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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:HDDC2-FAM47E (FusionGDB2 ID:35756)

Fusion Gene Summary for HDDC2-FAM47E

check button Fusion gene summary
Fusion gene informationFusion gene name: HDDC2-FAM47E
Fusion gene ID: 35756
HgeneTgene
Gene symbol

HDDC2

FAM47E

Gene ID

51020

100631383

Gene nameHD domain containing 2FAM47E-STBD1 readthrough
SynonymsC6orf74|CGI-130|NS5ATP2|dJ167O5.2FAM47E
Cytomap

6q22.31

4q21.1

Type of geneprotein-codingprotein-coding
DescriptionHD domain-containing protein 2HCV NS5A-transactivated protein 2hepatitis C virus NS5A-transactivated protein 2testicular tissue protein Li 83uncharacterized protein LOC100631383Protein FAM47E
Modification date2020031320200313
UniProtAcc

Q7Z4H3

Q6ZV65

Ensembl transtripts involved in fusion geneENST00000608456, ENST00000368377, 
ENST00000608295, ENST00000398153, 
ENST00000608284, 		ENST00000510197, 
ENST00000339906, ENST00000515604, 
ENST00000424749, ENST00000515589, 
Fusion gene scores* DoF score4 X 6 X 3=722 X 3 X 4=24
# samples 54
** MAII scorelog2(5/72*10)=-0.526068811667588
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: HDDC2 [Title/Abstract] AND FAM47E [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointHDDC2(125613987)-FAM47E(77184857), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across HDDC2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across FAM47E (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AR-A5QQ-01AHDDC2chr6

125613987

-FAM47Echr4

77184857

+
ChimerDB4BRCATCGA-AR-A5QQ-01AHDDC2chr6

125613987

-FAM47Echr4

77184857

+


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Fusion Gene ORF analysis for HDDC2-FAM47E

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000608456ENST00000510197HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-3CDSENST00000608456ENST00000339906HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-3CDSENST00000608456ENST00000515604HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-3CDSENST00000608456ENST00000424749HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-intronENST00000608456ENST00000515589HDDC2chr6

125613987

-FAM47Echr4

77184857

+
In-frameENST00000368377ENST00000510197HDDC2chr6

125613987

-FAM47Echr4

77184857

+
In-frameENST00000368377ENST00000339906HDDC2chr6

125613987

-FAM47Echr4

77184857

+
In-frameENST00000368377ENST00000515604HDDC2chr6

125613987

-FAM47Echr4

77184857

+
In-frameENST00000368377ENST00000424749HDDC2chr6

125613987

-FAM47Echr4

77184857

+
5CDS-intronENST00000368377ENST00000515589HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-3CDSENST00000608295ENST00000510197HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-3CDSENST00000608295ENST00000339906HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-3CDSENST00000608295ENST00000515604HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-3CDSENST00000608295ENST00000424749HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-intronENST00000608295ENST00000515589HDDC2chr6

125613987

-FAM47Echr4

77184857

+
In-frameENST00000398153ENST00000510197HDDC2chr6

125613987

-FAM47Echr4

77184857

+
In-frameENST00000398153ENST00000339906HDDC2chr6

125613987

-FAM47Echr4

77184857

+
In-frameENST00000398153ENST00000515604HDDC2chr6

125613987

-FAM47Echr4

77184857

+
In-frameENST00000398153ENST00000424749HDDC2chr6

125613987

-FAM47Echr4

77184857

+
5CDS-intronENST00000398153ENST00000515589HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-3CDSENST00000608284ENST00000510197HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-3CDSENST00000608284ENST00000339906HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-3CDSENST00000608284ENST00000515604HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-3CDSENST00000608284ENST00000424749HDDC2chr6

125613987

-FAM47Echr4

77184857

+
intron-intronENST00000608284ENST00000515589HDDC2chr6

125613987

-FAM47Echr4

77184857

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000368377HDDC2chr6125613987-ENST00000510197FAM47Echr477184857+16094801741286370
ENST00000368377HDDC2chr6125613987-ENST00000339906FAM47Echr477184857+15974801741286370
ENST00000368377HDDC2chr6125613987-ENST00000515604FAM47Echr477184857+30634801741115313
ENST00000368377HDDC2chr6125613987-ENST00000424749FAM47Echr477184857+15384801741241355
ENST00000398153HDDC2chr6125613987-ENST00000510197FAM47Echr477184857+1550421131227404
ENST00000398153HDDC2chr6125613987-ENST00000339906FAM47Echr477184857+1538421131227404
ENST00000398153HDDC2chr6125613987-ENST00000515604FAM47Echr477184857+3004421131056347
ENST00000398153HDDC2chr6125613987-ENST00000424749FAM47Echr477184857+1479421131182389

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000368377ENST00000510197HDDC2chr6125613987-FAM47Echr477184857+0.0004343210.99956566
ENST00000368377ENST00000339906HDDC2chr6125613987-FAM47Echr477184857+0.0004497680.99955016
ENST00000368377ENST00000515604HDDC2chr6125613987-FAM47Echr477184857+0.0003275450.9996724
ENST00000368377ENST00000424749HDDC2chr6125613987-FAM47Echr477184857+0.0005418930.99945813
ENST00000398153ENST00000510197HDDC2chr6125613987-FAM47Echr477184857+0.000622350.99937767
ENST00000398153ENST00000339906HDDC2chr6125613987-FAM47Echr477184857+0.0006692330.99933076
ENST00000398153ENST00000515604HDDC2chr6125613987-FAM47Echr477184857+0.000504930.999495
ENST00000398153ENST00000424749HDDC2chr6125613987-FAM47Echr477184857+0.0008843060.99911565

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Fusion Genomic Features for HDDC2-FAM47E


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
HDDC2chr6125613986-FAM47Echr477184856+0.0002705750.99972945
HDDC2chr6125613986-FAM47Echr477184856+0.0002705750.99972945

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for HDDC2-FAM47E


check button Go to

FGviewer for the breakpoints of chr6:125613987-chr4:77184857

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
HDDC2

Q7Z4H3

FAM47E

Q6ZV65

FUNCTION: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP). {ECO:0000250|UniProtKB:P53144}.FUNCTION: Promotes histone methylation by localizing the arginine methyltransferase PRMT5 to chromatin. {ECO:0000269|PubMed:33376131}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFAM47Echr6:125613987chr4:77184857ENST0000033990607326_35427.0296.0Coiled coilOntology_term=ECO:0000255
TgeneFAM47Echr6:125613987chr4:77184857ENST0000042474918326_354140.0394.0Coiled coilOntology_term=ECO:0000255
TgeneFAM47Echr6:125613987chr4:77184857ENST0000051019718326_35427.0296.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHDDC2chr6:125613987chr4:77184857ENST00000368377-4646_14892.0171.0DomainHD
HgeneHDDC2chr6:125613987chr4:77184857ENST00000398153-4646_148126.0205.0DomainHD


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Fusion Gene Sequence for HDDC2-FAM47E


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000368377_ENST00000510197_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(transcript)=1609nt_BP=480nt
GAAGTGGGGGAGGAGGAGGAGGAGTTGGAAGGGGAGGAGGAAGAGGGGGAGCAGGAAGAGGGGCAGAAGGAAGAAGAAGAGGGGGAGGAG
AAAGAGATAGAAGAGTAAGAGGAGGGGGAAGAAAGACAAGGGGAAGGGGAGGAGGAGGAGGACGGGGAGGAGCTTCGCCGCGGCCTGCTC
CGCCCAGCCGGGGTCGGTGGCCGCATGGCTTCGGTCTCCTCTGCGACCTTCTCGGGCCACGGGGCTCGGTCCCTACTGCAGTTCCTGCGG
CTGGTAGGGCAGCTCAAGAGAGTCCCACGAACTGGCTGGGTATACAGAAATGTCCAGAGGCCGGAGAGCGTTTCAGATCACATGTACCGG
ATGGCAGTTATGGCTATGGTGATCAAAGATGACCGTCTTAACAAAGACCGAGAAGCTATGAAGCAGATAACCCAGCTCCTACCAGAGGAC
CTCAGAAAGGAGCTCTATGAACTTTGGGAACTCTTATCAAAGGTGCTGGAAGTGCTTGATCCTGACCGGAAGCTGGAGGACACATGGGCT
TATTGTCAGGACACCAGGAAAGGAATGAAGGAACCCACGAAGCTTTTAAAAAAACATTCTACCCAAGTCTACCTGGGACCTTCCAAGAAG
ACGTCTGTGTCAAACGCAGGCCAATGGCTTTATGAAGAAAAGCCACATAAAATGGATTTGCTCCATGAAAATGGTCCTCGTCCTGGTCTT
CATGAAAATGTATGCAAAGCAGTTAGTGACTTCTGCAAGTGGGTTACTACTTTTGGAATTTCGGACATCGATGAAGAGTTCATCTTGAAA
CAGTTTGACATTGACTATGAGACCAAACCAAGCCATGATGCGCTCCACACGATGAAGCTAAATCAGGTTCCTCTGGAGCTAAAGCGTAGT
GTGGGGCTCAGTAAACTGCAGGAGACAGAGTTCTTCCAGAAACTAGGCTATGAGAGGAAACTCCAGAAACCACAGAATCCTTATAAGCCA
AAGTGGGTGAAGATGAGGTATGGAGCATGGTATTTGAACCCCAAGTTGTGGAAAAAGCAAAGAGTAGACGAGCCTCTGGTTGACCCTGAG
GTCTCACATAAGGCTCAAGAGGAGAATTTTAAAAAGGAGCTGCAGGAACAGGAGGAGTTACTTGCAGACCTTCACGGAACAGTTGCCTTT
AAGGATTTCATTCTAAGCAGGGGCTACAGGACGCCACGTTTCCTTGAGAATATGTATATCGGGAAGGAATGTAAACGTGCATGTAATAAG
ACTCCTATAAAACGAACTCAAGCATAGAAGAATCGTAGGAGAATGATTAGGCAGATTTTATTACTACGTACTTGGCTATTTCTCTGTCTC
CTTTTAAAGATTAAACAGAGTTTATGATGAGTGTCCCACTGTGGATGTTCAACTTTGACTTGGCAACATCTGTAAATGTAATACCTGATG
GTTATAAGCATTTCTCAATGGATTTCTGCTTCAGTTAATCAACATTTTGTATACTTTATCACCCATGAGATCAATATTCACATGTAATCT

>In-frame_ENST00000368377_ENST00000510197_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(amino acids)=370AA_start in transcript=174_stop in transcript=1286
MLRPAGVGGRMASVSSATFSGHGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDDRLNKDREAMKQITQLLP
EDLRKELYELWELLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTKLLKKHSTQVYLGPSKKTSVSNAGQWLYEEKPHKMDLLHENGPRP
GLHENVCKAVSDFCKWVTTFGISDIDEEFILKQFDIDYETKPSHDALHTMKLNQVPLELKRSVGLSKLQETEFFQKLGYERKLQKPQNPY
KPKWVKMRYGAWYLNPKLWKKQRVDEPLVDPEVSHKAQEENFKKELQEQEELLADLHGTVAFKDFILSRGYRTPRFLENMYIGKECKRAC

--------------------------------------------------------------
>In-frame_ENST00000368377_ENST00000339906_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(transcript)=1597nt_BP=480nt
GAAGTGGGGGAGGAGGAGGAGGAGTTGGAAGGGGAGGAGGAAGAGGGGGAGCAGGAAGAGGGGCAGAAGGAAGAAGAAGAGGGGGAGGAG
AAAGAGATAGAAGAGTAAGAGGAGGGGGAAGAAAGACAAGGGGAAGGGGAGGAGGAGGAGGACGGGGAGGAGCTTCGCCGCGGCCTGCTC
CGCCCAGCCGGGGTCGGTGGCCGCATGGCTTCGGTCTCCTCTGCGACCTTCTCGGGCCACGGGGCTCGGTCCCTACTGCAGTTCCTGCGG
CTGGTAGGGCAGCTCAAGAGAGTCCCACGAACTGGCTGGGTATACAGAAATGTCCAGAGGCCGGAGAGCGTTTCAGATCACATGTACCGG
ATGGCAGTTATGGCTATGGTGATCAAAGATGACCGTCTTAACAAAGACCGAGAAGCTATGAAGCAGATAACCCAGCTCCTACCAGAGGAC
CTCAGAAAGGAGCTCTATGAACTTTGGGAACTCTTATCAAAGGTGCTGGAAGTGCTTGATCCTGACCGGAAGCTGGAGGACACATGGGCT
TATTGTCAGGACACCAGGAAAGGAATGAAGGAACCCACGAAGCTTTTAAAAAAACATTCTACCCAAGTCTACCTGGGACCTTCCAAGAAG
ACGTCTGTGTCAAACGCAGGCCAATGGCTTTATGAAGAAAAGCCACATAAAATGGATTTGCTCCATGAAAATGGTCCTCGTCCTGGTCTT
CATGAAAATGTATGCAAAGCAGTTAGTGACTTCTGCAAGTGGGTTACTACTTTTGGAATTTCGGACATCGATGAAGAGTTCATCTTGAAA
CAGTTTGACATTGACTATGAGACCAAACCAAGCCATGATGCGCTCCACACGATGAAGCTAAATCAGGTTCCTCTGGAGCTAAAGCGTAGT
GTGGGGCTCAGTAAACTGCAGGAGACAGAGTTCTTCCAGAAACTAGGCTATGAGAGGAAACTCCAGAAACCACAGAATCCTTATAAGCCA
AAGTGGGTGAAGATGAGGTATGGAGCATGGTATTTGAACCCCAAGTTGTGGAAAAAGCAAAGAGTAGACGAGCCTCTGGTTGACCCTGAG
GTCTCACATAAGGCTCAAGAGGAGAATTTTAAAAAGGAGCTGCAGGAACAGGAGGAGTTACTTGCAGACCTTCACGGAACAGTTGCCTTT
AAGGATTTCATTCTAAGCAGGGGCTACAGGACGCCACGTTTCCTTGAGAATATGTATATCGGGAAGGAATGTAAACGTGCATGTAATAAG
ACTCCTATAAAACGAACTCAAGCATAGAAGAATCGTAGGAGAATGATTAGGCAGATTTTATTACTACGTACTTGGCTATTTCTCTGTCTC
CTTTTAAAGATTAAACAGAGTTTATGATGAGTGTCCCACTGTGGATGTTCAACTTTGACTTGGCAACATCTGTAAATGTAATACCTGATG
GTTATAAGCATTTCTCAATGGATTTCTGCTTCAGTTAATCAACATTTTGTATACTTTATCACCCATGAGATCAATATTCACATGTAATCT

>In-frame_ENST00000368377_ENST00000339906_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(amino acids)=370AA_start in transcript=174_stop in transcript=1286
MLRPAGVGGRMASVSSATFSGHGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDDRLNKDREAMKQITQLLP
EDLRKELYELWELLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTKLLKKHSTQVYLGPSKKTSVSNAGQWLYEEKPHKMDLLHENGPRP
GLHENVCKAVSDFCKWVTTFGISDIDEEFILKQFDIDYETKPSHDALHTMKLNQVPLELKRSVGLSKLQETEFFQKLGYERKLQKPQNPY
KPKWVKMRYGAWYLNPKLWKKQRVDEPLVDPEVSHKAQEENFKKELQEQEELLADLHGTVAFKDFILSRGYRTPRFLENMYIGKECKRAC

--------------------------------------------------------------
>In-frame_ENST00000368377_ENST00000515604_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(transcript)=3063nt_BP=480nt
GAAGTGGGGGAGGAGGAGGAGGAGTTGGAAGGGGAGGAGGAAGAGGGGGAGCAGGAAGAGGGGCAGAAGGAAGAAGAAGAGGGGGAGGAG
AAAGAGATAGAAGAGTAAGAGGAGGGGGAAGAAAGACAAGGGGAAGGGGAGGAGGAGGAGGACGGGGAGGAGCTTCGCCGCGGCCTGCTC
CGCCCAGCCGGGGTCGGTGGCCGCATGGCTTCGGTCTCCTCTGCGACCTTCTCGGGCCACGGGGCTCGGTCCCTACTGCAGTTCCTGCGG
CTGGTAGGGCAGCTCAAGAGAGTCCCACGAACTGGCTGGGTATACAGAAATGTCCAGAGGCCGGAGAGCGTTTCAGATCACATGTACCGG
ATGGCAGTTATGGCTATGGTGATCAAAGATGACCGTCTTAACAAAGACCGAGAAGCTATGAAGCAGATAACCCAGCTCCTACCAGAGGAC
CTCAGAAAGGAGCTCTATGAACTTTGGGAACTCTTATCAAAGGTGCTGGAAGTGCTTGATCCTGACCGGAAGCTGGAGGACACATGGGCT
TATTGTCAGGACACCAGGAAAGGAATGAAGGAACCCACGAAGCTTTTAAAAAAACATTCTACCCAAGTCTACCTGGGACCTTCCAAGAAG
ACGTCTGTGTCAAACGCAGGCCAATGGCTTTATGAAGAAAAGCCACATAAAATGGATTTGCTCCATGAAAATGGTCCTCGTCCTGGTCTT
CATGAAAATGGAATTTCGGACATCGATGAAGAGTTCATCTTGAAACAGTTTGACATTGACTATGAGACCAAACCAAGCCATGATGCGCTC
CACACGATGAAGCTAAATCAGGTTCCTCTGGAGCTAAAGCGTAGTGTGGGGCTCAGTAAACTGCAGGAGACAGAGTTCTTCCAGAAACTA
GGCTATGAGAGGAAACTCCAGAAACCACAGAATCCTTATAAGCCAAAGTGGGTGAAGATGAGGTATGGAGCATGGTATTTGAACCCCAAG
TTGTGGAAAAAGCAAAGAGTAGACGAGCCTCTGGTTGACCCTGAGGTCTCACATAAGGCTCAAGAGGAGAATTTTAAAAAGGAGCTGCAG
GAACAGAGCATCTTCAAGAAAGCAATGGACATTTGATTTCTAAGACCAAAGACCTTGGTAAACTGCAAGCAGCATCATGGAGATTGCAGA
ATCCTTCCAGGGAAGTCTGTGACAATTCAAGAGAACATGTTCCTTCTGGACAGTTTCCAGACACAGAAGCTCCAGCTACCTCTGAGACCA
GTAACTCTAGGAGTTACTCTGAAGTTTCAAGAAATGAAAGCCTTGAATCTCCTATGGGAGAATGGGGATTCCAAAAAGGACAAGAGATAT
CTGCTAAAGCAGCTACATGTTTTGCAGAGAAGTTGCCTTCTAGCAACCTGCTCAAGAACAGAGCTAAAGAAGAAATGAGCCTCTCTGATT
TGAACAGTCAGGACCGGGTTGACCACGAGGAGTGGGAAATGGTGCCTAGGCACTCATCTTGGGGGGATGTTGGTGTGGGTGGCAGTCTTA
AGGCTCCAGTGTTAAACCTAAACCAGGGAATGGACAATGGAAGAAGCACTTTGGTGGAAGCAAGAGGTCAGCAAGTGCATGGGAAAATGG
AAAGGGTAGCAGTGATGCCTGCAGGGTCTCAGCAAGTTAGTGTCAGGTTCCAGGTCCATTATGTCACAAGCACTGATGTGCAATTCATTG
CAGTAACTGGAGACCATGAGTGTCTTGGGAGATGGAACACTTACATCCCACTCCACTATAACAAGGATGGGTTCTGGTCTCATTCCATTT
TCCTGCCTGCAGATACAGTGGTGGAGTGGAAGTTTGTGTTGGTAGAGAATGGGGGAGTTACCCGCTGGGAAGAATGCAGCAATAGATTCC
TAGAAACTGGCCATGAGGATAAAGTGGTTCACGCATGGTGGGGGATTCACTGATTCAGTTTGCAAAGTAATGGAGAAGCTGTAGAACAAT
GTGGAAGAGGCTGAGGTTGTGGAACACACTGAATAAAATAAAGGCAGTGTGACTCCAAATTCAGCCATCTGAATTGTTTAAATTTGCTAG
TGGATTTTGTCTAATGTGCAGAAATATATATGTCTAATGTGCAGAAATATATATGTGTGTATGTGTGTATATATATGCACACACACACAG
ATAATGCTTCCAGTGAATGTGAACTTCTTTTCCCTGTGGCACTGATTGACAGACTTGTGCTGATCCATTATTACTTTAGGGCTTGATTCT
CTTGGGGAGTGACTTGGCTAAGCTTCAGGTGTAAACTGTGGTCACGGAGCAAAAACATTAACCAGCTGCCCAGGGTTCAAGCTTGAGCCT
TTAGGTGATCTTTAAACTATGGTAGTAAAATAAGCCTCACTCAAACATAGCTGACTTCCTATTGGTACAGCTTGAAAAGCACTTTTTACT
ACATACACATTTTATGCTTAAAAAGTTAACATGATACGAAACTGTGATTAGAAAATATCTGGTCTGGATGTGATTAGTAAGGATACAAGA
TAATGTTCTAAGACTGCCTAATGCTTTTTGTTTGATTTTCATCTGCCAGGCGTTGTTATGTGCTATGAGGGTAGCAAGTACGTCTTTGTC
TTAATGATCTAAGGCTGGTGTAGAAACAAAGGGCCTAATGAGAACCAATCATCATGGAAGTCAGTTGCGGGGGCAGCCCATAAGGAAAGG
GAAAGTGAGTGGGGTTGGGCATAGGCTGAGTGAGGTGGCCTGAATGACACCTCTTAGAGGACTGTGAAGTACAGGCACAGCCCGACTGCA
GGGAGGGATGCACCCATCATTTACCCATGGGAGCATCTGTAGGACCATCTCTCTCCCACTTCTTCTCCCCTCCCCCACCGCATCTGGCCA
GATGGACTGTCCTACAGCAATCGTTTCCATCTGTCACCCTCTTCCCTCTCCTTTCATACCAGTCACTATCTTGGGTAACAAATTTATACA
GGACAGTGGTACAGAAATACATCTTTGCTCTGAGAATACAGCAAATATTAACTTAAATTATTATAACTGAACAAATAATAAAACCTGAAT

>In-frame_ENST00000368377_ENST00000515604_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(amino acids)=313AA_start in transcript=174_stop in transcript=1115
MLRPAGVGGRMASVSSATFSGHGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDDRLNKDREAMKQITQLLP
EDLRKELYELWELLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTKLLKKHSTQVYLGPSKKTSVSNAGQWLYEEKPHKMDLLHENGPRP
GLHENGISDIDEEFILKQFDIDYETKPSHDALHTMKLNQVPLELKRSVGLSKLQETEFFQKLGYERKLQKPQNPYKPKWVKMRYGAWYLN

--------------------------------------------------------------
>In-frame_ENST00000368377_ENST00000424749_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(transcript)=1538nt_BP=480nt
GAAGTGGGGGAGGAGGAGGAGGAGTTGGAAGGGGAGGAGGAAGAGGGGGAGCAGGAAGAGGGGCAGAAGGAAGAAGAAGAGGGGGAGGAG
AAAGAGATAGAAGAGTAAGAGGAGGGGGAAGAAAGACAAGGGGAAGGGGAGGAGGAGGAGGACGGGGAGGAGCTTCGCCGCGGCCTGCTC
CGCCCAGCCGGGGTCGGTGGCCGCATGGCTTCGGTCTCCTCTGCGACCTTCTCGGGCCACGGGGCTCGGTCCCTACTGCAGTTCCTGCGG
CTGGTAGGGCAGCTCAAGAGAGTCCCACGAACTGGCTGGGTATACAGAAATGTCCAGAGGCCGGAGAGCGTTTCAGATCACATGTACCGG
ATGGCAGTTATGGCTATGGTGATCAAAGATGACCGTCTTAACAAAGACCGAGAAGCTATGAAGCAGATAACCCAGCTCCTACCAGAGGAC
CTCAGAAAGGAGCTCTATGAACTTTGGGAACTCTTATCAAAGGTGCTGGAAGTGCTTGATCCTGACCGGAAGCTGGAGGACACATGGGCT
TATTGTCAGGACACCAGGAAAGGAATGAAGGAACCCACGAAGCTTTTAAAAAAACATTCTACCCAAGTCTACCTGGGACCTTCCAAGAAG
ACGTCTGTGTCAAACGCAGGCCAATGGCTTTATGAAGAAAAGCCACATAAAATGGATTTGCTCCATGAAAATGGTCCTCGTCCTGGTCTT
CATGAAAATGGAATTTCGGACATCGATGAAGAGTTCATCTTGAAACAGTTTGACATTGACTATGAGACCAAACCAAGCCATGATGCGCTC
CACACGATGAAGCTAAATCAGGTTCCTCTGGAGCTAAAGCGTAGTGTGGGGCTCAGTAAACTGCAGGAGACAGAGTTCTTCCAGAAACTA
GGCTATGAGAGGAAACTCCAGAAACCACAGAATCCTTATAAGCCAAAGTGGGTGAAGATGAGGTATGGAGCATGGTATTTGAACCCCAAG
TTGTGGAAAAAGCAAAGAGTAGACGAGCCTCTGGTTGACCCTGAGGTCTCACATAAGGCTCAAGAGGAGAATTTTAAAAAGGAGCTGCAG
GAACAGGAGGAGTTACTTGCAGACCTTCACGGAACAGTTGCCTTTAAGGATTTCATTCTAAGCAGGGGCTACAGGACGCCACGTTTCCTT
GAGAATATGTATATCGGGAAGGAATGTAAACGTGCATGTAATAAGACTCCTATAAAACGAACTCAAGCATAGAAGAATCGTAGGAGAATG
ATTAGGCAGATTTTATTACTACGTACTTGGCTATTTCTCTGTCTCCTTTTAAAGATTAAACAGAGTTTATGATGAGTGTCCCACTGTGGA
TGTTCAACTTTGACTTGGCAACATCTGTAAATGTAATACCTGATGGTTATAAGCATTTCTCAATGGATTTCTGCTTCAGTTAATCAACAT
TTTGTATACTTTATCACCCATGAGATCAATATTCACATGTAATCTTCTCATATTTTTGTGGCACGTGAATATTATATAGGTATATCAACT

>In-frame_ENST00000368377_ENST00000424749_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(amino acids)=355AA_start in transcript=174_stop in transcript=1241
MLRPAGVGGRMASVSSATFSGHGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDDRLNKDREAMKQITQLLP
EDLRKELYELWELLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTKLLKKHSTQVYLGPSKKTSVSNAGQWLYEEKPHKMDLLHENGPRP
GLHENGISDIDEEFILKQFDIDYETKPSHDALHTMKLNQVPLELKRSVGLSKLQETEFFQKLGYERKLQKPQNPYKPKWVKMRYGAWYLN

--------------------------------------------------------------
>In-frame_ENST00000398153_ENST00000510197_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(transcript)=1550nt_BP=421nt
GCTTCGCCGCGGCCTGCTCCGCCCAGCCGGGGTCGGTGGCCGCATGGCTTCGGTCTCCTCTGCGACCTTCTCGGGCCACGGGGCTCGGTC
CCTACTGCAGTTCCTGCGGCTGGTAGGGCAGCTCAAGAGAGTCCCACGAACTGGCTGGGTATACAGAAATGTCCAGAGGCCGGAGAGCGT
TTCAGATCACATGTACCGGATGGCAGTTATGGCTATGGTGATCAAAGATGACCGTCTTAACAAAGACCGATGTGTACGCCTAGCCCTGGT
TCATGATATGGCAGAATGCATCGTTGGGGACATAGCACCAGCAGATAACATCCCCAAAGAAGAAAAACATAGGCGAGAAGAGGAAGCTAT
GAAGCAGATAACCCAGCTCCTACCAGAGGACCTCAGAAAGGAGCTCTATGAACTTTGGGAACTCTTATCAAAGGTGCTGGAAGTGCTTGA
TCCTGACCGGAAGCTGGAGGACACATGGGCTTATTGTCAGGACACCAGGAAAGGAATGAAGGAACCCACGAAGCTTTTAAAAAAACATTC
TACCCAAGTCTACCTGGGACCTTCCAAGAAGACGTCTGTGTCAAACGCAGGCCAATGGCTTTATGAAGAAAAGCCACATAAAATGGATTT
GCTCCATGAAAATGGTCCTCGTCCTGGTCTTCATGAAAATGTATGCAAAGCAGTTAGTGACTTCTGCAAGTGGGTTACTACTTTTGGAAT
TTCGGACATCGATGAAGAGTTCATCTTGAAACAGTTTGACATTGACTATGAGACCAAACCAAGCCATGATGCGCTCCACACGATGAAGCT
AAATCAGGTTCCTCTGGAGCTAAAGCGTAGTGTGGGGCTCAGTAAACTGCAGGAGACAGAGTTCTTCCAGAAACTAGGCTATGAGAGGAA
ACTCCAGAAACCACAGAATCCTTATAAGCCAAAGTGGGTGAAGATGAGGTATGGAGCATGGTATTTGAACCCCAAGTTGTGGAAAAAGCA
AAGAGTAGACGAGCCTCTGGTTGACCCTGAGGTCTCACATAAGGCTCAAGAGGAGAATTTTAAAAAGGAGCTGCAGGAACAGGAGGAGTT
ACTTGCAGACCTTCACGGAACAGTTGCCTTTAAGGATTTCATTCTAAGCAGGGGCTACAGGACGCCACGTTTCCTTGAGAATATGTATAT
CGGGAAGGAATGTAAACGTGCATGTAATAAGACTCCTATAAAACGAACTCAAGCATAGAAGAATCGTAGGAGAATGATTAGGCAGATTTT
ATTACTACGTACTTGGCTATTTCTCTGTCTCCTTTTAAAGATTAAACAGAGTTTATGATGAGTGTCCCACTGTGGATGTTCAACTTTGAC
TTGGCAACATCTGTAAATGTAATACCTGATGGTTATAAGCATTTCTCAATGGATTTCTGCTTCAGTTAATCAACATTTTGTATACTTTAT
CACCCATGAGATCAATATTCACATGTAATCTTCTCATATTTTTGTGGCACGTGAATATTATATAGGTATATCAACTATTGGTAAAAATAA

>In-frame_ENST00000398153_ENST00000510197_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(amino acids)=404AA_start in transcript=13_stop in transcript=1227
MLRPAGVGGRMASVSSATFSGHGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDDRLNKDRCVRLALVHDMA
ECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYELWELLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTKLLKKHSTQVY
LGPSKKTSVSNAGQWLYEEKPHKMDLLHENGPRPGLHENVCKAVSDFCKWVTTFGISDIDEEFILKQFDIDYETKPSHDALHTMKLNQVP
LELKRSVGLSKLQETEFFQKLGYERKLQKPQNPYKPKWVKMRYGAWYLNPKLWKKQRVDEPLVDPEVSHKAQEENFKKELQEQEELLADL

--------------------------------------------------------------
>In-frame_ENST00000398153_ENST00000339906_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(transcript)=1538nt_BP=421nt
GCTTCGCCGCGGCCTGCTCCGCCCAGCCGGGGTCGGTGGCCGCATGGCTTCGGTCTCCTCTGCGACCTTCTCGGGCCACGGGGCTCGGTC
CCTACTGCAGTTCCTGCGGCTGGTAGGGCAGCTCAAGAGAGTCCCACGAACTGGCTGGGTATACAGAAATGTCCAGAGGCCGGAGAGCGT
TTCAGATCACATGTACCGGATGGCAGTTATGGCTATGGTGATCAAAGATGACCGTCTTAACAAAGACCGATGTGTACGCCTAGCCCTGGT
TCATGATATGGCAGAATGCATCGTTGGGGACATAGCACCAGCAGATAACATCCCCAAAGAAGAAAAACATAGGCGAGAAGAGGAAGCTAT
GAAGCAGATAACCCAGCTCCTACCAGAGGACCTCAGAAAGGAGCTCTATGAACTTTGGGAACTCTTATCAAAGGTGCTGGAAGTGCTTGA
TCCTGACCGGAAGCTGGAGGACACATGGGCTTATTGTCAGGACACCAGGAAAGGAATGAAGGAACCCACGAAGCTTTTAAAAAAACATTC
TACCCAAGTCTACCTGGGACCTTCCAAGAAGACGTCTGTGTCAAACGCAGGCCAATGGCTTTATGAAGAAAAGCCACATAAAATGGATTT
GCTCCATGAAAATGGTCCTCGTCCTGGTCTTCATGAAAATGTATGCAAAGCAGTTAGTGACTTCTGCAAGTGGGTTACTACTTTTGGAAT
TTCGGACATCGATGAAGAGTTCATCTTGAAACAGTTTGACATTGACTATGAGACCAAACCAAGCCATGATGCGCTCCACACGATGAAGCT
AAATCAGGTTCCTCTGGAGCTAAAGCGTAGTGTGGGGCTCAGTAAACTGCAGGAGACAGAGTTCTTCCAGAAACTAGGCTATGAGAGGAA
ACTCCAGAAACCACAGAATCCTTATAAGCCAAAGTGGGTGAAGATGAGGTATGGAGCATGGTATTTGAACCCCAAGTTGTGGAAAAAGCA
AAGAGTAGACGAGCCTCTGGTTGACCCTGAGGTCTCACATAAGGCTCAAGAGGAGAATTTTAAAAAGGAGCTGCAGGAACAGGAGGAGTT
ACTTGCAGACCTTCACGGAACAGTTGCCTTTAAGGATTTCATTCTAAGCAGGGGCTACAGGACGCCACGTTTCCTTGAGAATATGTATAT
CGGGAAGGAATGTAAACGTGCATGTAATAAGACTCCTATAAAACGAACTCAAGCATAGAAGAATCGTAGGAGAATGATTAGGCAGATTTT
ATTACTACGTACTTGGCTATTTCTCTGTCTCCTTTTAAAGATTAAACAGAGTTTATGATGAGTGTCCCACTGTGGATGTTCAACTTTGAC
TTGGCAACATCTGTAAATGTAATACCTGATGGTTATAAGCATTTCTCAATGGATTTCTGCTTCAGTTAATCAACATTTTGTATACTTTAT
CACCCATGAGATCAATATTCACATGTAATCTTCTCATATTTTTGTGGCACGTGAATATTATATAGGTATATCAACTATTGGTAAAAATAA

>In-frame_ENST00000398153_ENST00000339906_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(amino acids)=404AA_start in transcript=13_stop in transcript=1227
MLRPAGVGGRMASVSSATFSGHGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDDRLNKDRCVRLALVHDMA
ECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYELWELLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTKLLKKHSTQVY
LGPSKKTSVSNAGQWLYEEKPHKMDLLHENGPRPGLHENVCKAVSDFCKWVTTFGISDIDEEFILKQFDIDYETKPSHDALHTMKLNQVP
LELKRSVGLSKLQETEFFQKLGYERKLQKPQNPYKPKWVKMRYGAWYLNPKLWKKQRVDEPLVDPEVSHKAQEENFKKELQEQEELLADL

--------------------------------------------------------------
>In-frame_ENST00000398153_ENST00000515604_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(transcript)=3004nt_BP=421nt
GCTTCGCCGCGGCCTGCTCCGCCCAGCCGGGGTCGGTGGCCGCATGGCTTCGGTCTCCTCTGCGACCTTCTCGGGCCACGGGGCTCGGTC
CCTACTGCAGTTCCTGCGGCTGGTAGGGCAGCTCAAGAGAGTCCCACGAACTGGCTGGGTATACAGAAATGTCCAGAGGCCGGAGAGCGT
TTCAGATCACATGTACCGGATGGCAGTTATGGCTATGGTGATCAAAGATGACCGTCTTAACAAAGACCGATGTGTACGCCTAGCCCTGGT
TCATGATATGGCAGAATGCATCGTTGGGGACATAGCACCAGCAGATAACATCCCCAAAGAAGAAAAACATAGGCGAGAAGAGGAAGCTAT
GAAGCAGATAACCCAGCTCCTACCAGAGGACCTCAGAAAGGAGCTCTATGAACTTTGGGAACTCTTATCAAAGGTGCTGGAAGTGCTTGA
TCCTGACCGGAAGCTGGAGGACACATGGGCTTATTGTCAGGACACCAGGAAAGGAATGAAGGAACCCACGAAGCTTTTAAAAAAACATTC
TACCCAAGTCTACCTGGGACCTTCCAAGAAGACGTCTGTGTCAAACGCAGGCCAATGGCTTTATGAAGAAAAGCCACATAAAATGGATTT
GCTCCATGAAAATGGTCCTCGTCCTGGTCTTCATGAAAATGGAATTTCGGACATCGATGAAGAGTTCATCTTGAAACAGTTTGACATTGA
CTATGAGACCAAACCAAGCCATGATGCGCTCCACACGATGAAGCTAAATCAGGTTCCTCTGGAGCTAAAGCGTAGTGTGGGGCTCAGTAA
ACTGCAGGAGACAGAGTTCTTCCAGAAACTAGGCTATGAGAGGAAACTCCAGAAACCACAGAATCCTTATAAGCCAAAGTGGGTGAAGAT
GAGGTATGGAGCATGGTATTTGAACCCCAAGTTGTGGAAAAAGCAAAGAGTAGACGAGCCTCTGGTTGACCCTGAGGTCTCACATAAGGC
TCAAGAGGAGAATTTTAAAAAGGAGCTGCAGGAACAGAGCATCTTCAAGAAAGCAATGGACATTTGATTTCTAAGACCAAAGACCTTGGT
AAACTGCAAGCAGCATCATGGAGATTGCAGAATCCTTCCAGGGAAGTCTGTGACAATTCAAGAGAACATGTTCCTTCTGGACAGTTTCCA
GACACAGAAGCTCCAGCTACCTCTGAGACCAGTAACTCTAGGAGTTACTCTGAAGTTTCAAGAAATGAAAGCCTTGAATCTCCTATGGGA
GAATGGGGATTCCAAAAAGGACAAGAGATATCTGCTAAAGCAGCTACATGTTTTGCAGAGAAGTTGCCTTCTAGCAACCTGCTCAAGAAC
AGAGCTAAAGAAGAAATGAGCCTCTCTGATTTGAACAGTCAGGACCGGGTTGACCACGAGGAGTGGGAAATGGTGCCTAGGCACTCATCT
TGGGGGGATGTTGGTGTGGGTGGCAGTCTTAAGGCTCCAGTGTTAAACCTAAACCAGGGAATGGACAATGGAAGAAGCACTTTGGTGGAA
GCAAGAGGTCAGCAAGTGCATGGGAAAATGGAAAGGGTAGCAGTGATGCCTGCAGGGTCTCAGCAAGTTAGTGTCAGGTTCCAGGTCCAT
TATGTCACAAGCACTGATGTGCAATTCATTGCAGTAACTGGAGACCATGAGTGTCTTGGGAGATGGAACACTTACATCCCACTCCACTAT
AACAAGGATGGGTTCTGGTCTCATTCCATTTTCCTGCCTGCAGATACAGTGGTGGAGTGGAAGTTTGTGTTGGTAGAGAATGGGGGAGTT
ACCCGCTGGGAAGAATGCAGCAATAGATTCCTAGAAACTGGCCATGAGGATAAAGTGGTTCACGCATGGTGGGGGATTCACTGATTCAGT
TTGCAAAGTAATGGAGAAGCTGTAGAACAATGTGGAAGAGGCTGAGGTTGTGGAACACACTGAATAAAATAAAGGCAGTGTGACTCCAAA
TTCAGCCATCTGAATTGTTTAAATTTGCTAGTGGATTTTGTCTAATGTGCAGAAATATATATGTCTAATGTGCAGAAATATATATGTGTG
TATGTGTGTATATATATGCACACACACACAGATAATGCTTCCAGTGAATGTGAACTTCTTTTCCCTGTGGCACTGATTGACAGACTTGTG
CTGATCCATTATTACTTTAGGGCTTGATTCTCTTGGGGAGTGACTTGGCTAAGCTTCAGGTGTAAACTGTGGTCACGGAGCAAAAACATT
AACCAGCTGCCCAGGGTTCAAGCTTGAGCCTTTAGGTGATCTTTAAACTATGGTAGTAAAATAAGCCTCACTCAAACATAGCTGACTTCC
TATTGGTACAGCTTGAAAAGCACTTTTTACTACATACACATTTTATGCTTAAAAAGTTAACATGATACGAAACTGTGATTAGAAAATATC
TGGTCTGGATGTGATTAGTAAGGATACAAGATAATGTTCTAAGACTGCCTAATGCTTTTTGTTTGATTTTCATCTGCCAGGCGTTGTTAT
GTGCTATGAGGGTAGCAAGTACGTCTTTGTCTTAATGATCTAAGGCTGGTGTAGAAACAAAGGGCCTAATGAGAACCAATCATCATGGAA
GTCAGTTGCGGGGGCAGCCCATAAGGAAAGGGAAAGTGAGTGGGGTTGGGCATAGGCTGAGTGAGGTGGCCTGAATGACACCTCTTAGAG
GACTGTGAAGTACAGGCACAGCCCGACTGCAGGGAGGGATGCACCCATCATTTACCCATGGGAGCATCTGTAGGACCATCTCTCTCCCAC
TTCTTCTCCCCTCCCCCACCGCATCTGGCCAGATGGACTGTCCTACAGCAATCGTTTCCATCTGTCACCCTCTTCCCTCTCCTTTCATAC
CAGTCACTATCTTGGGTAACAAATTTATACAGGACAGTGGTACAGAAATACATCTTTGCTCTGAGAATACAGCAAATATTAACTTAAATT

>In-frame_ENST00000398153_ENST00000515604_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(amino acids)=347AA_start in transcript=13_stop in transcript=1056
MLRPAGVGGRMASVSSATFSGHGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDDRLNKDRCVRLALVHDMA
ECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYELWELLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTKLLKKHSTQVY
LGPSKKTSVSNAGQWLYEEKPHKMDLLHENGPRPGLHENGISDIDEEFILKQFDIDYETKPSHDALHTMKLNQVPLELKRSVGLSKLQET

--------------------------------------------------------------
>In-frame_ENST00000398153_ENST00000424749_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(transcript)=1479nt_BP=421nt
GCTTCGCCGCGGCCTGCTCCGCCCAGCCGGGGTCGGTGGCCGCATGGCTTCGGTCTCCTCTGCGACCTTCTCGGGCCACGGGGCTCGGTC
CCTACTGCAGTTCCTGCGGCTGGTAGGGCAGCTCAAGAGAGTCCCACGAACTGGCTGGGTATACAGAAATGTCCAGAGGCCGGAGAGCGT
TTCAGATCACATGTACCGGATGGCAGTTATGGCTATGGTGATCAAAGATGACCGTCTTAACAAAGACCGATGTGTACGCCTAGCCCTGGT
TCATGATATGGCAGAATGCATCGTTGGGGACATAGCACCAGCAGATAACATCCCCAAAGAAGAAAAACATAGGCGAGAAGAGGAAGCTAT
GAAGCAGATAACCCAGCTCCTACCAGAGGACCTCAGAAAGGAGCTCTATGAACTTTGGGAACTCTTATCAAAGGTGCTGGAAGTGCTTGA
TCCTGACCGGAAGCTGGAGGACACATGGGCTTATTGTCAGGACACCAGGAAAGGAATGAAGGAACCCACGAAGCTTTTAAAAAAACATTC
TACCCAAGTCTACCTGGGACCTTCCAAGAAGACGTCTGTGTCAAACGCAGGCCAATGGCTTTATGAAGAAAAGCCACATAAAATGGATTT
GCTCCATGAAAATGGTCCTCGTCCTGGTCTTCATGAAAATGGAATTTCGGACATCGATGAAGAGTTCATCTTGAAACAGTTTGACATTGA
CTATGAGACCAAACCAAGCCATGATGCGCTCCACACGATGAAGCTAAATCAGGTTCCTCTGGAGCTAAAGCGTAGTGTGGGGCTCAGTAA
ACTGCAGGAGACAGAGTTCTTCCAGAAACTAGGCTATGAGAGGAAACTCCAGAAACCACAGAATCCTTATAAGCCAAAGTGGGTGAAGAT
GAGGTATGGAGCATGGTATTTGAACCCCAAGTTGTGGAAAAAGCAAAGAGTAGACGAGCCTCTGGTTGACCCTGAGGTCTCACATAAGGC
TCAAGAGGAGAATTTTAAAAAGGAGCTGCAGGAACAGGAGGAGTTACTTGCAGACCTTCACGGAACAGTTGCCTTTAAGGATTTCATTCT
AAGCAGGGGCTACAGGACGCCACGTTTCCTTGAGAATATGTATATCGGGAAGGAATGTAAACGTGCATGTAATAAGACTCCTATAAAACG
AACTCAAGCATAGAAGAATCGTAGGAGAATGATTAGGCAGATTTTATTACTACGTACTTGGCTATTTCTCTGTCTCCTTTTAAAGATTAA
ACAGAGTTTATGATGAGTGTCCCACTGTGGATGTTCAACTTTGACTTGGCAACATCTGTAAATGTAATACCTGATGGTTATAAGCATTTC
TCAATGGATTTCTGCTTCAGTTAATCAACATTTTGTATACTTTATCACCCATGAGATCAATATTCACATGTAATCTTCTCATATTTTTGT

>In-frame_ENST00000398153_ENST00000424749_TCGA-AR-A5QQ-01A_HDDC2_chr6_125613987_-_FAM47E_chr4_77184857_length(amino acids)=389AA_start in transcript=13_stop in transcript=1182
MLRPAGVGGRMASVSSATFSGHGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDDRLNKDRCVRLALVHDMA
ECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYELWELLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTKLLKKHSTQVY
LGPSKKTSVSNAGQWLYEEKPHKMDLLHENGPRPGLHENGISDIDEEFILKQFDIDYETKPSHDALHTMKLNQVPLELKRSVGLSKLQET
EFFQKLGYERKLQKPQNPYKPKWVKMRYGAWYLNPKLWKKQRVDEPLVDPEVSHKAQEENFKKELQEQEELLADLHGTVAFKDFILSRGY

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Fusion Gene PPI Analysis for HDDC2-FAM47E


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for HDDC2-FAM47E


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for HDDC2-FAM47E


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource