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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ALB-ADH1C (FusionGDB2 ID:3842)

Fusion Gene Summary for ALB-ADH1C

check button Fusion gene summary
Fusion gene informationFusion gene name: ALB-ADH1C
Fusion gene ID: 3842
HgeneTgene
Gene symbol

ALB

ADH1C

Gene ID

213

126

Gene namealbuminalcohol dehydrogenase 1C (class I), gamma polypeptide
SynonymsHSA|PRO0883|PRO0903|PRO1341ADH3
Cytomap

4q13.3

4q23

Type of geneprotein-codingprotein-coding
Descriptionserum albuminalcohol dehydrogenase 1CADH, gamma subunitalcohol dehydrogenase 3 (class I), gamma polypeptidealdehyde reductase
Modification date2020032920200313
UniProtAcc

P02768

P00326

Ensembl transtripts involved in fusion geneENST00000295897, ENST00000415165, 
ENST00000503124, ENST00000509063, 
ENST00000401494, ENST00000505649, 
ENST00000515683, ENST00000510055, 
Fusion gene scores* DoF score66 X 51 X 5=168303 X 4 X 2=24
# samples 743
** MAII scorelog2(74/16830*10)=-4.507366095701
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/24*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ALB [Title/Abstract] AND ADH1C [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointALB(74272478)-ADH1C(100264212), # samples:2
Anticipated loss of major functional domain due to fusion event.ALB-ADH1C seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ALB-ADH1C seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ALB-ADH1C seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneALB

GO:0009267

cellular response to starvation

16245148

HgeneALB

GO:0043066

negative regulation of apoptotic process

16153637

HgeneALB

GO:0051659

maintenance of mitochondrion location

16153637

TgeneADH1C

GO:0006069

ethanol oxidation

6391957


check buttonFusion gene breakpoints across ALB (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ADH1C (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-DD-A1EJALBchr4

74272478

+ADH1Cchr4

100264212

-
ChimerDB4LIHCTCGA-DD-A1EJ-01AALBchr4

74272478

+ADH1Cchr4

100264212

-


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Fusion Gene ORF analysis for ALB-ADH1C

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000295897ENST00000515683ALBchr4

74272478

+ADH1Cchr4

100264212

-
5CDS-5UTRENST00000295897ENST00000510055ALBchr4

74272478

+ADH1Cchr4

100264212

-
intron-3CDSENST00000415165ENST00000515683ALBchr4

74272478

+ADH1Cchr4

100264212

-
intron-5UTRENST00000415165ENST00000510055ALBchr4

74272478

+ADH1Cchr4

100264212

-
Frame-shiftENST00000503124ENST00000515683ALBchr4

74272478

+ADH1Cchr4

100264212

-
5CDS-5UTRENST00000503124ENST00000510055ALBchr4

74272478

+ADH1Cchr4

100264212

-
In-frameENST00000509063ENST00000515683ALBchr4

74272478

+ADH1Cchr4

100264212

-
5CDS-5UTRENST00000509063ENST00000510055ALBchr4

74272478

+ADH1Cchr4

100264212

-
intron-3CDSENST00000401494ENST00000515683ALBchr4

74272478

+ADH1Cchr4

100264212

-
intron-5UTRENST00000401494ENST00000510055ALBchr4

74272478

+ADH1Cchr4

100264212

-
intron-3CDSENST00000505649ENST00000515683ALBchr4

74272478

+ADH1Cchr4

100264212

-
intron-5UTRENST00000505649ENST00000510055ALBchr4

74272478

+ADH1Cchr4

100264212

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000295897ALBchr474272478+ENST00000515683ADH1Cchr4100264212-118035962919285
ENST00000509063ALBchr474272478+ENST00000515683ADH1Cchr4100264212-111529424854276

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000295897ENST00000515683ALBchr474272478+ADH1Cchr4100264212-0.0004938990.9995061
ENST00000509063ENST00000515683ALBchr474272478+ADH1Cchr4100264212-0.0005528510.99944717

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Fusion Genomic Features for ALB-ADH1C


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ALB-ADH1C


check button Go to

FGviewer for the breakpoints of chr4:74272478-chr4:100264212

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ALB

P02768

ADH1C

P00326

FUNCTION: Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (PubMed:19021548). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017). Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017). {ECO:0000250|UniProtKB:P02769, ECO:0000269|PubMed:19021548, ECO:0000269|PubMed:6234017, ECO:0000305|PubMed:1630489}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneALBchr4:74272478chr4:100264212ENST00000295897+31519_21090.0661.0DomainAlbumin 1
HgeneALBchr4:74272478chr4:100264212ENST00000295897+315211_40390.0661.0DomainAlbumin 2
HgeneALBchr4:74272478chr4:100264212ENST00000295897+315404_60190.0661.0DomainAlbumin 3
HgeneALBchr4:74272478chr4:100264212ENST00000509063+31419_21090.0605.0DomainAlbumin 1
HgeneALBchr4:74272478chr4:100264212ENST00000509063+314211_40390.0605.0DomainAlbumin 2
HgeneALBchr4:74272478chr4:100264212ENST00000509063+314404_60190.0605.0DomainAlbumin 3


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Fusion Gene Sequence for ALB-ADH1C


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000295897_ENST00000515683_TCGA-DD-A1EJ_ALB_chr4_74272478_+_ADH1C_chr4_100264212_length(transcript)=1180nt_BP=359nt
AATTATTGGTTAAAGAAGTATATTAGTGCTAATTTCCCTCCGTTTGTCCTAGCTTTTCTCTTCTGTCAACCCCACACGCCTTTGGCACAA
TGAAGTGGGTAACCTTTATTTCCCTTCTTTTTCTCTTTAGCTCGGCTTATTCCAGGGGTGTGTTTCGTCGAGATGCACACAAGAGTGAGG
TTGCTCATCGGTTTAAAGATTTGGGAGAAGAAAATTTCAAAGCCTTGGTGTTGATTGCCTTTGCTCAGTATCTTCAGCAGTGTCCATTTG
AAGATCATGTAAAATTAGTGAATGAAGTAACTGAATTTGCAAAAACATGTGTTGCTGATGAGTCAGCTGAAAATTGTGACAAATCACTTG
TCACCCCAGGGTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGTTGTTATGGGCTGTAAAGCAGCTGGAGCAGCCAGAA
TCATTGCTGTGGACATCAACAAGGACAAATTTGCAAAGGCTAAAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTACAAGAAAC
CCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATGGCTTCCC
TGTTATGTTGTCATGAGGCATGTGGCACAAGTGTCATTGTAGGGGTACCTCCTGATTCCCAGAACCTCTCAATAAACCCTATGCTGCTAC
TGACTGGACGCACGTGGAAAGGAGCTATTTTTGGAGGCTTTAAGAGTAAAGAATCTGTCCCCAAACTTGTGGCTGACTTTATGGCTAAGA
AGTTTTCACTGGATGCATTAATAACAAATATTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCGCTCTGGAAAGAGTATCC
GTACCGTCCTGACGTTTTGAAACAATACAGATGCCTTCCCTTGTAGCAGTTTTCAGCCTCCTCTACCCTACATGATCTGGAGCAACAGCT
AGGAAATATCATTAATTCTGCTCTTCAGAGATGTTAAAAATAAATTACACGTGGGAGCTTTCCAAAGAAATGGAAATTGATGGGAAATTA
TTTGTCAAGCAAATGTTTAAAATCCAAATGAGAACTAAATAAAGTGTTGAACATCAACTGGGGAATTGAAGCCAATAAACCTTCCTTCTT

>In-frame_ENST00000295897_ENST00000515683_TCGA-DD-A1EJ_ALB_chr4_74272478_+_ADH1C_chr4_100264212_length(amino acids)=285AA_start in transcript=62_stop in transcript=919
MSTPHAFGTMKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADE
SAENCDKSLVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVI
GRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF

--------------------------------------------------------------
>In-frame_ENST00000509063_ENST00000515683_TCGA-DD-A1EJ_ALB_chr4_74272478_+_ADH1C_chr4_100264212_length(transcript)=1115nt_BP=294nt
TCAACCCCACACGCCTTTGGCACAATGAAGTGGGTAACCTTTATTTCCCTTCTTTTTCTCTTTAGCTCGGCTTATTCCAGGGGTGTGTTT
CGTCGAGATGCACACAAGAGTGAGGTTGCTCATCGGTTTAAAGATTTGGGAGAAGAAAATTTCAAAGCCTTGGTGTTGATTGCCTTTGCT
CAGTATCTTCAGCAGTGTCCATTTGAAGATCATGTAAAATTAGTGAATGAAGTAACTGAATTTGCAAAAACATGTGTTGCTGATGAGTCA
GCTGAAAATTGTGACAAATCACTTGTCACCCCAGGGTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGTTGTTATGGGC
TGTAAAGCAGCTGGAGCAGCCAGAATCATTGCTGTGGACATCAACAAGGACAAATTTGCAAAGGCTAAAGAGTTGGGTGCCACTGAATGC
ATCAACCCTCAAGACTACAAGAAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGT
CGGCTTGACACCATGATGGCTTCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGTGTCATTGTAGGGGTACCTCCTGATTCCCAGAAC
CTCTCAATAAACCCTATGCTGCTACTGACTGGACGCACGTGGAAAGGAGCTATTTTTGGAGGCTTTAAGAGTAAAGAATCTGTCCCCAAA
CTTGTGGCTGACTTTATGGCTAAGAAGTTTTCACTGGATGCATTAATAACAAATATTTTACCTTTTGAAAAAATAAATGAAGGATTTGAC
CTGCTTCGCTCTGGAAAGAGTATCCGTACCGTCCTGACGTTTTGAAACAATACAGATGCCTTCCCTTGTAGCAGTTTTCAGCCTCCTCTA
CCCTACATGATCTGGAGCAACAGCTAGGAAATATCATTAATTCTGCTCTTCAGAGATGTTAAAAATAAATTACACGTGGGAGCTTTCCAA
AGAAATGGAAATTGATGGGAAATTATTTGTCAAGCAAATGTTTAAAATCCAAATGAGAACTAAATAAAGTGTTGAACATCAACTGGGGAA

>In-frame_ENST00000509063_ENST00000515683_TCGA-DD-A1EJ_ALB_chr4_74272478_+_ADH1C_chr4_100264212_length(amino acids)=276AA_start in transcript=24_stop in transcript=854
MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSL
VTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMAS
LLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ALB-ADH1C


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ALB-ADH1C


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneALBP02768DB00493CefotaximeSmall moleculeApproved
HgeneALBP02768DB00493CefotaximeSmall moleculeApproved
HgeneALBP02768DB00493CefotaximeSmall moleculeApproved
HgeneALBP02768DB00493CefotaximeSmall moleculeApproved
HgeneALBP02768DB00493CefotaximeSmall moleculeApproved
HgeneALBP02768DB00493CefotaximeSmall moleculeApproved
HgeneALBP02768DB00493CefotaximeSmall moleculeApproved
HgeneALBP02768DB00493CefotaximeSmall moleculeApproved
HgeneALBP02768DB00493CefotaximeSmall moleculeApproved
HgeneALBP02768DB11359GuaiacolSmall moleculeApproved
HgeneALBP02768DB11359GuaiacolSmall moleculeApproved
HgeneALBP02768DB11359GuaiacolSmall moleculeApproved
HgeneALBP02768DB11359GuaiacolSmall moleculeApproved
HgeneALBP02768DB11359GuaiacolSmall moleculeApproved
HgeneALBP02768DB11359GuaiacolSmall moleculeApproved
HgeneALBP02768DB11359GuaiacolSmall moleculeApproved
HgeneALBP02768DB11359GuaiacolSmall moleculeApproved
HgeneALBP02768DB11359GuaiacolSmall moleculeApproved
HgeneALBP02768DB13967Patent BlueBinderSmall moleculeApproved
HgeneALBP02768DB13967Patent BlueBinderSmall moleculeApproved
HgeneALBP02768DB13967Patent BlueBinderSmall moleculeApproved
HgeneALBP02768DB13967Patent BlueBinderSmall moleculeApproved
HgeneALBP02768DB13967Patent BlueBinderSmall moleculeApproved
HgeneALBP02768DB13967Patent BlueBinderSmall moleculeApproved
HgeneALBP02768DB13967Patent BlueBinderSmall moleculeApproved
HgeneALBP02768DB13967Patent BlueBinderSmall moleculeApproved
HgeneALBP02768DB13967Patent BlueBinderSmall moleculeApproved
HgeneALBP02768DB03255PhenolSmall moleculeApproved|Experimental
HgeneALBP02768DB03255PhenolSmall moleculeApproved|Experimental
HgeneALBP02768DB03255PhenolSmall moleculeApproved|Experimental
HgeneALBP02768DB03255PhenolSmall moleculeApproved|Experimental
HgeneALBP02768DB03255PhenolSmall moleculeApproved|Experimental
HgeneALBP02768DB03255PhenolSmall moleculeApproved|Experimental
HgeneALBP02768DB03255PhenolSmall moleculeApproved|Experimental
HgeneALBP02768DB03255PhenolSmall moleculeApproved|Experimental
HgeneALBP02768DB03255PhenolSmall moleculeApproved|Experimental
HgeneALBP02768DB00276AmsacrineSmall moleculeApproved|Investigational
HgeneALBP02768DB00276AmsacrineSmall moleculeApproved|Investigational
HgeneALBP02768DB00276AmsacrineSmall moleculeApproved|Investigational
HgeneALBP02768DB00276AmsacrineSmall moleculeApproved|Investigational
HgeneALBP02768DB00276AmsacrineSmall moleculeApproved|Investigational
HgeneALBP02768DB00276AmsacrineSmall moleculeApproved|Investigational
HgeneALBP02768DB00276AmsacrineSmall moleculeApproved|Investigational
HgeneALBP02768DB00276AmsacrineSmall moleculeApproved|Investigational
HgeneALBP02768DB00276AmsacrineSmall moleculeApproved|Investigational
HgeneALBP02768DB00545PyridostigmineSmall moleculeApproved|Investigational
HgeneALBP02768DB00545PyridostigmineSmall moleculeApproved|Investigational
HgeneALBP02768DB00545PyridostigmineSmall moleculeApproved|Investigational
HgeneALBP02768DB00545PyridostigmineSmall moleculeApproved|Investigational
HgeneALBP02768DB00545PyridostigmineSmall moleculeApproved|Investigational
HgeneALBP02768DB00545PyridostigmineSmall moleculeApproved|Investigational
HgeneALBP02768DB00545PyridostigmineSmall moleculeApproved|Investigational
HgeneALBP02768DB00545PyridostigmineSmall moleculeApproved|Investigational
HgeneALBP02768DB00545PyridostigmineSmall moleculeApproved|Investigational
HgeneALBP02768DB06713NorelgestrominSmall moleculeApproved|Investigational
HgeneALBP02768DB06713NorelgestrominSmall moleculeApproved|Investigational
HgeneALBP02768DB06713NorelgestrominSmall moleculeApproved|Investigational
HgeneALBP02768DB06713NorelgestrominSmall moleculeApproved|Investigational
HgeneALBP02768DB06713NorelgestrominSmall moleculeApproved|Investigational
HgeneALBP02768DB06713NorelgestrominSmall moleculeApproved|Investigational
HgeneALBP02768DB06713NorelgestrominSmall moleculeApproved|Investigational
HgeneALBP02768DB06713NorelgestrominSmall moleculeApproved|Investigational
HgeneALBP02768DB06713NorelgestrominSmall moleculeApproved|Investigational
HgeneALBP02768DB12965SilverBinderSmall moleculeApproved|Investigational
HgeneALBP02768DB12965SilverBinderSmall moleculeApproved|Investigational
HgeneALBP02768DB12965SilverBinderSmall moleculeApproved|Investigational
HgeneALBP02768DB12965SilverBinderSmall moleculeApproved|Investigational
HgeneALBP02768DB12965SilverBinderSmall moleculeApproved|Investigational
HgeneALBP02768DB12965SilverBinderSmall moleculeApproved|Investigational
HgeneALBP02768DB12965SilverBinderSmall moleculeApproved|Investigational
HgeneALBP02768DB12965SilverBinderSmall moleculeApproved|Investigational
HgeneALBP02768DB12965SilverBinderSmall moleculeApproved|Investigational
TgeneADH1CP00326DB02659Cholic AcidSmall moleculeApproved
TgeneADH1CP00326DB02659Cholic AcidSmall moleculeApproved
TgeneADH1CP00326DB00157NADHSmall moleculeApproved|Nutraceutical
TgeneADH1CP00326DB00157NADHSmall moleculeApproved|Nutraceutical
TgeneADH1CP00326DB01213FomepizoleInhibitorSmall moleculeApproved|Vet_approved
TgeneADH1CP00326DB01213FomepizoleInhibitorSmall moleculeApproved|Vet_approved

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Related Diseases for ALB-ADH1C


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneALBC0033687Proteinuria9CTD_human
HgeneALBC0017658Glomerulonephritis8CTD_human
HgeneALBC0022658Kidney Diseases8CTD_human
HgeneALBC1704377Bright Disease8CTD_human
HgeneALBC0017665Membranous glomerulonephritis6CTD_human
HgeneALBC0027697Nephritis6CTD_human
HgeneALBC0086445Idiopathic Membranous Glomerulonephritis6CTD_human
HgeneALBC0342185Hyperthyroxinemia, Familial Dysalbuminemic6CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneALBC1704378Heymann Nephritis6CTD_human
HgeneALBC0022660Kidney Failure, Acute4CTD_human
HgeneALBC0027707Nephritis, Interstitial4CTD_human
HgeneALBC0038454Cerebrovascular accident4CTD_human
HgeneALBC0041349Nephritis, Tubulointerstitial4CTD_human
HgeneALBC0751956Acute Cerebrovascular Accidents4CTD_human
HgeneALBC1565662Acute Kidney Insufficiency4CTD_human
HgeneALBC2609414Acute kidney injury4CTD_human
HgeneALBC0023893Liver Cirrhosis, Experimental3CTD_human
HgeneALBC0025290Aseptic Meningitis3CTD_human
HgeneALBC0013221Drug toxicity2CTD_human
HgeneALBC0014544Epilepsy2CTD_human
HgeneALBC0019193Hepatitis, Toxic2CTD_human
HgeneALBC0020649Hypotension2CTD_human
HgeneALBC0023890Liver Cirrhosis2CTD_human
HgeneALBC0027726Nephrotic Syndrome2CTD_human
HgeneALBC0036830Serum Sickness2CTD_human
HgeneALBC0041755Adverse reaction to drug2CTD_human
HgeneALBC0086237Epilepsy, Cryptogenic2CTD_human
HgeneALBC0162557Liver Failure, Acute2CTD_human
HgeneALBC0236018Aura2CTD_human
HgeneALBC0239946Fibrosis, Liver2CTD_human
HgeneALBC0751111Awakening Epilepsy2CTD_human
HgeneALBC0860207Drug-Induced Liver Disease2CTD_human
HgeneALBC0878666Analbuminemia2ORPHANET
HgeneALBC1262760Hepatitis, Drug-Induced2CTD_human
HgeneALBC3658290Drug-Induced Acute Liver Injury2CTD_human
HgeneALBC4277682Chemical and Drug Induced Liver Injury2CTD_human
HgeneALBC4279912Chemically-Induced Liver Toxicity2CTD_human
HgeneALBC0002994Angioedema1CTD_human
HgeneALBC0003460Anuria1CTD_human
HgeneALBC0003865Arthritis, Adjuvant-Induced1CTD_human
HgeneALBC0004509Azoospermia1CTD_human
HgeneALBC0005398Cholestasis, Extrahepatic1CTD_human
HgeneALBC0006111Brain Diseases1CTD_human
HgeneALBC0007222Cardiovascular Diseases1CTD_human
HgeneALBC0007786Brain Ischemia1CTD_human
HgeneALBC0008312Primary biliary cirrhosis1CTD_human
HgeneALBC0011573Endogenous depression1CTD_human
HgeneALBC0011581Depressive disorder1CTD_human
HgeneALBC0011875Diabetic Angiopathies1CTD_human
HgeneALBC0011881Diabetic Nephropathy1CTD_human
HgeneALBC0013502Echinococcosis1CTD_human
HgeneALBC0014518Toxic Epidermal Necrolysis1CTD_human
HgeneALBC0016059Fibrosis1CTD_human
HgeneALBC0017662Glomerulonephritis, Membranoproliferative1CTD_human
HgeneALBC0017667Nodular glomerulosclerosis1CTD_human
HgeneALBC0018799Heart Diseases1CTD_human
HgeneALBC0018801Heart failure1CTD_human
HgeneALBC0018802Congestive heart failure1CTD_human
HgeneALBC0019061Hemolytic-Uremic Syndrome1CTD_human
HgeneALBC0019158Hepatitis1CTD_human
HgeneALBC0019209Hepatomegaly1CTD_human
HgeneALBC0019693HIV Infections1CTD_human
HgeneALBC0019699HIV Seropositivity1CTD_human
HgeneALBC0020517Hypersensitivity1CTD_human
HgeneALBC0020522Delayed Hypersensitivity1CTD_human
HgeneALBC0020538Hypertensive disease1CTD_human
HgeneALBC0022548Keloid1CTD_human
HgeneALBC0022661Kidney Failure, Chronic1CTD_human
HgeneALBC0023212Left-Sided Heart Failure1CTD_human
HgeneALBC0023892Biliary cirrhosis1CTD_human
HgeneALBC0024623Malignant neoplasm of stomach1CTD_human
HgeneALBC0025193Melancholia1CTD_human
HgeneALBC0025945Microangiopathy, Diabetic1CTD_human
HgeneALBC0026848Myopathy1CTD_human
HgeneALBC0027055Myocardial Reperfusion Injury1CTD_human
HgeneALBC0027720Nephrosis1CTD_human
HgeneALBC0028797Occupational Diseases1CTD_human
HgeneALBC0030193Pain1CTD_human
HgeneALBC0030286Pancreatic Diseases1CTD_human
HgeneALBC0030305Pancreatitis1CTD_human
HgeneALBC0035222Respiratory Distress Syndrome, Adult1CTD_human
HgeneALBC0035242Respiratory Tract Diseases1CTD_human
HgeneALBC0035457Rhinitis, Allergic, Perennial1CTD_human
HgeneALBC0038325Stevens-Johnson Syndrome1CTD_human
HgeneALBC0038356Stomach Neoplasms1CTD_human
HgeneALBC0040034Thrombocytopenia1CTD_human
HgeneALBC0041696Unipolar Depression1CTD_human
HgeneALBC0042109Urticaria1CTD_human
HgeneALBC0042164Uveitis1CTD_human
HgeneALBC0085584Encephalopathies1CTD_human
HgeneALBC0086133Depressive Syndrome1CTD_human
HgeneALBC0152013Adenocarcinoma of lung (disorder)1CTD_human
HgeneALBC0234230Pain, Burning1CTD_human
HgeneALBC0234238Ache1CTD_human
HgeneALBC0234254Radiating pain1CTD_human
HgeneALBC0235527Heart Failure, Right-Sided1CTD_human
HgeneALBC0238065Secondary Biliary Cholangitis1CTD_human
HgeneALBC0239981Hypoalbuminemia1CTD_human
HgeneALBC0268742Membranoproliferative Glomerulonephritis, Type I1CTD_human
HgeneALBC0268743Membranoproliferative Glomerulonephritis, Type II1CTD_human
HgeneALBC0273115Lung Injury1CTD_human
HgeneALBC0282126Depression, Neurotic1CTD_human
HgeneALBC0458257Pain, Splitting1CTD_human
HgeneALBC0458259Pain, Crushing1CTD_human
HgeneALBC0751407Pain, Migratory1CTD_human
HgeneALBC0751408Suffering, Physical1CTD_human
HgeneALBC0917798Cerebral Ischemia1CTD_human
HgeneALBC0971858Arthritis, Collagen-Induced1CTD_human
HgeneALBC0993582Arthritis, Experimental1CTD_human
HgeneALBC1274933Drug-Induced Stevens Johnson Syndrome1CTD_human
HgeneALBC1306571Hepatic Insufficiency1CTD_human
HgeneALBC1527304Allergic Reaction1CTD_human
HgeneALBC1623038Cirrhosis1CTD_human
HgeneALBC1708349Hereditary Diffuse Gastric Cancer1CTD_human
HgeneALBC1720821Membranoproliferative Glomerulonephritis, Type III1CTD_human
HgeneALBC1959583Myocardial Failure1CTD_human
HgeneALBC1961112Heart Decompensation1CTD_human
HgeneALBC2350344Chronic Lung Injury1CTD_human
HgeneALBC3658301Mycoplasma-Induced Stevens-Johnson Syndrome1CTD_human
HgeneALBC3658302Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum1CTD_human
HgeneALBC4505456HIV Coinfection1CTD_human
HgeneALBC4551595Biliary Cirrhosis, Primary, 11CTD_human
HgeneALBC4553297Cystic Echinocccosis1CTD_human
TgeneADH1CC0001973Alcoholic Intoxication, Chronic6CTD_human;PSYGENET
TgeneADH1CC0001969Alcoholic Intoxication5PSYGENET
TgeneADH1CC0085762Alcohol abuse5CTD_human;PSYGENET
TgeneADH1CC0001956Alcohol Use Disorder1CTD_human
TgeneADH1CC0026640Mouth Neoplasms1CTD_human
TgeneADH1CC0153381Malignant neoplasm of mouth1CTD_human