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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FBXL5-RAB28 (FusionGDB2 ID:29633)

Fusion Gene Summary for FBXL5-RAB28

check button Fusion gene summary
Fusion gene informationFusion gene name: FBXL5-RAB28
Fusion gene ID: 29633
HgeneTgene
Gene symbol

FBXL5

RAB28

Gene ID

26234

9364

Gene nameF-box and leucine rich repeat protein 5RAB28, member RAS oncogene family
SynonymsFBL4|FBL5|FLR1CORD18
Cytomap

4p15.32

4p15.33

Type of geneprotein-codingprotein-coding
DescriptionF-box/LRR-repeat protein 5F-box protein FBL4/FBL5p45SKP2-like proteinras-related protein Rab-28
Modification date2020031320200313
UniProtAcc

Q9UKA1

.
Ensembl transtripts involved in fusion geneENST00000341285, ENST00000412094, 
ENST00000382358, ENST00000514541, 
ENST00000330852, ENST00000288723, 
ENST00000338176, 
Fusion gene scores* DoF score8 X 7 X 6=3365 X 4 X 5=100
# samples 106
** MAII scorelog2(10/336*10)=-1.74846123300404
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/100*10)=-0.736965594166206
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FBXL5 [Title/Abstract] AND RAB28 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFBXL5(15656827)-RAB28(13481150), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFBXL5

GO:0016567

protein ubiquitination

17532294|19762596|19762597

HgeneFBXL5

GO:0031146

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

17532294|19762596|19762597


check buttonFusion gene breakpoints across FBXL5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across RAB28 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-M7-A724-01AFBXL5chr4

15656827

-RAB28chr4

13481150

-
ChimerDB4PRADTCGA-M7-A724FBXL5chr4

15656826

-RAB28chr4

13481150

-
ChimerDB4PRADTCGA-M7-A724FBXL5chr4

15656826

-RAB28chr4

13481150

-
ChimerDB4PRADTCGA-M7-A724FBXL5chr4

15656827

-RAB28chr4

13481150

-
ChimerDB4PRADTCGA-M7-A724-01AFBXL5chr4

15656827

-RAB28chr4

13481150

-


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Fusion Gene ORF analysis for FBXL5-RAB28

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000341285ENST00000330852FBXL5chr4

15656827

-RAB28chr4

13481150

-
In-frameENST00000341285ENST00000288723FBXL5chr4

15656827

-RAB28chr4

13481150

-
In-frameENST00000341285ENST00000338176FBXL5chr4

15656827

-RAB28chr4

13481150

-
In-frameENST00000412094ENST00000330852FBXL5chr4

15656827

-RAB28chr4

13481150

-
In-frameENST00000412094ENST00000288723FBXL5chr4

15656827

-RAB28chr4

13481150

-
In-frameENST00000412094ENST00000338176FBXL5chr4

15656827

-RAB28chr4

13481150

-
5UTR-3CDSENST00000382358ENST00000330852FBXL5chr4

15656827

-RAB28chr4

13481150

-
5UTR-3CDSENST00000382358ENST00000288723FBXL5chr4

15656827

-RAB28chr4

13481150

-
5UTR-3CDSENST00000382358ENST00000338176FBXL5chr4

15656827

-RAB28chr4

13481150

-
intron-3CDSENST00000514541ENST00000330852FBXL5chr4

15656827

-RAB28chr4

13481150

-
intron-3CDSENST00000514541ENST00000288723FBXL5chr4

15656827

-RAB28chr4

13481150

-
intron-3CDSENST00000514541ENST00000338176FBXL5chr4

15656827

-RAB28chr4

13481150

-
In-frameENST00000341285ENST00000330852FBXL5chr4

15656826

-RAB28chr4

13481150

-
In-frameENST00000341285ENST00000288723FBXL5chr4

15656826

-RAB28chr4

13481150

-
In-frameENST00000341285ENST00000338176FBXL5chr4

15656826

-RAB28chr4

13481150

-
In-frameENST00000412094ENST00000330852FBXL5chr4

15656826

-RAB28chr4

13481150

-
In-frameENST00000412094ENST00000288723FBXL5chr4

15656826

-RAB28chr4

13481150

-
In-frameENST00000412094ENST00000338176FBXL5chr4

15656826

-RAB28chr4

13481150

-
5UTR-3CDSENST00000382358ENST00000330852FBXL5chr4

15656826

-RAB28chr4

13481150

-
5UTR-3CDSENST00000382358ENST00000288723FBXL5chr4

15656826

-RAB28chr4

13481150

-
5UTR-3CDSENST00000382358ENST00000338176FBXL5chr4

15656826

-RAB28chr4

13481150

-
intron-3CDSENST00000514541ENST00000330852FBXL5chr4

15656826

-RAB28chr4

13481150

-
intron-3CDSENST00000514541ENST00000288723FBXL5chr4

15656826

-RAB28chr4

13481150

-
intron-3CDSENST00000514541ENST00000338176FBXL5chr4

15656826

-RAB28chr4

13481150

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000341285FBXL5chr415656827-ENST00000330852RAB28chr413481150-163420953799248
ENST00000341285FBXL5chr415656827-ENST00000288723RAB28chr413481150-172920953796247
ENST00000341285FBXL5chr415656827-ENST00000338176RAB28chr413481150-170620953748231
ENST00000412094FBXL5chr415656827-ENST00000330852RAB28chr413481150-160417923769248
ENST00000412094FBXL5chr415656827-ENST00000288723RAB28chr413481150-169917923766247
ENST00000412094FBXL5chr415656827-ENST00000338176RAB28chr413481150-167617923718231
ENST00000341285FBXL5chr415656826-ENST00000330852RAB28chr413481150-163420953799248
ENST00000341285FBXL5chr415656826-ENST00000288723RAB28chr413481150-172920953796247
ENST00000341285FBXL5chr415656826-ENST00000338176RAB28chr413481150-170620953748231
ENST00000412094FBXL5chr415656826-ENST00000330852RAB28chr413481150-160417923769248
ENST00000412094FBXL5chr415656826-ENST00000288723RAB28chr413481150-169917923766247
ENST00000412094FBXL5chr415656826-ENST00000338176RAB28chr413481150-167617923718231

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000341285ENST00000330852FBXL5chr415656827-RAB28chr413481150-0.0005267360.9994733
ENST00000341285ENST00000288723FBXL5chr415656827-RAB28chr413481150-0.0007056530.9992943
ENST00000341285ENST00000338176FBXL5chr415656827-RAB28chr413481150-0.0008378960.9991621
ENST00000412094ENST00000330852FBXL5chr415656827-RAB28chr413481150-0.0005063940.9994936
ENST00000412094ENST00000288723FBXL5chr415656827-RAB28chr413481150-0.0006856460.9993143
ENST00000412094ENST00000338176FBXL5chr415656827-RAB28chr413481150-0.0007749950.999225
ENST00000341285ENST00000330852FBXL5chr415656826-RAB28chr413481150-0.0005267360.9994733
ENST00000341285ENST00000288723FBXL5chr415656826-RAB28chr413481150-0.0007056530.9992943
ENST00000341285ENST00000338176FBXL5chr415656826-RAB28chr413481150-0.0008378960.9991621
ENST00000412094ENST00000330852FBXL5chr415656826-RAB28chr413481150-0.0005063940.9994936
ENST00000412094ENST00000288723FBXL5chr415656826-RAB28chr413481150-0.0006856460.9993143
ENST00000412094ENST00000338176FBXL5chr415656826-RAB28chr413481150-0.0007749950.999225

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Fusion Genomic Features for FBXL5-RAB28


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FBXL5-RAB28


check button Go to

FGviewer for the breakpoints of chr4:15656827-chr4:13481150

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FBXL5

Q9UKA1

.
FUNCTION: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued. {ECO:0000269|PubMed:17532294, ECO:0000269|PubMed:19762596, ECO:0000269|PubMed:19762597}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRAB28chr4:15656826chr4:13481150ENST000002887230841_4925.0432.6666666666667MotifEffector region
TgeneRAB28chr4:15656826chr4:13481150ENST000003308520741_4925.0222.0MotifEffector region
TgeneRAB28chr4:15656826chr4:13481150ENST000003381760841_4925.0409.0MotifEffector region
TgeneRAB28chr4:15656827chr4:13481150ENST000002887230841_4925.0432.6666666666667MotifEffector region
TgeneRAB28chr4:15656827chr4:13481150ENST000003308520741_4925.0222.0MotifEffector region
TgeneRAB28chr4:15656827chr4:13481150ENST000003381760841_4925.0409.0MotifEffector region
TgeneRAB28chr4:15656826chr4:13481150ENST0000028872308129_13225.0432.6666666666667Nucleotide bindingGTP
TgeneRAB28chr4:15656826chr4:13481150ENST0000028872308159_16125.0432.6666666666667Nucleotide bindingGTP
TgeneRAB28chr4:15656826chr4:13481150ENST000002887230868_7225.0432.6666666666667Nucleotide bindingGTP
TgeneRAB28chr4:15656826chr4:13481150ENST0000033085207129_13225.0222.0Nucleotide bindingGTP
TgeneRAB28chr4:15656826chr4:13481150ENST0000033085207159_16125.0222.0Nucleotide bindingGTP
TgeneRAB28chr4:15656826chr4:13481150ENST000003308520768_7225.0222.0Nucleotide bindingGTP
TgeneRAB28chr4:15656826chr4:13481150ENST0000033817608129_13225.0409.0Nucleotide bindingGTP
TgeneRAB28chr4:15656826chr4:13481150ENST0000033817608159_16125.0409.0Nucleotide bindingGTP
TgeneRAB28chr4:15656826chr4:13481150ENST000003381760868_7225.0409.0Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST0000028872308129_13225.0432.6666666666667Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST0000028872308159_16125.0432.6666666666667Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST000002887230868_7225.0432.6666666666667Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST0000033085207129_13225.0222.0Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST0000033085207159_16125.0222.0Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST000003308520768_7225.0222.0Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST0000033817608129_13225.0409.0Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST0000033817608159_16125.0409.0Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST000003381760868_7225.0409.0Nucleotide bindingGTP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFBXL5chr4:15656826chr4:13481150ENST00000341285-111202_24828.0692.0DomainF-box
HgeneFBXL5chr4:15656826chr4:13481150ENST00000382358-112202_2480566.0DomainF-box
HgeneFBXL5chr4:15656826chr4:13481150ENST00000412094-111202_24828.0675.0DomainF-box
HgeneFBXL5chr4:15656827chr4:13481150ENST00000341285-111202_24828.0692.0DomainF-box
HgeneFBXL5chr4:15656827chr4:13481150ENST00000382358-112202_2480566.0DomainF-box
HgeneFBXL5chr4:15656827chr4:13481150ENST00000412094-111202_24828.0675.0DomainF-box
HgeneFBXL5chr4:15656826chr4:13481150ENST00000341285-1111_15928.0692.0RegionNote=Hemerythrin-like
HgeneFBXL5chr4:15656826chr4:13481150ENST00000382358-1121_1590566.0RegionNote=Hemerythrin-like
HgeneFBXL5chr4:15656826chr4:13481150ENST00000412094-1111_15928.0675.0RegionNote=Hemerythrin-like
HgeneFBXL5chr4:15656827chr4:13481150ENST00000341285-1111_15928.0692.0RegionNote=Hemerythrin-like
HgeneFBXL5chr4:15656827chr4:13481150ENST00000382358-1121_1590566.0RegionNote=Hemerythrin-like
HgeneFBXL5chr4:15656827chr4:13481150ENST00000412094-1111_15928.0675.0RegionNote=Hemerythrin-like
HgeneFBXL5chr4:15656826chr4:13481150ENST00000341285-111340_36428.0692.0RepeatNote=LRR 1
HgeneFBXL5chr4:15656826chr4:13481150ENST00000341285-111365_39228.0692.0RepeatNote=LRR 2
HgeneFBXL5chr4:15656826chr4:13481150ENST00000341285-111393_41828.0692.0RepeatNote=LRR 3
HgeneFBXL5chr4:15656826chr4:13481150ENST00000341285-111479_50828.0692.0RepeatNote=LRR 4
HgeneFBXL5chr4:15656826chr4:13481150ENST00000341285-111576_60728.0692.0RepeatNote=LRR 5
HgeneFBXL5chr4:15656826chr4:13481150ENST00000341285-111608_63528.0692.0RepeatNote=LRR 6
HgeneFBXL5chr4:15656826chr4:13481150ENST00000341285-111636_66128.0692.0RepeatNote=LRR 7
HgeneFBXL5chr4:15656826chr4:13481150ENST00000382358-112340_3640566.0RepeatNote=LRR 1
HgeneFBXL5chr4:15656826chr4:13481150ENST00000382358-112365_3920566.0RepeatNote=LRR 2
HgeneFBXL5chr4:15656826chr4:13481150ENST00000382358-112393_4180566.0RepeatNote=LRR 3
HgeneFBXL5chr4:15656826chr4:13481150ENST00000382358-112479_5080566.0RepeatNote=LRR 4
HgeneFBXL5chr4:15656826chr4:13481150ENST00000382358-112576_6070566.0RepeatNote=LRR 5
HgeneFBXL5chr4:15656826chr4:13481150ENST00000382358-112608_6350566.0RepeatNote=LRR 6
HgeneFBXL5chr4:15656826chr4:13481150ENST00000382358-112636_6610566.0RepeatNote=LRR 7
HgeneFBXL5chr4:15656826chr4:13481150ENST00000412094-111340_36428.0675.0RepeatNote=LRR 1
HgeneFBXL5chr4:15656826chr4:13481150ENST00000412094-111365_39228.0675.0RepeatNote=LRR 2
HgeneFBXL5chr4:15656826chr4:13481150ENST00000412094-111393_41828.0675.0RepeatNote=LRR 3
HgeneFBXL5chr4:15656826chr4:13481150ENST00000412094-111479_50828.0675.0RepeatNote=LRR 4
HgeneFBXL5chr4:15656826chr4:13481150ENST00000412094-111576_60728.0675.0RepeatNote=LRR 5
HgeneFBXL5chr4:15656826chr4:13481150ENST00000412094-111608_63528.0675.0RepeatNote=LRR 6
HgeneFBXL5chr4:15656826chr4:13481150ENST00000412094-111636_66128.0675.0RepeatNote=LRR 7
HgeneFBXL5chr4:15656827chr4:13481150ENST00000341285-111340_36428.0692.0RepeatNote=LRR 1
HgeneFBXL5chr4:15656827chr4:13481150ENST00000341285-111365_39228.0692.0RepeatNote=LRR 2
HgeneFBXL5chr4:15656827chr4:13481150ENST00000341285-111393_41828.0692.0RepeatNote=LRR 3
HgeneFBXL5chr4:15656827chr4:13481150ENST00000341285-111479_50828.0692.0RepeatNote=LRR 4
HgeneFBXL5chr4:15656827chr4:13481150ENST00000341285-111576_60728.0692.0RepeatNote=LRR 5
HgeneFBXL5chr4:15656827chr4:13481150ENST00000341285-111608_63528.0692.0RepeatNote=LRR 6
HgeneFBXL5chr4:15656827chr4:13481150ENST00000341285-111636_66128.0692.0RepeatNote=LRR 7
HgeneFBXL5chr4:15656827chr4:13481150ENST00000382358-112340_3640566.0RepeatNote=LRR 1
HgeneFBXL5chr4:15656827chr4:13481150ENST00000382358-112365_3920566.0RepeatNote=LRR 2
HgeneFBXL5chr4:15656827chr4:13481150ENST00000382358-112393_4180566.0RepeatNote=LRR 3
HgeneFBXL5chr4:15656827chr4:13481150ENST00000382358-112479_5080566.0RepeatNote=LRR 4
HgeneFBXL5chr4:15656827chr4:13481150ENST00000382358-112576_6070566.0RepeatNote=LRR 5
HgeneFBXL5chr4:15656827chr4:13481150ENST00000382358-112608_6350566.0RepeatNote=LRR 6
HgeneFBXL5chr4:15656827chr4:13481150ENST00000382358-112636_6610566.0RepeatNote=LRR 7
HgeneFBXL5chr4:15656827chr4:13481150ENST00000412094-111340_36428.0675.0RepeatNote=LRR 1
HgeneFBXL5chr4:15656827chr4:13481150ENST00000412094-111365_39228.0675.0RepeatNote=LRR 2
HgeneFBXL5chr4:15656827chr4:13481150ENST00000412094-111393_41828.0675.0RepeatNote=LRR 3
HgeneFBXL5chr4:15656827chr4:13481150ENST00000412094-111479_50828.0675.0RepeatNote=LRR 4
HgeneFBXL5chr4:15656827chr4:13481150ENST00000412094-111576_60728.0675.0RepeatNote=LRR 5
HgeneFBXL5chr4:15656827chr4:13481150ENST00000412094-111608_63528.0675.0RepeatNote=LRR 6
HgeneFBXL5chr4:15656827chr4:13481150ENST00000412094-111636_66128.0675.0RepeatNote=LRR 7
TgeneRAB28chr4:15656826chr4:13481150ENST000002887230819_2725.0432.6666666666667Nucleotide bindingGTP
TgeneRAB28chr4:15656826chr4:13481150ENST000003308520719_2725.0222.0Nucleotide bindingGTP
TgeneRAB28chr4:15656826chr4:13481150ENST000003381760819_2725.0409.0Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST000002887230819_2725.0432.6666666666667Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST000003308520719_2725.0222.0Nucleotide bindingGTP
TgeneRAB28chr4:15656827chr4:13481150ENST000003381760819_2725.0409.0Nucleotide bindingGTP


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Fusion Gene Sequence for FBXL5-RAB28


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000341285_ENST00000330852_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(transcript)=1634nt_BP=209nt
ACCGGGCGCGCGCGCCGACGGGGCGGGCGCATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGG
CCGCGGCTGCTGAGGCGGAGGCTGAGGCAGTGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGA
AGCAGCTGGTGGGGCTCTACTGCGACAAGACCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAG
GACTGGATTTCTTTTTGAGAAGGATAACATTGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAG
GCAAAATGTTGGATAAATATATCTATGGAGCACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAG
ATTGGTATACTGTGGTGAAGAAAGTGAGCGAGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATA
TGCGAACAATAAAACCTGAAAAACACTTACGGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTG
TCTTCCTGTGCTTTCAGAAAGTTGCTGCTGAAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGAGGGTGGTGAAGG
CAGATATTGTAAACTACAACCAGGAACCTATGTCAAGGACTGTTAACCCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCATTTTT
CTTTTGTGTTGATAGTTCTGGCTGCCCTTCACCTCTGGGTGGGCCCGAGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCTGTAGT
TCAGTTAACACTTTACTCCCAACTTGCTTCATCATTGCTATTGCCTCACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAACTTTG
GGACCACACACTTTGAATTCAAAATGGAAAACCCATTCCCTGGAATTAGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTGTATGT
CCTTGCTTCTTTTTTCATTGATGTAAATTTTTTTAACTTAATATGAAAACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCACAGCA
ATTTCATTCTCTTATCGGAACTTGTATGTGTCAAAGTATACTTCAGAGTGCAAACATTAAGCAAGTAATATATTTTACCTACAGATACTT
ATGAAGACATTCTTTCGCTATCGTGAGTAAAAGTATATAAAGCTGTTTCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAATATTT
TTTCATTTTTTAAAAAAGGGCCTAAATTGTTTATATTGTAGTTTGTAACTCACAAAGTAATATTTGATATTGTATTTTTATTACTGTATC
GTTGTCGTTATGTATTGTGTAATACTCAGGTTTGAAGGCTTTCTGAATTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTTCTCTT
GCAAACTGCATAAGAGTACTCCCGAGAATGAGTTATGACATTGTGGATCAGACTGTACCTGATGTTCAGATGTTTTTCTTTCACAAATAA

>In-frame_ENST00000341285_ENST00000330852_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(amino acids)=248AA_start in transcript=53_stop in transcript=799
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------
>In-frame_ENST00000341285_ENST00000288723_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(transcript)=1729nt_BP=209nt
ACCGGGCGCGCGCGCCGACGGGGCGGGCGCATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGG
CCGCGGCTGCTGAGGCGGAGGCTGAGGCAGTGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGA
AGCAGCTGGTGGGGCTCTACTGCGACAAGACCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAG
GACTGGATTTCTTTTTGAGAAGGATAACATTGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAG
GCAAAATGTTGGATAAATATATCTATGGAGCACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAG
ATTGGTATACTGTGGTGAAGAAAGTGAGCGAGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATA
TGCGAACAATAAAACCTGAAAAACACTTACGGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTG
TCTTCCTGTGCTTTCAGAAAGTTGCTGCTGAAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGCGTATTGTCAGGG
CAGAAATAGTGAAGTACCCGGAAGAAGAAAATCAACATACCACCTCTACTCAGAGTAGAATCTGTTCAGTACAGTAGTGCAGAGGGTGGT
GAAGGCAGATATTGTAAACTACAACCAGGAACCTATGTCAAGGACTGTTAACCCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCA
TTTTTCTTTTGTGTTGATAGTTCTGGCTGCCCTTCACCTCTGGGTGGGCCCGAGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCT
GTAGTTCAGTTAACACTTTACTCCCAACTTGCTTCATCATTGCTATTGCCTCACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAA
CTTTGGGACCACACACTTTGAATTCAAAATGGAAAACCCATTCCCTGGAATTAGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTG
TATGTCCTTGCTTCTTTTTTCATTGATGTAAATTTTTTTAACTTAATATGAAAACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCA
CAGCAATTTCATTCTCTTATCGGAACTTGTATGTGTCAAAGTATACTTCAGAGTGCAAACATTAAGCAAGTAATATATTTTACCTACAGA
TACTTATGAAGACATTCTTTCGCTATCGTGAGTAAAAGTATATAAAGCTGTTTCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAA
TATTTTTTCATTTTTTAAAAAAGGGCCTAAATTGTTTATATTGTAGTTTGTAACTCACAAAGTAATATTTGATATTGTATTTTTATTACT
GTATCGTTGTCGTTATGTATTGTGTAATACTCAGGTTTGAAGGCTTTCTGAATTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTT
CTCTTGCAAACTGCATAAGAGTACTCCCGAGAATGAGTTATGACATTGTGGATCAGACTGTACCTGATGTTCAGATGTTTTTCTTTCACA

>In-frame_ENST00000341285_ENST00000288723_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(amino acids)=247AA_start in transcript=53_stop in transcript=796
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------
>In-frame_ENST00000341285_ENST00000338176_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(transcript)=1706nt_BP=209nt
ACCGGGCGCGCGCGCCGACGGGGCGGGCGCATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGG
CCGCGGCTGCTGAGGCGGAGGCTGAGGCAGTGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGA
AGCAGCTGGTGGGGCTCTACTGCGACAAGACCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAG
GACTGGATTTCTTTTTGAGAAGGATAACATTGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAG
GCAAAATGTTGGATAAATATATCTATGGAGCACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAG
ATTGGTATACTGTGGTGAAGAAAGTGAGCGAGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATA
TGCGAACAATAAAACCTGAAAAACACTTACGGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTG
TCTTCCTGTGCTTTCAGAAAGTTGCTGCTGAAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGGGCCATTTCATTA
TTTTCATTTCATCAACTAATAGAGAATAATCGAGTGTGCTTTGTGGCTCTAAAAATAAAGAGGGTGGTGAAGGCAGATATTGTAAACTAC
AACCAGGAACCTATGTCAAGGACTGTTAACCCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCATTTTTCTTTTGTGTTGATAGTT
CTGGCTGCCCTTCACCTCTGGGTGGGCCCGAGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCTGTAGTTCAGTTAACACTTTACT
CCCAACTTGCTTCATCATTGCTATTGCCTCACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAACTTTGGGACCACACACTTTGAA
TTCAAAATGGAAAACCCATTCCCTGGAATTAGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTGTATGTCCTTGCTTCTTTTTTCA
TTGATGTAAATTTTTTTAACTTAATATGAAAACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCACAGCAATTTCATTCTCTTATCG
GAACTTGTATGTGTCAAAGTATACTTCAGAGTGCAAACATTAAGCAAGTAATATATTTTACCTACAGATACTTATGAAGACATTCTTTCG
CTATCGTGAGTAAAAGTATATAAAGCTGTTTCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAATATTTTTTCATTTTTTAAAAAA
GGGCCTAAATTGTTTATATTGTAGTTTGTAACTCACAAAGTAATATTTGATATTGTATTTTTATTACTGTATCGTTGTCGTTATGTATTG
TGTAATACTCAGGTTTGAAGGCTTTCTGAATTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTTCTCTTGCAAACTGCATAAGAGT

>In-frame_ENST00000341285_ENST00000338176_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(amino acids)=231AA_start in transcript=53_stop in transcript=748
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------
>In-frame_ENST00000412094_ENST00000330852_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(transcript)=1604nt_BP=179nt
ATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGGCCGCGGCTGCTGAGGCGGAGGCTGAGGCAG
TGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGAAGCAGCTGGTGGGGCTCTACTGCGACAAGA
CCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAGGACTGGATTTCTTTTTGAGAAGGATAACAT
TGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAGGCAAAATGTTGGATAAATATATCTATGGAG
CACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAGATTGGTATACTGTGGTGAAGAAAGTGAGCG
AGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATATGCGAACAATAAAACCTGAAAAACACTTAC
GGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTGTCTTCCTGTGCTTTCAGAAAGTTGCTGCTG
AAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGAGGGTGGTGAAGGCAGATATTGTAAACTACAACCAGGAACCTA
TGTCAAGGACTGTTAACCCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCATTTTTCTTTTGTGTTGATAGTTCTGGCTGCCCTTC
ACCTCTGGGTGGGCCCGAGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCTGTAGTTCAGTTAACACTTTACTCCCAACTTGCTTC
ATCATTGCTATTGCCTCACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAACTTTGGGACCACACACTTTGAATTCAAAATGGAAA
ACCCATTCCCTGGAATTAGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTGTATGTCCTTGCTTCTTTTTTCATTGATGTAAATTT
TTTTAACTTAATATGAAAACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCACAGCAATTTCATTCTCTTATCGGAACTTGTATGTG
TCAAAGTATACTTCAGAGTGCAAACATTAAGCAAGTAATATATTTTACCTACAGATACTTATGAAGACATTCTTTCGCTATCGTGAGTAA
AAGTATATAAAGCTGTTTCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAATATTTTTTCATTTTTTAAAAAAGGGCCTAAATTGT
TTATATTGTAGTTTGTAACTCACAAAGTAATATTTGATATTGTATTTTTATTACTGTATCGTTGTCGTTATGTATTGTGTAATACTCAGG
TTTGAAGGCTTTCTGAATTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTTCTCTTGCAAACTGCATAAGAGTACTCCCGAGAATG

>In-frame_ENST00000412094_ENST00000330852_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(amino acids)=248AA_start in transcript=23_stop in transcript=769
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------
>In-frame_ENST00000412094_ENST00000288723_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(transcript)=1699nt_BP=179nt
ATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGGCCGCGGCTGCTGAGGCGGAGGCTGAGGCAG
TGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGAAGCAGCTGGTGGGGCTCTACTGCGACAAGA
CCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAGGACTGGATTTCTTTTTGAGAAGGATAACAT
TGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAGGCAAAATGTTGGATAAATATATCTATGGAG
CACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAGATTGGTATACTGTGGTGAAGAAAGTGAGCG
AGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATATGCGAACAATAAAACCTGAAAAACACTTAC
GGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTGTCTTCCTGTGCTTTCAGAAAGTTGCTGCTG
AAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGCGTATTGTCAGGGCAGAAATAGTGAAGTACCCGGAAGAAGAAA
ATCAACATACCACCTCTACTCAGAGTAGAATCTGTTCAGTACAGTAGTGCAGAGGGTGGTGAAGGCAGATATTGTAAACTACAACCAGGA
ACCTATGTCAAGGACTGTTAACCCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCATTTTTCTTTTGTGTTGATAGTTCTGGCTGC
CCTTCACCTCTGGGTGGGCCCGAGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCTGTAGTTCAGTTAACACTTTACTCCCAACTT
GCTTCATCATTGCTATTGCCTCACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAACTTTGGGACCACACACTTTGAATTCAAAAT
GGAAAACCCATTCCCTGGAATTAGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTGTATGTCCTTGCTTCTTTTTTCATTGATGTA
AATTTTTTTAACTTAATATGAAAACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCACAGCAATTTCATTCTCTTATCGGAACTTGT
ATGTGTCAAAGTATACTTCAGAGTGCAAACATTAAGCAAGTAATATATTTTACCTACAGATACTTATGAAGACATTCTTTCGCTATCGTG
AGTAAAAGTATATAAAGCTGTTTCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAATATTTTTTCATTTTTTAAAAAAGGGCCTAA
ATTGTTTATATTGTAGTTTGTAACTCACAAAGTAATATTTGATATTGTATTTTTATTACTGTATCGTTGTCGTTATGTATTGTGTAATAC
TCAGGTTTGAAGGCTTTCTGAATTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTTCTCTTGCAAACTGCATAAGAGTACTCCCGA

>In-frame_ENST00000412094_ENST00000288723_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(amino acids)=247AA_start in transcript=23_stop in transcript=766
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------
>In-frame_ENST00000412094_ENST00000338176_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(transcript)=1676nt_BP=179nt
ATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGGCCGCGGCTGCTGAGGCGGAGGCTGAGGCAG
TGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGAAGCAGCTGGTGGGGCTCTACTGCGACAAGA
CCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAGGACTGGATTTCTTTTTGAGAAGGATAACAT
TGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAGGCAAAATGTTGGATAAATATATCTATGGAG
CACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAGATTGGTATACTGTGGTGAAGAAAGTGAGCG
AGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATATGCGAACAATAAAACCTGAAAAACACTTAC
GGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTGTCTTCCTGTGCTTTCAGAAAGTTGCTGCTG
AAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGGGCCATTTCATTATTTTCATTTCATCAACTAATAGAGAATAAT
CGAGTGTGCTTTGTGGCTCTAAAAATAAAGAGGGTGGTGAAGGCAGATATTGTAAACTACAACCAGGAACCTATGTCAAGGACTGTTAAC
CCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCATTTTTCTTTTGTGTTGATAGTTCTGGCTGCCCTTCACCTCTGGGTGGGCCCG
AGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCTGTAGTTCAGTTAACACTTTACTCCCAACTTGCTTCATCATTGCTATTGCCTC
ACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAACTTTGGGACCACACACTTTGAATTCAAAATGGAAAACCCATTCCCTGGAATT
AGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTGTATGTCCTTGCTTCTTTTTTCATTGATGTAAATTTTTTTAACTTAATATGAA
AACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCACAGCAATTTCATTCTCTTATCGGAACTTGTATGTGTCAAAGTATACTTCAGA
GTGCAAACATTAAGCAAGTAATATATTTTACCTACAGATACTTATGAAGACATTCTTTCGCTATCGTGAGTAAAAGTATATAAAGCTGTT
TCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAATATTTTTTCATTTTTTAAAAAAGGGCCTAAATTGTTTATATTGTAGTTTGTA
ACTCACAAAGTAATATTTGATATTGTATTTTTATTACTGTATCGTTGTCGTTATGTATTGTGTAATACTCAGGTTTGAAGGCTTTCTGAA
TTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTTCTCTTGCAAACTGCATAAGAGTACTCCCGAGAATGAGTTATGACATTGTGGA

>In-frame_ENST00000412094_ENST00000338176_TCGA-M7-A724-01A_FBXL5_chr4_15656827_-_RAB28_chr4_13481150_length(amino acids)=231AA_start in transcript=23_stop in transcript=718
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------
>In-frame_ENST00000341285_ENST00000330852_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(transcript)=1634nt_BP=209nt
ACCGGGCGCGCGCGCCGACGGGGCGGGCGCATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGG
CCGCGGCTGCTGAGGCGGAGGCTGAGGCAGTGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGA
AGCAGCTGGTGGGGCTCTACTGCGACAAGACCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAG
GACTGGATTTCTTTTTGAGAAGGATAACATTGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAG
GCAAAATGTTGGATAAATATATCTATGGAGCACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAG
ATTGGTATACTGTGGTGAAGAAAGTGAGCGAGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATA
TGCGAACAATAAAACCTGAAAAACACTTACGGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTG
TCTTCCTGTGCTTTCAGAAAGTTGCTGCTGAAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGAGGGTGGTGAAGG
CAGATATTGTAAACTACAACCAGGAACCTATGTCAAGGACTGTTAACCCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCATTTTT
CTTTTGTGTTGATAGTTCTGGCTGCCCTTCACCTCTGGGTGGGCCCGAGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCTGTAGT
TCAGTTAACACTTTACTCCCAACTTGCTTCATCATTGCTATTGCCTCACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAACTTTG
GGACCACACACTTTGAATTCAAAATGGAAAACCCATTCCCTGGAATTAGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTGTATGT
CCTTGCTTCTTTTTTCATTGATGTAAATTTTTTTAACTTAATATGAAAACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCACAGCA
ATTTCATTCTCTTATCGGAACTTGTATGTGTCAAAGTATACTTCAGAGTGCAAACATTAAGCAAGTAATATATTTTACCTACAGATACTT
ATGAAGACATTCTTTCGCTATCGTGAGTAAAAGTATATAAAGCTGTTTCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAATATTT
TTTCATTTTTTAAAAAAGGGCCTAAATTGTTTATATTGTAGTTTGTAACTCACAAAGTAATATTTGATATTGTATTTTTATTACTGTATC
GTTGTCGTTATGTATTGTGTAATACTCAGGTTTGAAGGCTTTCTGAATTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTTCTCTT
GCAAACTGCATAAGAGTACTCCCGAGAATGAGTTATGACATTGTGGATCAGACTGTACCTGATGTTCAGATGTTTTTCTTTCACAAATAA

>In-frame_ENST00000341285_ENST00000330852_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(amino acids)=248AA_start in transcript=53_stop in transcript=799
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------
>In-frame_ENST00000341285_ENST00000288723_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(transcript)=1729nt_BP=209nt
ACCGGGCGCGCGCGCCGACGGGGCGGGCGCATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGG
CCGCGGCTGCTGAGGCGGAGGCTGAGGCAGTGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGA
AGCAGCTGGTGGGGCTCTACTGCGACAAGACCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAG
GACTGGATTTCTTTTTGAGAAGGATAACATTGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAG
GCAAAATGTTGGATAAATATATCTATGGAGCACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAG
ATTGGTATACTGTGGTGAAGAAAGTGAGCGAGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATA
TGCGAACAATAAAACCTGAAAAACACTTACGGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTG
TCTTCCTGTGCTTTCAGAAAGTTGCTGCTGAAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGCGTATTGTCAGGG
CAGAAATAGTGAAGTACCCGGAAGAAGAAAATCAACATACCACCTCTACTCAGAGTAGAATCTGTTCAGTACAGTAGTGCAGAGGGTGGT
GAAGGCAGATATTGTAAACTACAACCAGGAACCTATGTCAAGGACTGTTAACCCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCA
TTTTTCTTTTGTGTTGATAGTTCTGGCTGCCCTTCACCTCTGGGTGGGCCCGAGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCT
GTAGTTCAGTTAACACTTTACTCCCAACTTGCTTCATCATTGCTATTGCCTCACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAA
CTTTGGGACCACACACTTTGAATTCAAAATGGAAAACCCATTCCCTGGAATTAGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTG
TATGTCCTTGCTTCTTTTTTCATTGATGTAAATTTTTTTAACTTAATATGAAAACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCA
CAGCAATTTCATTCTCTTATCGGAACTTGTATGTGTCAAAGTATACTTCAGAGTGCAAACATTAAGCAAGTAATATATTTTACCTACAGA
TACTTATGAAGACATTCTTTCGCTATCGTGAGTAAAAGTATATAAAGCTGTTTCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAA
TATTTTTTCATTTTTTAAAAAAGGGCCTAAATTGTTTATATTGTAGTTTGTAACTCACAAAGTAATATTTGATATTGTATTTTTATTACT
GTATCGTTGTCGTTATGTATTGTGTAATACTCAGGTTTGAAGGCTTTCTGAATTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTT
CTCTTGCAAACTGCATAAGAGTACTCCCGAGAATGAGTTATGACATTGTGGATCAGACTGTACCTGATGTTCAGATGTTTTTCTTTCACA

>In-frame_ENST00000341285_ENST00000288723_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(amino acids)=247AA_start in transcript=53_stop in transcript=796
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------
>In-frame_ENST00000341285_ENST00000338176_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(transcript)=1706nt_BP=209nt
ACCGGGCGCGCGCGCCGACGGGGCGGGCGCATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGG
CCGCGGCTGCTGAGGCGGAGGCTGAGGCAGTGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGA
AGCAGCTGGTGGGGCTCTACTGCGACAAGACCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAG
GACTGGATTTCTTTTTGAGAAGGATAACATTGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAG
GCAAAATGTTGGATAAATATATCTATGGAGCACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAG
ATTGGTATACTGTGGTGAAGAAAGTGAGCGAGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATA
TGCGAACAATAAAACCTGAAAAACACTTACGGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTG
TCTTCCTGTGCTTTCAGAAAGTTGCTGCTGAAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGGGCCATTTCATTA
TTTTCATTTCATCAACTAATAGAGAATAATCGAGTGTGCTTTGTGGCTCTAAAAATAAAGAGGGTGGTGAAGGCAGATATTGTAAACTAC
AACCAGGAACCTATGTCAAGGACTGTTAACCCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCATTTTTCTTTTGTGTTGATAGTT
CTGGCTGCCCTTCACCTCTGGGTGGGCCCGAGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCTGTAGTTCAGTTAACACTTTACT
CCCAACTTGCTTCATCATTGCTATTGCCTCACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAACTTTGGGACCACACACTTTGAA
TTCAAAATGGAAAACCCATTCCCTGGAATTAGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTGTATGTCCTTGCTTCTTTTTTCA
TTGATGTAAATTTTTTTAACTTAATATGAAAACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCACAGCAATTTCATTCTCTTATCG
GAACTTGTATGTGTCAAAGTATACTTCAGAGTGCAAACATTAAGCAAGTAATATATTTTACCTACAGATACTTATGAAGACATTCTTTCG
CTATCGTGAGTAAAAGTATATAAAGCTGTTTCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAATATTTTTTCATTTTTTAAAAAA
GGGCCTAAATTGTTTATATTGTAGTTTGTAACTCACAAAGTAATATTTGATATTGTATTTTTATTACTGTATCGTTGTCGTTATGTATTG
TGTAATACTCAGGTTTGAAGGCTTTCTGAATTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTTCTCTTGCAAACTGCATAAGAGT

>In-frame_ENST00000341285_ENST00000338176_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(amino acids)=231AA_start in transcript=53_stop in transcript=748
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------
>In-frame_ENST00000412094_ENST00000330852_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(transcript)=1604nt_BP=179nt
ATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGGCCGCGGCTGCTGAGGCGGAGGCTGAGGCAG
TGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGAAGCAGCTGGTGGGGCTCTACTGCGACAAGA
CCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAGGACTGGATTTCTTTTTGAGAAGGATAACAT
TGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAGGCAAAATGTTGGATAAATATATCTATGGAG
CACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAGATTGGTATACTGTGGTGAAGAAAGTGAGCG
AGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATATGCGAACAATAAAACCTGAAAAACACTTAC
GGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTGTCTTCCTGTGCTTTCAGAAAGTTGCTGCTG
AAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGAGGGTGGTGAAGGCAGATATTGTAAACTACAACCAGGAACCTA
TGTCAAGGACTGTTAACCCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCATTTTTCTTTTGTGTTGATAGTTCTGGCTGCCCTTC
ACCTCTGGGTGGGCCCGAGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCTGTAGTTCAGTTAACACTTTACTCCCAACTTGCTTC
ATCATTGCTATTGCCTCACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAACTTTGGGACCACACACTTTGAATTCAAAATGGAAA
ACCCATTCCCTGGAATTAGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTGTATGTCCTTGCTTCTTTTTTCATTGATGTAAATTT
TTTTAACTTAATATGAAAACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCACAGCAATTTCATTCTCTTATCGGAACTTGTATGTG
TCAAAGTATACTTCAGAGTGCAAACATTAAGCAAGTAATATATTTTACCTACAGATACTTATGAAGACATTCTTTCGCTATCGTGAGTAA
AAGTATATAAAGCTGTTTCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAATATTTTTTCATTTTTTAAAAAAGGGCCTAAATTGT
TTATATTGTAGTTTGTAACTCACAAAGTAATATTTGATATTGTATTTTTATTACTGTATCGTTGTCGTTATGTATTGTGTAATACTCAGG
TTTGAAGGCTTTCTGAATTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTTCTCTTGCAAACTGCATAAGAGTACTCCCGAGAATG

>In-frame_ENST00000412094_ENST00000330852_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(amino acids)=248AA_start in transcript=23_stop in transcript=769
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------
>In-frame_ENST00000412094_ENST00000288723_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(transcript)=1699nt_BP=179nt
ATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGGCCGCGGCTGCTGAGGCGGAGGCTGAGGCAG
TGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGAAGCAGCTGGTGGGGCTCTACTGCGACAAGA
CCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAGGACTGGATTTCTTTTTGAGAAGGATAACAT
TGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAGGCAAAATGTTGGATAAATATATCTATGGAG
CACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAGATTGGTATACTGTGGTGAAGAAAGTGAGCG
AGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATATGCGAACAATAAAACCTGAAAAACACTTAC
GGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTGTCTTCCTGTGCTTTCAGAAAGTTGCTGCTG
AAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGCGTATTGTCAGGGCAGAAATAGTGAAGTACCCGGAAGAAGAAA
ATCAACATACCACCTCTACTCAGAGTAGAATCTGTTCAGTACAGTAGTGCAGAGGGTGGTGAAGGCAGATATTGTAAACTACAACCAGGA
ACCTATGTCAAGGACTGTTAACCCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCATTTTTCTTTTGTGTTGATAGTTCTGGCTGC
CCTTCACCTCTGGGTGGGCCCGAGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCTGTAGTTCAGTTAACACTTTACTCCCAACTT
GCTTCATCATTGCTATTGCCTCACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAACTTTGGGACCACACACTTTGAATTCAAAAT
GGAAAACCCATTCCCTGGAATTAGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTGTATGTCCTTGCTTCTTTTTTCATTGATGTA
AATTTTTTTAACTTAATATGAAAACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCACAGCAATTTCATTCTCTTATCGGAACTTGT
ATGTGTCAAAGTATACTTCAGAGTGCAAACATTAAGCAAGTAATATATTTTACCTACAGATACTTATGAAGACATTCTTTCGCTATCGTG
AGTAAAAGTATATAAAGCTGTTTCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAATATTTTTTCATTTTTTAAAAAAGGGCCTAA
ATTGTTTATATTGTAGTTTGTAACTCACAAAGTAATATTTGATATTGTATTTTTATTACTGTATCGTTGTCGTTATGTATTGTGTAATAC
TCAGGTTTGAAGGCTTTCTGAATTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTTCTCTTGCAAACTGCATAAGAGTACTCCCGA

>In-frame_ENST00000412094_ENST00000288723_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(amino acids)=247AA_start in transcript=23_stop in transcript=766
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------
>In-frame_ENST00000412094_ENST00000338176_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(transcript)=1676nt_BP=179nt
ATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGGCCGCGGCTGCTGAGGCGGAGGCTGAGGCAG
TGGCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGAAGCAGCTGGTGGGGCTCTACTGCGACAAGA
CCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAGGACTGGATTTCTTTTTGAGAAGGATAACAT
TGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAGGCAAAATGTTGGATAAATATATCTATGGAG
CACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAGATTGGTATACTGTGGTGAAGAAAGTGAGCG
AGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATATGCGAACAATAAAACCTGAAAAACACTTAC
GGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTGTCTTCCTGTGCTTTCAGAAAGTTGCTGCTG
AAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGGGCCATTTCATTATTTTCATTTCATCAACTAATAGAGAATAAT
CGAGTGTGCTTTGTGGCTCTAAAAATAAAGAGGGTGGTGAAGGCAGATATTGTAAACTACAACCAGGAACCTATGTCAAGGACTGTTAAC
CCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCATTTTTCTTTTGTGTTGATAGTTCTGGCTGCCCTTCACCTCTGGGTGGGCCCG
AGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCTGTAGTTCAGTTAACACTTTACTCCCAACTTGCTTCATCATTGCTATTGCCTC
ACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAACTTTGGGACCACACACTTTGAATTCAAAATGGAAAACCCATTCCCTGGAATT
AGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTGTATGTCCTTGCTTCTTTTTTCATTGATGTAAATTTTTTTAACTTAATATGAA
AACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCACAGCAATTTCATTCTCTTATCGGAACTTGTATGTGTCAAAGTATACTTCAGA
GTGCAAACATTAAGCAAGTAATATATTTTACCTACAGATACTTATGAAGACATTCTTTCGCTATCGTGAGTAAAAGTATATAAAGCTGTT
TCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAATATTTTTTCATTTTTTAAAAAAGGGCCTAAATTGTTTATATTGTAGTTTGTA
ACTCACAAAGTAATATTTGATATTGTATTTTTATTACTGTATCGTTGTCGTTATGTATTGTGTAATACTCAGGTTTGAAGGCTTTCTGAA
TTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTTCTCTTGCAAACTGCATAAGAGTACTCCCGAGAATGAGTTATGACATTGTGGA

>In-frame_ENST00000412094_ENST00000338176_TCGA-M7-A724_FBXL5_chr4_15656826_-_RAB28_chr4_13481150_length(amino acids)=231AA_start in transcript=23_stop in transcript=718
MPRGEGVYGEAAAAAAEAEAEAVAMAPFPEEVDVFTAPHWRMKQLVGLYCDKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVT
LQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FBXL5-RAB28


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FBXL5-RAB28


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FBXL5-RAB28


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneRAB28C3809299CONE-ROD DYSTROPHY 184CLINGEN;CTD_human;GENOMICS_ENGLAND
TgeneRAB28C3489532Cone-Rod Dystrophy 21ORPHANET