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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FAT1-DHX36 (FusionGDB2 ID:29370)

Fusion Gene Summary for FAT1-DHX36

check button Fusion gene summary
Fusion gene informationFusion gene name: FAT1-DHX36
Fusion gene ID: 29370
HgeneTgene
Gene symbol

FAT1

DHX36

Gene ID

2195

170506

Gene nameFAT atypical cadherin 1DEAH-box helicase 36
SynonymsCDHF7|CDHR8|FAT|ME5|hFat1DDX36|G4R1|MLEL1|RHAU
Cytomap

4q35.2

3q25.2

Type of geneprotein-codingprotein-coding
Descriptionprotocadherin Fat 1FAT tumor suppressor 1cadherin ME5cadherin family member 7cadherin-related family member 8cadherin-related tumor suppressor homologprotein fat homologATP-dependent DNA/RNA helicase DHX36ATP-dependent RNA helicase DHX36DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36DEAD/H box polypeptide 36DEAH (Asp-Glu-Ala-His) box polypeptide 36DEAH box protein 36G4 resolvase-1MLE-like protein 1RNA helicase as
Modification date2020031320200313
UniProtAcc

Q14517

Q9H2U1

Ensembl transtripts involved in fusion geneENST00000441802, ENST00000512347, 
ENST00000496811, ENST00000308361, 
ENST00000544526, ENST00000329463, 
Fusion gene scores* DoF score16 X 17 X 8=21767 X 8 X 3=168
# samples 208
** MAII scorelog2(20/2176*10)=-3.44360665147561
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/168*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FAT1 [Title/Abstract] AND DHX36 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFAT1(187560875)-DHX36(154001060), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneDHX36

GO:0010501

RNA secondary structure unwinding

18842585|20472641|21149580|21846770|22238380

TgeneDHX36

GO:0017148

negative regulation of translation

24369427

TgeneDHX36

GO:0034605

cellular response to heat

18854321

TgeneDHX36

GO:0044806

G-quadruplex DNA unwinding

16150737|18842585

TgeneDHX36

GO:0090669

telomerase RNA stabilization

22238380

TgeneDHX36

GO:1903843

cellular response to arsenite ion

18854321


check buttonFusion gene breakpoints across FAT1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across DHX36 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CG-4301FAT1chr4

187560875

-DHX36chr3

154001060

-


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Fusion Gene ORF analysis for FAT1-DHX36

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000441802ENST00000496811FAT1chr4

187560875

-DHX36chr3

154001060

-
In-frameENST00000441802ENST00000308361FAT1chr4

187560875

-DHX36chr3

154001060

-
In-frameENST00000441802ENST00000544526FAT1chr4

187560875

-DHX36chr3

154001060

-
In-frameENST00000441802ENST00000329463FAT1chr4

187560875

-DHX36chr3

154001060

-
intron-3CDSENST00000512347ENST00000496811FAT1chr4

187560875

-DHX36chr3

154001060

-
intron-3CDSENST00000512347ENST00000308361FAT1chr4

187560875

-DHX36chr3

154001060

-
intron-3CDSENST00000512347ENST00000544526FAT1chr4

187560875

-DHX36chr3

154001060

-
intron-3CDSENST00000512347ENST00000329463FAT1chr4

187560875

-DHX36chr3

154001060

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000441802FAT1chr4187560875-ENST00000496811DHX36chr3154001060-8212385221045861458
ENST00000441802FAT1chr4187560875-ENST00000308361DHX36chr3154001060-5090385221045861458
ENST00000441802FAT1chr4187560875-ENST00000544526DHX36chr3154001060-5089385221045861458
ENST00000441802FAT1chr4187560875-ENST00000329463DHX36chr3154001060-4587385221045861458

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000441802ENST00000496811FAT1chr4187560875-DHX36chr3154001060-0.0001240720.9998759
ENST00000441802ENST00000308361FAT1chr4187560875-DHX36chr3154001060-0.000231590.99976844
ENST00000441802ENST00000544526FAT1chr4187560875-DHX36chr3154001060-0.0002314350.99976856
ENST00000441802ENST00000329463FAT1chr4187560875-DHX36chr3154001060-0.0003368660.9996631

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Fusion Genomic Features for FAT1-DHX36


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FAT1-DHX36


check button Go to

FGviewer for the breakpoints of chr4:187560875-chr3:154001060

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FAT1

Q14517

DHX36

Q9H2U1

FUNCTION: [Protocadherin Fat 1]: Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact. {ECO:0000250}.FUNCTION: Multifunctional ATP-dependent helicase that unwinds G-quadruplex (G4) structures (PubMed:16150737, PubMed:18854321, PubMed:20472641, PubMed:21586581). Plays a role in many biological processes such as genomic integrity, gene expression regulations and as a sensor to initiate antiviral responses (PubMed:14731398, PubMed:18279852, PubMed:21993297, PubMed:22238380, PubMed:25579584). G4 structures correspond to helical structures containing guanine tetrads (By similarity). Binds with high affinity to and unwinds G4 structures that are formed in nucleic acids (G4-ADN and G4-RNA) (PubMed:16150737, PubMed:18842585, PubMed:20472641, PubMed:21586581, PubMed:24369427, PubMed:26195789). Plays a role in genomic integrity (PubMed:22238380). Converts the G4-RNA structure present in telomerase RNA template component (TREC) into a double-stranded RNA to promote P1 helix formation that acts as a template boundary ensuring accurate reverse transcription (PubMed:20472641, PubMed:21149580, PubMed:21846770, PubMed:22238380, PubMed:24151078, PubMed:25579584). Plays a role in transcriptional regulation (PubMed:21586581, PubMed:21993297). Resolves G4-DNA structures in promoters of genes, such as YY1, KIT/c-kit and ALPL and positively regulates their expression (PubMed:21993297). Plays a role in post-transcriptional regulation (PubMed:27940037). Unwinds a G4-RNA structure located in the 3'-UTR polyadenylation site of the pre-mRNA TP53 and stimulates TP53 pre-mRNA 3'-end processing in response to ultraviolet (UV)-induced DNA damage (PubMed:27940037). Binds to the precursor-microRNA-134 (pre-miR-134) terminal loop and regulates its transport into the synapto-dendritic compartment (By similarity). Involved in the pre-miR-134-dependent inhibition of target gene expression and the control of dendritic spine size (By similarity). Plays a role in the regulation of cytoplasmic mRNA translation and mRNA stability (PubMed:24369427, PubMed:26489465). Binds to both G4-RNA structures and alternative non-quadruplex-forming sequence within the 3'-UTR of the PITX1 mRNA regulating negatively PITX1 protein expression (PubMed:24369427). Binds to both G4-RNA structure in the 5'-UTR and AU-rich elements (AREs) localized in the 3'-UTR of NKX2-5 mRNA to either stimulate protein translation or induce mRNA decay in an ELAVL1-dependent manner, respectively (PubMed:26489465). Binds also to ARE sequences present in several mRNAs mediating exosome-mediated 3'-5' mRNA degradation (PubMed:14731398, PubMed:18279852). Involved in cytoplasmic urokinase-type plasminogen activator (uPA) mRNA decay (PubMed:14731398). Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines via the adapter molecule TICAM1 (By similarity). Required for early embryonic development and hematopoiesis. Involved in the regulation of cardioblast differentiation and proliferation during heart development. Involved in spermatogonia differentiation. May play a role in ossification (By similarity). {ECO:0000250|UniProtKB:D4A2Z8, ECO:0000250|UniProtKB:Q05B79, ECO:0000250|UniProtKB:Q8VHK9, ECO:0000269|PubMed:14731398, ECO:0000269|PubMed:16150737, ECO:0000269|PubMed:18279852, ECO:0000269|PubMed:18842585, ECO:0000269|PubMed:18854321, ECO:0000269|PubMed:20472641, ECO:0000269|PubMed:21149580, ECO:0000269|PubMed:21586581, ECO:0000269|PubMed:21846770, ECO:0000269|PubMed:21993297, ECO:0000269|PubMed:22238380, ECO:0000269|PubMed:24151078, ECO:0000269|PubMed:24369427, ECO:0000269|PubMed:25579584, ECO:0000269|PubMed:26195789, ECO:0000269|PubMed:26489465, ECO:0000269|PubMed:27940037}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4271035_11391214.04589.0DomainCadherin 9
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-427150_2571214.04589.0DomainCadherin 2
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-42735_1491214.04589.0DomainCadherin 1
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-427368_4631214.04589.0DomainCadherin 3
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-427464_5691214.04589.0DomainCadherin 4
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-427570_6731214.04589.0DomainCadherin 5
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-427718_8221214.04589.0DomainCadherin 6
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-427823_9271214.04589.0DomainCadherin 7
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-427928_10341214.04589.0DomainCadherin 8
TgeneDHX36chr4:187560875chr3:154001060ENST000003083611724841_905735.0980.0RegionOB-fold-like subdomains
TgeneDHX36chr4:187560875chr3:154001060ENST000003294631825841_905750.0995.0RegionOB-fold-like subdomains
TgeneDHX36chr4:187560875chr3:154001060ENST000004968111825841_905764.01009.0RegionOB-fold-like subdomains

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4271140_12451214.04589.0DomainCadherin 10
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4271246_13571214.04589.0DomainCadherin 11
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4271359_14561214.04589.0DomainCadherin 12
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4271457_15621214.04589.0DomainCadherin 13
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4271563_16671214.04589.0DomainCadherin 14
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4271668_17651214.04589.0DomainCadherin 15
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4271766_18791214.04589.0DomainCadherin 16
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4271880_19791214.04589.0DomainCadherin 17
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4271980_20811214.04589.0DomainCadherin 18
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4272082_21821214.04589.0DomainCadherin 19
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4272183_22831214.04589.0DomainCadherin 20
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4272284_23901214.04589.0DomainCadherin 21
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4272391_24921214.04589.0DomainCadherin 22
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4272493_25961214.04589.0DomainCadherin 23
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4272597_27031214.04589.0DomainCadherin 24
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4272704_28091214.04589.0DomainCadherin 25
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4272810_29181214.04589.0DomainCadherin 26
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4272919_30231214.04589.0DomainCadherin 27
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4273024_31251214.04589.0DomainCadherin 28
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4273126_32301214.04589.0DomainCadherin 29
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4273231_33351214.04589.0DomainCadherin 30
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4273336_34401214.04589.0DomainCadherin 31
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4273441_35451214.04589.0DomainCadherin 32
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4273546_36471214.04589.0DomainCadherin 33
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4273790_38271214.04589.0DomainEGF-like 1
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4273829_40091214.04589.0DomainLaminin G-like
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4274013_40501214.04589.0DomainEGF-like 2
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4274052_40881214.04589.0DomainEGF-like 3
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4274089_41251214.04589.0DomainEGF-like 4
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4274127_41631214.04589.0DomainEGF-like 5%3B calcium-binding
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4274204_42141214.04589.0MotifNuclear localization signal
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4274378_43821214.04589.0MotifPTB-like motif
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-42722_41811214.04589.0Topological domainExtracellular
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4274203_45881214.04589.0Topological domainCytoplasmic
HgeneFAT1chr4:187560875chr3:154001060ENST00000441802-4274182_42021214.04589.0TransmembraneHelical
TgeneDHX36chr4:187560875chr3:154001060ENST00000308361172472_157735.0980.0Coiled coilOntology_term=ECO:0000255
TgeneDHX36chr4:187560875chr3:154001060ENST00000329463182572_157750.0995.0Coiled coilOntology_term=ECO:0000255
TgeneDHX36chr4:187560875chr3:154001060ENST00000496811182572_157764.01009.0Coiled coilOntology_term=ECO:0000255
TgeneDHX36chr4:187560875chr3:154001060ENST00000308361172410_63735.0980.0Compositional biasNote=Gly-rich
TgeneDHX36chr4:187560875chr3:154001060ENST00000329463182510_63750.0995.0Compositional biasNote=Gly-rich
TgeneDHX36chr4:187560875chr3:154001060ENST00000496811182510_63764.01009.0Compositional biasNote=Gly-rich
TgeneDHX36chr4:187560875chr3:154001060ENST000003083611724217_387735.0980.0DomainHelicase ATP-binding
TgeneDHX36chr4:187560875chr3:154001060ENST000003083611724477_647735.0980.0DomainHelicase C-terminal
TgeneDHX36chr4:187560875chr3:154001060ENST000003294631825217_387750.0995.0DomainHelicase ATP-binding
TgeneDHX36chr4:187560875chr3:154001060ENST000003294631825477_647750.0995.0DomainHelicase C-terminal
TgeneDHX36chr4:187560875chr3:154001060ENST000004968111825217_387764.01009.0DomainHelicase ATP-binding
TgeneDHX36chr4:187560875chr3:154001060ENST000004968111825477_647764.01009.0DomainHelicase C-terminal
TgeneDHX36chr4:187560875chr3:154001060ENST000003083611724334_337735.0980.0MotifDEAH box
TgeneDHX36chr4:187560875chr3:154001060ENST000003083611724517_528735.0980.0MotifNuclear localization signal
TgeneDHX36chr4:187560875chr3:154001060ENST000003294631825334_337750.0995.0MotifDEAH box
TgeneDHX36chr4:187560875chr3:154001060ENST000003294631825517_528750.0995.0MotifNuclear localization signal
TgeneDHX36chr4:187560875chr3:154001060ENST000004968111825334_337764.01009.0MotifDEAH box
TgeneDHX36chr4:187560875chr3:154001060ENST000004968111825517_528764.01009.0MotifNuclear localization signal
TgeneDHX36chr4:187560875chr3:154001060ENST000003083611724233_238735.0980.0Nucleotide bindingATP
TgeneDHX36chr4:187560875chr3:154001060ENST000003083611724602_605735.0980.0Nucleotide bindingATP
TgeneDHX36chr4:187560875chr3:154001060ENST000003294631825233_238750.0995.0Nucleotide bindingATP
TgeneDHX36chr4:187560875chr3:154001060ENST000003294631825602_605750.0995.0Nucleotide bindingATP
TgeneDHX36chr4:187560875chr3:154001060ENST000004968111825233_238764.01009.0Nucleotide bindingATP
TgeneDHX36chr4:187560875chr3:154001060ENST000004968111825602_605764.01009.0Nucleotide bindingATP
TgeneDHX36chr4:187560875chr3:154001060ENST000003083611724106_386735.0980.0RegionRecA-like domain 1
TgeneDHX36chr4:187560875chr3:154001060ENST0000030836117241_104735.0980.0RegionRequired for the pre-miR-134 transport
TgeneDHX36chr4:187560875chr3:154001060ENST0000030836117241_200735.0980.0RegionNecessary for nuclear and nucleolar caps localizations
TgeneDHX36chr4:187560875chr3:154001060ENST0000030836117241_51735.0980.0RegionRequired for recruitment to cytoplasmic stress granules
TgeneDHX36chr4:187560875chr3:154001060ENST000003083611724387_628735.0980.0RegionRecA-like domain 2
TgeneDHX36chr4:187560875chr3:154001060ENST00000308361172453_105735.0980.0RegionRequired for G4-DNA- and G4-RNA-binding
TgeneDHX36chr4:187560875chr3:154001060ENST00000308361172453_75735.0980.0RegionDSM (DHX36-specific motif)
TgeneDHX36chr4:187560875chr3:154001060ENST000003083611724629_698735.0980.0RegionWH domain
TgeneDHX36chr4:187560875chr3:154001060ENST000003294631825106_386750.0995.0RegionRecA-like domain 1
TgeneDHX36chr4:187560875chr3:154001060ENST0000032946318251_104750.0995.0RegionRequired for the pre-miR-134 transport
TgeneDHX36chr4:187560875chr3:154001060ENST0000032946318251_200750.0995.0RegionNecessary for nuclear and nucleolar caps localizations
TgeneDHX36chr4:187560875chr3:154001060ENST0000032946318251_51750.0995.0RegionRequired for recruitment to cytoplasmic stress granules
TgeneDHX36chr4:187560875chr3:154001060ENST000003294631825387_628750.0995.0RegionRecA-like domain 2
TgeneDHX36chr4:187560875chr3:154001060ENST00000329463182553_105750.0995.0RegionRequired for G4-DNA- and G4-RNA-binding
TgeneDHX36chr4:187560875chr3:154001060ENST00000329463182553_75750.0995.0RegionDSM (DHX36-specific motif)
TgeneDHX36chr4:187560875chr3:154001060ENST000003294631825629_698750.0995.0RegionWH domain
TgeneDHX36chr4:187560875chr3:154001060ENST000004968111825106_386764.01009.0RegionRecA-like domain 1
TgeneDHX36chr4:187560875chr3:154001060ENST0000049681118251_104764.01009.0RegionRequired for the pre-miR-134 transport
TgeneDHX36chr4:187560875chr3:154001060ENST0000049681118251_200764.01009.0RegionNecessary for nuclear and nucleolar caps localizations
TgeneDHX36chr4:187560875chr3:154001060ENST0000049681118251_51764.01009.0RegionRequired for recruitment to cytoplasmic stress granules
TgeneDHX36chr4:187560875chr3:154001060ENST000004968111825387_628764.01009.0RegionRecA-like domain 2
TgeneDHX36chr4:187560875chr3:154001060ENST00000496811182553_105764.01009.0RegionRequired for G4-DNA- and G4-RNA-binding
TgeneDHX36chr4:187560875chr3:154001060ENST00000496811182553_75764.01009.0RegionDSM (DHX36-specific motif)
TgeneDHX36chr4:187560875chr3:154001060ENST000004968111825629_698764.01009.0RegionWH domain


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Fusion Gene Sequence for FAT1-DHX36


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000441802_ENST00000496811_TCGA-CG-4301_FAT1_chr4_187560875_-_DHX36_chr3_154001060_length(transcript)=8212nt_BP=3852nt
AGCGTGAGGCGCCGGCGCCGAGCTGGGCGGCCGGGCGCGGGGAGAGGGCGCGGGAGCGGCTCGTGCGGCAGGTACCATGCGGACGCGCGA
GCCCGGCGAGGGCCCCGGCAGGCCCGGTCCCTGCTCGGGGGCGCGCTGAGACGGCGGGTGAGCTCCACGAGAGCGCCGTCGCCACTTCGG
GCCAACTTTGCGATTCCCGACAGTTAAGCAATGGGGAGACATTTGGCTTTGCTCCTGCTTCTGCTCCTTCTCTTCCAACATTTTGGAGAC
AGTGATGGCAGCCAACGACTTGAACAGACTCCTCTGCAGTTTACACACCTCGAGTACAACGTCACCGTGCAGGAGAACTCTGCAGCTAAG
ACTTATGTGGGGCATCCTGTCAAGATGGGTGTTTACATTACACATCCAGCGTGGGAAGTAAGGTACAAAATTGTTTCCGGAGACAGTGAA
AACCTGTTCAAAGCTGAAGAGTACATTCTCGGAGACTTTTGCTTTCTAAGAATAAGGACCAAAGGAGGAAATACAGCTATTCTTAATAGA
GAAGTGAAGGATCACTACACATTGATAGTGAAAGCACTTGAAAAAAATACTAATGTGGAGGCGCGAACAAAGGTCAGGGTGCAGGTGCTG
GATACAAATGACTTGAGACCGTTATTCTCACCCACCTCATACAGCGTTTCTTTACCTGAAAACACAGCTATAAGGACCAGTATCGCAAGA
GTCAGCGCCACGGATGCAGACATAGGAACCAACGGGGAATTTTACTACAGTTTTAAAGATCGAACAGATATGTTTGCTATTCACCCAACC
AGTGGTGTGATAGTGTTAACTGGTAGACTTGATTACCTAGAGACCAAGCTCTATGAGATGGAAATCCTCGCTGCGGACCGTGGCATGAAG
TTGTATGGGAGCAGTGGCATCAGCAGCATGGCCAAGCTAACGGTGCACATCGAACAGGCCAATGAATGTGCTCCGGTGATAACAGCAGTG
ACATTGTCACCATCAGAACTGGACAGGGACCCAGCATATGCAATTGTGACAGTGGATGACTGCGATCAGGGTGCCAATGGTGACATAGCA
TCTTTAAGCATCGTGGCAGGTGACCTTCTCCAGCAGTTTAGAACAGTGAGGTCCTTTCCAGGGAGTAAGGAGTATAAAGTCAAAGCCATC
GGTGGCATTGATTGGGACAGTCATCCTTTCGGCTACAATCTCACACTACAGGCTAAAGATAAAGGAACTCCGCCCCAGTTCTCTTCTGTT
AAAGTCATTCACGTGACTTCTCCACAGTTCAAAGCCGGGCCAGTCAAGTTTGAAAAGGATGTTTACAGAGCAGAAATAAGTGAATTTGCT
CCTCCCAACACACCTGTGGTCATGGTAAAGGCCATTCCTGCTTATTCCCATTTGAGGTATGTTTTTAAAAGTACACCTGGAAAAGCTAAA
TTCAGTTTAAATTACAACACTGGTCTCATTTCTATTTTAGAACCAGTTAAAAGACAGCAGGCAGCCCATTTTGAACTTGAAGTAACAACA
AGTGACAGAAAAGCGTCCACCAAGGTCTTGGTGAAAGTCTTAGGTGCAAATAGCAATCCCCCTGAATTTACCCAGACAGCGTACAAAGCT
GCTTTTGATGAGAACGTGCCCATTGGTACTACTGTCATGAGCCTGAGTGCCGTAGACCCTGATGAGGGTGAGAACGGGTACGTGACATAC
AGTATCGCAAATTTAAATCATGTGCCGTTTGCGATTGACCATTTCACTGGTGCCGTGAGTACGTCAGAAAACCTGGACTACGAACTGATG
CCTCGGGTTTATACTCTGAGGATTCGTGCATCAGACTGGGGCTTGCCGTACCGCCGGGAAGTCGAAGTCCTTGCTACAATTACTCTCAAT
AACTTGAATGACAACACACCTTTGTTTGAGAAAATAAATTGTGAAGGGACAATTCCCAGAGATCTAGGCGTGGGAGAGCAAATAACCACT
GTTTCTGCTATTGATGCAGATGAACTTCAGTTGGTACAGTATCAGATTGAAGCTGGAAATGAACTGGATTTCTTTAGTTTAAACCCCAAC
TCGGGGGTATTGTCATTAAAGCGATCGCTAATGGATGGCTTAGGTGCAAAGGTGTCTTTCCACAGTCTGAGAATCACAGCTACAGATGGA
GAAAATTTTGCCACACCATTATATATCAACATAACAGTGGCTGCCAGTCACAAGCTGGTAAACTTGCAGTGTGAAGAGACTGGTGTTGCC
AAAATGCTGGCAGAGAAGCTCCTGCAGGCAAATAAATTACACAACCAGGGAGAGGTGGAGGATATTTTCTTCGATTCTCACTCTGTCAAT
GCTCACATACCGCAGTTTAGAAGCACTCTTCCGACTGGTATTCAGGTAAAGGAAAACCAGCCTGTGGGTTCCAGTGTAATTTTCATGAAC
TCCACTGACCTTGACACTGGCTTCAATGGAAAACTGGTCTATGCTGTTTCTGGAGGAAATGAGGATAGTTGCTTCATGATTGATATGGAA
ACAGGAATGCTGAAAATTTTATCTCCTCTTGACCGTGAAACAACAGACAAATACACCCTGAATATTACCGTCTATGACCTTGGGATACCC
CAGAAGGCTGCGTGGCGTCTTCTACATGTCGTGGTTGTCGATGCCAATGATAATCCACCCGAGTTTTTACAGGAGAGCTATTTTGTGGAA
GTGAGTGAAGACAAGGAGGTACATAGTGAAATCATCCAGGTTGAAGCCACAGATAAAGACCTGGGGCCCAACGGACACGTGACGTACTCA
ATTGTTACAGACACAGACACATTTTCAATTGACAGCGTGACGGGTGTTGTTAACATCGCACGCCCTCTGGATCGAGAGCTGCAGCATGAG
CACTCCTTAAAGATTGAGGCCAGGGACCAAGCCAGAGAAGAGCCTCAGCTGTTCTCCACTGTCGTTGTGAAAGTATCACTAGAAGATGTT
AATGACAACCCACCTACATTTATTCCACCTAATTATCGTGTGAAAGTCCGAGAGGATCTTCCAGAAGGAACCGTCATCATGTGGTTAGAA
GCCCACGATCCTGATTTAGGTCAGTCTGGTCAGGTGAGATACAGCCTTCTGGACCACGGAGAAGGAAACTTCGATGTGGATAAACTCAGT
GGAGCAGTTAGGATCGTCCAGCAGTTGGACTTTGAGAAGAAGCAAGTGTATAATCTCACTGTGAGGGCCAAAGACAAGGGAAAGCCAGTT
TCTCTGTCTTCTACTTGCTATGTTGAAGTTGAGGTGGTTGATGTGAATGAGAACCTGCACCCACCCGTGTTTTCCAGCTTTGTGGAAAAG
GGGACAGTGAAAGAAGATGCACCTGTTGGTTCATTGGTAATGACGGTGTCGGCTCATGATGAGGACGCCAGAAGAGATGGGGAGATCCGA
TACTCCATTAGAGATGGCTCTGGCGTTGGTGTTTTCAAAATAGGTGAAGAGACAGGTGTCATAGAGACGTCAGATCGACTGGACCGTGAA
TCGACCTCCCATTATTGGCTAACAGTCTTTGCAACCGATCAGGGTGTCGTGCCTCTTTCATCGTTCATAGAGATCTACATAGAGGTTGAG
GATGTCAATGACAATGCACCACAGACATCAGAGCCTGTTTATTACCCAGAAATCATGGAAAATTCTCCTAAAGATGTATCTGTGGTCCAG
ATCGAGGCATTTGATCCAGATTCGAGCTCTAATGACAAGCTCATGTACAAAATTACAAGTGGAAATCCACAAGGATTCTTTTCAATACAT
CCTAAAACAGGTCTCATCACAACTACGTCAAGGAAGCTAGACCGAGAACAGCAAGATGAACACATATTAGAGGGCTGGGAAGAGGCTAGG
CGACGTGGTTTCAGATACGAAAAGGACTATTGCTGGGAATATTTTCTGTCTTCAAACACACTGCAGATGCTGCATAACATGAAAGGACAG
TTTGCTGAGCATCTTCTTGGAGCTGGATTTGTAAGCAGTAGAAATCCTAAAGATCCAGAATCTAATATAAATTCAGATAATGAGAAGATA
ATTAAAGCTGTCATCTGTGCTGGTTTATATCCCAAAGTTGCTAAAATTCGACTAAATTTGGGTAAAAAAAGAAAAATGGTAAAAGTTTAC
ACAAAAACCGATGGCCTGGTTGCTGTTCATCCTAAATCTGTTAATGTGGAGCAAACAGACTTTCACTACAACTGGCTTATCTATCACCTA
AAGATGAGAACAAGCAGTATATACTTGTATGACTGCACAGAGGTTTCCCCATACTGTCTCTTGTTTTTTGGAGGTGACATTTCCATCCAG
AAGGATAACGATCAGGAAACTATTGCTGTAGATGAGTGGATTGTATTTCAGTCTCCAGCAAGAATTGCCCATCTTGTTAAGGAATTAAGA
AAGGAACTAGATATTCTTCTGCAAGAGAAGATTGAAAGTCCTCATCCTGTAGACTGGAATGACACTAAATCCAGAGACTGTGCAGTACTG
TCAGCTATTATAGACTTGATCAAAACACAGGAAAAGGCAACTCCCAGGAACTTTCCGCCACGATTCCAGGATGGATATTACAGCTGACAG
CTTTTCAGGGGTGGTCTGAAAAGCCAGTTTGACAGCCATTCTTCATCATTGTTTAAATTTTGGCTGGATGCCAAACCCTGGGACATGAAC
AATTTTCATGTGTAAGGTAGAAGCCTTCAGTAGGTAGTAAAGACTTAATGTGCATGACTTGATGTTATATGTAGAGATATATATATATAT
ATATATATACCATAAAAGCAATATGTTCTCTGATCATATACTCTGCTGTGGTCATGCCCACTCTTTGGGAGTATATTCCCTTTATATATA
TTGAGTATTGTACCACTTGAGAAATTCCTTTGTTCTGTTATACAAAATTAATCTTTCTGCTCATAATGATTGATGATACCACCAGTAAAA
ATAGGATGTTTACCCCAAAACAAGTGTCAATTAAGAATTTGAACACAACCACATTTTTTAAAATGAAACTTCTATCGGAAGTAAATTAAT
TTGTTGTAATAAAGTCCAGTATTTAATAAAATGTACAATGTTAAATCTCAGCCAACCTCTTGGATTGGTTTCTACATTTTCACCTATGGC
TTGGTTCATTTGATATTTTTACTATTTTTAAAACACGTGCCCTTTTTATATCACCCTGTGCCTCATAATACAGCAATTGAGAGCACGGTC
TGGAGCCTGATTACCTCAGTTCCAGTCTCAGCTCTGTCAGTTAGTCAGTGTCTTGGCTTCTCTCCTTTTTCCTTATCTTGTAAGATACAG
TTGGCCCTTCATATCCATGCATTCCACATCTGTGGATTCAAACAACTGTGGATAGAAGATATTTGGGGAAAAAAAGGATGGTTGTGTCTA
TACTGAACATGTGCAGACTTTTTTCCTTGTCATTCCCTAAACAATACAGTTTAACAGCTATTTATATAGTATTTACATTGTATTAGGTAT
TATAAATAATCTAGAGATGACTTAAAGAATATGGGAGGTTGTGCCTAGGTAACATGCAAATACTACGCCATTTTATTATAAAAGACTTGA
GCATCCATGGATTTAGGTATTTGAGGGGTTGGGGTTGGAAACCAGTCCCCCACAGATACTGAGGGACAACTGTACATGTAACAGTTGTGA
GGATGAAGTACATTAATACATGTAAAGCACATAGGCTAGTGCCTGTACTCTCTGAATCTTAGTTGTTATTTGTCCCTGAAATATTTTCGT
AAATGTCTAACAATCTATTATATTACACTTTTTATTTTATTGCTACTTATCTTCTTCGCCAAGGAATAGTGTAACAACACATGCTGTACA
TTTTCAGCCCTATCAGATTGTGATAAATACTGTTGGTTGCCGGCCAGCAACTATTTTGTCCCTCCCTTCTTGCTTGCTTATTCTGGTGTT
CCCTTCTGTGCAGCTCTGTGTCCAGGTATGTTGGACCCTTTCCCTAAGGGTGAATCCTGCTGTTCTAAATGAATCACATGTGGTCTTATC
CCCCTTATAAGTAATTGATAAGGCATGAGTACATAAACATGTCCTAGTGAATGGCAGCTGAGAAGTGATCTTCAAGGGGGTGTCTGAAAA
ATGTTTTACTCACTAATAGGCTTAGAGGAGGAAATCCTGCTCTCTCTGGACATTGTCTTTTCTGACTCTGATAGTTGGAACTGCTGCAGC
CAACTAATGATCACAAGGAGACACGGACTCAGACTGAGGTTAGCTCAGTGGAAAGATAGAACTCACCAGAGCCTTTGATAATGCCGGTAA
GCTTCAGAATTAACCCATTCTAGAGCTGCTTTACATGTGGACTTATGTTGATATAATAAAAACCCTTCAATTGTTTAAGCCACTTTTAAT
AGGATATTGTTAGTTTTTTGTTGGTTTTTTGTTTTGTTTTGTTTTGTTTTTTGTTTTTTGGAGACAGTGTCTTGCCCTGTCACCCAGGCT
GGAGTGCAGTGGTGTGATCTTGGTTCACTGCAGCCTCGACTTCCTGGGTTCAAGTGATCCTTCTGCCTCAGCCTCCCAAATAGCTGGGAC
TATAGGCATGCATCACCACACCCAGCTAATTTCTGTATTTTTTGTAGAGACACCGTTTCACCATGTTGCCCAGGCTGGTCTCAAAACTCC
TGTGCTCAAGCAGTCTGCCCGCCTTGGCTTCCCAAAGTGCTGACATTACAGGTATGAGCCACTGCACCCGGTCCCTAGTAGGGTATTTTT
AACTTGGCAAAAAGGGTATTAATCAGAAACATACACTATCCATCACTGAGTATTATACTCTTGATTTTGCAATGTAAGAGTTTTAACCTA
TTTGTCTGACAGAAGGTGTAAAAGTGCTGGACATGCTGCAGAAAGAAACAGGAAAAGCATCTTGCTGCACTCCAAAGAATGCAAATTTTA
ATGTGCCTTCCAATAAATGCAAGGAAACCGAAAGAGTTAATAGTATCATACAATGACTGGGATGTATTGATAATGCTACAGTGATCCATT
AACAGCACTTGTTCAGGTACTGCTCCCAATCCTGGGAATGTGTGTTACCTGTTATGTCTCAAATCCTTTATCTTGGCTGTTCTTCTAAAA
GTGATCTGTCTGTCATTGAATGCTGGCATTAGAGTCATGTCACAATATTAGAGCATACTGGTTTTGCCTCTAACGTCGAGGTGACCATCT
GGTCTTTCTTGCTCTGTAAGAGTTTCTGTTTGTGCTTTTTTTTCCCTTACTTTTATTATCCAGTTTAAATCCAGTCAGTTGGCCAAAATG
GTCTTGGAAGAAAGGATTTAGAGATTCTGTAAAAAAGATTATTAGTTGGTTCTGTGTTTGCAAACCAGTATGTAATTCCCATATGAATGG
GGAAAATGTTCCTGAGGAATTATTTAATTGATGAGGCATTCACAGAGATTAAAGCAGTTATTGTTACCTCCAATTTATGTCTTCTGCACA
GCTGATTAGGTTGGACATTTTAATCCAAGGTGCTACTTACATTCTGTTTCTTTTGTTTACAAAATAGGGCATTACTGAGTAGAAAATACA
TTCCAGGTCTAAGAACTGTTTGTTCTTTAGTGGATTTTAAAGAATAAGACATTAAATTAAGAAGGAAAATCTGTTTGATTCATCATTTTG
AGTAATGCAGAGAATAACTCTTAAAAAAAAAACCTGAAACAGAAACTTTCAGGAAAAAAACAAAAGAAATTAAACTACTGAATAATCTTT
CAAAAGCATCGTTGAACAGTGAGCACATGTGATGCCTTCCCAATTAATTAATTTGGGCAAAAGCTCTAGATAAACTTACACCAATTGTTG
CAAGGCATTCTCTATTACTGCATTTTTAAAACAAAGTCCTCCCCTAAAAGTTATGAATTATACAAAAGCTTTAGGAGGAATTTTAGTACT
CCTTTACCCAAAATAAATAGTGGTAAATTTCCTTCTGTTCTTAGCTCTGAGTTTGTATTTATTTATAAGTCATTGTGATCATGTATACTT
ATATATTTTTAATATGCTAATTGCTTTTAAATGGGATTTTTGTTCTGATTTTAAAATAATACATCCTCCCTGGACAATATTTGGAAATGT
AGCAAAGTAAATCATGTTACCATTGTTCCATTTTGATATATATAAACTTTAGGTATTATTTTATATATAATAAATTTTAAGATATTATAT

>In-frame_ENST00000441802_ENST00000496811_TCGA-CG-4301_FAT1_chr4_187560875_-_DHX36_chr3_154001060_length(amino acids)=1458AA_start in transcript=210_stop in transcript=4586
MGRHLALLLLLLLLFQHFGDSDGSQRLEQTPLQFTHLEYNVTVQENSAAKTYVGHPVKMGVYITHPAWEVRYKIVSGDSENLFKAEEYIL
GDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEKNTNVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGT
NGEFYYSFKDRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRD
PAYAIVTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVTSPQF
KAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPAYSHLRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDRKASTKVL
VKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSIANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRA
SDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELDFFSLNPNSGVLSLKRSL
MDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTL
PTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQKAAWRLLHV
VVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTDTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQ
AREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSGAVRIVQQLD
FEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVG
VFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSS
NDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGF
VSSRNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY
DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQ

--------------------------------------------------------------
>In-frame_ENST00000441802_ENST00000308361_TCGA-CG-4301_FAT1_chr4_187560875_-_DHX36_chr3_154001060_length(transcript)=5090nt_BP=3852nt
AGCGTGAGGCGCCGGCGCCGAGCTGGGCGGCCGGGCGCGGGGAGAGGGCGCGGGAGCGGCTCGTGCGGCAGGTACCATGCGGACGCGCGA
GCCCGGCGAGGGCCCCGGCAGGCCCGGTCCCTGCTCGGGGGCGCGCTGAGACGGCGGGTGAGCTCCACGAGAGCGCCGTCGCCACTTCGG
GCCAACTTTGCGATTCCCGACAGTTAAGCAATGGGGAGACATTTGGCTTTGCTCCTGCTTCTGCTCCTTCTCTTCCAACATTTTGGAGAC
AGTGATGGCAGCCAACGACTTGAACAGACTCCTCTGCAGTTTACACACCTCGAGTACAACGTCACCGTGCAGGAGAACTCTGCAGCTAAG
ACTTATGTGGGGCATCCTGTCAAGATGGGTGTTTACATTACACATCCAGCGTGGGAAGTAAGGTACAAAATTGTTTCCGGAGACAGTGAA
AACCTGTTCAAAGCTGAAGAGTACATTCTCGGAGACTTTTGCTTTCTAAGAATAAGGACCAAAGGAGGAAATACAGCTATTCTTAATAGA
GAAGTGAAGGATCACTACACATTGATAGTGAAAGCACTTGAAAAAAATACTAATGTGGAGGCGCGAACAAAGGTCAGGGTGCAGGTGCTG
GATACAAATGACTTGAGACCGTTATTCTCACCCACCTCATACAGCGTTTCTTTACCTGAAAACACAGCTATAAGGACCAGTATCGCAAGA
GTCAGCGCCACGGATGCAGACATAGGAACCAACGGGGAATTTTACTACAGTTTTAAAGATCGAACAGATATGTTTGCTATTCACCCAACC
AGTGGTGTGATAGTGTTAACTGGTAGACTTGATTACCTAGAGACCAAGCTCTATGAGATGGAAATCCTCGCTGCGGACCGTGGCATGAAG
TTGTATGGGAGCAGTGGCATCAGCAGCATGGCCAAGCTAACGGTGCACATCGAACAGGCCAATGAATGTGCTCCGGTGATAACAGCAGTG
ACATTGTCACCATCAGAACTGGACAGGGACCCAGCATATGCAATTGTGACAGTGGATGACTGCGATCAGGGTGCCAATGGTGACATAGCA
TCTTTAAGCATCGTGGCAGGTGACCTTCTCCAGCAGTTTAGAACAGTGAGGTCCTTTCCAGGGAGTAAGGAGTATAAAGTCAAAGCCATC
GGTGGCATTGATTGGGACAGTCATCCTTTCGGCTACAATCTCACACTACAGGCTAAAGATAAAGGAACTCCGCCCCAGTTCTCTTCTGTT
AAAGTCATTCACGTGACTTCTCCACAGTTCAAAGCCGGGCCAGTCAAGTTTGAAAAGGATGTTTACAGAGCAGAAATAAGTGAATTTGCT
CCTCCCAACACACCTGTGGTCATGGTAAAGGCCATTCCTGCTTATTCCCATTTGAGGTATGTTTTTAAAAGTACACCTGGAAAAGCTAAA
TTCAGTTTAAATTACAACACTGGTCTCATTTCTATTTTAGAACCAGTTAAAAGACAGCAGGCAGCCCATTTTGAACTTGAAGTAACAACA
AGTGACAGAAAAGCGTCCACCAAGGTCTTGGTGAAAGTCTTAGGTGCAAATAGCAATCCCCCTGAATTTACCCAGACAGCGTACAAAGCT
GCTTTTGATGAGAACGTGCCCATTGGTACTACTGTCATGAGCCTGAGTGCCGTAGACCCTGATGAGGGTGAGAACGGGTACGTGACATAC
AGTATCGCAAATTTAAATCATGTGCCGTTTGCGATTGACCATTTCACTGGTGCCGTGAGTACGTCAGAAAACCTGGACTACGAACTGATG
CCTCGGGTTTATACTCTGAGGATTCGTGCATCAGACTGGGGCTTGCCGTACCGCCGGGAAGTCGAAGTCCTTGCTACAATTACTCTCAAT
AACTTGAATGACAACACACCTTTGTTTGAGAAAATAAATTGTGAAGGGACAATTCCCAGAGATCTAGGCGTGGGAGAGCAAATAACCACT
GTTTCTGCTATTGATGCAGATGAACTTCAGTTGGTACAGTATCAGATTGAAGCTGGAAATGAACTGGATTTCTTTAGTTTAAACCCCAAC
TCGGGGGTATTGTCATTAAAGCGATCGCTAATGGATGGCTTAGGTGCAAAGGTGTCTTTCCACAGTCTGAGAATCACAGCTACAGATGGA
GAAAATTTTGCCACACCATTATATATCAACATAACAGTGGCTGCCAGTCACAAGCTGGTAAACTTGCAGTGTGAAGAGACTGGTGTTGCC
AAAATGCTGGCAGAGAAGCTCCTGCAGGCAAATAAATTACACAACCAGGGAGAGGTGGAGGATATTTTCTTCGATTCTCACTCTGTCAAT
GCTCACATACCGCAGTTTAGAAGCACTCTTCCGACTGGTATTCAGGTAAAGGAAAACCAGCCTGTGGGTTCCAGTGTAATTTTCATGAAC
TCCACTGACCTTGACACTGGCTTCAATGGAAAACTGGTCTATGCTGTTTCTGGAGGAAATGAGGATAGTTGCTTCATGATTGATATGGAA
ACAGGAATGCTGAAAATTTTATCTCCTCTTGACCGTGAAACAACAGACAAATACACCCTGAATATTACCGTCTATGACCTTGGGATACCC
CAGAAGGCTGCGTGGCGTCTTCTACATGTCGTGGTTGTCGATGCCAATGATAATCCACCCGAGTTTTTACAGGAGAGCTATTTTGTGGAA
GTGAGTGAAGACAAGGAGGTACATAGTGAAATCATCCAGGTTGAAGCCACAGATAAAGACCTGGGGCCCAACGGACACGTGACGTACTCA
ATTGTTACAGACACAGACACATTTTCAATTGACAGCGTGACGGGTGTTGTTAACATCGCACGCCCTCTGGATCGAGAGCTGCAGCATGAG
CACTCCTTAAAGATTGAGGCCAGGGACCAAGCCAGAGAAGAGCCTCAGCTGTTCTCCACTGTCGTTGTGAAAGTATCACTAGAAGATGTT
AATGACAACCCACCTACATTTATTCCACCTAATTATCGTGTGAAAGTCCGAGAGGATCTTCCAGAAGGAACCGTCATCATGTGGTTAGAA
GCCCACGATCCTGATTTAGGTCAGTCTGGTCAGGTGAGATACAGCCTTCTGGACCACGGAGAAGGAAACTTCGATGTGGATAAACTCAGT
GGAGCAGTTAGGATCGTCCAGCAGTTGGACTTTGAGAAGAAGCAAGTGTATAATCTCACTGTGAGGGCCAAAGACAAGGGAAAGCCAGTT
TCTCTGTCTTCTACTTGCTATGTTGAAGTTGAGGTGGTTGATGTGAATGAGAACCTGCACCCACCCGTGTTTTCCAGCTTTGTGGAAAAG
GGGACAGTGAAAGAAGATGCACCTGTTGGTTCATTGGTAATGACGGTGTCGGCTCATGATGAGGACGCCAGAAGAGATGGGGAGATCCGA
TACTCCATTAGAGATGGCTCTGGCGTTGGTGTTTTCAAAATAGGTGAAGAGACAGGTGTCATAGAGACGTCAGATCGACTGGACCGTGAA
TCGACCTCCCATTATTGGCTAACAGTCTTTGCAACCGATCAGGGTGTCGTGCCTCTTTCATCGTTCATAGAGATCTACATAGAGGTTGAG
GATGTCAATGACAATGCACCACAGACATCAGAGCCTGTTTATTACCCAGAAATCATGGAAAATTCTCCTAAAGATGTATCTGTGGTCCAG
ATCGAGGCATTTGATCCAGATTCGAGCTCTAATGACAAGCTCATGTACAAAATTACAAGTGGAAATCCACAAGGATTCTTTTCAATACAT
CCTAAAACAGGTCTCATCACAACTACGTCAAGGAAGCTAGACCGAGAACAGCAAGATGAACACATATTAGAGGGCTGGGAAGAGGCTAGG
CGACGTGGTTTCAGATACGAAAAGGACTATTGCTGGGAATATTTTCTGTCTTCAAACACACTGCAGATGCTGCATAACATGAAAGGACAG
TTTGCTGAGCATCTTCTTGGAGCTGGATTTGTAAGCAGTAGAAATCCTAAAGATCCAGAATCTAATATAAATTCAGATAATGAGAAGATA
ATTAAAGCTGTCATCTGTGCTGGTTTATATCCCAAAGTTGCTAAAATTCGACTAAATTTGGGTAAAAAAAGAAAAATGGTAAAAGTTTAC
ACAAAAACCGATGGCCTGGTTGCTGTTCATCCTAAATCTGTTAATGTGGAGCAAACAGACTTTCACTACAACTGGCTTATCTATCACCTA
AAGATGAGAACAAGCAGTATATACTTGTATGACTGCACAGAGGTTTCCCCATACTGTCTCTTGTTTTTTGGAGGTGACATTTCCATCCAG
AAGGATAACGATCAGGAAACTATTGCTGTAGATGAGTGGATTGTATTTCAGTCTCCAGCAAGAATTGCCCATCTTGTTAAGGAATTAAGA
AAGGAACTAGATATTCTTCTGCAAGAGAAGATTGAAAGTCCTCATCCTGTAGACTGGAATGACACTAAATCCAGAGACTGTGCAGTACTG
TCAGCTATTATAGACTTGATCAAAACACAGGAAAAGGCAACTCCCAGGAACTTTCCGCCACGATTCCAGGATGGATATTACAGCTGACAG
CTTTTCAGGGGTGGTCTGAAAAGCCAGTTTGACAGCCATTCTTCATCATTGTTTAAATTTTGGCTGGATGCCAAACCCTGGGACATGAAC
AATTTTCATGTGTAAGGTAGAAGCCTTCAGTAGGTAGTAAAGACTTAATGTGCATGACTTGATGTTATATGTAGAGATATATATATATAT
ATATATATACCATAAAAGCAATATGTTCTCTGATCATATACTCTGCTGTGGTCATGCCCACTCTTTGGGAGTATATTCCCTTTATATATA
TTGAGTATTGTACCACTTGAGAAATTCCTTTGTTCTGTTATACAAAATTAATCTTTCTGCTCATAATGATTGATGATACCACCAGTAAAA
ATAGGATGTTTACCCCAAAACAAGTGTCAATTAAGAATTTGAACACAACCACATTTTTTAAAATGAAACTTCTATCGGAAGTAAATTAAT

>In-frame_ENST00000441802_ENST00000308361_TCGA-CG-4301_FAT1_chr4_187560875_-_DHX36_chr3_154001060_length(amino acids)=1458AA_start in transcript=210_stop in transcript=4586
MGRHLALLLLLLLLFQHFGDSDGSQRLEQTPLQFTHLEYNVTVQENSAAKTYVGHPVKMGVYITHPAWEVRYKIVSGDSENLFKAEEYIL
GDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEKNTNVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGT
NGEFYYSFKDRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRD
PAYAIVTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVTSPQF
KAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPAYSHLRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDRKASTKVL
VKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSIANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRA
SDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELDFFSLNPNSGVLSLKRSL
MDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTL
PTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQKAAWRLLHV
VVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTDTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQ
AREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSGAVRIVQQLD
FEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVG
VFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSS
NDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGF
VSSRNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY
DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQ

--------------------------------------------------------------
>In-frame_ENST00000441802_ENST00000544526_TCGA-CG-4301_FAT1_chr4_187560875_-_DHX36_chr3_154001060_length(transcript)=5089nt_BP=3852nt
AGCGTGAGGCGCCGGCGCCGAGCTGGGCGGCCGGGCGCGGGGAGAGGGCGCGGGAGCGGCTCGTGCGGCAGGTACCATGCGGACGCGCGA
GCCCGGCGAGGGCCCCGGCAGGCCCGGTCCCTGCTCGGGGGCGCGCTGAGACGGCGGGTGAGCTCCACGAGAGCGCCGTCGCCACTTCGG
GCCAACTTTGCGATTCCCGACAGTTAAGCAATGGGGAGACATTTGGCTTTGCTCCTGCTTCTGCTCCTTCTCTTCCAACATTTTGGAGAC
AGTGATGGCAGCCAACGACTTGAACAGACTCCTCTGCAGTTTACACACCTCGAGTACAACGTCACCGTGCAGGAGAACTCTGCAGCTAAG
ACTTATGTGGGGCATCCTGTCAAGATGGGTGTTTACATTACACATCCAGCGTGGGAAGTAAGGTACAAAATTGTTTCCGGAGACAGTGAA
AACCTGTTCAAAGCTGAAGAGTACATTCTCGGAGACTTTTGCTTTCTAAGAATAAGGACCAAAGGAGGAAATACAGCTATTCTTAATAGA
GAAGTGAAGGATCACTACACATTGATAGTGAAAGCACTTGAAAAAAATACTAATGTGGAGGCGCGAACAAAGGTCAGGGTGCAGGTGCTG
GATACAAATGACTTGAGACCGTTATTCTCACCCACCTCATACAGCGTTTCTTTACCTGAAAACACAGCTATAAGGACCAGTATCGCAAGA
GTCAGCGCCACGGATGCAGACATAGGAACCAACGGGGAATTTTACTACAGTTTTAAAGATCGAACAGATATGTTTGCTATTCACCCAACC
AGTGGTGTGATAGTGTTAACTGGTAGACTTGATTACCTAGAGACCAAGCTCTATGAGATGGAAATCCTCGCTGCGGACCGTGGCATGAAG
TTGTATGGGAGCAGTGGCATCAGCAGCATGGCCAAGCTAACGGTGCACATCGAACAGGCCAATGAATGTGCTCCGGTGATAACAGCAGTG
ACATTGTCACCATCAGAACTGGACAGGGACCCAGCATATGCAATTGTGACAGTGGATGACTGCGATCAGGGTGCCAATGGTGACATAGCA
TCTTTAAGCATCGTGGCAGGTGACCTTCTCCAGCAGTTTAGAACAGTGAGGTCCTTTCCAGGGAGTAAGGAGTATAAAGTCAAAGCCATC
GGTGGCATTGATTGGGACAGTCATCCTTTCGGCTACAATCTCACACTACAGGCTAAAGATAAAGGAACTCCGCCCCAGTTCTCTTCTGTT
AAAGTCATTCACGTGACTTCTCCACAGTTCAAAGCCGGGCCAGTCAAGTTTGAAAAGGATGTTTACAGAGCAGAAATAAGTGAATTTGCT
CCTCCCAACACACCTGTGGTCATGGTAAAGGCCATTCCTGCTTATTCCCATTTGAGGTATGTTTTTAAAAGTACACCTGGAAAAGCTAAA
TTCAGTTTAAATTACAACACTGGTCTCATTTCTATTTTAGAACCAGTTAAAAGACAGCAGGCAGCCCATTTTGAACTTGAAGTAACAACA
AGTGACAGAAAAGCGTCCACCAAGGTCTTGGTGAAAGTCTTAGGTGCAAATAGCAATCCCCCTGAATTTACCCAGACAGCGTACAAAGCT
GCTTTTGATGAGAACGTGCCCATTGGTACTACTGTCATGAGCCTGAGTGCCGTAGACCCTGATGAGGGTGAGAACGGGTACGTGACATAC
AGTATCGCAAATTTAAATCATGTGCCGTTTGCGATTGACCATTTCACTGGTGCCGTGAGTACGTCAGAAAACCTGGACTACGAACTGATG
CCTCGGGTTTATACTCTGAGGATTCGTGCATCAGACTGGGGCTTGCCGTACCGCCGGGAAGTCGAAGTCCTTGCTACAATTACTCTCAAT
AACTTGAATGACAACACACCTTTGTTTGAGAAAATAAATTGTGAAGGGACAATTCCCAGAGATCTAGGCGTGGGAGAGCAAATAACCACT
GTTTCTGCTATTGATGCAGATGAACTTCAGTTGGTACAGTATCAGATTGAAGCTGGAAATGAACTGGATTTCTTTAGTTTAAACCCCAAC
TCGGGGGTATTGTCATTAAAGCGATCGCTAATGGATGGCTTAGGTGCAAAGGTGTCTTTCCACAGTCTGAGAATCACAGCTACAGATGGA
GAAAATTTTGCCACACCATTATATATCAACATAACAGTGGCTGCCAGTCACAAGCTGGTAAACTTGCAGTGTGAAGAGACTGGTGTTGCC
AAAATGCTGGCAGAGAAGCTCCTGCAGGCAAATAAATTACACAACCAGGGAGAGGTGGAGGATATTTTCTTCGATTCTCACTCTGTCAAT
GCTCACATACCGCAGTTTAGAAGCACTCTTCCGACTGGTATTCAGGTAAAGGAAAACCAGCCTGTGGGTTCCAGTGTAATTTTCATGAAC
TCCACTGACCTTGACACTGGCTTCAATGGAAAACTGGTCTATGCTGTTTCTGGAGGAAATGAGGATAGTTGCTTCATGATTGATATGGAA
ACAGGAATGCTGAAAATTTTATCTCCTCTTGACCGTGAAACAACAGACAAATACACCCTGAATATTACCGTCTATGACCTTGGGATACCC
CAGAAGGCTGCGTGGCGTCTTCTACATGTCGTGGTTGTCGATGCCAATGATAATCCACCCGAGTTTTTACAGGAGAGCTATTTTGTGGAA
GTGAGTGAAGACAAGGAGGTACATAGTGAAATCATCCAGGTTGAAGCCACAGATAAAGACCTGGGGCCCAACGGACACGTGACGTACTCA
ATTGTTACAGACACAGACACATTTTCAATTGACAGCGTGACGGGTGTTGTTAACATCGCACGCCCTCTGGATCGAGAGCTGCAGCATGAG
CACTCCTTAAAGATTGAGGCCAGGGACCAAGCCAGAGAAGAGCCTCAGCTGTTCTCCACTGTCGTTGTGAAAGTATCACTAGAAGATGTT
AATGACAACCCACCTACATTTATTCCACCTAATTATCGTGTGAAAGTCCGAGAGGATCTTCCAGAAGGAACCGTCATCATGTGGTTAGAA
GCCCACGATCCTGATTTAGGTCAGTCTGGTCAGGTGAGATACAGCCTTCTGGACCACGGAGAAGGAAACTTCGATGTGGATAAACTCAGT
GGAGCAGTTAGGATCGTCCAGCAGTTGGACTTTGAGAAGAAGCAAGTGTATAATCTCACTGTGAGGGCCAAAGACAAGGGAAAGCCAGTT
TCTCTGTCTTCTACTTGCTATGTTGAAGTTGAGGTGGTTGATGTGAATGAGAACCTGCACCCACCCGTGTTTTCCAGCTTTGTGGAAAAG
GGGACAGTGAAAGAAGATGCACCTGTTGGTTCATTGGTAATGACGGTGTCGGCTCATGATGAGGACGCCAGAAGAGATGGGGAGATCCGA
TACTCCATTAGAGATGGCTCTGGCGTTGGTGTTTTCAAAATAGGTGAAGAGACAGGTGTCATAGAGACGTCAGATCGACTGGACCGTGAA
TCGACCTCCCATTATTGGCTAACAGTCTTTGCAACCGATCAGGGTGTCGTGCCTCTTTCATCGTTCATAGAGATCTACATAGAGGTTGAG
GATGTCAATGACAATGCACCACAGACATCAGAGCCTGTTTATTACCCAGAAATCATGGAAAATTCTCCTAAAGATGTATCTGTGGTCCAG
ATCGAGGCATTTGATCCAGATTCGAGCTCTAATGACAAGCTCATGTACAAAATTACAAGTGGAAATCCACAAGGATTCTTTTCAATACAT
CCTAAAACAGGTCTCATCACAACTACGTCAAGGAAGCTAGACCGAGAACAGCAAGATGAACACATATTAGAGGGCTGGGAAGAGGCTAGG
CGACGTGGTTTCAGATACGAAAAGGACTATTGCTGGGAATATTTTCTGTCTTCAAACACACTGCAGATGCTGCATAACATGAAAGGACAG
TTTGCTGAGCATCTTCTTGGAGCTGGATTTGTAAGCAGTAGAAATCCTAAAGATCCAGAATCTAATATAAATTCAGATAATGAGAAGATA
ATTAAAGCTGTCATCTGTGCTGGTTTATATCCCAAAGTTGCTAAAATTCGACTAAATTTGGGTAAAAAAAGAAAAATGGTAAAAGTTTAC
ACAAAAACCGATGGCCTGGTTGCTGTTCATCCTAAATCTGTTAATGTGGAGCAAACAGACTTTCACTACAACTGGCTTATCTATCACCTA
AAGATGAGAACAAGCAGTATATACTTGTATGACTGCACAGAGGTTTCCCCATACTGTCTCTTGTTTTTTGGAGGTGACATTTCCATCCAG
AAGGATAACGATCAGGAAACTATTGCTGTAGATGAGTGGATTGTATTTCAGTCTCCAGCAAGAATTGCCCATCTTGTTAAGGAATTAAGA
AAGGAACTAGATATTCTTCTGCAAGAGAAGATTGAAAGTCCTCATCCTGTAGACTGGAATGACACTAAATCCAGAGACTGTGCAGTACTG
TCAGCTATTATAGACTTGATCAAAACACAGGAAAAGGCAACTCCCAGGAACTTTCCGCCACGATTCCAGGATGGATATTACAGCTGACAG
CTTTTCAGGGGTGGTCTGAAAAGCCAGTTTGACAGCCATTCTTCATCATTGTTTAAATTTTGGCTGGATGCCAAACCCTGGGACATGAAC
AATTTTCATGTGTAAGGTAGAAGCCTTCAGTAGGTAGTAAAGACTTAATGTGCATGACTTGATGTTATATGTAGAGATATATATATATAT
ATATATATACCATAAAAGCAATATGTTCTCTGATCATATACTCTGCTGTGGTCATGCCCACTCTTTGGGAGTATATTCCCTTTATATATA
TTGAGTATTGTACCACTTGAGAAATTCCTTTGTTCTGTTATACAAAATTAATCTTTCTGCTCATAATGATTGATGATACCACCAGTAAAA
ATAGGATGTTTACCCCAAAACAAGTGTCAATTAAGAATTTGAACACAACCACATTTTTTAAAATGAAACTTCTATCGGAAGTAAATTAAT

>In-frame_ENST00000441802_ENST00000544526_TCGA-CG-4301_FAT1_chr4_187560875_-_DHX36_chr3_154001060_length(amino acids)=1458AA_start in transcript=210_stop in transcript=4586
MGRHLALLLLLLLLFQHFGDSDGSQRLEQTPLQFTHLEYNVTVQENSAAKTYVGHPVKMGVYITHPAWEVRYKIVSGDSENLFKAEEYIL
GDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEKNTNVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGT
NGEFYYSFKDRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRD
PAYAIVTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVTSPQF
KAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPAYSHLRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDRKASTKVL
VKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSIANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRA
SDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELDFFSLNPNSGVLSLKRSL
MDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTL
PTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQKAAWRLLHV
VVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTDTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQ
AREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSGAVRIVQQLD
FEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVG
VFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSS
NDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGF
VSSRNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY
DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQ

--------------------------------------------------------------
>In-frame_ENST00000441802_ENST00000329463_TCGA-CG-4301_FAT1_chr4_187560875_-_DHX36_chr3_154001060_length(transcript)=4587nt_BP=3852nt
AGCGTGAGGCGCCGGCGCCGAGCTGGGCGGCCGGGCGCGGGGAGAGGGCGCGGGAGCGGCTCGTGCGGCAGGTACCATGCGGACGCGCGA
GCCCGGCGAGGGCCCCGGCAGGCCCGGTCCCTGCTCGGGGGCGCGCTGAGACGGCGGGTGAGCTCCACGAGAGCGCCGTCGCCACTTCGG
GCCAACTTTGCGATTCCCGACAGTTAAGCAATGGGGAGACATTTGGCTTTGCTCCTGCTTCTGCTCCTTCTCTTCCAACATTTTGGAGAC
AGTGATGGCAGCCAACGACTTGAACAGACTCCTCTGCAGTTTACACACCTCGAGTACAACGTCACCGTGCAGGAGAACTCTGCAGCTAAG
ACTTATGTGGGGCATCCTGTCAAGATGGGTGTTTACATTACACATCCAGCGTGGGAAGTAAGGTACAAAATTGTTTCCGGAGACAGTGAA
AACCTGTTCAAAGCTGAAGAGTACATTCTCGGAGACTTTTGCTTTCTAAGAATAAGGACCAAAGGAGGAAATACAGCTATTCTTAATAGA
GAAGTGAAGGATCACTACACATTGATAGTGAAAGCACTTGAAAAAAATACTAATGTGGAGGCGCGAACAAAGGTCAGGGTGCAGGTGCTG
GATACAAATGACTTGAGACCGTTATTCTCACCCACCTCATACAGCGTTTCTTTACCTGAAAACACAGCTATAAGGACCAGTATCGCAAGA
GTCAGCGCCACGGATGCAGACATAGGAACCAACGGGGAATTTTACTACAGTTTTAAAGATCGAACAGATATGTTTGCTATTCACCCAACC
AGTGGTGTGATAGTGTTAACTGGTAGACTTGATTACCTAGAGACCAAGCTCTATGAGATGGAAATCCTCGCTGCGGACCGTGGCATGAAG
TTGTATGGGAGCAGTGGCATCAGCAGCATGGCCAAGCTAACGGTGCACATCGAACAGGCCAATGAATGTGCTCCGGTGATAACAGCAGTG
ACATTGTCACCATCAGAACTGGACAGGGACCCAGCATATGCAATTGTGACAGTGGATGACTGCGATCAGGGTGCCAATGGTGACATAGCA
TCTTTAAGCATCGTGGCAGGTGACCTTCTCCAGCAGTTTAGAACAGTGAGGTCCTTTCCAGGGAGTAAGGAGTATAAAGTCAAAGCCATC
GGTGGCATTGATTGGGACAGTCATCCTTTCGGCTACAATCTCACACTACAGGCTAAAGATAAAGGAACTCCGCCCCAGTTCTCTTCTGTT
AAAGTCATTCACGTGACTTCTCCACAGTTCAAAGCCGGGCCAGTCAAGTTTGAAAAGGATGTTTACAGAGCAGAAATAAGTGAATTTGCT
CCTCCCAACACACCTGTGGTCATGGTAAAGGCCATTCCTGCTTATTCCCATTTGAGGTATGTTTTTAAAAGTACACCTGGAAAAGCTAAA
TTCAGTTTAAATTACAACACTGGTCTCATTTCTATTTTAGAACCAGTTAAAAGACAGCAGGCAGCCCATTTTGAACTTGAAGTAACAACA
AGTGACAGAAAAGCGTCCACCAAGGTCTTGGTGAAAGTCTTAGGTGCAAATAGCAATCCCCCTGAATTTACCCAGACAGCGTACAAAGCT
GCTTTTGATGAGAACGTGCCCATTGGTACTACTGTCATGAGCCTGAGTGCCGTAGACCCTGATGAGGGTGAGAACGGGTACGTGACATAC
AGTATCGCAAATTTAAATCATGTGCCGTTTGCGATTGACCATTTCACTGGTGCCGTGAGTACGTCAGAAAACCTGGACTACGAACTGATG
CCTCGGGTTTATACTCTGAGGATTCGTGCATCAGACTGGGGCTTGCCGTACCGCCGGGAAGTCGAAGTCCTTGCTACAATTACTCTCAAT
AACTTGAATGACAACACACCTTTGTTTGAGAAAATAAATTGTGAAGGGACAATTCCCAGAGATCTAGGCGTGGGAGAGCAAATAACCACT
GTTTCTGCTATTGATGCAGATGAACTTCAGTTGGTACAGTATCAGATTGAAGCTGGAAATGAACTGGATTTCTTTAGTTTAAACCCCAAC
TCGGGGGTATTGTCATTAAAGCGATCGCTAATGGATGGCTTAGGTGCAAAGGTGTCTTTCCACAGTCTGAGAATCACAGCTACAGATGGA
GAAAATTTTGCCACACCATTATATATCAACATAACAGTGGCTGCCAGTCACAAGCTGGTAAACTTGCAGTGTGAAGAGACTGGTGTTGCC
AAAATGCTGGCAGAGAAGCTCCTGCAGGCAAATAAATTACACAACCAGGGAGAGGTGGAGGATATTTTCTTCGATTCTCACTCTGTCAAT
GCTCACATACCGCAGTTTAGAAGCACTCTTCCGACTGGTATTCAGGTAAAGGAAAACCAGCCTGTGGGTTCCAGTGTAATTTTCATGAAC
TCCACTGACCTTGACACTGGCTTCAATGGAAAACTGGTCTATGCTGTTTCTGGAGGAAATGAGGATAGTTGCTTCATGATTGATATGGAA
ACAGGAATGCTGAAAATTTTATCTCCTCTTGACCGTGAAACAACAGACAAATACACCCTGAATATTACCGTCTATGACCTTGGGATACCC
CAGAAGGCTGCGTGGCGTCTTCTACATGTCGTGGTTGTCGATGCCAATGATAATCCACCCGAGTTTTTACAGGAGAGCTATTTTGTGGAA
GTGAGTGAAGACAAGGAGGTACATAGTGAAATCATCCAGGTTGAAGCCACAGATAAAGACCTGGGGCCCAACGGACACGTGACGTACTCA
ATTGTTACAGACACAGACACATTTTCAATTGACAGCGTGACGGGTGTTGTTAACATCGCACGCCCTCTGGATCGAGAGCTGCAGCATGAG
CACTCCTTAAAGATTGAGGCCAGGGACCAAGCCAGAGAAGAGCCTCAGCTGTTCTCCACTGTCGTTGTGAAAGTATCACTAGAAGATGTT
AATGACAACCCACCTACATTTATTCCACCTAATTATCGTGTGAAAGTCCGAGAGGATCTTCCAGAAGGAACCGTCATCATGTGGTTAGAA
GCCCACGATCCTGATTTAGGTCAGTCTGGTCAGGTGAGATACAGCCTTCTGGACCACGGAGAAGGAAACTTCGATGTGGATAAACTCAGT
GGAGCAGTTAGGATCGTCCAGCAGTTGGACTTTGAGAAGAAGCAAGTGTATAATCTCACTGTGAGGGCCAAAGACAAGGGAAAGCCAGTT
TCTCTGTCTTCTACTTGCTATGTTGAAGTTGAGGTGGTTGATGTGAATGAGAACCTGCACCCACCCGTGTTTTCCAGCTTTGTGGAAAAG
GGGACAGTGAAAGAAGATGCACCTGTTGGTTCATTGGTAATGACGGTGTCGGCTCATGATGAGGACGCCAGAAGAGATGGGGAGATCCGA
TACTCCATTAGAGATGGCTCTGGCGTTGGTGTTTTCAAAATAGGTGAAGAGACAGGTGTCATAGAGACGTCAGATCGACTGGACCGTGAA
TCGACCTCCCATTATTGGCTAACAGTCTTTGCAACCGATCAGGGTGTCGTGCCTCTTTCATCGTTCATAGAGATCTACATAGAGGTTGAG
GATGTCAATGACAATGCACCACAGACATCAGAGCCTGTTTATTACCCAGAAATCATGGAAAATTCTCCTAAAGATGTATCTGTGGTCCAG
ATCGAGGCATTTGATCCAGATTCGAGCTCTAATGACAAGCTCATGTACAAAATTACAAGTGGAAATCCACAAGGATTCTTTTCAATACAT
CCTAAAACAGGTCTCATCACAACTACGTCAAGGAAGCTAGACCGAGAACAGCAAGATGAACACATATTAGAGGGCTGGGAAGAGGCTAGG
CGACGTGGTTTCAGATACGAAAAGGACTATTGCTGGGAATATTTTCTGTCTTCAAACACACTGCAGATGCTGCATAACATGAAAGGACAG
TTTGCTGAGCATCTTCTTGGAGCTGGATTTGTAAGCAGTAGAAATCCTAAAGATCCAGAATCTAATATAAATTCAGATAATGAGAAGATA
ATTAAAGCTGTCATCTGTGCTGGTTTATATCCCAAAGTTGCTAAAATTCGACTAAATTTGGGTAAAAAAAGAAAAATGGTAAAAGTTTAC
ACAAAAACCGATGGCCTGGTTGCTGTTCATCCTAAATCTGTTAATGTGGAGCAAACAGACTTTCACTACAACTGGCTTATCTATCACCTA
AAGATGAGAACAAGCAGTATATACTTGTATGACTGCACAGAGGTTTCCCCATACTGTCTCTTGTTTTTTGGAGGTGACATTTCCATCCAG
AAGGATAACGATCAGGAAACTATTGCTGTAGATGAGTGGATTGTATTTCAGTCTCCAGCAAGAATTGCCCATCTTGTTAAGGAATTAAGA
AAGGAACTAGATATTCTTCTGCAAGAGAAGATTGAAAGTCCTCATCCTGTAGACTGGAATGACACTAAATCCAGAGACTGTGCAGTACTG

>In-frame_ENST00000441802_ENST00000329463_TCGA-CG-4301_FAT1_chr4_187560875_-_DHX36_chr3_154001060_length(amino acids)=1458AA_start in transcript=210_stop in transcript=4586
MGRHLALLLLLLLLFQHFGDSDGSQRLEQTPLQFTHLEYNVTVQENSAAKTYVGHPVKMGVYITHPAWEVRYKIVSGDSENLFKAEEYIL
GDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEKNTNVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGT
NGEFYYSFKDRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRD
PAYAIVTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVTSPQF
KAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPAYSHLRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDRKASTKVL
VKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSIANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRA
SDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELDFFSLNPNSGVLSLKRSL
MDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTL
PTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQKAAWRLLHV
VVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTDTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQ
AREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSGAVRIVQQLD
FEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVG
VFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSS
NDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGF
VSSRNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY
DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FAT1-DHX36


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FAT1-DHX36


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FAT1-DHX36


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneFAT1C0009402Colorectal Carcinoma1CTD_human
HgeneFAT1C0009404Colorectal Neoplasms1CTD_human
HgeneFAT1C0010606Adenoid Cystic Carcinoma1CTD_human
HgeneFAT1C0017636Glioblastoma1CTD_human
HgeneFAT1C0018671Head and Neck Neoplasms1CTD_human
HgeneFAT1C0018675Head Neoplasms1CTD_human
HgeneFAT1C0023893Liver Cirrhosis, Experimental1CTD_human
HgeneFAT1C0027533Neck Neoplasms1CTD_human
HgeneFAT1C0036095Salivary Gland Neoplasms1CTD_human
HgeneFAT1C0220636Malignant neoplasm of salivary gland1CTD_human
HgeneFAT1C0278996Malignant Head and Neck Neoplasm1CTD_human
HgeneFAT1C0279626Squamous cell carcinoma of esophagus1CTD_human
HgeneFAT1C0334588Giant Cell Glioblastoma1CTD_human
HgeneFAT1C0746787Cancer of Neck1CTD_human
HgeneFAT1C0751177Cancer of Head1CTD_human
HgeneFAT1C0887900Upper Aerodigestive Tract Neoplasms1CTD_human
HgeneFAT1C1621958Glioblastoma Multiforme1CTD_human