCGGCACTGCAACGGATTCCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGACCCCTGGTACTTCTCATTCCCCTGCGCCT
GGGGCTCACGGACATCAACGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATGCCCCAGTCCCTGGGCGTCATCGGAGGGAAGCC
CAACAGCGCCCACTACTTCATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCCCACACCACGCAGCCAGCCGTGGAGCCCACTGA
TGGCTGCTTCATCCCGGACGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGCATCGCGGAGCTTGACCCGTCCATCGCTGTGGG
GTTTTTCTGTAAGACTGAAGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTGTCTCTGCTTGGAGGTGCCCTGCCCATGTTTGA
GCTGGTGGAGCTGCAGCCTTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTAGGTGAGAGCTGCCAAGTCCAGATTCTTCTGAT
GTAGAGCGACTGGAAAGATTCTTCGACTCAGAAGATGAAGACTTTGAAATCCTGTCCCTTTGAAAATCCTGGGGTCGGGGGTGGCACCTG
TGAGAGCCTGGGGCTCCTGGTGCCGCTGCGTTTCATCCATCCCGCCCGCTCGCCTGCCGAGGGCTGCGCCCCGTGCTGCCTCCCCCCAGA
GGGCCACCCGCTGTGCTCGTGGACTGAGGCTGCGCTGCCCGGGAGGCCTTACTGCTTGGTGTCAGACTGCCCAGCTCAGAGTGCCCGTCA
GGGCCTGTGCATCCGCACGCGGAGCCGTCTGTTAGGAGCTTCCAGAGTGTTCTCTCGACACTGCCAGCCCCGTGTTAGCACCTGGGCCTC
AGTCCCACTTGCTCCCAGGCGCCGGTTCTGTGGTTGGTTTGGAATTAAAGTCCTGTTTGAAGTTGTCAGACACAGACATGAATTTCTGGG
CGCTCCCTGAGTCAGAGTCTCAGAAGACCTGTGCAGGCTGGCGTGAGAGGAGCGGCAGCCACACTGCGGCCCCACGCCCAAGGACTGGGC
TGCTCTCGAGGGGGGCGCGCCCACCGCTGTGTCCTCTCTGCCCAGCCTGGCTTACCAAGGGCTACCTCAGTGGGAGATGAGGTTGGAGGA
ACGAAGGCGAGGTTCCTCCTTGCTTTGGGGAGAAAAGTATTCAGGAAGTGGGTGTGTGGGAAACCTGAAGATGGCGTGCACAGGACACAG
CGTGGGCGGCCTGGGCAGAAGGGCGGCTGGCTGTCCTGGAGCTGCTGCTGGAGCCTGCCCTCAGAGTGTCCCTTTCCAGTGCTGTGGCAT
TCTGTGGCAGCTTCCCCAGGTGTGGTGACGGGGGGGGGGCGGGGCCTCCACCTGTGACAGCCAGGCTTGAGGGTGGACGGCGTGCCTCTC
CCAGGAGCCTTCCCCATGTCCTTGCCTTGCTGAGAATTGCCCTCCCATGCCGCTGAGGTGTTAGGTGGTTTAGGGCCAAAAGGGGAAAAC
CACTTGAGTCTTGTGGTGTGTGGTGGGCAGACACCACAGGGTGGCATCACCTGGTGGCATTTCCAGAACCTCAGCCCCGATTCCAGCACC
CACCACCGCCTGACCCTGTGTAACCTGCTGTCCCGGGTCCCAGAGTGCACTCTGCCCCGCTGCTCTGCTGCCTGTCCTGGGAAAGTATCT
TTGCCCCACTAGGAAATGTAAACAGGAGGGCTTGGGGAGCGTGGGCACTTTTCTCATGAGCAGCTACTGCGGCGTTGGCAGGACTCGCTG
CTGCTGCTGCTGCTTGTGTAGGTCGGGGAGCCAGAGATCCCCGAGGACGCGCGCCGGACAGTCGGCACTGACCGGCCCACCTGGTAGCAG
AGGACACCCCCAGCCCCCCAAGCATTGAAGACATAGTGTATTTCCTCGTATCCTTTCTCCCTTGGGTGTAGTTGGGGTGGGGAAGCAGGG
AAGGCTGGTGCGATCTCCATTCCTTGGGCTCCACGTCCGAGTTCATGGTGCGCCGCTGTGCTGGGAGCTGCAGTGGTAATGTGTGGGACA
CCTTGACCAAAGGGGAGCTTTGTCTCGTGTGTTTTGAAAAAGGCTTAATGAAGAGAATGTTGTTCATTCTTAGTAGTATAGTTTGCAATT

>In-frame_ENST00000409457_ENST00000405546_TCGA-DX-A3U7-01A_AGAP1_chr2_236403493_+_ATG4B_chr2_242590425_length(amino acids)=484AA_start in transcript=439_stop in transcript=1893
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCML
RCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAV
HIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVI
GGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGAL

--------------------------------------------------------------
>In-frame_ENST00000336665_ENST00000405546_TCGA-DX-A3U7_AGAP1_chr2_236403493_+_ATG4B_chr2_242590424_length(transcript)=3525nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGACACTCTCCGGTTTGCTGAGTTTGAAGATTTTCCTGAGACCTCAGAGCCCGT
TTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAGGACGAGATCTTGTCTGATGTGGCATCTAGACTTTGGTTTACATACAGGAA
AAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGACACAGGCTGGGGCTGCATGCTGCGGTGTGGACAGATGATCTTTGCCCAAGC
CCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACACAAAGGAAGAGGCAGCCAGACAGCTACTTCAGCGTCCTCAACGCATTCAT
CGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCGCAAATGGGAGTTGGCGAAGGCAAGTCCATAGGCCAGTGGTACGGGCCCAA
CACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGATACGTGGAGCTCCTTGGCGGTCCACATTGCAATGGACAACACTGTTGTGAT
GGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGTGCAGGCGCCACTGCGTTTCCTGCAGATTCCGACCGGCACTGCAACGGATT
CCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGACCCCTGGTACTTCTCATTCCCCTGCGCCTGGGGCTCACGGACATCAA
CGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATGCCCCAGTCCCTGGGCGTCATCGGAGGGAAGCCCAACAGCGCCCACTACTT
CATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCCCACACCACGCAGCCAGCCGTGGAGCCCACTGATGGCTGCTTCATCCCGGA
CGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGCATCGCGGAGCTTGACCCGTCCATCGCTGTGGGGTTTTTCTGTAAGACTGA
AGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTGTCTCTGCTTGGAGGTGCCCTGCCCATGTTTGAGCTGGTGGAGCTGCAGCC
TTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTAGGTGAGAGCTGCCAAGTCCAGATTCTTCTGATGTAGAGCGACTGGAAAGA
TTCTTCGACTCAGAAGATGAAGACTTTGAAATCCTGTCCCTTTGAAAATCCTGGGGTCGGGGGTGGCACCTGTGAGAGCCTGGGGCTCCT
GGTGCCGCTGCGTTTCATCCATCCCGCCCGCTCGCCTGCCGAGGGCTGCGCCCCGTGCTGCCTCCCCCCAGAGGGCCACCCGCTGTGCTC
GTGGACTGAGGCTGCGCTGCCCGGGAGGCCTTACTGCTTGGTGTCAGACTGCCCAGCTCAGAGTGCCCGTCAGGGCCTGTGCATCCGCAC
GCGGAGCCGTCTGTTAGGAGCTTCCAGAGTGTTCTCTCGACACTGCCAGCCCCGTGTTAGCACCTGGGCCTCAGTCCCACTTGCTCCCAG
GCGCCGGTTCTGTGGTTGGTTTGGAATTAAAGTCCTGTTTGAAGTTGTCAGACACAGACATGAATTTCTGGGCGCTCCCTGAGTCAGAGT
CTCAGAAGACCTGTGCAGGCTGGCGTGAGAGGAGCGGCAGCCACACTGCGGCCCCACGCCCAAGGACTGGGCTGCTCTCGAGGGGGGCGC
GCCCACCGCTGTGTCCTCTCTGCCCAGCCTGGCTTACCAAGGGCTACCTCAGTGGGAGATGAGGTTGGAGGAACGAAGGCGAGGTTCCTC
CTTGCTTTGGGGAGAAAAGTATTCAGGAAGTGGGTGTGTGGGAAACCTGAAGATGGCGTGCACAGGACACAGCGTGGGCGGCCTGGGCAG
AAGGGCGGCTGGCTGTCCTGGAGCTGCTGCTGGAGCCTGCCCTCAGAGTGTCCCTTTCCAGTGCTGTGGCATTCTGTGGCAGCTTCCCCA
GGTGTGGTGACGGGGGGGGGGCGGGGCCTCCACCTGTGACAGCCAGGCTTGAGGGTGGACGGCGTGCCTCTCCCAGGAGCCTTCCCCATG
TCCTTGCCTTGCTGAGAATTGCCCTCCCATGCCGCTGAGGTGTTAGGTGGTTTAGGGCCAAAAGGGGAAAACCACTTGAGTCTTGTGGTG
TGTGGTGGGCAGACACCACAGGGTGGCATCACCTGGTGGCATTTCCAGAACCTCAGCCCCGATTCCAGCACCCACCACCGCCTGACCCTG
TGTAACCTGCTGTCCCGGGTCCCAGAGTGCACTCTGCCCCGCTGCTCTGCTGCCTGTCCTGGGAAAGTATCTTTGCCCCACTAGGAAATG
TAAACAGGAGGGCTTGGGGAGCGTGGGCACTTTTCTCATGAGCAGCTACTGCGGCGTTGGCAGGACTCGCTGCTGCTGCTGCTGCTTGTG
TAGGTCGGGGAGCCAGAGATCCCCGAGGACGCGCGCCGGACAGTCGGCACTGACCGGCCCACCTGGTAGCAGAGGACACCCCCAGCCCCC
CAAGCATTGAAGACATAGTGTATTTCCTCGTATCCTTTCTCCCTTGGGTGTAGTTGGGGTGGGGAAGCAGGGAAGGCTGGTGCGATCTCC
ATTCCTTGGGCTCCACGTCCGAGTTCATGGTGCGCCGCTGTGCTGGGAGCTGCAGTGGTAATGTGTGGGACACCTTGACCAAAGGGGAGC
TTTGTCTCGTGTGTTTTGAAAAAGGCTTAATGAAGAGAATGTTGTTCATTCTTAGTAGTATAGTTTGCAATTCTTAATGGCAAATAATAA

>In-frame_ENST00000336665_ENST00000405546_TCGA-DX-A3U7_AGAP1_chr2_236403493_+_ATG4B_chr2_242590424_length(amino acids)=484AA_start in transcript=421_stop in transcript=1875
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCML
RCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAV
HIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVI
GGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGAL

--------------------------------------------------------------
>In-frame_ENST00000304032_ENST00000405546_TCGA-DX-A3U7_AGAP1_chr2_236403493_+_ATG4B_chr2_242590424_length(transcript)=3525nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGACACTCTCCGGTTTGCTGAGTTTGAAGATTTTCCTGAGACCTCAGAGCCCGT
TTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAGGACGAGATCTTGTCTGATGTGGCATCTAGACTTTGGTTTACATACAGGAA
AAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGACACAGGCTGGGGCTGCATGCTGCGGTGTGGACAGATGATCTTTGCCCAAGC
CCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACACAAAGGAAGAGGCAGCCAGACAGCTACTTCAGCGTCCTCAACGCATTCAT
CGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCGCAAATGGGAGTTGGCGAAGGCAAGTCCATAGGCCAGTGGTACGGGCCCAA
CACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGATACGTGGAGCTCCTTGGCGGTCCACATTGCAATGGACAACACTGTTGTGAT
GGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGTGCAGGCGCCACTGCGTTTCCTGCAGATTCCGACCGGCACTGCAACGGATT
CCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGACCCCTGGTACTTCTCATTCCCCTGCGCCTGGGGCTCACGGACATCAA
CGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATGCCCCAGTCCCTGGGCGTCATCGGAGGGAAGCCCAACAGCGCCCACTACTT
CATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCCCACACCACGCAGCCAGCCGTGGAGCCCACTGATGGCTGCTTCATCCCGGA
CGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGCATCGCGGAGCTTGACCCGTCCATCGCTGTGGGGTTTTTCTGTAAGACTGA
AGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTGTCTCTGCTTGGAGGTGCCCTGCCCATGTTTGAGCTGGTGGAGCTGCAGCC
TTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTAGGTGAGAGCTGCCAAGTCCAGATTCTTCTGATGTAGAGCGACTGGAAAGA
TTCTTCGACTCAGAAGATGAAGACTTTGAAATCCTGTCCCTTTGAAAATCCTGGGGTCGGGGGTGGCACCTGTGAGAGCCTGGGGCTCCT
GGTGCCGCTGCGTTTCATCCATCCCGCCCGCTCGCCTGCCGAGGGCTGCGCCCCGTGCTGCCTCCCCCCAGAGGGCCACCCGCTGTGCTC
GTGGACTGAGGCTGCGCTGCCCGGGAGGCCTTACTGCTTGGTGTCAGACTGCCCAGCTCAGAGTGCCCGTCAGGGCCTGTGCATCCGCAC
GCGGAGCCGTCTGTTAGGAGCTTCCAGAGTGTTCTCTCGACACTGCCAGCCCCGTGTTAGCACCTGGGCCTCAGTCCCACTTGCTCCCAG
GCGCCGGTTCTGTGGTTGGTTTGGAATTAAAGTCCTGTTTGAAGTTGTCAGACACAGACATGAATTTCTGGGCGCTCCCTGAGTCAGAGT
CTCAGAAGACCTGTGCAGGCTGGCGTGAGAGGAGCGGCAGCCACACTGCGGCCCCACGCCCAAGGACTGGGCTGCTCTCGAGGGGGGCGC
GCCCACCGCTGTGTCCTCTCTGCCCAGCCTGGCTTACCAAGGGCTACCTCAGTGGGAGATGAGGTTGGAGGAACGAAGGCGAGGTTCCTC
CTTGCTTTGGGGAGAAAAGTATTCAGGAAGTGGGTGTGTGGGAAACCTGAAGATGGCGTGCACAGGACACAGCGTGGGCGGCCTGGGCAG
AAGGGCGGCTGGCTGTCCTGGAGCTGCTGCTGGAGCCTGCCCTCAGAGTGTCCCTTTCCAGTGCTGTGGCATTCTGTGGCAGCTTCCCCA
GGTGTGGTGACGGGGGGGGGGCGGGGCCTCCACCTGTGACAGCCAGGCTTGAGGGTGGACGGCGTGCCTCTCCCAGGAGCCTTCCCCATG
TCCTTGCCTTGCTGAGAATTGCCCTCCCATGCCGCTGAGGTGTTAGGTGGTTTAGGGCCAAAAGGGGAAAACCACTTGAGTCTTGTGGTG
TGTGGTGGGCAGACACCACAGGGTGGCATCACCTGGTGGCATTTCCAGAACCTCAGCCCCGATTCCAGCACCCACCACCGCCTGACCCTG
TGTAACCTGCTGTCCCGGGTCCCAGAGTGCACTCTGCCCCGCTGCTCTGCTGCCTGTCCTGGGAAAGTATCTTTGCCCCACTAGGAAATG
TAAACAGGAGGGCTTGGGGAGCGTGGGCACTTTTCTCATGAGCAGCTACTGCGGCGTTGGCAGGACTCGCTGCTGCTGCTGCTGCTTGTG
TAGGTCGGGGAGCCAGAGATCCCCGAGGACGCGCGCCGGACAGTCGGCACTGACCGGCCCACCTGGTAGCAGAGGACACCCCCAGCCCCC
CAAGCATTGAAGACATAGTGTATTTCCTCGTATCCTTTCTCCCTTGGGTGTAGTTGGGGTGGGGAAGCAGGGAAGGCTGGTGCGATCTCC
ATTCCTTGGGCTCCACGTCCGAGTTCATGGTGCGCCGCTGTGCTGGGAGCTGCAGTGGTAATGTGTGGGACACCTTGACCAAAGGGGAGC
TTTGTCTCGTGTGTTTTGAAAAAGGCTTAATGAAGAGAATGTTGTTCATTCTTAGTAGTATAGTTTGCAATTCTTAATGGCAAATAATAA

>In-frame_ENST00000304032_ENST00000405546_TCGA-DX-A3U7_AGAP1_chr2_236403493_+_ATG4B_chr2_242590424_length(amino acids)=484AA_start in transcript=421_stop in transcript=1875
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCML
RCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAV
HIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVI
GGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGAL

--------------------------------------------------------------
>In-frame_ENST00000409457_ENST00000405546_TCGA-DX-A3U7_AGAP1_chr2_236403493_+_ATG4B_chr2_242590424_length(transcript)=3543nt_BP=761nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC
CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC
CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC
TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC
TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC
CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC
TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT
GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGACACTCTCCGGTTTGCTGAGTTTGAAGATTTTCC
TGAGACCTCAGAGCCCGTTTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAGGACGAGATCTTGTCTGATGTGGCATCTAGACT
TTGGTTTACATACAGGAAAAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGACACAGGCTGGGGCTGCATGCTGCGGTGTGGACA
GATGATCTTTGCCCAAGCCCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACACAAAGGAAGAGGCAGCCAGACAGCTACTTCAG
CGTCCTCAACGCATTCATCGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCGCAAATGGGAGTTGGCGAAGGCAAGTCCATAGG
CCAGTGGTACGGGCCCAACACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGATACGTGGAGCTCCTTGGCGGTCCACATTGCAAT
GGACAACACTGTTGTGATGGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGTGCAGGCGCCACTGCGTTTCCTGCAGATTCCGA
CCGGCACTGCAACGGATTCCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGACCCCTGGTACTTCTCATTCCCCTGCGCCT
GGGGCTCACGGACATCAACGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATGCCCCAGTCCCTGGGCGTCATCGGAGGGAAGCC
CAACAGCGCCCACTACTTCATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCCCACACCACGCAGCCAGCCGTGGAGCCCACTGA
TGGCTGCTTCATCCCGGACGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGCATCGCGGAGCTTGACCCGTCCATCGCTGTGGG
GTTTTTCTGTAAGACTGAAGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTGTCTCTGCTTGGAGGTGCCCTGCCCATGTTTGA
GCTGGTGGAGCTGCAGCCTTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTAGGTGAGAGCTGCCAAGTCCAGATTCTTCTGAT
GTAGAGCGACTGGAAAGATTCTTCGACTCAGAAGATGAAGACTTTGAAATCCTGTCCCTTTGAAAATCCTGGGGTCGGGGGTGGCACCTG
TGAGAGCCTGGGGCTCCTGGTGCCGCTGCGTTTCATCCATCCCGCCCGCTCGCCTGCCGAGGGCTGCGCCCCGTGCTGCCTCCCCCCAGA
GGGCCACCCGCTGTGCTCGTGGACTGAGGCTGCGCTGCCCGGGAGGCCTTACTGCTTGGTGTCAGACTGCCCAGCTCAGAGTGCCCGTCA
GGGCCTGTGCATCCGCACGCGGAGCCGTCTGTTAGGAGCTTCCAGAGTGTTCTCTCGACACTGCCAGCCCCGTGTTAGCACCTGGGCCTC
AGTCCCACTTGCTCCCAGGCGCCGGTTCTGTGGTTGGTTTGGAATTAAAGTCCTGTTTGAAGTTGTCAGACACAGACATGAATTTCTGGG
CGCTCCCTGAGTCAGAGTCTCAGAAGACCTGTGCAGGCTGGCGTGAGAGGAGCGGCAGCCACACTGCGGCCCCACGCCCAAGGACTGGGC
TGCTCTCGAGGGGGGCGCGCCCACCGCTGTGTCCTCTCTGCCCAGCCTGGCTTACCAAGGGCTACCTCAGTGGGAGATGAGGTTGGAGGA
ACGAAGGCGAGGTTCCTCCTTGCTTTGGGGAGAAAAGTATTCAGGAAGTGGGTGTGTGGGAAACCTGAAGATGGCGTGCACAGGACACAG
CGTGGGCGGCCTGGGCAGAAGGGCGGCTGGCTGTCCTGGAGCTGCTGCTGGAGCCTGCCCTCAGAGTGTCCCTTTCCAGTGCTGTGGCAT
TCTGTGGCAGCTTCCCCAGGTGTGGTGACGGGGGGGGGGCGGGGCCTCCACCTGTGACAGCCAGGCTTGAGGGTGGACGGCGTGCCTCTC
CCAGGAGCCTTCCCCATGTCCTTGCCTTGCTGAGAATTGCCCTCCCATGCCGCTGAGGTGTTAGGTGGTTTAGGGCCAAAAGGGGAAAAC
CACTTGAGTCTTGTGGTGTGTGGTGGGCAGACACCACAGGGTGGCATCACCTGGTGGCATTTCCAGAACCTCAGCCCCGATTCCAGCACC
CACCACCGCCTGACCCTGTGTAACCTGCTGTCCCGGGTCCCAGAGTGCACTCTGCCCCGCTGCTCTGCTGCCTGTCCTGGGAAAGTATCT
TTGCCCCACTAGGAAATGTAAACAGGAGGGCTTGGGGAGCGTGGGCACTTTTCTCATGAGCAGCTACTGCGGCGTTGGCAGGACTCGCTG
CTGCTGCTGCTGCTTGTGTAGGTCGGGGAGCCAGAGATCCCCGAGGACGCGCGCCGGACAGTCGGCACTGACCGGCCCACCTGGTAGCAG
AGGACACCCCCAGCCCCCCAAGCATTGAAGACATAGTGTATTTCCTCGTATCCTTTCTCCCTTGGGTGTAGTTGGGGTGGGGAAGCAGGG
AAGGCTGGTGCGATCTCCATTCCTTGGGCTCCACGTCCGAGTTCATGGTGCGCCGCTGTGCTGGGAGCTGCAGTGGTAATGTGTGGGACA
CCTTGACCAAAGGGGAGCTTTGTCTCGTGTGTTTTGAAAAAGGCTTAATGAAGAGAATGTTGTTCATTCTTAGTAGTATAGTTTGCAATT

>In-frame_ENST00000409457_ENST00000405546_TCGA-DX-A3U7_AGAP1_chr2_236403493_+_ATG4B_chr2_242590424_length(amino acids)=484AA_start in transcript=439_stop in transcript=1893
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCML
RCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAV
HIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVI
GGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGAL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AGAP1-ATG4B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AGAP1-ATG4B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AGAP1-ATG4B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAGAP1C0004352Autistic Disorder1CTD_human