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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GFM1-LRBA (FusionGDB2 ID:32831)

Fusion Gene Summary for GFM1-LRBA

check button Fusion gene summary
Fusion gene informationFusion gene name: GFM1-LRBA
Fusion gene ID: 32831
HgeneTgene
Gene symbol

GFM1

LRBA

Gene ID

85476

987

Gene nameG elongation factor mitochondrial 1LPS responsive beige-like anchor protein
SynonymsCOXPD1|EFG|EFG1|EFGM|EGF1|GFM|hEFG1|mtEF-G1BGL|CDC4L|CVID8|LAB300|LBA
Cytomap

3q25.32

4q31.3

Type of geneprotein-codingprotein-coding
Descriptionelongation factor G, mitochondrialG translation elongation factor, mitochondrialmitochondrial elongation factor Gmitochondrial elongation factor G1lipopolysaccharide-responsive and beige-like anchor proteinCDC4-like proteinLPS-responsive vesicle trafficking, beach and anchor containingvesicle trafficking, beach and anchor containing
Modification date2020031320200320
UniProtAcc

Q96RP9

P50851

Ensembl transtripts involved in fusion geneENST00000486715, ENST00000478576, 
ENST00000264263, ENST00000490261, 
ENST00000535741, ENST00000510413, 
ENST00000503716, ENST00000357115, 
ENST00000507224, 
Fusion gene scores* DoF score7 X 7 X 5=24525 X 25 X 10=6250
# samples 727
** MAII scorelog2(7/245*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(27/6250*10)=-4.53282487738598
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GFM1 [Title/Abstract] AND LRBA [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGFM1(158399946)-LRBA(151770150), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGFM1

GO:0070125

mitochondrial translational elongation

19716793


check buttonFusion gene breakpoints across GFM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across LRBA (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRCTCGA-BP-4352-01AGFM1chr3

158399946

+LRBAchr4

151770150

-


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Fusion Gene ORF analysis for GFM1-LRBA

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000486715ENST00000535741GFM1chr3

158399946

+LRBAchr4

151770150

-
In-frameENST00000486715ENST00000510413GFM1chr3

158399946

+LRBAchr4

151770150

-
5CDS-intronENST00000486715ENST00000503716GFM1chr3

158399946

+LRBAchr4

151770150

-
5CDS-intronENST00000486715ENST00000357115GFM1chr3

158399946

+LRBAchr4

151770150

-
5CDS-intronENST00000486715ENST00000507224GFM1chr3

158399946

+LRBAchr4

151770150

-
In-frameENST00000478576ENST00000535741GFM1chr3

158399946

+LRBAchr4

151770150

-
In-frameENST00000478576ENST00000510413GFM1chr3

158399946

+LRBAchr4

151770150

-
5CDS-intronENST00000478576ENST00000503716GFM1chr3

158399946

+LRBAchr4

151770150

-
5CDS-intronENST00000478576ENST00000357115GFM1chr3

158399946

+LRBAchr4

151770150

-
5CDS-intronENST00000478576ENST00000507224GFM1chr3

158399946

+LRBAchr4

151770150

-
In-frameENST00000264263ENST00000535741GFM1chr3

158399946

+LRBAchr4

151770150

-
In-frameENST00000264263ENST00000510413GFM1chr3

158399946

+LRBAchr4

151770150

-
5CDS-intronENST00000264263ENST00000503716GFM1chr3

158399946

+LRBAchr4

151770150

-
5CDS-intronENST00000264263ENST00000357115GFM1chr3

158399946

+LRBAchr4

151770150

-
5CDS-intronENST00000264263ENST00000507224GFM1chr3

158399946

+LRBAchr4

151770150

-
intron-3CDSENST00000490261ENST00000535741GFM1chr3

158399946

+LRBAchr4

151770150

-
intron-3CDSENST00000490261ENST00000510413GFM1chr3

158399946

+LRBAchr4

151770150

-
intron-intronENST00000490261ENST00000503716GFM1chr3

158399946

+LRBAchr4

151770150

-
intron-intronENST00000490261ENST00000357115GFM1chr3

158399946

+LRBAchr4

151770150

-
intron-intronENST00000490261ENST00000507224GFM1chr3

158399946

+LRBAchr4

151770150

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000486715GFM1chr3158399946+ENST00000535741LRBAchr4151770150-7802212135765212054
ENST00000486715GFM1chr3158399946+ENST00000510413LRBAchr4151770150-7710212135765182053
ENST00000478576GFM1chr3158399946+ENST00000535741LRBAchr4151770150-76651984199063841464
ENST00000478576GFM1chr3158399946+ENST00000510413LRBAchr4151770150-75731984199063811463
ENST00000264263GFM1chr3158399946+ENST00000535741LRBAchr4151770150-754018593862592073
ENST00000264263GFM1chr3158399946+ENST00000510413LRBAchr4151770150-744818593862562072

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000486715ENST00000535741GFM1chr3158399946+LRBAchr4151770150-0.0005873350.99941266
ENST00000486715ENST00000510413GFM1chr3158399946+LRBAchr4151770150-0.0005848960.99941516
ENST00000478576ENST00000535741GFM1chr3158399946+LRBAchr4151770150-0.0028045890.99719536
ENST00000478576ENST00000510413GFM1chr3158399946+LRBAchr4151770150-0.0025215490.9974784
ENST00000264263ENST00000535741GFM1chr3158399946+LRBAchr4151770150-0.0004328940.9995671
ENST00000264263ENST00000510413GFM1chr3158399946+LRBAchr4151770150-0.0004352320.9995647

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Fusion Genomic Features for GFM1-LRBA


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GFM1-LRBA


check button Go to

FGviewer for the breakpoints of chr3:158399946-chr4:151770150

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GFM1

Q96RP9

LRBA

P50851

FUNCTION: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. {ECO:0000255|HAMAP-Rule:MF_03061, ECO:0000269|PubMed:19716793}.FUNCTION: May be involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGFM1chr3:158399946chr4:151770150ENST00000264263+151944_321607.0771.0DomainNote=tr-type G
HgeneGFM1chr3:158399946chr4:151770150ENST00000486715+141844_321588.0752.0DomainNote=tr-type G
HgeneGFM1chr3:158399946chr4:151770150ENST00000264263+1519120_124607.0771.0Nucleotide bindingGTP
HgeneGFM1chr3:158399946chr4:151770150ENST00000264263+1519174_177607.0771.0Nucleotide bindingGTP
HgeneGFM1chr3:158399946chr4:151770150ENST00000264263+151953_60607.0771.0Nucleotide bindingGTP
HgeneGFM1chr3:158399946chr4:151770150ENST00000486715+1418120_124588.0752.0Nucleotide bindingGTP
HgeneGFM1chr3:158399946chr4:151770150ENST00000486715+1418174_177588.0752.0Nucleotide bindingGTP
HgeneGFM1chr3:158399946chr4:151770150ENST00000486715+141853_60588.0752.0Nucleotide bindingGTP
TgeneLRBAchr3:158399946chr4:151770150ENST0000035711524581990_19941386.02864.0Compositional biasNote=Poly-Arg
TgeneLRBAchr3:158399946chr4:151770150ENST0000051041324571990_19941386.02852.0Compositional biasNote=Poly-Arg
TgeneLRBAchr3:158399946chr4:151770150ENST0000035711524582073_21811386.02864.0DomainBEACH-type PH
TgeneLRBAchr3:158399946chr4:151770150ENST0000035711524582200_24891386.02864.0DomainBEACH
TgeneLRBAchr3:158399946chr4:151770150ENST0000051041324572073_21811386.02852.0DomainBEACH-type PH
TgeneLRBAchr3:158399946chr4:151770150ENST0000051041324572200_24891386.02852.0DomainBEACH
TgeneLRBAchr3:158399946chr4:151770150ENST0000035711524582591_26331386.02864.0RepeatNote=WD 2
TgeneLRBAchr3:158399946chr4:151770150ENST0000035711524582636_26791386.02864.0RepeatNote=WD 3
TgeneLRBAchr3:158399946chr4:151770150ENST0000035711524582695_27351386.02864.0RepeatNote=WD 4
TgeneLRBAchr3:158399946chr4:151770150ENST0000035711524582777_28161386.02864.0RepeatNote=WD 5
TgeneLRBAchr3:158399946chr4:151770150ENST0000035711524582819_28581386.02864.0RepeatNote=WD 6
TgeneLRBAchr3:158399946chr4:151770150ENST0000051041324572591_26331386.02852.0RepeatNote=WD 2
TgeneLRBAchr3:158399946chr4:151770150ENST0000051041324572636_26791386.02852.0RepeatNote=WD 3
TgeneLRBAchr3:158399946chr4:151770150ENST0000051041324572695_27351386.02852.0RepeatNote=WD 4
TgeneLRBAchr3:158399946chr4:151770150ENST0000051041324572777_28161386.02852.0RepeatNote=WD 5
TgeneLRBAchr3:158399946chr4:151770150ENST0000051041324572819_28581386.02852.0RepeatNote=WD 6
TgeneLRBAchr3:158399946chr4:151770150ENST0000035711524581531_15481386.02864.0TransmembraneHelical
TgeneLRBAchr3:158399946chr4:151770150ENST0000051041324571531_15481386.02852.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLRBAchr3:158399946chr4:151770150ENST0000035711524581006_10531386.02864.0Coiled coilOntology_term=ECO:0000255
TgeneLRBAchr3:158399946chr4:151770150ENST0000051041324571006_10531386.02852.0Coiled coilOntology_term=ECO:0000255
TgeneLRBAchr3:158399946chr4:151770150ENST0000035711524581301_13431386.02864.0RepeatNote=WD 1
TgeneLRBAchr3:158399946chr4:151770150ENST0000051041324571301_13431386.02852.0RepeatNote=WD 1


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Fusion Gene Sequence for GFM1-LRBA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000486715_ENST00000535741_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(transcript)=7802nt_BP=2121nt
TTCTGTATCTTCATACAGAGGTAATATTTAAAAAAGAAGACGAAGACAAAAGGACTCCCTTCCCTCACCCATATACCTATGCCGTCTTAC
TGGGAGCAAACACTTCTTTAGCTCCGCAAAGCGATTGCACTTTCTCTTCCAAGTCGGCAGACGGCGCGCGAGCAGCGTAGGCACTGCTCC
GCCTCCAATCCAGTTGCTCTTCTTTCTTTTCCTCACTCTCTTTTTCCTCGCGTCCTTTGCCCCGGAAGTGCTCTTACAACATTGGCTGCC
GGCGTGACTTTGACCGCTTCCCGGTGCGTTACCGGCAGCTGAACCCACCCGGCGCCACGGGACTTTGACGCGTGCTCTGCGCTTGCCATG
AGACTCCTGGGAGCTGCAGCCGTCGCGGCTCTGGGGCGCGGAAGGGCCCCCGCCTCCCTAGGCTGGCAGAGGAAGCAGGTTAATTGGAAG
GCCTGCCGATGGTCTTCATCAGGGGTGATTCCTAATGAAAAAATACGAAATATTGGAATCTCAGCTCACATTGATTCTGGGAAAACTACA
TTAACAGAACGAGTCCTTTACTACACTGGCAGAATTGCAAAGATGCATGAGGTGAAAGGTAAAGATGGAGTTGGTGCTGTCATGGATTCC
ATGGAACTAGAGAGACAAAGAGGAATCACTATTCAGTCAGCAGCCACTTACACCATGTGGAAAGATGTCAATATTAACATTATAGATACT
CCTGGGCATGTGGACTTCACAATAGAAGTGGAAAGGGCCCTGAGAGTGTTGGATGGTGCAGTCCTTGTTCTCTGTGCTGTTGGAGGGGTA
CAGTGCCAGACCATGACTGTCAATCGTCAGATGAAGCGCTACAACGTTCCGTTTCTAACTTTTATTAACAAATTGGACCGAATGGGCTCC
AACCCAGCCAGGGCCCTGCAGCAAATGAGGTCTAAACTAAATCATAATGCAGCGTTTATGCAGATACCCATGGGTTTGGAGGGTAATTTT
AAAGGTATTGTAGATCTTATTGAGGAACGAGCCATCTATTTTGATGGAGACTTTGGTCAGATTGTTCGATATGGTGAGATTCCAGCTGAA
TTAAGGGCGGCGGCCACTGACCACCGGCAGGAGCTAATTGAATGTGTTGCCAATTCAGATGAACAGCTTGGTGAGATGTTTCTGGAAGAA
AAAATCCCCTCGATTTCTGATTTAAAGCTAGCAATTCGAAGAGCTACTCTGAAAAGATCATTTACTCCTGTATTTTTGGGAAGCGCCTTG
AAGAACAAAGGAGTTCAGCCTCTTTTAGATGCTGTTTTAGAATACCTCCCAAATCCATCTGAAGTCCAGAACTATGCTATTCTCAATAAA
GAGGATGACTCAAAAGAGAAAACCAAAATCCTAATGAACTCCAGTAGAGACAATTCCCACCCATTTGTAGGCCTGGCTTTTAAACTGGAG
GTAGGTCGATTTGGACAATTAACTTATGTTCGCAGTTATCAGGGAGAGCTAAAGAAGGGTGACACCATCTATAACACAAGGACAAGAAAG
AAAGTACGGTTGCAACGGCTGGCTCGCATGCATGCCGACATGATGGAGGATGTTGAGGAAGTATATGCCGGAGACATCTGTGCATTGTTT
GGCATTGACTGTGCTAGTGGAGACACATTCACAGACAAAGCCAACAGCGGCCTTTCTATGGAGTCAATTCATGTTCCTGATCCTGTCATT
TCAATAGCAATGAAGCCTTCTAACAAGAACGATCTGGAAAAATTTTCAAAAGGTATTGGCAGGTTTACAAGAGAAGATCCCACATTTAAA
GTATACTTTGACACTGAGAACAAAGAGACAGTTATATCTGGAATGGGAGAATTACACCTGGAAATCTATGCTCAGAGGCTGGAAAGAGAG
TATGGCTGTCCTTGTATCACAGGAAAGCCAAAAGTTGCCTTTCGAGAGACCATTACTGCCCCTGTCCCGTTTGACTTTACACATAAAAAA
CAATCAGGTGGTGCAGGCCAGTATGGAAAAGTAATAGGTGTCCTGGAGCCTCTGGACCCAGAGGACTACACTAAATTGGAATTTTCAGAT
GAAACATTCGGATCAAATATTCCAAAGCAGTTTGTGCCTGCTGTAGAAAAGCATGAACTGGAAAATATTGAACCTACTCAAGGCCTTTCA
ATAGAAGCCTCTGTGACATTTTTGCAGAGGCTAATTAGCCTTGTGGATGTGCTTATATTTGCAAGTTCTCTTGGCTTTACTGAAATTGAA
GCTGAAAAAAGTATGTCATCTGGAGGAATTTTGCGGCAGTGTCTCCGACTAGTTTGTGCAGTCGCAGTAAGGAATTGCTTGGAGTGTCAA
CAGCATTCACAACTGAAAACTAGGGGAGATAAAGCCTTGAAACCAATGCATAGCCTTATTCCTTTAGGGAAATCTGCAGCGAAGAGCCCA
GTGGACATTGTGACTGGCGGTATATCTCCAGTAAGAGATCTTGACAGGCTTCTACAGGACATGGATATTAATCGGCTTAGGGCAGTTGTT
TTCAGAGACATAGAGGATAGCAAACAAGCTCAATTTTTAGCCTTGGCAGTAGTATACTTTATCTCTGTTCTTATGGTCTCCAAGTACAGA
GACATTTTGGAACCCCAAAATGAAAGGCATAGCCAGTCATGTACAGAAACTGGCAGTGAAAATGAGAATGTATCACTCTCTGAAATCACA
CCAGCAGCATTCAGCACTTTAACTACGGCATCAGTGGAAGAATCTGAAAGCACATCATCTGCTCGAAGGAGGGACTCAGGCATTGGGGAA
GAAACAGCCACTGGTTTAGGAAGCCATGTGGAAGTAACTCCTCACACAGCACCTCCTGGTGTCAGTGCAGGCCCAGATGCAATCAGCGAG
GTGCTATCTACTCTTTCTTTAGAAGTCAATAAGTCTCCGGAAACCAAAAATGATAGAGGAAATGACTTGGACACTAAGGCTACACCGTCA
GTTTCAGTTTCAAAAAACGTCAATGTGAAAGACATTCTCCGAAGCTTGGTTAACATACCAGCAGATGGAGTCACAGTGGATCCTGCCCTT
CTGCCACCAGCCTGCCTTGGAGCCCTTGGTGATCTATCTGTGGAACAACCCGTGCAGTTCAGATCTTTTGACAGAAGTGTCATTGTTGCA
GCAAAAAAGTCAGCAGTCTCACCTTCCACCTTTAATACAAGCATACCTACCAATGCTGTCAGTGTGGTTTCCTCAGTAGATTCAGCCCAA
GCCTCAGATATGGGAGGAGAATCACCAGGCAGTAGATCATCTAATGCAAAATTGCCCTCAGTTCCAACAGTTGATTCAGTTTCACAAGAT
CCGGTTTCAAATATGAGTATTACAGAGAGGCTTGAACACGCTTTGGAAAAGGCAGCTCCTCTCCTTCGTGAGATTTTTGTGGATTTTGCA
CCTTTTCTTTCTCGGACACTTTTGGGTAGCCATGGACAAGAACTGCTTATAGAAGGAACAAGTCTGGTTTGCATGAAGTCGAGTAGTTCA
GTTGTGGAATTGGTTATGCTACTGTGTTCTCAGGAGTGGCAAAATTCTATTCAGAAGAATGCAGGCCTTGCTTTTATCGAACTTGTCAAT
GAAGGAAGGTTGCTTAGCCAGACAATGAAGGATCATCTAGTAAGAGTAGCAAATGAAGCTGAATTTATCCTGAGCAGGCAGAGAGCAGAA
GATATTCACAGACATGCGGAATTTGAGTCACTGTGTGCCCAGTATTCTGCAGACAAACGAGAAGATGAGAAGATGTGTGATCATTTGATA
AGAGCAGCAAAATATCGTGACCACGTGACAGCAACTCAACTAATCCAGAAAATTATCAACATTCTCACAGACAAGCATGGAGCCTGGGGA
AATTCTGCAGTGAGTCGTCCTCTTGAGTTCTGGCGCCTTGACTACTGGGAAGATGACTTGCGGCGCCGGCGACGATTTGTGCGTAACCCT
CTAGGATCGACACATCCTGAAGCGACACTAAAAACAGCCGTGGAACATGCCACAGATGAAGATATCCTTGCTAAAGGAAAACAGTCCATC
AGGAGTCAGGCTTTAGGAAATCAGAACTCAGAAAACGAGATCCTCCTGGAAGGCGATGATGATACTCTGTCATCCGTGGATGAGAAAGAT
TTAGAGAATCTTGCCGGTCCTGTTAGCCTGAGCACACCAGCTCAGCTTGTGGCCCCCTCTGTTGTAGTAAAGGGCACTCTTTCTGTCACC
TCCTCCGAACTCTATTTTGAGGTGGATGAAGAGGATCCTAACTTCAAAAAAATCGACCCCAAGATCTTGGCATATACAGAAGGGCTGCAT
GGAAAATGGCTGTTCACAGAGATACGATCAATCTTTTCTCGTCGTTATCTTTTGCAAAATACAGCCCTGGAGATCTTTATGGCAAACAGA
GTTGCTGTGATGTTCAACTTCCCAGACCCTGCAACAGTAAAGAAAGTGGTTAACTATCTACCTCGTGTTGGCGTTGGAACAAGTTTTGGA
TTGCCTCAAACCAGACGTATTTCATTAGCTAGTCCACGTCAGCTTTTTAAGGCTTCTAATATGACCCAGCGATGGCAACACAGAGAGATA
TCTAATTTTGAGTACTTGATGTTTCTCAACACGATAGCAGGACGGAGTTATAATGACTTAAATCAGTATCCAGTGTTTCCTTGGGTCATC
ACTAATTATGAATCAGAAGAACTGGATCTTACCTTGCCCACCAACTTCAGAGATTTGTCCAAGCCAATAGGAGCTCTGAACCCAAAAAGA
GCAGCATTCTTCGCTGAGCGTTATGAATCATGGGAAGATGATCAAGTTCCAAAGTTTCACTATGGTACTCATTACTCAACTGCAAGTTTT
GTTCTTGCATGGCTGCTAAGAATAGAACCCTTTACAACTTATTTCCTAAATTTGCAAGGAGGCAAATTTGATCATGCAGATCGAACTTTT
TCATCAATTTCCAGAGCTTGGCGAAACAGTCAGCGTGATACCTCTGATATTAAGGAGTTGATCCCTGAATTTTATTATCTCCCTGAGATG
TTTGTCAACTTCAATAATTATAATCTTGGAGTGATGGATGATGGGACAGTAGTGTCTGATGTCGAACTTCCTCCTTGGGCCAAAACCTCA
GAAGAATTTGTTCACATAAACAGATTGGCCCTGGAGAGTGAATTTGTTTCCTGCCAGCTTCACCAATGGATTGATCTCATTTTTGGCTAT
AAACAGCAAGGACCAGAAGCTGTCCGAGCCCTCAATGTGTTCTATTACTTGACCTATGAAGGAGCTGTCAATCTGAATTCAATAACTGAT
CCTGTGTTGAGAGAGGCTGTTGAAGCTCAAATCCGAAGTTTTGGACAGACTCCTTCTCAACTACTCATAGAGCCCCATCCTCCCAGAGGT
TCTGCCATGCAAGTGAGTCCATTGATGTTCACAGACAAAGCCCAGCAGGATGTTATCATGGTCCTCAAGTTTCCCTCCAACTCCCCTGTT
ACTCACGTGGCAGCCAACACCCAGCCTGGTTTGGCAACTCCCGCTGTGATCACAGTCACTGCTAACAGGTTATTTGCGGTGAACAAATGG
CACAACCTTCCTGCTCATCAAGGTGCTGTACAAGACCAGCCATACCAGCTGCCAGTGGAAATCGATCCTCTCATAGCCAGCAATACAGGA
ATGCACAGGAGGCAAATCACTGACCTTTTAGACCAAAGTATTCAAGTGCATTCCCAGTGCTTTGTCATCACTTCAGACAACCGCTATATT
CTCGTCTGTGGCTTCTGGGATAAAAGTTTCAGAGTCTATTCTACAGACACAGGAAGATTGATCCAAGTGGTGTTTGGCCATTGGGATGTC
GTCACTTGCCTTGCTCGTTCTGAGTCATATATTGGGGGAAATTGCTACATTCTCTCAGGGTCACGTGATGCAACTCTTTTGCTGTGGTAT
TGGAATGGAAAATGCAGTGGGATTGGAGATAACCCAGGCAGTGAGACTGCTGCTCCTCGGGCCATTTTGACCGGCCATGACTATGAGGTC
ACATGTGCTGCGGTGTGTGCGGAGCTAGGCCTGGTGTTGAGTGGTTCACAAGAAGGACCATGTCTCATACATTCCATGAATGGAGACTTG
TTGAGGACCTTGGAGGGTCCTGAAAACTGCCTGAAACCAAAACTCATTCAGGCTTCAAGAGAGGGTCATTGTGTCATATTCTATGAAAAC
GGCCTCTTCTGTACATTCAGTGTGAATGGAAAACTCCAGGCCACGATGGAAACAGATGATAACATAAGAGCCATCCAGCTGAGCCGAGAT
GGGCAGTACCTGCTCACAGGAGGAGACAGAGGAGTGGTCGTGGTCCGGCAGGTGTCGGACCTCAAGCAGCTCTTTGCCTATCCAGGATGT
GACGCTGGAATCCGGGCCATGGCGCTGTCTTACGACCAGAGGTGCATCATTTCTGGCATGGCTTCAGGAAGCATTGTGCTATTTTACAAC
GACTTTAACCGGTGGCATCATGAATACCAAACCCGCTACTGATGGTGACAGCTGTACATCAACTCTGCCCCTAGGATGAGCAGAAGTACC
TGGAGCATCATTCTCTTCTACCACATCTGAATGTAACTTAAATTTGCTCAAAGAAGCAAAATATTTTTTAAAGTTATTAATAATTGCTAT
TTTTGTAGTCTTTGCTTGACTTTTTTGGGGGGGATTAGCAAAGCAGAAAACTGGCTGCTGGGTTCTGTAGTTTTAAAAAATCTATATTTT
TAGTCATAATGAGAAGTCTATTTTCACCAATTATGGAAACATACAGTGGAGCAAGTAAACCACTTATTCCAGCTATAATATTATGAAGAA
CATTTCCCATGCATCTACAAGCTTGAGAAATAGGATTTTCACAGTGGGGAAGTGGGTTACAATATTGGAATAGGAAAATTTGATGCTGTA
ATTTGGGTCCTGTATTTTTCCAAACAACTGTGCTTCTTCAGCACTAATATTTCTGGGATTTAAATAGTAATGTTTAAATTATGGTAAATG
TAATTTAAAACATCTCAATTAAGTCTGTCTATCAATATTGTTCTTCAAGCATGTTTTAGACCTAGAAAAGTATGGTTTGGGGGAGGCTAT
TTTATTGTGTGGTTAGCACAAGGAATCTAATTTATAGCAAGTGTGAAATAGTTACCATTTTTTCCTGATCTGTCATCTTCATAGCACAAC
AAAACGAAATGATGGAAATGCTCTTGAGCTCACAACATTTGTTTTTCTTTTAAAGTAAATGCAAGTACCAAAGCTCACTACTGCGGTTTG
CCTGTGCCTGGACAATGAGGCGGAGCCACTGTTGTTTTGTTGGGGCACCCCCTTCCCTCCCCGGGTTTGCAAATAGAGGCTACCGGGTGC
TGTATTCAGCAACACCTGTTTTACTATTTGTTATTAAACTATCATCTCCACCTTCCTTTTGATTAGCAATTTGTACTAAGAAACGAAACA
ATGTTATTTGGTGGTGTATAATTCTACTTTTCTAGTAGATTACTGTGTGGAATTCTGTGAAAAATATTTGAGAAAAGGCCTGTATTGCAT
AAATAAATTCTTTGTATGTTGTGAACTTTGATCTCTATTTCTCTTGCAACAGACTTCAAGTGGTCCCTCTTTTTTTCCTACACACTCAGC
TCTTCTCTAAAAGCAAGGATTTGGAATGAACAATTCAGTTTGACAGAAAAAGCTGAATAAAATGGCATCTGTAATTGAATTGTTGGAAAT

>In-frame_ENST00000486715_ENST00000535741_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(amino acids)=2054AA_start in transcript=357_stop in transcript=6521
MRLLGAAAVAALGRGRAPASLGWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMD
SMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMG
SNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGQIVRYGEIPAELRAAATDHRQELIECVANSDEQLGEMFLE
EKIPSISDLKLAIRRATLKRSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKILMNSSRDNSHPFVGLAFKL
EVGRFGQLTYVRSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTFTDKANSGLSMESIHVPDPV
ISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHK
KQSGGAGQYGKVIGVLEPLDPEDYTKLEFSDETFGSNIPKQFVPAVEKHELENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEI
EAEKSMSSGGILRQCLRLVCAVAVRNCLECQQHSQLKTRGDKALKPMHSLIPLGKSAAKSPVDIVTGGISPVRDLDRLLQDMDINRLRAV
VFRDIEDSKQAQFLALAVVYFISVLMVSKYRDILEPQNERHSQSCTETGSENENVSLSEITPAAFSTLTTASVEESESTSSARRRDSGIG
EETATGLGSHVEVTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDRGNDLDTKATPSVSVSKNVNVKDILRSLVNIPADGVTVDPA
LLPPACLGALGDLSVEQPVQFRSFDRSVIVAAKKSAVSPSTFNTSIPTNAVSVVSSVDSAQASDMGGESPGSRSSNAKLPSVPTVDSVSQ
DPVSNMSITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELV
NEGRLLSQTMKDHLVRVANEAEFILSRQRAEDIHRHAEFESLCAQYSADKREDEKMCDHLIRAAKYRDHVTATQLIQKIINILTDKHGAW
GNSAVSRPLEFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEHATDEDILAKGKQSIRSQALGNQNSENEILLEGDDDTLSSVDEK
DLENLAGPVSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTEIRSIFSRRYLLQNTALEIFMAN
RVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRISLASPRQLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWV
ITNYESEELDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRT
FSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFG
YKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQVSPLMFTDKAQQDVIMVLKFPSNSP
VTHVAANTQPGLATPAVITVTANRLFAVNKWHNLPAHQGAVQDQPYQLPVEIDPLIASNTGMHRRQITDLLDQSIQVHSQCFVITSDNRY
ILVCGFWDKSFRVYSTDTGRLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWYWNGKCSGIGDNPGSETAAPRAILTGHDYE
VTCAAVCAELGLVLSGSQEGPCLIHSMNGDLLRTLEGPENCLKPKLIQASREGHCVIFYENGLFCTFSVNGKLQATMETDDNIRAIQLSR

--------------------------------------------------------------
>In-frame_ENST00000486715_ENST00000510413_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(transcript)=7710nt_BP=2121nt
TTCTGTATCTTCATACAGAGGTAATATTTAAAAAAGAAGACGAAGACAAAAGGACTCCCTTCCCTCACCCATATACCTATGCCGTCTTAC
TGGGAGCAAACACTTCTTTAGCTCCGCAAAGCGATTGCACTTTCTCTTCCAAGTCGGCAGACGGCGCGCGAGCAGCGTAGGCACTGCTCC
GCCTCCAATCCAGTTGCTCTTCTTTCTTTTCCTCACTCTCTTTTTCCTCGCGTCCTTTGCCCCGGAAGTGCTCTTACAACATTGGCTGCC
GGCGTGACTTTGACCGCTTCCCGGTGCGTTACCGGCAGCTGAACCCACCCGGCGCCACGGGACTTTGACGCGTGCTCTGCGCTTGCCATG
AGACTCCTGGGAGCTGCAGCCGTCGCGGCTCTGGGGCGCGGAAGGGCCCCCGCCTCCCTAGGCTGGCAGAGGAAGCAGGTTAATTGGAAG
GCCTGCCGATGGTCTTCATCAGGGGTGATTCCTAATGAAAAAATACGAAATATTGGAATCTCAGCTCACATTGATTCTGGGAAAACTACA
TTAACAGAACGAGTCCTTTACTACACTGGCAGAATTGCAAAGATGCATGAGGTGAAAGGTAAAGATGGAGTTGGTGCTGTCATGGATTCC
ATGGAACTAGAGAGACAAAGAGGAATCACTATTCAGTCAGCAGCCACTTACACCATGTGGAAAGATGTCAATATTAACATTATAGATACT
CCTGGGCATGTGGACTTCACAATAGAAGTGGAAAGGGCCCTGAGAGTGTTGGATGGTGCAGTCCTTGTTCTCTGTGCTGTTGGAGGGGTA
CAGTGCCAGACCATGACTGTCAATCGTCAGATGAAGCGCTACAACGTTCCGTTTCTAACTTTTATTAACAAATTGGACCGAATGGGCTCC
AACCCAGCCAGGGCCCTGCAGCAAATGAGGTCTAAACTAAATCATAATGCAGCGTTTATGCAGATACCCATGGGTTTGGAGGGTAATTTT
AAAGGTATTGTAGATCTTATTGAGGAACGAGCCATCTATTTTGATGGAGACTTTGGTCAGATTGTTCGATATGGTGAGATTCCAGCTGAA
TTAAGGGCGGCGGCCACTGACCACCGGCAGGAGCTAATTGAATGTGTTGCCAATTCAGATGAACAGCTTGGTGAGATGTTTCTGGAAGAA
AAAATCCCCTCGATTTCTGATTTAAAGCTAGCAATTCGAAGAGCTACTCTGAAAAGATCATTTACTCCTGTATTTTTGGGAAGCGCCTTG
AAGAACAAAGGAGTTCAGCCTCTTTTAGATGCTGTTTTAGAATACCTCCCAAATCCATCTGAAGTCCAGAACTATGCTATTCTCAATAAA
GAGGATGACTCAAAAGAGAAAACCAAAATCCTAATGAACTCCAGTAGAGACAATTCCCACCCATTTGTAGGCCTGGCTTTTAAACTGGAG
GTAGGTCGATTTGGACAATTAACTTATGTTCGCAGTTATCAGGGAGAGCTAAAGAAGGGTGACACCATCTATAACACAAGGACAAGAAAG
AAAGTACGGTTGCAACGGCTGGCTCGCATGCATGCCGACATGATGGAGGATGTTGAGGAAGTATATGCCGGAGACATCTGTGCATTGTTT
GGCATTGACTGTGCTAGTGGAGACACATTCACAGACAAAGCCAACAGCGGCCTTTCTATGGAGTCAATTCATGTTCCTGATCCTGTCATT
TCAATAGCAATGAAGCCTTCTAACAAGAACGATCTGGAAAAATTTTCAAAAGGTATTGGCAGGTTTACAAGAGAAGATCCCACATTTAAA
GTATACTTTGACACTGAGAACAAAGAGACAGTTATATCTGGAATGGGAGAATTACACCTGGAAATCTATGCTCAGAGGCTGGAAAGAGAG
TATGGCTGTCCTTGTATCACAGGAAAGCCAAAAGTTGCCTTTCGAGAGACCATTACTGCCCCTGTCCCGTTTGACTTTACACATAAAAAA
CAATCAGGTGGTGCAGGCCAGTATGGAAAAGTAATAGGTGTCCTGGAGCCTCTGGACCCAGAGGACTACACTAAATTGGAATTTTCAGAT
GAAACATTCGGATCAAATATTCCAAAGCAGTTTGTGCCTGCTGTAGAAAAGCATGAACTGGAAAATATTGAACCTACTCAAGGCCTTTCA
ATAGAAGCCTCTGTGACATTTTTGCAGAGGCTAATTAGCCTTGTGGATGTGCTTATATTTGCAAGTTCTCTTGGCTTTACTGAAATTGAA
GCTGAAAAAAGTATGTCATCTGGAGGAATTTTGCGGCAGTGTCTCCGACTAGTTTGTGCAGTCGCAGTAAGGAATTGCTTGGAGTGTCAA
CAGCATTCACAACTGAAAACTAGGGGAGATAAAGCCTTGAAACCAATGCATAGCCTTATTCCTTTAGGGAAATCTGCAGCGAAGAGCCCA
GTGGACATTGTGACTGGCGGTATATCTCCAGTAAGAGATCTTGACAGGCTTCTACAGGACATGGATATTAATCGGCTTAGGGCAGTTGTT
TTCAGAGACATAGAGGATAGCAAACAAGCTCAATTTTTAGCCTTGGCAGTAGTATACTTTATCTCTGTTCTTATGGTCTCCAAGTACAGA
GACATTTTGGAACCCCAAAATGAAAGGCATAGCCAGTCATGTACAGAAACTGGCAGTGAAAATGAGAATGTATCACTCTCTGAAATCACA
CCAGCAGCATTCAGCACTTTAACTACGGCATCAGTGGAAGAATCTGAAAGCACATCATCTGCTCGAAGGAGGGACTCAGGCATTGGGGAA
GAAACAGCCACTGGTTTAGGAAGCCATGTGGAAGTAACTCCTCACACAGCACCTCCTGGTGTCAGTGCAGGCCCAGATGCAATCAGCGAG
GTGCTATCTACTCTTTCTTTAGAAGTCAATAAGTCTCCGGAAACCAAAAATGATAGAGGAAATGACTTGGACACTAAGGCTACACCGTCA
GTTTCAGTTTCAAAAAACGTCAATGTGAAAGACATTCTCCGAAGCTTGGTTAACATACCAGCAGATGGAGTCACAGTGGATCCTGCCCTT
CTGCCACCAGCCTGCCTTGGAGCCCTTGGTGATCTATCTGTGGAACAACCCGTGCAGTTCAGATCTTTTGACAGAAGTGTCATTGTTGCA
GCAAAAAAGTCAGCAGTCTCACCTTCCACCTTTAATACAAGCATACCTACCAATGCTGTCAGTGTGGTTTCCTCAGTAGATTCAGCCCAA
GCCTCAGATATGGGAGGAGAATCACCAGGCAGTAGATCATCTAATGCAAAATTGCCCTCAGTTCCAACAGTTGATTCAGTTTCACAAGAT
CCGGTTTCAAATATGAGTATTACAGAGAGGCTTGAACACGCTTTGGAAAAGGCAGCTCCTCTCCTTCGTGAGATTTTTGTGGATTTTGCA
CCTTTTCTTTCTCGGACACTTTTGGGTAGCCATGGACAAGAACTGCTTATAGAAGGAACAAGTCTGGTTTGCATGAAGTCGAGTAGTTCA
GTTGTGGAATTGGTTATGCTACTGTGTTCTCAGGAGTGGCAAAATTCTATTCAGAAGAATGCAGGCCTTGCTTTTATCGAACTTGTCAAT
GAAGGAAGGTTGCTTAGCCAGACAATGAAGGATCATCTAGTAAGAGTAGCAAATGAAGCTGAATTTATCCTGAGCAGGCAGAGAGCAGAA
GATATTCACAGACATGCGGAATTTGAGTCACTGTGTGCCCAGTATTCTGCAGACAAACGAGAAGATGAGAAGATGTGTGATCATTTGATA
AGAGCAGCAAAATATCGTGACCACGTGACAGCAACTCAACTAATCCAGAAAATTATCAACATTCTCACAGACAAGCATGGAGCCTGGGGA
AATTCTGCAGTGAGTCGTCCTCTTGAGTTCTGGCGCCTTGACTACTGGGAAGATGACTTGCGGCGCCGGCGACGATTTGTGCGTAACCCT
CTAGGATCGACACATCCTGAAGCGACACTAAAAACAGCCGTGGAACATGCCACAGATGAAGATATCCTTGCTAAAGGAAAACAGTCCATC
AGGAGTCAGGCTTTAGGAAATCAGAACTCAGAAAACGAGATCCTCCTGGAAGGCGATGATGATACTCTGTCATCCGTGGATGAGAAAGAT
TTAGAGAATCTTGCCGGTCCTGTTAGCCTGAGCACACCAGCTCAGCTTGTGGCCCCCTCTGTTGTAGTAAAGGGCACTCTTTCTGTCACC
TCCTCCGAACTCTATTTTGAGGTGGATGAAGAGGATCCTAACTTCAAAAAAATCGACCCCAAGATCTTGGCATATACAGAAGGGCTGCAT
GGAAAATGGCTGTTCACAGAGATACGATCAATCTTTTCTCGTCGTTATCTTTTGCAAAATACAGCCCTGGAGATCTTTATGGCAAACAGA
GTTGCTGTGATGTTCAACTTCCCAGACCCTGCAACAGTAAAGAAAGTGGTTAACTATCTACCTCGTGTTGGCGTTGGAACAAGTTTTGGA
TTGCCTCAAACCAGACGTATTTCATTAGCTAGTCCACGTCAGCTTTTTAAGGCTTCTAATATGACCCAGCGATGGCAACACAGAGAGATA
TCTAATTTTGAGTACTTGATGTTTCTCAACACGATAGCAGGACGGAGTTATAATGACTTAAATCAGTATCCAGTGTTTCCTTGGGTCATC
ACTAATTATGAATCAGAAGAACTGGATCTTACCTTGCCCACCAACTTCAGAGATTTGTCCAAGCCAATAGGAGCTCTGAACCCAAAAAGA
GCAGCATTCTTCGCTGAGCGTTATGAATCATGGGAAGATGATCAAGTTCCAAAGTTTCACTATGGTACTCATTACTCAACTGCAAGTTTT
GTTCTTGCATGGCTGCTAAGAATAGAACCCTTTACAACTTATTTCCTAAATTTGCAAGGAGGCAAATTTGATCATGCAGATCGAACTTTT
TCATCAATTTCCAGAGCTTGGCGAAACAGTCAGCGTGATACCTCTGATATTAAGGAGTTGATCCCTGAATTTTATTATCTCCCTGAGATG
TTTGTCAACTTCAATAATTATAATCTTGGAGTGATGGATGATGGGACAGTAGTGTCTGATGTCGAACTTCCTCCTTGGGCCAAAACCTCA
GAAGAATTTGTTCACATAAACAGATTGGCCCTGGAGAGTGAATTTGTTTCCTGCCAGCTTCACCAATGGATTGATCTCATTTTTGGCTAT
AAACAGCAAGGACCAGAAGCTGTCCGAGCCCTCAATGTGTTCTATTACTTGACCTATGAAGGAGCTGTCAATCTGAATTCAATAACTGAT
CCTGTGTTGAGAGAGGCTGTTGAAGCTCAAATCCGAAGTTTTGGACAGACTCCTTCTCAACTACTCATAGAGCCCCATCCTCCCAGAGGT
TCTGCCATGCAAGTGAGTCCATTGATGTTCACAGACAAAGCCCAGCAGGATGTTATCATGGTCCTCAAGTTTCCCTCCAACTCCCCTGTT
ACTCACGTGGCAGCCAACACCCAGCCTGGTTTGGCAACTCCCGCTGTGATCACAGTCACTGCTAACAGGTTATTTGCGGTGAACAAATGG
CACAACCTTCCTGCTCATCAAGGTGCTGTACAAGACCAGCCATACCAGCTGCCAGTGGAAATCGATCCTCTCATAGCCAGCAATACAGGA
ATGCACAGGAGGCAAATCACTGACCTTTTAGACCAAAGTATTCAAGTGCATTCCCAGTGCTTTGTCATCACTTCAGACAACCGCTATATT
CTCGTCTGTGGCTTCTGGGATAAAAGTTTCAGAGTCTATTCTACAGACACAGGAAGATTGATCCAAGTGGTGTTTGGCCATTGGGATGTC
GTCACTTGCCTTGCTCGTTCTGAGTCATATATTGGGGGAAATTGCTACATTCTCTCAGGGTCACGTGATGCAACTCTTTTGCTGTGGTAT
TGGAATGGAAAATGCAGTGGGATTGGAGATAACCCAGGTGAGACTGCTGCTCCTCGGGCCATTTTGACCGGCCATGACTATGAGGTCACA
TGTGCTGCGGTGTGTGCGGAGCTAGGCCTGGTGTTGAGTGGTTCACAAGAAGGACCATGTCTCATACATTCCATGAATGGAGACTTGTTG
AGGACCTTGGAGGGTCCTGAAAACTGCCTGAAACCAAAACTCATTCAGGCTTCAAGAGAGGGTCATTGTGTCATATTCTATGAAAACGGC
CTCTTCTGTACATTCAGTGTGAATGGAAAACTCCAGGCCACGATGGAAACAGATGATAACATAAGAGCCATCCAGCTGAGCCGAGATGGG
CAGTACCTGCTCACAGGAGGAGACAGAGGAGTGGTCGTGGTCCGGCAGGTGTCGGACCTCAAGCAGCTCTTTGCCTATCCAGGATGTGAC
GCTGGAATCCGGGCCATGGCGCTGTCTTACGACCAGAGGTGCATCATTTCTGGCATGGCTTCAGGAAGCATTGTGCTATTTTACAACGAC
TTTAACCGGTGGCATCATGAATACCAAACCCGCTACTGATGGTGACAGCTGTACATCAACTCTGCCCCTAGGATGAGCAGAAGTACCTGG
AGCATCATTCTCTTCTACCACATCTGAATGTAACTTAAATTTGCTCAAAGAAGCAAAATATTTTTTAAAGTTATTAATAATTGCTATTTT
TGTAGTCTTTGCTTGACTTTTTTGGGGGGGATTAGCAAAGCAGAAAACTGGCTGCTGGGTTCTGTAGTTTTAAAAAATCTATATTTTTAG
TCATAATGAGAAGTCTATTTTCACCAATTATGGAAACATACAGTGGAGCAAGTAAACCACTTATTCCAGCTATAATATTATGAAGAACAT
TTCCCATGCATCTACAAGCTTGAGAAATAGGATTTTCACAGTGGGGAAGTGGGTTACAATATTGGAATAGGAAAATTTGATGCTGTAATT
TGGGTCCTGTATTTTTCCAAACAACTGTGCTTCTTCAGCACTAATATTTCTGGGATTTAAATAGTAATGTTTAAATTATGGTAAATGTAA
TTTAAAACATCTCAATTAAGTCTGTCTATCAATATTGTTCTTCAAGCATGTTTTAGACCTAGAAAAGTATGGTTTGGGGGAGGCTATTTT
ATTGTGTGGTTAGCACAAGGAATCTAATTTATAGCAAGTGTGAAATAGTTACCATTTTTTCCTGATCTGTCATCTTCATAGCACAACAAA
ACGAAATGATGGAAATGCTCTTGAGCTCACAACATTTGTTTTTCTTTTAAAGTAAATGCAAGTACCAAAGCTCACTACTGCGGTTTGCCT
GTGCCTGGACAATGAGGCGGAGCCACTGTTGTTTTGTTGGGGCACCCCCTTCCCTCCCCGGGTTTGCAAATAGAGGCTACCGGGTGCTGT
ATTCAGCAACACCTGTTTTACTATTTGTTATTAAACTATCATCTCCACCTTCCTTTTGATTAGCAATTTGTACTAAGAAACGAAACAATG
TTATTTGGTGGTGTATAATTCTACTTTTCTAGTAGATTACTGTGTGGAATTCTGTGAAAAATATTTGAGAAAAGGCCTGTATTGCATAAA
TAAATTCTTTGTATGTTGTGAACTTTGATCTCTATTTCTCTTGCAACAGACTTCAAGTGGTCCCTCTTTTTTTCCTACACACTCAGCTCT

>In-frame_ENST00000486715_ENST00000510413_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(amino acids)=2053AA_start in transcript=357_stop in transcript=6518
MRLLGAAAVAALGRGRAPASLGWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMD
SMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMG
SNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGQIVRYGEIPAELRAAATDHRQELIECVANSDEQLGEMFLE
EKIPSISDLKLAIRRATLKRSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKILMNSSRDNSHPFVGLAFKL
EVGRFGQLTYVRSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTFTDKANSGLSMESIHVPDPV
ISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHK
KQSGGAGQYGKVIGVLEPLDPEDYTKLEFSDETFGSNIPKQFVPAVEKHELENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEI
EAEKSMSSGGILRQCLRLVCAVAVRNCLECQQHSQLKTRGDKALKPMHSLIPLGKSAAKSPVDIVTGGISPVRDLDRLLQDMDINRLRAV
VFRDIEDSKQAQFLALAVVYFISVLMVSKYRDILEPQNERHSQSCTETGSENENVSLSEITPAAFSTLTTASVEESESTSSARRRDSGIG
EETATGLGSHVEVTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDRGNDLDTKATPSVSVSKNVNVKDILRSLVNIPADGVTVDPA
LLPPACLGALGDLSVEQPVQFRSFDRSVIVAAKKSAVSPSTFNTSIPTNAVSVVSSVDSAQASDMGGESPGSRSSNAKLPSVPTVDSVSQ
DPVSNMSITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELV
NEGRLLSQTMKDHLVRVANEAEFILSRQRAEDIHRHAEFESLCAQYSADKREDEKMCDHLIRAAKYRDHVTATQLIQKIINILTDKHGAW
GNSAVSRPLEFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEHATDEDILAKGKQSIRSQALGNQNSENEILLEGDDDTLSSVDEK
DLENLAGPVSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTEIRSIFSRRYLLQNTALEIFMAN
RVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRISLASPRQLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWV
ITNYESEELDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRT
FSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFG
YKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQVSPLMFTDKAQQDVIMVLKFPSNSP
VTHVAANTQPGLATPAVITVTANRLFAVNKWHNLPAHQGAVQDQPYQLPVEIDPLIASNTGMHRRQITDLLDQSIQVHSQCFVITSDNRY
ILVCGFWDKSFRVYSTDTGRLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWYWNGKCSGIGDNPGETAAPRAILTGHDYEV
TCAAVCAELGLVLSGSQEGPCLIHSMNGDLLRTLEGPENCLKPKLIQASREGHCVIFYENGLFCTFSVNGKLQATMETDDNIRAIQLSRD

--------------------------------------------------------------
>In-frame_ENST00000478576_ENST00000535741_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(transcript)=7665nt_BP=1984nt
CTCTTACAACATTGGCTGCCGGCGTGACTTTGACCGCTTCCCGGTGCGTTACCGGCAGCTGAACCCACCCGGCGCCACGGGACTTTGACG
CGTGCTCTGCGCTTGCCATGAGACTCCTGGGAGCTGCAGCCGTCGCGGCTCTGGGGCGCGGAAGGGCCCCCGCCTCCCTAGGCTGGCAGA
GGAAGCAGGTTAATTGGAAGGCCTGCCGATGGTCTTCATCAGGGGTGATTCCTAATGAAAAAATACGAAATATTGGAATCTCAGCTCACA
TTGATTCTGGGAAAACTACATTAACAGAACGAGTCCTTTACTACACTGGCAGAATTGCAAAGATGCATGAGGTGAAAGGTAAAGATGGAG
TTGGTGCTGTCATGGATTCCATGGAACTAGAGAGACAAAGAGGAATCACTATTCAGTCAGCAGCCACTTACACCATGTGGAAAGATGTCA
ATATTAACATTATAGATACTCCTGGGCATGTGGACTTCACAATAGAAGTGGAAAGGGCCCTGAGAGTGTTGGATGGTGCAGTCCTTGTTC
TCTGTGCTGTTGGAGGGGTACAGTGCCAGACCATGACTGTCAATCGTCAGATGAAGCGCTACAACGTTCCGTTTCTAACTTTTATTAACA
AATTGGACCGAATGGGCTCCAACCCAGCCAGGGCCCTGCAGCAAATGAGGTCTAAACTAAATCATAATGCAGCGTTTATGCAGATACCCA
TGGGTTTGGAGGGTAATTTTAAAGGTATTGTAGATCTTATTGAGGAACGAGCCATCTATTTTGATGGAGACTTTGGTCAGATTGTTCGAT
ATGGTGAGATTCCAGCTGAATTAAGGGCGGCGGCCACTGACCACCGGCAGGAGCTAATTGAATGTGTTGCCAATTCAGATGAACAGCTTG
GTGAGATGTTTCTGGAAGAAAAAATCCCCTCGATTTCTGATTTAAAGCTAGCAATTCGAAGAGCTACTCTGAAAAGATCATTTACTCCTG
TATTTTTGGGAAGCGCCTTGAAGAACAAAGGAGTTCAGCCTCTTTTAGATGCTGTTTTAGAATACCTCCCAAATCCATCTGAAGTCCAGA
ACTATGCTATTCTCAATAAAGAGGATGACTCAAAAGAGAAAACCAAAATCCTAATGAACTCCAGTAGAGACAATTCCCACCCATTTGTAG
GCCTGGCTTTTAAACTGGAGGTAGGTCGATTTGGACAATTAACTTATGTTCGCAGTTATCAGGGAGAGCTAAAGAAGGGTGACACCATCT
ATAACACAAGGACAAGAAAGAAAGTACGGTTGCAACGGCTGGCTCGCATGCATGCCGACATGATGGAGGATGTTGAGGAAGTATATGCCG
GAGACATCTGTGCATTGTTTGGCATTGACTGTGCTAGTGGAGACACATTCACAGACAAAGCCAACAGCGGCCTTTCTATGGAGTCAATTC
ATGTTCCTGATCCTGTCATTTCAATAGCAATGAAGCCTTCTAACAAGAACGATCTGGAAAAATTTTCAAAAGGTATTGGCAGGTTTACAA
GAGAAGATCCCACATTTAAAGTATACTTTGACACTGAGAACAAAGAGACAGTTATATCTGGAATGGGAGAATTACACCTGGAAATCTATG
CTCAGAGGCTGGAAAGAGAGTATGGCTGTCCTTGTATCACAGGAAAGCCAAAAGTTGCCTTTCGAGAGACCATTACTGCCCCTGTCCCGT
AAATTTTTAAAAAAGTGTTTTTGCATTTTTACTTACTAAAAACAGTTTATCAGGTATTAAATCATACTTTGTCTTCCATCATGTTGTCTA
TCACAGTTTGTTTTAGTTACAGTCCTGTTTCTCTGATTGTTAAGCTTTCCATCTGATTTAGAATCTCTAATTCATTAAGCAGAAGAGCTG
TAAATCCATGCTGTGACAATGATGGGAAATTATTATGTTTCTGAATCATAGTTATATTTTTCTTAATAAATTGAAACTACTGTATTGATT
GTAACATGAACTGGAAAATATTGAACCTACTCAAGGCCTTTCAATAGAAGCCTCTGTGACATTTTTGCAGAGGCTAATTAGCCTTGTGGA
TGTGCTTATATTTGCAAGTTCTCTTGGCTTTACTGAAATTGAAGCTGAAAAAAGTATGTCATCTGGAGGAATTTTGCGGCAGTGTCTCCG
ACTAGTTTGTGCAGTCGCAGTAAGGAATTGCTTGGAGTGTCAACAGCATTCACAACTGAAAACTAGGGGAGATAAAGCCTTGAAACCAAT
GCATAGCCTTATTCCTTTAGGGAAATCTGCAGCGAAGAGCCCAGTGGACATTGTGACTGGCGGTATATCTCCAGTAAGAGATCTTGACAG
GCTTCTACAGGACATGGATATTAATCGGCTTAGGGCAGTTGTTTTCAGAGACATAGAGGATAGCAAACAAGCTCAATTTTTAGCCTTGGC
AGTAGTATACTTTATCTCTGTTCTTATGGTCTCCAAGTACAGAGACATTTTGGAACCCCAAAATGAAAGGCATAGCCAGTCATGTACAGA
AACTGGCAGTGAAAATGAGAATGTATCACTCTCTGAAATCACACCAGCAGCATTCAGCACTTTAACTACGGCATCAGTGGAAGAATCTGA
AAGCACATCATCTGCTCGAAGGAGGGACTCAGGCATTGGGGAAGAAACAGCCACTGGTTTAGGAAGCCATGTGGAAGTAACTCCTCACAC
AGCACCTCCTGGTGTCAGTGCAGGCCCAGATGCAATCAGCGAGGTGCTATCTACTCTTTCTTTAGAAGTCAATAAGTCTCCGGAAACCAA
AAATGATAGAGGAAATGACTTGGACACTAAGGCTACACCGTCAGTTTCAGTTTCAAAAAACGTCAATGTGAAAGACATTCTCCGAAGCTT
GGTTAACATACCAGCAGATGGAGTCACAGTGGATCCTGCCCTTCTGCCACCAGCCTGCCTTGGAGCCCTTGGTGATCTATCTGTGGAACA
ACCCGTGCAGTTCAGATCTTTTGACAGAAGTGTCATTGTTGCAGCAAAAAAGTCAGCAGTCTCACCTTCCACCTTTAATACAAGCATACC
TACCAATGCTGTCAGTGTGGTTTCCTCAGTAGATTCAGCCCAAGCCTCAGATATGGGAGGAGAATCACCAGGCAGTAGATCATCTAATGC
AAAATTGCCCTCAGTTCCAACAGTTGATTCAGTTTCACAAGATCCGGTTTCAAATATGAGTATTACAGAGAGGCTTGAACACGCTTTGGA
AAAGGCAGCTCCTCTCCTTCGTGAGATTTTTGTGGATTTTGCACCTTTTCTTTCTCGGACACTTTTGGGTAGCCATGGACAAGAACTGCT
TATAGAAGGAACAAGTCTGGTTTGCATGAAGTCGAGTAGTTCAGTTGTGGAATTGGTTATGCTACTGTGTTCTCAGGAGTGGCAAAATTC
TATTCAGAAGAATGCAGGCCTTGCTTTTATCGAACTTGTCAATGAAGGAAGGTTGCTTAGCCAGACAATGAAGGATCATCTAGTAAGAGT
AGCAAATGAAGCTGAATTTATCCTGAGCAGGCAGAGAGCAGAAGATATTCACAGACATGCGGAATTTGAGTCACTGTGTGCCCAGTATTC
TGCAGACAAACGAGAAGATGAGAAGATGTGTGATCATTTGATAAGAGCAGCAAAATATCGTGACCACGTGACAGCAACTCAACTAATCCA
GAAAATTATCAACATTCTCACAGACAAGCATGGAGCCTGGGGAAATTCTGCAGTGAGTCGTCCTCTTGAGTTCTGGCGCCTTGACTACTG
GGAAGATGACTTGCGGCGCCGGCGACGATTTGTGCGTAACCCTCTAGGATCGACACATCCTGAAGCGACACTAAAAACAGCCGTGGAACA
TGCCACAGATGAAGATATCCTTGCTAAAGGAAAACAGTCCATCAGGAGTCAGGCTTTAGGAAATCAGAACTCAGAAAACGAGATCCTCCT
GGAAGGCGATGATGATACTCTGTCATCCGTGGATGAGAAAGATTTAGAGAATCTTGCCGGTCCTGTTAGCCTGAGCACACCAGCTCAGCT
TGTGGCCCCCTCTGTTGTAGTAAAGGGCACTCTTTCTGTCACCTCCTCCGAACTCTATTTTGAGGTGGATGAAGAGGATCCTAACTTCAA
AAAAATCGACCCCAAGATCTTGGCATATACAGAAGGGCTGCATGGAAAATGGCTGTTCACAGAGATACGATCAATCTTTTCTCGTCGTTA
TCTTTTGCAAAATACAGCCCTGGAGATCTTTATGGCAAACAGAGTTGCTGTGATGTTCAACTTCCCAGACCCTGCAACAGTAAAGAAAGT
GGTTAACTATCTACCTCGTGTTGGCGTTGGAACAAGTTTTGGATTGCCTCAAACCAGACGTATTTCATTAGCTAGTCCACGTCAGCTTTT
TAAGGCTTCTAATATGACCCAGCGATGGCAACACAGAGAGATATCTAATTTTGAGTACTTGATGTTTCTCAACACGATAGCAGGACGGAG
TTATAATGACTTAAATCAGTATCCAGTGTTTCCTTGGGTCATCACTAATTATGAATCAGAAGAACTGGATCTTACCTTGCCCACCAACTT
CAGAGATTTGTCCAAGCCAATAGGAGCTCTGAACCCAAAAAGAGCAGCATTCTTCGCTGAGCGTTATGAATCATGGGAAGATGATCAAGT
TCCAAAGTTTCACTATGGTACTCATTACTCAACTGCAAGTTTTGTTCTTGCATGGCTGCTAAGAATAGAACCCTTTACAACTTATTTCCT
AAATTTGCAAGGAGGCAAATTTGATCATGCAGATCGAACTTTTTCATCAATTTCCAGAGCTTGGCGAAACAGTCAGCGTGATACCTCTGA
TATTAAGGAGTTGATCCCTGAATTTTATTATCTCCCTGAGATGTTTGTCAACTTCAATAATTATAATCTTGGAGTGATGGATGATGGGAC
AGTAGTGTCTGATGTCGAACTTCCTCCTTGGGCCAAAACCTCAGAAGAATTTGTTCACATAAACAGATTGGCCCTGGAGAGTGAATTTGT
TTCCTGCCAGCTTCACCAATGGATTGATCTCATTTTTGGCTATAAACAGCAAGGACCAGAAGCTGTCCGAGCCCTCAATGTGTTCTATTA
CTTGACCTATGAAGGAGCTGTCAATCTGAATTCAATAACTGATCCTGTGTTGAGAGAGGCTGTTGAAGCTCAAATCCGAAGTTTTGGACA
GACTCCTTCTCAACTACTCATAGAGCCCCATCCTCCCAGAGGTTCTGCCATGCAAGTGAGTCCATTGATGTTCACAGACAAAGCCCAGCA
GGATGTTATCATGGTCCTCAAGTTTCCCTCCAACTCCCCTGTTACTCACGTGGCAGCCAACACCCAGCCTGGTTTGGCAACTCCCGCTGT
GATCACAGTCACTGCTAACAGGTTATTTGCGGTGAACAAATGGCACAACCTTCCTGCTCATCAAGGTGCTGTACAAGACCAGCCATACCA
GCTGCCAGTGGAAATCGATCCTCTCATAGCCAGCAATACAGGAATGCACAGGAGGCAAATCACTGACCTTTTAGACCAAAGTATTCAAGT
GCATTCCCAGTGCTTTGTCATCACTTCAGACAACCGCTATATTCTCGTCTGTGGCTTCTGGGATAAAAGTTTCAGAGTCTATTCTACAGA
CACAGGAAGATTGATCCAAGTGGTGTTTGGCCATTGGGATGTCGTCACTTGCCTTGCTCGTTCTGAGTCATATATTGGGGGAAATTGCTA
CATTCTCTCAGGGTCACGTGATGCAACTCTTTTGCTGTGGTATTGGAATGGAAAATGCAGTGGGATTGGAGATAACCCAGGCAGTGAGAC
TGCTGCTCCTCGGGCCATTTTGACCGGCCATGACTATGAGGTCACATGTGCTGCGGTGTGTGCGGAGCTAGGCCTGGTGTTGAGTGGTTC
ACAAGAAGGACCATGTCTCATACATTCCATGAATGGAGACTTGTTGAGGACCTTGGAGGGTCCTGAAAACTGCCTGAAACCAAAACTCAT
TCAGGCTTCAAGAGAGGGTCATTGTGTCATATTCTATGAAAACGGCCTCTTCTGTACATTCAGTGTGAATGGAAAACTCCAGGCCACGAT
GGAAACAGATGATAACATAAGAGCCATCCAGCTGAGCCGAGATGGGCAGTACCTGCTCACAGGAGGAGACAGAGGAGTGGTCGTGGTCCG
GCAGGTGTCGGACCTCAAGCAGCTCTTTGCCTATCCAGGATGTGACGCTGGAATCCGGGCCATGGCGCTGTCTTACGACCAGAGGTGCAT
CATTTCTGGCATGGCTTCAGGAAGCATTGTGCTATTTTACAACGACTTTAACCGGTGGCATCATGAATACCAAACCCGCTACTGATGGTG
ACAGCTGTACATCAACTCTGCCCCTAGGATGAGCAGAAGTACCTGGAGCATCATTCTCTTCTACCACATCTGAATGTAACTTAAATTTGC
TCAAAGAAGCAAAATATTTTTTAAAGTTATTAATAATTGCTATTTTTGTAGTCTTTGCTTGACTTTTTTGGGGGGGATTAGCAAAGCAGA
AAACTGGCTGCTGGGTTCTGTAGTTTTAAAAAATCTATATTTTTAGTCATAATGAGAAGTCTATTTTCACCAATTATGGAAACATACAGT
GGAGCAAGTAAACCACTTATTCCAGCTATAATATTATGAAGAACATTTCCCATGCATCTACAAGCTTGAGAAATAGGATTTTCACAGTGG
GGAAGTGGGTTACAATATTGGAATAGGAAAATTTGATGCTGTAATTTGGGTCCTGTATTTTTCCAAACAACTGTGCTTCTTCAGCACTAA
TATTTCTGGGATTTAAATAGTAATGTTTAAATTATGGTAAATGTAATTTAAAACATCTCAATTAAGTCTGTCTATCAATATTGTTCTTCA
AGCATGTTTTAGACCTAGAAAAGTATGGTTTGGGGGAGGCTATTTTATTGTGTGGTTAGCACAAGGAATCTAATTTATAGCAAGTGTGAA
ATAGTTACCATTTTTTCCTGATCTGTCATCTTCATAGCACAACAAAACGAAATGATGGAAATGCTCTTGAGCTCACAACATTTGTTTTTC
TTTTAAAGTAAATGCAAGTACCAAAGCTCACTACTGCGGTTTGCCTGTGCCTGGACAATGAGGCGGAGCCACTGTTGTTTTGTTGGGGCA
CCCCCTTCCCTCCCCGGGTTTGCAAATAGAGGCTACCGGGTGCTGTATTCAGCAACACCTGTTTTACTATTTGTTATTAAACTATCATCT
CCACCTTCCTTTTGATTAGCAATTTGTACTAAGAAACGAAACAATGTTATTTGGTGGTGTATAATTCTACTTTTCTAGTAGATTACTGTG
TGGAATTCTGTGAAAAATATTTGAGAAAAGGCCTGTATTGCATAAATAAATTCTTTGTATGTTGTGAACTTTGATCTCTATTTCTCTTGC
AACAGACTTCAAGTGGTCCCTCTTTTTTTCCTACACACTCAGCTCTTCTCTAAAAGCAAGGATTTGGAATGAACAATTCAGTTTGACAGA
AAAAGCTGAATAAAATGGCATCTGTAATTGAATTGTTGGAAATGCCTTTTTTGCTCCTAAATTTTAAACATCATTAATAAAATAATGATT

>In-frame_ENST00000478576_ENST00000535741_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(amino acids)=1464AA_start in transcript=1990_stop in transcript=6384
MENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEIEAEKSMSSGGILRQCLRLVCAVAVRNCLECQQHSQLKTRGDKALKPMHSL
IPLGKSAAKSPVDIVTGGISPVRDLDRLLQDMDINRLRAVVFRDIEDSKQAQFLALAVVYFISVLMVSKYRDILEPQNERHSQSCTETGS
ENENVSLSEITPAAFSTLTTASVEESESTSSARRRDSGIGEETATGLGSHVEVTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDR
GNDLDTKATPSVSVSKNVNVKDILRSLVNIPADGVTVDPALLPPACLGALGDLSVEQPVQFRSFDRSVIVAAKKSAVSPSTFNTSIPTNA
VSVVSSVDSAQASDMGGESPGSRSSNAKLPSVPTVDSVSQDPVSNMSITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEG
TSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSQTMKDHLVRVANEAEFILSRQRAEDIHRHAEFESLCAQYSADK
REDEKMCDHLIRAAKYRDHVTATQLIQKIINILTDKHGAWGNSAVSRPLEFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEHATD
EDILAKGKQSIRSQALGNQNSENEILLEGDDDTLSSVDEKDLENLAGPVSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKID
PKILAYTEGLHGKWLFTEIRSIFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRISLASPRQLFKAS
NMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQVPKF
HYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVS
DVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPS
QLLIEPHPPRGSAMQVSPLMFTDKAQQDVIMVLKFPSNSPVTHVAANTQPGLATPAVITVTANRLFAVNKWHNLPAHQGAVQDQPYQLPV
EIDPLIASNTGMHRRQITDLLDQSIQVHSQCFVITSDNRYILVCGFWDKSFRVYSTDTGRLIQVVFGHWDVVTCLARSESYIGGNCYILS
GSRDATLLLWYWNGKCSGIGDNPGSETAAPRAILTGHDYEVTCAAVCAELGLVLSGSQEGPCLIHSMNGDLLRTLEGPENCLKPKLIQAS
REGHCVIFYENGLFCTFSVNGKLQATMETDDNIRAIQLSRDGQYLLTGGDRGVVVVRQVSDLKQLFAYPGCDAGIRAMALSYDQRCIISG

--------------------------------------------------------------
>In-frame_ENST00000478576_ENST00000510413_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(transcript)=7573nt_BP=1984nt
CTCTTACAACATTGGCTGCCGGCGTGACTTTGACCGCTTCCCGGTGCGTTACCGGCAGCTGAACCCACCCGGCGCCACGGGACTTTGACG
CGTGCTCTGCGCTTGCCATGAGACTCCTGGGAGCTGCAGCCGTCGCGGCTCTGGGGCGCGGAAGGGCCCCCGCCTCCCTAGGCTGGCAGA
GGAAGCAGGTTAATTGGAAGGCCTGCCGATGGTCTTCATCAGGGGTGATTCCTAATGAAAAAATACGAAATATTGGAATCTCAGCTCACA
TTGATTCTGGGAAAACTACATTAACAGAACGAGTCCTTTACTACACTGGCAGAATTGCAAAGATGCATGAGGTGAAAGGTAAAGATGGAG
TTGGTGCTGTCATGGATTCCATGGAACTAGAGAGACAAAGAGGAATCACTATTCAGTCAGCAGCCACTTACACCATGTGGAAAGATGTCA
ATATTAACATTATAGATACTCCTGGGCATGTGGACTTCACAATAGAAGTGGAAAGGGCCCTGAGAGTGTTGGATGGTGCAGTCCTTGTTC
TCTGTGCTGTTGGAGGGGTACAGTGCCAGACCATGACTGTCAATCGTCAGATGAAGCGCTACAACGTTCCGTTTCTAACTTTTATTAACA
AATTGGACCGAATGGGCTCCAACCCAGCCAGGGCCCTGCAGCAAATGAGGTCTAAACTAAATCATAATGCAGCGTTTATGCAGATACCCA
TGGGTTTGGAGGGTAATTTTAAAGGTATTGTAGATCTTATTGAGGAACGAGCCATCTATTTTGATGGAGACTTTGGTCAGATTGTTCGAT
ATGGTGAGATTCCAGCTGAATTAAGGGCGGCGGCCACTGACCACCGGCAGGAGCTAATTGAATGTGTTGCCAATTCAGATGAACAGCTTG
GTGAGATGTTTCTGGAAGAAAAAATCCCCTCGATTTCTGATTTAAAGCTAGCAATTCGAAGAGCTACTCTGAAAAGATCATTTACTCCTG
TATTTTTGGGAAGCGCCTTGAAGAACAAAGGAGTTCAGCCTCTTTTAGATGCTGTTTTAGAATACCTCCCAAATCCATCTGAAGTCCAGA
ACTATGCTATTCTCAATAAAGAGGATGACTCAAAAGAGAAAACCAAAATCCTAATGAACTCCAGTAGAGACAATTCCCACCCATTTGTAG
GCCTGGCTTTTAAACTGGAGGTAGGTCGATTTGGACAATTAACTTATGTTCGCAGTTATCAGGGAGAGCTAAAGAAGGGTGACACCATCT
ATAACACAAGGACAAGAAAGAAAGTACGGTTGCAACGGCTGGCTCGCATGCATGCCGACATGATGGAGGATGTTGAGGAAGTATATGCCG
GAGACATCTGTGCATTGTTTGGCATTGACTGTGCTAGTGGAGACACATTCACAGACAAAGCCAACAGCGGCCTTTCTATGGAGTCAATTC
ATGTTCCTGATCCTGTCATTTCAATAGCAATGAAGCCTTCTAACAAGAACGATCTGGAAAAATTTTCAAAAGGTATTGGCAGGTTTACAA
GAGAAGATCCCACATTTAAAGTATACTTTGACACTGAGAACAAAGAGACAGTTATATCTGGAATGGGAGAATTACACCTGGAAATCTATG
CTCAGAGGCTGGAAAGAGAGTATGGCTGTCCTTGTATCACAGGAAAGCCAAAAGTTGCCTTTCGAGAGACCATTACTGCCCCTGTCCCGT
AAATTTTTAAAAAAGTGTTTTTGCATTTTTACTTACTAAAAACAGTTTATCAGGTATTAAATCATACTTTGTCTTCCATCATGTTGTCTA
TCACAGTTTGTTTTAGTTACAGTCCTGTTTCTCTGATTGTTAAGCTTTCCATCTGATTTAGAATCTCTAATTCATTAAGCAGAAGAGCTG
TAAATCCATGCTGTGACAATGATGGGAAATTATTATGTTTCTGAATCATAGTTATATTTTTCTTAATAAATTGAAACTACTGTATTGATT
GTAACATGAACTGGAAAATATTGAACCTACTCAAGGCCTTTCAATAGAAGCCTCTGTGACATTTTTGCAGAGGCTAATTAGCCTTGTGGA
TGTGCTTATATTTGCAAGTTCTCTTGGCTTTACTGAAATTGAAGCTGAAAAAAGTATGTCATCTGGAGGAATTTTGCGGCAGTGTCTCCG
ACTAGTTTGTGCAGTCGCAGTAAGGAATTGCTTGGAGTGTCAACAGCATTCACAACTGAAAACTAGGGGAGATAAAGCCTTGAAACCAAT
GCATAGCCTTATTCCTTTAGGGAAATCTGCAGCGAAGAGCCCAGTGGACATTGTGACTGGCGGTATATCTCCAGTAAGAGATCTTGACAG
GCTTCTACAGGACATGGATATTAATCGGCTTAGGGCAGTTGTTTTCAGAGACATAGAGGATAGCAAACAAGCTCAATTTTTAGCCTTGGC
AGTAGTATACTTTATCTCTGTTCTTATGGTCTCCAAGTACAGAGACATTTTGGAACCCCAAAATGAAAGGCATAGCCAGTCATGTACAGA
AACTGGCAGTGAAAATGAGAATGTATCACTCTCTGAAATCACACCAGCAGCATTCAGCACTTTAACTACGGCATCAGTGGAAGAATCTGA
AAGCACATCATCTGCTCGAAGGAGGGACTCAGGCATTGGGGAAGAAACAGCCACTGGTTTAGGAAGCCATGTGGAAGTAACTCCTCACAC
AGCACCTCCTGGTGTCAGTGCAGGCCCAGATGCAATCAGCGAGGTGCTATCTACTCTTTCTTTAGAAGTCAATAAGTCTCCGGAAACCAA
AAATGATAGAGGAAATGACTTGGACACTAAGGCTACACCGTCAGTTTCAGTTTCAAAAAACGTCAATGTGAAAGACATTCTCCGAAGCTT
GGTTAACATACCAGCAGATGGAGTCACAGTGGATCCTGCCCTTCTGCCACCAGCCTGCCTTGGAGCCCTTGGTGATCTATCTGTGGAACA
ACCCGTGCAGTTCAGATCTTTTGACAGAAGTGTCATTGTTGCAGCAAAAAAGTCAGCAGTCTCACCTTCCACCTTTAATACAAGCATACC
TACCAATGCTGTCAGTGTGGTTTCCTCAGTAGATTCAGCCCAAGCCTCAGATATGGGAGGAGAATCACCAGGCAGTAGATCATCTAATGC
AAAATTGCCCTCAGTTCCAACAGTTGATTCAGTTTCACAAGATCCGGTTTCAAATATGAGTATTACAGAGAGGCTTGAACACGCTTTGGA
AAAGGCAGCTCCTCTCCTTCGTGAGATTTTTGTGGATTTTGCACCTTTTCTTTCTCGGACACTTTTGGGTAGCCATGGACAAGAACTGCT
TATAGAAGGAACAAGTCTGGTTTGCATGAAGTCGAGTAGTTCAGTTGTGGAATTGGTTATGCTACTGTGTTCTCAGGAGTGGCAAAATTC
TATTCAGAAGAATGCAGGCCTTGCTTTTATCGAACTTGTCAATGAAGGAAGGTTGCTTAGCCAGACAATGAAGGATCATCTAGTAAGAGT
AGCAAATGAAGCTGAATTTATCCTGAGCAGGCAGAGAGCAGAAGATATTCACAGACATGCGGAATTTGAGTCACTGTGTGCCCAGTATTC
TGCAGACAAACGAGAAGATGAGAAGATGTGTGATCATTTGATAAGAGCAGCAAAATATCGTGACCACGTGACAGCAACTCAACTAATCCA
GAAAATTATCAACATTCTCACAGACAAGCATGGAGCCTGGGGAAATTCTGCAGTGAGTCGTCCTCTTGAGTTCTGGCGCCTTGACTACTG
GGAAGATGACTTGCGGCGCCGGCGACGATTTGTGCGTAACCCTCTAGGATCGACACATCCTGAAGCGACACTAAAAACAGCCGTGGAACA
TGCCACAGATGAAGATATCCTTGCTAAAGGAAAACAGTCCATCAGGAGTCAGGCTTTAGGAAATCAGAACTCAGAAAACGAGATCCTCCT
GGAAGGCGATGATGATACTCTGTCATCCGTGGATGAGAAAGATTTAGAGAATCTTGCCGGTCCTGTTAGCCTGAGCACACCAGCTCAGCT
TGTGGCCCCCTCTGTTGTAGTAAAGGGCACTCTTTCTGTCACCTCCTCCGAACTCTATTTTGAGGTGGATGAAGAGGATCCTAACTTCAA
AAAAATCGACCCCAAGATCTTGGCATATACAGAAGGGCTGCATGGAAAATGGCTGTTCACAGAGATACGATCAATCTTTTCTCGTCGTTA
TCTTTTGCAAAATACAGCCCTGGAGATCTTTATGGCAAACAGAGTTGCTGTGATGTTCAACTTCCCAGACCCTGCAACAGTAAAGAAAGT
GGTTAACTATCTACCTCGTGTTGGCGTTGGAACAAGTTTTGGATTGCCTCAAACCAGACGTATTTCATTAGCTAGTCCACGTCAGCTTTT
TAAGGCTTCTAATATGACCCAGCGATGGCAACACAGAGAGATATCTAATTTTGAGTACTTGATGTTTCTCAACACGATAGCAGGACGGAG
TTATAATGACTTAAATCAGTATCCAGTGTTTCCTTGGGTCATCACTAATTATGAATCAGAAGAACTGGATCTTACCTTGCCCACCAACTT
CAGAGATTTGTCCAAGCCAATAGGAGCTCTGAACCCAAAAAGAGCAGCATTCTTCGCTGAGCGTTATGAATCATGGGAAGATGATCAAGT
TCCAAAGTTTCACTATGGTACTCATTACTCAACTGCAAGTTTTGTTCTTGCATGGCTGCTAAGAATAGAACCCTTTACAACTTATTTCCT
AAATTTGCAAGGAGGCAAATTTGATCATGCAGATCGAACTTTTTCATCAATTTCCAGAGCTTGGCGAAACAGTCAGCGTGATACCTCTGA
TATTAAGGAGTTGATCCCTGAATTTTATTATCTCCCTGAGATGTTTGTCAACTTCAATAATTATAATCTTGGAGTGATGGATGATGGGAC
AGTAGTGTCTGATGTCGAACTTCCTCCTTGGGCCAAAACCTCAGAAGAATTTGTTCACATAAACAGATTGGCCCTGGAGAGTGAATTTGT
TTCCTGCCAGCTTCACCAATGGATTGATCTCATTTTTGGCTATAAACAGCAAGGACCAGAAGCTGTCCGAGCCCTCAATGTGTTCTATTA
CTTGACCTATGAAGGAGCTGTCAATCTGAATTCAATAACTGATCCTGTGTTGAGAGAGGCTGTTGAAGCTCAAATCCGAAGTTTTGGACA
GACTCCTTCTCAACTACTCATAGAGCCCCATCCTCCCAGAGGTTCTGCCATGCAAGTGAGTCCATTGATGTTCACAGACAAAGCCCAGCA
GGATGTTATCATGGTCCTCAAGTTTCCCTCCAACTCCCCTGTTACTCACGTGGCAGCCAACACCCAGCCTGGTTTGGCAACTCCCGCTGT
GATCACAGTCACTGCTAACAGGTTATTTGCGGTGAACAAATGGCACAACCTTCCTGCTCATCAAGGTGCTGTACAAGACCAGCCATACCA
GCTGCCAGTGGAAATCGATCCTCTCATAGCCAGCAATACAGGAATGCACAGGAGGCAAATCACTGACCTTTTAGACCAAAGTATTCAAGT
GCATTCCCAGTGCTTTGTCATCACTTCAGACAACCGCTATATTCTCGTCTGTGGCTTCTGGGATAAAAGTTTCAGAGTCTATTCTACAGA
CACAGGAAGATTGATCCAAGTGGTGTTTGGCCATTGGGATGTCGTCACTTGCCTTGCTCGTTCTGAGTCATATATTGGGGGAAATTGCTA
CATTCTCTCAGGGTCACGTGATGCAACTCTTTTGCTGTGGTATTGGAATGGAAAATGCAGTGGGATTGGAGATAACCCAGGTGAGACTGC
TGCTCCTCGGGCCATTTTGACCGGCCATGACTATGAGGTCACATGTGCTGCGGTGTGTGCGGAGCTAGGCCTGGTGTTGAGTGGTTCACA
AGAAGGACCATGTCTCATACATTCCATGAATGGAGACTTGTTGAGGACCTTGGAGGGTCCTGAAAACTGCCTGAAACCAAAACTCATTCA
GGCTTCAAGAGAGGGTCATTGTGTCATATTCTATGAAAACGGCCTCTTCTGTACATTCAGTGTGAATGGAAAACTCCAGGCCACGATGGA
AACAGATGATAACATAAGAGCCATCCAGCTGAGCCGAGATGGGCAGTACCTGCTCACAGGAGGAGACAGAGGAGTGGTCGTGGTCCGGCA
GGTGTCGGACCTCAAGCAGCTCTTTGCCTATCCAGGATGTGACGCTGGAATCCGGGCCATGGCGCTGTCTTACGACCAGAGGTGCATCAT
TTCTGGCATGGCTTCAGGAAGCATTGTGCTATTTTACAACGACTTTAACCGGTGGCATCATGAATACCAAACCCGCTACTGATGGTGACA
GCTGTACATCAACTCTGCCCCTAGGATGAGCAGAAGTACCTGGAGCATCATTCTCTTCTACCACATCTGAATGTAACTTAAATTTGCTCA
AAGAAGCAAAATATTTTTTAAAGTTATTAATAATTGCTATTTTTGTAGTCTTTGCTTGACTTTTTTGGGGGGGATTAGCAAAGCAGAAAA
CTGGCTGCTGGGTTCTGTAGTTTTAAAAAATCTATATTTTTAGTCATAATGAGAAGTCTATTTTCACCAATTATGGAAACATACAGTGGA
GCAAGTAAACCACTTATTCCAGCTATAATATTATGAAGAACATTTCCCATGCATCTACAAGCTTGAGAAATAGGATTTTCACAGTGGGGA
AGTGGGTTACAATATTGGAATAGGAAAATTTGATGCTGTAATTTGGGTCCTGTATTTTTCCAAACAACTGTGCTTCTTCAGCACTAATAT
TTCTGGGATTTAAATAGTAATGTTTAAATTATGGTAAATGTAATTTAAAACATCTCAATTAAGTCTGTCTATCAATATTGTTCTTCAAGC
ATGTTTTAGACCTAGAAAAGTATGGTTTGGGGGAGGCTATTTTATTGTGTGGTTAGCACAAGGAATCTAATTTATAGCAAGTGTGAAATA
GTTACCATTTTTTCCTGATCTGTCATCTTCATAGCACAACAAAACGAAATGATGGAAATGCTCTTGAGCTCACAACATTTGTTTTTCTTT
TAAAGTAAATGCAAGTACCAAAGCTCACTACTGCGGTTTGCCTGTGCCTGGACAATGAGGCGGAGCCACTGTTGTTTTGTTGGGGCACCC
CCTTCCCTCCCCGGGTTTGCAAATAGAGGCTACCGGGTGCTGTATTCAGCAACACCTGTTTTACTATTTGTTATTAAACTATCATCTCCA
CCTTCCTTTTGATTAGCAATTTGTACTAAGAAACGAAACAATGTTATTTGGTGGTGTATAATTCTACTTTTCTAGTAGATTACTGTGTGG
AATTCTGTGAAAAATATTTGAGAAAAGGCCTGTATTGCATAAATAAATTCTTTGTATGTTGTGAACTTTGATCTCTATTTCTCTTGCAAC
AGACTTCAAGTGGTCCCTCTTTTTTTCCTACACACTCAGCTCTTCTCTAAAAGCAAGGATTTGGAATGAACAATTCAGTTTGACAGAAAA

>In-frame_ENST00000478576_ENST00000510413_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(amino acids)=1463AA_start in transcript=1990_stop in transcript=6381
MENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEIEAEKSMSSGGILRQCLRLVCAVAVRNCLECQQHSQLKTRGDKALKPMHSL
IPLGKSAAKSPVDIVTGGISPVRDLDRLLQDMDINRLRAVVFRDIEDSKQAQFLALAVVYFISVLMVSKYRDILEPQNERHSQSCTETGS
ENENVSLSEITPAAFSTLTTASVEESESTSSARRRDSGIGEETATGLGSHVEVTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDR
GNDLDTKATPSVSVSKNVNVKDILRSLVNIPADGVTVDPALLPPACLGALGDLSVEQPVQFRSFDRSVIVAAKKSAVSPSTFNTSIPTNA
VSVVSSVDSAQASDMGGESPGSRSSNAKLPSVPTVDSVSQDPVSNMSITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEG
TSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSQTMKDHLVRVANEAEFILSRQRAEDIHRHAEFESLCAQYSADK
REDEKMCDHLIRAAKYRDHVTATQLIQKIINILTDKHGAWGNSAVSRPLEFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEHATD
EDILAKGKQSIRSQALGNQNSENEILLEGDDDTLSSVDEKDLENLAGPVSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKID
PKILAYTEGLHGKWLFTEIRSIFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRISLASPRQLFKAS
NMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQVPKF
HYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVS
DVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPS
QLLIEPHPPRGSAMQVSPLMFTDKAQQDVIMVLKFPSNSPVTHVAANTQPGLATPAVITVTANRLFAVNKWHNLPAHQGAVQDQPYQLPV
EIDPLIASNTGMHRRQITDLLDQSIQVHSQCFVITSDNRYILVCGFWDKSFRVYSTDTGRLIQVVFGHWDVVTCLARSESYIGGNCYILS
GSRDATLLLWYWNGKCSGIGDNPGETAAPRAILTGHDYEVTCAAVCAELGLVLSGSQEGPCLIHSMNGDLLRTLEGPENCLKPKLIQASR
EGHCVIFYENGLFCTFSVNGKLQATMETDDNIRAIQLSRDGQYLLTGGDRGVVVVRQVSDLKQLFAYPGCDAGIRAMALSYDQRCIISGM

--------------------------------------------------------------
>In-frame_ENST00000264263_ENST00000535741_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(transcript)=7540nt_BP=1859nt
CGGCGCCACGGGACTTTGACGCGTGCTCTGCGCTTGCCATGAGACTCCTGGGAGCTGCAGCCGTCGCGGCTCTGGGGCGCGGAAGGGCCC
CCGCCTCCCTAGGCTGGCAGAGGAAGCAGGTTAATTGGAAGGCCTGCCGATGGTCTTCATCAGGGGTGATTCCTAATGAAAAAATACGAA
ATATTGGAATCTCAGCTCACATTGATTCTGGGAAAACTACATTAACAGAACGAGTCCTTTACTACACTGGCAGAATTGCAAAGATGCATG
AGGTGAAAGGTAAAGATGGAGTTGGTGCTGTCATGGATTCCATGGAACTAGAGAGACAAAGAGGAATCACTATTCAGTCAGCAGCCACTT
ACACCATGTGGAAAGATGTCAATATTAACATTATAGATACTCCTGGGCATGTGGACTTCACAATAGAAGTGGAAAGGGCCCTGAGAGTGT
TGGATGGTGCAGTCCTTGTTCTCTGTGCTGTTGGAGGGGTACAGTGCCAGACCATGACTGTCAATCGTCAGATGAAGCGCTACAACGTTC
CGTTTCTAACTTTTATTAACAAATTGGACCGAATGGGCTCCAACCCAGCCAGGGCCCTGCAGCAAATGAGGTCTAAACTAAATCATAATG
CAGCGTTTATGCAGATACCCATGGGTTTGGAGGGTAATTTTAAAGGTATTGTAGATCTTATTGAGGAACGAGCCATCTATTTTGATGGAG
ACTTTGGGCACTTCCTGAGGGATTTCCTTCCTCTGCTATGGAATTGGGATCGCAGGTCTGGCAGTCAGATTGTTCGATATGGTGAGATTC
CAGCTGAATTAAGGGCGGCGGCCACTGACCACCGGCAGGAGCTAATTGAATGTGTTGCCAATTCAGATGAACAGCTTGGTGAGATGTTTC
TGGAAGAAAAAATCCCCTCGATTTCTGATTTAAAGCTAGCAATTCGAAGAGCTACTCTGAAAAGATCATTTACTCCTGTATTTTTGGGAA
GCGCCTTGAAGAACAAAGGAGTTCAGCCTCTTTTAGATGCTGTTTTAGAATACCTCCCAAATCCATCTGAAGTCCAGAACTATGCTATTC
TCAATAAAGAGGATGACTCAAAAGAGAAAACCAAAATCCTAATGAACTCCAGTAGAGACAATTCCCACCCATTTGTAGGCCTGGCTTTTA
AACTGGAGGTAGGTCGATTTGGACAATTAACTTATGTTCGCAGTTATCAGGGAGAGCTAAAGAAGGGTGACACCATCTATAACACAAGGA
CAAGAAAGAAAGTACGGTTGCAACGGCTGGCTCGCATGCATGCCGACATGATGGAGGATGTTGAGGAAGTATATGCCGGAGACATCTGTG
CATTGTTTGGCATTGACTGTGCTAGTGGAGACACATTCACAGACAAAGCCAACAGCGGCCTTTCTATGGAGTCAATTCATGTTCCTGATC
CTGTCATTTCAATAGCAATGAAGCCTTCTAACAAGAACGATCTGGAAAAATTTTCAAAAGGTATTGGCAGGTTTACAAGAGAAGATCCCA
CATTTAAAGTATACTTTGACACTGAGAACAAAGAGACAGTTATATCTGGAATGGGAGAATTACACCTGGAAATCTATGCTCAGAGGCTGG
AAAGAGAGTATGGCTGTCCTTGTATCACAGGAAAGCCAAAAGTTGCCTTTCGAGAGACCATTACTGCCCCTGTCCCGTTTGACTTTACAC
ATAAAAAACAATCAGGTGGTGCAGGCCAGTATGGAAAAGTAATAGGTGTCCTGGAGCCTCTGGACCCAGAGGACTACACTAAATTGGAAT
TTTCAGATGAAACATTCGGATCAAATATTCCAAAGCAGTTTGTGCCTGCTGTAGAAAAGCATGAACTGGAAAATATTGAACCTACTCAAG
GCCTTTCAATAGAAGCCTCTGTGACATTTTTGCAGAGGCTAATTAGCCTTGTGGATGTGCTTATATTTGCAAGTTCTCTTGGCTTTACTG
AAATTGAAGCTGAAAAAAGTATGTCATCTGGAGGAATTTTGCGGCAGTGTCTCCGACTAGTTTGTGCAGTCGCAGTAAGGAATTGCTTGG
AGTGTCAACAGCATTCACAACTGAAAACTAGGGGAGATAAAGCCTTGAAACCAATGCATAGCCTTATTCCTTTAGGGAAATCTGCAGCGA
AGAGCCCAGTGGACATTGTGACTGGCGGTATATCTCCAGTAAGAGATCTTGACAGGCTTCTACAGGACATGGATATTAATCGGCTTAGGG
CAGTTGTTTTCAGAGACATAGAGGATAGCAAACAAGCTCAATTTTTAGCCTTGGCAGTAGTATACTTTATCTCTGTTCTTATGGTCTCCA
AGTACAGAGACATTTTGGAACCCCAAAATGAAAGGCATAGCCAGTCATGTACAGAAACTGGCAGTGAAAATGAGAATGTATCACTCTCTG
AAATCACACCAGCAGCATTCAGCACTTTAACTACGGCATCAGTGGAAGAATCTGAAAGCACATCATCTGCTCGAAGGAGGGACTCAGGCA
TTGGGGAAGAAACAGCCACTGGTTTAGGAAGCCATGTGGAAGTAACTCCTCACACAGCACCTCCTGGTGTCAGTGCAGGCCCAGATGCAA
TCAGCGAGGTGCTATCTACTCTTTCTTTAGAAGTCAATAAGTCTCCGGAAACCAAAAATGATAGAGGAAATGACTTGGACACTAAGGCTA
CACCGTCAGTTTCAGTTTCAAAAAACGTCAATGTGAAAGACATTCTCCGAAGCTTGGTTAACATACCAGCAGATGGAGTCACAGTGGATC
CTGCCCTTCTGCCACCAGCCTGCCTTGGAGCCCTTGGTGATCTATCTGTGGAACAACCCGTGCAGTTCAGATCTTTTGACAGAAGTGTCA
TTGTTGCAGCAAAAAAGTCAGCAGTCTCACCTTCCACCTTTAATACAAGCATACCTACCAATGCTGTCAGTGTGGTTTCCTCAGTAGATT
CAGCCCAAGCCTCAGATATGGGAGGAGAATCACCAGGCAGTAGATCATCTAATGCAAAATTGCCCTCAGTTCCAACAGTTGATTCAGTTT
CACAAGATCCGGTTTCAAATATGAGTATTACAGAGAGGCTTGAACACGCTTTGGAAAAGGCAGCTCCTCTCCTTCGTGAGATTTTTGTGG
ATTTTGCACCTTTTCTTTCTCGGACACTTTTGGGTAGCCATGGACAAGAACTGCTTATAGAAGGAACAAGTCTGGTTTGCATGAAGTCGA
GTAGTTCAGTTGTGGAATTGGTTATGCTACTGTGTTCTCAGGAGTGGCAAAATTCTATTCAGAAGAATGCAGGCCTTGCTTTTATCGAAC
TTGTCAATGAAGGAAGGTTGCTTAGCCAGACAATGAAGGATCATCTAGTAAGAGTAGCAAATGAAGCTGAATTTATCCTGAGCAGGCAGA
GAGCAGAAGATATTCACAGACATGCGGAATTTGAGTCACTGTGTGCCCAGTATTCTGCAGACAAACGAGAAGATGAGAAGATGTGTGATC
ATTTGATAAGAGCAGCAAAATATCGTGACCACGTGACAGCAACTCAACTAATCCAGAAAATTATCAACATTCTCACAGACAAGCATGGAG
CCTGGGGAAATTCTGCAGTGAGTCGTCCTCTTGAGTTCTGGCGCCTTGACTACTGGGAAGATGACTTGCGGCGCCGGCGACGATTTGTGC
GTAACCCTCTAGGATCGACACATCCTGAAGCGACACTAAAAACAGCCGTGGAACATGCCACAGATGAAGATATCCTTGCTAAAGGAAAAC
AGTCCATCAGGAGTCAGGCTTTAGGAAATCAGAACTCAGAAAACGAGATCCTCCTGGAAGGCGATGATGATACTCTGTCATCCGTGGATG
AGAAAGATTTAGAGAATCTTGCCGGTCCTGTTAGCCTGAGCACACCAGCTCAGCTTGTGGCCCCCTCTGTTGTAGTAAAGGGCACTCTTT
CTGTCACCTCCTCCGAACTCTATTTTGAGGTGGATGAAGAGGATCCTAACTTCAAAAAAATCGACCCCAAGATCTTGGCATATACAGAAG
GGCTGCATGGAAAATGGCTGTTCACAGAGATACGATCAATCTTTTCTCGTCGTTATCTTTTGCAAAATACAGCCCTGGAGATCTTTATGG
CAAACAGAGTTGCTGTGATGTTCAACTTCCCAGACCCTGCAACAGTAAAGAAAGTGGTTAACTATCTACCTCGTGTTGGCGTTGGAACAA
GTTTTGGATTGCCTCAAACCAGACGTATTTCATTAGCTAGTCCACGTCAGCTTTTTAAGGCTTCTAATATGACCCAGCGATGGCAACACA
GAGAGATATCTAATTTTGAGTACTTGATGTTTCTCAACACGATAGCAGGACGGAGTTATAATGACTTAAATCAGTATCCAGTGTTTCCTT
GGGTCATCACTAATTATGAATCAGAAGAACTGGATCTTACCTTGCCCACCAACTTCAGAGATTTGTCCAAGCCAATAGGAGCTCTGAACC
CAAAAAGAGCAGCATTCTTCGCTGAGCGTTATGAATCATGGGAAGATGATCAAGTTCCAAAGTTTCACTATGGTACTCATTACTCAACTG
CAAGTTTTGTTCTTGCATGGCTGCTAAGAATAGAACCCTTTACAACTTATTTCCTAAATTTGCAAGGAGGCAAATTTGATCATGCAGATC
GAACTTTTTCATCAATTTCCAGAGCTTGGCGAAACAGTCAGCGTGATACCTCTGATATTAAGGAGTTGATCCCTGAATTTTATTATCTCC
CTGAGATGTTTGTCAACTTCAATAATTATAATCTTGGAGTGATGGATGATGGGACAGTAGTGTCTGATGTCGAACTTCCTCCTTGGGCCA
AAACCTCAGAAGAATTTGTTCACATAAACAGATTGGCCCTGGAGAGTGAATTTGTTTCCTGCCAGCTTCACCAATGGATTGATCTCATTT
TTGGCTATAAACAGCAAGGACCAGAAGCTGTCCGAGCCCTCAATGTGTTCTATTACTTGACCTATGAAGGAGCTGTCAATCTGAATTCAA
TAACTGATCCTGTGTTGAGAGAGGCTGTTGAAGCTCAAATCCGAAGTTTTGGACAGACTCCTTCTCAACTACTCATAGAGCCCCATCCTC
CCAGAGGTTCTGCCATGCAAGTGAGTCCATTGATGTTCACAGACAAAGCCCAGCAGGATGTTATCATGGTCCTCAAGTTTCCCTCCAACT
CCCCTGTTACTCACGTGGCAGCCAACACCCAGCCTGGTTTGGCAACTCCCGCTGTGATCACAGTCACTGCTAACAGGTTATTTGCGGTGA
ACAAATGGCACAACCTTCCTGCTCATCAAGGTGCTGTACAAGACCAGCCATACCAGCTGCCAGTGGAAATCGATCCTCTCATAGCCAGCA
ATACAGGAATGCACAGGAGGCAAATCACTGACCTTTTAGACCAAAGTATTCAAGTGCATTCCCAGTGCTTTGTCATCACTTCAGACAACC
GCTATATTCTCGTCTGTGGCTTCTGGGATAAAAGTTTCAGAGTCTATTCTACAGACACAGGAAGATTGATCCAAGTGGTGTTTGGCCATT
GGGATGTCGTCACTTGCCTTGCTCGTTCTGAGTCATATATTGGGGGAAATTGCTACATTCTCTCAGGGTCACGTGATGCAACTCTTTTGC
TGTGGTATTGGAATGGAAAATGCAGTGGGATTGGAGATAACCCAGGCAGTGAGACTGCTGCTCCTCGGGCCATTTTGACCGGCCATGACT
ATGAGGTCACATGTGCTGCGGTGTGTGCGGAGCTAGGCCTGGTGTTGAGTGGTTCACAAGAAGGACCATGTCTCATACATTCCATGAATG
GAGACTTGTTGAGGACCTTGGAGGGTCCTGAAAACTGCCTGAAACCAAAACTCATTCAGGCTTCAAGAGAGGGTCATTGTGTCATATTCT
ATGAAAACGGCCTCTTCTGTACATTCAGTGTGAATGGAAAACTCCAGGCCACGATGGAAACAGATGATAACATAAGAGCCATCCAGCTGA
GCCGAGATGGGCAGTACCTGCTCACAGGAGGAGACAGAGGAGTGGTCGTGGTCCGGCAGGTGTCGGACCTCAAGCAGCTCTTTGCCTATC
CAGGATGTGACGCTGGAATCCGGGCCATGGCGCTGTCTTACGACCAGAGGTGCATCATTTCTGGCATGGCTTCAGGAAGCATTGTGCTAT
TTTACAACGACTTTAACCGGTGGCATCATGAATACCAAACCCGCTACTGATGGTGACAGCTGTACATCAACTCTGCCCCTAGGATGAGCA
GAAGTACCTGGAGCATCATTCTCTTCTACCACATCTGAATGTAACTTAAATTTGCTCAAAGAAGCAAAATATTTTTTAAAGTTATTAATA
ATTGCTATTTTTGTAGTCTTTGCTTGACTTTTTTGGGGGGGATTAGCAAAGCAGAAAACTGGCTGCTGGGTTCTGTAGTTTTAAAAAATC
TATATTTTTAGTCATAATGAGAAGTCTATTTTCACCAATTATGGAAACATACAGTGGAGCAAGTAAACCACTTATTCCAGCTATAATATT
ATGAAGAACATTTCCCATGCATCTACAAGCTTGAGAAATAGGATTTTCACAGTGGGGAAGTGGGTTACAATATTGGAATAGGAAAATTTG
ATGCTGTAATTTGGGTCCTGTATTTTTCCAAACAACTGTGCTTCTTCAGCACTAATATTTCTGGGATTTAAATAGTAATGTTTAAATTAT
GGTAAATGTAATTTAAAACATCTCAATTAAGTCTGTCTATCAATATTGTTCTTCAAGCATGTTTTAGACCTAGAAAAGTATGGTTTGGGG
GAGGCTATTTTATTGTGTGGTTAGCACAAGGAATCTAATTTATAGCAAGTGTGAAATAGTTACCATTTTTTCCTGATCTGTCATCTTCAT
AGCACAACAAAACGAAATGATGGAAATGCTCTTGAGCTCACAACATTTGTTTTTCTTTTAAAGTAAATGCAAGTACCAAAGCTCACTACT
GCGGTTTGCCTGTGCCTGGACAATGAGGCGGAGCCACTGTTGTTTTGTTGGGGCACCCCCTTCCCTCCCCGGGTTTGCAAATAGAGGCTA
CCGGGTGCTGTATTCAGCAACACCTGTTTTACTATTTGTTATTAAACTATCATCTCCACCTTCCTTTTGATTAGCAATTTGTACTAAGAA
ACGAAACAATGTTATTTGGTGGTGTATAATTCTACTTTTCTAGTAGATTACTGTGTGGAATTCTGTGAAAAATATTTGAGAAAAGGCCTG
TATTGCATAAATAAATTCTTTGTATGTTGTGAACTTTGATCTCTATTTCTCTTGCAACAGACTTCAAGTGGTCCCTCTTTTTTTCCTACA
CACTCAGCTCTTCTCTAAAAGCAAGGATTTGGAATGAACAATTCAGTTTGACAGAAAAAGCTGAATAAAATGGCATCTGTAATTGAATTG

>In-frame_ENST00000264263_ENST00000535741_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(amino acids)=2073AA_start in transcript=38_stop in transcript=6259
MRLLGAAAVAALGRGRAPASLGWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMD
SMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMG
SNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGHFLRDFLPLLWNWDRRSGSQIVRYGEIPAELRAAATDHRQ
ELIECVANSDEQLGEMFLEEKIPSISDLKLAIRRATLKRSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKI
LMNSSRDNSHPFVGLAFKLEVGRFGQLTYVRSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTF
TDKANSGLSMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHLEIYAQRLEREYGCPCITGKP
KVAFRETITAPVPFDFTHKKQSGGAGQYGKVIGVLEPLDPEDYTKLEFSDETFGSNIPKQFVPAVEKHELENIEPTQGLSIEASVTFLQR
LISLVDVLIFASSLGFTEIEAEKSMSSGGILRQCLRLVCAVAVRNCLECQQHSQLKTRGDKALKPMHSLIPLGKSAAKSPVDIVTGGISP
VRDLDRLLQDMDINRLRAVVFRDIEDSKQAQFLALAVVYFISVLMVSKYRDILEPQNERHSQSCTETGSENENVSLSEITPAAFSTLTTA
SVEESESTSSARRRDSGIGEETATGLGSHVEVTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDRGNDLDTKATPSVSVSKNVNVK
DILRSLVNIPADGVTVDPALLPPACLGALGDLSVEQPVQFRSFDRSVIVAAKKSAVSPSTFNTSIPTNAVSVVSSVDSAQASDMGGESPG
SRSSNAKLPSVPTVDSVSQDPVSNMSITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCS
QEWQNSIQKNAGLAFIELVNEGRLLSQTMKDHLVRVANEAEFILSRQRAEDIHRHAEFESLCAQYSADKREDEKMCDHLIRAAKYRDHVT
ATQLIQKIINILTDKHGAWGNSAVSRPLEFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEHATDEDILAKGKQSIRSQALGNQNS
ENEILLEGDDDTLSSVDEKDLENLAGPVSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTEIRS
IFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRISLASPRQLFKASNMTQRWQHREISNFEYLMFLN
TIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLRIEP
FTTYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAKTSEEFVHINRLA
LESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQVSPLMF
TDKAQQDVIMVLKFPSNSPVTHVAANTQPGLATPAVITVTANRLFAVNKWHNLPAHQGAVQDQPYQLPVEIDPLIASNTGMHRRQITDLL
DQSIQVHSQCFVITSDNRYILVCGFWDKSFRVYSTDTGRLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWYWNGKCSGIGD
NPGSETAAPRAILTGHDYEVTCAAVCAELGLVLSGSQEGPCLIHSMNGDLLRTLEGPENCLKPKLIQASREGHCVIFYENGLFCTFSVNG
KLQATMETDDNIRAIQLSRDGQYLLTGGDRGVVVVRQVSDLKQLFAYPGCDAGIRAMALSYDQRCIISGMASGSIVLFYNDFNRWHHEYQ

--------------------------------------------------------------
>In-frame_ENST00000264263_ENST00000510413_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(transcript)=7448nt_BP=1859nt
CGGCGCCACGGGACTTTGACGCGTGCTCTGCGCTTGCCATGAGACTCCTGGGAGCTGCAGCCGTCGCGGCTCTGGGGCGCGGAAGGGCCC
CCGCCTCCCTAGGCTGGCAGAGGAAGCAGGTTAATTGGAAGGCCTGCCGATGGTCTTCATCAGGGGTGATTCCTAATGAAAAAATACGAA
ATATTGGAATCTCAGCTCACATTGATTCTGGGAAAACTACATTAACAGAACGAGTCCTTTACTACACTGGCAGAATTGCAAAGATGCATG
AGGTGAAAGGTAAAGATGGAGTTGGTGCTGTCATGGATTCCATGGAACTAGAGAGACAAAGAGGAATCACTATTCAGTCAGCAGCCACTT
ACACCATGTGGAAAGATGTCAATATTAACATTATAGATACTCCTGGGCATGTGGACTTCACAATAGAAGTGGAAAGGGCCCTGAGAGTGT
TGGATGGTGCAGTCCTTGTTCTCTGTGCTGTTGGAGGGGTACAGTGCCAGACCATGACTGTCAATCGTCAGATGAAGCGCTACAACGTTC
CGTTTCTAACTTTTATTAACAAATTGGACCGAATGGGCTCCAACCCAGCCAGGGCCCTGCAGCAAATGAGGTCTAAACTAAATCATAATG
CAGCGTTTATGCAGATACCCATGGGTTTGGAGGGTAATTTTAAAGGTATTGTAGATCTTATTGAGGAACGAGCCATCTATTTTGATGGAG
ACTTTGGGCACTTCCTGAGGGATTTCCTTCCTCTGCTATGGAATTGGGATCGCAGGTCTGGCAGTCAGATTGTTCGATATGGTGAGATTC
CAGCTGAATTAAGGGCGGCGGCCACTGACCACCGGCAGGAGCTAATTGAATGTGTTGCCAATTCAGATGAACAGCTTGGTGAGATGTTTC
TGGAAGAAAAAATCCCCTCGATTTCTGATTTAAAGCTAGCAATTCGAAGAGCTACTCTGAAAAGATCATTTACTCCTGTATTTTTGGGAA
GCGCCTTGAAGAACAAAGGAGTTCAGCCTCTTTTAGATGCTGTTTTAGAATACCTCCCAAATCCATCTGAAGTCCAGAACTATGCTATTC
TCAATAAAGAGGATGACTCAAAAGAGAAAACCAAAATCCTAATGAACTCCAGTAGAGACAATTCCCACCCATTTGTAGGCCTGGCTTTTA
AACTGGAGGTAGGTCGATTTGGACAATTAACTTATGTTCGCAGTTATCAGGGAGAGCTAAAGAAGGGTGACACCATCTATAACACAAGGA
CAAGAAAGAAAGTACGGTTGCAACGGCTGGCTCGCATGCATGCCGACATGATGGAGGATGTTGAGGAAGTATATGCCGGAGACATCTGTG
CATTGTTTGGCATTGACTGTGCTAGTGGAGACACATTCACAGACAAAGCCAACAGCGGCCTTTCTATGGAGTCAATTCATGTTCCTGATC
CTGTCATTTCAATAGCAATGAAGCCTTCTAACAAGAACGATCTGGAAAAATTTTCAAAAGGTATTGGCAGGTTTACAAGAGAAGATCCCA
CATTTAAAGTATACTTTGACACTGAGAACAAAGAGACAGTTATATCTGGAATGGGAGAATTACACCTGGAAATCTATGCTCAGAGGCTGG
AAAGAGAGTATGGCTGTCCTTGTATCACAGGAAAGCCAAAAGTTGCCTTTCGAGAGACCATTACTGCCCCTGTCCCGTTTGACTTTACAC
ATAAAAAACAATCAGGTGGTGCAGGCCAGTATGGAAAAGTAATAGGTGTCCTGGAGCCTCTGGACCCAGAGGACTACACTAAATTGGAAT
TTTCAGATGAAACATTCGGATCAAATATTCCAAAGCAGTTTGTGCCTGCTGTAGAAAAGCATGAACTGGAAAATATTGAACCTACTCAAG
GCCTTTCAATAGAAGCCTCTGTGACATTTTTGCAGAGGCTAATTAGCCTTGTGGATGTGCTTATATTTGCAAGTTCTCTTGGCTTTACTG
AAATTGAAGCTGAAAAAAGTATGTCATCTGGAGGAATTTTGCGGCAGTGTCTCCGACTAGTTTGTGCAGTCGCAGTAAGGAATTGCTTGG
AGTGTCAACAGCATTCACAACTGAAAACTAGGGGAGATAAAGCCTTGAAACCAATGCATAGCCTTATTCCTTTAGGGAAATCTGCAGCGA
AGAGCCCAGTGGACATTGTGACTGGCGGTATATCTCCAGTAAGAGATCTTGACAGGCTTCTACAGGACATGGATATTAATCGGCTTAGGG
CAGTTGTTTTCAGAGACATAGAGGATAGCAAACAAGCTCAATTTTTAGCCTTGGCAGTAGTATACTTTATCTCTGTTCTTATGGTCTCCA
AGTACAGAGACATTTTGGAACCCCAAAATGAAAGGCATAGCCAGTCATGTACAGAAACTGGCAGTGAAAATGAGAATGTATCACTCTCTG
AAATCACACCAGCAGCATTCAGCACTTTAACTACGGCATCAGTGGAAGAATCTGAAAGCACATCATCTGCTCGAAGGAGGGACTCAGGCA
TTGGGGAAGAAACAGCCACTGGTTTAGGAAGCCATGTGGAAGTAACTCCTCACACAGCACCTCCTGGTGTCAGTGCAGGCCCAGATGCAA
TCAGCGAGGTGCTATCTACTCTTTCTTTAGAAGTCAATAAGTCTCCGGAAACCAAAAATGATAGAGGAAATGACTTGGACACTAAGGCTA
CACCGTCAGTTTCAGTTTCAAAAAACGTCAATGTGAAAGACATTCTCCGAAGCTTGGTTAACATACCAGCAGATGGAGTCACAGTGGATC
CTGCCCTTCTGCCACCAGCCTGCCTTGGAGCCCTTGGTGATCTATCTGTGGAACAACCCGTGCAGTTCAGATCTTTTGACAGAAGTGTCA
TTGTTGCAGCAAAAAAGTCAGCAGTCTCACCTTCCACCTTTAATACAAGCATACCTACCAATGCTGTCAGTGTGGTTTCCTCAGTAGATT
CAGCCCAAGCCTCAGATATGGGAGGAGAATCACCAGGCAGTAGATCATCTAATGCAAAATTGCCCTCAGTTCCAACAGTTGATTCAGTTT
CACAAGATCCGGTTTCAAATATGAGTATTACAGAGAGGCTTGAACACGCTTTGGAAAAGGCAGCTCCTCTCCTTCGTGAGATTTTTGTGG
ATTTTGCACCTTTTCTTTCTCGGACACTTTTGGGTAGCCATGGACAAGAACTGCTTATAGAAGGAACAAGTCTGGTTTGCATGAAGTCGA
GTAGTTCAGTTGTGGAATTGGTTATGCTACTGTGTTCTCAGGAGTGGCAAAATTCTATTCAGAAGAATGCAGGCCTTGCTTTTATCGAAC
TTGTCAATGAAGGAAGGTTGCTTAGCCAGACAATGAAGGATCATCTAGTAAGAGTAGCAAATGAAGCTGAATTTATCCTGAGCAGGCAGA
GAGCAGAAGATATTCACAGACATGCGGAATTTGAGTCACTGTGTGCCCAGTATTCTGCAGACAAACGAGAAGATGAGAAGATGTGTGATC
ATTTGATAAGAGCAGCAAAATATCGTGACCACGTGACAGCAACTCAACTAATCCAGAAAATTATCAACATTCTCACAGACAAGCATGGAG
CCTGGGGAAATTCTGCAGTGAGTCGTCCTCTTGAGTTCTGGCGCCTTGACTACTGGGAAGATGACTTGCGGCGCCGGCGACGATTTGTGC
GTAACCCTCTAGGATCGACACATCCTGAAGCGACACTAAAAACAGCCGTGGAACATGCCACAGATGAAGATATCCTTGCTAAAGGAAAAC
AGTCCATCAGGAGTCAGGCTTTAGGAAATCAGAACTCAGAAAACGAGATCCTCCTGGAAGGCGATGATGATACTCTGTCATCCGTGGATG
AGAAAGATTTAGAGAATCTTGCCGGTCCTGTTAGCCTGAGCACACCAGCTCAGCTTGTGGCCCCCTCTGTTGTAGTAAAGGGCACTCTTT
CTGTCACCTCCTCCGAACTCTATTTTGAGGTGGATGAAGAGGATCCTAACTTCAAAAAAATCGACCCCAAGATCTTGGCATATACAGAAG
GGCTGCATGGAAAATGGCTGTTCACAGAGATACGATCAATCTTTTCTCGTCGTTATCTTTTGCAAAATACAGCCCTGGAGATCTTTATGG
CAAACAGAGTTGCTGTGATGTTCAACTTCCCAGACCCTGCAACAGTAAAGAAAGTGGTTAACTATCTACCTCGTGTTGGCGTTGGAACAA
GTTTTGGATTGCCTCAAACCAGACGTATTTCATTAGCTAGTCCACGTCAGCTTTTTAAGGCTTCTAATATGACCCAGCGATGGCAACACA
GAGAGATATCTAATTTTGAGTACTTGATGTTTCTCAACACGATAGCAGGACGGAGTTATAATGACTTAAATCAGTATCCAGTGTTTCCTT
GGGTCATCACTAATTATGAATCAGAAGAACTGGATCTTACCTTGCCCACCAACTTCAGAGATTTGTCCAAGCCAATAGGAGCTCTGAACC
CAAAAAGAGCAGCATTCTTCGCTGAGCGTTATGAATCATGGGAAGATGATCAAGTTCCAAAGTTTCACTATGGTACTCATTACTCAACTG
CAAGTTTTGTTCTTGCATGGCTGCTAAGAATAGAACCCTTTACAACTTATTTCCTAAATTTGCAAGGAGGCAAATTTGATCATGCAGATC
GAACTTTTTCATCAATTTCCAGAGCTTGGCGAAACAGTCAGCGTGATACCTCTGATATTAAGGAGTTGATCCCTGAATTTTATTATCTCC
CTGAGATGTTTGTCAACTTCAATAATTATAATCTTGGAGTGATGGATGATGGGACAGTAGTGTCTGATGTCGAACTTCCTCCTTGGGCCA
AAACCTCAGAAGAATTTGTTCACATAAACAGATTGGCCCTGGAGAGTGAATTTGTTTCCTGCCAGCTTCACCAATGGATTGATCTCATTT
TTGGCTATAAACAGCAAGGACCAGAAGCTGTCCGAGCCCTCAATGTGTTCTATTACTTGACCTATGAAGGAGCTGTCAATCTGAATTCAA
TAACTGATCCTGTGTTGAGAGAGGCTGTTGAAGCTCAAATCCGAAGTTTTGGACAGACTCCTTCTCAACTACTCATAGAGCCCCATCCTC
CCAGAGGTTCTGCCATGCAAGTGAGTCCATTGATGTTCACAGACAAAGCCCAGCAGGATGTTATCATGGTCCTCAAGTTTCCCTCCAACT
CCCCTGTTACTCACGTGGCAGCCAACACCCAGCCTGGTTTGGCAACTCCCGCTGTGATCACAGTCACTGCTAACAGGTTATTTGCGGTGA
ACAAATGGCACAACCTTCCTGCTCATCAAGGTGCTGTACAAGACCAGCCATACCAGCTGCCAGTGGAAATCGATCCTCTCATAGCCAGCA
ATACAGGAATGCACAGGAGGCAAATCACTGACCTTTTAGACCAAAGTATTCAAGTGCATTCCCAGTGCTTTGTCATCACTTCAGACAACC
GCTATATTCTCGTCTGTGGCTTCTGGGATAAAAGTTTCAGAGTCTATTCTACAGACACAGGAAGATTGATCCAAGTGGTGTTTGGCCATT
GGGATGTCGTCACTTGCCTTGCTCGTTCTGAGTCATATATTGGGGGAAATTGCTACATTCTCTCAGGGTCACGTGATGCAACTCTTTTGC
TGTGGTATTGGAATGGAAAATGCAGTGGGATTGGAGATAACCCAGGTGAGACTGCTGCTCCTCGGGCCATTTTGACCGGCCATGACTATG
AGGTCACATGTGCTGCGGTGTGTGCGGAGCTAGGCCTGGTGTTGAGTGGTTCACAAGAAGGACCATGTCTCATACATTCCATGAATGGAG
ACTTGTTGAGGACCTTGGAGGGTCCTGAAAACTGCCTGAAACCAAAACTCATTCAGGCTTCAAGAGAGGGTCATTGTGTCATATTCTATG
AAAACGGCCTCTTCTGTACATTCAGTGTGAATGGAAAACTCCAGGCCACGATGGAAACAGATGATAACATAAGAGCCATCCAGCTGAGCC
GAGATGGGCAGTACCTGCTCACAGGAGGAGACAGAGGAGTGGTCGTGGTCCGGCAGGTGTCGGACCTCAAGCAGCTCTTTGCCTATCCAG
GATGTGACGCTGGAATCCGGGCCATGGCGCTGTCTTACGACCAGAGGTGCATCATTTCTGGCATGGCTTCAGGAAGCATTGTGCTATTTT
ACAACGACTTTAACCGGTGGCATCATGAATACCAAACCCGCTACTGATGGTGACAGCTGTACATCAACTCTGCCCCTAGGATGAGCAGAA
GTACCTGGAGCATCATTCTCTTCTACCACATCTGAATGTAACTTAAATTTGCTCAAAGAAGCAAAATATTTTTTAAAGTTATTAATAATT
GCTATTTTTGTAGTCTTTGCTTGACTTTTTTGGGGGGGATTAGCAAAGCAGAAAACTGGCTGCTGGGTTCTGTAGTTTTAAAAAATCTAT
ATTTTTAGTCATAATGAGAAGTCTATTTTCACCAATTATGGAAACATACAGTGGAGCAAGTAAACCACTTATTCCAGCTATAATATTATG
AAGAACATTTCCCATGCATCTACAAGCTTGAGAAATAGGATTTTCACAGTGGGGAAGTGGGTTACAATATTGGAATAGGAAAATTTGATG
CTGTAATTTGGGTCCTGTATTTTTCCAAACAACTGTGCTTCTTCAGCACTAATATTTCTGGGATTTAAATAGTAATGTTTAAATTATGGT
AAATGTAATTTAAAACATCTCAATTAAGTCTGTCTATCAATATTGTTCTTCAAGCATGTTTTAGACCTAGAAAAGTATGGTTTGGGGGAG
GCTATTTTATTGTGTGGTTAGCACAAGGAATCTAATTTATAGCAAGTGTGAAATAGTTACCATTTTTTCCTGATCTGTCATCTTCATAGC
ACAACAAAACGAAATGATGGAAATGCTCTTGAGCTCACAACATTTGTTTTTCTTTTAAAGTAAATGCAAGTACCAAAGCTCACTACTGCG
GTTTGCCTGTGCCTGGACAATGAGGCGGAGCCACTGTTGTTTTGTTGGGGCACCCCCTTCCCTCCCCGGGTTTGCAAATAGAGGCTACCG
GGTGCTGTATTCAGCAACACCTGTTTTACTATTTGTTATTAAACTATCATCTCCACCTTCCTTTTGATTAGCAATTTGTACTAAGAAACG
AAACAATGTTATTTGGTGGTGTATAATTCTACTTTTCTAGTAGATTACTGTGTGGAATTCTGTGAAAAATATTTGAGAAAAGGCCTGTAT
TGCATAAATAAATTCTTTGTATGTTGTGAACTTTGATCTCTATTTCTCTTGCAACAGACTTCAAGTGGTCCCTCTTTTTTTCCTACACAC

>In-frame_ENST00000264263_ENST00000510413_TCGA-BP-4352-01A_GFM1_chr3_158399946_+_LRBA_chr4_151770150_length(amino acids)=2072AA_start in transcript=38_stop in transcript=6256
MRLLGAAAVAALGRGRAPASLGWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMD
SMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMG
SNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGHFLRDFLPLLWNWDRRSGSQIVRYGEIPAELRAAATDHRQ
ELIECVANSDEQLGEMFLEEKIPSISDLKLAIRRATLKRSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKI
LMNSSRDNSHPFVGLAFKLEVGRFGQLTYVRSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTF
TDKANSGLSMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHLEIYAQRLEREYGCPCITGKP
KVAFRETITAPVPFDFTHKKQSGGAGQYGKVIGVLEPLDPEDYTKLEFSDETFGSNIPKQFVPAVEKHELENIEPTQGLSIEASVTFLQR
LISLVDVLIFASSLGFTEIEAEKSMSSGGILRQCLRLVCAVAVRNCLECQQHSQLKTRGDKALKPMHSLIPLGKSAAKSPVDIVTGGISP
VRDLDRLLQDMDINRLRAVVFRDIEDSKQAQFLALAVVYFISVLMVSKYRDILEPQNERHSQSCTETGSENENVSLSEITPAAFSTLTTA
SVEESESTSSARRRDSGIGEETATGLGSHVEVTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDRGNDLDTKATPSVSVSKNVNVK
DILRSLVNIPADGVTVDPALLPPACLGALGDLSVEQPVQFRSFDRSVIVAAKKSAVSPSTFNTSIPTNAVSVVSSVDSAQASDMGGESPG
SRSSNAKLPSVPTVDSVSQDPVSNMSITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCS
QEWQNSIQKNAGLAFIELVNEGRLLSQTMKDHLVRVANEAEFILSRQRAEDIHRHAEFESLCAQYSADKREDEKMCDHLIRAAKYRDHVT
ATQLIQKIINILTDKHGAWGNSAVSRPLEFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEHATDEDILAKGKQSIRSQALGNQNS
ENEILLEGDDDTLSSVDEKDLENLAGPVSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTEIRS
IFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRISLASPRQLFKASNMTQRWQHREISNFEYLMFLN
TIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLRIEP
FTTYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAKTSEEFVHINRLA
LESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQVSPLMF
TDKAQQDVIMVLKFPSNSPVTHVAANTQPGLATPAVITVTANRLFAVNKWHNLPAHQGAVQDQPYQLPVEIDPLIASNTGMHRRQITDLL
DQSIQVHSQCFVITSDNRYILVCGFWDKSFRVYSTDTGRLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWYWNGKCSGIGD
NPGETAAPRAILTGHDYEVTCAAVCAELGLVLSGSQEGPCLIHSMNGDLLRTLEGPENCLKPKLIQASREGHCVIFYENGLFCTFSVNGK
LQATMETDDNIRAIQLSRDGQYLLTGGDRGVVVVRQVSDLKQLFAYPGCDAGIRAMALSYDQRCIISGMASGSIVLFYNDFNRWHHEYQT

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Fusion Gene PPI Analysis for GFM1-LRBA


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GFM1-LRBA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GFM1-LRBA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneGFM1C1836797Combined Oxidative Phosphorylation Deficiency 17CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneGFM1C0023264Leigh Disease6CLINGEN
HgeneGFM1C1838951LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY6CLINGEN
HgeneGFM1C1850597Leigh Syndrome Due To Mitochondrial Complex II Deficiency6CLINGEN
HgeneGFM1C1850598Leigh Syndrome due to Mitochondrial Complex III Deficiency6CLINGEN
HgeneGFM1C1850599Leigh Syndrome due to Mitochondrial Complex IV Deficiency6CLINGEN
HgeneGFM1C1850600Leigh Syndrome due to Mitochondrial Complex V Deficiency6CLINGEN
HgeneGFM1C2931891Necrotizing encephalopathy, infantile subacute, of Leigh6CLINGEN
TgeneLRBAC3553512IMMUNODEFICIENCY, COMMON VARIABLE, 8, WITH AUTOIMMUNITY7CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT