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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FAM76A-WDTC1 (FusionGDB2 ID:29117)

Fusion Gene Summary for FAM76A-WDTC1

check button Fusion gene summary
Fusion gene informationFusion gene name: FAM76A-WDTC1
Fusion gene ID: 29117
HgeneTgene
Gene symbol

FAM76A

WDTC1

Gene ID

199870

23038

Gene namefamily with sequence similarity 76 member AWD and tetratricopeptide repeats 1
Synonyms-ADP|DCAF9
Cytomap

1p35.3

1p36.11

Type of geneprotein-codingprotein-coding
Descriptionprotein FAM76AWD and tetratricopeptide repeats protein 1DDB1 and CUL4 associated factor 9adipose homolog
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000373954, ENST00000419687, 
ENST00000530324, ENST00000234549, 
ENST00000373949, ENST00000010299, 
ENST00000319394, ENST00000361771, 
Fusion gene scores* DoF score5 X 4 X 4=8011 X 11 X 10=1210
# samples 517
** MAII scorelog2(5/80*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1210*10)=-2.83140039602426
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FAM76A [Title/Abstract] AND WDTC1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFAM76A(28075665)-WDTC1(27631492), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across FAM76A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across WDTC1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-44-6778-01AFAM76Achr1

28075665

-WDTC1chr1

27631492

+


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Fusion Gene ORF analysis for FAM76A-WDTC1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000373954ENST00000319394FAM76Achr1

28075665

-WDTC1chr1

27631492

+
In-frameENST00000373954ENST00000361771FAM76Achr1

28075665

-WDTC1chr1

27631492

+
intron-3CDSENST00000419687ENST00000319394FAM76Achr1

28075665

-WDTC1chr1

27631492

+
intron-3CDSENST00000419687ENST00000361771FAM76Achr1

28075665

-WDTC1chr1

27631492

+
In-frameENST00000530324ENST00000319394FAM76Achr1

28075665

-WDTC1chr1

27631492

+
In-frameENST00000530324ENST00000361771FAM76Achr1

28075665

-WDTC1chr1

27631492

+
intron-3CDSENST00000234549ENST00000319394FAM76Achr1

28075665

-WDTC1chr1

27631492

+
intron-3CDSENST00000234549ENST00000361771FAM76Achr1

28075665

-WDTC1chr1

27631492

+
intron-3CDSENST00000373949ENST00000319394FAM76Achr1

28075665

-WDTC1chr1

27631492

+
intron-3CDSENST00000373949ENST00000361771FAM76Achr1

28075665

-WDTC1chr1

27631492

+
In-frameENST00000010299ENST00000319394FAM76Achr1

28075665

-WDTC1chr1

27631492

+
In-frameENST00000010299ENST00000361771FAM76Achr1

28075665

-WDTC1chr1

27631492

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000373954FAM76Achr128075665-ENST00000319394WDTC1chr127631492+33287011021091329
ENST00000373954FAM76Achr128075665-ENST00000361771WDTC1chr127631492+29537011021091329
ENST00000530324FAM76Achr128075665-ENST00000319394WDTC1chr127631492+3279652531042329
ENST00000530324FAM76Achr128075665-ENST00000361771WDTC1chr127631492+2904652531042329
ENST00000010299FAM76Achr128075665-ENST00000319394WDTC1chr127631492+3352725241115363
ENST00000010299FAM76Achr128075665-ENST00000361771WDTC1chr127631492+2977725241115363

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000373954ENST00000319394FAM76Achr128075665-WDTC1chr127631492+0.0042945830.9957054
ENST00000373954ENST00000361771FAM76Achr128075665-WDTC1chr127631492+0.0061150650.993885
ENST00000530324ENST00000319394FAM76Achr128075665-WDTC1chr127631492+0.0040125540.9959875
ENST00000530324ENST00000361771FAM76Achr128075665-WDTC1chr127631492+0.0056090760.9943909
ENST00000010299ENST00000319394FAM76Achr128075665-WDTC1chr127631492+0.003408450.99659157
ENST00000010299ENST00000361771FAM76Achr128075665-WDTC1chr127631492+0.0052907290.99470925

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Fusion Genomic Features for FAM76A-WDTC1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FAM76A-WDTC1


check button Go to

FGviewer for the breakpoints of chr1:28075665-chr1:27631492

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAM76Achr1:28075665chr1:27631492ENST00000010299-710147_150233.66666666666666342.0Compositional biasNote=Poly-Ser
HgeneFAM76Achr1:28075665chr1:27631492ENST00000373954-69147_150199.66666666666666308.0Compositional biasNote=Poly-Ser
TgeneWDTC1chr1:28075665chr1:27631492ENST000003193941316578_617547.6666666666666678.0RepeatNote=WD 7
TgeneWDTC1chr1:28075665chr1:27631492ENST000003617711316578_617546.6666666666666677.0RepeatNote=WD 7

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAM76Achr1:28075665chr1:27631492ENST00000010299-710217_299233.66666666666666342.0Coiled coilOntology_term=ECO:0000255
HgeneFAM76Achr1:28075665chr1:27631492ENST00000234549-19217_2990313.0Coiled coilOntology_term=ECO:0000255
HgeneFAM76Achr1:28075665chr1:27631492ENST00000373949-18217_2990279.0Coiled coilOntology_term=ECO:0000255
HgeneFAM76Achr1:28075665chr1:27631492ENST00000373954-69217_299199.66666666666666308.0Coiled coilOntology_term=ECO:0000255
HgeneFAM76Achr1:28075665chr1:27631492ENST00000419687-17217_2990228.0Coiled coilOntology_term=ECO:0000255
HgeneFAM76Achr1:28075665chr1:27631492ENST00000234549-19147_1500313.0Compositional biasNote=Poly-Ser
HgeneFAM76Achr1:28075665chr1:27631492ENST00000373949-18147_1500279.0Compositional biasNote=Poly-Ser
HgeneFAM76Achr1:28075665chr1:27631492ENST00000419687-17147_1500228.0Compositional biasNote=Poly-Ser
TgeneWDTC1chr1:28075665chr1:27631492ENST000003193941316132_172547.6666666666666678.0RepeatNote=WD 3
TgeneWDTC1chr1:28075665chr1:27631492ENST000003193941316182_222547.6666666666666678.0RepeatNote=WD 4
TgeneWDTC1chr1:28075665chr1:27631492ENST000003193941316265_305547.6666666666666678.0RepeatNote=WD 5
TgeneWDTC1chr1:28075665chr1:27631492ENST000003193941316362_395547.6666666666666678.0RepeatNote=TPR 1
TgeneWDTC1chr1:28075665chr1:27631492ENST000003193941316397_432547.6666666666666678.0RepeatNote=TPR 2
TgeneWDTC1chr1:28075665chr1:27631492ENST00000319394131645_84547.6666666666666678.0RepeatNote=WD 1
TgeneWDTC1chr1:28075665chr1:27631492ENST000003193941316535_575547.6666666666666678.0RepeatNote=WD 6
TgeneWDTC1chr1:28075665chr1:27631492ENST00000319394131688_129547.6666666666666678.0RepeatNote=WD 2
TgeneWDTC1chr1:28075665chr1:27631492ENST000003617711316132_172546.6666666666666677.0RepeatNote=WD 3
TgeneWDTC1chr1:28075665chr1:27631492ENST000003617711316182_222546.6666666666666677.0RepeatNote=WD 4
TgeneWDTC1chr1:28075665chr1:27631492ENST000003617711316265_305546.6666666666666677.0RepeatNote=WD 5
TgeneWDTC1chr1:28075665chr1:27631492ENST000003617711316362_395546.6666666666666677.0RepeatNote=TPR 1
TgeneWDTC1chr1:28075665chr1:27631492ENST000003617711316397_432546.6666666666666677.0RepeatNote=TPR 2
TgeneWDTC1chr1:28075665chr1:27631492ENST00000361771131645_84546.6666666666666677.0RepeatNote=WD 1
TgeneWDTC1chr1:28075665chr1:27631492ENST000003617711316535_575546.6666666666666677.0RepeatNote=WD 6
TgeneWDTC1chr1:28075665chr1:27631492ENST00000361771131688_129546.6666666666666677.0RepeatNote=WD 2


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Fusion Gene Sequence for FAM76A-WDTC1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000373954_ENST00000319394_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(transcript)=3328nt_BP=701nt
GCCGCAGCCAGCAGCCTGCAGCCGCCGCCGGGTTGTGCCTCAGACTGTCAGATAAATCGGCGGGCCGGGCCGGCGGGTCGGTGAGCGCGG
CCCGGGCCGGACATGGCGGCGCTCTACGCCTGCACCAAGTGCCACCAGCGCTTCCCCTTCGAGGCGCTGTCTCAGGGGCAGCAGCTGTGC
AAGGAATGTCGGATTGCACACCCTGTTGTGAAGTGCACCTACTGCAGGACTGAGTACCAGCAGGAGAGTAAAACCAATACAATATGCAAG
AAATGTGCTCAGAACGTGCAGTTGTATGGAACGCCCAAACCTTGTCAGTATTGCAACATAATTGCAGCATTTATTGGGAATAAATGCCAG
CGCTGCACAAATTCAGAAAAGAAGTATGGACCACCCTATTCTTGTGAACAGTGCAAGCAGCAGTGTGCATTTGACAGGAAAGATGATAGA
AAGAAGGTAGATGGGAAATTGCTGTGCTGGCTGTGCACACTTTCATACAAACGGGTCCTTCAGAAGACCAAAGAGCAGAGGAAACACCTG
AGTAGCTCTTCTCGTGCTGGCCACCAGGAGAAGGAGCAGTATAGTCGCCTGAGTGGTGGTGGCCATTATAACAGCCAGAAAACACTTTCT
ACATCTTCAATTCAAAATGAAATCCCAAAGAAAAAGTCCAAGTTTGAGTCAATCACAACTAATGGAGACAGCAACGCTCAGTATATCGTC
AGTGGCTCTGACGATGGCTCCTTCTTCATCTGGGAAAAGGAGACCACCAACCTGGTCCGTGTGCTCCAAGGGGATGAGTCCATTGTCAAC
TGCCTGCAGCCACACCCCAGCTACTGCTTCCTGGCCACCAGTGGCATCGATCCTGTTGTGCGGCTCTGGAACCCCCGACCAGAGAGTGAA
GACCTCACAGGCCGAGTCGTGGAAGATATGGAGGGTGCTTCACAGGCCAACCAGCGGCGCATGAATGCAGACCCGTTGGAGGTGATGCTG
CTCAACATGGGCTACCGGATCACGGGCCTGAGCAGTGGGGGTGCCGGGGCCTCTGATGATGAGGACAGCTCTGAGGGCCAGGTGCAGTGC
CGGCCCAGCTAGACCCTCCAGCCCTGGTCCCCAGCCCCTGCTACTGGCTGGACCCTCTGCCCTGGGCAGGAGGTCAGGGGATTCTGTTTT
GGTTTGTCTTCCCCACCACCCTTTTTTTTCATTTCCCCTGTTTTGTTTGTTAGTTTGGCGTTAGGGGTGGAGGTTGCTACAACTTGCTGG
CTTTCGGACTCTGGGCTGATTGTCCCCTGACTATCCCCAGCCCTGAAAAAAAGAGCAGGAGGGGACACCCCTCCATATGCCCCCCCCCAT
CTCCTGCTTTCATGTCCCTGGAGGGCTCTGGCCTGCCTCAAAACCCCTTCTGCCTCAGGTGGGGAGGAACAAGCTGAACTGTCTTCAGGG
ACTGTCCTGCCCTTTAGCTGGCAGCAGCAGGAGGAGTGGGATTCCCAATTGGTAAGGGCTCGCCTTGGCCTGTTGCCACTCTTGCTCCCT
AGCCTGCAAGGCTAGCTCCCCTGTGGTCTTCAGGAAAGGTTTTGAAAAAGGATGGGTCCCACCCTCCCTCCAGAGCCACCAGTGTTAGAG
CGGAGCCCAAAGGAAGGATGGGAGCCCTGGAGTGGGCAAGACCAGGCCACCTGCTGAGGTCGCTGTGGAGCACCCTCGCTCCTCTCCTGG
CTACTAGCTCTGGCCCTGCACCTACTCTCACTGGCCACCTCTGGAGGCTCTGCCTTTCCCAAGGGCCCTGGCAGAGGGTGGGGCACTGCA
CCTTACCCCACCCATCCATGCCAGCACTTCTGCACTACGGCCATTCTCCTCTTGGGCGCTCCTCAGCCTCACTGTGACCTTTCTGCCAGA
GCTCCCAGCCAGGCCTACTCTGCTGAGGTGGCGCTTCCTGCTAAGGGCCCTTCTCTGCCCTTTCTGCCCTCCTTCCCATCCCACATGCTG
AGCCGCCACAAAGACCAAAGAAGTGATGGCTTTTCTCTGTCCCCTGCTGCTCTGAGGGGAGAGGGGTGGGTCTCCTGAGCCACTCAGATG
GGAAAGTCCCTTACTCGGCCCCTCCCTCCCCAGCAGCCCCAAGCTTTACACTGGATGCAGCGATCAACCCACCACTCACCAGGCCTCTCC
TCCCCTCTGCCCCCGGCTCTTAGCTCCAGCTGCTCCAGGTAGTTGGTTCATCCTTCCCCCTCTCTCCCTCCCTGCTTCCCCTTCAGTGCT
TACTTGGCTCCAGCCCTCCAGCTGCAGCCCCTGGGGAAAAGCAGCCTCCCTTCTCCTCTCCCTCCACTCCCTCGCTCCCTCCCTCAGCCC
CTGTCTCTGCCAGGTGCCTCCTCTCAGTCAGGCTTCAGAGCAGCCCTGGAGACAGGAGGGCCATGTTAAAAGCTTTTTCACAGTTTTAAG
AAGACAAGTGGAGGGTGAGGATAGTGGTGGGGGGTCTGGCACCATCTCATTGCTTTAATCCCAGCAACACAGGTGGCAGCTTCTCCCCCT
TCCTTCCCACCCCAGTCCCTCTTCCCACCCCTCTCTTCTAGCTTGGTAATGAAGTATATTTATTGGTGAAGGAAACAGCTGCTGCTGCTT
CTCCTGCTGCTGGGACCTGCTCCCCTGTCTCTTCTCCGTGACCTTTCTCTAGCCAGGGAGAAGGGAGAGCAGGAGTATTGGGGCTGGGCC
CTGGGGCCCAAGGACCAGCTGGGTCCCCTTTGCTTTCTTGTGTTCCAGCCACCTGCCATTTCCTCCCTGCCTCCCACCCTCCCTCCCTGC
CCCCTGTCCTGCTTCCCACCCCCTGCCTGCCCAGCCTGGGCCCTGCAGTGTGGAGAGACACATAAGCCTTACTGTCCTCTGGGGGCAGGA
GCCGAGCCTTTTTGTTGCTCCGCTCCCAGGAGAGTGAGGGTGACGCAATTGATTAAAACCATTTTGTTCTAGGTGTGGCTGGTGGCATTT
GTGGGGTGCAGATGGGTCTTGGAACCAAAGTGAGGGCACCTGGTCCCTCACCTCTGTAGCTCTATGACTTAGTAACCACACCTCTACTGG
ACAGAATGAGGCCTGCCTTGAAGGGTCACCGTGAGCAGCGGCCACCCAGCCCAGCAGGGCTGAGTGCAGAGCCCAGCTCTCATGGCTGTG
ATTTGTAATCATCAGCTTTCACTCTCTGGCTGTTTTCTCATCAGTAAAATAAGGGACTTGGAATCTTAGTGGTTTTTCAAACCATTTTAC

>In-frame_ENST00000373954_ENST00000319394_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(amino acids)=329AA_start in transcript=102_stop in transcript=1091
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTN
SEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI
QNEIPKKKSKFESITTNGDSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPHPSYCFLATSGIDPVVRLWNPRPESEDLTG

--------------------------------------------------------------
>In-frame_ENST00000373954_ENST00000361771_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(transcript)=2953nt_BP=701nt
GCCGCAGCCAGCAGCCTGCAGCCGCCGCCGGGTTGTGCCTCAGACTGTCAGATAAATCGGCGGGCCGGGCCGGCGGGTCGGTGAGCGCGG
CCCGGGCCGGACATGGCGGCGCTCTACGCCTGCACCAAGTGCCACCAGCGCTTCCCCTTCGAGGCGCTGTCTCAGGGGCAGCAGCTGTGC
AAGGAATGTCGGATTGCACACCCTGTTGTGAAGTGCACCTACTGCAGGACTGAGTACCAGCAGGAGAGTAAAACCAATACAATATGCAAG
AAATGTGCTCAGAACGTGCAGTTGTATGGAACGCCCAAACCTTGTCAGTATTGCAACATAATTGCAGCATTTATTGGGAATAAATGCCAG
CGCTGCACAAATTCAGAAAAGAAGTATGGACCACCCTATTCTTGTGAACAGTGCAAGCAGCAGTGTGCATTTGACAGGAAAGATGATAGA
AAGAAGGTAGATGGGAAATTGCTGTGCTGGCTGTGCACACTTTCATACAAACGGGTCCTTCAGAAGACCAAAGAGCAGAGGAAACACCTG
AGTAGCTCTTCTCGTGCTGGCCACCAGGAGAAGGAGCAGTATAGTCGCCTGAGTGGTGGTGGCCATTATAACAGCCAGAAAACACTTTCT
ACATCTTCAATTCAAAATGAAATCCCAAAGAAAAAGTCCAAGTTTGAGTCAATCACAACTAATGGAGACAGCAACGCTCAGTATATCGTC
AGTGGCTCTGACGATGGCTCCTTCTTCATCTGGGAAAAGGAGACCACCAACCTGGTCCGTGTGCTCCAAGGGGATGAGTCCATTGTCAAC
TGCCTGCAGCCACACCCCAGCTACTGCTTCCTGGCCACCAGTGGCATCGATCCTGTTGTGCGGCTCTGGAACCCCCGACCAGAGAGTGAA
GACCTCACAGGCCGAGTCGTGGAAGATATGGAGGGTGCTTCACAGGCCAACCAGCGGCGCATGAATGCAGACCCGTTGGAGGTGATGCTG
CTCAACATGGGCTACCGGATCACGGGCCTGAGCAGTGGGGGTGCCGGGGCCTCTGATGATGAGGACAGCTCTGAGGGCCAGGTGCAGTGC
CGGCCCAGCTAGACCCTCCAGCCCTGGTCCCCAGCCCCTGCTACTGGCTGGACCCTCTGCCCTGGGCAGGAGGTCAGGGGATTCTGTTTT
GGTTTGTCTTCCCCACCACCCTTTTTTTTCATTTCCCCTGTTTTGTTTGTTAGTTTGGCGTTAGGGGTGGAGGTTGCTACAACTTGCTGG
CTTTCGGACTCTGGGCTGATTGTCCCCTGACTATCCCCAGCCCTGAAAAAAAGAGCAGGAGGGGACACCCCTCCATATGCCCCCCCCCAT
CTCCTGCTTTCATGTCCCTGGAGGGCTCTGGCCTGCCTCAAAACCCCTTCTGCCTCAGGTGGGGAGGAACAAGCTGAACTGTCTTCAGGG
ACTGTCCTGCCCTTTAGCTGGCAGCAGCAGGAGGAGTGGGATTCCCAATTGGTAAGGGCTCGCCTTGGCCTGTTGCCACTCTTGCTCCCT
AGCCTGCAAGGCTAGCTCCCCTGTGGTCTTCAGGAAAGGTTTTGAAAAAGGATGGGTCCCACCCTCCCTCCAGAGCCACCAGTGTTAGAG
CGGAGCCCAAAGGAAGGATGGGAGCCCTGGAGTGGGCAAGACCAGGCCACCTGCTGAGGTCGCTGTGGAGCACCCTCGCTCCTCTCCTGG
CTACTAGCTCTGGCCCTGCACCTACTCTCACTGGCCACCTCTGGAGGCTCTGCCTTTCCCAAGGGCCCTGGCAGAGGGTGGGGCACTGCA
CCTTACCCCACCCATCCATGCCAGCACTTCTGCACTACGGCCATTCTCCTCTTGGGCGCTCCTCAGCCTCACTGTGACCTTTCTGCCAGA
GCTCCCAGCCAGGCCTACTCTGCTGAGGTGGCGCTTCCTGCTAAGGGCCCTTCTCTGCCCTTTCTGCCCTCCTTCCCATCCCACATGCTG
AGCCGCCACAAAGACCAAAGAAGTGATGGCTTTTCTCTGTCCCCTGCTGCTCTGAGGGGAGAGGGGTGGGTCTCCTGAGCCACTCAGATG
GGAAAGTCCCTTACTCGGCCCCTCCCTCCCCAGCAGCCCCAAGCTTTACACTGGATGCAGCGATCAACCCACCACTCACCAGGCCTCTCC
TCCCCTCTGCCCCCGGCTCTTAGCTCCAGCTGCTCCAGGTAGTTGGTTCATCCTTCCCCCTCTCTCCCTCCCTGCTTCCCCTTCAGTGCT
TACTTGGCTCCAGCCCTCCAGCTGCAGCCCCTGGGGAAAAGCAGCCTCCCTTCTCCTCTCCCTCCACTCCCTCGCTCCCTCCCTCAGCCC
CTGTCTCTGCCAGGTGCCTCCTCTCAGTCAGGCTTCAGAGCAGCCCTGGAGACAGGAGGGCCATGTTAAAAGCTTTTTCACAGTTTTAAG
AAGACAAGTGGAGGGTGAGGATAGTGGTGGGGGGTCTGGCACCATCTCATTGCTTTAATCCCAGCAACACAGGTGGCAGCTTCTCCCCCT
TCCTTCCCACCCCAGTCCCTCTTCCCACCCCTCTCTTCTAGCTTGGTAATGAAGTATATTTATTGGTGAAGGAAACAGCTGCTGCTGCTT
CTCCTGCTGCTGGGACCTGCTCCCCTGTCTCTTCTCCGTGACCTTTCTCTAGCCAGGGAGAAGGGAGAGCAGGAGTATTGGGGCTGGGCC
CTGGGGCCCAAGGACCAGCTGGGTCCCCTTTGCTTTCTTGTGTTCCAGCCACCTGCCATTTCCTCCCTGCCTCCCACCCTCCCTCCCTGC
CCCCTGTCCTGCTTCCCACCCCCTGCCTGCCCAGCCTGGGCCCTGCAGTGTGGAGAGACACATAAGCCTTACTGTCCTCTGGGGGCAGGA

>In-frame_ENST00000373954_ENST00000361771_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(amino acids)=329AA_start in transcript=102_stop in transcript=1091
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTN
SEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI
QNEIPKKKSKFESITTNGDSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPHPSYCFLATSGIDPVVRLWNPRPESEDLTG

--------------------------------------------------------------
>In-frame_ENST00000530324_ENST00000319394_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(transcript)=3279nt_BP=652nt
AGATAAATCGGCGGGCCGGGCCGGCGGGTCGGTGAGCGCGGCCCGGGCCGGACATGGCGGCGCTCTACGCCTGCACCAAGTGCCACCAGC
GCTTCCCCTTCGAGGCGCTGTCTCAGGGGCAGCAGCTGTGCAAGGAATGTCGGATTGCACACCCTGTTGTGAAGTGCACCTACTGCAGGA
CTGAGTACCAGCAGGAGAGTAAAACCAATACAATATGCAAGAAATGTGCTCAGAACGTGCAGTTGTATGGAACGCCCAAACCTTGTCAGT
ATTGCAACATAATTGCAGCATTTATTGGGAATAAATGCCAGCGCTGCACAAATTCAGAAAAGAAGTATGGACCACCCTATTCTTGTGAAC
AGTGCAAGCAGCAGTGTGCATTTGACAGGAAAGATGATAGAAAGAAGGTAGATGGGAAATTGCTGTGCTGGCTGTGCACACTTTCATACA
AACGGGTCCTTCAGAAGACCAAAGAGCAGAGGAAACACCTGAGTAGCTCTTCTCGTGCTGGCCACCAGGAGAAGGAGCAGTATAGTCGCC
TGAGTGGTGGTGGCCATTATAACAGCCAGAAAACACTTTCTACATCTTCAATTCAAAATGAAATCCCAAAGAAAAAGTCCAAGTTTGAGT
CAATCACAACTAATGGAGACAGCAACGCTCAGTATATCGTCAGTGGCTCTGACGATGGCTCCTTCTTCATCTGGGAAAAGGAGACCACCA
ACCTGGTCCGTGTGCTCCAAGGGGATGAGTCCATTGTCAACTGCCTGCAGCCACACCCCAGCTACTGCTTCCTGGCCACCAGTGGCATCG
ATCCTGTTGTGCGGCTCTGGAACCCCCGACCAGAGAGTGAAGACCTCACAGGCCGAGTCGTGGAAGATATGGAGGGTGCTTCACAGGCCA
ACCAGCGGCGCATGAATGCAGACCCGTTGGAGGTGATGCTGCTCAACATGGGCTACCGGATCACGGGCCTGAGCAGTGGGGGTGCCGGGG
CCTCTGATGATGAGGACAGCTCTGAGGGCCAGGTGCAGTGCCGGCCCAGCTAGACCCTCCAGCCCTGGTCCCCAGCCCCTGCTACTGGCT
GGACCCTCTGCCCTGGGCAGGAGGTCAGGGGATTCTGTTTTGGTTTGTCTTCCCCACCACCCTTTTTTTTCATTTCCCCTGTTTTGTTTG
TTAGTTTGGCGTTAGGGGTGGAGGTTGCTACAACTTGCTGGCTTTCGGACTCTGGGCTGATTGTCCCCTGACTATCCCCAGCCCTGAAAA
AAAGAGCAGGAGGGGACACCCCTCCATATGCCCCCCCCCATCTCCTGCTTTCATGTCCCTGGAGGGCTCTGGCCTGCCTCAAAACCCCTT
CTGCCTCAGGTGGGGAGGAACAAGCTGAACTGTCTTCAGGGACTGTCCTGCCCTTTAGCTGGCAGCAGCAGGAGGAGTGGGATTCCCAAT
TGGTAAGGGCTCGCCTTGGCCTGTTGCCACTCTTGCTCCCTAGCCTGCAAGGCTAGCTCCCCTGTGGTCTTCAGGAAAGGTTTTGAAAAA
GGATGGGTCCCACCCTCCCTCCAGAGCCACCAGTGTTAGAGCGGAGCCCAAAGGAAGGATGGGAGCCCTGGAGTGGGCAAGACCAGGCCA
CCTGCTGAGGTCGCTGTGGAGCACCCTCGCTCCTCTCCTGGCTACTAGCTCTGGCCCTGCACCTACTCTCACTGGCCACCTCTGGAGGCT
CTGCCTTTCCCAAGGGCCCTGGCAGAGGGTGGGGCACTGCACCTTACCCCACCCATCCATGCCAGCACTTCTGCACTACGGCCATTCTCC
TCTTGGGCGCTCCTCAGCCTCACTGTGACCTTTCTGCCAGAGCTCCCAGCCAGGCCTACTCTGCTGAGGTGGCGCTTCCTGCTAAGGGCC
CTTCTCTGCCCTTTCTGCCCTCCTTCCCATCCCACATGCTGAGCCGCCACAAAGACCAAAGAAGTGATGGCTTTTCTCTGTCCCCTGCTG
CTCTGAGGGGAGAGGGGTGGGTCTCCTGAGCCACTCAGATGGGAAAGTCCCTTACTCGGCCCCTCCCTCCCCAGCAGCCCCAAGCTTTAC
ACTGGATGCAGCGATCAACCCACCACTCACCAGGCCTCTCCTCCCCTCTGCCCCCGGCTCTTAGCTCCAGCTGCTCCAGGTAGTTGGTTC
ATCCTTCCCCCTCTCTCCCTCCCTGCTTCCCCTTCAGTGCTTACTTGGCTCCAGCCCTCCAGCTGCAGCCCCTGGGGAAAAGCAGCCTCC
CTTCTCCTCTCCCTCCACTCCCTCGCTCCCTCCCTCAGCCCCTGTCTCTGCCAGGTGCCTCCTCTCAGTCAGGCTTCAGAGCAGCCCTGG
AGACAGGAGGGCCATGTTAAAAGCTTTTTCACAGTTTTAAGAAGACAAGTGGAGGGTGAGGATAGTGGTGGGGGGTCTGGCACCATCTCA
TTGCTTTAATCCCAGCAACACAGGTGGCAGCTTCTCCCCCTTCCTTCCCACCCCAGTCCCTCTTCCCACCCCTCTCTTCTAGCTTGGTAA
TGAAGTATATTTATTGGTGAAGGAAACAGCTGCTGCTGCTTCTCCTGCTGCTGGGACCTGCTCCCCTGTCTCTTCTCCGTGACCTTTCTC
TAGCCAGGGAGAAGGGAGAGCAGGAGTATTGGGGCTGGGCCCTGGGGCCCAAGGACCAGCTGGGTCCCCTTTGCTTTCTTGTGTTCCAGC
CACCTGCCATTTCCTCCCTGCCTCCCACCCTCCCTCCCTGCCCCCTGTCCTGCTTCCCACCCCCTGCCTGCCCAGCCTGGGCCCTGCAGT
GTGGAGAGACACATAAGCCTTACTGTCCTCTGGGGGCAGGAGCCGAGCCTTTTTGTTGCTCCGCTCCCAGGAGAGTGAGGGTGACGCAAT
TGATTAAAACCATTTTGTTCTAGGTGTGGCTGGTGGCATTTGTGGGGTGCAGATGGGTCTTGGAACCAAAGTGAGGGCACCTGGTCCCTC
ACCTCTGTAGCTCTATGACTTAGTAACCACACCTCTACTGGACAGAATGAGGCCTGCCTTGAAGGGTCACCGTGAGCAGCGGCCACCCAG
CCCAGCAGGGCTGAGTGCAGAGCCCAGCTCTCATGGCTGTGATTTGTAATCATCAGCTTTCACTCTCTGGCTGTTTTCTCATCAGTAAAA
TAAGGGACTTGGAATCTTAGTGGTTTTTCAAACCATTTTACATTGTGACCCAATATACACATGATTACTTGTAGATATGTGTGTGTGTAT

>In-frame_ENST00000530324_ENST00000319394_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(amino acids)=329AA_start in transcript=53_stop in transcript=1042
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTN
SEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI
QNEIPKKKSKFESITTNGDSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPHPSYCFLATSGIDPVVRLWNPRPESEDLTG

--------------------------------------------------------------
>In-frame_ENST00000530324_ENST00000361771_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(transcript)=2904nt_BP=652nt
AGATAAATCGGCGGGCCGGGCCGGCGGGTCGGTGAGCGCGGCCCGGGCCGGACATGGCGGCGCTCTACGCCTGCACCAAGTGCCACCAGC
GCTTCCCCTTCGAGGCGCTGTCTCAGGGGCAGCAGCTGTGCAAGGAATGTCGGATTGCACACCCTGTTGTGAAGTGCACCTACTGCAGGA
CTGAGTACCAGCAGGAGAGTAAAACCAATACAATATGCAAGAAATGTGCTCAGAACGTGCAGTTGTATGGAACGCCCAAACCTTGTCAGT
ATTGCAACATAATTGCAGCATTTATTGGGAATAAATGCCAGCGCTGCACAAATTCAGAAAAGAAGTATGGACCACCCTATTCTTGTGAAC
AGTGCAAGCAGCAGTGTGCATTTGACAGGAAAGATGATAGAAAGAAGGTAGATGGGAAATTGCTGTGCTGGCTGTGCACACTTTCATACA
AACGGGTCCTTCAGAAGACCAAAGAGCAGAGGAAACACCTGAGTAGCTCTTCTCGTGCTGGCCACCAGGAGAAGGAGCAGTATAGTCGCC
TGAGTGGTGGTGGCCATTATAACAGCCAGAAAACACTTTCTACATCTTCAATTCAAAATGAAATCCCAAAGAAAAAGTCCAAGTTTGAGT
CAATCACAACTAATGGAGACAGCAACGCTCAGTATATCGTCAGTGGCTCTGACGATGGCTCCTTCTTCATCTGGGAAAAGGAGACCACCA
ACCTGGTCCGTGTGCTCCAAGGGGATGAGTCCATTGTCAACTGCCTGCAGCCACACCCCAGCTACTGCTTCCTGGCCACCAGTGGCATCG
ATCCTGTTGTGCGGCTCTGGAACCCCCGACCAGAGAGTGAAGACCTCACAGGCCGAGTCGTGGAAGATATGGAGGGTGCTTCACAGGCCA
ACCAGCGGCGCATGAATGCAGACCCGTTGGAGGTGATGCTGCTCAACATGGGCTACCGGATCACGGGCCTGAGCAGTGGGGGTGCCGGGG
CCTCTGATGATGAGGACAGCTCTGAGGGCCAGGTGCAGTGCCGGCCCAGCTAGACCCTCCAGCCCTGGTCCCCAGCCCCTGCTACTGGCT
GGACCCTCTGCCCTGGGCAGGAGGTCAGGGGATTCTGTTTTGGTTTGTCTTCCCCACCACCCTTTTTTTTCATTTCCCCTGTTTTGTTTG
TTAGTTTGGCGTTAGGGGTGGAGGTTGCTACAACTTGCTGGCTTTCGGACTCTGGGCTGATTGTCCCCTGACTATCCCCAGCCCTGAAAA
AAAGAGCAGGAGGGGACACCCCTCCATATGCCCCCCCCCATCTCCTGCTTTCATGTCCCTGGAGGGCTCTGGCCTGCCTCAAAACCCCTT
CTGCCTCAGGTGGGGAGGAACAAGCTGAACTGTCTTCAGGGACTGTCCTGCCCTTTAGCTGGCAGCAGCAGGAGGAGTGGGATTCCCAAT
TGGTAAGGGCTCGCCTTGGCCTGTTGCCACTCTTGCTCCCTAGCCTGCAAGGCTAGCTCCCCTGTGGTCTTCAGGAAAGGTTTTGAAAAA
GGATGGGTCCCACCCTCCCTCCAGAGCCACCAGTGTTAGAGCGGAGCCCAAAGGAAGGATGGGAGCCCTGGAGTGGGCAAGACCAGGCCA
CCTGCTGAGGTCGCTGTGGAGCACCCTCGCTCCTCTCCTGGCTACTAGCTCTGGCCCTGCACCTACTCTCACTGGCCACCTCTGGAGGCT
CTGCCTTTCCCAAGGGCCCTGGCAGAGGGTGGGGCACTGCACCTTACCCCACCCATCCATGCCAGCACTTCTGCACTACGGCCATTCTCC
TCTTGGGCGCTCCTCAGCCTCACTGTGACCTTTCTGCCAGAGCTCCCAGCCAGGCCTACTCTGCTGAGGTGGCGCTTCCTGCTAAGGGCC
CTTCTCTGCCCTTTCTGCCCTCCTTCCCATCCCACATGCTGAGCCGCCACAAAGACCAAAGAAGTGATGGCTTTTCTCTGTCCCCTGCTG
CTCTGAGGGGAGAGGGGTGGGTCTCCTGAGCCACTCAGATGGGAAAGTCCCTTACTCGGCCCCTCCCTCCCCAGCAGCCCCAAGCTTTAC
ACTGGATGCAGCGATCAACCCACCACTCACCAGGCCTCTCCTCCCCTCTGCCCCCGGCTCTTAGCTCCAGCTGCTCCAGGTAGTTGGTTC
ATCCTTCCCCCTCTCTCCCTCCCTGCTTCCCCTTCAGTGCTTACTTGGCTCCAGCCCTCCAGCTGCAGCCCCTGGGGAAAAGCAGCCTCC
CTTCTCCTCTCCCTCCACTCCCTCGCTCCCTCCCTCAGCCCCTGTCTCTGCCAGGTGCCTCCTCTCAGTCAGGCTTCAGAGCAGCCCTGG
AGACAGGAGGGCCATGTTAAAAGCTTTTTCACAGTTTTAAGAAGACAAGTGGAGGGTGAGGATAGTGGTGGGGGGTCTGGCACCATCTCA
TTGCTTTAATCCCAGCAACACAGGTGGCAGCTTCTCCCCCTTCCTTCCCACCCCAGTCCCTCTTCCCACCCCTCTCTTCTAGCTTGGTAA
TGAAGTATATTTATTGGTGAAGGAAACAGCTGCTGCTGCTTCTCCTGCTGCTGGGACCTGCTCCCCTGTCTCTTCTCCGTGACCTTTCTC
TAGCCAGGGAGAAGGGAGAGCAGGAGTATTGGGGCTGGGCCCTGGGGCCCAAGGACCAGCTGGGTCCCCTTTGCTTTCTTGTGTTCCAGC
CACCTGCCATTTCCTCCCTGCCTCCCACCCTCCCTCCCTGCCCCCTGTCCTGCTTCCCACCCCCTGCCTGCCCAGCCTGGGCCCTGCAGT
GTGGAGAGACACATAAGCCTTACTGTCCTCTGGGGGCAGGAGCCGAGCCTTTTTGTTGCTCCGCTCCCAGGAGAGTGAGGGTGACGCAAT

>In-frame_ENST00000530324_ENST00000361771_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(amino acids)=329AA_start in transcript=53_stop in transcript=1042
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTN
SEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI
QNEIPKKKSKFESITTNGDSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPHPSYCFLATSGIDPVVRLWNPRPESEDLTG

--------------------------------------------------------------
>In-frame_ENST00000010299_ENST00000319394_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(transcript)=3352nt_BP=725nt
CGGTGAGCGCGGCCCGGGCCGGACATGGCGGCGCTCTACGCCTGCACCAAGTGCCACCAGCGCTTCCCCTTCGAGGCGCTGTCTCAGGGG
CAGCAGCTGTGCAAGGAATGTCGGATTGCACACCCTGTTGTGAAGTGCACCTACTGCAGGACTGAGTACCAGCAGGAGAGGCTAGAGTGC
AATGGCACGATCTCGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCTCATCCTCCCGAGTAGCTGGGATTACAGGC
ATTAAAACCAATACAATATGCAAGAAATGTGCTCAGAACGTGCAGTTGTATGGAACGCCCAAACCTTGTCAGTATTGCAACATAATTGCA
GCATTTATTGGGAATAAATGCCAGCGCTGCACAAATTCAGAAAAGAAGTATGGACCACCCTATTCTTGTGAACAGTGCAAGCAGCAGTGT
GCATTTGACAGGAAAGATGATAGAAAGAAGGTAGATGGGAAATTGCTGTGCTGGCTGTGCACACTTTCATACAAACGGGTCCTTCAGAAG
ACCAAAGAGCAGAGGAAACACCTGAGTAGCTCTTCTCGTGCTGGCCACCAGGAGAAGGAGCAGTATAGTCGCCTGAGTGGTGGTGGCCAT
TATAACAGCCAGAAAACACTTTCTACATCTTCAATTCAAAATGAAATCCCAAAGAAAAAGTCCAAGTTTGAGTCAATCACAACTAATGGA
GACAGCAACGCTCAGTATATCGTCAGTGGCTCTGACGATGGCTCCTTCTTCATCTGGGAAAAGGAGACCACCAACCTGGTCCGTGTGCTC
CAAGGGGATGAGTCCATTGTCAACTGCCTGCAGCCACACCCCAGCTACTGCTTCCTGGCCACCAGTGGCATCGATCCTGTTGTGCGGCTC
TGGAACCCCCGACCAGAGAGTGAAGACCTCACAGGCCGAGTCGTGGAAGATATGGAGGGTGCTTCACAGGCCAACCAGCGGCGCATGAAT
GCAGACCCGTTGGAGGTGATGCTGCTCAACATGGGCTACCGGATCACGGGCCTGAGCAGTGGGGGTGCCGGGGCCTCTGATGATGAGGAC
AGCTCTGAGGGCCAGGTGCAGTGCCGGCCCAGCTAGACCCTCCAGCCCTGGTCCCCAGCCCCTGCTACTGGCTGGACCCTCTGCCCTGGG
CAGGAGGTCAGGGGATTCTGTTTTGGTTTGTCTTCCCCACCACCCTTTTTTTTCATTTCCCCTGTTTTGTTTGTTAGTTTGGCGTTAGGG
GTGGAGGTTGCTACAACTTGCTGGCTTTCGGACTCTGGGCTGATTGTCCCCTGACTATCCCCAGCCCTGAAAAAAAGAGCAGGAGGGGAC
ACCCCTCCATATGCCCCCCCCCATCTCCTGCTTTCATGTCCCTGGAGGGCTCTGGCCTGCCTCAAAACCCCTTCTGCCTCAGGTGGGGAG
GAACAAGCTGAACTGTCTTCAGGGACTGTCCTGCCCTTTAGCTGGCAGCAGCAGGAGGAGTGGGATTCCCAATTGGTAAGGGCTCGCCTT
GGCCTGTTGCCACTCTTGCTCCCTAGCCTGCAAGGCTAGCTCCCCTGTGGTCTTCAGGAAAGGTTTTGAAAAAGGATGGGTCCCACCCTC
CCTCCAGAGCCACCAGTGTTAGAGCGGAGCCCAAAGGAAGGATGGGAGCCCTGGAGTGGGCAAGACCAGGCCACCTGCTGAGGTCGCTGT
GGAGCACCCTCGCTCCTCTCCTGGCTACTAGCTCTGGCCCTGCACCTACTCTCACTGGCCACCTCTGGAGGCTCTGCCTTTCCCAAGGGC
CCTGGCAGAGGGTGGGGCACTGCACCTTACCCCACCCATCCATGCCAGCACTTCTGCACTACGGCCATTCTCCTCTTGGGCGCTCCTCAG
CCTCACTGTGACCTTTCTGCCAGAGCTCCCAGCCAGGCCTACTCTGCTGAGGTGGCGCTTCCTGCTAAGGGCCCTTCTCTGCCCTTTCTG
CCCTCCTTCCCATCCCACATGCTGAGCCGCCACAAAGACCAAAGAAGTGATGGCTTTTCTCTGTCCCCTGCTGCTCTGAGGGGAGAGGGG
TGGGTCTCCTGAGCCACTCAGATGGGAAAGTCCCTTACTCGGCCCCTCCCTCCCCAGCAGCCCCAAGCTTTACACTGGATGCAGCGATCA
ACCCACCACTCACCAGGCCTCTCCTCCCCTCTGCCCCCGGCTCTTAGCTCCAGCTGCTCCAGGTAGTTGGTTCATCCTTCCCCCTCTCTC
CCTCCCTGCTTCCCCTTCAGTGCTTACTTGGCTCCAGCCCTCCAGCTGCAGCCCCTGGGGAAAAGCAGCCTCCCTTCTCCTCTCCCTCCA
CTCCCTCGCTCCCTCCCTCAGCCCCTGTCTCTGCCAGGTGCCTCCTCTCAGTCAGGCTTCAGAGCAGCCCTGGAGACAGGAGGGCCATGT
TAAAAGCTTTTTCACAGTTTTAAGAAGACAAGTGGAGGGTGAGGATAGTGGTGGGGGGTCTGGCACCATCTCATTGCTTTAATCCCAGCA
ACACAGGTGGCAGCTTCTCCCCCTTCCTTCCCACCCCAGTCCCTCTTCCCACCCCTCTCTTCTAGCTTGGTAATGAAGTATATTTATTGG
TGAAGGAAACAGCTGCTGCTGCTTCTCCTGCTGCTGGGACCTGCTCCCCTGTCTCTTCTCCGTGACCTTTCTCTAGCCAGGGAGAAGGGA
GAGCAGGAGTATTGGGGCTGGGCCCTGGGGCCCAAGGACCAGCTGGGTCCCCTTTGCTTTCTTGTGTTCCAGCCACCTGCCATTTCCTCC
CTGCCTCCCACCCTCCCTCCCTGCCCCCTGTCCTGCTTCCCACCCCCTGCCTGCCCAGCCTGGGCCCTGCAGTGTGGAGAGACACATAAG
CCTTACTGTCCTCTGGGGGCAGGAGCCGAGCCTTTTTGTTGCTCCGCTCCCAGGAGAGTGAGGGTGACGCAATTGATTAAAACCATTTTG
TTCTAGGTGTGGCTGGTGGCATTTGTGGGGTGCAGATGGGTCTTGGAACCAAAGTGAGGGCACCTGGTCCCTCACCTCTGTAGCTCTATG
ACTTAGTAACCACACCTCTACTGGACAGAATGAGGCCTGCCTTGAAGGGTCACCGTGAGCAGCGGCCACCCAGCCCAGCAGGGCTGAGTG
CAGAGCCCAGCTCTCATGGCTGTGATTTGTAATCATCAGCTTTCACTCTCTGGCTGTTTTCTCATCAGTAAAATAAGGGACTTGGAATCT
TAGTGGTTTTTCAAACCATTTTACATTGTGACCCAATATACACATGATTACTTGTAGATATGTGTGTGTGTATATATATATAAAAAAAAT

>In-frame_ENST00000010299_ENST00000319394_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(amino acids)=363AA_start in transcript=24_stop in transcript=1115
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQERLECNGTISAHCNLHLPGSSDSPASSSRVAGITGIKTNTICK
KCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL
SSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVN
CLQPHPSYCFLATSGIDPVVRLWNPRPESEDLTGRVVEDMEGASQANQRRMNADPLEVMLLNMGYRITGLSSGGAGASDDEDSSEGQVQC

--------------------------------------------------------------
>In-frame_ENST00000010299_ENST00000361771_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(transcript)=2977nt_BP=725nt
CGGTGAGCGCGGCCCGGGCCGGACATGGCGGCGCTCTACGCCTGCACCAAGTGCCACCAGCGCTTCCCCTTCGAGGCGCTGTCTCAGGGG
CAGCAGCTGTGCAAGGAATGTCGGATTGCACACCCTGTTGTGAAGTGCACCTACTGCAGGACTGAGTACCAGCAGGAGAGGCTAGAGTGC
AATGGCACGATCTCGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCTCATCCTCCCGAGTAGCTGGGATTACAGGC
ATTAAAACCAATACAATATGCAAGAAATGTGCTCAGAACGTGCAGTTGTATGGAACGCCCAAACCTTGTCAGTATTGCAACATAATTGCA
GCATTTATTGGGAATAAATGCCAGCGCTGCACAAATTCAGAAAAGAAGTATGGACCACCCTATTCTTGTGAACAGTGCAAGCAGCAGTGT
GCATTTGACAGGAAAGATGATAGAAAGAAGGTAGATGGGAAATTGCTGTGCTGGCTGTGCACACTTTCATACAAACGGGTCCTTCAGAAG
ACCAAAGAGCAGAGGAAACACCTGAGTAGCTCTTCTCGTGCTGGCCACCAGGAGAAGGAGCAGTATAGTCGCCTGAGTGGTGGTGGCCAT
TATAACAGCCAGAAAACACTTTCTACATCTTCAATTCAAAATGAAATCCCAAAGAAAAAGTCCAAGTTTGAGTCAATCACAACTAATGGA
GACAGCAACGCTCAGTATATCGTCAGTGGCTCTGACGATGGCTCCTTCTTCATCTGGGAAAAGGAGACCACCAACCTGGTCCGTGTGCTC
CAAGGGGATGAGTCCATTGTCAACTGCCTGCAGCCACACCCCAGCTACTGCTTCCTGGCCACCAGTGGCATCGATCCTGTTGTGCGGCTC
TGGAACCCCCGACCAGAGAGTGAAGACCTCACAGGCCGAGTCGTGGAAGATATGGAGGGTGCTTCACAGGCCAACCAGCGGCGCATGAAT
GCAGACCCGTTGGAGGTGATGCTGCTCAACATGGGCTACCGGATCACGGGCCTGAGCAGTGGGGGTGCCGGGGCCTCTGATGATGAGGAC
AGCTCTGAGGGCCAGGTGCAGTGCCGGCCCAGCTAGACCCTCCAGCCCTGGTCCCCAGCCCCTGCTACTGGCTGGACCCTCTGCCCTGGG
CAGGAGGTCAGGGGATTCTGTTTTGGTTTGTCTTCCCCACCACCCTTTTTTTTCATTTCCCCTGTTTTGTTTGTTAGTTTGGCGTTAGGG
GTGGAGGTTGCTACAACTTGCTGGCTTTCGGACTCTGGGCTGATTGTCCCCTGACTATCCCCAGCCCTGAAAAAAAGAGCAGGAGGGGAC
ACCCCTCCATATGCCCCCCCCCATCTCCTGCTTTCATGTCCCTGGAGGGCTCTGGCCTGCCTCAAAACCCCTTCTGCCTCAGGTGGGGAG
GAACAAGCTGAACTGTCTTCAGGGACTGTCCTGCCCTTTAGCTGGCAGCAGCAGGAGGAGTGGGATTCCCAATTGGTAAGGGCTCGCCTT
GGCCTGTTGCCACTCTTGCTCCCTAGCCTGCAAGGCTAGCTCCCCTGTGGTCTTCAGGAAAGGTTTTGAAAAAGGATGGGTCCCACCCTC
CCTCCAGAGCCACCAGTGTTAGAGCGGAGCCCAAAGGAAGGATGGGAGCCCTGGAGTGGGCAAGACCAGGCCACCTGCTGAGGTCGCTGT
GGAGCACCCTCGCTCCTCTCCTGGCTACTAGCTCTGGCCCTGCACCTACTCTCACTGGCCACCTCTGGAGGCTCTGCCTTTCCCAAGGGC
CCTGGCAGAGGGTGGGGCACTGCACCTTACCCCACCCATCCATGCCAGCACTTCTGCACTACGGCCATTCTCCTCTTGGGCGCTCCTCAG
CCTCACTGTGACCTTTCTGCCAGAGCTCCCAGCCAGGCCTACTCTGCTGAGGTGGCGCTTCCTGCTAAGGGCCCTTCTCTGCCCTTTCTG
CCCTCCTTCCCATCCCACATGCTGAGCCGCCACAAAGACCAAAGAAGTGATGGCTTTTCTCTGTCCCCTGCTGCTCTGAGGGGAGAGGGG
TGGGTCTCCTGAGCCACTCAGATGGGAAAGTCCCTTACTCGGCCCCTCCCTCCCCAGCAGCCCCAAGCTTTACACTGGATGCAGCGATCA
ACCCACCACTCACCAGGCCTCTCCTCCCCTCTGCCCCCGGCTCTTAGCTCCAGCTGCTCCAGGTAGTTGGTTCATCCTTCCCCCTCTCTC
CCTCCCTGCTTCCCCTTCAGTGCTTACTTGGCTCCAGCCCTCCAGCTGCAGCCCCTGGGGAAAAGCAGCCTCCCTTCTCCTCTCCCTCCA
CTCCCTCGCTCCCTCCCTCAGCCCCTGTCTCTGCCAGGTGCCTCCTCTCAGTCAGGCTTCAGAGCAGCCCTGGAGACAGGAGGGCCATGT
TAAAAGCTTTTTCACAGTTTTAAGAAGACAAGTGGAGGGTGAGGATAGTGGTGGGGGGTCTGGCACCATCTCATTGCTTTAATCCCAGCA
ACACAGGTGGCAGCTTCTCCCCCTTCCTTCCCACCCCAGTCCCTCTTCCCACCCCTCTCTTCTAGCTTGGTAATGAAGTATATTTATTGG
TGAAGGAAACAGCTGCTGCTGCTTCTCCTGCTGCTGGGACCTGCTCCCCTGTCTCTTCTCCGTGACCTTTCTCTAGCCAGGGAGAAGGGA
GAGCAGGAGTATTGGGGCTGGGCCCTGGGGCCCAAGGACCAGCTGGGTCCCCTTTGCTTTCTTGTGTTCCAGCCACCTGCCATTTCCTCC
CTGCCTCCCACCCTCCCTCCCTGCCCCCTGTCCTGCTTCCCACCCCCTGCCTGCCCAGCCTGGGCCCTGCAGTGTGGAGAGACACATAAG
CCTTACTGTCCTCTGGGGGCAGGAGCCGAGCCTTTTTGTTGCTCCGCTCCCAGGAGAGTGAGGGTGACGCAATTGATTAAAACCATTTTG

>In-frame_ENST00000010299_ENST00000361771_TCGA-44-6778-01A_FAM76A_chr1_28075665_-_WDTC1_chr1_27631492_length(amino acids)=363AA_start in transcript=24_stop in transcript=1115
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQERLECNGTISAHCNLHLPGSSDSPASSSRVAGITGIKTNTICK
KCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL
SSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVN
CLQPHPSYCFLATSGIDPVVRLWNPRPESEDLTGRVVEDMEGASQANQRRMNADPLEVMLLNMGYRITGLSSGGAGASDDEDSSEGQVQC

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FAM76A-WDTC1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FAM76A-WDTC1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FAM76A-WDTC1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource