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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GOSR1-AP2B1 (FusionGDB2 ID:33907)

Fusion Gene Summary for GOSR1-AP2B1

check button Fusion gene summary
Fusion gene informationFusion gene name: GOSR1-AP2B1
Fusion gene ID: 33907
HgeneTgene
Gene symbol

GOSR1

AP2B1

Gene ID

9527

163

Gene namegolgi SNAP receptor complex member 1adaptor related protein complex 2 subunit beta 1
SynonymsGOLIM2|GOS-28|GOS28|GOS28/P28|GS28|P28ADTB2|AP105B|AP2-BETA|CLAPB1
Cytomap

17q11.2

17q12

Type of geneprotein-codingprotein-coding
DescriptionGolgi SNAP receptor complex member 128 kDa Golgi SNARE protein28 kDa cis-Golgi SNARE p28Golgi SNARE 28 kDacis-golgi SNAREgolgi integral membrane protein 2AP-2 complex subunit betaadapter-related protein complex 2 beta subunitadapter-related protein complex 2 subunit betaadaptin, beta 2 (beta)adaptor protein complex AP-2 subunit betaadaptor related protein complex 2 beta 1 subunitadaptor-related prote
Modification date2020031320200327
UniProtAcc

O95249

P63010

Ensembl transtripts involved in fusion geneENST00000225724, ENST00000451249, 
ENST00000467337, ENST00000581721, 
ENST00000579905, 		ENST00000262325, 
ENST00000592545, ENST00000538556, 
ENST00000312678, ENST00000589344, 
ENST00000537622, ENST00000545922, 
Fusion gene scores* DoF score9 X 5 X 8=36014 X 18 X 9=2268
# samples 1019
** MAII scorelog2(10/360*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/2268*10)=-3.57734931661128
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GOSR1 [Title/Abstract] AND AP2B1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGOSR1(28819771)-AP2B1(34009714), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGOSR1

GO:0042147

retrograde transport, endosome to Golgi

15215310

TgeneAP2B1

GO:0072583

clathrin-dependent endocytosis

23676497


check buttonFusion gene breakpoints across GOSR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across AP2B1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-55-6971-01AGOSR1chr17

28819771

+AP2B1chr17

34009714

+
ChimerDB4LUADTCGA-55-6971-01AGOSR1chr17

28819771

+AP2B1chr17

34009714

+
ChimerDB4LUADTCGA-55-6971-01AGOSR1chr17

28819771

-AP2B1chr17

34009714

+


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Fusion Gene ORF analysis for GOSR1-AP2B1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000225724ENST00000262325GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000225724ENST00000592545GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000225724ENST00000538556GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000225724ENST00000312678GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000225724ENST00000589344GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000225724ENST00000537622GOSR1chr17

28819771

+AP2B1chr17

34009714

+
5CDS-3UTRENST00000225724ENST00000545922GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000451249ENST00000262325GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000451249ENST00000592545GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000451249ENST00000538556GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000451249ENST00000312678GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000451249ENST00000589344GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000451249ENST00000537622GOSR1chr17

28819771

+AP2B1chr17

34009714

+
5CDS-3UTRENST00000451249ENST00000545922GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000467337ENST00000262325GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000467337ENST00000592545GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000467337ENST00000538556GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000467337ENST00000312678GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000467337ENST00000589344GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000467337ENST00000537622GOSR1chr17

28819771

+AP2B1chr17

34009714

+
5CDS-3UTRENST00000467337ENST00000545922GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000581721ENST00000262325GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000581721ENST00000592545GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000581721ENST00000538556GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000581721ENST00000312678GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000581721ENST00000589344GOSR1chr17

28819771

+AP2B1chr17

34009714

+
In-frameENST00000581721ENST00000537622GOSR1chr17

28819771

+AP2B1chr17

34009714

+
5CDS-3UTRENST00000581721ENST00000545922GOSR1chr17

28819771

+AP2B1chr17

34009714

+
intron-3CDSENST00000579905ENST00000262325GOSR1chr17

28819771

+AP2B1chr17

34009714

+
intron-3CDSENST00000579905ENST00000592545GOSR1chr17

28819771

+AP2B1chr17

34009714

+
intron-3CDSENST00000579905ENST00000538556GOSR1chr17

28819771

+AP2B1chr17

34009714

+
intron-3CDSENST00000579905ENST00000312678GOSR1chr17

28819771

+AP2B1chr17

34009714

+
intron-3CDSENST00000579905ENST00000589344GOSR1chr17

28819771

+AP2B1chr17

34009714

+
intron-3CDSENST00000579905ENST00000537622GOSR1chr17

28819771

+AP2B1chr17

34009714

+
intron-3UTRENST00000579905ENST00000545922GOSR1chr17

28819771

+AP2B1chr17

34009714

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000225724GOSR1chr1728819771+ENST00000262325AP2B1chr1734009714+3837587721118348
ENST00000225724GOSR1chr1728819771+ENST00000592545AP2B1chr1734009714+1506587721118348
ENST00000225724GOSR1chr1728819771+ENST00000538556AP2B1chr1734009714+1506587721118348
ENST00000225724GOSR1chr1728819771+ENST00000312678AP2B1chr1734009714+1795587721118348
ENST00000225724GOSR1chr1728819771+ENST00000589344AP2B1chr1734009714+1185587721118348
ENST00000225724GOSR1chr1728819771+ENST00000537622AP2B1chr1734009714+1509587721118348
ENST00000451249GOSR1chr1728819771+ENST00000262325AP2B1chr1734009714+3816566571097346
ENST00000451249GOSR1chr1728819771+ENST00000592545AP2B1chr1734009714+1485566571097346
ENST00000451249GOSR1chr1728819771+ENST00000538556AP2B1chr1734009714+1485566571097346
ENST00000451249GOSR1chr1728819771+ENST00000312678AP2B1chr1734009714+1774566571097346
ENST00000451249GOSR1chr1728819771+ENST00000589344AP2B1chr1734009714+1164566571097346
ENST00000451249GOSR1chr1728819771+ENST00000537622AP2B1chr1734009714+1488566571097346
ENST00000467337GOSR1chr1728819771+ENST00000262325AP2B1chr1734009714+3792542871073328
ENST00000467337GOSR1chr1728819771+ENST00000592545AP2B1chr1734009714+1461542871073328
ENST00000467337GOSR1chr1728819771+ENST00000538556AP2B1chr1734009714+1461542871073328
ENST00000467337GOSR1chr1728819771+ENST00000312678AP2B1chr1734009714+1750542871073328
ENST00000467337GOSR1chr1728819771+ENST00000589344AP2B1chr1734009714+1140542871073328
ENST00000467337GOSR1chr1728819771+ENST00000537622AP2B1chr1734009714+1464542871073328
ENST00000581721GOSR1chr1728819771+ENST00000262325AP2B1chr1734009714+376051071041344
ENST00000581721GOSR1chr1728819771+ENST00000592545AP2B1chr1734009714+142951071041344
ENST00000581721GOSR1chr1728819771+ENST00000538556AP2B1chr1734009714+142951071041344
ENST00000581721GOSR1chr1728819771+ENST00000312678AP2B1chr1734009714+171851071041344
ENST00000581721GOSR1chr1728819771+ENST00000589344AP2B1chr1734009714+110851071041344
ENST00000581721GOSR1chr1728819771+ENST00000537622AP2B1chr1734009714+143251071041344

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000225724ENST00000262325GOSR1chr1728819771+AP2B1chr1734009714+0.0005265980.9994734
ENST00000225724ENST00000592545GOSR1chr1728819771+AP2B1chr1734009714+0.000502750.9994973
ENST00000225724ENST00000538556GOSR1chr1728819771+AP2B1chr1734009714+0.000502750.9994973
ENST00000225724ENST00000312678GOSR1chr1728819771+AP2B1chr1734009714+0.0003984930.99960154
ENST00000225724ENST00000589344GOSR1chr1728819771+AP2B1chr1734009714+0.0005329580.9994671
ENST00000225724ENST00000537622GOSR1chr1728819771+AP2B1chr1734009714+0.0005057420.9994942
ENST00000451249ENST00000262325GOSR1chr1728819771+AP2B1chr1734009714+0.0008644160.99913555
ENST00000451249ENST00000592545GOSR1chr1728819771+AP2B1chr1734009714+0.000862950.9991371
ENST00000451249ENST00000538556GOSR1chr1728819771+AP2B1chr1734009714+0.000862950.9991371
ENST00000451249ENST00000312678GOSR1chr1728819771+AP2B1chr1734009714+0.0006958620.9993042
ENST00000451249ENST00000589344GOSR1chr1728819771+AP2B1chr1734009714+0.0008857160.9991142
ENST00000451249ENST00000537622GOSR1chr1728819771+AP2B1chr1734009714+0.00086010.9991399
ENST00000467337ENST00000262325GOSR1chr1728819771+AP2B1chr1734009714+0.0008935720.99910635
ENST00000467337ENST00000592545GOSR1chr1728819771+AP2B1chr1734009714+0.0009374780.9990625
ENST00000467337ENST00000538556GOSR1chr1728819771+AP2B1chr1734009714+0.0009374780.9990625
ENST00000467337ENST00000312678GOSR1chr1728819771+AP2B1chr1734009714+0.0007614190.9992386
ENST00000467337ENST00000589344GOSR1chr1728819771+AP2B1chr1734009714+0.0011542080.9988458
ENST00000467337ENST00000537622GOSR1chr1728819771+AP2B1chr1734009714+0.0009485410.9990515
ENST00000581721ENST00000262325GOSR1chr1728819771+AP2B1chr1734009714+0.000644450.9993555
ENST00000581721ENST00000592545GOSR1chr1728819771+AP2B1chr1734009714+0.0008306250.99916935
ENST00000581721ENST00000538556GOSR1chr1728819771+AP2B1chr1734009714+0.0008306250.99916935
ENST00000581721ENST00000312678GOSR1chr1728819771+AP2B1chr1734009714+0.0005874750.99941254
ENST00000581721ENST00000589344GOSR1chr1728819771+AP2B1chr1734009714+0.0010215540.9989785
ENST00000581721ENST00000537622GOSR1chr1728819771+AP2B1chr1734009714+0.0008392550.99916077

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Fusion Genomic Features for GOSR1-AP2B1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
GOSR1chr1728819771+AP2B1chr1734009713+3.38E-091
GOSR1chr1728819771+AP2B1chr1734009713+3.38E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GOSR1-AP2B1


check button Go to

FGviewer for the breakpoints of chr17:28819771-chr17:34009714

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GOSR1

O95249

AP2B1

P63010

FUNCTION: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi. {ECO:0000269|PubMed:15215310, ECO:0000269|PubMed:21860593}.FUNCTION: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. During long-term potentiation in hippocampal neurons, AP-2 is responsible for the endocytosis of ADAM10 (PubMed:23676497). The AP-2 beta subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins; at least some clathrin-associated sorting proteins (CLASPs) are recognized by their [DE]-X(1,2)-F-X-X-[FL]-X-X-X-R motif. The AP-2 beta subunit binds to clathrin heavy chain, promoting clathrin lattice assembly; clathrin displaces at least some CLASPs from AP2B1 which probably then can be positioned for further coat assembly. {ECO:0000269|PubMed:14745134, ECO:0000269|PubMed:14985334, ECO:0000269|PubMed:15473838, ECO:0000269|PubMed:19033387, ECO:0000269|PubMed:23676497}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGOSR1chr17:28819771chr17:34009714ENST00000225724+6968_95171.66666666666666251.0Coiled coilOntology_term=ECO:0000255
HgeneGOSR1chr17:28819771chr17:34009714ENST00000225724+699_30171.66666666666666251.0Coiled coilOntology_term=ECO:0000255
HgeneGOSR1chr17:28819771chr17:34009714ENST00000467337+6968_95106.66666666666667186.0Coiled coilOntology_term=ECO:0000255
HgeneGOSR1chr17:28819771chr17:34009714ENST00000467337+699_30106.66666666666667186.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGOSR1chr17:28819771chr17:34009714ENST00000225724+692_229171.66666666666666251.0Topological domainCytoplasmic
HgeneGOSR1chr17:28819771chr17:34009714ENST00000467337+692_229106.66666666666667186.0Topological domainCytoplasmic
HgeneGOSR1chr17:28819771chr17:34009714ENST00000225724+69230_250171.66666666666666251.0TransmembraneHelical%3B Anchor for type IV membrane protein
HgeneGOSR1chr17:28819771chr17:34009714ENST00000467337+69230_250106.66666666666667186.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneAP2B1chr17:28819771chr17:34009714ENST000002623251521576_716760.6666666666666938.0Compositional biasNote=Pro-rich (stalk region)
TgeneAP2B1chr17:28819771chr17:34009714ENST000003126781622576_716774.6666666666666952.0Compositional biasNote=Pro-rich (stalk region)
TgeneAP2B1chr17:28819771chr17:34009714ENST000005376221622576_716774.6666666666666952.0Compositional biasNote=Pro-rich (stalk region)
TgeneAP2B1chr17:28819771chr17:34009714ENST000005385561622576_716703.6666666666666881.0Compositional biasNote=Pro-rich (stalk region)
TgeneAP2B1chr17:28819771chr17:34009714ENST000005893441622576_716774.6666666666666952.0Compositional biasNote=Pro-rich (stalk region)


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Fusion Gene Sequence for GOSR1-AP2B1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000225724_ENST00000262325_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=3837nt_BP=587nt
ACACGCACCATGGTGACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGC
AGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGT
TACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATG
TTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGT
GTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAA
GCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAAC
AACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCA
CTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTG
GCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAG
GTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCC
AGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAAT
GGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAA
TACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGA
ACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAA
CATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTG
CTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTG
TAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTAT
ACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGA
GATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCT
TTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCATATTATAATCTCATTTGATTGCTCTGCAGTTGG
GAACGGTGATCTTCTTGAATGATGTTTCAGTGTGCAAAAACTATAGAGCCTGTCAGCACCAAAGCTGACAGAAGTTATACCTTACTCCTT
TCCTTTCCCCTGAACAAACCTGCTAATCCCACTAATTCAGGAATTTGAGTAGAGATGGGGAACAAGAACCCAGATGCTGTCCCCTCACCC
CCTCTCCTGTATTTCTCAGGTCCAGTTCAAATCTAAAATTCTACTTTTAGAGTTGAAACAGAGTAATAACTTATCTAACCCTCTTTTCCT
ACAAAGGAGAAAGATAAAAGGCACAAAGGTTACCGCCAAGGCCCGTCAGCTGTGTAGTGGCAAAGCCGAGACCGAGTCTCCTAAGTCCCC
GTCAGTGTGGTTTTCACCACAGGACTGTCTCTTGTCGTTTTCCCCTAATGCCTTCTCCTGCCTTTTCTGTGCCTAGTTTTTGGCTCTTCA
CATATTCCATATTGATTTTGACGCTCTGTATATTGGCATCAGGTGGCAGCTGAATATCTTTTGAATTACTCGAAGGTAAAGCCAGATGCC
AGAATGAAGGTGTAGCCAGTGTTTCCCATATGCCCCTGGAGCCCCACTTATTGAGGCCAGCAGAATAGGTGCAGAGATGAAGTGAGCTTA
GAGATGTTGCAAATGCTCTTTATCCCTTCAGCTCTCTGATCTGCTCTTTCTTCATGATACTTAGTCTGCAGGGCATATTAAGATCATCCC
AGAGGTTCAGGCAGTTCCTGTCATCTCTGAAAAGACTGGGGGATATGAAATCTTCCCCCTACCCCACTTAATGCGTTGGATATGATTTTT
CAAAGAATGCTTCATGCCCAAAATACCAGCCTGTTTAGCAGTGTTACACTGTTTGATCTGCGGGCACTTGTTGCATTGCCTGGCACCCAA
TATTCAGGGTCCATGACTAAGACTGGTCTTCTCAGATGCCCTGCTTAAATCAGGGGCACTTCAGGCTCCACAGGCGTCATGTTGGACTGA
GACCTAACTCACTGGACTCAGAGGAGGAATCGTGGAAAACAAGAGCAAAACTACCCCACACCCCTATTTCATGTCTGAAATAACCCTGTT
TCATACCAGTTGCAAAGCTTGTGGGGAGCGGTCCCACAAAGCACTTTCTTAAACCTTGAGAATCTCCAAGAGAAAAATATTTGGGGAAGG
AGGGAGGAAATATGTCCCTTGCACACCACCCCTGAAGCACATGGCAGTAGGAAACAGCATAGGATTGTATGTGGGAGGTGGATAGGTCGG
TGATGTGTGGAGCGGAAAAGCAGGTTGGTAAAGTTCCCTTCTTGGGACTTATTCCTGGAGTCAGTGGATACAAGTAGTGCAGAAGGTTCA
CACTGCAAATAGTGTTCTCATCTCAAAGCAAACTATCATTCCAGAAGGAAAAGTGTGTCAGGGCAAGCAGACAACACAATTTCCTATCAG
AATATGTCCCTCAACCCCCGAAACAAGGCTTCTCTCAGCCTCCCCACCAGTGATGGATAACAGCTCCTATTCTCAGCTGACCTGACTGAG
CCAACCCATGAACTCTTCACTCCTTGGGGAAGCCACCTCCCATCACACCCCTGAGCAGAGTTAGGGAGGAATTCTACTTCCCATAAAAGG
ACCTCTCCTGAGAGGCAAAACCTGTTGCCTCCACCACGGCTTCCCTCTTGGCTCATTCCAAGCTTGGCCAAATTGGGGAAGTGGGATGGA
GGTTGCCCTGCATCCCCCCTCCTCTGCCTGAGTGTGTCTTTGTAATGTCAGCTGGCATCATACAAAGAGCAGGAGAAGCAAACACCCAGA
ACTCTTTTGCTGGTCAGAGATTCCCTGAGTGTCTGTCCTCACCCAAGCCTGCTCTGTGTCTGTGTTGTGAAGCTTGAGACTCTGGAAAGA
AATGGGGAGGGGGGGCAGGGGAAATGTTGCCCTAAGAATGCTTCTCATTCCTCTGTTCTTATTGGGTCCTGTTTTTCGGGAGGGTGGGGG

>In-frame_ENST00000225724_ENST00000262325_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=348AA_start in transcript=72_stop in transcript=1118
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTP
LAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHL

--------------------------------------------------------------
>In-frame_ENST00000225724_ENST00000592545_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1506nt_BP=587nt
ACACGCACCATGGTGACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGC
AGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGT
TACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATG
TTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGT
GTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAA
GCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAAC
AACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCA
CTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTG
GCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAG
GTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCC
AGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAAT
GGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAA
TACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGA
ACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAA
CATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTG
CTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTG

>In-frame_ENST00000225724_ENST00000592545_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=348AA_start in transcript=72_stop in transcript=1118
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTP
LAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHL

--------------------------------------------------------------
>In-frame_ENST00000225724_ENST00000538556_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1506nt_BP=587nt
ACACGCACCATGGTGACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGC
AGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGT
TACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATG
TTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGT
GTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAA
GCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAAC
AACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCA
CTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTG
GCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAG
GTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCC
AGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAAT
GGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAA
TACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGA
ACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAA
CATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTG
CTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTG

>In-frame_ENST00000225724_ENST00000538556_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=348AA_start in transcript=72_stop in transcript=1118
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTP
LAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHL

--------------------------------------------------------------
>In-frame_ENST00000225724_ENST00000312678_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1795nt_BP=587nt
ACACGCACCATGGTGACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGC
AGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGT
TACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATG
TTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGT
GTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAA
GCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAAC
AACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCA
CTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTG
GCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAG
GTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCC
AGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAAT
GGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAA
TACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGA
ACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAA
CATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTG
CTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTG
TAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTAT
ACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGA
GATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCT

>In-frame_ENST00000225724_ENST00000312678_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=348AA_start in transcript=72_stop in transcript=1118
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTP
LAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHL

--------------------------------------------------------------
>In-frame_ENST00000225724_ENST00000589344_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1185nt_BP=587nt
ACACGCACCATGGTGACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGC
AGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGT
TACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATG
TTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGT
GTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAA
GCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAAC
AACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCA
CTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTG
GCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAG
GTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCC
AGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAAT
GGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAA
TACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGA

>In-frame_ENST00000225724_ENST00000589344_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=348AA_start in transcript=72_stop in transcript=1118
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTP
LAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHL

--------------------------------------------------------------
>In-frame_ENST00000225724_ENST00000537622_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1509nt_BP=587nt
ACACGCACCATGGTGACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGC
AGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGT
TACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATG
TTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGT
GTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAA
GCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAAC
AACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCA
CTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTG
GCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAG
GTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCC
AGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAAT
GGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAA
TACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGA
ACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAA
CATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTG
CTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTG

>In-frame_ENST00000225724_ENST00000537622_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=348AA_start in transcript=72_stop in transcript=1118
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTP
LAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHL

--------------------------------------------------------------
>In-frame_ENST00000451249_ENST00000262325_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=3816nt_BP=566nt
ACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGAT
CTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGT
ACCCGAGATGGAAGACGCGACAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAG
ATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCC
CTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGG
GAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTT
TTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATT
GATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGAT
GTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAG
GATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAAT
GTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAA
CTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGAC
AGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTG
TATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGG
ATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGT
GGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAA
AGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTATACTTTTGTACATATGAGAAAT
CAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGAGATGCAGTTACCTACCCTAGC
TTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCT
TTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCATATTATAATCTCATTTGATTGCTCTGCAGTTGGGAACGGTGATCTTCTTGAATG
ATGTTTCAGTGTGCAAAAACTATAGAGCCTGTCAGCACCAAAGCTGACAGAAGTTATACCTTACTCCTTTCCTTTCCCCTGAACAAACCT
GCTAATCCCACTAATTCAGGAATTTGAGTAGAGATGGGGAACAAGAACCCAGATGCTGTCCCCTCACCCCCTCTCCTGTATTTCTCAGGT
CCAGTTCAAATCTAAAATTCTACTTTTAGAGTTGAAACAGAGTAATAACTTATCTAACCCTCTTTTCCTACAAAGGAGAAAGATAAAAGG
CACAAAGGTTACCGCCAAGGCCCGTCAGCTGTGTAGTGGCAAAGCCGAGACCGAGTCTCCTAAGTCCCCGTCAGTGTGGTTTTCACCACA
GGACTGTCTCTTGTCGTTTTCCCCTAATGCCTTCTCCTGCCTTTTCTGTGCCTAGTTTTTGGCTCTTCACATATTCCATATTGATTTTGA
CGCTCTGTATATTGGCATCAGGTGGCAGCTGAATATCTTTTGAATTACTCGAAGGTAAAGCCAGATGCCAGAATGAAGGTGTAGCCAGTG
TTTCCCATATGCCCCTGGAGCCCCACTTATTGAGGCCAGCAGAATAGGTGCAGAGATGAAGTGAGCTTAGAGATGTTGCAAATGCTCTTT
ATCCCTTCAGCTCTCTGATCTGCTCTTTCTTCATGATACTTAGTCTGCAGGGCATATTAAGATCATCCCAGAGGTTCAGGCAGTTCCTGT
CATCTCTGAAAAGACTGGGGGATATGAAATCTTCCCCCTACCCCACTTAATGCGTTGGATATGATTTTTCAAAGAATGCTTCATGCCCAA
AATACCAGCCTGTTTAGCAGTGTTACACTGTTTGATCTGCGGGCACTTGTTGCATTGCCTGGCACCCAATATTCAGGGTCCATGACTAAG
ACTGGTCTTCTCAGATGCCCTGCTTAAATCAGGGGCACTTCAGGCTCCACAGGCGTCATGTTGGACTGAGACCTAACTCACTGGACTCAG
AGGAGGAATCGTGGAAAACAAGAGCAAAACTACCCCACACCCCTATTTCATGTCTGAAATAACCCTGTTTCATACCAGTTGCAAAGCTTG
TGGGGAGCGGTCCCACAAAGCACTTTCTTAAACCTTGAGAATCTCCAAGAGAAAAATATTTGGGGAAGGAGGGAGGAAATATGTCCCTTG
CACACCACCCCTGAAGCACATGGCAGTAGGAAACAGCATAGGATTGTATGTGGGAGGTGGATAGGTCGGTGATGTGTGGAGCGGAAAAGC
AGGTTGGTAAAGTTCCCTTCTTGGGACTTATTCCTGGAGTCAGTGGATACAAGTAGTGCAGAAGGTTCACACTGCAAATAGTGTTCTCAT
CTCAAAGCAAACTATCATTCCAGAAGGAAAAGTGTGTCAGGGCAAGCAGACAACACAATTTCCTATCAGAATATGTCCCTCAACCCCCGA
AACAAGGCTTCTCTCAGCCTCCCCACCAGTGATGGATAACAGCTCCTATTCTCAGCTGACCTGACTGAGCCAACCCATGAACTCTTCACT
CCTTGGGGAAGCCACCTCCCATCACACCCCTGAGCAGAGTTAGGGAGGAATTCTACTTCCCATAAAAGGACCTCTCCTGAGAGGCAAAAC
CTGTTGCCTCCACCACGGCTTCCCTCTTGGCTCATTCCAAGCTTGGCCAAATTGGGGAAGTGGGATGGAGGTTGCCCTGCATCCCCCCTC
CTCTGCCTGAGTGTGTCTTTGTAATGTCAGCTGGCATCATACAAAGAGCAGGAGAAGCAAACACCCAGAACTCTTTTGCTGGTCAGAGAT
TCCCTGAGTGTCTGTCCTCACCCAAGCCTGCTCTGTGTCTGTGTTGTGAAGCTTGAGACTCTGGAAAGAAATGGGGAGGGGGGGCAGGGG
AAATGTTGCCCTAAGAATGCTTCTCATTCCTCTGTTCTTATTGGGTCCTGTTTTTCGGGAGGGTGGGGGTTGGGGGAAGCTTGACCTTGT

>In-frame_ENST00000451249_ENST00000262325_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=346AA_start in transcript=57_stop in transcript=1097
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYT
NSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLA
IHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNA

--------------------------------------------------------------
>In-frame_ENST00000451249_ENST00000592545_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1485nt_BP=566nt
ACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGAT
CTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGT
ACCCGAGATGGAAGACGCGACAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAG
ATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCC
CTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGG
GAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTT
TTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATT
GATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGAT
GTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAG
GATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAAT
GTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAA
CTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGAC
AGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTG
TATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGG
ATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGT
GGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAA

>In-frame_ENST00000451249_ENST00000592545_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=346AA_start in transcript=57_stop in transcript=1097
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYT
NSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLA
IHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNA

--------------------------------------------------------------
>In-frame_ENST00000451249_ENST00000538556_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1485nt_BP=566nt
ACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGAT
CTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGT
ACCCGAGATGGAAGACGCGACAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAG
ATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCC
CTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGG
GAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTT
TTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATT
GATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGAT
GTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAG
GATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAAT
GTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAA
CTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGAC
AGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTG
TATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGG
ATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGT
GGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAA

>In-frame_ENST00000451249_ENST00000538556_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=346AA_start in transcript=57_stop in transcript=1097
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYT
NSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLA
IHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNA

--------------------------------------------------------------
>In-frame_ENST00000451249_ENST00000312678_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1774nt_BP=566nt
ACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGAT
CTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGT
ACCCGAGATGGAAGACGCGACAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAG
ATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCC
CTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGG
GAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTT
TTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATT
GATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGAT
GTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAG
GATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAAT
GTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAA
CTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGAC
AGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTG
TATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGG
ATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGT
GGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAA
AGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTATACTTTTGTACATATGAGAAAT
CAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGAGATGCAGTTACCTACCCTAGC
TTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCT

>In-frame_ENST00000451249_ENST00000312678_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=346AA_start in transcript=57_stop in transcript=1097
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYT
NSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLA
IHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNA

--------------------------------------------------------------
>In-frame_ENST00000451249_ENST00000589344_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1164nt_BP=566nt
ACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGAT
CTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGT
ACCCGAGATGGAAGACGCGACAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAG
ATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCC
CTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGG
GAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTT
TTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATT
GATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGAT
GTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAG
GATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAAT
GTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAA
CTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGAC

>In-frame_ENST00000451249_ENST00000589344_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=346AA_start in transcript=57_stop in transcript=1097
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYT
NSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLA
IHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNA

--------------------------------------------------------------
>In-frame_ENST00000451249_ENST00000537622_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1488nt_BP=566nt
ACTTTCCGGCCTGCATCGCCTCTGCTCCCCTATCCCGGCTGACGTTGGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGAT
CTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGT
ACCCGAGATGGAAGACGCGACAGTTCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAG
ATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCC
CTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGG
GAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTT
TTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATT
GATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGAT
GTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAG
GATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAAT
GTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAA
CTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGAC
AGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTG
TATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGG
ATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGT
GGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAA

>In-frame_ENST00000451249_ENST00000537622_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=346AA_start in transcript=57_stop in transcript=1097
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYT
NSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLA
IHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNA

--------------------------------------------------------------
>In-frame_ENST00000467337_ENST00000262325_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=3792nt_BP=542nt
GGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGGTGAGGGCGAGAAGGCCTCCGGATCTCAGGAAACAGGCTCGACAGCTG
GAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGT
TCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTT
ACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCAT
AGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCA
GTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGA
AACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACC
TTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATC
CCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTT
CAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAAT
GTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCC
AATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGAC
TGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACAC
ACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACAT
TTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATG
GCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTA
AAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGA
AAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTA
GTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCT
TCCCCCTTTCCATATTATAATCTCATTTGATTGCTCTGCAGTTGGGAACGGTGATCTTCTTGAATGATGTTTCAGTGTGCAAAAACTATA
GAGCCTGTCAGCACCAAAGCTGACAGAAGTTATACCTTACTCCTTTCCTTTCCCCTGAACAAACCTGCTAATCCCACTAATTCAGGAATT
TGAGTAGAGATGGGGAACAAGAACCCAGATGCTGTCCCCTCACCCCCTCTCCTGTATTTCTCAGGTCCAGTTCAAATCTAAAATTCTACT
TTTAGAGTTGAAACAGAGTAATAACTTATCTAACCCTCTTTTCCTACAAAGGAGAAAGATAAAAGGCACAAAGGTTACCGCCAAGGCCCG
TCAGCTGTGTAGTGGCAAAGCCGAGACCGAGTCTCCTAAGTCCCCGTCAGTGTGGTTTTCACCACAGGACTGTCTCTTGTCGTTTTCCCC
TAATGCCTTCTCCTGCCTTTTCTGTGCCTAGTTTTTGGCTCTTCACATATTCCATATTGATTTTGACGCTCTGTATATTGGCATCAGGTG
GCAGCTGAATATCTTTTGAATTACTCGAAGGTAAAGCCAGATGCCAGAATGAAGGTGTAGCCAGTGTTTCCCATATGCCCCTGGAGCCCC
ACTTATTGAGGCCAGCAGAATAGGTGCAGAGATGAAGTGAGCTTAGAGATGTTGCAAATGCTCTTTATCCCTTCAGCTCTCTGATCTGCT
CTTTCTTCATGATACTTAGTCTGCAGGGCATATTAAGATCATCCCAGAGGTTCAGGCAGTTCCTGTCATCTCTGAAAAGACTGGGGGATA
TGAAATCTTCCCCCTACCCCACTTAATGCGTTGGATATGATTTTTCAAAGAATGCTTCATGCCCAAAATACCAGCCTGTTTAGCAGTGTT
ACACTGTTTGATCTGCGGGCACTTGTTGCATTGCCTGGCACCCAATATTCAGGGTCCATGACTAAGACTGGTCTTCTCAGATGCCCTGCT
TAAATCAGGGGCACTTCAGGCTCCACAGGCGTCATGTTGGACTGAGACCTAACTCACTGGACTCAGAGGAGGAATCGTGGAAAACAAGAG
CAAAACTACCCCACACCCCTATTTCATGTCTGAAATAACCCTGTTTCATACCAGTTGCAAAGCTTGTGGGGAGCGGTCCCACAAAGCACT
TTCTTAAACCTTGAGAATCTCCAAGAGAAAAATATTTGGGGAAGGAGGGAGGAAATATGTCCCTTGCACACCACCCCTGAAGCACATGGC
AGTAGGAAACAGCATAGGATTGTATGTGGGAGGTGGATAGGTCGGTGATGTGTGGAGCGGAAAAGCAGGTTGGTAAAGTTCCCTTCTTGG
GACTTATTCCTGGAGTCAGTGGATACAAGTAGTGCAGAAGGTTCACACTGCAAATAGTGTTCTCATCTCAAAGCAAACTATCATTCCAGA
AGGAAAAGTGTGTCAGGGCAAGCAGACAACACAATTTCCTATCAGAATATGTCCCTCAACCCCCGAAACAAGGCTTCTCTCAGCCTCCCC
ACCAGTGATGGATAACAGCTCCTATTCTCAGCTGACCTGACTGAGCCAACCCATGAACTCTTCACTCCTTGGGGAAGCCACCTCCCATCA
CACCCCTGAGCAGAGTTAGGGAGGAATTCTACTTCCCATAAAAGGACCTCTCCTGAGAGGCAAAACCTGTTGCCTCCACCACGGCTTCCC
TCTTGGCTCATTCCAAGCTTGGCCAAATTGGGGAAGTGGGATGGAGGTTGCCCTGCATCCCCCCTCCTCTGCCTGAGTGTGTCTTTGTAA
TGTCAGCTGGCATCATACAAAGAGCAGGAGAAGCAAACACCCAGAACTCTTTTGCTGGTCAGAGATTCCCTGAGTGTCTGTCCTCACCCA
AGCCTGCTCTGTGTCTGTGTTGTGAAGCTTGAGACTCTGGAAAGAAATGGGGAGGGGGGGCAGGGGAAATGTTGCCCTAAGAATGCTTCT
CATTCCTCTGTTCTTATTGGGTCCTGTTTTTCGGGAGGGTGGGGGTTGGGGGAAGCTTGACCTTGTGTCTTCGTCAATAAACTCACATTT

>In-frame_ENST00000467337_ENST00000262325_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=328AA_start in transcript=87_stop in transcript=1073
MENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQR
HRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIHTPLMPNQSIDVSLPLN
TLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKR

--------------------------------------------------------------
>In-frame_ENST00000467337_ENST00000592545_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1461nt_BP=542nt
GGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGGTGAGGGCGAGAAGGCCTCCGGATCTCAGGAAACAGGCTCGACAGCTG
GAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGT
TCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTT
ACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCAT
AGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCA
GTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGA
AACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACC
TTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATC
CCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTT
CAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAAT
GTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCC
AATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGAC
TGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACAC
ACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACAT
TTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATG
GCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTA

>In-frame_ENST00000467337_ENST00000592545_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=328AA_start in transcript=87_stop in transcript=1073
MENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQR
HRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIHTPLMPNQSIDVSLPLN
TLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKR

--------------------------------------------------------------
>In-frame_ENST00000467337_ENST00000538556_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1461nt_BP=542nt
GGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGGTGAGGGCGAGAAGGCCTCCGGATCTCAGGAAACAGGCTCGACAGCTG
GAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGT
TCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTT
ACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCAT
AGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCA
GTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGA
AACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACC
TTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATC
CCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTT
CAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAAT
GTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCC
AATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGAC
TGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACAC
ACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACAT
TTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATG
GCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTA

>In-frame_ENST00000467337_ENST00000538556_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=328AA_start in transcript=87_stop in transcript=1073
MENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQR
HRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIHTPLMPNQSIDVSLPLN
TLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKR

--------------------------------------------------------------
>In-frame_ENST00000467337_ENST00000312678_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1750nt_BP=542nt
GGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGGTGAGGGCGAGAAGGCCTCCGGATCTCAGGAAACAGGCTCGACAGCTG
GAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGT
TCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTT
ACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCAT
AGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCA
GTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGA
AACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACC
TTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATC
CCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTT
CAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAAT
GTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCC
AATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGAC
TGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACAC
ACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACAT
TTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATG
GCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTA
AAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGA
AAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTA
GTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCT

>In-frame_ENST00000467337_ENST00000312678_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=328AA_start in transcript=87_stop in transcript=1073
MENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQR
HRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIHTPLMPNQSIDVSLPLN
TLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKR

--------------------------------------------------------------
>In-frame_ENST00000467337_ENST00000589344_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1140nt_BP=542nt
GGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGGTGAGGGCGAGAAGGCCTCCGGATCTCAGGAAACAGGCTCGACAGCTG
GAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGT
TCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTT
ACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCAT
AGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCA
GTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGA
AACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACC
TTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATC
CCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTT
CAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAAT
GTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCC
AATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGAC

>In-frame_ENST00000467337_ENST00000589344_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=328AA_start in transcript=87_stop in transcript=1073
MENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQR
HRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIHTPLMPNQSIDVSLPLN
TLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKR

--------------------------------------------------------------
>In-frame_ENST00000467337_ENST00000537622_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1464nt_BP=542nt
GGACGACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGGTGAGGGCGAGAAGGCCTCCGGATCTCAGGAAACAGGCTCGACAGCTG
GAAAATGAACTTGACCTGAAACTAGTTTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGT
TCTGATACAACACCCCTTTTAAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTT
ACAGGGGTAAATGATAAAATGGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCAT
AGAGACATATTGCAGGATTATACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCA
GTACGAAAAGATATTGAGTCATATAAAAGTGGGTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGA
AACTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACC
TTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATC
CCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTT
CAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAAT
GTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCC
AATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGAC
TGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACAC
ACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACAT
TTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATG
GCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTA

>In-frame_ENST00000467337_ENST00000537622_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=328AA_start in transcript=87_stop in transcript=1073
MENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQR
HRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIHTPLMPNQSIDVSLPLN
TLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKR

--------------------------------------------------------------
>In-frame_ENST00000581721_ENST00000262325_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=3760nt_BP=510nt
GACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGT
TTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTT
AAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAAT
GGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTA
TACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGATGG
GTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGC
CATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAA
TAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAA
AATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGC
TGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCT
GAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCC
TGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCG
GTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTC
TAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTC
TTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTA
GTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCAC
TTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAG
TCCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAG
TTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCATATTATAATCTCATTTGATT
GCTCTGCAGTTGGGAACGGTGATCTTCTTGAATGATGTTTCAGTGTGCAAAAACTATAGAGCCTGTCAGCACCAAAGCTGACAGAAGTTA
TACCTTACTCCTTTCCTTTCCCCTGAACAAACCTGCTAATCCCACTAATTCAGGAATTTGAGTAGAGATGGGGAACAAGAACCCAGATGC
TGTCCCCTCACCCCCTCTCCTGTATTTCTCAGGTCCAGTTCAAATCTAAAATTCTACTTTTAGAGTTGAAACAGAGTAATAACTTATCTA
ACCCTCTTTTCCTACAAAGGAGAAAGATAAAAGGCACAAAGGTTACCGCCAAGGCCCGTCAGCTGTGTAGTGGCAAAGCCGAGACCGAGT
CTCCTAAGTCCCCGTCAGTGTGGTTTTCACCACAGGACTGTCTCTTGTCGTTTTCCCCTAATGCCTTCTCCTGCCTTTTCTGTGCCTAGT
TTTTGGCTCTTCACATATTCCATATTGATTTTGACGCTCTGTATATTGGCATCAGGTGGCAGCTGAATATCTTTTGAATTACTCGAAGGT
AAAGCCAGATGCCAGAATGAAGGTGTAGCCAGTGTTTCCCATATGCCCCTGGAGCCCCACTTATTGAGGCCAGCAGAATAGGTGCAGAGA
TGAAGTGAGCTTAGAGATGTTGCAAATGCTCTTTATCCCTTCAGCTCTCTGATCTGCTCTTTCTTCATGATACTTAGTCTGCAGGGCATA
TTAAGATCATCCCAGAGGTTCAGGCAGTTCCTGTCATCTCTGAAAAGACTGGGGGATATGAAATCTTCCCCCTACCCCACTTAATGCGTT
GGATATGATTTTTCAAAGAATGCTTCATGCCCAAAATACCAGCCTGTTTAGCAGTGTTACACTGTTTGATCTGCGGGCACTTGTTGCATT
GCCTGGCACCCAATATTCAGGGTCCATGACTAAGACTGGTCTTCTCAGATGCCCTGCTTAAATCAGGGGCACTTCAGGCTCCACAGGCGT
CATGTTGGACTGAGACCTAACTCACTGGACTCAGAGGAGGAATCGTGGAAAACAAGAGCAAAACTACCCCACACCCCTATTTCATGTCTG
AAATAACCCTGTTTCATACCAGTTGCAAAGCTTGTGGGGAGCGGTCCCACAAAGCACTTTCTTAAACCTTGAGAATCTCCAAGAGAAAAA
TATTTGGGGAAGGAGGGAGGAAATATGTCCCTTGCACACCACCCCTGAAGCACATGGCAGTAGGAAACAGCATAGGATTGTATGTGGGAG
GTGGATAGGTCGGTGATGTGTGGAGCGGAAAAGCAGGTTGGTAAAGTTCCCTTCTTGGGACTTATTCCTGGAGTCAGTGGATACAAGTAG
TGCAGAAGGTTCACACTGCAAATAGTGTTCTCATCTCAAAGCAAACTATCATTCCAGAAGGAAAAGTGTGTCAGGGCAAGCAGACAACAC
AATTTCCTATCAGAATATGTCCCTCAACCCCCGAAACAAGGCTTCTCTCAGCCTCCCCACCAGTGATGGATAACAGCTCCTATTCTCAGC
TGACCTGACTGAGCCAACCCATGAACTCTTCACTCCTTGGGGAAGCCACCTCCCATCACACCCCTGAGCAGAGTTAGGGAGGAATTCTAC
TTCCCATAAAAGGACCTCTCCTGAGAGGCAAAACCTGTTGCCTCCACCACGGCTTCCCTCTTGGCTCATTCCAAGCTTGGCCAAATTGGG
GAAGTGGGATGGAGGTTGCCCTGCATCCCCCCTCCTCTGCCTGAGTGTGTCTTTGTAATGTCAGCTGGCATCATACAAAGAGCAGGAGAA
GCAAACACCCAGAACTCTTTTGCTGGTCAGAGATTCCCTGAGTGTCTGTCCTCACCCAAGCCTGCTCTGTGTCTGTGTTGTGAAGCTTGA
GACTCTGGAAAGAAATGGGGAGGGGGGGCAGGGGAAATGTTGCCCTAAGAATGCTTCTCATTCCTCTGTTCTTATTGGGTCCTGTTTTTC

>In-frame_ENST00000581721_ENST00000262325_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=344AA_start in transcript=7_stop in transcript=1041
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIDGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIH
TPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADT

--------------------------------------------------------------
>In-frame_ENST00000581721_ENST00000592545_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1429nt_BP=510nt
GACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGT
TTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTT
AAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAAT
GGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTA
TACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGATGG
GTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGC
CATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAA
TAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAA
AATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGC
TGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCT
GAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCC
TGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCG
GTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTC
TAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTC
TTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTA

>In-frame_ENST00000581721_ENST00000592545_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=344AA_start in transcript=7_stop in transcript=1041
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIDGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIH
TPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADT

--------------------------------------------------------------
>In-frame_ENST00000581721_ENST00000538556_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1429nt_BP=510nt
GACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGT
TTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTT
AAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAAT
GGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTA
TACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGATGG
GTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGC
CATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAA
TAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAA
AATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGC
TGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCT
GAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCC
TGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCG
GTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTC
TAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTC
TTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTA

>In-frame_ENST00000581721_ENST00000538556_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=344AA_start in transcript=7_stop in transcript=1041
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIDGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIH
TPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADT

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>In-frame_ENST00000581721_ENST00000312678_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1718nt_BP=510nt
GACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGT
TTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTT
AAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAAT
GGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTA
TACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGATGG
GTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGC
CATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAA
TAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAA
AATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGC
TGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCT
GAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCC
TGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCG
GTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTC
TAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTC
TTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTA
GTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCAC
TTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAG
TCCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAG
TTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCATATTATAATCTCATTTGATT

>In-frame_ENST00000581721_ENST00000312678_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=344AA_start in transcript=7_stop in transcript=1041
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIDGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIH
TPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADT

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>In-frame_ENST00000581721_ENST00000589344_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1108nt_BP=510nt
GACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGT
TTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTT
AAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAAT
GGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTA
TACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGATGG
GTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGC
CATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAA
TAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAA
AATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGC
TGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCT
GAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCC
TGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCG

>In-frame_ENST00000581721_ENST00000589344_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=344AA_start in transcript=7_stop in transcript=1041
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIDGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIH
TPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADT

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>In-frame_ENST00000581721_ENST00000537622_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(transcript)=1432nt_BP=510nt
GACAAAGATGGCGGCAGGGACCAGCAGTTACTGGGAAGATCTCAGGAAACAGGCTCGACAGCTGGAAAATGAACTTGACCTGAAACTAGT
TTCCTTCAGCAAACTATGTACAAGTTACAGTCATAGCAGTACCCGAGATGGAAGACGCGACAGGTATAGTTCTGATACAACACCCCTTTT
AAATGGATCAAGCCAAGACAGAATGTTTGAGACAATGGCGATTGAGATTGAACAACTTTTGGCAAGGCTTACAGGGGTAAATGATAAAAT
GGCAGAATATACCAACAGTGCAGGTGTCCCCTCCTTGAATGCAGCCCTGATGCATACATTACAGCGGCATAGAGACATATTGCAGGATTA
TACACATGAATTCCATAAAACCAAAGCAAACTTTATGGCAATACGGGAAAGGGAGAATCTTATGGGATCAGTACGAAAAGATATTGATGG
GTCTGGAGTAAACAACAGAAGAACTGAGCTATTTTTGAAAGAACATGACCACCTTCGAAACTTTGGTGTCATCCCCAGCACTCCTCTGGC
CATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAA
TAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAA
AATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGC
TGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCT
GAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCC
TGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCG
GTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTC
TAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTC
TTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTA

>In-frame_ENST00000581721_ENST00000537622_TCGA-55-6971-01A_GOSR1_chr17_28819771_+_AP2B1_chr17_34009714_length(amino acids)=344AA_start in transcript=7_stop in transcript=1041
MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAE
YTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIDGSGVNNRRTELFLKEHDHLRNFGVIPSTPLAIH
TPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADT

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Fusion Gene PPI Analysis for GOSR1-AP2B1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneAP2B1chr17:28819771chr17:34009714ENST000002623251521841_937760.6666666666666938.0ARRB1
TgeneAP2B1chr17:28819771chr17:34009714ENST000003126781622841_937774.6666666666666952.0ARRB1
TgeneAP2B1chr17:28819771chr17:34009714ENST000005376221622841_937774.6666666666666952.0ARRB1
TgeneAP2B1chr17:28819771chr17:34009714ENST000005385561622841_937703.6666666666666881.0ARRB1
TgeneAP2B1chr17:28819771chr17:34009714ENST000005893441622841_937774.6666666666666952.0ARRB1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GOSR1-AP2B1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GOSR1-AP2B1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneAP2B1C0086132Depressive Symptoms1PSYGENET