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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABCA9-CEP112 (FusionGDB2 ID:335)

Fusion Gene Summary for ABCA9-CEP112

check button Fusion gene summary
Fusion gene informationFusion gene name: ABCA9-CEP112
Fusion gene ID: 335
HgeneTgene
Gene symbol

ABCA9

CEP112

Gene ID

10350

201134

Gene nameATP binding cassette subfamily A member 9centrosomal protein 112
SynonymsEST640918CCDC46|MACOCO
Cytomap

17q24.2

17q24.1

Type of geneprotein-codingprotein-coding
DescriptionATP-binding cassette sub-family A member 9ATP-binding cassette A9ATP-binding cassette, sub-family A (ABC1), member 9centrosomal protein of 112 kDacentrosomal protein 112kDacoiled-coil domain-containing protein 46
Modification date2020031320200313
UniProtAcc.

Q8N8E3

Ensembl transtripts involved in fusion geneENST00000340001, ENST00000453985, 
ENST00000370732, ENST00000482072, 
ENST00000495634, 		ENST00000535342, 
ENST00000392769, ENST00000541355, 
ENST00000537949, ENST00000317442, 
ENST00000580482, 
Fusion gene scores* DoF score2 X 2 X 1=422 X 17 X 10=3740
# samples 221
** MAII scorelog2(2/4*10)=2.32192809488736log2(21/3740*10)=-4.15457703710888
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABCA9 [Title/Abstract] AND CEP112 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABCA9(67020355)-CEP112(63685336), # samples:3
Anticipated loss of major functional domain due to fusion event.ABCA9-CEP112 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ABCA9 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across CEP112 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A3M1-01AABCA9chr17

67020355

-CEP112chr17

63685336

-
ChimerDB4SARCTCGA-DX-A3M1-01AABCA9chr17

67020355

-CEP112chr17

63685336

-
ChimerDB4SARCTCGA-DX-A3M1-01AABCA9chr17

67020355

-CEP112chr17

63685336

-


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Fusion Gene ORF analysis for ABCA9-CEP112

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000340001ENST00000535342ABCA9chr17

67020355

-CEP112chr17

63685336

-
Frame-shiftENST00000340001ENST00000392769ABCA9chr17

67020355

-CEP112chr17

63685336

-
Frame-shiftENST00000340001ENST00000541355ABCA9chr17

67020355

-CEP112chr17

63685336

-
Frame-shiftENST00000340001ENST00000537949ABCA9chr17

67020355

-CEP112chr17

63685336

-
Frame-shiftENST00000340001ENST00000317442ABCA9chr17

67020355

-CEP112chr17

63685336

-
5CDS-5UTRENST00000340001ENST00000580482ABCA9chr17

67020355

-CEP112chr17

63685336

-
Frame-shiftENST00000453985ENST00000535342ABCA9chr17

67020355

-CEP112chr17

63685336

-
Frame-shiftENST00000453985ENST00000392769ABCA9chr17

67020355

-CEP112chr17

63685336

-
Frame-shiftENST00000453985ENST00000541355ABCA9chr17

67020355

-CEP112chr17

63685336

-
Frame-shiftENST00000453985ENST00000537949ABCA9chr17

67020355

-CEP112chr17

63685336

-
Frame-shiftENST00000453985ENST00000317442ABCA9chr17

67020355

-CEP112chr17

63685336

-
5CDS-5UTRENST00000453985ENST00000580482ABCA9chr17

67020355

-CEP112chr17

63685336

-
In-frameENST00000370732ENST00000535342ABCA9chr17

67020355

-CEP112chr17

63685336

-
In-frameENST00000370732ENST00000392769ABCA9chr17

67020355

-CEP112chr17

63685336

-
In-frameENST00000370732ENST00000541355ABCA9chr17

67020355

-CEP112chr17

63685336

-
In-frameENST00000370732ENST00000537949ABCA9chr17

67020355

-CEP112chr17

63685336

-
In-frameENST00000370732ENST00000317442ABCA9chr17

67020355

-CEP112chr17

63685336

-
5CDS-5UTRENST00000370732ENST00000580482ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-3CDSENST00000482072ENST00000535342ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-3CDSENST00000482072ENST00000392769ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-3CDSENST00000482072ENST00000541355ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-3CDSENST00000482072ENST00000537949ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-3CDSENST00000482072ENST00000317442ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-5UTRENST00000482072ENST00000580482ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-3CDSENST00000495634ENST00000535342ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-3CDSENST00000495634ENST00000392769ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-3CDSENST00000495634ENST00000541355ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-3CDSENST00000495634ENST00000537949ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-3CDSENST00000495634ENST00000317442ABCA9chr17

67020355

-CEP112chr17

63685336

-
intron-5UTRENST00000495634ENST00000580482ABCA9chr17

67020355

-CEP112chr17

63685336

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000370732ABCA9chr1767020355-ENST00000535342CEP112chr1763685336-311824241432437764
ENST00000370732ABCA9chr1767020355-ENST00000392769CEP112chr1763685336-311524241432437764
ENST00000370732ABCA9chr1767020355-ENST00000541355CEP112chr1763685336-283524241432437764
ENST00000370732ABCA9chr1767020355-ENST00000537949CEP112chr1763685336-274324241432437764
ENST00000370732ABCA9chr1767020355-ENST00000317442CEP112chr1763685336-284024241432437764

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000370732ENST00000535342ABCA9chr1767020355-CEP112chr1763685336-0.0003874930.9996125
ENST00000370732ENST00000392769ABCA9chr1767020355-CEP112chr1763685336-0.000395270.99960476
ENST00000370732ENST00000541355ABCA9chr1767020355-CEP112chr1763685336-0.0005087520.9994912
ENST00000370732ENST00000537949ABCA9chr1767020355-CEP112chr1763685336-0.0005198110.9994802
ENST00000370732ENST00000317442ABCA9chr1767020355-CEP112chr1763685336-0.0005135030.99948645

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Fusion Genomic Features for ABCA9-CEP112


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ABCA9-CEP112


check button Go to

FGviewer for the breakpoints of chr17:67020355-chr17:63685336

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CEP112

Q8N8E3

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-1739481_716760.33333333333341625.0DomainABC transporter 1
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-1738481_716760.33333333333341790.0DomainABC transporter 1
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-1739517_524760.33333333333341625.0Nucleotide bindingATP 1
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-1738517_524760.33333333333341790.0Nucleotide bindingATP 1
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-1739221_243760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-1739269_289760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-1739300_320760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-173931_51760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-1739329_349760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-1739354_374760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-1739398_418760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-1738221_243760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-1738269_289760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-1738300_320760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-173831_51760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-1738329_349760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-1738354_374760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-1738398_418760.33333333333341790.0TransmembraneHelical
TgeneCEP112chr17:67020355chr17:63685336ENST0000031744227277_954125.0212.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-17391288_1521760.33333333333341625.0DomainABC transporter 2
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-17381288_1521760.33333333333341790.0DomainABC transporter 2
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-161288_15210268.0DomainABC transporter 2
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-16481_7160268.0DomainABC transporter 1
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-17391326_1333760.33333333333341625.0Nucleotide bindingATP 2
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-17381326_1333760.33333333333341790.0Nucleotide bindingATP 2
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-161326_13330268.0Nucleotide bindingATP 2
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-16517_5240268.0Nucleotide bindingATP 1
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-17391026_1046760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-17391065_1085760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-17391108_1128760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-17391136_1156760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-17391163_1183760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-17391200_1220760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000340001-1739864_884760.33333333333341625.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-17381026_1046760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-17381065_1085760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-17381108_1128760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-17381136_1156760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-17381163_1183760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-17381200_1220760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000370732-1738864_884760.33333333333341790.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-161026_10460268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-161065_10850268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-161108_11280268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-161136_11560268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-161163_11830268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-161200_12200268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-16221_2430268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-16269_2890268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-16300_3200268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-1631_510268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-16329_3490268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-16354_3740268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-16398_4180268.0TransmembraneHelical
HgeneABCA9chr17:67020355chr17:63685336ENST00000495634-16864_8840268.0TransmembraneHelical
TgeneCEP112chr17:67020355chr17:63685336ENST000003927692227277_954869.0956.0Coiled coilOntology_term=ECO:0000255
TgeneCEP112chr17:67020355chr17:63685336ENST000005353422227277_954869.0956.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for ABCA9-CEP112


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000370732_ENST00000535342_TCGA-DX-A3M1-01A_ABCA9_chr17_67020355_-_CEP112_chr17_63685336_length(transcript)=3118nt_BP=2424nt
ATTCACAATGAATGTGAAATTAAAAGCATGATGTAGTAGTGACCCAAAAGGAATGTGAATTCTCCTCCAGAACATGCAGAGACCCATGGA
TGAACTGTGTTTCTAGATTTTTCCTCCAGCTTTCCTGAGAGAAACAGGTCAAAATGAGCAAGAGACGCATGAGCGTGGGTCAGCAAACAT
GGGCTCTTCTCTGCAAGAACTGTCTCAAAAAATGGAGAATGAAAAGACAGACCTTGTTGGAATGGCTCTTTTCATTTCTTCTGGTACTGT
TTCTGTACCTATTTTTCTCCAATTTACATCAAGTTCATGACACTCCTCAAATGTCTTCAATGGATCTGGGACGTGTAGATAGTTTTAATG
ATACTAATTATGTTATTGCATTTGCACCTGAATCCAAAACTACCCAAGAGATAATGAACAAAGTGGCTTCAGCCCCATTCCTAAAAGGAA
GAACAATCATGGGGTGGCCTGATGAAAAAAGCATGGATGAATTGGATTTGAACTATTCAATAGACGCAGTGAGAGTCATCTTTACTGATA
CCTTCTCCTACCATTTGAAGTTTTCTTGGGGACATAGAATCCCCATGATGAAAGAGCACAGAGACCATTCAGCTCACTGTCAAGCAGTGA
ATGAAAAAATGAAGTGTGAAGGTTCAGAGTTCTGGGAGAAAGGCTTTGTAGCTTTTCAAGCTGCCATTAATGCTGCTATCATAGAAATCG
CAACAAATCATTCAGTGATGGAACAGCTGATGTCAGTTACTGGTGTACATATGAAGATATTACCTTTTGTTGCCCAAGGAGGAGTTGCAA
CTGATTTTTTCATTTTCTTTTGCATTATTTCTTTTTCTACATTTATATACTATGTATCAGTCAATGTTACACAAGAAAGACAATACATTA
CGTCATTGATGACAATGATGGGACTCCGAGAGTCAGCATTCTGGCTTTCCTGGGGTTTGATGTATGCTGGCTTCATCCTTATCATGGCCA
CTTTAATGGCTCTTATTGTAAAATCTGCACAAATTGTCGTCCTGACTGGTTTTGTGATGGTCTTCACCCTCTTTCTCCTCTATGGCCTGT
CTTTGATAACTTTAGCTTTCCTGATGAGTGTGTTGATAAAGAAACCTTTCCTTACGGGCTTGGTTGTGTTTCTCCTTATTGTCTTTTGGG
GGATCCTGGGATTCCCAGCATTGTATACACGTCTTCCTGCATTTTTGGAATGGACTTTGTGTCTTCTTAGCCCCTTTGCCTTCACTGTTG
GGATGGCCCAGCTTATACATTTGGACTATGATGTGAATTCTAATGCCCACTTGGATTCTTCACAAAATCCATACCTCATAATAGCTACTC
TTTTCATGTTGGTTTTTGACACCCTTCTGTATTTGGTATTGACATTATATTTTGACAAAATTTTGCCCGCTGAATATGGACATCGATGTT
CTCCCTTGTTTTTCCTGAAATCCTGTTTTTGGTTTCAACACGGAAGGGCTAATCATGTGGTCCTTGAGAATGAAACAGATTCTGATCCTA
CACCTAATGACTGTTTTGAACCAGTGTCTCCAGAATTCTGTGGGAAAGAAGCCATCAGAATCAAAAATCTTAAAAAAGAATATGCAGGGA
AGTGTGAGAGAGTAGAAGCTTTGAAAGGTGTGGTGTTTGACATATATGAAGGCCAGATCACTGCCCTCCTTGGTCACAGTGGAGCTGGAA
AAACTACCCTGTTAAACATACTTAGTGGGTTGTCAGTTCCAACATCAGGTTCAGTCACTGTCTATAATCACACACTTTCAAGAATGGCTG
ATATAGAAAATATCAGCAAGTTCACTGGATTTTGTCCACAATCCAATGTGCAATTTGGATTTCTCACTGTGAAAGAAAACCTCAGGCTGT
TTGCTAAAATAAAAGGGATTTTGCCACATGAAGTGGAGAAAGAGGTACAACGAGTTGTACAGGAATTAGAAATGGAAAATATTCAAGACA
TCCTTGCTCAAAACTTAAGTGGTGGACAAAATAGGAAACTAACTTTTGGGATTGCCATTTTAGGAGATCCTCAAGTTTTGCTATTGGATG
AACCGACTGCTGGATTGGATCCTCTTTCAAGGCACCGAATATGGAATCTCCTGAAAGAGGGGAAATCAGACAGAGTAATTCTCTTCAGCA
CCCAGTTTATAGATGAGGCTGACATTCTGGCGGACAGGAAGGTGTTCATATCCAATGGGAAGCTGAAGTGTGCAGGCTCTTCTCTGTTCC
TTAAGAAGAAATGGGGCATAGGCTACCATTTAAGTTTGCATCTGAATGAAAGGTGTGATCCAGAGAGTATAACATCACTGGTTAAGCAGC
ACATCTCTGATGCCAAATTGACAGCACAAAGTGAAGAAAAACTTGTATATATTTTGCCTTTGGAAAGGACAAACAAATTTCCAGGTTTTA
CAAGATGAATTAGAAAACCGTTCTAATCAGGTGCGATGTGCAGAGAAAAAATTACAACACAAAGAATTGGAGTCACAGGAACAGATAACT
TACATACGACAAGAATATGAAACAAAATTGAAAGGATTGATGCCAGCATCCCTAAGACAAGAACTTGAAGACACCATTTCCTCCCTAAAA
TCACAGGTTAATTTTCTGCAAAAGAGAGCTTCCATCCTTCAGGAAGAACTGACTACATATCAAGGCAGAAGGTAACTGCACGAGAGAATG
CAACGGATGCAATTTCCAGGCTGTGCTGTGGACTTCTTCCAGCAGGTTTGAAGATTTGGATATTGTAAACTGTGAGATCAGTGGCATTTT
TTAAATCCTTAAATGTAATTAAGATCATAAAAACATGCATCATTCATACACTAGTGGGGTGGTTTTATTTGTGTCTGCCTAAGTTATTTT
TTTAACATTCCTTTATTTCCGATTTTCATGTTTGTGTGCATTTGAGTATGTGCTGAGAACTGCTTATATTGGGCAAAGTGATTTCCTATG
ATATGCCTTGTTAATCCTTTTGCATAGAATTTTACCAGTTGCGTACGATCAAAATCACGTTTGTAGTATCATATCAAAAATTCTAACCTG

>In-frame_ENST00000370732_ENST00000535342_TCGA-DX-A3M1-01A_ABCA9_chr17_67020355_-_CEP112_chr17_63685336_length(amino acids)=764AA_start in transcript=143_stop in transcript=2437
MSKRRMSVGQQTWALLCKNCLKKWRMKRQTLLEWLFSFLLVLFLYLFFSNLHQVHDTPQMSSMDLGRVDSFNDTNYVIAFAPESKTTQEI
MNKVASAPFLKGRTIMGWPDEKSMDELDLNYSIDAVRVIFTDTFSYHLKFSWGHRIPMMKEHRDHSAHCQAVNEKMKCEGSEFWEKGFVA
FQAAINAAIIEIATNHSVMEQLMSVTGVHMKILPFVAQGGVATDFFIFFCIISFSTFIYYVSVNVTQERQYITSLMTMMGLRESAFWLSW
GLMYAGFILIMATLMALIVKSAQIVVLTGFVMVFTLFLLYGLSLITLAFLMSVLIKKPFLTGLVVFLLIVFWGILGFPALYTRLPAFLEW
TLCLLSPFAFTVGMAQLIHLDYDVNSNAHLDSSQNPYLIIATLFMLVFDTLLYLVLTLYFDKILPAEYGHRCSPLFFLKSCFWFQHGRAN
HVVLENETDSDPTPNDCFEPVSPEFCGKEAIRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGS
VTVYNHTLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQNLSGGQNRKLTFGI
AILGDPQVLLLDEPTAGLDPLSRHRIWNLLKEGKSDRVILFSTQFIDEADILADRKVFISNGKLKCAGSSLFLKKKWGIGYHLSLHLNER

--------------------------------------------------------------
>In-frame_ENST00000370732_ENST00000392769_TCGA-DX-A3M1-01A_ABCA9_chr17_67020355_-_CEP112_chr17_63685336_length(transcript)=3115nt_BP=2424nt
ATTCACAATGAATGTGAAATTAAAAGCATGATGTAGTAGTGACCCAAAAGGAATGTGAATTCTCCTCCAGAACATGCAGAGACCCATGGA
TGAACTGTGTTTCTAGATTTTTCCTCCAGCTTTCCTGAGAGAAACAGGTCAAAATGAGCAAGAGACGCATGAGCGTGGGTCAGCAAACAT
GGGCTCTTCTCTGCAAGAACTGTCTCAAAAAATGGAGAATGAAAAGACAGACCTTGTTGGAATGGCTCTTTTCATTTCTTCTGGTACTGT
TTCTGTACCTATTTTTCTCCAATTTACATCAAGTTCATGACACTCCTCAAATGTCTTCAATGGATCTGGGACGTGTAGATAGTTTTAATG
ATACTAATTATGTTATTGCATTTGCACCTGAATCCAAAACTACCCAAGAGATAATGAACAAAGTGGCTTCAGCCCCATTCCTAAAAGGAA
GAACAATCATGGGGTGGCCTGATGAAAAAAGCATGGATGAATTGGATTTGAACTATTCAATAGACGCAGTGAGAGTCATCTTTACTGATA
CCTTCTCCTACCATTTGAAGTTTTCTTGGGGACATAGAATCCCCATGATGAAAGAGCACAGAGACCATTCAGCTCACTGTCAAGCAGTGA
ATGAAAAAATGAAGTGTGAAGGTTCAGAGTTCTGGGAGAAAGGCTTTGTAGCTTTTCAAGCTGCCATTAATGCTGCTATCATAGAAATCG
CAACAAATCATTCAGTGATGGAACAGCTGATGTCAGTTACTGGTGTACATATGAAGATATTACCTTTTGTTGCCCAAGGAGGAGTTGCAA
CTGATTTTTTCATTTTCTTTTGCATTATTTCTTTTTCTACATTTATATACTATGTATCAGTCAATGTTACACAAGAAAGACAATACATTA
CGTCATTGATGACAATGATGGGACTCCGAGAGTCAGCATTCTGGCTTTCCTGGGGTTTGATGTATGCTGGCTTCATCCTTATCATGGCCA
CTTTAATGGCTCTTATTGTAAAATCTGCACAAATTGTCGTCCTGACTGGTTTTGTGATGGTCTTCACCCTCTTTCTCCTCTATGGCCTGT
CTTTGATAACTTTAGCTTTCCTGATGAGTGTGTTGATAAAGAAACCTTTCCTTACGGGCTTGGTTGTGTTTCTCCTTATTGTCTTTTGGG
GGATCCTGGGATTCCCAGCATTGTATACACGTCTTCCTGCATTTTTGGAATGGACTTTGTGTCTTCTTAGCCCCTTTGCCTTCACTGTTG
GGATGGCCCAGCTTATACATTTGGACTATGATGTGAATTCTAATGCCCACTTGGATTCTTCACAAAATCCATACCTCATAATAGCTACTC
TTTTCATGTTGGTTTTTGACACCCTTCTGTATTTGGTATTGACATTATATTTTGACAAAATTTTGCCCGCTGAATATGGACATCGATGTT
CTCCCTTGTTTTTCCTGAAATCCTGTTTTTGGTTTCAACACGGAAGGGCTAATCATGTGGTCCTTGAGAATGAAACAGATTCTGATCCTA
CACCTAATGACTGTTTTGAACCAGTGTCTCCAGAATTCTGTGGGAAAGAAGCCATCAGAATCAAAAATCTTAAAAAAGAATATGCAGGGA
AGTGTGAGAGAGTAGAAGCTTTGAAAGGTGTGGTGTTTGACATATATGAAGGCCAGATCACTGCCCTCCTTGGTCACAGTGGAGCTGGAA
AAACTACCCTGTTAAACATACTTAGTGGGTTGTCAGTTCCAACATCAGGTTCAGTCACTGTCTATAATCACACACTTTCAAGAATGGCTG
ATATAGAAAATATCAGCAAGTTCACTGGATTTTGTCCACAATCCAATGTGCAATTTGGATTTCTCACTGTGAAAGAAAACCTCAGGCTGT
TTGCTAAAATAAAAGGGATTTTGCCACATGAAGTGGAGAAAGAGGTACAACGAGTTGTACAGGAATTAGAAATGGAAAATATTCAAGACA
TCCTTGCTCAAAACTTAAGTGGTGGACAAAATAGGAAACTAACTTTTGGGATTGCCATTTTAGGAGATCCTCAAGTTTTGCTATTGGATG
AACCGACTGCTGGATTGGATCCTCTTTCAAGGCACCGAATATGGAATCTCCTGAAAGAGGGGAAATCAGACAGAGTAATTCTCTTCAGCA
CCCAGTTTATAGATGAGGCTGACATTCTGGCGGACAGGAAGGTGTTCATATCCAATGGGAAGCTGAAGTGTGCAGGCTCTTCTCTGTTCC
TTAAGAAGAAATGGGGCATAGGCTACCATTTAAGTTTGCATCTGAATGAAAGGTGTGATCCAGAGAGTATAACATCACTGGTTAAGCAGC
ACATCTCTGATGCCAAATTGACAGCACAAAGTGAAGAAAAACTTGTATATATTTTGCCTTTGGAAAGGACAAACAAATTTCCAGGTTTTA
CAAGATGAATTAGAAAACCGTTCTAATCAGGTGCGATGTGCAGAGAAAAAATTACAACACAAAGAATTGGAGTCACAGGAACAGATAACT
TACATACGACAAGAATATGAAACAAAATTGAAAGGATTGATGCCAGCATCCCTAAGACAAGAACTTGAAGACACCATTTCCTCCCTAAAA
TCACAGGTTAATTTTCTGCAAAAGAGAGCTTCCATCCTTCAGGAAGAACTGACTACATATCAAGGCAGAAGGTAACTGCACGAGAGAATG
CAACGGATGCAATTTCCAGGCTGTGCTGTGGACTTCTTCCAGCAGGTTTGAAGATTTGGATATTGTAAACTGTGAGATCAGTGGCATTTT
TTAAATCCTTAAATGTAATTAAGATCATAAAAACATGCATCATTCATACACTAGTGGGGTGGTTTTATTTGTGTCTGCCTAAGTTATTTT
TTTAACATTCCTTTATTTCCGATTTTCATGTTTGTGTGCATTTGAGTATGTGCTGAGAACTGCTTATATTGGGCAAAGTGATTTCCTATG
ATATGCCTTGTTAATCCTTTTGCATAGAATTTTACCAGTTGCGTACGATCAAAATCACGTTTGTAGTATCATATCAAAAATTCTAACCTG

>In-frame_ENST00000370732_ENST00000392769_TCGA-DX-A3M1-01A_ABCA9_chr17_67020355_-_CEP112_chr17_63685336_length(amino acids)=764AA_start in transcript=143_stop in transcript=2437
MSKRRMSVGQQTWALLCKNCLKKWRMKRQTLLEWLFSFLLVLFLYLFFSNLHQVHDTPQMSSMDLGRVDSFNDTNYVIAFAPESKTTQEI
MNKVASAPFLKGRTIMGWPDEKSMDELDLNYSIDAVRVIFTDTFSYHLKFSWGHRIPMMKEHRDHSAHCQAVNEKMKCEGSEFWEKGFVA
FQAAINAAIIEIATNHSVMEQLMSVTGVHMKILPFVAQGGVATDFFIFFCIISFSTFIYYVSVNVTQERQYITSLMTMMGLRESAFWLSW
GLMYAGFILIMATLMALIVKSAQIVVLTGFVMVFTLFLLYGLSLITLAFLMSVLIKKPFLTGLVVFLLIVFWGILGFPALYTRLPAFLEW
TLCLLSPFAFTVGMAQLIHLDYDVNSNAHLDSSQNPYLIIATLFMLVFDTLLYLVLTLYFDKILPAEYGHRCSPLFFLKSCFWFQHGRAN
HVVLENETDSDPTPNDCFEPVSPEFCGKEAIRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGS
VTVYNHTLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQNLSGGQNRKLTFGI
AILGDPQVLLLDEPTAGLDPLSRHRIWNLLKEGKSDRVILFSTQFIDEADILADRKVFISNGKLKCAGSSLFLKKKWGIGYHLSLHLNER

--------------------------------------------------------------
>In-frame_ENST00000370732_ENST00000541355_TCGA-DX-A3M1-01A_ABCA9_chr17_67020355_-_CEP112_chr17_63685336_length(transcript)=2835nt_BP=2424nt
ATTCACAATGAATGTGAAATTAAAAGCATGATGTAGTAGTGACCCAAAAGGAATGTGAATTCTCCTCCAGAACATGCAGAGACCCATGGA
TGAACTGTGTTTCTAGATTTTTCCTCCAGCTTTCCTGAGAGAAACAGGTCAAAATGAGCAAGAGACGCATGAGCGTGGGTCAGCAAACAT
GGGCTCTTCTCTGCAAGAACTGTCTCAAAAAATGGAGAATGAAAAGACAGACCTTGTTGGAATGGCTCTTTTCATTTCTTCTGGTACTGT
TTCTGTACCTATTTTTCTCCAATTTACATCAAGTTCATGACACTCCTCAAATGTCTTCAATGGATCTGGGACGTGTAGATAGTTTTAATG
ATACTAATTATGTTATTGCATTTGCACCTGAATCCAAAACTACCCAAGAGATAATGAACAAAGTGGCTTCAGCCCCATTCCTAAAAGGAA
GAACAATCATGGGGTGGCCTGATGAAAAAAGCATGGATGAATTGGATTTGAACTATTCAATAGACGCAGTGAGAGTCATCTTTACTGATA
CCTTCTCCTACCATTTGAAGTTTTCTTGGGGACATAGAATCCCCATGATGAAAGAGCACAGAGACCATTCAGCTCACTGTCAAGCAGTGA
ATGAAAAAATGAAGTGTGAAGGTTCAGAGTTCTGGGAGAAAGGCTTTGTAGCTTTTCAAGCTGCCATTAATGCTGCTATCATAGAAATCG
CAACAAATCATTCAGTGATGGAACAGCTGATGTCAGTTACTGGTGTACATATGAAGATATTACCTTTTGTTGCCCAAGGAGGAGTTGCAA
CTGATTTTTTCATTTTCTTTTGCATTATTTCTTTTTCTACATTTATATACTATGTATCAGTCAATGTTACACAAGAAAGACAATACATTA
CGTCATTGATGACAATGATGGGACTCCGAGAGTCAGCATTCTGGCTTTCCTGGGGTTTGATGTATGCTGGCTTCATCCTTATCATGGCCA
CTTTAATGGCTCTTATTGTAAAATCTGCACAAATTGTCGTCCTGACTGGTTTTGTGATGGTCTTCACCCTCTTTCTCCTCTATGGCCTGT
CTTTGATAACTTTAGCTTTCCTGATGAGTGTGTTGATAAAGAAACCTTTCCTTACGGGCTTGGTTGTGTTTCTCCTTATTGTCTTTTGGG
GGATCCTGGGATTCCCAGCATTGTATACACGTCTTCCTGCATTTTTGGAATGGACTTTGTGTCTTCTTAGCCCCTTTGCCTTCACTGTTG
GGATGGCCCAGCTTATACATTTGGACTATGATGTGAATTCTAATGCCCACTTGGATTCTTCACAAAATCCATACCTCATAATAGCTACTC
TTTTCATGTTGGTTTTTGACACCCTTCTGTATTTGGTATTGACATTATATTTTGACAAAATTTTGCCCGCTGAATATGGACATCGATGTT
CTCCCTTGTTTTTCCTGAAATCCTGTTTTTGGTTTCAACACGGAAGGGCTAATCATGTGGTCCTTGAGAATGAAACAGATTCTGATCCTA
CACCTAATGACTGTTTTGAACCAGTGTCTCCAGAATTCTGTGGGAAAGAAGCCATCAGAATCAAAAATCTTAAAAAAGAATATGCAGGGA
AGTGTGAGAGAGTAGAAGCTTTGAAAGGTGTGGTGTTTGACATATATGAAGGCCAGATCACTGCCCTCCTTGGTCACAGTGGAGCTGGAA
AAACTACCCTGTTAAACATACTTAGTGGGTTGTCAGTTCCAACATCAGGTTCAGTCACTGTCTATAATCACACACTTTCAAGAATGGCTG
ATATAGAAAATATCAGCAAGTTCACTGGATTTTGTCCACAATCCAATGTGCAATTTGGATTTCTCACTGTGAAAGAAAACCTCAGGCTGT
TTGCTAAAATAAAAGGGATTTTGCCACATGAAGTGGAGAAAGAGGTACAACGAGTTGTACAGGAATTAGAAATGGAAAATATTCAAGACA
TCCTTGCTCAAAACTTAAGTGGTGGACAAAATAGGAAACTAACTTTTGGGATTGCCATTTTAGGAGATCCTCAAGTTTTGCTATTGGATG
AACCGACTGCTGGATTGGATCCTCTTTCAAGGCACCGAATATGGAATCTCCTGAAAGAGGGGAAATCAGACAGAGTAATTCTCTTCAGCA
CCCAGTTTATAGATGAGGCTGACATTCTGGCGGACAGGAAGGTGTTCATATCCAATGGGAAGCTGAAGTGTGCAGGCTCTTCTCTGTTCC
TTAAGAAGAAATGGGGCATAGGCTACCATTTAAGTTTGCATCTGAATGAAAGGTGTGATCCAGAGAGTATAACATCACTGGTTAAGCAGC
ACATCTCTGATGCCAAATTGACAGCACAAAGTGAAGAAAAACTTGTATATATTTTGCCTTTGGAAAGGACAAACAAATTTCCAGGTTTTA
CAAGATGAATTAGAAAACCGTTCTAATCAGGTGCGATGTGCAGAGAAAAAATTACAACACAAAGAATTGGAGTCACAGGAACAGATAACT
TACATACGACAAGAATATGAAACAAAATTGAAAGGATTGATGCCAGCATCCCTAAGACAAGAACTTGAAGACACCATTTCCTCCCTAAAA
TCACAGGTTAATTTTCTGCAAAAGAGAGCTTCCATCCTTCAGGAAGAACTGACTACATATCAAGGCAGAAGGTAACTGCACGAGAGAATG
CAACGGATGCAATTTCCAGGCTGTGCTGTGGACTTCTTCCAGCAGGTTTGAAGATTTGGATATTGTAAACTGTGAGATCAGTGGCATTTT

>In-frame_ENST00000370732_ENST00000541355_TCGA-DX-A3M1-01A_ABCA9_chr17_67020355_-_CEP112_chr17_63685336_length(amino acids)=764AA_start in transcript=143_stop in transcript=2437
MSKRRMSVGQQTWALLCKNCLKKWRMKRQTLLEWLFSFLLVLFLYLFFSNLHQVHDTPQMSSMDLGRVDSFNDTNYVIAFAPESKTTQEI
MNKVASAPFLKGRTIMGWPDEKSMDELDLNYSIDAVRVIFTDTFSYHLKFSWGHRIPMMKEHRDHSAHCQAVNEKMKCEGSEFWEKGFVA
FQAAINAAIIEIATNHSVMEQLMSVTGVHMKILPFVAQGGVATDFFIFFCIISFSTFIYYVSVNVTQERQYITSLMTMMGLRESAFWLSW
GLMYAGFILIMATLMALIVKSAQIVVLTGFVMVFTLFLLYGLSLITLAFLMSVLIKKPFLTGLVVFLLIVFWGILGFPALYTRLPAFLEW
TLCLLSPFAFTVGMAQLIHLDYDVNSNAHLDSSQNPYLIIATLFMLVFDTLLYLVLTLYFDKILPAEYGHRCSPLFFLKSCFWFQHGRAN
HVVLENETDSDPTPNDCFEPVSPEFCGKEAIRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGS
VTVYNHTLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQNLSGGQNRKLTFGI
AILGDPQVLLLDEPTAGLDPLSRHRIWNLLKEGKSDRVILFSTQFIDEADILADRKVFISNGKLKCAGSSLFLKKKWGIGYHLSLHLNER

--------------------------------------------------------------
>In-frame_ENST00000370732_ENST00000537949_TCGA-DX-A3M1-01A_ABCA9_chr17_67020355_-_CEP112_chr17_63685336_length(transcript)=2743nt_BP=2424nt
ATTCACAATGAATGTGAAATTAAAAGCATGATGTAGTAGTGACCCAAAAGGAATGTGAATTCTCCTCCAGAACATGCAGAGACCCATGGA
TGAACTGTGTTTCTAGATTTTTCCTCCAGCTTTCCTGAGAGAAACAGGTCAAAATGAGCAAGAGACGCATGAGCGTGGGTCAGCAAACAT
GGGCTCTTCTCTGCAAGAACTGTCTCAAAAAATGGAGAATGAAAAGACAGACCTTGTTGGAATGGCTCTTTTCATTTCTTCTGGTACTGT
TTCTGTACCTATTTTTCTCCAATTTACATCAAGTTCATGACACTCCTCAAATGTCTTCAATGGATCTGGGACGTGTAGATAGTTTTAATG
ATACTAATTATGTTATTGCATTTGCACCTGAATCCAAAACTACCCAAGAGATAATGAACAAAGTGGCTTCAGCCCCATTCCTAAAAGGAA
GAACAATCATGGGGTGGCCTGATGAAAAAAGCATGGATGAATTGGATTTGAACTATTCAATAGACGCAGTGAGAGTCATCTTTACTGATA
CCTTCTCCTACCATTTGAAGTTTTCTTGGGGACATAGAATCCCCATGATGAAAGAGCACAGAGACCATTCAGCTCACTGTCAAGCAGTGA
ATGAAAAAATGAAGTGTGAAGGTTCAGAGTTCTGGGAGAAAGGCTTTGTAGCTTTTCAAGCTGCCATTAATGCTGCTATCATAGAAATCG
CAACAAATCATTCAGTGATGGAACAGCTGATGTCAGTTACTGGTGTACATATGAAGATATTACCTTTTGTTGCCCAAGGAGGAGTTGCAA
CTGATTTTTTCATTTTCTTTTGCATTATTTCTTTTTCTACATTTATATACTATGTATCAGTCAATGTTACACAAGAAAGACAATACATTA
CGTCATTGATGACAATGATGGGACTCCGAGAGTCAGCATTCTGGCTTTCCTGGGGTTTGATGTATGCTGGCTTCATCCTTATCATGGCCA
CTTTAATGGCTCTTATTGTAAAATCTGCACAAATTGTCGTCCTGACTGGTTTTGTGATGGTCTTCACCCTCTTTCTCCTCTATGGCCTGT
CTTTGATAACTTTAGCTTTCCTGATGAGTGTGTTGATAAAGAAACCTTTCCTTACGGGCTTGGTTGTGTTTCTCCTTATTGTCTTTTGGG
GGATCCTGGGATTCCCAGCATTGTATACACGTCTTCCTGCATTTTTGGAATGGACTTTGTGTCTTCTTAGCCCCTTTGCCTTCACTGTTG
GGATGGCCCAGCTTATACATTTGGACTATGATGTGAATTCTAATGCCCACTTGGATTCTTCACAAAATCCATACCTCATAATAGCTACTC
TTTTCATGTTGGTTTTTGACACCCTTCTGTATTTGGTATTGACATTATATTTTGACAAAATTTTGCCCGCTGAATATGGACATCGATGTT
CTCCCTTGTTTTTCCTGAAATCCTGTTTTTGGTTTCAACACGGAAGGGCTAATCATGTGGTCCTTGAGAATGAAACAGATTCTGATCCTA
CACCTAATGACTGTTTTGAACCAGTGTCTCCAGAATTCTGTGGGAAAGAAGCCATCAGAATCAAAAATCTTAAAAAAGAATATGCAGGGA
AGTGTGAGAGAGTAGAAGCTTTGAAAGGTGTGGTGTTTGACATATATGAAGGCCAGATCACTGCCCTCCTTGGTCACAGTGGAGCTGGAA
AAACTACCCTGTTAAACATACTTAGTGGGTTGTCAGTTCCAACATCAGGTTCAGTCACTGTCTATAATCACACACTTTCAAGAATGGCTG
ATATAGAAAATATCAGCAAGTTCACTGGATTTTGTCCACAATCCAATGTGCAATTTGGATTTCTCACTGTGAAAGAAAACCTCAGGCTGT
TTGCTAAAATAAAAGGGATTTTGCCACATGAAGTGGAGAAAGAGGTACAACGAGTTGTACAGGAATTAGAAATGGAAAATATTCAAGACA
TCCTTGCTCAAAACTTAAGTGGTGGACAAAATAGGAAACTAACTTTTGGGATTGCCATTTTAGGAGATCCTCAAGTTTTGCTATTGGATG
AACCGACTGCTGGATTGGATCCTCTTTCAAGGCACCGAATATGGAATCTCCTGAAAGAGGGGAAATCAGACAGAGTAATTCTCTTCAGCA
CCCAGTTTATAGATGAGGCTGACATTCTGGCGGACAGGAAGGTGTTCATATCCAATGGGAAGCTGAAGTGTGCAGGCTCTTCTCTGTTCC
TTAAGAAGAAATGGGGCATAGGCTACCATTTAAGTTTGCATCTGAATGAAAGGTGTGATCCAGAGAGTATAACATCACTGGTTAAGCAGC
ACATCTCTGATGCCAAATTGACAGCACAAAGTGAAGAAAAACTTGTATATATTTTGCCTTTGGAAAGGACAAACAAATTTCCAGGTTTTA
CAAGATGAATTAGAAAACCGTTCTAATCAGGTGCGATGTGCAGAGAAAAAATTACAACACAAAGAATTGGAGTCACAGGAACAGATAACT
TACATACGACAAGAATATGAAACAAAATTGAAAGGATTGATGCCAGCATCCCTAAGACAAGAACTTGAAGACACCATTTCCTCCCTAAAA
TCACAGGTTAATTTTCTGCAAAAGAGAGCTTCCATCCTTCAGGAAGAACTGACTACATATCAAGGCAGAAGGTAACTGCACGAGAGAATG

>In-frame_ENST00000370732_ENST00000537949_TCGA-DX-A3M1-01A_ABCA9_chr17_67020355_-_CEP112_chr17_63685336_length(amino acids)=764AA_start in transcript=143_stop in transcript=2437
MSKRRMSVGQQTWALLCKNCLKKWRMKRQTLLEWLFSFLLVLFLYLFFSNLHQVHDTPQMSSMDLGRVDSFNDTNYVIAFAPESKTTQEI
MNKVASAPFLKGRTIMGWPDEKSMDELDLNYSIDAVRVIFTDTFSYHLKFSWGHRIPMMKEHRDHSAHCQAVNEKMKCEGSEFWEKGFVA
FQAAINAAIIEIATNHSVMEQLMSVTGVHMKILPFVAQGGVATDFFIFFCIISFSTFIYYVSVNVTQERQYITSLMTMMGLRESAFWLSW
GLMYAGFILIMATLMALIVKSAQIVVLTGFVMVFTLFLLYGLSLITLAFLMSVLIKKPFLTGLVVFLLIVFWGILGFPALYTRLPAFLEW
TLCLLSPFAFTVGMAQLIHLDYDVNSNAHLDSSQNPYLIIATLFMLVFDTLLYLVLTLYFDKILPAEYGHRCSPLFFLKSCFWFQHGRAN
HVVLENETDSDPTPNDCFEPVSPEFCGKEAIRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGS
VTVYNHTLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQNLSGGQNRKLTFGI
AILGDPQVLLLDEPTAGLDPLSRHRIWNLLKEGKSDRVILFSTQFIDEADILADRKVFISNGKLKCAGSSLFLKKKWGIGYHLSLHLNER

--------------------------------------------------------------
>In-frame_ENST00000370732_ENST00000317442_TCGA-DX-A3M1-01A_ABCA9_chr17_67020355_-_CEP112_chr17_63685336_length(transcript)=2840nt_BP=2424nt
ATTCACAATGAATGTGAAATTAAAAGCATGATGTAGTAGTGACCCAAAAGGAATGTGAATTCTCCTCCAGAACATGCAGAGACCCATGGA
TGAACTGTGTTTCTAGATTTTTCCTCCAGCTTTCCTGAGAGAAACAGGTCAAAATGAGCAAGAGACGCATGAGCGTGGGTCAGCAAACAT
GGGCTCTTCTCTGCAAGAACTGTCTCAAAAAATGGAGAATGAAAAGACAGACCTTGTTGGAATGGCTCTTTTCATTTCTTCTGGTACTGT
TTCTGTACCTATTTTTCTCCAATTTACATCAAGTTCATGACACTCCTCAAATGTCTTCAATGGATCTGGGACGTGTAGATAGTTTTAATG
ATACTAATTATGTTATTGCATTTGCACCTGAATCCAAAACTACCCAAGAGATAATGAACAAAGTGGCTTCAGCCCCATTCCTAAAAGGAA
GAACAATCATGGGGTGGCCTGATGAAAAAAGCATGGATGAATTGGATTTGAACTATTCAATAGACGCAGTGAGAGTCATCTTTACTGATA
CCTTCTCCTACCATTTGAAGTTTTCTTGGGGACATAGAATCCCCATGATGAAAGAGCACAGAGACCATTCAGCTCACTGTCAAGCAGTGA
ATGAAAAAATGAAGTGTGAAGGTTCAGAGTTCTGGGAGAAAGGCTTTGTAGCTTTTCAAGCTGCCATTAATGCTGCTATCATAGAAATCG
CAACAAATCATTCAGTGATGGAACAGCTGATGTCAGTTACTGGTGTACATATGAAGATATTACCTTTTGTTGCCCAAGGAGGAGTTGCAA
CTGATTTTTTCATTTTCTTTTGCATTATTTCTTTTTCTACATTTATATACTATGTATCAGTCAATGTTACACAAGAAAGACAATACATTA
CGTCATTGATGACAATGATGGGACTCCGAGAGTCAGCATTCTGGCTTTCCTGGGGTTTGATGTATGCTGGCTTCATCCTTATCATGGCCA
CTTTAATGGCTCTTATTGTAAAATCTGCACAAATTGTCGTCCTGACTGGTTTTGTGATGGTCTTCACCCTCTTTCTCCTCTATGGCCTGT
CTTTGATAACTTTAGCTTTCCTGATGAGTGTGTTGATAAAGAAACCTTTCCTTACGGGCTTGGTTGTGTTTCTCCTTATTGTCTTTTGGG
GGATCCTGGGATTCCCAGCATTGTATACACGTCTTCCTGCATTTTTGGAATGGACTTTGTGTCTTCTTAGCCCCTTTGCCTTCACTGTTG
GGATGGCCCAGCTTATACATTTGGACTATGATGTGAATTCTAATGCCCACTTGGATTCTTCACAAAATCCATACCTCATAATAGCTACTC
TTTTCATGTTGGTTTTTGACACCCTTCTGTATTTGGTATTGACATTATATTTTGACAAAATTTTGCCCGCTGAATATGGACATCGATGTT
CTCCCTTGTTTTTCCTGAAATCCTGTTTTTGGTTTCAACACGGAAGGGCTAATCATGTGGTCCTTGAGAATGAAACAGATTCTGATCCTA
CACCTAATGACTGTTTTGAACCAGTGTCTCCAGAATTCTGTGGGAAAGAAGCCATCAGAATCAAAAATCTTAAAAAAGAATATGCAGGGA
AGTGTGAGAGAGTAGAAGCTTTGAAAGGTGTGGTGTTTGACATATATGAAGGCCAGATCACTGCCCTCCTTGGTCACAGTGGAGCTGGAA
AAACTACCCTGTTAAACATACTTAGTGGGTTGTCAGTTCCAACATCAGGTTCAGTCACTGTCTATAATCACACACTTTCAAGAATGGCTG
ATATAGAAAATATCAGCAAGTTCACTGGATTTTGTCCACAATCCAATGTGCAATTTGGATTTCTCACTGTGAAAGAAAACCTCAGGCTGT
TTGCTAAAATAAAAGGGATTTTGCCACATGAAGTGGAGAAAGAGGTACAACGAGTTGTACAGGAATTAGAAATGGAAAATATTCAAGACA
TCCTTGCTCAAAACTTAAGTGGTGGACAAAATAGGAAACTAACTTTTGGGATTGCCATTTTAGGAGATCCTCAAGTTTTGCTATTGGATG
AACCGACTGCTGGATTGGATCCTCTTTCAAGGCACCGAATATGGAATCTCCTGAAAGAGGGGAAATCAGACAGAGTAATTCTCTTCAGCA
CCCAGTTTATAGATGAGGCTGACATTCTGGCGGACAGGAAGGTGTTCATATCCAATGGGAAGCTGAAGTGTGCAGGCTCTTCTCTGTTCC
TTAAGAAGAAATGGGGCATAGGCTACCATTTAAGTTTGCATCTGAATGAAAGGTGTGATCCAGAGAGTATAACATCACTGGTTAAGCAGC
ACATCTCTGATGCCAAATTGACAGCACAAAGTGAAGAAAAACTTGTATATATTTTGCCTTTGGAAAGGACAAACAAATTTCCAGGTTTTA
CAAGATGAATTAGAAAACCGTTCTAATCAGGTGCGATGTGCAGAGAAAAAATTACAACACAAAGAATTGGAGTCACAGGAACAGATAACT
TACATACGACAAGAATATGAAACAAAATTGAAAGGATTGATGCCAGCATCCCTAAGACAAGAACTTGAAGACACCATTTCCTCCCTAAAA
TCACAGGTTAATTTTCTGCAAAAGAGAGCTTCCATCCTTCAGGAAGAACTGACTACATATCAAGGCAGAAGGTAACTGCACGAGAGAATG
CAACGGATGCAATTTCCAGGCTGTGCTGTGGACTTCTTCCAGCAGGTTTGAAGATTTGGATATTGTAAACTGTGAGATCAGTGGCATTTT

>In-frame_ENST00000370732_ENST00000317442_TCGA-DX-A3M1-01A_ABCA9_chr17_67020355_-_CEP112_chr17_63685336_length(amino acids)=764AA_start in transcript=143_stop in transcript=2437
MSKRRMSVGQQTWALLCKNCLKKWRMKRQTLLEWLFSFLLVLFLYLFFSNLHQVHDTPQMSSMDLGRVDSFNDTNYVIAFAPESKTTQEI
MNKVASAPFLKGRTIMGWPDEKSMDELDLNYSIDAVRVIFTDTFSYHLKFSWGHRIPMMKEHRDHSAHCQAVNEKMKCEGSEFWEKGFVA
FQAAINAAIIEIATNHSVMEQLMSVTGVHMKILPFVAQGGVATDFFIFFCIISFSTFIYYVSVNVTQERQYITSLMTMMGLRESAFWLSW
GLMYAGFILIMATLMALIVKSAQIVVLTGFVMVFTLFLLYGLSLITLAFLMSVLIKKPFLTGLVVFLLIVFWGILGFPALYTRLPAFLEW
TLCLLSPFAFTVGMAQLIHLDYDVNSNAHLDSSQNPYLIIATLFMLVFDTLLYLVLTLYFDKILPAEYGHRCSPLFFLKSCFWFQHGRAN
HVVLENETDSDPTPNDCFEPVSPEFCGKEAIRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGS
VTVYNHTLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQNLSGGQNRKLTFGI
AILGDPQVLLLDEPTAGLDPLSRHRIWNLLKEGKSDRVILFSTQFIDEADILADRKVFISNGKLKCAGSSLFLKKKWGIGYHLSLHLNER

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ABCA9-CEP112


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABCA9-CEP112


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABCA9-CEP112


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneABCA9C0009402Colorectal Carcinoma1CTD_human
HgeneABCA9C0009404Colorectal Neoplasms1CTD_human