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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FOXK2-TBCD (FusionGDB2 ID:31020)

Fusion Gene Summary for FOXK2-TBCD

check button Fusion gene summary
Fusion gene informationFusion gene name: FOXK2-TBCD
Fusion gene ID: 31020
HgeneTgene
Gene symbol

FOXK2

TBCD

Gene ID

3607

6904

Gene nameforkhead box K2tubulin folding cofactor D
SynonymsILF|ILF-1|ILF1|nGTBPPEBAT|SSD-1|tfcD
Cytomap

17q25.3

17q25.3

Type of geneprotein-codingprotein-coding
Descriptionforkhead box protein K2FOXK1G/T-mismatch specific binding proteincellular transcription factor ILF-1interleukin enhancer-binding factor 1tubulin-specific chaperone Dbeta-tubulin cofactor D
Modification date2020031320200313
UniProtAcc

Q01167

.
Ensembl transtripts involved in fusion geneENST00000335255, ENST00000529652, 
ENST00000355528, ENST00000397466, 
ENST00000539345, ENST00000576691, 
Fusion gene scores* DoF score31 X 14 X 13=564219 X 22 X 13=5434
# samples 3428
** MAII scorelog2(34/5642*10)=-4.05260001444787
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(28/5434*10)=-4.27851583327701
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FOXK2 [Title/Abstract] AND TBCD [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTBCD(80828256)-FOXK2(80521230), # samples:2
TBCD(80714091)-FOXK2(80544939), # samples:2
FOXK2(80529746)-TBCD(80755632), # samples:1
FOXK2(80478183)-TBCD(80772715), # samples:1
FOXK2(80478183)-TBCD(80842020), # samples:1
FOXK2(80526077)-TBCD(80897242), # samples:1
FOXK2(80478183)-TBCD(80772716), # samples:1
Anticipated loss of major functional domain due to fusion event.TBCD-FOXK2 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
TBCD-FOXK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
TBCD-FOXK2 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
TBCD-FOXK2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFOXK2

GO:0045892

negative regulation of transcription, DNA-templated

20810654|25451922

HgeneFOXK2

GO:0045893

positive regulation of transcription, DNA-templated

22083952

HgeneFOXK2

GO:0045944

positive regulation of transcription by RNA polymerase II

9065434

TgeneTBCD

GO:0006457

protein folding

20740604

TgeneTBCD

GO:0007021

tubulin complex assembly

28158450

TgeneTBCD

GO:0007023

post-chaperonin tubulin folding pathway

11847227

TgeneTBCD

GO:0031115

negative regulation of microtubule polymerization

10831612|20740604


check buttonFusion gene breakpoints across FOXK2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across TBCD (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-DK-A1A6FOXK2chr17

80529746

+TBCDchr17

80755632

+
ChimerDB4LUSCTCGA-66-2781FOXK2chr17

80478183

+TBCDchr17

80772715

+
ChimerDB4LUSCTCGA-66-2781FOXK2chr17

80478183

+TBCDchr17

80842020

+
ChimerDB4STADTCGA-BR-8382FOXK2chr17

80526077

+TBCDchr17

80897242

+
ChimerDB4LUSCTCGA-66-2781FOXK2chr17

80478183

+TBCDchr17

80772716

+


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Fusion Gene ORF analysis for FOXK2-TBCD

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000335255ENST00000355528FOXK2chr17

80529746

+TBCDchr17

80755632

+
5CDS-5UTRENST00000335255ENST00000397466FOXK2chr17

80529746

+TBCDchr17

80755632

+
5CDS-5UTRENST00000335255ENST00000539345FOXK2chr17

80529746

+TBCDchr17

80755632

+
5CDS-intronENST00000335255ENST00000576691FOXK2chr17

80529746

+TBCDchr17

80755632

+
intron-3CDSENST00000529652ENST00000355528FOXK2chr17

80529746

+TBCDchr17

80755632

+
intron-5UTRENST00000529652ENST00000397466FOXK2chr17

80529746

+TBCDchr17

80755632

+
intron-5UTRENST00000529652ENST00000539345FOXK2chr17

80529746

+TBCDchr17

80755632

+
intron-intronENST00000529652ENST00000576691FOXK2chr17

80529746

+TBCDchr17

80755632

+
In-frameENST00000335255ENST00000355528FOXK2chr17

80478183

+TBCDchr17

80772715

+
In-frameENST00000335255ENST00000397466FOXK2chr17

80478183

+TBCDchr17

80772715

+
In-frameENST00000335255ENST00000539345FOXK2chr17

80478183

+TBCDchr17

80772715

+
5CDS-intronENST00000335255ENST00000576691FOXK2chr17

80478183

+TBCDchr17

80772715

+
intron-3CDSENST00000529652ENST00000355528FOXK2chr17

80478183

+TBCDchr17

80772715

+
intron-3CDSENST00000529652ENST00000397466FOXK2chr17

80478183

+TBCDchr17

80772715

+
intron-3CDSENST00000529652ENST00000539345FOXK2chr17

80478183

+TBCDchr17

80772715

+
intron-intronENST00000529652ENST00000576691FOXK2chr17

80478183

+TBCDchr17

80772715

+
In-frameENST00000335255ENST00000355528FOXK2chr17

80478183

+TBCDchr17

80842020

+
In-frameENST00000335255ENST00000397466FOXK2chr17

80478183

+TBCDchr17

80842020

+
In-frameENST00000335255ENST00000539345FOXK2chr17

80478183

+TBCDchr17

80842020

+
5CDS-intronENST00000335255ENST00000576691FOXK2chr17

80478183

+TBCDchr17

80842020

+
intron-3CDSENST00000529652ENST00000355528FOXK2chr17

80478183

+TBCDchr17

80842020

+
intron-3CDSENST00000529652ENST00000397466FOXK2chr17

80478183

+TBCDchr17

80842020

+
intron-3CDSENST00000529652ENST00000539345FOXK2chr17

80478183

+TBCDchr17

80842020

+
intron-intronENST00000529652ENST00000576691FOXK2chr17

80478183

+TBCDchr17

80842020

+
In-frameENST00000335255ENST00000355528FOXK2chr17

80526077

+TBCDchr17

80897242

+
5CDS-intronENST00000335255ENST00000397466FOXK2chr17

80526077

+TBCDchr17

80897242

+
5CDS-intronENST00000335255ENST00000539345FOXK2chr17

80526077

+TBCDchr17

80897242

+
5CDS-3UTRENST00000335255ENST00000576691FOXK2chr17

80526077

+TBCDchr17

80897242

+
intron-3CDSENST00000529652ENST00000355528FOXK2chr17

80526077

+TBCDchr17

80897242

+
intron-intronENST00000529652ENST00000397466FOXK2chr17

80526077

+TBCDchr17

80897242

+
intron-intronENST00000529652ENST00000539345FOXK2chr17

80526077

+TBCDchr17

80897242

+
intron-3UTRENST00000529652ENST00000576691FOXK2chr17

80526077

+TBCDchr17

80897242

+
In-frameENST00000335255ENST00000355528FOXK2chr17

80478183

+TBCDchr17

80772716

+
In-frameENST00000335255ENST00000397466FOXK2chr17

80478183

+TBCDchr17

80772716

+
In-frameENST00000335255ENST00000539345FOXK2chr17

80478183

+TBCDchr17

80772716

+
5CDS-intronENST00000335255ENST00000576691FOXK2chr17

80478183

+TBCDchr17

80772716

+
intron-3CDSENST00000529652ENST00000355528FOXK2chr17

80478183

+TBCDchr17

80772716

+
intron-3CDSENST00000529652ENST00000397466FOXK2chr17

80478183

+TBCDchr17

80772716

+
intron-3CDSENST00000529652ENST00000539345FOXK2chr17

80478183

+TBCDchr17

80772716

+
intron-intronENST00000529652ENST00000576691FOXK2chr17

80478183

+TBCDchr17

80772716

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000335255FOXK2chr1780529746+ENST00000355528TBCDchr1780755632+4276108311138901259
ENST00000335255FOXK2chr1780478183+ENST00000355528TBCDchr1780772715+33345931112948945
ENST00000335255FOXK2chr1780478183+ENST00000397466TBCDchr1780772715+14645931111463450
ENST00000335255FOXK2chr1780478183+ENST00000539345TBCDchr1780772715+33095931113062983
ENST00000335255FOXK2chr1780478183+ENST00000355528TBCDchr1780842020+30825931112696861
ENST00000335255FOXK2chr1780478183+ENST00000397466TBCDchr1780842020+12125931111211366
ENST00000335255FOXK2chr1780478183+ENST00000539345TBCDchr1780842020+30575931112810899
ENST00000335255FOXK2chr1780526077+ENST00000355528TBCDchr1780897242+15319361111145344
ENST00000335255FOXK2chr1780478183+ENST00000355528TBCDchr1780772716+33345931112948945
ENST00000335255FOXK2chr1780478183+ENST00000397466TBCDchr1780772716+14645931111463450
ENST00000335255FOXK2chr1780478183+ENST00000539345TBCDchr1780772716+33095931113062983

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000335255ENST00000355528FOXK2chr1780529746+TBCDchr1780755632+0.0031079760.99689204
ENST00000335255ENST00000355528FOXK2chr1780478183+TBCDchr1780772715+0.002966510.9970335
ENST00000335255ENST00000397466FOXK2chr1780478183+TBCDchr1780772715+0.0614044140.9385956
ENST00000335255ENST00000539345FOXK2chr1780478183+TBCDchr1780772715+0.0023975020.9976025
ENST00000335255ENST00000355528FOXK2chr1780478183+TBCDchr1780842020+0.0048793250.9951207
ENST00000335255ENST00000397466FOXK2chr1780478183+TBCDchr1780842020+0.0497749520.9502251
ENST00000335255ENST00000539345FOXK2chr1780478183+TBCDchr1780842020+0.0039550160.99604493
ENST00000335255ENST00000355528FOXK2chr1780526077+TBCDchr1780897242+0.0192648840.9807351
ENST00000335255ENST00000355528FOXK2chr1780478183+TBCDchr1780772716+0.002966510.9970335
ENST00000335255ENST00000397466FOXK2chr1780478183+TBCDchr1780772716+0.0614044140.9385956
ENST00000335255ENST00000539345FOXK2chr1780478183+TBCDchr1780772716+0.0023975020.9976025

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Fusion Genomic Features for FOXK2-TBCD


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FOXK2chr1780529746+TBCDchr1780755632+0.171746150.82825387
FOXK2chr1780526077+TBCDchr1780897242+5.13E-070.9999995
FOXK2chr1780478183+TBCDchr1780772715+3.54E-091
FOXK2chr1780478183+TBCDchr1780842020+8.47E-091
FOXK2chr1780529746+TBCDchr1780755632+0.171746150.82825387
FOXK2chr1780526077+TBCDchr1780897242+5.13E-070.9999995
FOXK2chr1780478183+TBCDchr1780772715+3.54E-091
FOXK2chr1780478183+TBCDchr1780842020+8.47E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FOXK2-TBCD


check button Go to

FGviewer for the breakpoints of chr17:80529746-chr17:80755632

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FOXK2

Q01167

.
FUNCTION: Transcriptional regulator involved in different processes such as glucose metabolism, aerobic glycolysis and autophagy (By similarity). Recognizes and binds the forkhead DNA sequence motif (5'-GTAAACA-3') and can both act as a transcription activator or repressor, depending on the context (PubMed:22083952, PubMed:25451922). Together with FOXK1, acts as a key regulator of metabolic reprogramming towards aerobic glycolysis, a process in which glucose is converted to lactate in the presence of oxygen (By similarity). Acts by promoting expression of enzymes for glycolysis (such as hexokinase-2 (HK2), phosphofructokinase, pyruvate kinase (PKLR) and lactate dehydrogenase), while suppressing further oxidation of pyruvate in the mitochondria by up-regulating pyruvate dehydrogenase kinases PDK1 and PDK4 (By similarity). Probably plays a role in gluconeogenesis during overnight fasting, when lactate from white adipose tissue and muscle is the main substrate (By similarity). Together with FOXK1, acts as a negative regulator of autophagy in skeletal muscle: in response to starvation, enters the nucleus, binds the promoters of autophagy genes and represses their expression, preventing proteolysis of skeletal muscle proteins (By similarity). In addition to the 5'-GTAAACA-3' DNA motif, also binds the 5'-TGANTCA-3' palindromic DNA motif, and co-associates with JUN/AP-1 to activate transcription (PubMed:22083952). Also able to bind to a minimal DNA heteroduplex containing a G/T-mismatch with 5'-TRT[G/T]NB-3' sequence (PubMed:20097901). Binds to NFAT-like motifs (purine-rich) in the IL2 promoter (PubMed:1339390). Positively regulates WNT/beta-catenin signaling by translocating DVL proteins into the nucleus (PubMed:25805136). Also binds to HIV-1 long terminal repeat. May be involved in both positive and negative regulation of important viral and cellular promoter elements (PubMed:1909027). {ECO:0000250|UniProtKB:Q3UCQ1, ECO:0000269|PubMed:1339390, ECO:0000269|PubMed:1909027, ECO:0000269|PubMed:20097901, ECO:0000269|PubMed:22083952, ECO:0000269|PubMed:25451922, ECO:0000269|PubMed:25805136}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFOXK2chr17:80478183chr17:80772715ENST00000335255+1910_93139.66666666666666661.0Compositional biasNote=Gly-rich
HgeneFOXK2chr17:80478183chr17:80772716ENST00000335255+1910_93139.66666666666666661.0Compositional biasNote=Gly-rich
HgeneFOXK2chr17:80478183chr17:80842020ENST00000335255+1910_93139.66666666666666661.0Compositional biasNote=Gly-rich
HgeneFOXK2chr17:80526077chr17:80897242ENST00000335255+3910_93254.0661.0Compositional biasNote=Gly-rich
HgeneFOXK2chr17:80529746chr17:80755632ENST00000335255+4910_93303.0661.0Compositional biasNote=Gly-rich
HgeneFOXK2chr17:80478183chr17:80772715ENST00000335255+1954_128139.66666666666666661.0DomainFHA
HgeneFOXK2chr17:80478183chr17:80772716ENST00000335255+1954_128139.66666666666666661.0DomainFHA
HgeneFOXK2chr17:80478183chr17:80842020ENST00000335255+1954_128139.66666666666666661.0DomainFHA
HgeneFOXK2chr17:80526077chr17:80897242ENST00000335255+3954_128254.0661.0DomainFHA
HgeneFOXK2chr17:80529746chr17:80755632ENST00000335255+4954_128303.0661.0DomainFHA
TgeneTBCDchr17:80478183chr17:80772715ENST000003555281139557_594407.66666666666671193.0RepeatNote=HEAT 2
TgeneTBCDchr17:80478183chr17:80772715ENST000003555281139596_632407.66666666666671193.0RepeatNote=HEAT 3
TgeneTBCDchr17:80478183chr17:80772716ENST000003555281139557_594407.66666666666671193.0RepeatNote=HEAT 2
TgeneTBCDchr17:80478183chr17:80772716ENST000003555281139596_632407.66666666666671193.0RepeatNote=HEAT 3
TgeneTBCDchr17:80478183chr17:80842020ENST000003555281339557_594491.66666666666671193.0RepeatNote=HEAT 2
TgeneTBCDchr17:80478183chr17:80842020ENST000003555281339596_632491.66666666666671193.0RepeatNote=HEAT 3
TgeneTBCDchr17:80529746chr17:80755632ENST00000355528639361_399257.01193.0RepeatNote=HEAT 1
TgeneTBCDchr17:80529746chr17:80755632ENST00000355528639557_594257.01193.0RepeatNote=HEAT 2
TgeneTBCDchr17:80529746chr17:80755632ENST00000355528639596_632257.01193.0RepeatNote=HEAT 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFOXK2chr17:80478183chr17:80772715ENST00000335255+19258_353139.66666666666666661.0DNA bindingFork-head
HgeneFOXK2chr17:80478183chr17:80772716ENST00000335255+19258_353139.66666666666666661.0DNA bindingFork-head
HgeneFOXK2chr17:80478183chr17:80842020ENST00000335255+19258_353139.66666666666666661.0DNA bindingFork-head
HgeneFOXK2chr17:80526077chr17:80897242ENST00000335255+39258_353254.0661.0DNA bindingFork-head
HgeneFOXK2chr17:80529746chr17:80755632ENST00000335255+49258_353303.0661.0DNA bindingFork-head
HgeneFOXK2chr17:80478183chr17:80772715ENST00000335255+19300_318139.66666666666666661.0RegionDNA-binding%3B major groove
HgeneFOXK2chr17:80478183chr17:80772715ENST00000335255+19328_332139.66666666666666661.0RegionDNA-binding%3B minor groove
HgeneFOXK2chr17:80478183chr17:80772715ENST00000335255+19348_353139.66666666666666661.0RegionDNA-binding%3B minor groove
HgeneFOXK2chr17:80478183chr17:80772716ENST00000335255+19300_318139.66666666666666661.0RegionDNA-binding%3B major groove
HgeneFOXK2chr17:80478183chr17:80772716ENST00000335255+19328_332139.66666666666666661.0RegionDNA-binding%3B minor groove
HgeneFOXK2chr17:80478183chr17:80772716ENST00000335255+19348_353139.66666666666666661.0RegionDNA-binding%3B minor groove
HgeneFOXK2chr17:80478183chr17:80842020ENST00000335255+19300_318139.66666666666666661.0RegionDNA-binding%3B major groove
HgeneFOXK2chr17:80478183chr17:80842020ENST00000335255+19328_332139.66666666666666661.0RegionDNA-binding%3B minor groove
HgeneFOXK2chr17:80478183chr17:80842020ENST00000335255+19348_353139.66666666666666661.0RegionDNA-binding%3B minor groove
HgeneFOXK2chr17:80526077chr17:80897242ENST00000335255+39300_318254.0661.0RegionDNA-binding%3B major groove
HgeneFOXK2chr17:80526077chr17:80897242ENST00000335255+39328_332254.0661.0RegionDNA-binding%3B minor groove
HgeneFOXK2chr17:80526077chr17:80897242ENST00000335255+39348_353254.0661.0RegionDNA-binding%3B minor groove
HgeneFOXK2chr17:80529746chr17:80755632ENST00000335255+49300_318303.0661.0RegionDNA-binding%3B major groove
HgeneFOXK2chr17:80529746chr17:80755632ENST00000335255+49328_332303.0661.0RegionDNA-binding%3B minor groove
HgeneFOXK2chr17:80529746chr17:80755632ENST00000335255+49348_353303.0661.0RegionDNA-binding%3B minor groove
TgeneTBCDchr17:80478183chr17:80772715ENST000003555281139361_399407.66666666666671193.0RepeatNote=HEAT 1
TgeneTBCDchr17:80478183chr17:80772716ENST000003555281139361_399407.66666666666671193.0RepeatNote=HEAT 1
TgeneTBCDchr17:80478183chr17:80842020ENST000003555281339361_399491.66666666666671193.0RepeatNote=HEAT 1
TgeneTBCDchr17:80526077chr17:80897242ENST000003555283539361_3991123.01193.0RepeatNote=HEAT 1
TgeneTBCDchr17:80526077chr17:80897242ENST000003555283539557_5941123.01193.0RepeatNote=HEAT 2
TgeneTBCDchr17:80526077chr17:80897242ENST000003555283539596_6321123.01193.0RepeatNote=HEAT 3


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Fusion Gene Sequence for FOXK2-TBCD


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000335255_ENST00000355528_TCGA-DK-A1A6_FOXK2_chr17_80529746_+_TBCD_chr17_80755632_length(transcript)=4276nt_BP=1083nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTGTGCACATTCAGGTTCCCGAGCACAAACATCAAGATA
ACGTTCACTGCCCTGTCCAGCGAGAAGAGAGAGAAGCAGGAGGCGTCTGAGTCTCCAGTGAAGGCCGTACAGCCACACATCTCGCCCCTG
ACCATCAACATTCCAGACACCATGGCCCACCTCATCAGCCCTCTGCCCTCCCCCACGGGAACCATCAGCGCTGCAAACTCCTGCCCCTCC
AGCCCCCGGGGAGCGGGGTCTTCAGGGTACAAGGTGGGCCGAGTGATGCCATCTGACCTCAATTTAATGGCTGACAACTCACAGCCTGAA
AATGAAAAGGAAGCTTCAGGTGGAGACAGCCCGAAGGATGATTCAAAGCCGCCTTACTCCTACGCGCAGCTGATAGTTCAGGCGATTACG
ATGGCTCCCGACAAACAGCTCACCCTGAACGGGATTTATACACACATCACTAAAAATTATCCCTACTACAGGACTGCGGACAAGGGCTGG
CAGGCACAAATATTTAAACATGGAAAACGTGAAGACTGTTTGCCCTATGCTGCCACTGTCCTCAGGTGCCTCGATGGCTGCAGACTCCCT
GAGAGCAACCAGACCCTGCTGCGGAAGCTGGGGGTGAAGCTTGTGCAGCGACTGGGGCTGACATTCCTGAAGCCGAAGGTGGCAGCATGG
AGGTACCAGCGTGGCTGCCGATCTTTGGCTGCAAATCTGCAGCTCCTCACTCAGGGTCAGAGTGAGCAGAAGCCACTCATCCTGACCGAA
GATGACGACGAAGATGACGACGTCCCAGAGGGGGTGGAGCGTGTGATAGAGCAGCTGCTGGTCGGGCTGAAGGACAAGGACACGGTCGTG
CGGTGGTCTGCAGCCAAGGGCATCGGTAGGATGGCTGGCAGGCTTCCCAGAGCCCTGGCGGATGATGTGGTCGGGTCTGTGCTGGACTGC
TTCAGTTTCCAGGAGACTGACAAGGCGTGGCATGGGGGATGTCTGGCGCTGGCAGAGCTGGGCAGGAGAGGCCTGTTGCTGCCGTCTCGA
CTCGTGGATGTTGTCGCCGTGATCCTGAAGGCGCTGACCTACGACGAGAAGCGGGGTGCCTGCAGCGTGGGCACCAACGTCAGGGACGCC
GCCTGCTACGTGTGCTGGGCCTTCGCGCGTGCCTATGAGCCTCAGGAGCTGAAGCCCTTTGTGACTGCAATCTCGAGTGCACTGGTGATT
GCTGCGGTGTTTGACCGAGACATAAACTGCAGAAGAGCAGCCTCTGCCGCCTTCCAGGAGAATGTGGGGAGACAGGGCACTTTCCCTCAT
GGTATTGATATTTTGACCACAGCTGACTATTTTGCCGTCGGTAACAGATCCAACTGTTTCCTGGTTATAAGTGTGTTTATTGCCGGCTTT
CCTGAGTACACGCAGCCAATGATAGACCACCTGGTTACCATGAAGATCAGCCACTGGGATGGGGTCATCCGAGAGTTGGCTGCGAGGGCG
CTGCACAACCTGGCCCAGCAGGCACCCGAGTTCAGCGCCACGCAAGTCTTCCCGAGGCTGCTGTCCATGACACTGAGTCCAGATCTTCAC
ATGAGGCATGGGTCGATTCTCGCCTGCGCAGAAGTTGCTTACGCCTTGTACAAACTTGCAGCCCAAGAGAACAGGCCCGTCACGGACCAT
CTGGACGAGCAGGCAGTGCAGGGCCTGAAGCAGATTCACCAGCAGCTCTATGATCGTCAGTTATACAGGGGTCTGGGAGGACAGCTCATG
AGACAAGCAGTGTGTGTTTTAATAGAAAAGTTGTCACTTTCCAAAATGCCCTTTAGAGGTGACACCGTAATTGATGGTTGGCAATGGCTG
ATAAATGACACTTTGAGACATCTCCATCTCATCTCAAGTCACTCCCGCCAGCAGATGAAGGATGCAGCAGTCTCGGCCCTGGCTGCTCTA
TGCAGTGAATATTACATGAAGGAGCCGGGGGAGGCAGATCCCGCAATTCAGGAGGAGCTGATCACGCAGTACCTGGCTGAGCTTCGGAAC
CCCGAGGAGATGACTCGCTGTGGCTTCTCGTTGGCCTTGGGCGCCCTTCCAGGCTTCCTTCTGAAAGGCCGGCTCCAGCAGGTTCTCACA
GGTTTAAGAGCAGTTACCCACACTTCCCCCGAGGACGTAAGTTTTGCTGAGTCCAGGAGAGACGGCTTGAAGGCCATTGCGAGGATTTGC
CAGACTGTTGGTGTGAAAGCAGGAGCCCCAGACGAAGCTGTGTGCGGAGAGAATGTTTCCCAGATTTACTGTGCGCTGCTGGGCTGCATG
GACGACTACACCACGGACAGCAGAGGGGACGTGGGCACCTGGGTCCGCAAGGCCGCCATGACCAGTCTGATGGATCTGACACTTCTGCTG
GCTCGGAGCCAGCCTGAGCTGATCGAGGCCCATACCTGTGAGCGCATCATGTGCTGTGTGGCCCAGCAGGCCAGTGAGAAGATTGACCGT
TTCCGTGCTCACGCCGCCAGCGTGTTCCTGACGCTCCTGCACTTTGACAGCCCTCCCATCCCCCACGTGCCCCACCGAGGAGAACTGGAA
AAGCTGTTTCCCAGGTCCGATGTGGCCTCCGTGAACTGGAGTGCACCTTCCCAGGCCTTCCCACGCATCACCCAGCTCCTTGGGCTGCCC
ACCTACCGCTACCACGTCCTGCTGGGGCTAGTCGTGTCCCTGGGCGGCTTGACGGAGTCGACGATCCGGCACTCCACCCAGAGCCTCTTT
GAGTACATGAAGGGCATTCAGAGCGACCCGCAGGCCCTGGGCAGCTTCAGCGGGACCCTTCTGCAGATCTTTGAGGACAACCTTCTGAAT
GAGAGGGTGTCCGTGCCGCTGCTGAAGACGCTGGACCACGTGCTCACCCACGGCTGCTTCGACATCTTCACCACGGAGGAGGACCACCCC
TTTGCTGTGAAGTTGCTTGCGCTCTGTAAGAAAGAAATCAAGAATTCAAAAGATATCCAGAAGCTCCTGTCAGGCATCGCAGTGTTCTGC
GAGATGGTGCAGTTCCCCGGCGACGTGAGGAGGCAGGCCCTCCTGCAGCTGTGTCTGCTCCTCTGCCACCGTTTCCCGCTGATCCGGAAG
ACCACGGCCAGCCAGGTGTACGAGACATTGCTCACCTACAGTGACGTCGTGGGCGCGGATGTGCTGGACGAGGTGGTGACTGTGCTCAGT
GACACTGCGTGGGACGCGGAGCTTGCAGTGGTGAGAGAGCAGCGCAACCGTCTGTGTGACCTTCTGGGCGTACCCAGGCCCCAGCTGGTG
CCCCAGCCTGGTGCCTGCTGAAGCCAGTCCTGGAGCCCATACCTCACCCCTGCCTGGTGAGGATGTCTTGTTCCTGAGGGAGGCCGGTGT
GGAAAGCCTCGCACAGTGGTGCCTCCAGCTGTTGAAGGGTAGCGCTGGCCCTTGGAGGCTGGCACTAGCTGACAGCTTTTCCTCTCTGCA
CCTGCGCTCTGGTGACTTGGGGTGGACGCCTCTGCCTTCACTTGAACACAAATGTGCTTCCTATAAAATCATGTACCAAGAAGTTCCTGC
CTTTTGTCTCTGAGCCTGATGTGTGTAGGGGTGATGGAAAGGCTCACTGCCCAGGGGTCAGCCAGAGGGGAGGTGGGCTGCACTCCTCCT

>In-frame_ENST00000335255_ENST00000355528_TCGA-DK-A1A6_FOXK2_chr17_80529746_+_TBCD_chr17_80755632_length(amino acids)=1259AA_start in transcript=111_stop in transcript=3890
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSS
EKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASG
GDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQAQIFKHGKREDCLPYAATVLRCLDGCRLPESNQTLL
RKLGVKLVQRLGLTFLKPKVAAWRYQRGCRSLAANLQLLTQGQSEQKPLILTEDDDEDDDVPEGVERVIEQLLVGLKDKDTVVRWSAAKG
IGRMAGRLPRALADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWA
FARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPM
IDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQ
GLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMK
EPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALGALPGFLLKGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKA
GAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARSQPELIEAHTCERIMCCVAQQASEKIDRFRAHAAS
VFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQ
SDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQFPG

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000355528_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772715_length(transcript)=3334nt_BP=593nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTTTTCCAGGAGACTGACAAGGCGTGGCATGGGGGATGT
CTGGCGCTGGCAGAGCTGGGCAGGAGAGGCCTGTTGCTGCCGTCTCGACTCGTGGATGTTGTCGCCGTGATCCTGAAGGCGCTGACCTAC
GACGAGAAGCGGGGTGCCTGCAGCGTGGGCACCAACGTCAGGGACGCCGCCTGCTACGTGTGCTGGGCCTTCGCGCGTGCCTATGAGCCT
CAGGAGCTGAAGCCCTTTGTGACTGCAATCTCGAGTGCACTGGTGATTGCTGCGGTGTTTGACCGAGACATAAACTGCAGAAGAGCAGCC
TCTGCCGCCTTCCAGGAGAATGTGGGGAGACAGGGCACTTTCCCTCATGGTATTGATATTTTGACCACAGCTGACTATTTTGCCGTCGGT
AACAGATCCAACTGTTTCCTGGTTATAAGTGTGTTTATTGCCGGCTTTCCTGAGTACACGCAGCCAATGATAGACCACCTGGTTACCATG
AAGATCAGCCACTGGGATGGGGTCATCCGAGAGTTGGCTGCGAGGGCGCTGCACAACCTGGCCCAGCAGGCACCCGAGTTCAGCGCCACG
CAAGTCTTCCCGAGGCTGCTGTCCATGACACTGAGTCCAGATCTTCACATGAGGCATGGGTCGATTCTCGCCTGCGCAGAAGTTGCTTAC
GCCTTGTACAAACTTGCAGCCCAAGAGAACAGGCCCGTCACGGACCATCTGGACGAGCAGGCAGTGCAGGGCCTGAAGCAGATTCACCAG
CAGCTCTATGATCGTCAGTTATACAGGGGTCTGGGAGGACAGCTCATGAGACAAGCAGTGTGTGTTTTAATAGAAAAGTTGTCACTTTCC
AAAATGCCCTTTAGAGGTGACACCGTAATTGATGGTTGGCAATGGCTGATAAATGACACTTTGAGACATCTCCATCTCATCTCAAGTCAC
TCCCGCCAGCAGATGAAGGATGCAGCAGTCTCGGCCCTGGCTGCTCTATGCAGTGAATATTACATGAAGGAGCCGGGGGAGGCAGATCCC
GCAATTCAGGAGGAGCTGATCACGCAGTACCTGGCTGAGCTTCGGAACCCCGAGGAGATGACTCGCTGTGGCTTCTCGTTGGCCTTGGGC
GCCCTTCCAGGCTTCCTTCTGAAAGGCCGGCTCCAGCAGGTTCTCACAGGTTTAAGAGCAGTTACCCACACTTCCCCCGAGGACGTAAGT
TTTGCTGAGTCCAGGAGAGACGGCTTGAAGGCCATTGCGAGGATTTGCCAGACTGTTGGTGTGAAAGCAGGAGCCCCAGACGAAGCTGTG
TGCGGAGAGAATGTTTCCCAGATTTACTGTGCGCTGCTGGGCTGCATGGACGACTACACCACGGACAGCAGAGGGGACGTGGGCACCTGG
GTCCGCAAGGCCGCCATGACCAGTCTGATGGATCTGACACTTCTGCTGGCTCGGAGCCAGCCTGAGCTGATCGAGGCCCATACCTGTGAG
CGCATCATGTGCTGTGTGGCCCAGCAGGCCAGTGAGAAGATTGACCGTTTCCGTGCTCACGCCGCCAGCGTGTTCCTGACGCTCCTGCAC
TTTGACAGCCCTCCCATCCCCCACGTGCCCCACCGAGGAGAACTGGAAAAGCTGTTTCCCAGGTCCGATGTGGCCTCCGTGAACTGGAGT
GCACCTTCCCAGGCCTTCCCACGCATCACCCAGCTCCTTGGGCTGCCCACCTACCGCTACCACGTCCTGCTGGGGCTAGTCGTGTCCCTG
GGCGGCTTGACGGAGTCGACGATCCGGCACTCCACCCAGAGCCTCTTTGAGTACATGAAGGGCATTCAGAGCGACCCGCAGGCCCTGGGC
AGCTTCAGCGGGACCCTTCTGCAGATCTTTGAGGACAACCTTCTGAATGAGAGGGTGTCCGTGCCGCTGCTGAAGACGCTGGACCACGTG
CTCACCCACGGCTGCTTCGACATCTTCACCACGGAGGAGGACCACCCCTTTGCTGTGAAGTTGCTTGCGCTCTGTAAGAAAGAAATCAAG
AATTCAAAAGATATCCAGAAGCTCCTGTCAGGCATCGCAGTGTTCTGCGAGATGGTGCAGTTCCCCGGCGACGTGAGGAGGCAGGCCCTC
CTGCAGCTGTGTCTGCTCCTCTGCCACCGTTTCCCGCTGATCCGGAAGACCACGGCCAGCCAGGTGTACGAGACATTGCTCACCTACAGT
GACGTCGTGGGCGCGGATGTGCTGGACGAGGTGGTGACTGTGCTCAGTGACACTGCGTGGGACGCGGAGCTTGCAGTGGTGAGAGAGCAG
CGCAACCGTCTGTGTGACCTTCTGGGCGTACCCAGGCCCCAGCTGGTGCCCCAGCCTGGTGCCTGCTGAAGCCAGTCCTGGAGCCCATAC
CTCACCCCTGCCTGGTGAGGATGTCTTGTTCCTGAGGGAGGCCGGTGTGGAAAGCCTCGCACAGTGGTGCCTCCAGCTGTTGAAGGGTAG
CGCTGGCCCTTGGAGGCTGGCACTAGCTGACAGCTTTTCCTCTCTGCACCTGCGCTCTGGTGACTTGGGGTGGACGCCTCTGCCTTCACT
TGAACACAAATGTGCTTCCTATAAAATCATGTACCAAGAAGTTCCTGCCTTTTGTCTCTGAGCCTGATGTGTGTAGGGGTGATGGAAAGG
CTCACTGCCCAGGGGTCAGCCAGAGGGGAGGTGGGCTGCACTCCTCCTGCCTGGAGACCAGGCCCCCTTCTTGCCTGGTGCTGTCCCTGC

>In-frame_ENST00000335255_ENST00000355528_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772715_length(amino acids)=945AA_start in transcript=111_stop in transcript=2948
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVFQETDKAWHGGCLALAELG
RRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQEN
VGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLL
SMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGD
TVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALGALPGFLL
KGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMT
SLMDLTLLLARSQPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFP
RITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFD
IFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGADV

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000397466_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772715_length(transcript)=1464nt_BP=593nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTTTTCCAGGAGACTGACAAGGCGTGGCATGGGGGATGT
CTGGCGCTGGCAGAGCTGGGCAGGAGAGGCCTGTTGCTGCCGTCTCGACTCGTGGATGTTGTCGCCGTGATCCTGAAGGCGCTGACCTAC
GACGAGAAGCGGGGTGCCTGCAGCGTGGGCACCAACGTCAGGGACGCCGCCTGCTACGTGTGCTGGGCCTTCGCGCGTGCCTATGAGCCT
CAGGAGCTGAAGCCCTTTGTGACTGCAATCTCGAGTGCACTGGTGATTGCTGCGGTGTTTGACCGAGACATAAACTGCAGAAGAGCAGCC
TCTGCCGCCTTCCAGGAGAATGTGGGGAGACAGGGCACTTTCCCTCATGGTATTGATATTTTGACCACAGCTGACTATTTTGCCGTCGGT
AACAGATCCAACTGTTTCCTGGTTATAAGTGTGTTTATTGCCGGCTTTCCTGAGTACACGCAGCCAATGATAGACCACCTGGTTACCATG
AAGATCAGCCACTGGGATGGGGTCATCCGAGAGTTGGCTGCGAGGGCGCTGCACAACCTGGCCCAGCAGGCACCCGAGTTCAGCGCCACG
CAAGTCTTCCCGAGGCTGCTGTCCATGACACTGAGTCCAGATCTTCACATGAGGCATGGGTCGATTCTCGCCTGCGCAGAAGTTGCTTAC
GCCTTGTACAAACTTGCAGCCCAAGAGAACAGGCCCGTCACGGACCATCTGGACGAGCAGGCAGTGCAGGGCCTGAAGCAGATTCACCAG
CAGCCGTGCATCTGCAGCTGGGGTCTGATGTCTCCTGAAAGTAAAGCAGAATTTTGTGTGTGCGTCTGTCGGATTTCTCTGGGGAGACAG

>In-frame_ENST00000335255_ENST00000397466_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772715_length(amino acids)=450AA_start in transcript=111_stop in transcript=1463
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVFQETDKAWHGGCLALAELG
RRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQEN
VGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLL
SMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQPCICSWGLMSPESKAEFCVCVCRISLGRQCVHLSGL

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000539345_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772715_length(transcript)=3309nt_BP=593nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTTTTCCAGGAGACTGACAAGGCGTGGCATGGGGGATGT
CTGGCGCTGGCAGAGCTGGGCAGGAGAGGCCTGTTGCTGCCGTCTCGACTCGTGGATGTTGTCGCCGTGATCCTGAAGGCGCTGACCTAC
GACGAGAAGCGGGGTGCCTGCAGCGTGGGCACCAACGTCAGGGACGCCGCCTGCTACGTGTGCTGGGCCTTCGCGCGTGCCTATGAGCCT
CAGGAGCTGAAGCCCTTTGTGACTGCAATCTCGAGTGCACTGGTGATTGCTGCGGTGTTTGACCGAGACATAAACTGCAGAAGAGCAGCC
TCTGCCGCCTTCCAGGAGAATGTGGGGAGACAGGGCACTTTCCCTCATGGTATTGATATTTTGACCACAGCTGACTATTTTGCCGTCGGT
AACAGATCCAACTGTTTCCTGGTTATAAGTGTGTTTATTGCCGGCTTTCCTGAGTACACGCAGCCAATGATAGACCACCTGGTTACCATG
AAGATCAGCCACTGGGATGGGGTCATCCGAGAGTTGGCTGCGAGGGCGCTGCACAACCTGGCCCAGCAGGCACCCGAGTTCAGCGCCACG
CAAGTCTTCCCGAGGCTGCTGTCCATGACACTGAGTCCAGATCTTCACATGAGGCATGGGTCGATTCTCGCCTGCGCAGAAGTTGCTTAC
GCCTTGTACAAACTTGCAGCCCAAGAGAACAGGCCCGTCACGGACCATCTGGACGAGCAGGCAGTGCAGGGCCTGAAGCAGATTCACCAG
CAGCTCTATGATCGTCAGTTATACAGGGGTCTGGGAGGACAGCTCATGAGACAAGCAGTGTGTGTTTTAATAGAAAAGTTGTCACTTTCC
AAAATGCCCTTTAGAGGTGACACCGTAATTGATGGTTGGCAATGGCTGATAAATGACACTTTGAGACATCTCCATCTCATCTCAAGTCAC
TCCCGCCAGCAGATGAAGGATGCAGCAGTCTCGGCCCTGGCTGCTCTATGCAGTGAATATTACATGAAGGAGCCGGGGGAGGCAGATCCC
GCAATTCAGGAGGAGCTGATCACGCAGTACCTGGCTGAGCTTCGGAACCCCGAGGAGATGACTCGCTGTGGCTTCTCGTTGGCCTTGGGC
GCCCTTCCAGGCTTCCTTCTGAAAGGCCGGCTCCAGCAGGTTCTCACAGGTTTAAGAGCAGTTACCCACACTTCCCCCGAGGACGTAAGT
TTTGCTGAGTCCAGGAGAGACGGCTTGAAGGCCATTGCGAGGATTTGCCAGACTGTTGGTGTGAAAGCAGGAGCCCCAGACGAAGCTGTG
TGCGGAGAGAATGTTTCCCAGATTTACTGTGCGCTGCTGGGCTGCATGGACGACTACACCACGGACAGCAGAGGGGACGTGGGCACCTGG
GTCCGCAAGGCCGCCATGACCAGTCTGATGGATCTGACACTTCTGCTGGCTCGGAGCCAGCCTGAGCTGATCGAGGCCCATACCTGTGAG
CGCATCATGTGCTGTGTGGCCCAGCAGGCCAGTGAGAAGATTGACCGTTTCCGTGCTCACGCCGCCAGCGTGTTCCTGACGCTCCTGCAC
TTTGACAGCCCTCCCATCCCCCACGTGCCCCACCGAGGAGAACTGGAAAAGCTGTTTCCCAGGTCCGATGTGGCCTCCGTGAACTGGAGT
GCACCTTCCCAGGCCTTCCCACGCATCACCCAGCTCCTTGGGCTGCCCACCTACCGCTACCACGTCCTGCTGGGGCTAGTCGTGTCCCTG
GGCGGCTTGACGGAGTCGACGATCCGGCACTCCACCCAGAGCCTCTTTGAGTACATGAAGGGCATTCAGAGCGACCCGCAGGCCCTGGGC
AGCTTCAGCGGGACCCTTCTGCAGATCTTTGAGGACAACCTTCTGAATGAGAGGGTGTCCGTGCCGCTGCTGAAGACGCTGGACCACGTG
CTCACCCACGGCTGCTTCGACATCTTCACCACGGAGGAGGACCACCCCTTTGCTGTGAAGTTGCTTGCGCTCTGTAAGAAAGAAATCAAG
AATTCAAAAGATATCCAGAAGCTCCTGTCAGGCATCGCAGTTGACTTTCCAAGTGCGACACTCGTGTGTGTAGGCACAGTGCAGATGTAC
GCACACACACACCTCCGGCTTGGGGCCCCAGGCCCGCACTGTGCTCACGGATCTGCTCTGCCCAGGTTCTGCGAGATGGTGCAGTTCCCC
GGCGACGTGAGGAGGCAGGCCCTCCTGCAGCTGTGTCTGCTCCTCTGCCACCGTTTCCCGCTGATCCGGAAGACCACGGCCAGCCAGGTG
TACGAGACATTGCTCACCTACAGTGACGTCGTGGGCGCGGATGTGCTGGACGAGGTGGTGACTGTGCTCAGTGACACTGCGTGGGACGCG
GAGCTTGCAGTGGTGAGAGAGCAGCGCAACCGTCTGTGTGACCTTCTGGGCGTACCCAGGCCCCAGCTGGTGCCCCAGCCTGGTGCCTGC
TGAAGCCAGTCCTGGAGCCCATACCTCACCCCTGCCTGGTGAGGATGTCTTGTTCCTGAGGGAGGCCGGTGTGGAAAGCCTCGCACAGTG
GTGCCTCCAGCTGTTGAAGGGTAGCGCTGGCCCTTGGAGGCTGGCACTAGCTGACAGCTTTTCCTCTCTGCACCTGCGCTCTGGTGACTT

>In-frame_ENST00000335255_ENST00000539345_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772715_length(amino acids)=983AA_start in transcript=111_stop in transcript=3062
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVFQETDKAWHGGCLALAELG
RRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQEN
VGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLL
SMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGD
TVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALGALPGFLL
KGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMT
SLMDLTLLLARSQPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFP
RITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFD
IFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVDFPSATLVCVGTVQMYAHTHLRLGAPGPHCAHGSALPRFCEMVQFPGDVRRQA

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000355528_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80842020_length(transcript)=3082nt_BP=593nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTTGCACTGGTGATTGCTGCGGTGTTTGACCGAGACATA
AACTGCAGAAGAGCAGCCTCTGCCGCCTTCCAGGAGAATGTGGGGAGACAGGGCACTTTCCCTCATGGTATTGATATTTTGACCACAGCT
GACTATTTTGCCGTCGGTAACAGATCCAACTGTTTCCTGGTTATAAGTGTGTTTATTGCCGGCTTTCCTGAGTACACGCAGCCAATGATA
GACCACCTGGTTACCATGAAGATCAGCCACTGGGATGGGGTCATCCGAGAGTTGGCTGCGAGGGCGCTGCACAACCTGGCCCAGCAGGCA
CCCGAGTTCAGCGCCACGCAAGTCTTCCCGAGGCTGCTGTCCATGACACTGAGTCCAGATCTTCACATGAGGCATGGGTCGATTCTCGCC
TGCGCAGAAGTTGCTTACGCCTTGTACAAACTTGCAGCCCAAGAGAACAGGCCCGTCACGGACCATCTGGACGAGCAGGCAGTGCAGGGC
CTGAAGCAGATTCACCAGCAGCTCTATGATCGTCAGTTATACAGGGGTCTGGGAGGACAGCTCATGAGACAAGCAGTGTGTGTTTTAATA
GAAAAGTTGTCACTTTCCAAAATGCCCTTTAGAGGTGACACCGTAATTGATGGTTGGCAATGGCTGATAAATGACACTTTGAGACATCTC
CATCTCATCTCAAGTCACTCCCGCCAGCAGATGAAGGATGCAGCAGTCTCGGCCCTGGCTGCTCTATGCAGTGAATATTACATGAAGGAG
CCGGGGGAGGCAGATCCCGCAATTCAGGAGGAGCTGATCACGCAGTACCTGGCTGAGCTTCGGAACCCCGAGGAGATGACTCGCTGTGGC
TTCTCGTTGGCCTTGGGCGCCCTTCCAGGCTTCCTTCTGAAAGGCCGGCTCCAGCAGGTTCTCACAGGTTTAAGAGCAGTTACCCACACT
TCCCCCGAGGACGTAAGTTTTGCTGAGTCCAGGAGAGACGGCTTGAAGGCCATTGCGAGGATTTGCCAGACTGTTGGTGTGAAAGCAGGA
GCCCCAGACGAAGCTGTGTGCGGAGAGAATGTTTCCCAGATTTACTGTGCGCTGCTGGGCTGCATGGACGACTACACCACGGACAGCAGA
GGGGACGTGGGCACCTGGGTCCGCAAGGCCGCCATGACCAGTCTGATGGATCTGACACTTCTGCTGGCTCGGAGCCAGCCTGAGCTGATC
GAGGCCCATACCTGTGAGCGCATCATGTGCTGTGTGGCCCAGCAGGCCAGTGAGAAGATTGACCGTTTCCGTGCTCACGCCGCCAGCGTG
TTCCTGACGCTCCTGCACTTTGACAGCCCTCCCATCCCCCACGTGCCCCACCGAGGAGAACTGGAAAAGCTGTTTCCCAGGTCCGATGTG
GCCTCCGTGAACTGGAGTGCACCTTCCCAGGCCTTCCCACGCATCACCCAGCTCCTTGGGCTGCCCACCTACCGCTACCACGTCCTGCTG
GGGCTAGTCGTGTCCCTGGGCGGCTTGACGGAGTCGACGATCCGGCACTCCACCCAGAGCCTCTTTGAGTACATGAAGGGCATTCAGAGC
GACCCGCAGGCCCTGGGCAGCTTCAGCGGGACCCTTCTGCAGATCTTTGAGGACAACCTTCTGAATGAGAGGGTGTCCGTGCCGCTGCTG
AAGACGCTGGACCACGTGCTCACCCACGGCTGCTTCGACATCTTCACCACGGAGGAGGACCACCCCTTTGCTGTGAAGTTGCTTGCGCTC
TGTAAGAAAGAAATCAAGAATTCAAAAGATATCCAGAAGCTCCTGTCAGGCATCGCAGTGTTCTGCGAGATGGTGCAGTTCCCCGGCGAC
GTGAGGAGGCAGGCCCTCCTGCAGCTGTGTCTGCTCCTCTGCCACCGTTTCCCGCTGATCCGGAAGACCACGGCCAGCCAGGTGTACGAG
ACATTGCTCACCTACAGTGACGTCGTGGGCGCGGATGTGCTGGACGAGGTGGTGACTGTGCTCAGTGACACTGCGTGGGACGCGGAGCTT
GCAGTGGTGAGAGAGCAGCGCAACCGTCTGTGTGACCTTCTGGGCGTACCCAGGCCCCAGCTGGTGCCCCAGCCTGGTGCCTGCTGAAGC
CAGTCCTGGAGCCCATACCTCACCCCTGCCTGGTGAGGATGTCTTGTTCCTGAGGGAGGCCGGTGTGGAAAGCCTCGCACAGTGGTGCCT
CCAGCTGTTGAAGGGTAGCGCTGGCCCTTGGAGGCTGGCACTAGCTGACAGCTTTTCCTCTCTGCACCTGCGCTCTGGTGACTTGGGGTG
GACGCCTCTGCCTTCACTTGAACACAAATGTGCTTCCTATAAAATCATGTACCAAGAAGTTCCTGCCTTTTGTCTCTGAGCCTGATGTGT
GTAGGGGTGATGGAAAGGCTCACTGCCCAGGGGTCAGCCAGAGGGGAGGTGGGCTGCACTCCTCCTGCCTGGAGACCAGGCCCCCTTCTT

>In-frame_ENST00000335255_ENST00000355528_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80842020_length(amino acids)=861AA_start in transcript=111_stop in transcript=2696
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVALVIAAVFDRDINCRRAAS
AAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQ
VFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSK
MPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALGA
LPGFLLKGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWV
RKAAMTSLMDLTLLLARSQPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSA
PSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVL
THGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSD

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000397466_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80842020_length(transcript)=1212nt_BP=593nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTTGCACTGGTGATTGCTGCGGTGTTTGACCGAGACATA
AACTGCAGAAGAGCAGCCTCTGCCGCCTTCCAGGAGAATGTGGGGAGACAGGGCACTTTCCCTCATGGTATTGATATTTTGACCACAGCT
GACTATTTTGCCGTCGGTAACAGATCCAACTGTTTCCTGGTTATAAGTGTGTTTATTGCCGGCTTTCCTGAGTACACGCAGCCAATGATA
GACCACCTGGTTACCATGAAGATCAGCCACTGGGATGGGGTCATCCGAGAGTTGGCTGCGAGGGCGCTGCACAACCTGGCCCAGCAGGCA
CCCGAGTTCAGCGCCACGCAAGTCTTCCCGAGGCTGCTGTCCATGACACTGAGTCCAGATCTTCACATGAGGCATGGGTCGATTCTCGCC
TGCGCAGAAGTTGCTTACGCCTTGTACAAACTTGCAGCCCAAGAGAACAGGCCCGTCACGGACCATCTGGACGAGCAGGCAGTGCAGGGC
CTGAAGCAGATTCACCAGCAGCCGTGCATCTGCAGCTGGGGTCTGATGTCTCCTGAAAGTAAAGCAGAATTTTGTGTGTGCGTCTGTCGG

>In-frame_ENST00000335255_ENST00000397466_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80842020_length(amino acids)=366AA_start in transcript=111_stop in transcript=1211
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVALVIAAVFDRDINCRRAAS
AAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQ
VFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQPCICSWGLMSPESKAEFCVCVCRISLGRQC

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000539345_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80842020_length(transcript)=3057nt_BP=593nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTTGCACTGGTGATTGCTGCGGTGTTTGACCGAGACATA
AACTGCAGAAGAGCAGCCTCTGCCGCCTTCCAGGAGAATGTGGGGAGACAGGGCACTTTCCCTCATGGTATTGATATTTTGACCACAGCT
GACTATTTTGCCGTCGGTAACAGATCCAACTGTTTCCTGGTTATAAGTGTGTTTATTGCCGGCTTTCCTGAGTACACGCAGCCAATGATA
GACCACCTGGTTACCATGAAGATCAGCCACTGGGATGGGGTCATCCGAGAGTTGGCTGCGAGGGCGCTGCACAACCTGGCCCAGCAGGCA
CCCGAGTTCAGCGCCACGCAAGTCTTCCCGAGGCTGCTGTCCATGACACTGAGTCCAGATCTTCACATGAGGCATGGGTCGATTCTCGCC
TGCGCAGAAGTTGCTTACGCCTTGTACAAACTTGCAGCCCAAGAGAACAGGCCCGTCACGGACCATCTGGACGAGCAGGCAGTGCAGGGC
CTGAAGCAGATTCACCAGCAGCTCTATGATCGTCAGTTATACAGGGGTCTGGGAGGACAGCTCATGAGACAAGCAGTGTGTGTTTTAATA
GAAAAGTTGTCACTTTCCAAAATGCCCTTTAGAGGTGACACCGTAATTGATGGTTGGCAATGGCTGATAAATGACACTTTGAGACATCTC
CATCTCATCTCAAGTCACTCCCGCCAGCAGATGAAGGATGCAGCAGTCTCGGCCCTGGCTGCTCTATGCAGTGAATATTACATGAAGGAG
CCGGGGGAGGCAGATCCCGCAATTCAGGAGGAGCTGATCACGCAGTACCTGGCTGAGCTTCGGAACCCCGAGGAGATGACTCGCTGTGGC
TTCTCGTTGGCCTTGGGCGCCCTTCCAGGCTTCCTTCTGAAAGGCCGGCTCCAGCAGGTTCTCACAGGTTTAAGAGCAGTTACCCACACT
TCCCCCGAGGACGTAAGTTTTGCTGAGTCCAGGAGAGACGGCTTGAAGGCCATTGCGAGGATTTGCCAGACTGTTGGTGTGAAAGCAGGA
GCCCCAGACGAAGCTGTGTGCGGAGAGAATGTTTCCCAGATTTACTGTGCGCTGCTGGGCTGCATGGACGACTACACCACGGACAGCAGA
GGGGACGTGGGCACCTGGGTCCGCAAGGCCGCCATGACCAGTCTGATGGATCTGACACTTCTGCTGGCTCGGAGCCAGCCTGAGCTGATC
GAGGCCCATACCTGTGAGCGCATCATGTGCTGTGTGGCCCAGCAGGCCAGTGAGAAGATTGACCGTTTCCGTGCTCACGCCGCCAGCGTG
TTCCTGACGCTCCTGCACTTTGACAGCCCTCCCATCCCCCACGTGCCCCACCGAGGAGAACTGGAAAAGCTGTTTCCCAGGTCCGATGTG
GCCTCCGTGAACTGGAGTGCACCTTCCCAGGCCTTCCCACGCATCACCCAGCTCCTTGGGCTGCCCACCTACCGCTACCACGTCCTGCTG
GGGCTAGTCGTGTCCCTGGGCGGCTTGACGGAGTCGACGATCCGGCACTCCACCCAGAGCCTCTTTGAGTACATGAAGGGCATTCAGAGC
GACCCGCAGGCCCTGGGCAGCTTCAGCGGGACCCTTCTGCAGATCTTTGAGGACAACCTTCTGAATGAGAGGGTGTCCGTGCCGCTGCTG
AAGACGCTGGACCACGTGCTCACCCACGGCTGCTTCGACATCTTCACCACGGAGGAGGACCACCCCTTTGCTGTGAAGTTGCTTGCGCTC
TGTAAGAAAGAAATCAAGAATTCAAAAGATATCCAGAAGCTCCTGTCAGGCATCGCAGTTGACTTTCCAAGTGCGACACTCGTGTGTGTA
GGCACAGTGCAGATGTACGCACACACACACCTCCGGCTTGGGGCCCCAGGCCCGCACTGTGCTCACGGATCTGCTCTGCCCAGGTTCTGC
GAGATGGTGCAGTTCCCCGGCGACGTGAGGAGGCAGGCCCTCCTGCAGCTGTGTCTGCTCCTCTGCCACCGTTTCCCGCTGATCCGGAAG
ACCACGGCCAGCCAGGTGTACGAGACATTGCTCACCTACAGTGACGTCGTGGGCGCGGATGTGCTGGACGAGGTGGTGACTGTGCTCAGT
GACACTGCGTGGGACGCGGAGCTTGCAGTGGTGAGAGAGCAGCGCAACCGTCTGTGTGACCTTCTGGGCGTACCCAGGCCCCAGCTGGTG
CCCCAGCCTGGTGCCTGCTGAAGCCAGTCCTGGAGCCCATACCTCACCCCTGCCTGGTGAGGATGTCTTGTTCCTGAGGGAGGCCGGTGT
GGAAAGCCTCGCACAGTGGTGCCTCCAGCTGTTGAAGGGTAGCGCTGGCCCTTGGAGGCTGGCACTAGCTGACAGCTTTTCCTCTCTGCA

>In-frame_ENST00000335255_ENST00000539345_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80842020_length(amino acids)=899AA_start in transcript=111_stop in transcript=2810
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVALVIAAVFDRDINCRRAAS
AAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQ
VFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSK
MPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALGA
LPGFLLKGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWV
RKAAMTSLMDLTLLLARSQPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSA
PSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVL
THGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVDFPSATLVCVGTVQMYAHTHLRLGAPGPHCAHGSALPRFCEMVQFPG

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000355528_TCGA-BR-8382_FOXK2_chr17_80526077_+_TBCD_chr17_80897242_length(transcript)=1531nt_BP=936nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTGTGCACATTCAGGTTCCCGAGCACAAACATCAAGATA
ACGTTCACTGCCCTGTCCAGCGAGAAGAGAGAGAAGCAGGAGGCGTCTGAGTCTCCAGTGAAGGCCGTACAGCCACACATCTCGCCCCTG
ACCATCAACATTCCAGACACCATGGCCCACCTCATCAGCCCTCTGCCCTCCCCCACGGGAACCATCAGCGCTGCAAACTCCTGCCCCTCC
AGCCCCCGGGGAGCGGGGTCTTCAGGGTACAAGGTGGGCCGAGTGATGCCATCTGACCTCAATTTAATGGCTGACAACTCACAGCCTGAA
AATGAAAAGGAAGCTTCAGGTGGAGACAGCCCGAAGATCCGGAAGACCACGGCCAGCCAGGTGTACGAGACATTGCTCACCTACAGTGAC
GTCGTGGGCGCGGATGTGCTGGACGAGGTGGTGACTGTGCTCAGTGACACTGCGTGGGACGCGGAGCTTGCAGTGGTGAGAGAGCAGCGC
AACCGTCTGTGTGACCTTCTGGGCGTACCCAGGCCCCAGCTGGTGCCCCAGCCTGGTGCCTGCTGAAGCCAGTCCTGGAGCCCATACCTC
ACCCCTGCCTGGTGAGGATGTCTTGTTCCTGAGGGAGGCCGGTGTGGAAAGCCTCGCACAGTGGTGCCTCCAGCTGTTGAAGGGTAGCGC
TGGCCCTTGGAGGCTGGCACTAGCTGACAGCTTTTCCTCTCTGCACCTGCGCTCTGGTGACTTGGGGTGGACGCCTCTGCCTTCACTTGA
ACACAAATGTGCTTCCTATAAAATCATGTACCAAGAAGTTCCTGCCTTTTGTCTCTGAGCCTGATGTGTGTAGGGGTGATGGAAAGGCTC
ACTGCCCAGGGGTCAGCCAGAGGGGAGGTGGGCTGCACTCCTCCTGCCTGGAGACCAGGCCCCCTTCTTGCCTGGTGCTGTCCCTGCTGT

>In-frame_ENST00000335255_ENST00000355528_TCGA-BR-8382_FOXK2_chr17_80526077_+_TBCD_chr17_80897242_length(amino acids)=344AA_start in transcript=111_stop in transcript=1145
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSS
EKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASG

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000355528_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772716_length(transcript)=3334nt_BP=593nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTTTTCCAGGAGACTGACAAGGCGTGGCATGGGGGATGT
CTGGCGCTGGCAGAGCTGGGCAGGAGAGGCCTGTTGCTGCCGTCTCGACTCGTGGATGTTGTCGCCGTGATCCTGAAGGCGCTGACCTAC
GACGAGAAGCGGGGTGCCTGCAGCGTGGGCACCAACGTCAGGGACGCCGCCTGCTACGTGTGCTGGGCCTTCGCGCGTGCCTATGAGCCT
CAGGAGCTGAAGCCCTTTGTGACTGCAATCTCGAGTGCACTGGTGATTGCTGCGGTGTTTGACCGAGACATAAACTGCAGAAGAGCAGCC
TCTGCCGCCTTCCAGGAGAATGTGGGGAGACAGGGCACTTTCCCTCATGGTATTGATATTTTGACCACAGCTGACTATTTTGCCGTCGGT
AACAGATCCAACTGTTTCCTGGTTATAAGTGTGTTTATTGCCGGCTTTCCTGAGTACACGCAGCCAATGATAGACCACCTGGTTACCATG
AAGATCAGCCACTGGGATGGGGTCATCCGAGAGTTGGCTGCGAGGGCGCTGCACAACCTGGCCCAGCAGGCACCCGAGTTCAGCGCCACG
CAAGTCTTCCCGAGGCTGCTGTCCATGACACTGAGTCCAGATCTTCACATGAGGCATGGGTCGATTCTCGCCTGCGCAGAAGTTGCTTAC
GCCTTGTACAAACTTGCAGCCCAAGAGAACAGGCCCGTCACGGACCATCTGGACGAGCAGGCAGTGCAGGGCCTGAAGCAGATTCACCAG
CAGCTCTATGATCGTCAGTTATACAGGGGTCTGGGAGGACAGCTCATGAGACAAGCAGTGTGTGTTTTAATAGAAAAGTTGTCACTTTCC
AAAATGCCCTTTAGAGGTGACACCGTAATTGATGGTTGGCAATGGCTGATAAATGACACTTTGAGACATCTCCATCTCATCTCAAGTCAC
TCCCGCCAGCAGATGAAGGATGCAGCAGTCTCGGCCCTGGCTGCTCTATGCAGTGAATATTACATGAAGGAGCCGGGGGAGGCAGATCCC
GCAATTCAGGAGGAGCTGATCACGCAGTACCTGGCTGAGCTTCGGAACCCCGAGGAGATGACTCGCTGTGGCTTCTCGTTGGCCTTGGGC
GCCCTTCCAGGCTTCCTTCTGAAAGGCCGGCTCCAGCAGGTTCTCACAGGTTTAAGAGCAGTTACCCACACTTCCCCCGAGGACGTAAGT
TTTGCTGAGTCCAGGAGAGACGGCTTGAAGGCCATTGCGAGGATTTGCCAGACTGTTGGTGTGAAAGCAGGAGCCCCAGACGAAGCTGTG
TGCGGAGAGAATGTTTCCCAGATTTACTGTGCGCTGCTGGGCTGCATGGACGACTACACCACGGACAGCAGAGGGGACGTGGGCACCTGG
GTCCGCAAGGCCGCCATGACCAGTCTGATGGATCTGACACTTCTGCTGGCTCGGAGCCAGCCTGAGCTGATCGAGGCCCATACCTGTGAG
CGCATCATGTGCTGTGTGGCCCAGCAGGCCAGTGAGAAGATTGACCGTTTCCGTGCTCACGCCGCCAGCGTGTTCCTGACGCTCCTGCAC
TTTGACAGCCCTCCCATCCCCCACGTGCCCCACCGAGGAGAACTGGAAAAGCTGTTTCCCAGGTCCGATGTGGCCTCCGTGAACTGGAGT
GCACCTTCCCAGGCCTTCCCACGCATCACCCAGCTCCTTGGGCTGCCCACCTACCGCTACCACGTCCTGCTGGGGCTAGTCGTGTCCCTG
GGCGGCTTGACGGAGTCGACGATCCGGCACTCCACCCAGAGCCTCTTTGAGTACATGAAGGGCATTCAGAGCGACCCGCAGGCCCTGGGC
AGCTTCAGCGGGACCCTTCTGCAGATCTTTGAGGACAACCTTCTGAATGAGAGGGTGTCCGTGCCGCTGCTGAAGACGCTGGACCACGTG
CTCACCCACGGCTGCTTCGACATCTTCACCACGGAGGAGGACCACCCCTTTGCTGTGAAGTTGCTTGCGCTCTGTAAGAAAGAAATCAAG
AATTCAAAAGATATCCAGAAGCTCCTGTCAGGCATCGCAGTGTTCTGCGAGATGGTGCAGTTCCCCGGCGACGTGAGGAGGCAGGCCCTC
CTGCAGCTGTGTCTGCTCCTCTGCCACCGTTTCCCGCTGATCCGGAAGACCACGGCCAGCCAGGTGTACGAGACATTGCTCACCTACAGT
GACGTCGTGGGCGCGGATGTGCTGGACGAGGTGGTGACTGTGCTCAGTGACACTGCGTGGGACGCGGAGCTTGCAGTGGTGAGAGAGCAG
CGCAACCGTCTGTGTGACCTTCTGGGCGTACCCAGGCCCCAGCTGGTGCCCCAGCCTGGTGCCTGCTGAAGCCAGTCCTGGAGCCCATAC
CTCACCCCTGCCTGGTGAGGATGTCTTGTTCCTGAGGGAGGCCGGTGTGGAAAGCCTCGCACAGTGGTGCCTCCAGCTGTTGAAGGGTAG
CGCTGGCCCTTGGAGGCTGGCACTAGCTGACAGCTTTTCCTCTCTGCACCTGCGCTCTGGTGACTTGGGGTGGACGCCTCTGCCTTCACT
TGAACACAAATGTGCTTCCTATAAAATCATGTACCAAGAAGTTCCTGCCTTTTGTCTCTGAGCCTGATGTGTGTAGGGGTGATGGAAAGG
CTCACTGCCCAGGGGTCAGCCAGAGGGGAGGTGGGCTGCACTCCTCCTGCCTGGAGACCAGGCCCCCTTCTTGCCTGGTGCTGTCCCTGC

>In-frame_ENST00000335255_ENST00000355528_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772716_length(amino acids)=945AA_start in transcript=111_stop in transcript=2948
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVFQETDKAWHGGCLALAELG
RRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQEN
VGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLL
SMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGD
TVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALGALPGFLL
KGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMT
SLMDLTLLLARSQPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFP
RITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFD
IFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGADV

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000397466_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772716_length(transcript)=1464nt_BP=593nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTTTTCCAGGAGACTGACAAGGCGTGGCATGGGGGATGT
CTGGCGCTGGCAGAGCTGGGCAGGAGAGGCCTGTTGCTGCCGTCTCGACTCGTGGATGTTGTCGCCGTGATCCTGAAGGCGCTGACCTAC
GACGAGAAGCGGGGTGCCTGCAGCGTGGGCACCAACGTCAGGGACGCCGCCTGCTACGTGTGCTGGGCCTTCGCGCGTGCCTATGAGCCT
CAGGAGCTGAAGCCCTTTGTGACTGCAATCTCGAGTGCACTGGTGATTGCTGCGGTGTTTGACCGAGACATAAACTGCAGAAGAGCAGCC
TCTGCCGCCTTCCAGGAGAATGTGGGGAGACAGGGCACTTTCCCTCATGGTATTGATATTTTGACCACAGCTGACTATTTTGCCGTCGGT
AACAGATCCAACTGTTTCCTGGTTATAAGTGTGTTTATTGCCGGCTTTCCTGAGTACACGCAGCCAATGATAGACCACCTGGTTACCATG
AAGATCAGCCACTGGGATGGGGTCATCCGAGAGTTGGCTGCGAGGGCGCTGCACAACCTGGCCCAGCAGGCACCCGAGTTCAGCGCCACG
CAAGTCTTCCCGAGGCTGCTGTCCATGACACTGAGTCCAGATCTTCACATGAGGCATGGGTCGATTCTCGCCTGCGCAGAAGTTGCTTAC
GCCTTGTACAAACTTGCAGCCCAAGAGAACAGGCCCGTCACGGACCATCTGGACGAGCAGGCAGTGCAGGGCCTGAAGCAGATTCACCAG
CAGCCGTGCATCTGCAGCTGGGGTCTGATGTCTCCTGAAAGTAAAGCAGAATTTTGTGTGTGCGTCTGTCGGATTTCTCTGGGGAGACAG

>In-frame_ENST00000335255_ENST00000397466_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772716_length(amino acids)=450AA_start in transcript=111_stop in transcript=1463
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVFQETDKAWHGGCLALAELG
RRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQEN
VGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLL
SMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQPCICSWGLMSPESKAEFCVCVCRISLGRQCVHLSGL

--------------------------------------------------------------
>In-frame_ENST00000335255_ENST00000539345_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772716_length(transcript)=3309nt_BP=593nt
CGGCCGCGCGTGCTCCCGCCCCTCGCCGCCGCTCGCTCGCTCGCCGGCCGGCGGCCTCCGCTCGGCCCCCTCCCTCAGCTCCGGTGCGCG
GCGGCCGACGACCCGCGCGGCCTGGGCCTCGGCCCGCGCCACCGGCGCCCGCGCGGAGCGGCCCGGGGGCCCTCACGCAGGCCCATGGCG
GCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCCGGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCG
GGCGGCTGGGCCGTGGCGCGCCTGGAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCGTCGCAG
GGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTCGAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGC
GGGGCCGCTCCGGAGCTGCCGCCCGCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGGGTATTC
GTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTTTTCCAGGAGACTGACAAGGCGTGGCATGGGGGATGT
CTGGCGCTGGCAGAGCTGGGCAGGAGAGGCCTGTTGCTGCCGTCTCGACTCGTGGATGTTGTCGCCGTGATCCTGAAGGCGCTGACCTAC
GACGAGAAGCGGGGTGCCTGCAGCGTGGGCACCAACGTCAGGGACGCCGCCTGCTACGTGTGCTGGGCCTTCGCGCGTGCCTATGAGCCT
CAGGAGCTGAAGCCCTTTGTGACTGCAATCTCGAGTGCACTGGTGATTGCTGCGGTGTTTGACCGAGACATAAACTGCAGAAGAGCAGCC
TCTGCCGCCTTCCAGGAGAATGTGGGGAGACAGGGCACTTTCCCTCATGGTATTGATATTTTGACCACAGCTGACTATTTTGCCGTCGGT
AACAGATCCAACTGTTTCCTGGTTATAAGTGTGTTTATTGCCGGCTTTCCTGAGTACACGCAGCCAATGATAGACCACCTGGTTACCATG
AAGATCAGCCACTGGGATGGGGTCATCCGAGAGTTGGCTGCGAGGGCGCTGCACAACCTGGCCCAGCAGGCACCCGAGTTCAGCGCCACG
CAAGTCTTCCCGAGGCTGCTGTCCATGACACTGAGTCCAGATCTTCACATGAGGCATGGGTCGATTCTCGCCTGCGCAGAAGTTGCTTAC
GCCTTGTACAAACTTGCAGCCCAAGAGAACAGGCCCGTCACGGACCATCTGGACGAGCAGGCAGTGCAGGGCCTGAAGCAGATTCACCAG
CAGCTCTATGATCGTCAGTTATACAGGGGTCTGGGAGGACAGCTCATGAGACAAGCAGTGTGTGTTTTAATAGAAAAGTTGTCACTTTCC
AAAATGCCCTTTAGAGGTGACACCGTAATTGATGGTTGGCAATGGCTGATAAATGACACTTTGAGACATCTCCATCTCATCTCAAGTCAC
TCCCGCCAGCAGATGAAGGATGCAGCAGTCTCGGCCCTGGCTGCTCTATGCAGTGAATATTACATGAAGGAGCCGGGGGAGGCAGATCCC
GCAATTCAGGAGGAGCTGATCACGCAGTACCTGGCTGAGCTTCGGAACCCCGAGGAGATGACTCGCTGTGGCTTCTCGTTGGCCTTGGGC
GCCCTTCCAGGCTTCCTTCTGAAAGGCCGGCTCCAGCAGGTTCTCACAGGTTTAAGAGCAGTTACCCACACTTCCCCCGAGGACGTAAGT
TTTGCTGAGTCCAGGAGAGACGGCTTGAAGGCCATTGCGAGGATTTGCCAGACTGTTGGTGTGAAAGCAGGAGCCCCAGACGAAGCTGTG
TGCGGAGAGAATGTTTCCCAGATTTACTGTGCGCTGCTGGGCTGCATGGACGACTACACCACGGACAGCAGAGGGGACGTGGGCACCTGG
GTCCGCAAGGCCGCCATGACCAGTCTGATGGATCTGACACTTCTGCTGGCTCGGAGCCAGCCTGAGCTGATCGAGGCCCATACCTGTGAG
CGCATCATGTGCTGTGTGGCCCAGCAGGCCAGTGAGAAGATTGACCGTTTCCGTGCTCACGCCGCCAGCGTGTTCCTGACGCTCCTGCAC
TTTGACAGCCCTCCCATCCCCCACGTGCCCCACCGAGGAGAACTGGAAAAGCTGTTTCCCAGGTCCGATGTGGCCTCCGTGAACTGGAGT
GCACCTTCCCAGGCCTTCCCACGCATCACCCAGCTCCTTGGGCTGCCCACCTACCGCTACCACGTCCTGCTGGGGCTAGTCGTGTCCCTG
GGCGGCTTGACGGAGTCGACGATCCGGCACTCCACCCAGAGCCTCTTTGAGTACATGAAGGGCATTCAGAGCGACCCGCAGGCCCTGGGC
AGCTTCAGCGGGACCCTTCTGCAGATCTTTGAGGACAACCTTCTGAATGAGAGGGTGTCCGTGCCGCTGCTGAAGACGCTGGACCACGTG
CTCACCCACGGCTGCTTCGACATCTTCACCACGGAGGAGGACCACCCCTTTGCTGTGAAGTTGCTTGCGCTCTGTAAGAAAGAAATCAAG
AATTCAAAAGATATCCAGAAGCTCCTGTCAGGCATCGCAGTTGACTTTCCAAGTGCGACACTCGTGTGTGTAGGCACAGTGCAGATGTAC
GCACACACACACCTCCGGCTTGGGGCCCCAGGCCCGCACTGTGCTCACGGATCTGCTCTGCCCAGGTTCTGCGAGATGGTGCAGTTCCCC
GGCGACGTGAGGAGGCAGGCCCTCCTGCAGCTGTGTCTGCTCCTCTGCCACCGTTTCCCGCTGATCCGGAAGACCACGGCCAGCCAGGTG
TACGAGACATTGCTCACCTACAGTGACGTCGTGGGCGCGGATGTGCTGGACGAGGTGGTGACTGTGCTCAGTGACACTGCGTGGGACGCG
GAGCTTGCAGTGGTGAGAGAGCAGCGCAACCGTCTGTGTGACCTTCTGGGCGTACCCAGGCCCCAGCTGGTGCCCCAGCCTGGTGCCTGC
TGAAGCCAGTCCTGGAGCCCATACCTCACCCCTGCCTGGTGAGGATGTCTTGTTCCTGAGGGAGGCCGGTGTGGAAAGCCTCGCACAGTG
GTGCCTCCAGCTGTTGAAGGGTAGCGCTGGCCCTTGGAGGCTGGCACTAGCTGACAGCTTTTCCTCTCTGCACCTGCGCTCTGGTGACTT

>In-frame_ENST00000335255_ENST00000539345_TCGA-66-2781_FOXK2_chr17_80478183_+_TBCD_chr17_80772716_length(amino acids)=983AA_start in transcript=111_stop in transcript=3062
MGLGPRHRRPRGAARGPSRRPMAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSM
GHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVFQETDKAWHGGCLALAELG
RRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQEN
VGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLL
SMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGD
TVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALGALPGFLL
KGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMT
SLMDLTLLLARSQPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFP
RITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFD
IFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVDFPSATLVCVGTVQMYAHTHLRLGAPGPHCAHGSALPRFCEMVQFPGDVRRQA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FOXK2-TBCD


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FOXK2-TBCD


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FOXK2-TBCD


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneTBCDC4310671ENCEPHALOPATHY, PROGRESSIVE, EARLY-ONSET, WITH BRAIN ATROPHY AND THIN CORPUS CALLOSUM4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneTBCDC0025958Microcephaly2CTD_human
TgeneTBCDC0036572Seizures2CTD_human;GENOMICS_ENGLAND
TgeneTBCDC1956147Microlissencephaly2CTD_human
TgeneTBCDC3853041Severe Congenital Microcephaly2CTD_human
TgeneTBCDC0008073Developmental Disabilities1CTD_human
TgeneTBCDC0020796Profound Mental Retardation1CTD_human
TgeneTBCDC0022333Jacksonian Seizure1CTD_human
TgeneTBCDC0023944Locked-In Syndrome1CTD_human
TgeneTBCDC0025363Mental Retardation, Psychosocial1CTD_human
TgeneTBCDC0029124Optic Atrophy1CTD_human
TgeneTBCDC0034372Quadriplegia1CTD_human
TgeneTBCDC0035229Respiratory Insufficiency1CTD_human
TgeneTBCDC0037769West Syndrome1GENOMICS_ENGLAND
TgeneTBCDC0085996Child Development Deviations1CTD_human
TgeneTBCDC0085997Child Development Disorders, Specific1CTD_human
TgeneTBCDC0149958Complex partial seizures1CTD_human
TgeneTBCDC0151786Muscle Weakness1CTD_human
TgeneTBCDC0234533Generalized seizures1CTD_human
TgeneTBCDC0234535Clonic Seizures1CTD_human
TgeneTBCDC0235063Respiratory Depression1CTD_human
TgeneTBCDC0270715Degenerative Diseases, Central Nervous System1CTD_human
TgeneTBCDC0270790Quadriparesis1CTD_human
TgeneTBCDC0270824Visual seizure1CTD_human
TgeneTBCDC0270844Tonic Seizures1CTD_human
TgeneTBCDC0270846Epileptic drop attack1CTD_human
TgeneTBCDC0422850Seizures, Somatosensory1CTD_human
TgeneTBCDC0422852Seizures, Auditory1CTD_human
TgeneTBCDC0422853Olfactory seizure1CTD_human
TgeneTBCDC0422854Gustatory seizure1CTD_human
TgeneTBCDC0422855Vertiginous seizure1CTD_human
TgeneTBCDC0426970Spastic Quadriplegia1CTD_human
TgeneTBCDC0431380Cortical Dysplasia1CTD_human
TgeneTBCDC0494475Tonic - clonic seizures1CTD_human
TgeneTBCDC0524851Neurodegenerative Disorders1CTD_human
TgeneTBCDC0751056Non-epileptic convulsion1CTD_human
TgeneTBCDC0751110Single Seizure1CTD_human
TgeneTBCDC0751123Atonic Absence Seizures1CTD_human
TgeneTBCDC0751460Flaccid Quadriplegia1CTD_human
TgeneTBCDC0751461Paralysis, Spinal, Quadriplegic1CTD_human
TgeneTBCDC0751494Convulsive Seizures1CTD_human
TgeneTBCDC0751495Seizures, Focal1CTD_human
TgeneTBCDC0751496Seizures, Sensory1CTD_human
TgeneTBCDC0751733Degenerative Diseases, Spinal Cord1CTD_human
TgeneTBCDC0917816Mental deficiency1CTD_human
TgeneTBCDC1145670Respiratory Failure1CTD_human
TgeneTBCDC1955869Malformations of Cortical Development1CTD_human
TgeneTBCDC3495874Nonepileptic Seizures1CTD_human
TgeneTBCDC3714756Intellectual Disability1CTD_human
TgeneTBCDC4048158Convulsions1CTD_human
TgeneTBCDC4316903Absence Seizures1CTD_human
TgeneTBCDC4317109Epileptic Seizures1CTD_human
TgeneTBCDC4317123Myoclonic Seizures1CTD_human
TgeneTBCDC4505436Generalized Absence Seizures1CTD_human