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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FOXK2-NARF (FusionGDB2 ID:31012)

Fusion Gene Summary for FOXK2-NARF

check button Fusion gene summary
Fusion gene informationFusion gene name: FOXK2-NARF
Fusion gene ID: 31012
HgeneTgene
Gene symbol

FOXK2

NARF

Gene ID

3607

51444

Gene nameforkhead box K2ring finger protein 138
SynonymsILF|ILF-1|ILF1|nGTBPHSD-4|NARF|STRIN|hNARF
Cytomap

17q25.3

18q12.1

Type of geneprotein-codingprotein-coding
Descriptionforkhead box protein K2FOXK1G/T-mismatch specific binding proteincellular transcription factor ILF-1interleukin enhancer-binding factor 1E3 ubiquitin-protein ligase RNF138NLK-associated RING finger proteinNemo-like kinase-associated RING finger proteinRING-type E3 ubiquitin transferase RNF138nemo-like kinase associated ring finger proteinring finger protein 138, E3 ubiquitin protein l
Modification date2020031320200313
UniProtAcc

Q01167

Q9UHQ1

Ensembl transtripts involved in fusion geneENST00000335255, ENST00000529652, 
ENST00000390006, ENST00000309794, 
ENST00000345415, ENST00000457415, 
ENST00000412079, ENST00000581743, 
Fusion gene scores* DoF score31 X 14 X 13=56429 X 13 X 9=1053
# samples 3414
** MAII scorelog2(34/5642*10)=-4.05260001444787
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1053*10)=-2.91100670408075
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FOXK2 [Title/Abstract] AND NARF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFOXK2(80478183)-NARF(80436676), # samples:2
FOXK2(80542064)-NARF(80441592), # samples:2
Anticipated loss of major functional domain due to fusion event.FOXK2-NARF seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
FOXK2-NARF seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFOXK2

GO:0045892

negative regulation of transcription, DNA-templated

20810654|25451922

HgeneFOXK2

GO:0045893

positive regulation of transcription, DNA-templated

22083952

HgeneFOXK2

GO:0045944

positive regulation of transcription by RNA polymerase II

9065434


check buttonFusion gene breakpoints across FOXK2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across NARF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1428FOXK2chr17

80478183

+NARFchr17

80436675

+
ChimerDB4OVTCGA-24-1428-01AFOXK2chr17

80478183

+NARFchr17

80436676

+
ChimerDB4OVTCGA-24-1428-01AFOXK2chr17

80478183

+NARFchr17

80436447

+
ChimerDB4STADTCGA-VQ-AA6D-01AFOXK2chr17

80478183

+NARFchr17

80441592

+
ChimerDB4STADTCGA-VQ-AA6D-01AFOXK2chr17

80478183

+NARFchr17

80443373

+
ChimerDB4UCECTCGA-AJ-A3IA-01AFOXK2chr17

80542064

+NARFchr17

80441592

+
ChimerDB4OVTCGA-24-1428-01AFOXK2chr17

80478183

-NARFchr17

80436676

+
ChimerDB4UCECTCGA-AJ-A3IA-01AFOXK2chr17

80542064

-NARFchr17

80441592

+


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Fusion Gene ORF analysis for FOXK2-NARF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000335255ENST00000390006FOXK2chr17

80478183

+NARFchr17

80436675

+
Frame-shiftENST00000335255ENST00000309794FOXK2chr17

80478183

+NARFchr17

80436675

+
Frame-shiftENST00000335255ENST00000345415FOXK2chr17

80478183

+NARFchr17

80436675

+
Frame-shiftENST00000335255ENST00000457415FOXK2chr17

80478183

+NARFchr17

80436675

+
Frame-shiftENST00000335255ENST00000412079FOXK2chr17

80478183

+NARFchr17

80436675

+
5CDS-3UTRENST00000335255ENST00000581743FOXK2chr17

80478183

+NARFchr17

80436675

+
intron-3CDSENST00000529652ENST00000390006FOXK2chr17

80478183

+NARFchr17

80436675

+
intron-3CDSENST00000529652ENST00000309794FOXK2chr17

80478183

+NARFchr17

80436675

+
intron-3CDSENST00000529652ENST00000345415FOXK2chr17

80478183

+NARFchr17

80436675

+
intron-3CDSENST00000529652ENST00000457415FOXK2chr17

80478183

+NARFchr17

80436675

+
intron-3CDSENST00000529652ENST00000412079FOXK2chr17

80478183

+NARFchr17

80436675

+
intron-3UTRENST00000529652ENST00000581743FOXK2chr17

80478183

+NARFchr17

80436675

+
Frame-shiftENST00000335255ENST00000390006FOXK2chr17

80478183

+NARFchr17

80436676

+
Frame-shiftENST00000335255ENST00000309794FOXK2chr17

80478183

+NARFchr17

80436676

+
Frame-shiftENST00000335255ENST00000345415FOXK2chr17

80478183

+NARFchr17

80436676

+
Frame-shiftENST00000335255ENST00000457415FOXK2chr17

80478183

+NARFchr17

80436676

+
Frame-shiftENST00000335255ENST00000412079FOXK2chr17

80478183

+NARFchr17

80436676

+
5CDS-3UTRENST00000335255ENST00000581743FOXK2chr17

80478183

+NARFchr17

80436676

+
intron-3CDSENST00000529652ENST00000390006FOXK2chr17

80478183

+NARFchr17

80436676

+
intron-3CDSENST00000529652ENST00000309794FOXK2chr17

80478183

+NARFchr17

80436676

+
intron-3CDSENST00000529652ENST00000345415FOXK2chr17

80478183

+NARFchr17

80436676

+
intron-3CDSENST00000529652ENST00000457415FOXK2chr17

80478183

+NARFchr17

80436676

+
intron-3CDSENST00000529652ENST00000412079FOXK2chr17

80478183

+NARFchr17

80436676

+
intron-3UTRENST00000529652ENST00000581743FOXK2chr17

80478183

+NARFchr17

80436676

+
5CDS-intronENST00000335255ENST00000390006FOXK2chr17

80478183

+NARFchr17

80436447

+
5CDS-intronENST00000335255ENST00000309794FOXK2chr17

80478183

+NARFchr17

80436447

+
5CDS-intronENST00000335255ENST00000345415FOXK2chr17

80478183

+NARFchr17

80436447

+
5CDS-intronENST00000335255ENST00000457415FOXK2chr17

80478183

+NARFchr17

80436447

+
5CDS-intronENST00000335255ENST00000412079FOXK2chr17

80478183

+NARFchr17

80436447

+
5CDS-intronENST00000335255ENST00000581743FOXK2chr17

80478183

+NARFchr17

80436447

+
intron-intronENST00000529652ENST00000390006FOXK2chr17

80478183

+NARFchr17

80436447

+
intron-intronENST00000529652ENST00000309794FOXK2chr17

80478183

+NARFchr17

80436447

+
intron-intronENST00000529652ENST00000345415FOXK2chr17

80478183

+NARFchr17

80436447

+
intron-intronENST00000529652ENST00000457415FOXK2chr17

80478183

+NARFchr17

80436447

+
intron-intronENST00000529652ENST00000412079FOXK2chr17

80478183

+NARFchr17

80436447

+
intron-intronENST00000529652ENST00000581743FOXK2chr17

80478183

+NARFchr17

80436447

+
Frame-shiftENST00000335255ENST00000390006FOXK2chr17

80478183

+NARFchr17

80441592

+
Frame-shiftENST00000335255ENST00000309794FOXK2chr17

80478183

+NARFchr17

80441592

+
Frame-shiftENST00000335255ENST00000345415FOXK2chr17

80478183

+NARFchr17

80441592

+
Frame-shiftENST00000335255ENST00000457415FOXK2chr17

80478183

+NARFchr17

80441592

+
Frame-shiftENST00000335255ENST00000412079FOXK2chr17

80478183

+NARFchr17

80441592

+
5CDS-intronENST00000335255ENST00000581743FOXK2chr17

80478183

+NARFchr17

80441592

+
intron-3CDSENST00000529652ENST00000390006FOXK2chr17

80478183

+NARFchr17

80441592

+
intron-3CDSENST00000529652ENST00000309794FOXK2chr17

80478183

+NARFchr17

80441592

+
intron-3CDSENST00000529652ENST00000345415FOXK2chr17

80478183

+NARFchr17

80441592

+
intron-3CDSENST00000529652ENST00000457415FOXK2chr17

80478183

+NARFchr17

80441592

+
intron-3CDSENST00000529652ENST00000412079FOXK2chr17

80478183

+NARFchr17

80441592

+
intron-intronENST00000529652ENST00000581743FOXK2chr17

80478183

+NARFchr17

80441592

+
In-frameENST00000335255ENST00000390006FOXK2chr17

80478183

+NARFchr17

80443373

+
In-frameENST00000335255ENST00000309794FOXK2chr17

80478183

+NARFchr17

80443373

+
In-frameENST00000335255ENST00000345415FOXK2chr17

80478183

+NARFchr17

80443373

+
In-frameENST00000335255ENST00000457415FOXK2chr17

80478183

+NARFchr17

80443373

+
5CDS-intronENST00000335255ENST00000412079FOXK2chr17

80478183

+NARFchr17

80443373

+
5CDS-intronENST00000335255ENST00000581743FOXK2chr17

80478183

+NARFchr17

80443373

+
intron-3CDSENST00000529652ENST00000390006FOXK2chr17

80478183

+NARFchr17

80443373

+
intron-3CDSENST00000529652ENST00000309794FOXK2chr17

80478183

+NARFchr17

80443373

+
intron-3CDSENST00000529652ENST00000345415FOXK2chr17

80478183

+NARFchr17

80443373

+
intron-3CDSENST00000529652ENST00000457415FOXK2chr17

80478183

+NARFchr17

80443373

+
intron-intronENST00000529652ENST00000412079FOXK2chr17

80478183

+NARFchr17

80443373

+
intron-intronENST00000529652ENST00000581743FOXK2chr17

80478183

+NARFchr17

80443373

+
In-frameENST00000335255ENST00000390006FOXK2chr17

80542064

+NARFchr17

80441592

+
In-frameENST00000335255ENST00000309794FOXK2chr17

80542064

+NARFchr17

80441592

+
In-frameENST00000335255ENST00000345415FOXK2chr17

80542064

+NARFchr17

80441592

+
In-frameENST00000335255ENST00000457415FOXK2chr17

80542064

+NARFchr17

80441592

+
Frame-shiftENST00000335255ENST00000412079FOXK2chr17

80542064

+NARFchr17

80441592

+
5CDS-intronENST00000335255ENST00000581743FOXK2chr17

80542064

+NARFchr17

80441592

+
intron-3CDSENST00000529652ENST00000390006FOXK2chr17

80542064

+NARFchr17

80441592

+
intron-3CDSENST00000529652ENST00000309794FOXK2chr17

80542064

+NARFchr17

80441592

+
intron-3CDSENST00000529652ENST00000345415FOXK2chr17

80542064

+NARFchr17

80441592

+
intron-3CDSENST00000529652ENST00000457415FOXK2chr17

80542064

+NARFchr17

80441592

+
intron-3CDSENST00000529652ENST00000412079FOXK2chr17

80542064

+NARFchr17

80441592

+
intron-intronENST00000529652ENST00000581743FOXK2chr17

80542064

+NARFchr17

80441592

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000335255FOXK2chr1780542064+ENST00000390006NARFchr1780441592+215314531112054647
ENST00000335255FOXK2chr1780542064+ENST00000309794NARFchr1780441592+443514531112054647
ENST00000335255FOXK2chr1780542064+ENST00000345415NARFchr1780441592+216014531112054647
ENST00000335255FOXK2chr1780542064+ENST00000457415NARFchr1780441592+211314531112054647

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000335255ENST00000390006FOXK2chr1780542064+NARFchr1780441592+0.0122127240.9877873
ENST00000335255ENST00000309794FOXK2chr1780542064+NARFchr1780441592+0.0042392770.99576074
ENST00000335255ENST00000345415FOXK2chr1780542064+NARFchr1780441592+0.0121155230.98788446
ENST00000335255ENST00000457415FOXK2chr1780542064+NARFchr1780441592+0.0138832780.9861167

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Fusion Genomic Features for FOXK2-NARF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FOXK2chr1780542064+NARFchr1780441591+1.52E-050.99998474
FOXK2chr1780478183+NARFchr1780436675+2.69E-101
FOXK2chr1780478183+NARFchr1780436675+2.69E-101
FOXK2chr1780478183+NARFchr1780436446+1.85E-121
FOXK2chr1780478183+NARFchr1780441591+9.12E-131
FOXK2chr1780478183+NARFchr1780443372+1.85E-101
FOXK2chr1780542064+NARFchr1780441591+1.52E-050.99998474
FOXK2chr1780478183+NARFchr1780436675+2.69E-101
FOXK2chr1780478183+NARFchr1780436675+2.69E-101
FOXK2chr1780478183+NARFchr1780436446+1.85E-121
FOXK2chr1780478183+NARFchr1780441591+9.12E-131
FOXK2chr1780478183+NARFchr1780443372+1.85E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FOXK2-NARF


check button Go to

FGviewer for the breakpoints of chr17:80478183-chr17:80443373

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FOXK2

Q01167

NARF

Q9UHQ1

FUNCTION: Transcriptional regulator involved in different processes such as glucose metabolism, aerobic glycolysis and autophagy (By similarity). Recognizes and binds the forkhead DNA sequence motif (5'-GTAAACA-3') and can both act as a transcription activator or repressor, depending on the context (PubMed:22083952, PubMed:25451922). Together with FOXK1, acts as a key regulator of metabolic reprogramming towards aerobic glycolysis, a process in which glucose is converted to lactate in the presence of oxygen (By similarity). Acts by promoting expression of enzymes for glycolysis (such as hexokinase-2 (HK2), phosphofructokinase, pyruvate kinase (PKLR) and lactate dehydrogenase), while suppressing further oxidation of pyruvate in the mitochondria by up-regulating pyruvate dehydrogenase kinases PDK1 and PDK4 (By similarity). Probably plays a role in gluconeogenesis during overnight fasting, when lactate from white adipose tissue and muscle is the main substrate (By similarity). Together with FOXK1, acts as a negative regulator of autophagy in skeletal muscle: in response to starvation, enters the nucleus, binds the promoters of autophagy genes and represses their expression, preventing proteolysis of skeletal muscle proteins (By similarity). In addition to the 5'-GTAAACA-3' DNA motif, also binds the 5'-TGANTCA-3' palindromic DNA motif, and co-associates with JUN/AP-1 to activate transcription (PubMed:22083952). Also able to bind to a minimal DNA heteroduplex containing a G/T-mismatch with 5'-TRT[G/T]NB-3' sequence (PubMed:20097901). Binds to NFAT-like motifs (purine-rich) in the IL2 promoter (PubMed:1339390). Positively regulates WNT/beta-catenin signaling by translocating DVL proteins into the nucleus (PubMed:25805136). Also binds to HIV-1 long terminal repeat. May be involved in both positive and negative regulation of important viral and cellular promoter elements (PubMed:1909027). {ECO:0000250|UniProtKB:Q3UCQ1, ECO:0000269|PubMed:1339390, ECO:0000269|PubMed:1909027, ECO:0000269|PubMed:20097901, ECO:0000269|PubMed:22083952, ECO:0000269|PubMed:25451922, ECO:0000269|PubMed:25805136}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFOXK2chr17:80478183chr17:80443373ENST00000335255+1910_93139.66666666666666661.0Compositional biasNote=Gly-rich
HgeneFOXK2chr17:80542064chr17:80441592ENST00000335255+6910_93426.3333333333333661.0Compositional biasNote=Gly-rich
HgeneFOXK2chr17:80542064chr17:80441592ENST00000335255+69258_353426.3333333333333661.0DNA bindingFork-head
HgeneFOXK2chr17:80478183chr17:80443373ENST00000335255+1954_128139.66666666666666661.0DomainFHA
HgeneFOXK2chr17:80542064chr17:80441592ENST00000335255+6954_128426.3333333333333661.0DomainFHA
HgeneFOXK2chr17:80542064chr17:80441592ENST00000335255+69300_318426.3333333333333661.0RegionDNA-binding%3B major groove
HgeneFOXK2chr17:80542064chr17:80441592ENST00000335255+69328_332426.3333333333333661.0RegionDNA-binding%3B minor groove
HgeneFOXK2chr17:80542064chr17:80441592ENST00000335255+69348_353426.3333333333333661.0RegionDNA-binding%3B minor groove

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFOXK2chr17:80478183chr17:80443373ENST00000335255+19258_353139.66666666666666661.0DNA bindingFork-head
HgeneFOXK2chr17:80478183chr17:80443373ENST00000335255+19300_318139.66666666666666661.0RegionDNA-binding%3B major groove
HgeneFOXK2chr17:80478183chr17:80443373ENST00000335255+19328_332139.66666666666666661.0RegionDNA-binding%3B minor groove
HgeneFOXK2chr17:80478183chr17:80443373ENST00000335255+19348_353139.66666666666666661.0RegionDNA-binding%3B minor groove


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Fusion Gene Sequence for FOXK2-NARF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000335255_ENST00000390006_TCGA-AJ-A3IA-01A_FOXK2_chr17_80542064_+_NARF_chr17_80441592_length(transcript)=2153nt_BP=1453nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTGTGCACATTCAGGTTCCCGAGCACAAACATCAAGATA
ACGTTCACTGCCCTGTCCAGCGAGAAGAGAGAGAAGCAGGAGGCGTCTGAGTCTCCAGTGAAGGCCGTACAGCCACACATCTCGCCCCTG
ACCATCAACATTCCAGACACCATGGCCCACCTCATCAGCCCTCTGCCCTCCCCCACGGGAACCATCAGCGCTGCAAACTCCTGCCCCTCC
AGCCCCCGGGGAGCGGGGTCTTCAGGGTACAAGGTGGGCCGAGTGATGCCATCTGACCTCAATTTAATGGCTGACAACTCACAGCCTGAA
AATGAAAAGGAAGCTTCAGGTGGAGACAGCCCGAAGGATGATTCAAAGCCGCCTTACTCCTACGCGCAGCTGATAGTTCAGGCGATTACG
ATGGCTCCCGACAAACAGCTCACCCTGAACGGGATTTATACACACATCACTAAAAATTATCCCTACTACAGGACTGCGGACAAGGGCTGG
CAGAATTCAATTCGCCACAATCTCTCTCTGAATCGTTATTTCATCAAAGTGCCGCGTTCCCAGGAAGAACCAGGCAAAGGCTCGTTCTGG
AGGATAGACCCAGCCTCTGAAAGCAAATTAATAGAACAGGCTTTTAGGAAACGACGGCCTAGGGGCGTGCCCTGCTTTAGAACCCCTCTG
GGACCGCTCTCTTCTAGGAGTGCCCCAGCCTCTCCCAATCACGCGGGAGTGCTGTCTGCTCACTCTAGTGGCGCCCAGACCCCTGAGAGC
CTGTCGAGGGAAGGTTCGCCGGCCCCCCTGGAGCCTGAGCCTGGCGCTGCACAGCCCAAACTCGCTGTCATCCAGGAAGCCCGGTTTGCC
CAGAGCGCCCCAGGTGAAATTGCTCAAATAATGGAGCAAGGTGACCTCTCAGTGAGAGATGCTGCCGTCGACACTCTGTTTGGAGACTTG
AAGGAGGACAAAGTGACGCGTCATGATGGAGCCAGCTCAGACGGGCACCTGGCACACATCTTCAGACATGCGGCCAAGGAGCTGTTCAAC
GAGGATGTGGAGGAGGTCACTTACCGAGCCCTGAGAAACAAAGACTTCCAAGAGGTCACCCTTGAGAAGAACGGAGAGGTGGTGTTACGC
TTTGCTGCAGCCTATGGCTTTCGAAACATCCAGAACATGATCCTGAAGCTTAAGAAGGGCAAGTTCCCATTCCACTTTGTGGAGGTCCTC
GCCTGTGCTGGAGGATGCTTAAATGGCAGAGGCCAAGCCCAGACTCCAGACGGACATGCGGATAAGGCCCTGCTGCGGCAGATGGAAGGC
ATTTACGCTGACATCCCTGTGCGGCGTCCGGAGTCCAGTGCACACGTGCAGGAGCTGTACCAGGAGTGGCTGGAGGGGATCAACTCCCCC
AAGGCCCGAGAGGTGCTGCATACCACGTACCAGAGCCAGGAGCGTGGCACACACAGCCTGGACATCAAGTGGTGAAGTCAGGCCAGGGCC

>In-frame_ENST00000335255_ENST00000390006_TCGA-AJ-A3IA-01A_FOXK2_chr17_80542064_+_NARF_chr17_80441592_length(amino acids)=647AA_start in transcript=111_stop in transcript=2054
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSS
EKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASG
GDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASE
SKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGEI
AQIMEQGDLSVRDAAVDTLFGDLKEDKVTRHDGASSDGHLAHIFRHAAKELFNEDVEEVTYRALRNKDFQEVTLEKNGEVVLRFAAAYGF
RNIQNMILKLKKGKFPFHFVEVLACAGGCLNGRGQAQTPDGHADKALLRQMEGIYADIPVRRPESSAHVQELYQEWLEGINSPKAREVLH

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000309794_TCGA-AJ-A3IA-01A_FOXK2_chr17_80542064_+_NARF_chr17_80441592_length(transcript)=4435nt_BP=1453nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTGTGCACATTCAGGTTCCCGAGCACAAACATCAAGATA
ACGTTCACTGCCCTGTCCAGCGAGAAGAGAGAGAAGCAGGAGGCGTCTGAGTCTCCAGTGAAGGCCGTACAGCCACACATCTCGCCCCTG
ACCATCAACATTCCAGACACCATGGCCCACCTCATCAGCCCTCTGCCCTCCCCCACGGGAACCATCAGCGCTGCAAACTCCTGCCCCTCC
AGCCCCCGGGGAGCGGGGTCTTCAGGGTACAAGGTGGGCCGAGTGATGCCATCTGACCTCAATTTAATGGCTGACAACTCACAGCCTGAA
AATGAAAAGGAAGCTTCAGGTGGAGACAGCCCGAAGGATGATTCAAAGCCGCCTTACTCCTACGCGCAGCTGATAGTTCAGGCGATTACG
ATGGCTCCCGACAAACAGCTCACCCTGAACGGGATTTATACACACATCACTAAAAATTATCCCTACTACAGGACTGCGGACAAGGGCTGG
CAGAATTCAATTCGCCACAATCTCTCTCTGAATCGTTATTTCATCAAAGTGCCGCGTTCCCAGGAAGAACCAGGCAAAGGCTCGTTCTGG
AGGATAGACCCAGCCTCTGAAAGCAAATTAATAGAACAGGCTTTTAGGAAACGACGGCCTAGGGGCGTGCCCTGCTTTAGAACCCCTCTG
GGACCGCTCTCTTCTAGGAGTGCCCCAGCCTCTCCCAATCACGCGGGAGTGCTGTCTGCTCACTCTAGTGGCGCCCAGACCCCTGAGAGC
CTGTCGAGGGAAGGTTCGCCGGCCCCCCTGGAGCCTGAGCCTGGCGCTGCACAGCCCAAACTCGCTGTCATCCAGGAAGCCCGGTTTGCC
CAGAGCGCCCCAGGTGAAATTGCTCAAATAATGGAGCAAGGTGACCTCTCAGTGAGAGATGCTGCCGTCGACACTCTGTTTGGAGACTTG
AAGGAGGACAAAGTGACGCGTCATGATGGAGCCAGCTCAGACGGGCACCTGGCACACATCTTCAGACATGCGGCCAAGGAGCTGTTCAAC
GAGGATGTGGAGGAGGTCACTTACCGAGCCCTGAGAAACAAAGACTTCCAAGAGGTCACCCTTGAGAAGAACGGAGAGGTGGTGTTACGC
TTTGCTGCAGCCTATGGCTTTCGAAACATCCAGAACATGATCCTGAAGCTTAAGAAGGGCAAGTTCCCATTCCACTTTGTGGAGGTCCTC
GCCTGTGCTGGAGGATGCTTAAATGGCAGAGGCCAAGCCCAGACTCCAGACGGACATGCGGATAAGGCCCTGCTGCGGCAGATGGAAGGC
ATTTACGCTGACATCCCTGTGCGGCGTCCGGAGTCCAGTGCACACGTGCAGGAGCTGTACCAGGAGTGGCTGGAGGGGATCAACTCCCCC
AAGGCCCGAGAGGTGCTGCATACCACGTACCAGAGCCAGGAGCGTGGCACACACAGCCTGGACATCAAGTGGTGAAGTCAGGCCAGGGCC
TTCCAGCTGCTCTTGGGGCCAGAGCCAAGAGCCTCTCAGTAGAGGGAGGGGCTGCCCTGAGTGGAGTATTAAAGACACTTAAGAAAACCG
CTCAATGGATTACTTTGGTTTCTCCGAGTTCCCTGCTACCCCGTTTATTGGAGGCCCCTCAGGCAGTTTCATGTGGTGCTATCTTCATAA
TAGGTGTGGGATTGGAACTTTTTTTTTCTTTTTTTTTTTTTGAGACGGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAATGGCGCAATC
TCAGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTCTTGCCCCAGCCTCCCGAGTAGCTGGGACTAACGCGCACACCACCATG
CCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACTATGTTGGCCAGGCTGGTATTGAATTCCTGACCTCCTGATCCACCCGCC
TTGGCCTCCCAAAGTGCCAGGACTGCAGGCATGAGCCACCGTGCCTGGCAGATTGGAACGTTTTAACATGAGAGGAGCACTTCCCCAATT
TATCCCTTCATCCTAAGATTGTGAAAAAGTCCCAAAGAGTGGGAATGGAGACAGACTACTGTATTTTAGGTTTAAAAAGAAAAATCCAGA
AAGTGTCCTGTGAAGAGCTAGGACCCCCAGAGGTTCTAATGCACATGACTTGAAGGTGATTTGATGTGGGAGTGAGGGCAGAGGGTGGGG
TGGCTGTGCCTGTGGACTCCTGTGGCCCTGGGGTTGTTAGGGCAGGCAGTCCACAGTCCCAGATCCCTGCCCATTTTGGCTCTTTCTTTT
ACCCACTCATATTTTCCTTGAAAATGTTTTTGCCAGAACATTAATAACTGTCAGCCTTTTAGAATCAGGAGACTTACGTACAAATCTGGA
TTTTCAGCTTTTCTTAGAAAAACTGTAGTTTCTGACAACAGTAGGCCCCATTCCTCACAGCCAGTCACCACCCTCCTCCCATTCCTCACA
GCCAGTCACCACCCTCCTGGACCATACTCGGCCCTGGGCCATTCCTCACAGCCAGTCACCACCCTCCTCCCATTCCTCACAGCCAGTCAC
CACCCTCCTGGACCACACTCGGCCCTGGGCCATTCCTCACAGCCAGTCACCACCCTCCTGGACCATACTCAGGGCCCTGGAGGCCTGGCA
ACCCAGGCCCCAACTCAAACTTGTACATTCAGTCTTTCAGTCGGACTCGCACTGGGGCAAGGGTGACAGACACGAGAATGGAAAATTGAG
AAGGCTGCCCGCACCAGCTGGGTGGGTGCAGGGGGCCCCAGCTCATCATCAGCACTGTCGTGGGGTGGGAGTCGGGGGTAAAGGTTCCGT
CTGACCCTGAGGGGTTGAGGATATTCAGGTGGTCCAGCCTCCCGCAGAAGACTTCCCTGTCACCCTTGGCAGACAGGTTTCTTCTCACAC
GGCCCTGGCCCATCCACTCGCCATGAAGCCCTCTGTGCTCAGGGTGATGGAGCCCCCTCCATTCTGGCACTGCACTGTGGGCATGAGCTT
GCCTTAAAAAGAAAGGAGAGGCCAGGCACGGTGGCTCGTGCCCTATAATCCCAGCACACTGGGAGGCCAAGGTGGGAGGATTGCTGGAGT
CCAGGAGTTTCTACATGGGAGACTCTGTCTCTACAAATTTTTTTTTTTTTTTTGAGACAGAGTCTCACTTTGTCACCCAGGCTGGAGTTC
AGTGGCGTGATCTCGGCTCACAGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCTGGAGTAGCTGGGATTACAGGC
GCGCGCCACCGCGCCTGGCTAATTGTATTCTTAGTTGAGACGGGTTTCGCCATGTTGATCGGGCCGGTCAGGCTGGAATTTCTGACCTCA
GGTGATCCAACCACCTCAGCCTCCCAAAATGCTGGGATTACAGGCGTGAGCCACTGCACCTGGCAAAAAATTTTTTTTTAAAAAGGAGAA
AGCAGTTTAACCACAAACAGTGAAACAGAGCTGGCAGACGCCTGAAACTCCATGGAACCATGCAGCTGTACCCTAGGGCTCCTCCCAGGA
AAAGAGAGATGTCAACGTGGCCCAAGGTGTCCTGAAGCACTGGGATTGGATTAACTCGAGCGATGGCCTTCCCAGCCCTCCGTGCTGCAG
AGCCTCTGCTCGCTAGGCTGCCTTCATCTCACTCTGTGTGCTGTGCCTGTGCACCTGTCTTGTCAATAACTGCATATATTGTGTTGCGTT
GCCTGTCTTGCTGGATAACTGCATATATTGTGTTCAGTTGTGTATTTGTTTTGCTTTCAGTCTATATACAGTTGGGTTTCCAACCTCTGA

>In-frame_ENST00000335255_ENST00000309794_TCGA-AJ-A3IA-01A_FOXK2_chr17_80542064_+_NARF_chr17_80441592_length(amino acids)=647AA_start in transcript=111_stop in transcript=2054
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSS
EKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASG
GDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASE
SKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGEI
AQIMEQGDLSVRDAAVDTLFGDLKEDKVTRHDGASSDGHLAHIFRHAAKELFNEDVEEVTYRALRNKDFQEVTLEKNGEVVLRFAAAYGF
RNIQNMILKLKKGKFPFHFVEVLACAGGCLNGRGQAQTPDGHADKALLRQMEGIYADIPVRRPESSAHVQELYQEWLEGINSPKAREVLH

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000345415_TCGA-AJ-A3IA-01A_FOXK2_chr17_80542064_+_NARF_chr17_80441592_length(transcript)=2160nt_BP=1453nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTGTGCACATTCAGGTTCCCGAGCACAAACATCAAGATA
ACGTTCACTGCCCTGTCCAGCGAGAAGAGAGAGAAGCAGGAGGCGTCTGAGTCTCCAGTGAAGGCCGTACAGCCACACATCTCGCCCCTG
ACCATCAACATTCCAGACACCATGGCCCACCTCATCAGCCCTCTGCCCTCCCCCACGGGAACCATCAGCGCTGCAAACTCCTGCCCCTCC
AGCCCCCGGGGAGCGGGGTCTTCAGGGTACAAGGTGGGCCGAGTGATGCCATCTGACCTCAATTTAATGGCTGACAACTCACAGCCTGAA
AATGAAAAGGAAGCTTCAGGTGGAGACAGCCCGAAGGATGATTCAAAGCCGCCTTACTCCTACGCGCAGCTGATAGTTCAGGCGATTACG
ATGGCTCCCGACAAACAGCTCACCCTGAACGGGATTTATACACACATCACTAAAAATTATCCCTACTACAGGACTGCGGACAAGGGCTGG
CAGAATTCAATTCGCCACAATCTCTCTCTGAATCGTTATTTCATCAAAGTGCCGCGTTCCCAGGAAGAACCAGGCAAAGGCTCGTTCTGG
AGGATAGACCCAGCCTCTGAAAGCAAATTAATAGAACAGGCTTTTAGGAAACGACGGCCTAGGGGCGTGCCCTGCTTTAGAACCCCTCTG
GGACCGCTCTCTTCTAGGAGTGCCCCAGCCTCTCCCAATCACGCGGGAGTGCTGTCTGCTCACTCTAGTGGCGCCCAGACCCCTGAGAGC
CTGTCGAGGGAAGGTTCGCCGGCCCCCCTGGAGCCTGAGCCTGGCGCTGCACAGCCCAAACTCGCTGTCATCCAGGAAGCCCGGTTTGCC
CAGAGCGCCCCAGGTGAAATTGCTCAAATAATGGAGCAAGGTGACCTCTCAGTGAGAGATGCTGCCGTCGACACTCTGTTTGGAGACTTG
AAGGAGGACAAAGTGACGCGTCATGATGGAGCCAGCTCAGACGGGCACCTGGCACACATCTTCAGACATGCGGCCAAGGAGCTGTTCAAC
GAGGATGTGGAGGAGGTCACTTACCGAGCCCTGAGAAACAAAGACTTCCAAGAGGTCACCCTTGAGAAGAACGGAGAGGTGGTGTTACGC
TTTGCTGCAGCCTATGGCTTTCGAAACATCCAGAACATGATCCTGAAGCTTAAGAAGGGCAAGTTCCCATTCCACTTTGTGGAGGTCCTC
GCCTGTGCTGGAGGATGCTTAAATGGCAGAGGCCAAGCCCAGACTCCAGACGGACATGCGGATAAGGCCCTGCTGCGGCAGATGGAAGGC
ATTTACGCTGACATCCCTGTGCGGCGTCCGGAGTCCAGTGCACACGTGCAGGAGCTGTACCAGGAGTGGCTGGAGGGGATCAACTCCCCC
AAGGCCCGAGAGGTGCTGCATACCACGTACCAGAGCCAGGAGCGTGGCACACACAGCCTGGACATCAAGTGGTGAAGTCAGGCCAGGGCC
TTCCAGCTGCTCTTGGGGCCAGAGCCAAGAGCCTCTCAGTAGAGGGAGGGGCTGCCCTGAGTGGAGTATTAAAGACACTTAAGAAAACCG

>In-frame_ENST00000335255_ENST00000345415_TCGA-AJ-A3IA-01A_FOXK2_chr17_80542064_+_NARF_chr17_80441592_length(amino acids)=647AA_start in transcript=111_stop in transcript=2054
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSS
EKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASG
GDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASE
SKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGEI
AQIMEQGDLSVRDAAVDTLFGDLKEDKVTRHDGASSDGHLAHIFRHAAKELFNEDVEEVTYRALRNKDFQEVTLEKNGEVVLRFAAAYGF
RNIQNMILKLKKGKFPFHFVEVLACAGGCLNGRGQAQTPDGHADKALLRQMEGIYADIPVRRPESSAHVQELYQEWLEGINSPKAREVLH

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000457415_TCGA-AJ-A3IA-01A_FOXK2_chr17_80542064_+_NARF_chr17_80441592_length(transcript)=2113nt_BP=1453nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTGTGCACATTCAGGTTCCCGAGCACAAACATCAAGATA
ACGTTCACTGCCCTGTCCAGCGAGAAGAGAGAGAAGCAGGAGGCGTCTGAGTCTCCAGTGAAGGCCGTACAGCCACACATCTCGCCCCTG
ACCATCAACATTCCAGACACCATGGCCCACCTCATCAGCCCTCTGCCCTCCCCCACGGGAACCATCAGCGCTGCAAACTCCTGCCCCTCC
AGCCCCCGGGGAGCGGGGTCTTCAGGGTACAAGGTGGGCCGAGTGATGCCATCTGACCTCAATTTAATGGCTGACAACTCACAGCCTGAA
AATGAAAAGGAAGCTTCAGGTGGAGACAGCCCGAAGGATGATTCAAAGCCGCCTTACTCCTACGCGCAGCTGATAGTTCAGGCGATTACG
ATGGCTCCCGACAAACAGCTCACCCTGAACGGGATTTATACACACATCACTAAAAATTATCCCTACTACAGGACTGCGGACAAGGGCTGG
CAGAATTCAATTCGCCACAATCTCTCTCTGAATCGTTATTTCATCAAAGTGCCGCGTTCCCAGGAAGAACCAGGCAAAGGCTCGTTCTGG
AGGATAGACCCAGCCTCTGAAAGCAAATTAATAGAACAGGCTTTTAGGAAACGACGGCCTAGGGGCGTGCCCTGCTTTAGAACCCCTCTG
GGACCGCTCTCTTCTAGGAGTGCCCCAGCCTCTCCCAATCACGCGGGAGTGCTGTCTGCTCACTCTAGTGGCGCCCAGACCCCTGAGAGC
CTGTCGAGGGAAGGTTCGCCGGCCCCCCTGGAGCCTGAGCCTGGCGCTGCACAGCCCAAACTCGCTGTCATCCAGGAAGCCCGGTTTGCC
CAGAGCGCCCCAGGTGAAATTGCTCAAATAATGGAGCAAGGTGACCTCTCAGTGAGAGATGCTGCCGTCGACACTCTGTTTGGAGACTTG
AAGGAGGACAAAGTGACGCGTCATGATGGAGCCAGCTCAGACGGGCACCTGGCACACATCTTCAGACATGCGGCCAAGGAGCTGTTCAAC
GAGGATGTGGAGGAGGTCACTTACCGAGCCCTGAGAAACAAAGACTTCCAAGAGGTCACCCTTGAGAAGAACGGAGAGGTGGTGTTACGC
TTTGCTGCAGCCTATGGCTTTCGAAACATCCAGAACATGATCCTGAAGCTTAAGAAGGGCAAGTTCCCATTCCACTTTGTGGAGGTCCTC
GCCTGTGCTGGAGGATGCTTAAATGGCAGAGGCCAAGCCCAGACTCCAGACGGACATGCGGATAAGGCCCTGCTGCGGCAGATGGAAGGC
ATTTACGCTGACATCCCTGTGCGGCGTCCGGAGTCCAGTGCACACGTGCAGGAGCTGTACCAGGAGTGGCTGGAGGGGATCAACTCCCCC
AAGGCCCGAGAGGTGCTGCATACCACGTACCAGAGCCAGGAGCGTGGCACACACAGCCTGGACATCAAGTGGTGAAGTCAGGCCAGGGCC

>In-frame_ENST00000335255_ENST00000457415_TCGA-AJ-A3IA-01A_FOXK2_chr17_80542064_+_NARF_chr17_80441592_length(amino acids)=647AA_start in transcript=111_stop in transcript=2054
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSS
EKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASG
GDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASE
SKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGEI
AQIMEQGDLSVRDAAVDTLFGDLKEDKVTRHDGASSDGHLAHIFRHAAKELFNEDVEEVTYRALRNKDFQEVTLEKNGEVVLRFAAAYGF
RNIQNMILKLKKGKFPFHFVEVLACAGGCLNGRGQAQTPDGHADKALLRQMEGIYADIPVRRPESSAHVQELYQEWLEGINSPKAREVLH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FOXK2-NARF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FOXK2-NARF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FOXK2-NARF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource