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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GOLGA4-RRM1 (FusionGDB2 ID:33789)

Fusion Gene Summary for GOLGA4-RRM1

check button Fusion gene summary
Fusion gene informationFusion gene name: GOLGA4-RRM1
Fusion gene ID: 33789
HgeneTgene
Gene symbol

GOLGA4

RRM1

Gene ID

2803

6240

Gene namegolgin A4ribonucleotide reductase catalytic subunit M1
SynonymsCRPF46|GCP2|GOLG|MU-RMS-40.18|p230R1|RIR1|RR1
Cytomap

3p22.2

11p15.4

Type of geneprotein-codingprotein-coding
Descriptiongolgin subfamily A member 4256 kDa golgin72.1 proteincentrosome-related protein F46golgi autoantigen, golgin subfamily a, 4golgin-240golgin-245protein 72.1trans-Golgi p230ribonucleoside-diphosphate reductase large subunitribonucleoside-diphosphate reductase subunit M1ribonucleotide reductase M1 polypeptideribonucleotide reductase, R1 subunit
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000361924, ENST00000435830, 
ENST00000444882, ENST00000356847, 
ENST00000300738, ENST00000423050, 
ENST00000534285, ENST00000537197, 
ENST00000528470, 
Fusion gene scores* DoF score24 X 16 X 11=42247 X 6 X 4=168
# samples 277
** MAII scorelog2(27/4224*10)=-3.96757852230762
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/168*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GOLGA4 [Title/Abstract] AND RRM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGOLGA4(37292975)-RRM1(4150304), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGOLGA4

GO:0043001

Golgi to plasma membrane protein transport

15265687

HgeneGOLGA4

GO:0045773

positive regulation of axon extension

22705394


check buttonFusion gene breakpoints across GOLGA4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across RRM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-G2-AA3F-01AGOLGA4chr3

37292975

+RRM1chr11

4150304

+
ChimerDB4BLCATCGA-G2-AA3F-01AGOLGA4chr3

37292975

-RRM1chr11

4150304

+


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Fusion Gene ORF analysis for GOLGA4-RRM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000361924ENST00000300738GOLGA4chr3

37292975

+RRM1chr11

4150304

+
In-frameENST00000361924ENST00000423050GOLGA4chr3

37292975

+RRM1chr11

4150304

+
In-frameENST00000361924ENST00000534285GOLGA4chr3

37292975

+RRM1chr11

4150304

+
In-frameENST00000361924ENST00000537197GOLGA4chr3

37292975

+RRM1chr11

4150304

+
5CDS-intronENST00000361924ENST00000528470GOLGA4chr3

37292975

+RRM1chr11

4150304

+
intron-3CDSENST00000435830ENST00000300738GOLGA4chr3

37292975

+RRM1chr11

4150304

+
intron-3CDSENST00000435830ENST00000423050GOLGA4chr3

37292975

+RRM1chr11

4150304

+
intron-3CDSENST00000435830ENST00000534285GOLGA4chr3

37292975

+RRM1chr11

4150304

+
intron-3CDSENST00000435830ENST00000537197GOLGA4chr3

37292975

+RRM1chr11

4150304

+
intron-intronENST00000435830ENST00000528470GOLGA4chr3

37292975

+RRM1chr11

4150304

+
In-frameENST00000444882ENST00000300738GOLGA4chr3

37292975

+RRM1chr11

4150304

+
In-frameENST00000444882ENST00000423050GOLGA4chr3

37292975

+RRM1chr11

4150304

+
In-frameENST00000444882ENST00000534285GOLGA4chr3

37292975

+RRM1chr11

4150304

+
In-frameENST00000444882ENST00000537197GOLGA4chr3

37292975

+RRM1chr11

4150304

+
5CDS-intronENST00000444882ENST00000528470GOLGA4chr3

37292975

+RRM1chr11

4150304

+
In-frameENST00000356847ENST00000300738GOLGA4chr3

37292975

+RRM1chr11

4150304

+
In-frameENST00000356847ENST00000423050GOLGA4chr3

37292975

+RRM1chr11

4150304

+
In-frameENST00000356847ENST00000534285GOLGA4chr3

37292975

+RRM1chr11

4150304

+
In-frameENST00000356847ENST00000537197GOLGA4chr3

37292975

+RRM1chr11

4150304

+
5CDS-intronENST00000356847ENST00000528470GOLGA4chr3

37292975

+RRM1chr11

4150304

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000361924GOLGA4chr337292975+ENST00000300738RRM1chr114150304+17165363741222282
ENST00000361924GOLGA4chr337292975+ENST00000423050RRM1chr114150304+17155363741222282
ENST00000361924GOLGA4chr337292975+ENST00000534285RRM1chr114150304+12865363741222282
ENST00000361924GOLGA4chr337292975+ENST00000537197RRM1chr114150304+17155363741222282
ENST00000444882GOLGA4chr337292975+ENST00000300738RRM1chr114150304+16464663041152282
ENST00000444882GOLGA4chr337292975+ENST00000423050RRM1chr114150304+16454663041152282
ENST00000444882GOLGA4chr337292975+ENST00000534285RRM1chr114150304+12164663041152282
ENST00000444882GOLGA4chr337292975+ENST00000537197RRM1chr114150304+16454663041152282
ENST00000356847GOLGA4chr337292975+ENST00000300738RRM1chr114150304+16414612991147282
ENST00000356847GOLGA4chr337292975+ENST00000423050RRM1chr114150304+16404612991147282
ENST00000356847GOLGA4chr337292975+ENST00000534285RRM1chr114150304+12114612991147282
ENST00000356847GOLGA4chr337292975+ENST00000537197RRM1chr114150304+16404612991147282

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000361924ENST00000300738GOLGA4chr337292975+RRM1chr114150304+0.0039541660.99604577
ENST00000361924ENST00000423050GOLGA4chr337292975+RRM1chr114150304+0.0039277230.9960723
ENST00000361924ENST00000534285GOLGA4chr337292975+RRM1chr114150304+0.0069170850.9930829
ENST00000361924ENST00000537197GOLGA4chr337292975+RRM1chr114150304+0.0039277230.9960723
ENST00000444882ENST00000300738GOLGA4chr337292975+RRM1chr114150304+0.0044743020.99552566
ENST00000444882ENST00000423050GOLGA4chr337292975+RRM1chr114150304+0.004467430.9955325
ENST00000444882ENST00000534285GOLGA4chr337292975+RRM1chr114150304+0.0085717540.9914282
ENST00000444882ENST00000537197GOLGA4chr337292975+RRM1chr114150304+0.004467430.9955325
ENST00000356847ENST00000300738GOLGA4chr337292975+RRM1chr114150304+0.0044358430.9955642
ENST00000356847ENST00000423050GOLGA4chr337292975+RRM1chr114150304+0.0044306630.9955693
ENST00000356847ENST00000534285GOLGA4chr337292975+RRM1chr114150304+0.0083757150.9916243
ENST00000356847ENST00000537197GOLGA4chr337292975+RRM1chr114150304+0.0044306630.9955693

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Fusion Genomic Features for GOLGA4-RRM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
GOLGA4chr337292975+RRM1chr114150303+5.59E-060.9999944
GOLGA4chr337292975+RRM1chr114150303+5.59E-060.9999944

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GOLGA4-RRM1


check button Go to

FGviewer for the breakpoints of chr3:37292975-chr11:4150304

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRRM1chr3:37292975chr11:4150304ENST000003007381319604_607564.0793.0RegionGDP binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGOLGA4chr3:37292975chr11:4150304ENST00000356847+223133_218554.02244.0Coiled coilOntology_term=ECO:0000255
HgeneGOLGA4chr3:37292975chr11:4150304ENST00000361924+224133_218554.02306.3333333333335Coiled coilOntology_term=ECO:0000255
HgeneGOLGA4chr3:37292975chr11:4150304ENST00000356847+223252_209654.02244.0Compositional biasNote=Glu-rich
HgeneGOLGA4chr3:37292975chr11:4150304ENST00000361924+224252_209654.02306.3333333333335Compositional biasNote=Glu-rich
HgeneGOLGA4chr3:37292975chr11:4150304ENST00000356847+2232168_221554.02244.0DomainGRIP
HgeneGOLGA4chr3:37292975chr11:4150304ENST00000361924+2242168_221554.02306.3333333333335DomainGRIP
TgeneRRM1chr3:37292975chr11:4150304ENST0000030073813191_92564.0793.0DomainATP-cone
TgeneRRM1chr3:37292975chr11:4150304ENST00000300738131911_17564.0793.0Nucleotide bindingATP%3B allosteric activator
TgeneRRM1chr3:37292975chr11:4150304ENST000003007381319226_228564.0793.0Nucleotide bindingdTTP%3B allosteric effector that controls substrate specificity
TgeneRRM1chr3:37292975chr11:4150304ENST000003007381319263_264564.0793.0Nucleotide bindingdTTP%3B allosteric effector that controls substrate specificity
TgeneRRM1chr3:37292975chr11:4150304ENST0000030073813195_6564.0793.0Nucleotide bindingATP%3B allosteric activator


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Fusion Gene Sequence for GOLGA4-RRM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000361924_ENST00000300738_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1716nt_BP=536nt
ATGTGCGGGACCCGACATTGTGCTTGTCCCATCCGGTGCTCCGTAGTTAGCCTCTGTGAGCTCCACGTAGGCCGCGCAAGCGCCCTTGGC
GCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGCCAGTGGCACCCGGAAGAAAG
AGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAGACGGCGAGGCCCGGCCCCCG
CTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTTTCGTTGACACTCAGGACCGT
ACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGGCTCCTGCTCAGGCGT
CCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACACCCAATAGAGAGATTC
TTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGCAAAGTATGGTATAAGAAACA
GTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACCTTACACCAGCAACATCTATA
CTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGGCCTATGGCATGAAGAGATGA
AAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACTTTATAAAACTGTGTGGGAAA
TCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAACATCCACATTGCTGAGCCTA
ACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTTAAGGACAAGACCAGCGGCTA
ATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGAGAAGGAGAGGAACACAGCAG
CCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAGACCAGCATGTCTTCAGTAGC
CAAACTACTTCTTGAGCATAGATAGGTATAGTGGGTTTGCTTGAGGTGGTAAGGCTTTGCTGGACCCTGTTGCAGGCAAAAGGAGTAATT
GATTTAAAGTACTGTTAATGATGATAATGATTTTTTTTTTAAACTCATATATTGGGATTTTCACCAAAATAATGCTTTTGAAAAAAAGAA
AAAAAAAACGGATATATTGAGAATCAAAGTAGAAGTTTTAGGAATGCAAAATAAGTCATCTTGCATACAGGGAGTGGTTAAGTAAGGTTT
CATCACCCCTTTAGCACTGCTTTTCTGAAGACTTCAGTTTTGTTAAGGAGATTTAGTTTTACTGCTTTGACTGGTGGGTCTCTAGAAGCA
AAACTGAGTGATAACTCATGAGAAGTACTGATAGGACCTTTATCTGGATATGGTCCTATAGGTTATTCTGAAATAAAGATAAACATTTCT

>In-frame_ENST00000361924_ENST00000300738_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=374_stop in transcript=1222
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

--------------------------------------------------------------
>In-frame_ENST00000361924_ENST00000423050_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1715nt_BP=536nt
ATGTGCGGGACCCGACATTGTGCTTGTCCCATCCGGTGCTCCGTAGTTAGCCTCTGTGAGCTCCACGTAGGCCGCGCAAGCGCCCTTGGC
GCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGCCAGTGGCACCCGGAAGAAAG
AGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAGACGGCGAGGCCCGGCCCCCG
CTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTTTCGTTGACACTCAGGACCGT
ACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGGCTCCTGCTCAGGCGT
CCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACACCCAATAGAGAGATTC
TTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGCAAAGTATGGTATAAGAAACA
GTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACCTTACACCAGCAACATCTATA
CTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGGCCTATGGCATGAAGAGATGA
AAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACTTTATAAAACTGTGTGGGAAA
TCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAACATCCACATTGCTGAGCCTA
ACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTTAAGGACAAGACCAGCGGCTA
ATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGAGAAGGAGAGGAACACAGCAG
CCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAGACCAGCATGTCTTCAGTAGC
CAAACTACTTCTTGAGCATAGATAGGTATAGTGGGTTTGCTTGAGGTGGTAAGGCTTTGCTGGACCCTGTTGCAGGCAAAAGGAGTAATT
GATTTAAAGTACTGTTAATGATGATAATGATTTTTTTTTTAAACTCATATATTGGGATTTTCACCAAAATAATGCTTTTGAAAAAAAGAA
AAAAAAAACGGATATATTGAGAATCAAAGTAGAAGTTTTAGGAATGCAAAATAAGTCATCTTGCATACAGGGAGTGGTTAAGTAAGGTTT
CATCACCCCTTTAGCACTGCTTTTCTGAAGACTTCAGTTTTGTTAAGGAGATTTAGTTTTACTGCTTTGACTGGTGGGTCTCTAGAAGCA
AAACTGAGTGATAACTCATGAGAAGTACTGATAGGACCTTTATCTGGATATGGTCCTATAGGTTATTCTGAAATAAAGATAAACATTTCT

>In-frame_ENST00000361924_ENST00000423050_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=374_stop in transcript=1222
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

--------------------------------------------------------------
>In-frame_ENST00000361924_ENST00000534285_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1286nt_BP=536nt
ATGTGCGGGACCCGACATTGTGCTTGTCCCATCCGGTGCTCCGTAGTTAGCCTCTGTGAGCTCCACGTAGGCCGCGCAAGCGCCCTTGGC
GCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGCCAGTGGCACCCGGAAGAAAG
AGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAGACGGCGAGGCCCGGCCCCCG
CTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTTTCGTTGACACTCAGGACCGT
ACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGGCTCCTGCTCAGGCGT
CCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACACCCAATAGAGAGATTC
TTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGCAAAGTATGGTATAAGAAACA
GTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACCTTACACCAGCAACATCTATA
CTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGGCCTATGGCATGAAGAGATGA
AAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACTTTATAAAACTGTGTGGGAAA
TCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAACATCCACATTGCTGAGCCTA
ACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTTAAGGACAAGACCAGCGGCTA
ATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGAGAAGGAGAGGAACACAGCAG
CCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAGACCAGCATGTCTTCAGTAGC

>In-frame_ENST00000361924_ENST00000534285_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=374_stop in transcript=1222
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

--------------------------------------------------------------
>In-frame_ENST00000361924_ENST00000537197_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1715nt_BP=536nt
ATGTGCGGGACCCGACATTGTGCTTGTCCCATCCGGTGCTCCGTAGTTAGCCTCTGTGAGCTCCACGTAGGCCGCGCAAGCGCCCTTGGC
GCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGCCAGTGGCACCCGGAAGAAAG
AGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAGACGGCGAGGCCCGGCCCCCG
CTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTTTCGTTGACACTCAGGACCGT
ACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGGCTCCTGCTCAGGCGT
CCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACACCCAATAGAGAGATTC
TTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGCAAAGTATGGTATAAGAAACA
GTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACCTTACACCAGCAACATCTATA
CTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGGCCTATGGCATGAAGAGATGA
AAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACTTTATAAAACTGTGTGGGAAA
TCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAACATCCACATTGCTGAGCCTA
ACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTTAAGGACAAGACCAGCGGCTA
ATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGAGAAGGAGAGGAACACAGCAG
CCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAGACCAGCATGTCTTCAGTAGC
CAAACTACTTCTTGAGCATAGATAGGTATAGTGGGTTTGCTTGAGGTGGTAAGGCTTTGCTGGACCCTGTTGCAGGCAAAAGGAGTAATT
GATTTAAAGTACTGTTAATGATGATAATGATTTTTTTTTTAAACTCATATATTGGGATTTTCACCAAAATAATGCTTTTGAAAAAAAGAA
AAAAAAAACGGATATATTGAGAATCAAAGTAGAAGTTTTAGGAATGCAAAATAAGTCATCTTGCATACAGGGAGTGGTTAAGTAAGGTTT
CATCACCCCTTTAGCACTGCTTTTCTGAAGACTTCAGTTTTGTTAAGGAGATTTAGTTTTACTGCTTTGACTGGTGGGTCTCTAGAAGCA
AAACTGAGTGATAACTCATGAGAAGTACTGATAGGACCTTTATCTGGATATGGTCCTATAGGTTATTCTGAAATAAAGATAAACATTTCT

>In-frame_ENST00000361924_ENST00000537197_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=374_stop in transcript=1222
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

--------------------------------------------------------------
>In-frame_ENST00000444882_ENST00000300738_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1646nt_BP=466nt
GCCGCGCAAGCGCCCTTGGCGCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGC
CAGTGGCACCCGGAAGAAAGAGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAG
ACGGCGAGGCCCGGCCCCCGCTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTT
TCGTTGACACTCAGGACCGTACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGC
GCTGGCTCCTGCTCAGGCGTCCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGG
TACACCCAATAGAGAGATTCTTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGC
AAAGTATGGTATAAGAAACAGTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACC
TTACACCAGCAACATCTATACTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGG
CCTATGGCATGAAGAGATGAAAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACT
TTATAAAACTGTGTGGGAAATCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAA
CATCCACATTGCTGAGCCTAACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTT
AAGGACAAGACCAGCGGCTAATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGA
GAAGGAGAGGAACACAGCAGCCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAG
ACCAGCATGTCTTCAGTAGCCAAACTACTTCTTGAGCATAGATAGGTATAGTGGGTTTGCTTGAGGTGGTAAGGCTTTGCTGGACCCTGT
TGCAGGCAAAAGGAGTAATTGATTTAAAGTACTGTTAATGATGATAATGATTTTTTTTTTAAACTCATATATTGGGATTTTCACCAAAAT
AATGCTTTTGAAAAAAAGAAAAAAAAAACGGATATATTGAGAATCAAAGTAGAAGTTTTAGGAATGCAAAATAAGTCATCTTGCATACAG
GGAGTGGTTAAGTAAGGTTTCATCACCCCTTTAGCACTGCTTTTCTGAAGACTTCAGTTTTGTTAAGGAGATTTAGTTTTACTGCTTTGA
CTGGTGGGTCTCTAGAAGCAAAACTGAGTGATAACTCATGAGAAGTACTGATAGGACCTTTATCTGGATATGGTCCTATAGGTTATTCTG

>In-frame_ENST00000444882_ENST00000300738_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=304_stop in transcript=1152
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

--------------------------------------------------------------
>In-frame_ENST00000444882_ENST00000423050_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1645nt_BP=466nt
GCCGCGCAAGCGCCCTTGGCGCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGC
CAGTGGCACCCGGAAGAAAGAGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAG
ACGGCGAGGCCCGGCCCCCGCTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTT
TCGTTGACACTCAGGACCGTACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGC
GCTGGCTCCTGCTCAGGCGTCCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGG
TACACCCAATAGAGAGATTCTTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGC
AAAGTATGGTATAAGAAACAGTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACC
TTACACCAGCAACATCTATACTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGG
CCTATGGCATGAAGAGATGAAAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACT
TTATAAAACTGTGTGGGAAATCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAA
CATCCACATTGCTGAGCCTAACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTT
AAGGACAAGACCAGCGGCTAATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGA
GAAGGAGAGGAACACAGCAGCCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAG
ACCAGCATGTCTTCAGTAGCCAAACTACTTCTTGAGCATAGATAGGTATAGTGGGTTTGCTTGAGGTGGTAAGGCTTTGCTGGACCCTGT
TGCAGGCAAAAGGAGTAATTGATTTAAAGTACTGTTAATGATGATAATGATTTTTTTTTTAAACTCATATATTGGGATTTTCACCAAAAT
AATGCTTTTGAAAAAAAGAAAAAAAAAACGGATATATTGAGAATCAAAGTAGAAGTTTTAGGAATGCAAAATAAGTCATCTTGCATACAG
GGAGTGGTTAAGTAAGGTTTCATCACCCCTTTAGCACTGCTTTTCTGAAGACTTCAGTTTTGTTAAGGAGATTTAGTTTTACTGCTTTGA
CTGGTGGGTCTCTAGAAGCAAAACTGAGTGATAACTCATGAGAAGTACTGATAGGACCTTTATCTGGATATGGTCCTATAGGTTATTCTG

>In-frame_ENST00000444882_ENST00000423050_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=304_stop in transcript=1152
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

--------------------------------------------------------------
>In-frame_ENST00000444882_ENST00000534285_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1216nt_BP=466nt
GCCGCGCAAGCGCCCTTGGCGCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGC
CAGTGGCACCCGGAAGAAAGAGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAG
ACGGCGAGGCCCGGCCCCCGCTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTT
TCGTTGACACTCAGGACCGTACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGC
GCTGGCTCCTGCTCAGGCGTCCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGG
TACACCCAATAGAGAGATTCTTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGC
AAAGTATGGTATAAGAAACAGTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACC
TTACACCAGCAACATCTATACTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGG
CCTATGGCATGAAGAGATGAAAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACT
TTATAAAACTGTGTGGGAAATCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAA
CATCCACATTGCTGAGCCTAACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTT
AAGGACAAGACCAGCGGCTAATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGA
GAAGGAGAGGAACACAGCAGCCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAG

>In-frame_ENST00000444882_ENST00000534285_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=304_stop in transcript=1152
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

--------------------------------------------------------------
>In-frame_ENST00000444882_ENST00000537197_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1645nt_BP=466nt
GCCGCGCAAGCGCCCTTGGCGCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGC
CAGTGGCACCCGGAAGAAAGAGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAG
ACGGCGAGGCCCGGCCCCCGCTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTT
TCGTTGACACTCAGGACCGTACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGC
GCTGGCTCCTGCTCAGGCGTCCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGG
TACACCCAATAGAGAGATTCTTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGC
AAAGTATGGTATAAGAAACAGTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACC
TTACACCAGCAACATCTATACTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGG
CCTATGGCATGAAGAGATGAAAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACT
TTATAAAACTGTGTGGGAAATCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAA
CATCCACATTGCTGAGCCTAACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTT
AAGGACAAGACCAGCGGCTAATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGA
GAAGGAGAGGAACACAGCAGCCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAG
ACCAGCATGTCTTCAGTAGCCAAACTACTTCTTGAGCATAGATAGGTATAGTGGGTTTGCTTGAGGTGGTAAGGCTTTGCTGGACCCTGT
TGCAGGCAAAAGGAGTAATTGATTTAAAGTACTGTTAATGATGATAATGATTTTTTTTTTAAACTCATATATTGGGATTTTCACCAAAAT
AATGCTTTTGAAAAAAAGAAAAAAAAAACGGATATATTGAGAATCAAAGTAGAAGTTTTAGGAATGCAAAATAAGTCATCTTGCATACAG
GGAGTGGTTAAGTAAGGTTTCATCACCCCTTTAGCACTGCTTTTCTGAAGACTTCAGTTTTGTTAAGGAGATTTAGTTTTACTGCTTTGA
CTGGTGGGTCTCTAGAAGCAAAACTGAGTGATAACTCATGAGAAGTACTGATAGGACCTTTATCTGGATATGGTCCTATAGGTTATTCTG

>In-frame_ENST00000444882_ENST00000537197_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=304_stop in transcript=1152
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

--------------------------------------------------------------
>In-frame_ENST00000356847_ENST00000300738_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1641nt_BP=461nt
GCAAGCGCCCTTGGCGCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGCCAGTG
GCACCCGGAAGAAAGAGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAGACGGC
GAGGCCCGGCCCCCGCTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTTTCGTT
GACACTCAGGACCGTACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGG
CTCCTGCTCAGGCGTCCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACAC
CCAATAGAGAGATTCTTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGCAAAGT
ATGGTATAAGAAACAGTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACCTTACA
CCAGCAACATCTATACTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGGCCTAT
GGCATGAAGAGATGAAAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACTTTATA
AAACTGTGTGGGAAATCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAACATCC
ACATTGCTGAGCCTAACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTTAAGGA
CAAGACCAGCGGCTAATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGAGAAGG
AGAGGAACACAGCAGCCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAGACCAG
CATGTCTTCAGTAGCCAAACTACTTCTTGAGCATAGATAGGTATAGTGGGTTTGCTTGAGGTGGTAAGGCTTTGCTGGACCCTGTTGCAG
GCAAAAGGAGTAATTGATTTAAAGTACTGTTAATGATGATAATGATTTTTTTTTTAAACTCATATATTGGGATTTTCACCAAAATAATGC
TTTTGAAAAAAAGAAAAAAAAAACGGATATATTGAGAATCAAAGTAGAAGTTTTAGGAATGCAAAATAAGTCATCTTGCATACAGGGAGT
GGTTAAGTAAGGTTTCATCACCCCTTTAGCACTGCTTTTCTGAAGACTTCAGTTTTGTTAAGGAGATTTAGTTTTACTGCTTTGACTGGT
GGGTCTCTAGAAGCAAAACTGAGTGATAACTCATGAGAAGTACTGATAGGACCTTTATCTGGATATGGTCCTATAGGTTATTCTGAAATA

>In-frame_ENST00000356847_ENST00000300738_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=299_stop in transcript=1147
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

--------------------------------------------------------------
>In-frame_ENST00000356847_ENST00000423050_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1640nt_BP=461nt
GCAAGCGCCCTTGGCGCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGCCAGTG
GCACCCGGAAGAAAGAGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAGACGGC
GAGGCCCGGCCCCCGCTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTTTCGTT
GACACTCAGGACCGTACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGG
CTCCTGCTCAGGCGTCCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACAC
CCAATAGAGAGATTCTTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGCAAAGT
ATGGTATAAGAAACAGTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACCTTACA
CCAGCAACATCTATACTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGGCCTAT
GGCATGAAGAGATGAAAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACTTTATA
AAACTGTGTGGGAAATCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAACATCC
ACATTGCTGAGCCTAACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTTAAGGA
CAAGACCAGCGGCTAATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGAGAAGG
AGAGGAACACAGCAGCCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAGACCAG
CATGTCTTCAGTAGCCAAACTACTTCTTGAGCATAGATAGGTATAGTGGGTTTGCTTGAGGTGGTAAGGCTTTGCTGGACCCTGTTGCAG
GCAAAAGGAGTAATTGATTTAAAGTACTGTTAATGATGATAATGATTTTTTTTTTAAACTCATATATTGGGATTTTCACCAAAATAATGC
TTTTGAAAAAAAGAAAAAAAAAACGGATATATTGAGAATCAAAGTAGAAGTTTTAGGAATGCAAAATAAGTCATCTTGCATACAGGGAGT
GGTTAAGTAAGGTTTCATCACCCCTTTAGCACTGCTTTTCTGAAGACTTCAGTTTTGTTAAGGAGATTTAGTTTTACTGCTTTGACTGGT
GGGTCTCTAGAAGCAAAACTGAGTGATAACTCATGAGAAGTACTGATAGGACCTTTATCTGGATATGGTCCTATAGGTTATTCTGAAATA

>In-frame_ENST00000356847_ENST00000423050_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=299_stop in transcript=1147
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

--------------------------------------------------------------
>In-frame_ENST00000356847_ENST00000534285_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1211nt_BP=461nt
GCAAGCGCCCTTGGCGCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGCCAGTG
GCACCCGGAAGAAAGAGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAGACGGC
GAGGCCCGGCCCCCGCTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTTTCGTT
GACACTCAGGACCGTACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGG
CTCCTGCTCAGGCGTCCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACAC
CCAATAGAGAGATTCTTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGCAAAGT
ATGGTATAAGAAACAGTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACCTTACA
CCAGCAACATCTATACTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGGCCTAT
GGCATGAAGAGATGAAAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACTTTATA
AAACTGTGTGGGAAATCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAACATCC
ACATTGCTGAGCCTAACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTTAAGGA
CAAGACCAGCGGCTAATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGAGAAGG
AGAGGAACACAGCAGCCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAGACCAG

>In-frame_ENST00000356847_ENST00000534285_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=299_stop in transcript=1147
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

--------------------------------------------------------------
>In-frame_ENST00000356847_ENST00000537197_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(transcript)=1640nt_BP=461nt
GCAAGCGCCCTTGGCGCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGCCAGTG
GCACCCGGAAGAAAGAGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAGACGGC
GAGGCCCGGCCCCCGCTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTTTCGTT
GACACTCAGGACCGTACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGG
CTCCTGCTCAGGCGTCCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACAC
CCAATAGAGAGATTCTTCAGTATGATATGTGGAATGTTACTCCTACAGACCTATGGGACTGGAAGGTTCTCAAGGAGAAGATTGCAAAGT
ATGGTATAAGAAACAGTTTACTTATTGCCCCGATGCCTACAGCTTCCACTGCTCAGATCCTGGGGAATAATGAGTCCATTGAACCTTACA
CCAGCAACATCTATACTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTATTGAAAGATCTTACCGAGCGGGGCCTAT
GGCATGAAGAGATGAAAAACCAGATTATTGCATGCAATGGCTCTATTCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAACTTTATA
AAACTGTGTGGGAAATCTCTCAGAAAACTGTTCTCAAGATGGCAGCTGAGAGAGGTGCTTTCATTGATCAAAGCCAATCTTTGAACATCC
ACATTGCTGAGCCTAACTATGGCAAACTCACTAGTATGCACTTCTACGGCTGGAAGCAGGGTTTGAAGACTGGGATGTATTATTTAAGGA
CAAGACCAGCGGCTAATCCAATCCAGTTCACTCTAAATAAGGAGAAGCTAAAAGATAAAGAAAAGGTATCAAAAGAGGAAGAAGAGAAGG
AGAGGAACACAGCAGCCATGGTGTGCTCTTTGGAGAATAGAGATGAATGTCTGATGTGTGGATCCTGAGGAAAGACTTGGAAGAGACCAG
CATGTCTTCAGTAGCCAAACTACTTCTTGAGCATAGATAGGTATAGTGGGTTTGCTTGAGGTGGTAAGGCTTTGCTGGACCCTGTTGCAG
GCAAAAGGAGTAATTGATTTAAAGTACTGTTAATGATGATAATGATTTTTTTTTTAAACTCATATATTGGGATTTTCACCAAAATAATGC
TTTTGAAAAAAAGAAAAAAAAAACGGATATATTGAGAATCAAAGTAGAAGTTTTAGGAATGCAAAATAAGTCATCTTGCATACAGGGAGT
GGTTAAGTAAGGTTTCATCACCCCTTTAGCACTGCTTTTCTGAAGACTTCAGTTTTGTTAAGGAGATTTAGTTTTACTGCTTTGACTGGT
GGGTCTCTAGAAGCAAAACTGAGTGATAACTCATGAGAAGTACTGATAGGACCTTTATCTGGATATGGTCCTATAGGTTATTCTGAAATA

>In-frame_ENST00000356847_ENST00000537197_TCGA-G2-AA3F-01A_GOLGA4_chr3_37292975_+_RRM1_chr11_4150304_length(amino acids)=282AA_start in transcript=299_stop in transcript=1147
MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNREILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKT
VLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS

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Fusion Gene PPI Analysis for GOLGA4-RRM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneGOLGA4chr3:37292975chr11:4150304ENST00000356847+223133_20354.02244.0MACF1
HgeneGOLGA4chr3:37292975chr11:4150304ENST00000361924+224133_20354.02306.3333333333335MACF1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GOLGA4-RRM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GOLGA4-RRM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneGOLGA4C0033578Prostatic Neoplasms1CTD_human
HgeneGOLGA4C0037274Dermatologic disorders1CTD_human
HgeneGOLGA4C0274861Arsenic Poisoning, Inorganic1CTD_human
HgeneGOLGA4C0274862Nervous System, Organic Arsenic Poisoning1CTD_human
HgeneGOLGA4C0311375Arsenic Poisoning1CTD_human
HgeneGOLGA4C0376358Malignant neoplasm of prostate1CTD_human
HgeneGOLGA4C0751851Arsenic Encephalopathy1CTD_human
HgeneGOLGA4C0751852Arsenic Induced Polyneuropathy1CTD_human
TgeneRRM1C0007131Non-Small Cell Lung Carcinoma1CTD_human
TgeneRRM1C0011999Diastematomyelia1CTD_human
TgeneRRM1C0027794Neural Tube Defects1CTD_human
TgeneRRM1C0027806Neurenteric Cyst1CTD_human
TgeneRRM1C0080218Tethered Cord Syndrome1CTD_human
TgeneRRM1C0152013Adenocarcinoma of lung (disorder)1CTD_human
TgeneRRM1C0152234Iniencephaly1CTD_human
TgeneRRM1C0152426Craniorachischisis1CTD_human
TgeneRRM1C0206686Adrenocortical carcinoma1CTD_human
TgeneRRM1C0235874Disease Exacerbation1CTD_human
TgeneRRM1C0266453Exencephaly1CTD_human
TgeneRRM1C0344479Spinal Cord Myelodysplasia1CTD_human
TgeneRRM1C0702169Acrania1CTD_human
TgeneRRM1C2239176Liver carcinoma1CTD_human