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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:HIVEP1-SUCO (FusionGDB2 ID:36395) |
Fusion Gene Summary for HIVEP1-SUCO |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HIVEP1-SUCO | Fusion gene ID: 36395 | Hgene | Tgene | Gene symbol | HIVEP1 | SUCO | Gene ID | 3096 | 51430 |
| Gene name | HIVEP zinc finger 1 | SUN domain containing ossification factor | |
| Synonyms | CIRIP|CRYBP1|GAAP|MBP-1|PRDII-BF1|Schnurri-1|ZAS1|ZNF40|ZNF40A | C1orf9|CH1|OPT|SLP1 | |
| Cytomap | 6p24.1 | 1q24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger protein 40cirhin interaction proteingate keeper of apoptosis-activating proteinhuman immunodeficiency virus type I enhancer binding protein 1major histocompatibility complex binding protein 1positive regulatory domain II binding factor 1 | SUN domain-containing ossification factorSUN-like protein 1membrane protein CH1osteopotentia | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | P15822 | Q9UBS9 | |
| Ensembl transtripts involved in fusion gene | ENST00000379388, ENST00000484210, ENST00000541134, | ENST00000367723, ENST00000608151, ENST00000610051, ENST00000263688, | |
| Fusion gene scores | * DoF score | 12 X 8 X 8=768 | 5 X 6 X 3=90 |
| # samples | 14 | 5 | |
| ** MAII score | log2(14/768*10)=-2.45567948377619 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/90*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: HIVEP1 [Title/Abstract] AND SUCO [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | HIVEP1(12121904)-SUCO(172579038), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | HIVEP1-SUCO seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF. HIVEP1-SUCO seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF. HIVEP1-SUCO seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. HIVEP1-SUCO seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | HIVEP1 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 17008448 |
| Hgene | HIVEP1 | GO:0030509 | BMP signaling pathway | 17008448 |
| Hgene | HIVEP1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 17008448 |
| Fusion gene breakpoints across HIVEP1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across SUCO (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS5.0 | N/A | BE006447 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
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Fusion Gene ORF analysis for HIVEP1-SUCO |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000379388 | ENST00000367723 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| In-frame | ENST00000379388 | ENST00000608151 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| Frame-shift | ENST00000379388 | ENST00000610051 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| In-frame | ENST00000379388 | ENST00000263688 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| intron-3CDS | ENST00000484210 | ENST00000367723 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| intron-3CDS | ENST00000484210 | ENST00000608151 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| intron-3CDS | ENST00000484210 | ENST00000610051 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| intron-3CDS | ENST00000484210 | ENST00000263688 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| intron-3CDS | ENST00000541134 | ENST00000367723 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| intron-3CDS | ENST00000541134 | ENST00000608151 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| intron-3CDS | ENST00000541134 | ENST00000610051 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| intron-3CDS | ENST00000541134 | ENST00000263688 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000379388 | HIVEP1 | chr6 | 12121904 | - | ENST00000367723 | SUCO | chr1 | 172579038 | - | 6558 | 4625 | 332 | 4666 | 1444 |
| ENST00000379388 | HIVEP1 | chr6 | 12121904 | - | ENST00000608151 | SUCO | chr1 | 172579038 | - | 6558 | 4625 | 332 | 4666 | 1444 |
| ENST00000379388 | HIVEP1 | chr6 | 12121904 | - | ENST00000263688 | SUCO | chr1 | 172579038 | - | 6558 | 4625 | 332 | 4666 | 1444 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000379388 | ENST00000367723 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - | 0.000291632 | 0.99970835 |
| ENST00000379388 | ENST00000608151 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - | 0.000291632 | 0.99970835 |
| ENST00000379388 | ENST00000263688 | HIVEP1 | chr6 | 12121904 | - | SUCO | chr1 | 172579038 | - | 0.000291632 | 0.99970835 |
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Fusion Genomic Features for HIVEP1-SUCO |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for HIVEP1-SUCO |
| Go to FGviewer for the breakpoints of chr6:12121904-chr1:172579038 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HIVEP1 | SUCO |
| FUNCTION: This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis. | FUNCTION: Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | SUCO | chr6:12121904 | chr1:172579038 | ENST00000263688 | 0 | 24 | 909_1009 | 0 | 1255.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | SUCO | chr6:12121904 | chr1:172579038 | ENST00000263688 | 0 | 24 | 284_453 | 0 | 1255.0 | Domain | SUN | |
| Tgene | SUCO | chr6:12121904 | chr1:172579038 | ENST00000263688 | 0 | 24 | 1011_1031 | 0 | 1255.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | HIVEP1 | chr6:12121904 | chr1:172579038 | ENST00000379388 | - | 1 | 9 | 803_806 | 0 | 2719.0 | Compositional bias | Note=Poly-Ser |
| Hgene | HIVEP1 | chr6:12121904 | chr1:172579038 | ENST00000379388 | - | 1 | 9 | 2088_2110 | 0 | 2719.0 | Zinc finger | C2H2-type 3 |
| Hgene | HIVEP1 | chr6:12121904 | chr1:172579038 | ENST00000379388 | - | 1 | 9 | 2116_2140 | 0 | 2719.0 | Zinc finger | C2H2-type 4 |
| Hgene | HIVEP1 | chr6:12121904 | chr1:172579038 | ENST00000379388 | - | 1 | 9 | 406_428 | 0 | 2719.0 | Zinc finger | C2H2-type 1 |
| Hgene | HIVEP1 | chr6:12121904 | chr1:172579038 | ENST00000379388 | - | 1 | 9 | 434_456 | 0 | 2719.0 | Zinc finger | C2H2-type 2 |
| Hgene | HIVEP1 | chr6:12121904 | chr1:172579038 | ENST00000379388 | - | 1 | 9 | 956_986 | 0 | 2719.0 | Zinc finger | CCHC HIVEP-type |
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Fusion Gene Sequence for HIVEP1-SUCO |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000379388_ENST00000367723_BE006447_HIVEP1_chr6_12121904_-_SUCO_chr1_172579038_length(transcript)=6558nt_BP=4625nt GCTGCTGGGCGGCGGCAGGGTGGCGGACGGAGCGGGGGACCGGGGAGCGGCGGCCGCCGGAGGAGGTTATGTTTGTGTTTGGGGTTGTCA AGTGAAGGAGGGATCCCAGGCGCCGCCGCCGCCGCCGCGCGGGGGTCGCGGAGATCCCGAGCCGCGGCCGCCGCCATCAGCAGCGCAGCT CCAGGGCCGGCTGCAGCGGCAGCGGCTCCGCCGGGCGTCCTGGCAGCAGCACATGGATTAATTGATGTATGTTGAGTTTATGGAGCTGCC TTTTGGTGGCTTGCTTTATCTGCAGTTTTTAAGAAGAAAAAGAAGGCCCTGAGTCAAAGAAGATGCCTCGAACTAAACAAATTCATCCCA GAAATCTAAGAGACAAAATTGAAGAAGCACAAAAAGAACTTAATGGGGCAGAAGTTTCAAAAAAAGGCGACATGAATCCACTGGAAGGAA AGCAAGACTCTCACGTAGGAACGGTACACGCCCAGCTACAAAGGCAGCAGGCTACCGATTACTCCCAAGAGCAGCAAGGAAAGCTCCTGA GTCCTCGAAGTTTAGGAAGTACGGATTCTGGTTACTTTTCACGTTCTGAAAGTGCCGATCAAACAGTGAGTCCACCAACTCCCTTTGCCA GAAGGTTACCCAGCACAGAACAAGACTCTGGAAGGAGTAACGGACCCTCTGCAGCTCTTGTCACCACGTCAACACCCTCTGCTTTGCCCA CAGGGGAAAAGGCATTGCTTTTACCAGGTCAGATGCGCCCACCTTTGGCCACAAAAACACTTGAGGAGCGGATATCGAAGCTTATCTCAG ACAATGAAGCTTTGGTAGATGACAAGCAACTGGATAGTGTGAAGCCGCGGAGAACCTCACTGTCAAGACGAGGAAGCATTGATTCCCCCA AATCATACATATTTAAAGATTCTTTCCAGTTTGATTTAAAACCAGTGGGACGGAGAACAAGTTCAAGCTCTGATATACCGAAGTCACCTT TCACCCCTACTGAAAAATCAAAGCAAGTGTTTCTTCTGTCTGTACCTTCACTTGACTGTTTACCTATCACAAGAAGTAATTCCATGCCGA CCACAGGTTATTCAGCAGTACCTGCAAATATAATACCTCCTCCTCATCCACTAAGAGGAAGTCAGTCATTTGATGACAAAATTGGCACTT TCTATGATGATGTCTTTGTATCGGGACCTAACGCTCCTGTGCCCCAGAGTGGGCATCCCCGTACACTTGTGAGACAAGCAGCCATAGAAG ACTCTTCAGCAAATGAAAGTCATGTTCTTGGTACTGGACAGTCCCTGGATGAGAGCCACCAAGGATGCCATGCTGCTGGTGAAGCCATGT CAGTGAGGAGCAAGGCACTGGCACAAGGCCCACATATAGAAAAAAAGAAGTCTCATCAAGGGCGAGGGACAATGTTTGAGTGTGAAACTT GTAGAAACAGGTATAGGAAACTGGAAAATTTTGAAAATCATAAGAAATTTTACTGTTCTGAGTTACATGGACCAAAAACAAAGGTAGCCA TGAGAGAACCTGAGCACAGCCCTGTGCCCGGCGGTCTGCAGCCTCAGATTCTACACTACAGAGTCGCTGGGTCCTCCGGCATCTGGGAAC AGACGCCCCAGATAAGAAAAAGGAGGAAAATGAAAAGTGTTGGGGATGATGAAGAACTTCAGCAAAATGAAAGTGGAACATCTCCAAAAA GTTCTGAAGGCCTTCAGTTTCAGAATGCTCTGGGCTGTAATCCCAGTTTGCCTAAACATAATGTTACCATAAGAAGTGACCAGCAGCATA AAAATATACAGTTGCAAAACTCCCATATTCACCTTGTTGCCAGGGGCCCTGAGCAGACCATGGATCCCAAGCTGTCGACCATCATGGAAC AACAGATAAGTTCAGCAGCCCAGGACAAGATAGAACTGCAGAGACACGGAACTGGAATCTCTGTCATCCAGCACACCAACTCCCTGAGCA GGCCCAACTCATTTGACAAGCCTGAGCCTTTTGAAAGAGCCTCCCCAGTTTCTTTCCAGGAGCTGAATAGAACGGGGAAGTCCGGGTCTC TAAAAGTGATAGGAATCTCCCAAGAGGAAAGTCACCCTTCTCGGGACGGGTCTCATCCTCACCAGCTTGCACTATCAGACGCTCTCAGAG GAGAACTTCAGGAAAGCTCCAGAAAGAGTCCAAGTGAACGACATGTGTTAGGACAGCCCTCAAGACTTGTCCGGCAGCACAACATCCAAG TTCCAGAGATTTTGGTCACAGAAGAACCAGATCGAGACCTGGAAGCTCAATGCCATGATCAAGAAAAGTCAGAGAAGTTCAGTTGGCCCC AGCGTAGTGAAACCTTGTCAAAATTGCCAACAGAGAAACTGCCACCCAAAAAGAAAAGGCTCCGTCTGGCTGAGATAGAACATTCCTCAA CAGAATCGAGCTTTGATTCCACTCTCTCCAGGAGTCTAAGTAGGGAGAGCAGTTTATCTCACACTTCAAGTTTCTCAGCCTCTTTAGACA TAGAGGACGTTTCTAAAACGGAGGCTTCCCCCAAAATCGATTTTCTAAATAAAGCCGAGTTTCTTATGATTCCAGCTGGCTTGAATACTC TGAATGTTCCTGGATGTCACCGGGAAATGAGGCGTACTGCATCAGAACAGATTAATTGCACGCAAACGTCAATGGAGGTCTCTGATCTCA GAAGCAAATCATTCGATTGTGGAAGCATCACCCCACCCCAGACAACACCACTTACTGAATTGCAGCCTCCATCTTCACCTTCTCGAGTGG GAGTGACTGGGCATGTGCCTCTCTTAGAAAGAAGGAGAGGCCCACTGGTACGGCAAATATCTTTAAACATAGCCCCAGATAGTCATCTGT CTCCTGTACACCCAACATCTTTCCAAAATACTGCTCTTCCCAGTGTGAATGCAGTGCCATATCAGGGGCCTCAGCTCACTAGTACATCTT TAGCTGAGTTTTCTGCAAATACTTTGCACTCTCAGACTCAGGTTAAGGATCTGCAGGCAGAAACATCAAACTCCAGCTCTACCAACGTTT TTCCTGTTCAACAGCTCTGTGATATCAATTTGTTAAATCAAATCCATGCACCGCCTAGCCACCAGAGCACACAGCTATCTCTGCAAGTGT CTACGCAGGGTAGCAAGCCAGATAAAAATTCTGTTTTATCTGGGTCTTCTAAAAGTGAGGATTGCTTTGCTCCCAAATACCAATTGCATT GTCAGGTTTTCACTTCAGGCCCATCTTGCTCTTCTAATCCTGTGCATTCTTTGCCAAATCAAGTTATTTCAGATCCAGTTGGAACAGATC ATTGTGTGACATCAGCAACATTACCAACCAAATTAATTGACAGCATGTCTAATTCGCATCCTCTGCTACCACCAGAGCTCAGGCCCCTTG GAAGTCAGGTGCAGAAGGTGCCATCATCATTCATGCTGCCCATACGCCTGCAGAGTAGTGTTCCTGCTTACTGTTTTGCTACACTCACAT CCCTGCCACAAATACTAGTGACCCAAGATCTGCCCAATCAGCCAATTTGCCAGACTAATCATAGTGTAGTGCCAATCAGTGAAGAACAAA ATTCTGTGCCAACATTACAAAAAGGTCATCAGAATGCTTTGCCAAACCCAGAGAAGGAATTTCTATGTGAAAATGTTTTTTCAGAGATGA GCCAAAATTCTTCTCTATCAGAATCCTTGCCCATAACTCAGAAAATATCTGTTGGTCGACTTTCCCCTCAACAAGAATCTTCAGCTTCGA GTAAAAGGATGCTTTCCCCAGCAAATAGTTTAGACATTGCCATGGAAAAGCACCAGAAGCGGGCCAAAGATGAAAATGGAGCTGTTTGTG CAACAGACGTGAGACCTTTAGAGGCTTTGAGTTCGAGAGTTAATGAAGCTAGTAAACAGAAGAAGCCTATTTTAGTGAGACAGGTTTGTA CTACAGAGCCCCTGGACGGTGTGATGTTGGAAAAGGATGTTTTTTCTCAACCTGAAATTAGTAATGAGGCTGTTAATTTGACAAATGTTT TACCAGCTGATAATTCATCAACAGGATGCTCTAAATTTGTCGTTATAGAACCTATAAGTGAATTGCAGGAATTTGAAAACATCAAGTCAT CCACATCATTAACTCTTACAGTTCGAAGTTCACCTGCTCCTTCAGAAAATACTCATATTTCTCCTTTGAAATGTACAGACAATAACCAAG AAAGGAAGTCTCCAGGGGTTAAAAATCAAGGTGACAAAGTGAACATCCAAGAGCAAAGTCAACAGCCAGTCACTTCTCTTTCATTGTTTA ACATCAAGGACACCCAGCAGCTGGCTTTCCCTAGCCTGAAAACTACAACCAACTTTACATGGTGTTATCTCTTAAGGCAGAAGTCGTTGC ATTTGCCTCAGAAGGACCAGAAAACTTCAGCCTATACTGATTGGACAGTAAGCGCCAGTAATCCAAATCCACTCGGTTTGCCCACAAAAG TTGCACTTGCTCTCCTTAATTCAAAACAGAACACTGGAAAATCACTATACTGTCAAGCAATAACTACCCATTCCAAGTCAGACTTATTGG TCTATTCAAGCAAGTGGAAAAGCAGCTTAAGCAAGAAAAGGAAGAAAGCCCTTTACGAACCAGAGAGATTTTTCTAATATGGGAGAAGTT TATCACTCTTCTTATAAAGGTCCTCCATCTGAAGGAAGCTCAGAAACTTCATCACAGTCAGAAGAGTCCTATTTTTGTGGCATTTCAGCT TGCACAAGTCTGTGCAATGGACAGTCTCAAAAGACAAAAACTGAGAAGAGGGCTTTAAAACGAAGACGATCTAAAGTCCAAGACCAAGGA AAATTGATAAAAACTCTAATACAGACTAAGTCGGGATCATTGCCGAGCCTGCATGACATAATCAAAGGAAACAAAGAGATCACCGTGGGA ACATTTGGTGTTACAGCAGTCTCGGGACATATCTAAAATTAATTGAACTTTTCATACAGAAGACTTTTTTGTTGTTGTTCTTTGAAGAAC AGTCTGTAGTATTTGAAGGGTTTGGGGGAGGGAGAAAATATTAATGGGAAAGGCATTCAGAAATTATGGTTTCTACCTTTTTAAAAAGTA GATGGGATTGTGTCAATCTTGGTTAATGAGCTACAGTTTTACAAAGCTGATCACTTCCTATAAGGACAATGGTAGACATTTTATAAAGAT GTTTTTTCACAAGATTAATTACTGGGACAAAAGTAATTTGGAAGCCCAGTTCCTTAGGTGGGATAGGAATGAAAGCCTAAACCTCTTCCT TTAGCTTTGTTCCTATTTCTTGCACCTTCCCATATTTATGTGCCTTTTGTCTATTTATAATGCCACTGGAAGAGGAGGGATAACTTTTTC TGTTATTTGATTTCTTTTATAACTTTGTTAGGTTTTTGAAGCTGCAAACACTACAATGCTTTGAGGGGGTCTGTGCCTGAAGCTCAGGAG TGTGGATCAGACAGTCTAAAGATCCTAAAAACTTGCCAACTGGATCTTTGTTTAGCAAACTCACTGGAAATGAACACTTAATGGAATTTT TAAGTCTGTTCTGTTAGGTAGATGGTGATGCTCTTGTTATTTTCACTTATTCAGACTGGATTACTTCTTACTTAGTTACTAACTCAATGA GGAAAAATCCCTACAGGATCTTTTTTTGCAAACAACTGATATATGCAGACAAATTTTTGACAAATTCACCTTTTAAACACACTTAACCAT TTGTGAAGGTTTTCTTTAGCTTACATTTTAAACATACACAATAAACACTAATCCTCCAAACTTTCACTGTTTTTATTAGTATGAATATAA AATTTGAAGGTTTGGCCAATTAGTACAAGTCTCATGATATAATCACTGCCTGCATACATATGCACAGATCCAGTTAGTGAGTTTGTCAAG CTTAATCTAATTGGTTAAGTCTAAAGAGATTATTATTCCTTGATGTTTGCTTTGTATTGGCTACAAATGTGCAGAGGTAATACATATGTG ATGTCGATGTCTCTGTCTTTTTTTTTGTCTTTAAAAAATAATTGGCAGCAACTGTATTTGAATAAAATGATTTCTTAGTATGATTGTACA GTAATGAATGAAAGTGGAACATGTTTCTTTTTGAAAGGGAGAGAATTGACCATTTATTGTTGTGATGTTTAAGTTATAACTTATTGAGCA CTTTTAGTAGTGATAACTGTTTTTAAACTTGCCTAATACCTTTCTTGGGTATTGTTTGTAATGTGACTTATTTAACGCCTTTTTTGTTTG TTTAAGTTGCTGCTTTAGGTTAACAGCGTGTTTTAGAAGATTTAAATTTCTTTCCTGTCTGCACAATTAGCTATTCAGAGCAAGAGGGCC TGATTTTATAGAAGCCCCTTGAAAAGAGGTCCAGATGAGAGCAGAGATACAGTGAGAAATTATGTGATCTGTGTGTTGTGGGAAGAGAAT >In-frame_ENST00000379388_ENST00000367723_BE006447_HIVEP1_chr6_12121904_-_SUCO_chr1_172579038_length(amino acids)=1444AA_start in transcript=332_stop in transcript=4666 MPRTKQIHPRNLRDKIEEAQKELNGAEVSKKGDMNPLEGKQDSHVGTVHAQLQRQQATDYSQEQQGKLLSPRSLGSTDSGYFSRSESADQ TVSPPTPFARRLPSTEQDSGRSNGPSAALVTTSTPSALPTGEKALLLPGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSL SRRGSIDSPKSYIFKDSFQFDLKPVGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNSMPTTGYSAVPANIIPPPHPLRGS QSFDDKIGTFYDDVFVSGPNAPVPQSGHPRTLVRQAAIEDSSANESHVLGTGQSLDESHQGCHAAGEAMSVRSKALAQGPHIEKKKSHQG RGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTKVAMREPEHSPVPGGLQPQILHYRVAGSSGIWEQTPQIRKRRKMKSVGDDEELQ QNESGTSPKSSEGLQFQNALGCNPSLPKHNVTIRSDQQHKNIQLQNSHIHLVARGPEQTMDPKLSTIMEQQISSAAQDKIELQRHGTGIS VIQHTNSLSRPNSFDKPEPFERASPVSFQELNRTGKSGSLKVIGISQEESHPSRDGSHPHQLALSDALRGELQESSRKSPSERHVLGQPS RLVRQHNIQVPEILVTEEPDRDLEAQCHDQEKSEKFSWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFDSTLSRSLSRESSLSH TSSFSASLDIEDVSKTEASPKIDFLNKAEFLMIPAGLNTLNVPGCHREMRRTASEQINCTQTSMEVSDLRSKSFDCGSITPPQTTPLTEL QPPSSPSRVGVTGHVPLLERRRGPLVRQISLNIAPDSHLSPVHPTSFQNTALPSVNAVPYQGPQLTSTSLAEFSANTLHSQTQVKDLQAE TSNSSSTNVFPVQQLCDINLLNQIHAPPSHQSTQLSLQVSTQGSKPDKNSVLSGSSKSEDCFAPKYQLHCQVFTSGPSCSSNPVHSLPNQ VISDPVGTDHCVTSATLPTKLIDSMSNSHPLLPPELRPLGSQVQKVPSSFMLPIRLQSSVPAYCFATLTSLPQILVTQDLPNQPICQTNH SVVPISEEQNSVPTLQKGHQNALPNPEKEFLCENVFSEMSQNSSLSESLPITQKISVGRLSPQQESSASSKRMLSPANSLDIAMEKHQKR AKDENGAVCATDVRPLEALSSRVNEASKQKKPILVRQVCTTEPLDGVMLEKDVFSQPEISNEAVNLTNVLPADNSSTGCSKFVVIEPISE LQEFENIKSSTSLTLTVRSSPAPSENTHISPLKCTDNNQERKSPGVKNQGDKVNIQEQSQQPVTSLSLFNIKDTQQLAFPSLKTTTNFTW CYLLRQKSLHLPQKDQKTSAYTDWTVSASNPNPLGLPTKVALALLNSKQNTGKSLYCQAITTHSKSDLLVYSSKWKSSLSKKRKKALYEP -------------------------------------------------------------- >In-frame_ENST00000379388_ENST00000608151_BE006447_HIVEP1_chr6_12121904_-_SUCO_chr1_172579038_length(transcript)=6558nt_BP=4625nt GCTGCTGGGCGGCGGCAGGGTGGCGGACGGAGCGGGGGACCGGGGAGCGGCGGCCGCCGGAGGAGGTTATGTTTGTGTTTGGGGTTGTCA AGTGAAGGAGGGATCCCAGGCGCCGCCGCCGCCGCCGCGCGGGGGTCGCGGAGATCCCGAGCCGCGGCCGCCGCCATCAGCAGCGCAGCT CCAGGGCCGGCTGCAGCGGCAGCGGCTCCGCCGGGCGTCCTGGCAGCAGCACATGGATTAATTGATGTATGTTGAGTTTATGGAGCTGCC TTTTGGTGGCTTGCTTTATCTGCAGTTTTTAAGAAGAAAAAGAAGGCCCTGAGTCAAAGAAGATGCCTCGAACTAAACAAATTCATCCCA GAAATCTAAGAGACAAAATTGAAGAAGCACAAAAAGAACTTAATGGGGCAGAAGTTTCAAAAAAAGGCGACATGAATCCACTGGAAGGAA AGCAAGACTCTCACGTAGGAACGGTACACGCCCAGCTACAAAGGCAGCAGGCTACCGATTACTCCCAAGAGCAGCAAGGAAAGCTCCTGA GTCCTCGAAGTTTAGGAAGTACGGATTCTGGTTACTTTTCACGTTCTGAAAGTGCCGATCAAACAGTGAGTCCACCAACTCCCTTTGCCA GAAGGTTACCCAGCACAGAACAAGACTCTGGAAGGAGTAACGGACCCTCTGCAGCTCTTGTCACCACGTCAACACCCTCTGCTTTGCCCA CAGGGGAAAAGGCATTGCTTTTACCAGGTCAGATGCGCCCACCTTTGGCCACAAAAACACTTGAGGAGCGGATATCGAAGCTTATCTCAG ACAATGAAGCTTTGGTAGATGACAAGCAACTGGATAGTGTGAAGCCGCGGAGAACCTCACTGTCAAGACGAGGAAGCATTGATTCCCCCA AATCATACATATTTAAAGATTCTTTCCAGTTTGATTTAAAACCAGTGGGACGGAGAACAAGTTCAAGCTCTGATATACCGAAGTCACCTT TCACCCCTACTGAAAAATCAAAGCAAGTGTTTCTTCTGTCTGTACCTTCACTTGACTGTTTACCTATCACAAGAAGTAATTCCATGCCGA CCACAGGTTATTCAGCAGTACCTGCAAATATAATACCTCCTCCTCATCCACTAAGAGGAAGTCAGTCATTTGATGACAAAATTGGCACTT TCTATGATGATGTCTTTGTATCGGGACCTAACGCTCCTGTGCCCCAGAGTGGGCATCCCCGTACACTTGTGAGACAAGCAGCCATAGAAG ACTCTTCAGCAAATGAAAGTCATGTTCTTGGTACTGGACAGTCCCTGGATGAGAGCCACCAAGGATGCCATGCTGCTGGTGAAGCCATGT CAGTGAGGAGCAAGGCACTGGCACAAGGCCCACATATAGAAAAAAAGAAGTCTCATCAAGGGCGAGGGACAATGTTTGAGTGTGAAACTT GTAGAAACAGGTATAGGAAACTGGAAAATTTTGAAAATCATAAGAAATTTTACTGTTCTGAGTTACATGGACCAAAAACAAAGGTAGCCA TGAGAGAACCTGAGCACAGCCCTGTGCCCGGCGGTCTGCAGCCTCAGATTCTACACTACAGAGTCGCTGGGTCCTCCGGCATCTGGGAAC AGACGCCCCAGATAAGAAAAAGGAGGAAAATGAAAAGTGTTGGGGATGATGAAGAACTTCAGCAAAATGAAAGTGGAACATCTCCAAAAA GTTCTGAAGGCCTTCAGTTTCAGAATGCTCTGGGCTGTAATCCCAGTTTGCCTAAACATAATGTTACCATAAGAAGTGACCAGCAGCATA AAAATATACAGTTGCAAAACTCCCATATTCACCTTGTTGCCAGGGGCCCTGAGCAGACCATGGATCCCAAGCTGTCGACCATCATGGAAC AACAGATAAGTTCAGCAGCCCAGGACAAGATAGAACTGCAGAGACACGGAACTGGAATCTCTGTCATCCAGCACACCAACTCCCTGAGCA GGCCCAACTCATTTGACAAGCCTGAGCCTTTTGAAAGAGCCTCCCCAGTTTCTTTCCAGGAGCTGAATAGAACGGGGAAGTCCGGGTCTC TAAAAGTGATAGGAATCTCCCAAGAGGAAAGTCACCCTTCTCGGGACGGGTCTCATCCTCACCAGCTTGCACTATCAGACGCTCTCAGAG GAGAACTTCAGGAAAGCTCCAGAAAGAGTCCAAGTGAACGACATGTGTTAGGACAGCCCTCAAGACTTGTCCGGCAGCACAACATCCAAG TTCCAGAGATTTTGGTCACAGAAGAACCAGATCGAGACCTGGAAGCTCAATGCCATGATCAAGAAAAGTCAGAGAAGTTCAGTTGGCCCC AGCGTAGTGAAACCTTGTCAAAATTGCCAACAGAGAAACTGCCACCCAAAAAGAAAAGGCTCCGTCTGGCTGAGATAGAACATTCCTCAA CAGAATCGAGCTTTGATTCCACTCTCTCCAGGAGTCTAAGTAGGGAGAGCAGTTTATCTCACACTTCAAGTTTCTCAGCCTCTTTAGACA TAGAGGACGTTTCTAAAACGGAGGCTTCCCCCAAAATCGATTTTCTAAATAAAGCCGAGTTTCTTATGATTCCAGCTGGCTTGAATACTC TGAATGTTCCTGGATGTCACCGGGAAATGAGGCGTACTGCATCAGAACAGATTAATTGCACGCAAACGTCAATGGAGGTCTCTGATCTCA GAAGCAAATCATTCGATTGTGGAAGCATCACCCCACCCCAGACAACACCACTTACTGAATTGCAGCCTCCATCTTCACCTTCTCGAGTGG GAGTGACTGGGCATGTGCCTCTCTTAGAAAGAAGGAGAGGCCCACTGGTACGGCAAATATCTTTAAACATAGCCCCAGATAGTCATCTGT CTCCTGTACACCCAACATCTTTCCAAAATACTGCTCTTCCCAGTGTGAATGCAGTGCCATATCAGGGGCCTCAGCTCACTAGTACATCTT TAGCTGAGTTTTCTGCAAATACTTTGCACTCTCAGACTCAGGTTAAGGATCTGCAGGCAGAAACATCAAACTCCAGCTCTACCAACGTTT TTCCTGTTCAACAGCTCTGTGATATCAATTTGTTAAATCAAATCCATGCACCGCCTAGCCACCAGAGCACACAGCTATCTCTGCAAGTGT CTACGCAGGGTAGCAAGCCAGATAAAAATTCTGTTTTATCTGGGTCTTCTAAAAGTGAGGATTGCTTTGCTCCCAAATACCAATTGCATT GTCAGGTTTTCACTTCAGGCCCATCTTGCTCTTCTAATCCTGTGCATTCTTTGCCAAATCAAGTTATTTCAGATCCAGTTGGAACAGATC ATTGTGTGACATCAGCAACATTACCAACCAAATTAATTGACAGCATGTCTAATTCGCATCCTCTGCTACCACCAGAGCTCAGGCCCCTTG GAAGTCAGGTGCAGAAGGTGCCATCATCATTCATGCTGCCCATACGCCTGCAGAGTAGTGTTCCTGCTTACTGTTTTGCTACACTCACAT CCCTGCCACAAATACTAGTGACCCAAGATCTGCCCAATCAGCCAATTTGCCAGACTAATCATAGTGTAGTGCCAATCAGTGAAGAACAAA ATTCTGTGCCAACATTACAAAAAGGTCATCAGAATGCTTTGCCAAACCCAGAGAAGGAATTTCTATGTGAAAATGTTTTTTCAGAGATGA GCCAAAATTCTTCTCTATCAGAATCCTTGCCCATAACTCAGAAAATATCTGTTGGTCGACTTTCCCCTCAACAAGAATCTTCAGCTTCGA GTAAAAGGATGCTTTCCCCAGCAAATAGTTTAGACATTGCCATGGAAAAGCACCAGAAGCGGGCCAAAGATGAAAATGGAGCTGTTTGTG CAACAGACGTGAGACCTTTAGAGGCTTTGAGTTCGAGAGTTAATGAAGCTAGTAAACAGAAGAAGCCTATTTTAGTGAGACAGGTTTGTA CTACAGAGCCCCTGGACGGTGTGATGTTGGAAAAGGATGTTTTTTCTCAACCTGAAATTAGTAATGAGGCTGTTAATTTGACAAATGTTT TACCAGCTGATAATTCATCAACAGGATGCTCTAAATTTGTCGTTATAGAACCTATAAGTGAATTGCAGGAATTTGAAAACATCAAGTCAT CCACATCATTAACTCTTACAGTTCGAAGTTCACCTGCTCCTTCAGAAAATACTCATATTTCTCCTTTGAAATGTACAGACAATAACCAAG AAAGGAAGTCTCCAGGGGTTAAAAATCAAGGTGACAAAGTGAACATCCAAGAGCAAAGTCAACAGCCAGTCACTTCTCTTTCATTGTTTA ACATCAAGGACACCCAGCAGCTGGCTTTCCCTAGCCTGAAAACTACAACCAACTTTACATGGTGTTATCTCTTAAGGCAGAAGTCGTTGC ATTTGCCTCAGAAGGACCAGAAAACTTCAGCCTATACTGATTGGACAGTAAGCGCCAGTAATCCAAATCCACTCGGTTTGCCCACAAAAG TTGCACTTGCTCTCCTTAATTCAAAACAGAACACTGGAAAATCACTATACTGTCAAGCAATAACTACCCATTCCAAGTCAGACTTATTGG TCTATTCAAGCAAGTGGAAAAGCAGCTTAAGCAAGAAAAGGAAGAAAGCCCTTTACGAACCAGAGAGATTTTTCTAATATGGGAGAAGTT TATCACTCTTCTTATAAAGGTCCTCCATCTGAAGGAAGCTCAGAAACTTCATCACAGTCAGAAGAGTCCTATTTTTGTGGCATTTCAGCT TGCACAAGTCTGTGCAATGGACAGTCTCAAAAGACAAAAACTGAGAAGAGGGCTTTAAAACGAAGACGATCTAAAGTCCAAGACCAAGGA AAATTGATAAAAACTCTAATACAGACTAAGTCGGGATCATTGCCGAGCCTGCATGACATAATCAAAGGAAACAAAGAGATCACCGTGGGA ACATTTGGTGTTACAGCAGTCTCGGGACATATCTAAAATTAATTGAACTTTTCATACAGAAGACTTTTTTGTTGTTGTTCTTTGAAGAAC AGTCTGTAGTATTTGAAGGGTTTGGGGGAGGGAGAAAATATTAATGGGAAAGGCATTCAGAAATTATGGTTTCTACCTTTTTAAAAAGTA GATGGGATTGTGTCAATCTTGGTTAATGAGCTACAGTTTTACAAAGCTGATCACTTCCTATAAGGACAATGGTAGACATTTTATAAAGAT GTTTTTTCACAAGATTAATTACTGGGACAAAAGTAATTTGGAAGCCCAGTTCCTTAGGTGGGATAGGAATGAAAGCCTAAACCTCTTCCT TTAGCTTTGTTCCTATTTCTTGCACCTTCCCATATTTATGTGCCTTTTGTCTATTTATAATGCCACTGGAAGAGGAGGGATAACTTTTTC TGTTATTTGATTTCTTTTATAACTTTGTTAGGTTTTTGAAGCTGCAAACACTACAATGCTTTGAGGGGGTCTGTGCCTGAAGCTCAGGAG TGTGGATCAGACAGTCTAAAGATCCTAAAAACTTGCCAACTGGATCTTTGTTTAGCAAACTCACTGGAAATGAACACTTAATGGAATTTT TAAGTCTGTTCTGTTAGGTAGATGGTGATGCTCTTGTTATTTTCACTTATTCAGACTGGATTACTTCTTACTTAGTTACTAACTCAATGA GGAAAAATCCCTACAGGATCTTTTTTTGCAAACAACTGATATATGCAGACAAATTTTTGACAAATTCACCTTTTAAACACACTTAACCAT TTGTGAAGGTTTTCTTTAGCTTACATTTTAAACATACACAATAAACACTAATCCTCCAAACTTTCACTGTTTTTATTAGTATGAATATAA AATTTGAAGGTTTGGCCAATTAGTACAAGTCTCATGATATAATCACTGCCTGCATACATATGCACAGATCCAGTTAGTGAGTTTGTCAAG CTTAATCTAATTGGTTAAGTCTAAAGAGATTATTATTCCTTGATGTTTGCTTTGTATTGGCTACAAATGTGCAGAGGTAATACATATGTG ATGTCGATGTCTCTGTCTTTTTTTTTGTCTTTAAAAAATAATTGGCAGCAACTGTATTTGAATAAAATGATTTCTTAGTATGATTGTACA GTAATGAATGAAAGTGGAACATGTTTCTTTTTGAAAGGGAGAGAATTGACCATTTATTGTTGTGATGTTTAAGTTATAACTTATTGAGCA CTTTTAGTAGTGATAACTGTTTTTAAACTTGCCTAATACCTTTCTTGGGTATTGTTTGTAATGTGACTTATTTAACGCCTTTTTTGTTTG TTTAAGTTGCTGCTTTAGGTTAACAGCGTGTTTTAGAAGATTTAAATTTCTTTCCTGTCTGCACAATTAGCTATTCAGAGCAAGAGGGCC TGATTTTATAGAAGCCCCTTGAAAAGAGGTCCAGATGAGAGCAGAGATACAGTGAGAAATTATGTGATCTGTGTGTTGTGGGAAGAGAAT >In-frame_ENST00000379388_ENST00000608151_BE006447_HIVEP1_chr6_12121904_-_SUCO_chr1_172579038_length(amino acids)=1444AA_start in transcript=332_stop in transcript=4666 MPRTKQIHPRNLRDKIEEAQKELNGAEVSKKGDMNPLEGKQDSHVGTVHAQLQRQQATDYSQEQQGKLLSPRSLGSTDSGYFSRSESADQ TVSPPTPFARRLPSTEQDSGRSNGPSAALVTTSTPSALPTGEKALLLPGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSL SRRGSIDSPKSYIFKDSFQFDLKPVGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNSMPTTGYSAVPANIIPPPHPLRGS QSFDDKIGTFYDDVFVSGPNAPVPQSGHPRTLVRQAAIEDSSANESHVLGTGQSLDESHQGCHAAGEAMSVRSKALAQGPHIEKKKSHQG RGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTKVAMREPEHSPVPGGLQPQILHYRVAGSSGIWEQTPQIRKRRKMKSVGDDEELQ QNESGTSPKSSEGLQFQNALGCNPSLPKHNVTIRSDQQHKNIQLQNSHIHLVARGPEQTMDPKLSTIMEQQISSAAQDKIELQRHGTGIS VIQHTNSLSRPNSFDKPEPFERASPVSFQELNRTGKSGSLKVIGISQEESHPSRDGSHPHQLALSDALRGELQESSRKSPSERHVLGQPS RLVRQHNIQVPEILVTEEPDRDLEAQCHDQEKSEKFSWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFDSTLSRSLSRESSLSH TSSFSASLDIEDVSKTEASPKIDFLNKAEFLMIPAGLNTLNVPGCHREMRRTASEQINCTQTSMEVSDLRSKSFDCGSITPPQTTPLTEL QPPSSPSRVGVTGHVPLLERRRGPLVRQISLNIAPDSHLSPVHPTSFQNTALPSVNAVPYQGPQLTSTSLAEFSANTLHSQTQVKDLQAE TSNSSSTNVFPVQQLCDINLLNQIHAPPSHQSTQLSLQVSTQGSKPDKNSVLSGSSKSEDCFAPKYQLHCQVFTSGPSCSSNPVHSLPNQ VISDPVGTDHCVTSATLPTKLIDSMSNSHPLLPPELRPLGSQVQKVPSSFMLPIRLQSSVPAYCFATLTSLPQILVTQDLPNQPICQTNH SVVPISEEQNSVPTLQKGHQNALPNPEKEFLCENVFSEMSQNSSLSESLPITQKISVGRLSPQQESSASSKRMLSPANSLDIAMEKHQKR AKDENGAVCATDVRPLEALSSRVNEASKQKKPILVRQVCTTEPLDGVMLEKDVFSQPEISNEAVNLTNVLPADNSSTGCSKFVVIEPISE LQEFENIKSSTSLTLTVRSSPAPSENTHISPLKCTDNNQERKSPGVKNQGDKVNIQEQSQQPVTSLSLFNIKDTQQLAFPSLKTTTNFTW CYLLRQKSLHLPQKDQKTSAYTDWTVSASNPNPLGLPTKVALALLNSKQNTGKSLYCQAITTHSKSDLLVYSSKWKSSLSKKRKKALYEP -------------------------------------------------------------- >In-frame_ENST00000379388_ENST00000263688_BE006447_HIVEP1_chr6_12121904_-_SUCO_chr1_172579038_length(transcript)=6558nt_BP=4625nt GCTGCTGGGCGGCGGCAGGGTGGCGGACGGAGCGGGGGACCGGGGAGCGGCGGCCGCCGGAGGAGGTTATGTTTGTGTTTGGGGTTGTCA AGTGAAGGAGGGATCCCAGGCGCCGCCGCCGCCGCCGCGCGGGGGTCGCGGAGATCCCGAGCCGCGGCCGCCGCCATCAGCAGCGCAGCT CCAGGGCCGGCTGCAGCGGCAGCGGCTCCGCCGGGCGTCCTGGCAGCAGCACATGGATTAATTGATGTATGTTGAGTTTATGGAGCTGCC TTTTGGTGGCTTGCTTTATCTGCAGTTTTTAAGAAGAAAAAGAAGGCCCTGAGTCAAAGAAGATGCCTCGAACTAAACAAATTCATCCCA GAAATCTAAGAGACAAAATTGAAGAAGCACAAAAAGAACTTAATGGGGCAGAAGTTTCAAAAAAAGGCGACATGAATCCACTGGAAGGAA AGCAAGACTCTCACGTAGGAACGGTACACGCCCAGCTACAAAGGCAGCAGGCTACCGATTACTCCCAAGAGCAGCAAGGAAAGCTCCTGA GTCCTCGAAGTTTAGGAAGTACGGATTCTGGTTACTTTTCACGTTCTGAAAGTGCCGATCAAACAGTGAGTCCACCAACTCCCTTTGCCA GAAGGTTACCCAGCACAGAACAAGACTCTGGAAGGAGTAACGGACCCTCTGCAGCTCTTGTCACCACGTCAACACCCTCTGCTTTGCCCA CAGGGGAAAAGGCATTGCTTTTACCAGGTCAGATGCGCCCACCTTTGGCCACAAAAACACTTGAGGAGCGGATATCGAAGCTTATCTCAG ACAATGAAGCTTTGGTAGATGACAAGCAACTGGATAGTGTGAAGCCGCGGAGAACCTCACTGTCAAGACGAGGAAGCATTGATTCCCCCA AATCATACATATTTAAAGATTCTTTCCAGTTTGATTTAAAACCAGTGGGACGGAGAACAAGTTCAAGCTCTGATATACCGAAGTCACCTT TCACCCCTACTGAAAAATCAAAGCAAGTGTTTCTTCTGTCTGTACCTTCACTTGACTGTTTACCTATCACAAGAAGTAATTCCATGCCGA CCACAGGTTATTCAGCAGTACCTGCAAATATAATACCTCCTCCTCATCCACTAAGAGGAAGTCAGTCATTTGATGACAAAATTGGCACTT TCTATGATGATGTCTTTGTATCGGGACCTAACGCTCCTGTGCCCCAGAGTGGGCATCCCCGTACACTTGTGAGACAAGCAGCCATAGAAG ACTCTTCAGCAAATGAAAGTCATGTTCTTGGTACTGGACAGTCCCTGGATGAGAGCCACCAAGGATGCCATGCTGCTGGTGAAGCCATGT CAGTGAGGAGCAAGGCACTGGCACAAGGCCCACATATAGAAAAAAAGAAGTCTCATCAAGGGCGAGGGACAATGTTTGAGTGTGAAACTT GTAGAAACAGGTATAGGAAACTGGAAAATTTTGAAAATCATAAGAAATTTTACTGTTCTGAGTTACATGGACCAAAAACAAAGGTAGCCA TGAGAGAACCTGAGCACAGCCCTGTGCCCGGCGGTCTGCAGCCTCAGATTCTACACTACAGAGTCGCTGGGTCCTCCGGCATCTGGGAAC AGACGCCCCAGATAAGAAAAAGGAGGAAAATGAAAAGTGTTGGGGATGATGAAGAACTTCAGCAAAATGAAAGTGGAACATCTCCAAAAA GTTCTGAAGGCCTTCAGTTTCAGAATGCTCTGGGCTGTAATCCCAGTTTGCCTAAACATAATGTTACCATAAGAAGTGACCAGCAGCATA AAAATATACAGTTGCAAAACTCCCATATTCACCTTGTTGCCAGGGGCCCTGAGCAGACCATGGATCCCAAGCTGTCGACCATCATGGAAC AACAGATAAGTTCAGCAGCCCAGGACAAGATAGAACTGCAGAGACACGGAACTGGAATCTCTGTCATCCAGCACACCAACTCCCTGAGCA GGCCCAACTCATTTGACAAGCCTGAGCCTTTTGAAAGAGCCTCCCCAGTTTCTTTCCAGGAGCTGAATAGAACGGGGAAGTCCGGGTCTC TAAAAGTGATAGGAATCTCCCAAGAGGAAAGTCACCCTTCTCGGGACGGGTCTCATCCTCACCAGCTTGCACTATCAGACGCTCTCAGAG GAGAACTTCAGGAAAGCTCCAGAAAGAGTCCAAGTGAACGACATGTGTTAGGACAGCCCTCAAGACTTGTCCGGCAGCACAACATCCAAG TTCCAGAGATTTTGGTCACAGAAGAACCAGATCGAGACCTGGAAGCTCAATGCCATGATCAAGAAAAGTCAGAGAAGTTCAGTTGGCCCC AGCGTAGTGAAACCTTGTCAAAATTGCCAACAGAGAAACTGCCACCCAAAAAGAAAAGGCTCCGTCTGGCTGAGATAGAACATTCCTCAA CAGAATCGAGCTTTGATTCCACTCTCTCCAGGAGTCTAAGTAGGGAGAGCAGTTTATCTCACACTTCAAGTTTCTCAGCCTCTTTAGACA TAGAGGACGTTTCTAAAACGGAGGCTTCCCCCAAAATCGATTTTCTAAATAAAGCCGAGTTTCTTATGATTCCAGCTGGCTTGAATACTC TGAATGTTCCTGGATGTCACCGGGAAATGAGGCGTACTGCATCAGAACAGATTAATTGCACGCAAACGTCAATGGAGGTCTCTGATCTCA GAAGCAAATCATTCGATTGTGGAAGCATCACCCCACCCCAGACAACACCACTTACTGAATTGCAGCCTCCATCTTCACCTTCTCGAGTGG GAGTGACTGGGCATGTGCCTCTCTTAGAAAGAAGGAGAGGCCCACTGGTACGGCAAATATCTTTAAACATAGCCCCAGATAGTCATCTGT CTCCTGTACACCCAACATCTTTCCAAAATACTGCTCTTCCCAGTGTGAATGCAGTGCCATATCAGGGGCCTCAGCTCACTAGTACATCTT TAGCTGAGTTTTCTGCAAATACTTTGCACTCTCAGACTCAGGTTAAGGATCTGCAGGCAGAAACATCAAACTCCAGCTCTACCAACGTTT TTCCTGTTCAACAGCTCTGTGATATCAATTTGTTAAATCAAATCCATGCACCGCCTAGCCACCAGAGCACACAGCTATCTCTGCAAGTGT CTACGCAGGGTAGCAAGCCAGATAAAAATTCTGTTTTATCTGGGTCTTCTAAAAGTGAGGATTGCTTTGCTCCCAAATACCAATTGCATT GTCAGGTTTTCACTTCAGGCCCATCTTGCTCTTCTAATCCTGTGCATTCTTTGCCAAATCAAGTTATTTCAGATCCAGTTGGAACAGATC ATTGTGTGACATCAGCAACATTACCAACCAAATTAATTGACAGCATGTCTAATTCGCATCCTCTGCTACCACCAGAGCTCAGGCCCCTTG GAAGTCAGGTGCAGAAGGTGCCATCATCATTCATGCTGCCCATACGCCTGCAGAGTAGTGTTCCTGCTTACTGTTTTGCTACACTCACAT CCCTGCCACAAATACTAGTGACCCAAGATCTGCCCAATCAGCCAATTTGCCAGACTAATCATAGTGTAGTGCCAATCAGTGAAGAACAAA ATTCTGTGCCAACATTACAAAAAGGTCATCAGAATGCTTTGCCAAACCCAGAGAAGGAATTTCTATGTGAAAATGTTTTTTCAGAGATGA GCCAAAATTCTTCTCTATCAGAATCCTTGCCCATAACTCAGAAAATATCTGTTGGTCGACTTTCCCCTCAACAAGAATCTTCAGCTTCGA GTAAAAGGATGCTTTCCCCAGCAAATAGTTTAGACATTGCCATGGAAAAGCACCAGAAGCGGGCCAAAGATGAAAATGGAGCTGTTTGTG CAACAGACGTGAGACCTTTAGAGGCTTTGAGTTCGAGAGTTAATGAAGCTAGTAAACAGAAGAAGCCTATTTTAGTGAGACAGGTTTGTA CTACAGAGCCCCTGGACGGTGTGATGTTGGAAAAGGATGTTTTTTCTCAACCTGAAATTAGTAATGAGGCTGTTAATTTGACAAATGTTT TACCAGCTGATAATTCATCAACAGGATGCTCTAAATTTGTCGTTATAGAACCTATAAGTGAATTGCAGGAATTTGAAAACATCAAGTCAT CCACATCATTAACTCTTACAGTTCGAAGTTCACCTGCTCCTTCAGAAAATACTCATATTTCTCCTTTGAAATGTACAGACAATAACCAAG AAAGGAAGTCTCCAGGGGTTAAAAATCAAGGTGACAAAGTGAACATCCAAGAGCAAAGTCAACAGCCAGTCACTTCTCTTTCATTGTTTA ACATCAAGGACACCCAGCAGCTGGCTTTCCCTAGCCTGAAAACTACAACCAACTTTACATGGTGTTATCTCTTAAGGCAGAAGTCGTTGC ATTTGCCTCAGAAGGACCAGAAAACTTCAGCCTATACTGATTGGACAGTAAGCGCCAGTAATCCAAATCCACTCGGTTTGCCCACAAAAG TTGCACTTGCTCTCCTTAATTCAAAACAGAACACTGGAAAATCACTATACTGTCAAGCAATAACTACCCATTCCAAGTCAGACTTATTGG TCTATTCAAGCAAGTGGAAAAGCAGCTTAAGCAAGAAAAGGAAGAAAGCCCTTTACGAACCAGAGAGATTTTTCTAATATGGGAGAAGTT TATCACTCTTCTTATAAAGGTCCTCCATCTGAAGGAAGCTCAGAAACTTCATCACAGTCAGAAGAGTCCTATTTTTGTGGCATTTCAGCT TGCACAAGTCTGTGCAATGGACAGTCTCAAAAGACAAAAACTGAGAAGAGGGCTTTAAAACGAAGACGATCTAAAGTCCAAGACCAAGGA AAATTGATAAAAACTCTAATACAGACTAAGTCGGGATCATTGCCGAGCCTGCATGACATAATCAAAGGAAACAAAGAGATCACCGTGGGA ACATTTGGTGTTACAGCAGTCTCGGGACATATCTAAAATTAATTGAACTTTTCATACAGAAGACTTTTTTGTTGTTGTTCTTTGAAGAAC AGTCTGTAGTATTTGAAGGGTTTGGGGGAGGGAGAAAATATTAATGGGAAAGGCATTCAGAAATTATGGTTTCTACCTTTTTAAAAAGTA GATGGGATTGTGTCAATCTTGGTTAATGAGCTACAGTTTTACAAAGCTGATCACTTCCTATAAGGACAATGGTAGACATTTTATAAAGAT GTTTTTTCACAAGATTAATTACTGGGACAAAAGTAATTTGGAAGCCCAGTTCCTTAGGTGGGATAGGAATGAAAGCCTAAACCTCTTCCT TTAGCTTTGTTCCTATTTCTTGCACCTTCCCATATTTATGTGCCTTTTGTCTATTTATAATGCCACTGGAAGAGGAGGGATAACTTTTTC TGTTATTTGATTTCTTTTATAACTTTGTTAGGTTTTTGAAGCTGCAAACACTACAATGCTTTGAGGGGGTCTGTGCCTGAAGCTCAGGAG TGTGGATCAGACAGTCTAAAGATCCTAAAAACTTGCCAACTGGATCTTTGTTTAGCAAACTCACTGGAAATGAACACTTAATGGAATTTT TAAGTCTGTTCTGTTAGGTAGATGGTGATGCTCTTGTTATTTTCACTTATTCAGACTGGATTACTTCTTACTTAGTTACTAACTCAATGA GGAAAAATCCCTACAGGATCTTTTTTTGCAAACAACTGATATATGCAGACAAATTTTTGACAAATTCACCTTTTAAACACACTTAACCAT TTGTGAAGGTTTTCTTTAGCTTACATTTTAAACATACACAATAAACACTAATCCTCCAAACTTTCACTGTTTTTATTAGTATGAATATAA AATTTGAAGGTTTGGCCAATTAGTACAAGTCTCATGATATAATCACTGCCTGCATACATATGCACAGATCCAGTTAGTGAGTTTGTCAAG CTTAATCTAATTGGTTAAGTCTAAAGAGATTATTATTCCTTGATGTTTGCTTTGTATTGGCTACAAATGTGCAGAGGTAATACATATGTG ATGTCGATGTCTCTGTCTTTTTTTTTGTCTTTAAAAAATAATTGGCAGCAACTGTATTTGAATAAAATGATTTCTTAGTATGATTGTACA GTAATGAATGAAAGTGGAACATGTTTCTTTTTGAAAGGGAGAGAATTGACCATTTATTGTTGTGATGTTTAAGTTATAACTTATTGAGCA CTTTTAGTAGTGATAACTGTTTTTAAACTTGCCTAATACCTTTCTTGGGTATTGTTTGTAATGTGACTTATTTAACGCCTTTTTTGTTTG TTTAAGTTGCTGCTTTAGGTTAACAGCGTGTTTTAGAAGATTTAAATTTCTTTCCTGTCTGCACAATTAGCTATTCAGAGCAAGAGGGCC TGATTTTATAGAAGCCCCTTGAAAAGAGGTCCAGATGAGAGCAGAGATACAGTGAGAAATTATGTGATCTGTGTGTTGTGGGAAGAGAAT >In-frame_ENST00000379388_ENST00000263688_BE006447_HIVEP1_chr6_12121904_-_SUCO_chr1_172579038_length(amino acids)=1444AA_start in transcript=332_stop in transcript=4666 MPRTKQIHPRNLRDKIEEAQKELNGAEVSKKGDMNPLEGKQDSHVGTVHAQLQRQQATDYSQEQQGKLLSPRSLGSTDSGYFSRSESADQ TVSPPTPFARRLPSTEQDSGRSNGPSAALVTTSTPSALPTGEKALLLPGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSL SRRGSIDSPKSYIFKDSFQFDLKPVGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNSMPTTGYSAVPANIIPPPHPLRGS QSFDDKIGTFYDDVFVSGPNAPVPQSGHPRTLVRQAAIEDSSANESHVLGTGQSLDESHQGCHAAGEAMSVRSKALAQGPHIEKKKSHQG RGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTKVAMREPEHSPVPGGLQPQILHYRVAGSSGIWEQTPQIRKRRKMKSVGDDEELQ QNESGTSPKSSEGLQFQNALGCNPSLPKHNVTIRSDQQHKNIQLQNSHIHLVARGPEQTMDPKLSTIMEQQISSAAQDKIELQRHGTGIS VIQHTNSLSRPNSFDKPEPFERASPVSFQELNRTGKSGSLKVIGISQEESHPSRDGSHPHQLALSDALRGELQESSRKSPSERHVLGQPS RLVRQHNIQVPEILVTEEPDRDLEAQCHDQEKSEKFSWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFDSTLSRSLSRESSLSH TSSFSASLDIEDVSKTEASPKIDFLNKAEFLMIPAGLNTLNVPGCHREMRRTASEQINCTQTSMEVSDLRSKSFDCGSITPPQTTPLTEL QPPSSPSRVGVTGHVPLLERRRGPLVRQISLNIAPDSHLSPVHPTSFQNTALPSVNAVPYQGPQLTSTSLAEFSANTLHSQTQVKDLQAE TSNSSSTNVFPVQQLCDINLLNQIHAPPSHQSTQLSLQVSTQGSKPDKNSVLSGSSKSEDCFAPKYQLHCQVFTSGPSCSSNPVHSLPNQ VISDPVGTDHCVTSATLPTKLIDSMSNSHPLLPPELRPLGSQVQKVPSSFMLPIRLQSSVPAYCFATLTSLPQILVTQDLPNQPICQTNH SVVPISEEQNSVPTLQKGHQNALPNPEKEFLCENVFSEMSQNSSLSESLPITQKISVGRLSPQQESSASSKRMLSPANSLDIAMEKHQKR AKDENGAVCATDVRPLEALSSRVNEASKQKKPILVRQVCTTEPLDGVMLEKDVFSQPEISNEAVNLTNVLPADNSSTGCSKFVVIEPISE LQEFENIKSSTSLTLTVRSSPAPSENTHISPLKCTDNNQERKSPGVKNQGDKVNIQEQSQQPVTSLSLFNIKDTQQLAFPSLKTTTNFTW CYLLRQKSLHLPQKDQKTSAYTDWTVSASNPNPLGLPTKVALALLNSKQNTGKSLYCQAITTHSKSDLLVYSSKWKSSLSKKRKKALYEP -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for HIVEP1-SUCO |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for HIVEP1-SUCO |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for HIVEP1-SUCO |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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