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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AKAP7-ESR1 (FusionGDB2 ID:3470)

Fusion Gene Summary for AKAP7-ESR1

check button Fusion gene summary
Fusion gene informationFusion gene name: AKAP7-ESR1
Fusion gene ID: 3470
HgeneTgene
Gene symbol

AKAP7

ESR1

Gene ID

9465

2099

Gene nameA-kinase anchoring protein 7estrogen receptor 1
SynonymsAKAP15|AKAP18ER|ESR|ESRA|ESTRR|Era|NR3A1
Cytomap

6q23.2

6q25.1-q25.2

Type of geneprotein-codingprotein-coding
DescriptionA-kinase anchoring protein 7A kinase (PRKA) anchor protein 7A-kinase anchor protein 18 kDaA-kinase anchor protein 9 kDaAKAP 18estrogen receptorE2 receptor alphaER-alphaestradiol receptorestrogen nuclear receptor alphaestrogen receptor alpha E1-E2-1-2estrogen receptor alpha E1-N2-E2-1-2nuclear receptor subfamily 3 group A member 1oestrogen receptor alpha
Modification date2020031320200329
UniProtAcc

Q9P0M2

P03372

Ensembl transtripts involved in fusion geneENST00000431975, ENST00000541650, 
ENST00000366358, ENST00000368123, 
ENST00000537868, ENST00000263050, 
ENST00000342266, ENST00000474850, 
ENST00000440973, ENST00000338799, 
ENST00000456483, ENST00000443427, 
ENST00000206249, ENST00000406599, 
ENST00000427531, ENST00000482101, 
Fusion gene scores* DoF score6 X 3 X 6=10810 X 10 X 6=600
# samples 712
** MAII scorelog2(7/108*10)=-0.625604485218502
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/600*10)=-2.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AKAP7 [Title/Abstract] AND ESR1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAKAP7(131466556)-ESR1(152415520), # samples:2
Anticipated loss of major functional domain due to fusion event.AKAP7-ESR1 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
AKAP7-ESR1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
AKAP7-ESR1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
AKAP7-ESR1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneESR1

GO:0006366

transcription by RNA polymerase II

15831516

TgeneESR1

GO:0010629

negative regulation of gene expression

21695196

TgeneESR1

GO:0030520

intracellular estrogen receptor signaling pathway

9841876

TgeneESR1

GO:0032355

response to estradiol

15304487

TgeneESR1

GO:0043124

negative regulation of I-kappaB kinase/NF-kappaB signaling

7651415|16043358

TgeneESR1

GO:0043433

negative regulation of DNA-binding transcription factor activity

10816575

TgeneESR1

GO:0043627

response to estrogen

11581164

TgeneESR1

GO:0045893

positive regulation of transcription, DNA-templated

9841876|20074560

TgeneESR1

GO:0045899

positive regulation of RNA polymerase II transcriptional preinitiation complex assembly

9841876

TgeneESR1

GO:0045944

positive regulation of transcription by RNA polymerase II

11544182|12047722|15345745|15831516|18563714

TgeneESR1

GO:0051091

positive regulation of DNA-binding transcription factor activity

9328340|10681512

TgeneESR1

GO:0071392

cellular response to estradiol stimulus

15831516


check buttonFusion gene breakpoints across AKAP7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ESR1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A08I-01AAKAP7chr6

131466556

+ESR1chr6

152415520

+
ChimerDB4BRCATCGA-A8-A08IAKAP7chr6

131466556

+ESR1chr6

152419866

+
ChimerDB4BRCATCGA-A8-A08I-01AAKAP7chr6

131466556

+ESR1chr6

152415520

+
ChimerDB4BRCATCGA-A8-A08I-01AAKAP7chr6

131466556

+ESR1chr6

152419867

+


Top

Fusion Gene ORF analysis for AKAP7-ESR1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000431975ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000431975ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000431975ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000431975ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000431975ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000431975ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152415520

+
5CDS-intronENST00000431975ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152415520

+
5CDS-intronENST00000431975ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000541650ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000541650ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000541650ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000541650ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000541650ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000541650ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152415520

+
5CDS-intronENST00000541650ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152415520

+
5CDS-intronENST00000541650ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152415520

+
3UTR-3CDSENST00000366358ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152415520

+
3UTR-3CDSENST00000366358ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152415520

+
3UTR-3CDSENST00000366358ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152415520

+
3UTR-3CDSENST00000366358ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152415520

+
3UTR-3CDSENST00000366358ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152415520

+
3UTR-3CDSENST00000366358ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152415520

+
3UTR-intronENST00000366358ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152415520

+
3UTR-intronENST00000366358ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000368123ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000368123ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000368123ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000368123ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000368123ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152415520

+
In-frameENST00000368123ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152415520

+
5CDS-intronENST00000368123ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152415520

+
5CDS-intronENST00000368123ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000537868ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000537868ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000537868ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000537868ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000537868ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000537868ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-intronENST00000537868ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-intronENST00000537868ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000263050ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000263050ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000263050ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000263050ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000263050ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000263050ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-intronENST00000263050ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-intronENST00000263050ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000342266ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000342266ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000342266ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000342266ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000342266ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000342266ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-intronENST00000342266ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-intronENST00000342266ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000474850ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000474850ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000474850ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000474850ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000474850ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-3CDSENST00000474850ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-intronENST00000474850ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152415520

+
intron-intronENST00000474850ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152415520

+
Frame-shiftENST00000431975ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000431975ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000431975ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000431975ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000431975ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000431975ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419866

+
5CDS-intronENST00000431975ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419866

+
5CDS-intronENST00000431975ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000541650ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000541650ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000541650ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000541650ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000541650ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000541650ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419866

+
5CDS-intronENST00000541650ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419866

+
5CDS-intronENST00000541650ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419866

+
3UTR-3CDSENST00000366358ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419866

+
3UTR-3CDSENST00000366358ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419866

+
3UTR-3CDSENST00000366358ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419866

+
3UTR-3CDSENST00000366358ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419866

+
3UTR-3CDSENST00000366358ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419866

+
3UTR-3CDSENST00000366358ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419866

+
3UTR-intronENST00000366358ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419866

+
3UTR-intronENST00000366358ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000368123ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000368123ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000368123ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000368123ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000368123ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000368123ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419866

+
5CDS-intronENST00000368123ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419866

+
5CDS-intronENST00000368123ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000537868ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000537868ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000537868ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000537868ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000537868ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000537868ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-intronENST00000537868ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-intronENST00000537868ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000263050ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000263050ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000263050ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000263050ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000263050ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000263050ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-intronENST00000263050ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-intronENST00000263050ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000342266ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000342266ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000342266ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000342266ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000342266ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000342266ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-intronENST00000342266ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-intronENST00000342266ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000474850ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000474850ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000474850ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000474850ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000474850ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-3CDSENST00000474850ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-intronENST00000474850ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419866

+
intron-intronENST00000474850ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419866

+
Frame-shiftENST00000431975ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000431975ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000431975ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000431975ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000431975ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000431975ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419867

+
5CDS-intronENST00000431975ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419867

+
5CDS-intronENST00000431975ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000541650ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000541650ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000541650ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000541650ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000541650ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000541650ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419867

+
5CDS-intronENST00000541650ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419867

+
5CDS-intronENST00000541650ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419867

+
3UTR-3CDSENST00000366358ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419867

+
3UTR-3CDSENST00000366358ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419867

+
3UTR-3CDSENST00000366358ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419867

+
3UTR-3CDSENST00000366358ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419867

+
3UTR-3CDSENST00000366358ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419867

+
3UTR-3CDSENST00000366358ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419867

+
3UTR-intronENST00000366358ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419867

+
3UTR-intronENST00000366358ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000368123ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000368123ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000368123ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000368123ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000368123ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419867

+
Frame-shiftENST00000368123ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419867

+
5CDS-intronENST00000368123ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419867

+
5CDS-intronENST00000368123ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000537868ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000537868ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000537868ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000537868ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000537868ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000537868ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-intronENST00000537868ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-intronENST00000537868ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000263050ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000263050ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000263050ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000263050ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000263050ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000263050ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-intronENST00000263050ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-intronENST00000263050ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000342266ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000342266ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000342266ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000342266ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000342266ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000342266ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-intronENST00000342266ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-intronENST00000342266ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000474850ENST00000440973AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000474850ENST00000338799AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000474850ENST00000456483AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000474850ENST00000443427AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000474850ENST00000206249AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-3CDSENST00000474850ENST00000406599AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-intronENST00000474850ENST00000427531AKAP7chr6

131466556

+ESR1chr6

152419867

+
intron-intronENST00000474850ENST00000482101AKAP7chr6

131466556

+ESR1chr6

152419867

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000431975AKAP7chr6131466556+ENST00000440973ESR1chr6152415520+497624998667189
ENST00000431975AKAP7chr6131466556+ENST00000338799ESR1chr6152415520+75524998667189
ENST00000431975AKAP7chr6131466556+ENST00000456483ESR1chr6152415520+497624998667189
ENST00000431975AKAP7chr6131466556+ENST00000443427ESR1chr6152415520+497624998667189
ENST00000431975AKAP7chr6131466556+ENST00000206249ESR1chr6152415520+497324998667189
ENST00000431975AKAP7chr6131466556+ENST00000406599ESR1chr6152415520+68024998667189
ENST00000541650AKAP7chr6131466556+ENST00000440973ESR1chr6152415520+490217527593188
ENST00000541650AKAP7chr6131466556+ENST00000338799ESR1chr6152415520+68117527593188
ENST00000541650AKAP7chr6131466556+ENST00000456483ESR1chr6152415520+490217527593188
ENST00000541650AKAP7chr6131466556+ENST00000443427ESR1chr6152415520+490217527593188
ENST00000541650AKAP7chr6131466556+ENST00000206249ESR1chr6152415520+489917527593188
ENST00000541650AKAP7chr6131466556+ENST00000406599ESR1chr6152415520+60617527593188
ENST00000368123AKAP7chr6131466556+ENST00000440973ESR1chr6152415520+48239611514167
ENST00000368123AKAP7chr6131466556+ENST00000338799ESR1chr6152415520+6029611514167
ENST00000368123AKAP7chr6131466556+ENST00000456483ESR1chr6152415520+48239611514167
ENST00000368123AKAP7chr6131466556+ENST00000443427ESR1chr6152415520+48239611514167
ENST00000368123AKAP7chr6131466556+ENST00000206249ESR1chr6152415520+48209611514167
ENST00000368123AKAP7chr6131466556+ENST00000406599ESR1chr6152415520+5279611514167

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000431975ENST00000440973AKAP7chr6131466556+ESR1chr6152415520+0.0022121810.99778783
ENST00000431975ENST00000338799AKAP7chr6131466556+ESR1chr6152415520+0.0004788520.99952114
ENST00000431975ENST00000456483AKAP7chr6131466556+ESR1chr6152415520+0.0022121810.99778783
ENST00000431975ENST00000443427AKAP7chr6131466556+ESR1chr6152415520+0.0022121810.99778783
ENST00000431975ENST00000206249AKAP7chr6131466556+ESR1chr6152415520+0.0025069490.997493
ENST00000431975ENST00000406599AKAP7chr6131466556+ESR1chr6152415520+0.000394710.99960536
ENST00000541650ENST00000440973AKAP7chr6131466556+ESR1chr6152415520+0.0019616150.99803835
ENST00000541650ENST00000338799AKAP7chr6131466556+ESR1chr6152415520+0.0004069910.9995931
ENST00000541650ENST00000456483AKAP7chr6131466556+ESR1chr6152415520+0.0019616150.99803835
ENST00000541650ENST00000443427AKAP7chr6131466556+ESR1chr6152415520+0.0019616150.99803835
ENST00000541650ENST00000206249AKAP7chr6131466556+ESR1chr6152415520+0.0022267530.99777323
ENST00000541650ENST00000406599AKAP7chr6131466556+ESR1chr6152415520+0.0003147230.9996853
ENST00000368123ENST00000440973AKAP7chr6131466556+ESR1chr6152415520+0.0033250030.996675
ENST00000368123ENST00000338799AKAP7chr6131466556+ESR1chr6152415520+0.0004392920.99956065
ENST00000368123ENST00000456483AKAP7chr6131466556+ESR1chr6152415520+0.0033250030.996675
ENST00000368123ENST00000443427AKAP7chr6131466556+ESR1chr6152415520+0.0033250030.996675
ENST00000368123ENST00000206249AKAP7chr6131466556+ESR1chr6152415520+0.0039337320.9960663
ENST00000368123ENST00000406599AKAP7chr6131466556+ESR1chr6152415520+0.0004161330.9995839

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Fusion Genomic Features for AKAP7-ESR1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
AKAP7chr6131466556+ESR1chr6152419866+1.96E-050.99998033
AKAP7chr6131466556+ESR1chr6152419866+1.96E-050.99998033
AKAP7chr6131466556+ESR1chr6152415519+3.62E-091
AKAP7chr6131466556+ESR1chr6152419866+1.96E-050.99998033
AKAP7chr6131466556+ESR1chr6152419866+1.96E-050.99998033
AKAP7chr6131466556+ESR1chr6152415519+3.62E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for AKAP7-ESR1


check button Go to

FGviewer for the breakpoints of chr6:131466556-chr6:152415520

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AKAP7

Q9P0M2

ESR1

P03372

FUNCTION: Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. {ECO:0000269|PubMed:10613906, ECO:0000269|PubMed:17244820}.FUNCTION: Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components. Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner. Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace RELA/p65 and associated coregulators from the promoter. Recruited to the NF-kappa-B response element of the CCL2 and IL8 promoters and can displace CREBBP. Present with NF-kappa-B components RELA/p65 and NFKB1/p50 on ERE sequences. Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response elements; the function involves CREBBP. Can activate the transcriptional activity of TFF1. Also mediates membrane-initiated estrogen signaling involving various kinase cascades. Isoform 3 is involved in activation of NOS3 and endothelial nitric oxide production. Isoforms lacking one or several functional domains are thought to modulate transcriptional activity by competitive ligand or DNA binding and/or heterodimerization with the full-length receptor. Essential for MTA1-mediated transcriptional regulation of BRCA1 and BCAS3. Isoform 3 can bind to ERE and inhibit isoform 1. {ECO:0000269|PubMed:10681512, ECO:0000269|PubMed:10816575, ECO:0000269|PubMed:11477071, ECO:0000269|PubMed:11682626, ECO:0000269|PubMed:14764652, ECO:0000269|PubMed:15078875, ECO:0000269|PubMed:15891768, ECO:0000269|PubMed:16043358, ECO:0000269|PubMed:16617102, ECO:0000269|PubMed:16684779, ECO:0000269|PubMed:17922032, ECO:0000269|PubMed:17932106, ECO:0000269|PubMed:18247370, ECO:0000269|PubMed:19350539, ECO:0000269|PubMed:20074560, ECO:0000269|PubMed:20705611, ECO:0000269|PubMed:21330404, ECO:0000269|PubMed:22083956, ECO:0000269|PubMed:7651415, ECO:0000269|PubMed:9328340}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAKAP7chr6:131466556chr6:152415520ENST00000368123+17219_22128.333333333333332327.0Nucleotide bindingCMP
HgeneAKAP7chr6:131466556chr6:152415520ENST00000431975+28219_22150.333333333333336349.0Nucleotide bindingCMP
HgeneAKAP7chr6:131466556chr6:152415520ENST00000342266+122_11082.0RegionNote=Required for membrane localization
HgeneAKAP7chr6:131466556chr6:152415520ENST00000342266+1252_65082.0RegionNote=RII-binding
HgeneAKAP7chr6:131466556chr6:152415520ENST00000368123+17294_34828.333333333333332327.0RegionPKA-RII-alpha subunit binding domain
HgeneAKAP7chr6:131466556chr6:152415520ENST00000368123+17295_31928.333333333333332327.0RegionRI-alpha-binding
HgeneAKAP7chr6:131466556chr6:152415520ENST00000368123+17296_30928.333333333333332327.0RegionNote=RII-binding
HgeneAKAP7chr6:131466556chr6:152415520ENST00000431975+28294_34850.333333333333336349.0RegionPKA-RII-alpha subunit binding domain
HgeneAKAP7chr6:131466556chr6:152415520ENST00000431975+28295_31950.333333333333336349.0RegionRI-alpha-binding
HgeneAKAP7chr6:131466556chr6:152415520ENST00000431975+28296_30950.333333333333336349.0RegionNote=RII-binding
HgeneAKAP7chr6:131466556chr6:152415520ENST00000474850+132_110105.0RegionNote=Required for membrane localization
HgeneAKAP7chr6:131466556chr6:152415520ENST00000474850+1352_650105.0RegionNote=RII-binding
TgeneESR1chr6:131466556chr6:152415520ENST0000020624958185_250456.3333333333333596.0DNA bindingNuclear receptor
TgeneESR1chr6:131466556chr6:152415520ENST0000033879969185_250456.3333333333333596.0DNA bindingNuclear receptor
TgeneESR1chr6:131466556chr6:152415520ENST00000440973710185_250456.3333333333333596.0DNA bindingNuclear receptor
TgeneESR1chr6:131466556chr6:152415520ENST0000044342769185_250456.3333333333333596.0DNA bindingNuclear receptor
TgeneESR1chr6:131466556chr6:152415520ENST0000045648358185_250344.3333333333333484.0DNA bindingNuclear receptor
TgeneESR1chr6:131466556chr6:152415520ENST0000020624958311_547456.3333333333333596.0DomainNR LBD
TgeneESR1chr6:131466556chr6:152415520ENST0000033879969311_547456.3333333333333596.0DomainNR LBD
TgeneESR1chr6:131466556chr6:152415520ENST00000440973710311_547456.3333333333333596.0DomainNR LBD
TgeneESR1chr6:131466556chr6:152415520ENST0000044342769311_547456.3333333333333596.0DomainNR LBD
TgeneESR1chr6:131466556chr6:152415520ENST0000045648358311_547344.3333333333333484.0DomainNR LBD
TgeneESR1chr6:131466556chr6:152415520ENST0000020624958251_310456.3333333333333596.0RegionNote=Hinge
TgeneESR1chr6:131466556chr6:152415520ENST0000020624958264_595456.3333333333333596.0RegionNote=Self-association
TgeneESR1chr6:131466556chr6:152415520ENST0000020624958311_595456.3333333333333596.0RegionNote=Transactivation AF-2
TgeneESR1chr6:131466556chr6:152415520ENST0000033879969251_310456.3333333333333596.0RegionNote=Hinge
TgeneESR1chr6:131466556chr6:152415520ENST0000033879969264_595456.3333333333333596.0RegionNote=Self-association
TgeneESR1chr6:131466556chr6:152415520ENST0000033879969311_595456.3333333333333596.0RegionNote=Transactivation AF-2
TgeneESR1chr6:131466556chr6:152415520ENST00000440973710251_310456.3333333333333596.0RegionNote=Hinge
TgeneESR1chr6:131466556chr6:152415520ENST00000440973710264_595456.3333333333333596.0RegionNote=Self-association
TgeneESR1chr6:131466556chr6:152415520ENST00000440973710311_595456.3333333333333596.0RegionNote=Transactivation AF-2
TgeneESR1chr6:131466556chr6:152415520ENST0000044342769251_310456.3333333333333596.0RegionNote=Hinge
TgeneESR1chr6:131466556chr6:152415520ENST0000044342769264_595456.3333333333333596.0RegionNote=Self-association
TgeneESR1chr6:131466556chr6:152415520ENST0000044342769311_595456.3333333333333596.0RegionNote=Transactivation AF-2
TgeneESR1chr6:131466556chr6:152415520ENST0000045648358251_310344.3333333333333484.0RegionNote=Hinge
TgeneESR1chr6:131466556chr6:152415520ENST0000045648358264_595344.3333333333333484.0RegionNote=Self-association
TgeneESR1chr6:131466556chr6:152415520ENST0000045648358311_595344.3333333333333484.0RegionNote=Transactivation AF-2
TgeneESR1chr6:131466556chr6:152415520ENST0000020624958185_205456.3333333333333596.0Zinc fingerNR C4-type
TgeneESR1chr6:131466556chr6:152415520ENST0000020624958221_245456.3333333333333596.0Zinc fingerNR C4-type
TgeneESR1chr6:131466556chr6:152415520ENST0000033879969185_205456.3333333333333596.0Zinc fingerNR C4-type
TgeneESR1chr6:131466556chr6:152415520ENST0000033879969221_245456.3333333333333596.0Zinc fingerNR C4-type
TgeneESR1chr6:131466556chr6:152415520ENST00000440973710185_205456.3333333333333596.0Zinc fingerNR C4-type
TgeneESR1chr6:131466556chr6:152415520ENST00000440973710221_245456.3333333333333596.0Zinc fingerNR C4-type
TgeneESR1chr6:131466556chr6:152415520ENST0000044342769185_205456.3333333333333596.0Zinc fingerNR C4-type
TgeneESR1chr6:131466556chr6:152415520ENST0000044342769221_245456.3333333333333596.0Zinc fingerNR C4-type
TgeneESR1chr6:131466556chr6:152415520ENST0000045648358185_205344.3333333333333484.0Zinc fingerNR C4-type
TgeneESR1chr6:131466556chr6:152415520ENST0000045648358221_245344.3333333333333484.0Zinc fingerNR C4-type


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Fusion Gene Sequence for AKAP7-ESR1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000431975_ENST00000440973_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4976nt_BP=249nt
GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG
CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG
AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA
GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG
GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC
ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA
GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA
TCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCTGCTGCATTTTACCCTC
ATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAGATGAGTGGCCATTCAT
TTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATCTTTGTAACAGCTCTCT
TTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGGCTCAGATAACTCTGTG
CATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCTCTAAGAATAAGCCACA
GCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTCTTGTATTCCTATGGCA
ATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAATTCATTCCCCCTATAGG
AATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCAGATGTGCTGAAAGCTC
TGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGATCTTAGTTAAGTCTCCC
TATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTGCAGTAAGGTCAGCTTC
AGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCACTGTGGTGATGCATGA
TGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGTACTTGTGCAGGATTGT
TGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTCAGGGTGGCCCTGCCAC
AGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGTAGTCCAGCTCTTCTTC
ATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGCCCAGCACCCTGGGGCA
CGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGGTGGTTTAGAGATAATC
CAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTCCTGCCAGCTCATTTCC
TTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTTGCTTCTCTAGCACAAT
TATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGAAACCCTATTGAGAGGT
GATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGATTTCATTCATTTCTGAT
TGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACTTAAATTTGGGGACAAT
TTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGTTTGTTTAAGAAGCACC
TTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTTCTGGATTTAATTTGAC
TGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTTGTCATGTATACAGTCA
TTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAGACAAAATAGCACTAAT
CCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTATTCAGGGCAGCTAATT
TTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTTATACTTAGATTTTCTT
TTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATTATACAGTGGAAGGTTT
TACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGATGATTGAAATGTTCGCC
CAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTTCTGGCTGATGTTGGTA
TTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTAAAAGATGTGATTTATC
TGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGAAAGTATTTGGAGGAAA
ATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTCCATTTACAGCCATTTC
TAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTGTGTTTCTTTTCGCCAT
TGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAGACCCTATCAATGTAGG
TTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACCAAGCCATAGCCCATGC
CTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAAATCTTATACACTGAAA
TGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATTCATACTTTCCAATTAT
GAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTGGGGAAGCTAGTTATGT
GAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGATCTAGATTACACTGCA
CCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTTTTCAGTAGCGTTAATT
ATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGTTTTCTAAGTAATTGCT
GCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATCCAATTGTGCCTGAACT
TTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAACAACATATTGTCCCAT
GAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAGTGACATTATGCCAGTT
TCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATGGGAAAAGGCTCAAATG
CCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGCAGCTTTGCTTTGTTTA
ATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAATTTTCTCAACCTATTTG

>In-frame_ENST00000431975_ENST00000440973_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=189AA_start in transcript=98_stop in transcript=667
MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT
LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG

--------------------------------------------------------------
>In-frame_ENST00000431975_ENST00000338799_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=755nt_BP=249nt
GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG
CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG
AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA
GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG
GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC
ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA
GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA
TCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCTGCTGCATTTTACCCTC

>In-frame_ENST00000431975_ENST00000338799_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=189AA_start in transcript=98_stop in transcript=667
MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT
LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG

--------------------------------------------------------------
>In-frame_ENST00000431975_ENST00000456483_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4976nt_BP=249nt
GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG
CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG
AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA
GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG
GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC
ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA
GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA
TCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCTGCTGCATTTTACCCTC
ATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAGATGAGTGGCCATTCAT
TTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATCTTTGTAACAGCTCTCT
TTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGGCTCAGATAACTCTGTG
CATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCTCTAAGAATAAGCCACA
GCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTCTTGTATTCCTATGGCA
ATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAATTCATTCCCCCTATAGG
AATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCAGATGTGCTGAAAGCTC
TGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGATCTTAGTTAAGTCTCCC
TATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTGCAGTAAGGTCAGCTTC
AGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCACTGTGGTGATGCATGA
TGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGTACTTGTGCAGGATTGT
TGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTCAGGGTGGCCCTGCCAC
AGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGTAGTCCAGCTCTTCTTC
ATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGCCCAGCACCCTGGGGCA
CGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGGTGGTTTAGAGATAATC
CAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTCCTGCCAGCTCATTTCC
TTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTTGCTTCTCTAGCACAAT
TATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGAAACCCTATTGAGAGGT
GATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGATTTCATTCATTTCTGAT
TGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACTTAAATTTGGGGACAAT
TTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGTTTGTTTAAGAAGCACC
TTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTTCTGGATTTAATTTGAC
TGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTTGTCATGTATACAGTCA
TTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAGACAAAATAGCACTAAT
CCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTATTCAGGGCAGCTAATT
TTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTTATACTTAGATTTTCTT
TTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATTATACAGTGGAAGGTTT
TACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGATGATTGAAATGTTCGCC
CAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTTCTGGCTGATGTTGGTA
TTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTAAAAGATGTGATTTATC
TGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGAAAGTATTTGGAGGAAA
ATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTCCATTTACAGCCATTTC
TAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTGTGTTTCTTTTCGCCAT
TGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAGACCCTATCAATGTAGG
TTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACCAAGCCATAGCCCATGC
CTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAAATCTTATACACTGAAA
TGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATTCATACTTTCCAATTAT
GAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTGGGGAAGCTAGTTATGT
GAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGATCTAGATTACACTGCA
CCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTTTTCAGTAGCGTTAATT
ATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGTTTTCTAAGTAATTGCT
GCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATCCAATTGTGCCTGAACT
TTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAACAACATATTGTCCCAT
GAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAGTGACATTATGCCAGTT
TCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATGGGAAAAGGCTCAAATG
CCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGCAGCTTTGCTTTGTTTA
ATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAATTTTCTCAACCTATTTG

>In-frame_ENST00000431975_ENST00000456483_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=189AA_start in transcript=98_stop in transcript=667
MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT
LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG

--------------------------------------------------------------
>In-frame_ENST00000431975_ENST00000443427_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4976nt_BP=249nt
GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG
CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG
AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA
GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG
GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC
ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA
GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA
TCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCTGCTGCATTTTACCCTC
ATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAGATGAGTGGCCATTCAT
TTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATCTTTGTAACAGCTCTCT
TTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGGCTCAGATAACTCTGTG
CATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCTCTAAGAATAAGCCACA
GCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTCTTGTATTCCTATGGCA
ATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAATTCATTCCCCCTATAGG
AATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCAGATGTGCTGAAAGCTC
TGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGATCTTAGTTAAGTCTCCC
TATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTGCAGTAAGGTCAGCTTC
AGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCACTGTGGTGATGCATGA
TGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGTACTTGTGCAGGATTGT
TGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTCAGGGTGGCCCTGCCAC
AGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGTAGTCCAGCTCTTCTTC
ATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGCCCAGCACCCTGGGGCA
CGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGGTGGTTTAGAGATAATC
CAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTCCTGCCAGCTCATTTCC
TTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTTGCTTCTCTAGCACAAT
TATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGAAACCCTATTGAGAGGT
GATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGATTTCATTCATTTCTGAT
TGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACTTAAATTTGGGGACAAT
TTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGTTTGTTTAAGAAGCACC
TTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTTCTGGATTTAATTTGAC
TGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTTGTCATGTATACAGTCA
TTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAGACAAAATAGCACTAAT
CCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTATTCAGGGCAGCTAATT
TTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTTATACTTAGATTTTCTT
TTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATTATACAGTGGAAGGTTT
TACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGATGATTGAAATGTTCGCC
CAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTTCTGGCTGATGTTGGTA
TTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTAAAAGATGTGATTTATC
TGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGAAAGTATTTGGAGGAAA
ATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTCCATTTACAGCCATTTC
TAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTGTGTTTCTTTTCGCCAT
TGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAGACCCTATCAATGTAGG
TTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACCAAGCCATAGCCCATGC
CTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAAATCTTATACACTGAAA
TGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATTCATACTTTCCAATTAT
GAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTGGGGAAGCTAGTTATGT
GAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGATCTAGATTACACTGCA
CCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTTTTCAGTAGCGTTAATT
ATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGTTTTCTAAGTAATTGCT
GCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATCCAATTGTGCCTGAACT
TTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAACAACATATTGTCCCAT
GAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAGTGACATTATGCCAGTT
TCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATGGGAAAAGGCTCAAATG
CCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGCAGCTTTGCTTTGTTTA
ATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAATTTTCTCAACCTATTTG

>In-frame_ENST00000431975_ENST00000443427_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=189AA_start in transcript=98_stop in transcript=667
MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT
LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG

--------------------------------------------------------------
>In-frame_ENST00000431975_ENST00000206249_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4973nt_BP=249nt
GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG
CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG
AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA
GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG
GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC
ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA
GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA
TCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCTGCTGCATTTTACCCTC
ATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAGATGAGTGGCCATTCAT
TTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATCTTTGTAACAGCTCTCT
TTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGGCTCAGATAACTCTGTG
CATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCTCTAAGAATAAGCCACA
GCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTCTTGTATTCCTATGGCA
ATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAATTCATTCCCCCTATAGG
AATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCAGATGTGCTGAAAGCTC
TGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGATCTTAGTTAAGTCTCCC
TATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTGCAGTAAGGTCAGCTTC
AGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCACTGTGGTGATGCATGA
TGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGTACTTGTGCAGGATTGT
TGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTCAGGGTGGCCCTGCCAC
AGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGTAGTCCAGCTCTTCTTC
ATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGCCCAGCACCCTGGGGCA
CGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGGTGGTTTAGAGATAATC
CAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTCCTGCCAGCTCATTTCC
TTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTTGCTTCTCTAGCACAAT
TATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGAAACCCTATTGAGAGGT
GATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGATTTCATTCATTTCTGAT
TGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACTTAAATTTGGGGACAAT
TTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGTTTGTTTAAGAAGCACC
TTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTTCTGGATTTAATTTGAC
TGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTTGTCATGTATACAGTCA
TTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAGACAAAATAGCACTAAT
CCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTATTCAGGGCAGCTAATT
TTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTTATACTTAGATTTTCTT
TTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATTATACAGTGGAAGGTTT
TACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGATGATTGAAATGTTCGCC
CAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTTCTGGCTGATGTTGGTA
TTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTAAAAGATGTGATTTATC
TGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGAAAGTATTTGGAGGAAA
ATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTCCATTTACAGCCATTTC
TAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTGTGTTTCTTTTCGCCAT
TGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAGACCCTATCAATGTAGG
TTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACCAAGCCATAGCCCATGC
CTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAAATCTTATACACTGAAA
TGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATTCATACTTTCCAATTAT
GAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTGGGGAAGCTAGTTATGT
GAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGATCTAGATTACACTGCA
CCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTTTTCAGTAGCGTTAATT
ATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGTTTTCTAAGTAATTGCT
GCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATCCAATTGTGCCTGAACT
TTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAACAACATATTGTCCCAT
GAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAGTGACATTATGCCAGTT
TCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATGGGAAAAGGCTCAAATG
CCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGCAGCTTTGCTTTGTTTA
ATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAATTTTCTCAACCTATTTG

>In-frame_ENST00000431975_ENST00000206249_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=189AA_start in transcript=98_stop in transcript=667
MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT
LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG

--------------------------------------------------------------
>In-frame_ENST00000431975_ENST00000406599_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=680nt_BP=249nt
GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG
CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG
AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA
GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG
GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC
ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA
GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA

>In-frame_ENST00000431975_ENST00000406599_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=189AA_start in transcript=98_stop in transcript=667
MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT
LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG

--------------------------------------------------------------
>In-frame_ENST00000541650_ENST00000440973_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4902nt_BP=175nt
GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA
ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG
TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC
CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT
AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC
CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC
TTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCT
GCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAG
ATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATC
TTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGG
CTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCT
CTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTC
TTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAAT
TCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCA
GATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGAT
CTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTG
CAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCA
CTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGT
ACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTC
AGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGT
AGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGC
CCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGG
TGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTC
CTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTT
GCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGA
AACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGAT
TTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACT
TAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGT
TTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTT
CTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTT
GTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAG
ACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTA
TTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTT
ATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATT
ATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGAT
GATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTT
CTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTA
AAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGA
AAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTC
CATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTG
TGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAG
ACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACC
AAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAA
ATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATT
CATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTG
GGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGA
TCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTT
TTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGT
TTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATC
CAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAA
CAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAG
TGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATG
GGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGC
AGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAAT

>In-frame_ENST00000541650_ENST00000440973_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=188AA_start in transcript=27_stop in transcript=593
MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL
QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE

--------------------------------------------------------------
>In-frame_ENST00000541650_ENST00000338799_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=681nt_BP=175nt
GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA
ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG
TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC
CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT
AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC
CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC
TTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCT

>In-frame_ENST00000541650_ENST00000338799_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=188AA_start in transcript=27_stop in transcript=593
MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL
QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE

--------------------------------------------------------------
>In-frame_ENST00000541650_ENST00000456483_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4902nt_BP=175nt
GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA
ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG
TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC
CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT
AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC
CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC
TTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCT
GCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAG
ATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATC
TTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGG
CTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCT
CTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTC
TTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAAT
TCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCA
GATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGAT
CTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTG
CAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCA
CTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGT
ACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTC
AGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGT
AGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGC
CCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGG
TGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTC
CTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTT
GCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGA
AACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGAT
TTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACT
TAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGT
TTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTT
CTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTT
GTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAG
ACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTA
TTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTT
ATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATT
ATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGAT
GATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTT
CTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTA
AAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGA
AAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTC
CATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTG
TGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAG
ACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACC
AAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAA
ATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATT
CATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTG
GGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGA
TCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTT
TTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGT
TTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATC
CAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAA
CAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAG
TGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATG
GGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGC
AGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAAT

>In-frame_ENST00000541650_ENST00000456483_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=188AA_start in transcript=27_stop in transcript=593
MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL
QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE

--------------------------------------------------------------
>In-frame_ENST00000541650_ENST00000443427_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4902nt_BP=175nt
GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA
ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG
TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC
CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT
AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC
CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC
TTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCT
GCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAG
ATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATC
TTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGG
CTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCT
CTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTC
TTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAAT
TCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCA
GATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGAT
CTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTG
CAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCA
CTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGT
ACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTC
AGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGT
AGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGC
CCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGG
TGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTC
CTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTT
GCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGA
AACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGAT
TTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACT
TAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGT
TTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTT
CTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTT
GTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAG
ACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTA
TTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTT
ATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATT
ATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGAT
GATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTT
CTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTA
AAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGA
AAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTC
CATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTG
TGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAG
ACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACC
AAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAA
ATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATT
CATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTG
GGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGA
TCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTT
TTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGT
TTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATC
CAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAA
CAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAG
TGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATG
GGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGC
AGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAAT

>In-frame_ENST00000541650_ENST00000443427_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=188AA_start in transcript=27_stop in transcript=593
MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL
QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE

--------------------------------------------------------------
>In-frame_ENST00000541650_ENST00000206249_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4899nt_BP=175nt
GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA
ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG
TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC
CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT
AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC
CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC
TTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCT
GCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAG
ATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATC
TTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGG
CTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCT
CTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTC
TTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAAT
TCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCA
GATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGAT
CTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTG
CAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCA
CTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGT
ACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTC
AGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGT
AGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGC
CCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGG
TGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTC
CTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTT
GCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGA
AACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGAT
TTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACT
TAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGT
TTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTT
CTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTT
GTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAG
ACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTA
TTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTT
ATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATT
ATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGAT
GATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTT
CTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTA
AAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGA
AAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTC
CATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTG
TGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAG
ACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACC
AAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAA
ATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATT
CATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTG
GGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGA
TCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTT
TTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGT
TTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATC
CAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAA
CAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAG
TGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATG
GGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGC
AGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAAT

>In-frame_ENST00000541650_ENST00000206249_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=188AA_start in transcript=27_stop in transcript=593
MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL
QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE

--------------------------------------------------------------
>In-frame_ENST00000541650_ENST00000406599_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=606nt_BP=175nt
GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA
ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG
TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC
CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT
AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC
CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC

>In-frame_ENST00000541650_ENST00000406599_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=188AA_start in transcript=27_stop in transcript=593
MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL
QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE

--------------------------------------------------------------
>In-frame_ENST00000368123_ENST00000440973_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4823nt_BP=96nt
GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT
GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA
CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA
GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG
ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT
CATCGCATTCCTTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTC
AGATAATCCCTGCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAA
TGGCTTTCTAGATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCC
AAGGCTAAATCTTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCT
ATGGGTTGGGGCTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTT
TTTAAATGGCTCTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATT
ATAGCACCCTCTTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGG
TGATTGTCAATTCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACA
CTGCAGATTCAGATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGC
AGCAAGTTGATCTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCT
CCCTGAACTTGCAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGG
TGAACTGTTCACTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGG
AGCTGAACAGTACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGC
CAGACTTGCTCAGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGG
ATCCCTGGGGTAGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTC
CTACAATTGGCCCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACG
TATGCCCTTGGTGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTAC
CGCCTCCACTCCTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTC
CCTGGGCCTTTGCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTG
TCTGTAATTGAAACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTG
GAAAAGTGGATTTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTT
TTATGTGCACTTAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGA
AGCACCTTAGTTTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTA
GTAATTCTGTTCTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTT
CAAGCTACCTTGTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGT
ATCCACAGTAGACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAA
AAGGAAAATTATTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCT
TTTTAATGTTTATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAA
GCCAAACAATTATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGA
GAACATCAGATGATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACA
GCAGATATTTTCTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAA
GTTAAAATGTAAAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAG
AAGAGTATTGAAAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAA
TCAACTAGCTCCATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAG
CTAGTGGTCTGTGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCAT
CCAAAGAGAAGACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGA
TATGTTTAACCAAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTT
CTCACCTTGAAATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAAT
ACTTTCCTATTCATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGC
AGATCTGCTTGGGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCT
TGGGAGCGTGATCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAA
ATATCCATCTTTTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCA
TTTAAAATTGTTTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTT
TTTTTTGCATCCAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTG
CACCCTAGAAACAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTT
GAATTAATAAGTGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCT
CTTGTTTTATGGGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTC
GGTTTTGTCGCAGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCAC

>In-frame_ENST00000368123_ENST00000440973_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=167AA_start in transcript=11_stop in transcript=514
MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS

--------------------------------------------------------------
>In-frame_ENST00000368123_ENST00000338799_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=602nt_BP=96nt
GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT
GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA
CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA
GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG
ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT
CATCGCATTCCTTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTC

>In-frame_ENST00000368123_ENST00000338799_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=167AA_start in transcript=11_stop in transcript=514
MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS

--------------------------------------------------------------
>In-frame_ENST00000368123_ENST00000456483_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4823nt_BP=96nt
GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT
GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA
CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA
GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG
ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT
CATCGCATTCCTTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTC
AGATAATCCCTGCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAA
TGGCTTTCTAGATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCC
AAGGCTAAATCTTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCT
ATGGGTTGGGGCTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTT
TTTAAATGGCTCTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATT
ATAGCACCCTCTTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGG
TGATTGTCAATTCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACA
CTGCAGATTCAGATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGC
AGCAAGTTGATCTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCT
CCCTGAACTTGCAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGG
TGAACTGTTCACTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGG
AGCTGAACAGTACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGC
CAGACTTGCTCAGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGG
ATCCCTGGGGTAGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTC
CTACAATTGGCCCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACG
TATGCCCTTGGTGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTAC
CGCCTCCACTCCTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTC
CCTGGGCCTTTGCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTG
TCTGTAATTGAAACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTG
GAAAAGTGGATTTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTT
TTATGTGCACTTAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGA
AGCACCTTAGTTTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTA
GTAATTCTGTTCTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTT
CAAGCTACCTTGTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGT
ATCCACAGTAGACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAA
AAGGAAAATTATTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCT
TTTTAATGTTTATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAA
GCCAAACAATTATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGA
GAACATCAGATGATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACA
GCAGATATTTTCTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAA
GTTAAAATGTAAAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAG
AAGAGTATTGAAAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAA
TCAACTAGCTCCATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAG
CTAGTGGTCTGTGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCAT
CCAAAGAGAAGACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGA
TATGTTTAACCAAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTT
CTCACCTTGAAATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAAT
ACTTTCCTATTCATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGC
AGATCTGCTTGGGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCT
TGGGAGCGTGATCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAA
ATATCCATCTTTTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCA
TTTAAAATTGTTTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTT
TTTTTTGCATCCAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTG
CACCCTAGAAACAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTT
GAATTAATAAGTGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCT
CTTGTTTTATGGGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTC
GGTTTTGTCGCAGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCAC

>In-frame_ENST00000368123_ENST00000456483_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=167AA_start in transcript=11_stop in transcript=514
MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS

--------------------------------------------------------------
>In-frame_ENST00000368123_ENST00000443427_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4823nt_BP=96nt
GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT
GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA
CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA
GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG
ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT
CATCGCATTCCTTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTC
AGATAATCCCTGCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAA
TGGCTTTCTAGATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCC
AAGGCTAAATCTTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCT
ATGGGTTGGGGCTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTT
TTTAAATGGCTCTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATT
ATAGCACCCTCTTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGG
TGATTGTCAATTCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACA
CTGCAGATTCAGATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGC
AGCAAGTTGATCTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCT
CCCTGAACTTGCAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGG
TGAACTGTTCACTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGG
AGCTGAACAGTACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGC
CAGACTTGCTCAGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGG
ATCCCTGGGGTAGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTC
CTACAATTGGCCCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACG
TATGCCCTTGGTGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTAC
CGCCTCCACTCCTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTC
CCTGGGCCTTTGCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTG
TCTGTAATTGAAACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTG
GAAAAGTGGATTTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTT
TTATGTGCACTTAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGA
AGCACCTTAGTTTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTA
GTAATTCTGTTCTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTT
CAAGCTACCTTGTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGT
ATCCACAGTAGACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAA
AAGGAAAATTATTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCT
TTTTAATGTTTATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAA
GCCAAACAATTATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGA
GAACATCAGATGATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACA
GCAGATATTTTCTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAA
GTTAAAATGTAAAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAG
AAGAGTATTGAAAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAA
TCAACTAGCTCCATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAG
CTAGTGGTCTGTGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCAT
CCAAAGAGAAGACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGA
TATGTTTAACCAAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTT
CTCACCTTGAAATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAAT
ACTTTCCTATTCATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGC
AGATCTGCTTGGGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCT
TGGGAGCGTGATCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAA
ATATCCATCTTTTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCA
TTTAAAATTGTTTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTT
TTTTTTGCATCCAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTG
CACCCTAGAAACAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTT
GAATTAATAAGTGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCT
CTTGTTTTATGGGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTC
GGTTTTGTCGCAGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCAC

>In-frame_ENST00000368123_ENST00000443427_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=167AA_start in transcript=11_stop in transcript=514
MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS

--------------------------------------------------------------
>In-frame_ENST00000368123_ENST00000206249_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=4820nt_BP=96nt
GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT
GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA
CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA
GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG
ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT
CATCGCATTCCTTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTC
AGATAATCCCTGCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAA
TGGCTTTCTAGATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCC
AAGGCTAAATCTTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCT
ATGGGTTGGGGCTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTT
TTTAAATGGCTCTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATT
ATAGCACCCTCTTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGG
TGATTGTCAATTCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACA
CTGCAGATTCAGATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGC
AGCAAGTTGATCTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCT
CCCTGAACTTGCAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGG
TGAACTGTTCACTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGG
AGCTGAACAGTACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGC
CAGACTTGCTCAGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGG
ATCCCTGGGGTAGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTC
CTACAATTGGCCCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACG
TATGCCCTTGGTGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTAC
CGCCTCCACTCCTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTC
CCTGGGCCTTTGCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTG
TCTGTAATTGAAACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTG
GAAAAGTGGATTTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTT
TTATGTGCACTTAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGA
AGCACCTTAGTTTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTA
GTAATTCTGTTCTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTT
CAAGCTACCTTGTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGT
ATCCACAGTAGACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAA
AAGGAAAATTATTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCT
TTTTAATGTTTATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAA
GCCAAACAATTATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGA
GAACATCAGATGATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACA
GCAGATATTTTCTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAA
GTTAAAATGTAAAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAG
AAGAGTATTGAAAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAA
TCAACTAGCTCCATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAG
CTAGTGGTCTGTGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCAT
CCAAAGAGAAGACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGA
TATGTTTAACCAAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTT
CTCACCTTGAAATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAAT
ACTTTCCTATTCATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGC
AGATCTGCTTGGGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCT
TGGGAGCGTGATCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAA
ATATCCATCTTTTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCA
TTTAAAATTGTTTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTT
TTTTTTGCATCCAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTG
CACCCTAGAAACAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTT
GAATTAATAAGTGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCT
CTTGTTTTATGGGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTC
GGTTTTGTCGCAGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCAC

>In-frame_ENST00000368123_ENST00000206249_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=167AA_start in transcript=11_stop in transcript=514
MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS

--------------------------------------------------------------
>In-frame_ENST00000368123_ENST00000406599_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(transcript)=527nt_BP=96nt
GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT
GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA
CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA
GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG
ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT

>In-frame_ENST00000368123_ENST00000406599_TCGA-A8-A08I-01A_AKAP7_chr6_131466556_+_ESR1_chr6_152415520_length(amino acids)=167AA_start in transcript=11_stop in transcript=514
MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AKAP7-ESR1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneESR1chr6:131466556chr6:152415520ENST0000020624958262_595456.3333333333333596.0AKAP13
TgeneESR1chr6:131466556chr6:152415520ENST0000033879969262_595456.3333333333333596.0AKAP13
TgeneESR1chr6:131466556chr6:152415520ENST00000440973710262_595456.3333333333333596.0AKAP13
TgeneESR1chr6:131466556chr6:152415520ENST0000044342769262_595456.3333333333333596.0AKAP13
TgeneESR1chr6:131466556chr6:152415520ENST0000045648358262_595344.3333333333333484.0AKAP13
TgeneESR1chr6:131466556chr6:152415520ENST000002062495835_174456.3333333333333596.0DDX5%3B self-association
TgeneESR1chr6:131466556chr6:152415520ENST000003387996935_174456.3333333333333596.0DDX5%3B self-association
TgeneESR1chr6:131466556chr6:152415520ENST0000044097371035_174456.3333333333333596.0DDX5%3B self-association
TgeneESR1chr6:131466556chr6:152415520ENST000004434276935_174456.3333333333333596.0DDX5%3B self-association
TgeneESR1chr6:131466556chr6:152415520ENST000004564835835_174344.3333333333333484.0DDX5%3B self-association


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AKAP7-ESR1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneESR1P03372DB00286Conjugated estrogensAgonistSmall moleculeApproved
TgeneESR1P03372DB00286Conjugated estrogensAgonistSmall moleculeApproved
TgeneESR1P03372DB00286Conjugated estrogensAgonistSmall moleculeApproved
TgeneESR1P03372DB00304DesogestrelAgonistSmall moleculeApproved
TgeneESR1P03372DB00304DesogestrelAgonistSmall moleculeApproved
TgeneESR1P03372DB00304DesogestrelAgonistSmall moleculeApproved
TgeneESR1P03372DB00648MitotaneSmall moleculeApproved
TgeneESR1P03372DB00648MitotaneSmall moleculeApproved
TgeneESR1P03372DB00648MitotaneSmall moleculeApproved
TgeneESR1P03372DB00655EstroneAgonistSmall moleculeApproved
TgeneESR1P03372DB00655EstroneAgonistSmall moleculeApproved
TgeneESR1P03372DB00655EstroneAgonistSmall moleculeApproved
TgeneESR1P03372DB00675TamoxifenAgonist|AntagonistSmall moleculeApproved
TgeneESR1P03372DB00675TamoxifenAgonist|AntagonistSmall moleculeApproved
TgeneESR1P03372DB00675TamoxifenAgonist|AntagonistSmall moleculeApproved
TgeneESR1P03372DB00823Ethynodiol diacetateAgonistSmall moleculeApproved
TgeneESR1P03372DB00823Ethynodiol diacetateAgonistSmall moleculeApproved
TgeneESR1P03372DB00823Ethynodiol diacetateAgonistSmall moleculeApproved
TgeneESR1P03372DB00841DobutamineSmall moleculeApproved
TgeneESR1P03372DB00841DobutamineSmall moleculeApproved
TgeneESR1P03372DB00841DobutamineSmall moleculeApproved
TgeneESR1P03372DB00977EthinylestradiolAgonistSmall moleculeApproved
TgeneESR1P03372DB00977EthinylestradiolAgonistSmall moleculeApproved
TgeneESR1P03372DB00977EthinylestradiolAgonistSmall moleculeApproved
TgeneESR1P03372DB01357MestranolAgonistSmall moleculeApproved
TgeneESR1P03372DB01357MestranolAgonistSmall moleculeApproved
TgeneESR1P03372DB01357MestranolAgonistSmall moleculeApproved
TgeneESR1P03372DB01406DanazolAgonistSmall moleculeApproved
TgeneESR1P03372DB01406DanazolAgonistSmall moleculeApproved
TgeneESR1P03372DB01406DanazolAgonistSmall moleculeApproved
TgeneESR1P03372DB04574Estrone sulfateAgonistSmall moleculeApproved
TgeneESR1P03372DB04574Estrone sulfateAgonistSmall moleculeApproved
TgeneESR1P03372DB04574Estrone sulfateAgonistSmall moleculeApproved
TgeneESR1P03372DB04575QuinestrolAgonist|ModulatorSmall moleculeApproved
TgeneESR1P03372DB04575QuinestrolAgonist|ModulatorSmall moleculeApproved
TgeneESR1P03372DB04575QuinestrolAgonist|ModulatorSmall moleculeApproved
TgeneESR1P03372DB06710MethyltestosteroneSmall moleculeApproved
TgeneESR1P03372DB06710MethyltestosteroneSmall moleculeApproved
TgeneESR1P03372DB06710MethyltestosteroneSmall moleculeApproved
TgeneESR1P03372DB09086EugenolSmall moleculeApproved
TgeneESR1P03372DB09086EugenolSmall moleculeApproved
TgeneESR1P03372DB09086EugenolSmall moleculeApproved
TgeneESR1P03372DB09317Synthetic Conjugated Estrogens, ALigandSmall moleculeApproved
TgeneESR1P03372DB09317Synthetic Conjugated Estrogens, ALigandSmall moleculeApproved
TgeneESR1P03372DB09317Synthetic Conjugated Estrogens, ALigandSmall moleculeApproved
TgeneESR1P03372DB09318Synthetic Conjugated Estrogens, BLigandSmall moleculeApproved
TgeneESR1P03372DB09318Synthetic Conjugated Estrogens, BLigandSmall moleculeApproved
TgeneESR1P03372DB09318Synthetic Conjugated Estrogens, BLigandSmall moleculeApproved
TgeneESR1P03372DB09369Polyestradiol phosphateAgonistSmall moleculeApproved
TgeneESR1P03372DB09369Polyestradiol phosphateAgonistSmall moleculeApproved
TgeneESR1P03372DB09369Polyestradiol phosphateAgonistSmall moleculeApproved
TgeneESR1P03372DB09371NorethynodrelSmall moleculeApproved
TgeneESR1P03372DB09371NorethynodrelSmall moleculeApproved
TgeneESR1P03372DB09371NorethynodrelSmall moleculeApproved
TgeneESR1P03372DB11219EnzacameneSmall moleculeApproved
TgeneESR1P03372DB11219EnzacameneSmall moleculeApproved
TgeneESR1P03372DB11219EnzacameneSmall moleculeApproved
TgeneESR1P03372DB11619GestrinoneAgonist|AntagonistSmall moleculeApproved
TgeneESR1P03372DB11619GestrinoneAgonist|AntagonistSmall moleculeApproved
TgeneESR1P03372DB11619GestrinoneAgonist|AntagonistSmall moleculeApproved
TgeneESR1P03372DB13943Testosterone cypionateSmall moleculeApproved
TgeneESR1P03372DB13943Testosterone cypionateSmall moleculeApproved
TgeneESR1P03372DB13943Testosterone cypionateSmall moleculeApproved
TgeneESR1P03372DB13944Testosterone enanthateSmall moleculeApproved
TgeneESR1P03372DB13944Testosterone enanthateSmall moleculeApproved
TgeneESR1P03372DB13944Testosterone enanthateSmall moleculeApproved
TgeneESR1P03372DB15690Fluoroestradiol F-18BinderSmall moleculeApproved
TgeneESR1P03372DB15690Fluoroestradiol F-18BinderSmall moleculeApproved
TgeneESR1P03372DB15690Fluoroestradiol F-18BinderSmall moleculeApproved
TgeneESR1P03372DB14548Zinc sulfate, unspecified formBinderSmall moleculeApproved|Experimental
TgeneESR1P03372DB14548Zinc sulfate, unspecified formBinderSmall moleculeApproved|Experimental
TgeneESR1P03372DB14548Zinc sulfate, unspecified formBinderSmall moleculeApproved|Experimental
TgeneESR1P03372DB01185FluoxymesteroneAntagonistSmall moleculeApproved|Illicit
TgeneESR1P03372DB01185FluoxymesteroneAntagonistSmall moleculeApproved|Illicit
TgeneESR1P03372DB01185FluoxymesteroneAntagonistSmall moleculeApproved|Illicit
TgeneESR1P03372DB00255DiethylstilbestrolAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00255DiethylstilbestrolAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00255DiethylstilbestrolAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00367LevonorgestrelOther/unknownSmall moleculeApproved|Investigational
TgeneESR1P03372DB00367LevonorgestrelOther/unknownSmall moleculeApproved|Investigational
TgeneESR1P03372DB00367LevonorgestrelOther/unknownSmall moleculeApproved|Investigational
TgeneESR1P03372DB00481RaloxifeneAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00481RaloxifeneAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00481RaloxifeneAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00539ToremifeneModulatorSmall moleculeApproved|Investigational
TgeneESR1P03372DB00539ToremifeneModulatorSmall moleculeApproved|Investigational
TgeneESR1P03372DB00539ToremifeneModulatorSmall moleculeApproved|Investigational
TgeneESR1P03372DB00603Medroxyprogesterone acetateAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00603Medroxyprogesterone acetateAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00603Medroxyprogesterone acetateAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00624TestosteroneInhibitorSmall moleculeApproved|Investigational
TgeneESR1P03372DB00624TestosteroneInhibitorSmall moleculeApproved|Investigational
TgeneESR1P03372DB00624TestosteroneInhibitorSmall moleculeApproved|Investigational
TgeneESR1P03372DB00882ClomifeneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00882ClomifeneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00882ClomifeneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00890DienestrolAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00890DienestrolAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00890DienestrolAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00947FulvestrantAntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00947FulvestrantAntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00947FulvestrantAntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00957NorgestimateAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00957NorgestimateAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB00957NorgestimateAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB01196EstramustineAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB01196EstramustineAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB01196EstramustineAgonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB01428OxybenzoneSmall moleculeApproved|Investigational
TgeneESR1P03372DB01428OxybenzoneSmall moleculeApproved|Investigational
TgeneESR1P03372DB01428OxybenzoneSmall moleculeApproved|Investigational
TgeneESR1P03372DB01593ZincCofactorSmall moleculeApproved|Investigational
TgeneESR1P03372DB01593ZincCofactorSmall moleculeApproved|Investigational
TgeneESR1P03372DB01593ZincCofactorSmall moleculeApproved|Investigational
TgeneESR1P03372DB04930PermethrinSmall moleculeApproved|Investigational
TgeneESR1P03372DB04930PermethrinSmall moleculeApproved|Investigational
TgeneESR1P03372DB04930PermethrinSmall moleculeApproved|Investigational
TgeneESR1P03372DB04938OspemifeneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB04938OspemifeneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB04938OspemifeneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB06202LasofoxifeneAgonist|Antagonist|Negative modulatorSmall moleculeApproved|Investigational
TgeneESR1P03372DB06202LasofoxifeneAgonist|Antagonist|Negative modulatorSmall moleculeApproved|Investigational
TgeneESR1P03372DB06202LasofoxifeneAgonist|Antagonist|Negative modulatorSmall moleculeApproved|Investigational
TgeneESR1P03372DB06249ArzoxifeneSmall moleculeApproved|Investigational
TgeneESR1P03372DB06249ArzoxifeneSmall moleculeApproved|Investigational
TgeneESR1P03372DB06249ArzoxifeneSmall moleculeApproved|Investigational
TgeneESR1P03372DB06401BazedoxifeneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB06401BazedoxifeneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB06401BazedoxifeneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB09070TiboloneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB09070TiboloneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB09070TiboloneAgonist|AntagonistSmall moleculeApproved|Investigational
TgeneESR1P03372DB09535OctocryleneSmall moleculeApproved|Investigational
TgeneESR1P03372DB09535OctocryleneSmall moleculeApproved|Investigational
TgeneESR1P03372DB09535OctocryleneSmall moleculeApproved|Investigational
TgeneESR1P03372DB11064HomosalateSmall moleculeApproved|Investigational
TgeneESR1P03372DB11064HomosalateSmall moleculeApproved|Investigational
TgeneESR1P03372DB11064HomosalateSmall moleculeApproved|Investigational
TgeneESR1P03372DB13946Testosterone undecanoateSmall moleculeApproved|Investigational
TgeneESR1P03372DB13946Testosterone undecanoateSmall moleculeApproved|Investigational
TgeneESR1P03372DB13946Testosterone undecanoateSmall moleculeApproved|Investigational
TgeneESR1P03372DB14487Zinc acetateSmall moleculeApproved|Investigational
TgeneESR1P03372DB14487Zinc acetateSmall moleculeApproved|Investigational
TgeneESR1P03372DB14487Zinc acetateSmall moleculeApproved|Investigational
TgeneESR1P03372DB14533Zinc chlorideBinderSmall moleculeApproved|Investigational
TgeneESR1P03372DB14533Zinc chlorideBinderSmall moleculeApproved|Investigational
TgeneESR1P03372DB14533Zinc chlorideBinderSmall moleculeApproved|Investigational
TgeneESR1P03372DB01708PrasteroneBinderSmall moleculeApproved|Investigational|Nutraceutical
TgeneESR1P03372DB01708PrasteroneBinderSmall moleculeApproved|Investigational|Nutraceutical
TgeneESR1P03372DB01708PrasteroneBinderSmall moleculeApproved|Investigational|Nutraceutical
TgeneESR1P03372DB00783EstradiolAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB00783EstradiolAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB00783EstradiolAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB04573EstriolAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB04573EstriolAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB04573EstriolAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13952Estradiol acetateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13952Estradiol acetateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13952Estradiol acetateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13953Estradiol benzoateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13953Estradiol benzoateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13953Estradiol benzoateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13954Estradiol cypionateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13954Estradiol cypionateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13954Estradiol cypionateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13955Estradiol dienanthateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13955Estradiol dienanthateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13955Estradiol dienanthateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13956Estradiol valerateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13956Estradiol valerateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB13956Estradiol valerateAgonistSmall moleculeApproved|Investigational|Vet_approved
TgeneESR1P03372DB01108TrilostaneAllosteric modulatorSmall moleculeApproved|Investigational|Vet_approved|Withdrawn
TgeneESR1P03372DB01108TrilostaneAllosteric modulatorSmall moleculeApproved|Investigational|Vet_approved|Withdrawn
TgeneESR1P03372DB01108TrilostaneAllosteric modulatorSmall moleculeApproved|Investigational|Vet_approved|Withdrawn
TgeneESR1P03372DB01065MelatoninAntagonistSmall moleculeApproved|Nutraceutical|Vet_approved
TgeneESR1P03372DB01065MelatoninAntagonistSmall moleculeApproved|Nutraceutical|Vet_approved
TgeneESR1P03372DB01065MelatoninAntagonistSmall moleculeApproved|Nutraceutical|Vet_approved
TgeneESR1P03372DB00396ProgesteroneAgonist|Downregulator|InhibitorSmall moleculeApproved|Vet_approved
TgeneESR1P03372DB00396ProgesteroneAgonist|Downregulator|InhibitorSmall moleculeApproved|Vet_approved
TgeneESR1P03372DB00396ProgesteroneAgonist|Downregulator|InhibitorSmall moleculeApproved|Vet_approved
TgeneESR1P03372DB01183NaloxoneAntagonist|Other/unknownSmall moleculeApproved|Vet_approved
TgeneESR1P03372DB01183NaloxoneAntagonist|Other/unknownSmall moleculeApproved|Vet_approved
TgeneESR1P03372DB01183NaloxoneAntagonist|Other/unknownSmall moleculeApproved|Vet_approved
TgeneESR1P03372DB00431LindaneSmall moleculeApproved|Withdrawn
TgeneESR1P03372DB00431LindaneSmall moleculeApproved|Withdrawn
TgeneESR1P03372DB00431LindaneSmall moleculeApproved|Withdrawn
TgeneESR1P03372DB00756HexachloropheneSmall moleculeApproved|Withdrawn
TgeneESR1P03372DB00756HexachloropheneSmall moleculeApproved|Withdrawn
TgeneESR1P03372DB00756HexachloropheneSmall moleculeApproved|Withdrawn
TgeneESR1P03372DB04824PhenolphthaleinAgonistSmall moleculeApproved|Withdrawn
TgeneESR1P03372DB04824PhenolphthaleinAgonistSmall moleculeApproved|Withdrawn
TgeneESR1P03372DB04824PhenolphthaleinAgonistSmall moleculeApproved|Withdrawn
TgeneESR1P03372DB11478ZeranolSmall moleculeExperimental|Vet_approved
TgeneESR1P03372DB11478ZeranolSmall moleculeExperimental|Vet_approved
TgeneESR1P03372DB11478ZeranolSmall moleculeExperimental|Vet_approved
TgeneESR1P03372DB11541RactopamineSmall moleculeVet_approved
TgeneESR1P03372DB11541RactopamineSmall moleculeVet_approved
TgeneESR1P03372DB11541RactopamineSmall moleculeVet_approved

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Related Diseases for AKAP7-ESR1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAKAP7C0013146Drug abuse1CTD_human
HgeneAKAP7C0013170Drug habituation1CTD_human
HgeneAKAP7C0013222Drug Use Disorders1CTD_human
HgeneAKAP7C0029231Organic Mental Disorders, Substance-Induced1CTD_human
HgeneAKAP7C0038580Substance Dependence1CTD_human
HgeneAKAP7C0038586Substance Use Disorders1CTD_human
HgeneAKAP7C0236969Substance-Related Disorders1CTD_human
HgeneAKAP7C0740858Substance abuse problem1CTD_human
HgeneAKAP7C1510472Drug Dependence1CTD_human
HgeneAKAP7C4316881Prescription Drug Abuse1CTD_human
TgeneESR1C0006142Malignant neoplasm of breast14CGI;CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneESR1C0678222Breast Carcinoma14CGI;CTD_human
TgeneESR1C1257931Mammary Neoplasms, Human14CTD_human
TgeneESR1C1458155Mammary Neoplasms14CTD_human
TgeneESR1C4704874Mammary Carcinoma, Human14CTD_human
TgeneESR1C0005586Bipolar Disorder5PSYGENET
TgeneESR1C0011570Mental Depression5PSYGENET
TgeneESR1C0011581Depressive disorder5PSYGENET
TgeneESR1C0036341Schizophrenia5PSYGENET
TgeneESR1C0525045Mood Disorders4PSYGENET
TgeneESR1C3809250ESTROGEN RESISTANCE3GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneESR1C0001418Adenocarcinoma2CTD_human
TgeneESR1C0007097Carcinoma2CTD_human
TgeneESR1C0007621Neoplastic Cell Transformation2CTD_human
TgeneESR1C0010054Coronary Arteriosclerosis2CTD_human
TgeneESR1C0021364Male infertility2CTD_human
TgeneESR1C0024121Lung Neoplasms2CTD_human
TgeneESR1C0024667Animal Mammary Neoplasms2CTD_human
TgeneESR1C0025500Mesothelioma2CTD_human
TgeneESR1C0027626Neoplasm Invasiveness2CTD_human
TgeneESR1C0033578Prostatic Neoplasms2CTD_human
TgeneESR1C0205641Adenocarcinoma, Basal Cell2CTD_human
TgeneESR1C0205642Adenocarcinoma, Oxyphilic2CTD_human
TgeneESR1C0205643Carcinoma, Cribriform2CTD_human
TgeneESR1C0205644Carcinoma, Granular Cell2CTD_human
TgeneESR1C0205645Adenocarcinoma, Tubular2CTD_human
TgeneESR1C0205696Anaplastic carcinoma2CTD_human
TgeneESR1C0205697Carcinoma, Spindle-Cell2CTD_human
TgeneESR1C0205698Undifferentiated carcinoma2CTD_human
TgeneESR1C0205699Carcinomatosis2CTD_human
TgeneESR1C0242379Malignant neoplasm of lung2CTD_human
TgeneESR1C0376358Malignant neoplasm of prostate2CTD_human
TgeneESR1C0848676Subfertility, Male2CTD_human
TgeneESR1C0917731Male sterility2CTD_human
TgeneESR1C1257925Mammary Carcinoma, Animal2CTD_human
TgeneESR1C1956346Coronary Artery Disease2CTD_human
TgeneESR1C2239176Liver carcinoma2CTD_human
TgeneESR1C0002395Alzheimer's Disease1CTD_human
TgeneESR1C0004114Astrocytoma1CTD_human
TgeneESR1C0004153Atherosclerosis1CTD_human
TgeneESR1C0005684Malignant neoplasm of urinary bladder1CTD_human
TgeneESR1C0005695Bladder Neoplasm1CTD_human
TgeneESR1C0005940Bone Diseases1CTD_human
TgeneESR1C0005944Metabolic Bone Disorder1CTD_human
TgeneESR1C0007852Cervical Migraine Syndrome1CTD_human
TgeneESR1C0011265Presenile dementia1CTD_human
TgeneESR1C0014170Endometrial Neoplasms1CTD_human
TgeneESR1C0017658Glomerulonephritis1CTD_human
TgeneESR1C0018984Hemicrania migraine1CTD_human
TgeneESR1C0021361Female infertility1CTD_human
TgeneESR1C0023267Fibroid Tumor1CTD_human
TgeneESR1C0023418leukemia1CTD_human
TgeneESR1C0023903Liver neoplasms1CTD_human
TgeneESR1C0024668Mammary Neoplasms, Experimental1CTD_human
TgeneESR1C0024809Marijuana Abuse1PSYGENET
TgeneESR1C0026858Musculoskeletal Pain1CTD_human
TgeneESR1C0027051Myocardial Infarction1CTD_human
TgeneESR1C0027627Neoplasm Metastasis1CTD_human
TgeneESR1C0027643Neoplasm Recurrence, Local1CTD_human
TgeneESR1C0027819Neuroblastoma1CTD_human
TgeneESR1C0028754Obesity1CTD_human
TgeneESR1C0028960Oligospermia1CTD_human
TgeneESR1C0029453Osteopenia1CTD_human
TgeneESR1C0033937Psychoses, Drug1CTD_human
TgeneESR1C0033941Psychoses, Substance-Induced1CTD_human
TgeneESR1C0036939Shared Paranoid Disorder1PSYGENET
TgeneESR1C0038279Sterility, Postpartum1CTD_human
TgeneESR1C0042133Uterine Fibroids1CTD_human
TgeneESR1C0149931Migraine Disorders1CTD_human
TgeneESR1C0205768Subependymal Giant Cell Astrocytoma1CTD_human
TgeneESR1C0235874Disease Exacerbation1CTD_human
TgeneESR1C0270858Abdominal Migraine1CTD_human
TgeneESR1C0276496Familial Alzheimer Disease (FAD)1CTD_human
TgeneESR1C0280783Juvenile Pilocytic Astrocytoma1CTD_human
TgeneESR1C0280785Diffuse Astrocytoma1CTD_human
TgeneESR1C0282612Prostatic Intraepithelial Neoplasias1CTD_human
TgeneESR1C0334579Anaplastic astrocytoma1CTD_human
TgeneESR1C0334580Protoplasmic astrocytoma1CTD_human
TgeneESR1C0334581Gemistocytic astrocytoma1CTD_human
TgeneESR1C0334582Fibrillary Astrocytoma1CTD_human
TgeneESR1C0334583Pilocytic Astrocytoma1CTD_human
TgeneESR1C0338070Childhood Cerebral Astrocytoma1CTD_human
TgeneESR1C0338489Status Migrainosus1CTD_human
TgeneESR1C0341869Subfertility, Female1CTD_human
TgeneESR1C0345904Malignant neoplasm of liver1CTD_human
TgeneESR1C0476089Endometrial Carcinoma1CGI;CTD_human
TgeneESR1C0494463Alzheimer Disease, Late Onset1CTD_human
TgeneESR1C0521664Acute Confusional Migraine1CTD_human
TgeneESR1C0546126Acute Confusional Senile Dementia1CTD_human
TgeneESR1C0547065Mixed oligoastrocytoma1CTD_human
TgeneESR1C0700438Sick Headaches1CTD_human
TgeneESR1C0750900Alzheimer's Disease, Focal Onset1CTD_human
TgeneESR1C0750901Alzheimer Disease, Early Onset1CTD_human
TgeneESR1C0750935Cerebral Astrocytoma1CTD_human
TgeneESR1C0750936Intracranial Astrocytoma1CTD_human
TgeneESR1C0917730Female sterility1CTD_human
TgeneESR1C1563937Atherogenesis1CTD_human
TgeneESR1C1704230Grade I Astrocytoma1CTD_human
TgeneESR1C1704377Bright Disease1CTD_human
TgeneESR1C1720887Female Urogenital Diseases1CTD_human
TgeneESR1C1800706Idiopathic Pulmonary Fibrosis1CTD_human
TgeneESR1C4721508Hamman-Rich Disease1CTD_human
TgeneESR1C4721509Usual Interstitial Pneumonia1CTD_human
TgeneESR1C4721952Familial Idiopathic Pulmonary Fibrosis1CTD_human