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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:INTS4-NARS2 (FusionGDB2 ID:39781)

Fusion Gene Summary for INTS4-NARS2

check button Fusion gene summary
Fusion gene informationFusion gene name: INTS4-NARS2
Fusion gene ID: 39781
HgeneTgene
Gene symbol

INTS4

NARS2

Gene ID

92105

79731

Gene nameintegrator complex subunit 4asparaginyl-tRNA synthetase 2, mitochondrial
SynonymsINT4|MST093DFNB94|SLM5|asnRS
Cytomap

11q14.1

11q14.1

Type of geneprotein-codingprotein-coding
Descriptionintegrator complex subunit 4MSTP093probable asparagine--tRNA ligase, mitochondrialasparagine tRNA ligase 2, mitochondrial (putative)asparaginyl-tRNA synthetase 2, mitochondrial (putative)deafness, autosomal recessive 94probable asparaginyl-tRNA synthetase, mitochondrial
Modification date2020031320200313
UniProtAcc

Q96HW7

Q96I59

Ensembl transtripts involved in fusion geneENST00000534064, ENST00000535943, 
ENST00000525931, ENST00000529807, 
ENST00000527522, 		ENST00000281038, 
ENST00000528850, 
Fusion gene scores* DoF score21 X 14 X 10=294029 X 15 X 11=4785
# samples 2937
** MAII scorelog2(29/2940*10)=-3.34169134970879
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(37/4785*10)=-3.69292174885708
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: INTS4 [Title/Abstract] AND NARS2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointINTS4(77666988)-NARS2(78177059), # samples:3
INTS4(77690042)-NARS2(78154804), # samples:3
NARS2(78239888)-INTS4(77590173), # samples:2
Anticipated loss of major functional domain due to fusion event.NARS2-INTS4 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
NARS2-INTS4 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneINTS4

GO:0016180

snRNA processing

16239144


check buttonFusion gene breakpoints across INTS4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across NARS2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-57-1993-01AINTS4chr11

77666988

-NARS2chr11

78177059

-
ChimerDB4STADTCGA-VQ-A928-01AINTS4chr11

77690042

-NARS2chr11

78154804

-
ChimerDB4STADTCGA-VQ-A928INTS4chr11

77690041

-NARS2chr11

78154804

-
ChimerDB4OVTCGA-57-1993-01AINTS4chr11

77666988

-NARS2chr11

78177059

-
ChimerDB4STADTCGA-VQ-A928-01AINTS4chr11

77690042

-NARS2chr11

78154804

-
ChimerDB4OVTCGA-57-1993-01AINTS4chr11

77666988

-NARS2chr11

78177059

-
ChimerDB4STADTCGA-VQ-A928-01AINTS4chr11

77690042

-NARS2chr11

78154804

-


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Fusion Gene ORF analysis for INTS4-NARS2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000534064ENST00000281038INTS4chr11

77666988

-NARS2chr11

78177059

-
In-frameENST00000534064ENST00000528850INTS4chr11

77666988

-NARS2chr11

78177059

-
intron-3CDSENST00000535943ENST00000281038INTS4chr11

77666988

-NARS2chr11

78177059

-
intron-3CDSENST00000535943ENST00000528850INTS4chr11

77666988

-NARS2chr11

78177059

-
intron-3CDSENST00000525931ENST00000281038INTS4chr11

77666988

-NARS2chr11

78177059

-
intron-3CDSENST00000525931ENST00000528850INTS4chr11

77666988

-NARS2chr11

78177059

-
In-frameENST00000529807ENST00000281038INTS4chr11

77666988

-NARS2chr11

78177059

-
In-frameENST00000529807ENST00000528850INTS4chr11

77666988

-NARS2chr11

78177059

-
intron-3CDSENST00000527522ENST00000281038INTS4chr11

77666988

-NARS2chr11

78177059

-
intron-3CDSENST00000527522ENST00000528850INTS4chr11

77666988

-NARS2chr11

78177059

-
In-frameENST00000534064ENST00000281038INTS4chr11

77690042

-NARS2chr11

78154804

-
In-frameENST00000534064ENST00000528850INTS4chr11

77690042

-NARS2chr11

78154804

-
intron-3CDSENST00000535943ENST00000281038INTS4chr11

77690042

-NARS2chr11

78154804

-
intron-3CDSENST00000535943ENST00000528850INTS4chr11

77690042

-NARS2chr11

78154804

-
intron-3CDSENST00000525931ENST00000281038INTS4chr11

77690042

-NARS2chr11

78154804

-
intron-3CDSENST00000525931ENST00000528850INTS4chr11

77690042

-NARS2chr11

78154804

-
In-frameENST00000529807ENST00000281038INTS4chr11

77690042

-NARS2chr11

78154804

-
In-frameENST00000529807ENST00000528850INTS4chr11

77690042

-NARS2chr11

78154804

-
intron-3CDSENST00000527522ENST00000281038INTS4chr11

77690042

-NARS2chr11

78154804

-
intron-3CDSENST00000527522ENST00000528850INTS4chr11

77690042

-NARS2chr11

78154804

-
In-frameENST00000534064ENST00000281038INTS4chr11

77690041

-NARS2chr11

78154804

-
In-frameENST00000534064ENST00000528850INTS4chr11

77690041

-NARS2chr11

78154804

-
intron-3CDSENST00000535943ENST00000281038INTS4chr11

77690041

-NARS2chr11

78154804

-
intron-3CDSENST00000535943ENST00000528850INTS4chr11

77690041

-NARS2chr11

78154804

-
intron-3CDSENST00000525931ENST00000281038INTS4chr11

77690041

-NARS2chr11

78154804

-
intron-3CDSENST00000525931ENST00000528850INTS4chr11

77690041

-NARS2chr11

78154804

-
In-frameENST00000529807ENST00000281038INTS4chr11

77690041

-NARS2chr11

78154804

-
In-frameENST00000529807ENST00000528850INTS4chr11

77690041

-NARS2chr11

78154804

-
intron-3CDSENST00000527522ENST00000281038INTS4chr11

77690041

-NARS2chr11

78154804

-
intron-3CDSENST00000527522ENST00000528850INTS4chr11

77690041

-NARS2chr11

78154804

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000534064INTS4chr1177666988-ENST00000281038NARS2chr1178177059-2070953351360441
ENST00000534064INTS4chr1177666988-ENST00000528850NARS2chr1178177059-1808953351360441
ENST00000529807INTS4chr1177666988-ENST00000281038NARS2chr1178177059-2058941231348441
ENST00000529807INTS4chr1177666988-ENST00000528850NARS2chr1178177059-1796941231348441
ENST00000534064INTS4chr1177690042-ENST00000281038NARS2chr1178154804-148550635775246
ENST00000534064INTS4chr1177690042-ENST00000528850NARS2chr1178154804-122350635775246
ENST00000529807INTS4chr1177690042-ENST00000281038NARS2chr1178154804-147349423763246
ENST00000529807INTS4chr1177690042-ENST00000528850NARS2chr1178154804-121149423763246
ENST00000534064INTS4chr1177690041-ENST00000281038NARS2chr1178154804-148550635775246
ENST00000534064INTS4chr1177690041-ENST00000528850NARS2chr1178154804-122350635775246
ENST00000529807INTS4chr1177690041-ENST00000281038NARS2chr1178154804-147349423763246
ENST00000529807INTS4chr1177690041-ENST00000528850NARS2chr1178154804-121149423763246

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000534064ENST00000281038INTS4chr1177666988-NARS2chr1178177059-0.0015885650.9984114
ENST00000534064ENST00000528850INTS4chr1177666988-NARS2chr1178177059-0.002897070.9971029
ENST00000529807ENST00000281038INTS4chr1177666988-NARS2chr1178177059-0.00161840.9983816
ENST00000529807ENST00000528850INTS4chr1177666988-NARS2chr1178177059-0.0029416660.9970584
ENST00000534064ENST00000281038INTS4chr1177690042-NARS2chr1178154804-0.0027121420.99728787
ENST00000534064ENST00000528850INTS4chr1177690042-NARS2chr1178154804-0.0031085770.99689144
ENST00000529807ENST00000281038INTS4chr1177690042-NARS2chr1178154804-0.0027951980.9972047
ENST00000529807ENST00000528850INTS4chr1177690042-NARS2chr1178154804-0.003056490.99694353
ENST00000534064ENST00000281038INTS4chr1177690041-NARS2chr1178154804-0.0027121420.99728787
ENST00000534064ENST00000528850INTS4chr1177690041-NARS2chr1178154804-0.0031085770.99689144
ENST00000529807ENST00000281038INTS4chr1177690041-NARS2chr1178154804-0.0027951980.9972047
ENST00000529807ENST00000528850INTS4chr1177690041-NARS2chr1178154804-0.003056490.99694353

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Fusion Genomic Features for INTS4-NARS2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for INTS4-NARS2


check button Go to

FGviewer for the breakpoints of chr11:77666988-chr11:78177059

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
INTS4

Q96HW7

NARS2

Q96I59

FUNCTION: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). {ECO:0000269|PubMed:23904267, ECO:0000305|PubMed:16239144}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneINTS4chr11:77666988chr11:78177059ENST00000529807-812145_183306.0506.0RepeatNote=HEAT 2
HgeneINTS4chr11:77666988chr11:78177059ENST00000529807-812190_228306.0506.0RepeatNote=HEAT 3
HgeneINTS4chr11:77666988chr11:78177059ENST00000529807-812229_263306.0506.0RepeatNote=HEAT 4
HgeneINTS4chr11:77666988chr11:78177059ENST00000529807-81266_105306.0506.0RepeatNote=HEAT 1
HgeneINTS4chr11:77666988chr11:78177059ENST00000534064-823145_183306.0964.0RepeatNote=HEAT 2
HgeneINTS4chr11:77666988chr11:78177059ENST00000534064-823190_228306.0964.0RepeatNote=HEAT 3
HgeneINTS4chr11:77666988chr11:78177059ENST00000534064-823229_263306.0964.0RepeatNote=HEAT 4
HgeneINTS4chr11:77666988chr11:78177059ENST00000534064-82366_105306.0964.0RepeatNote=HEAT 1
HgeneINTS4chr11:77690041chr11:78154804ENST00000529807-41266_105157.0506.0RepeatNote=HEAT 1
HgeneINTS4chr11:77690041chr11:78154804ENST00000534064-42366_105157.0964.0RepeatNote=HEAT 1
HgeneINTS4chr11:77690042chr11:78154804ENST00000529807-41266_105157.0506.0RepeatNote=HEAT 1
HgeneINTS4chr11:77690042chr11:78154804ENST00000534064-42366_105157.0964.0RepeatNote=HEAT 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneINTS4chr11:77666988chr11:78177059ENST00000529807-812277_313306.0506.0RepeatNote=HEAT 5
HgeneINTS4chr11:77666988chr11:78177059ENST00000529807-812369_405306.0506.0RepeatNote=HEAT 6
HgeneINTS4chr11:77666988chr11:78177059ENST00000529807-812406_444306.0506.0RepeatNote=HEAT 7
HgeneINTS4chr11:77666988chr11:78177059ENST00000529807-812446_484306.0506.0RepeatNote=HEAT 8
HgeneINTS4chr11:77666988chr11:78177059ENST00000534064-823277_313306.0964.0RepeatNote=HEAT 5
HgeneINTS4chr11:77666988chr11:78177059ENST00000534064-823369_405306.0964.0RepeatNote=HEAT 6
HgeneINTS4chr11:77666988chr11:78177059ENST00000534064-823406_444306.0964.0RepeatNote=HEAT 7
HgeneINTS4chr11:77666988chr11:78177059ENST00000534064-823446_484306.0964.0RepeatNote=HEAT 8
HgeneINTS4chr11:77666988chr11:78177059ENST00000535943-19145_1830339.0RepeatNote=HEAT 2
HgeneINTS4chr11:77666988chr11:78177059ENST00000535943-19190_2280339.0RepeatNote=HEAT 3
HgeneINTS4chr11:77666988chr11:78177059ENST00000535943-19229_2630339.0RepeatNote=HEAT 4
HgeneINTS4chr11:77666988chr11:78177059ENST00000535943-19277_3130339.0RepeatNote=HEAT 5
HgeneINTS4chr11:77666988chr11:78177059ENST00000535943-19369_4050339.0RepeatNote=HEAT 6
HgeneINTS4chr11:77666988chr11:78177059ENST00000535943-19406_4440339.0RepeatNote=HEAT 7
HgeneINTS4chr11:77666988chr11:78177059ENST00000535943-19446_4840339.0RepeatNote=HEAT 8
HgeneINTS4chr11:77666988chr11:78177059ENST00000535943-1966_1050339.0RepeatNote=HEAT 1
HgeneINTS4chr11:77690041chr11:78154804ENST00000529807-412145_183157.0506.0RepeatNote=HEAT 2
HgeneINTS4chr11:77690041chr11:78154804ENST00000529807-412190_228157.0506.0RepeatNote=HEAT 3
HgeneINTS4chr11:77690041chr11:78154804ENST00000529807-412229_263157.0506.0RepeatNote=HEAT 4
HgeneINTS4chr11:77690041chr11:78154804ENST00000529807-412277_313157.0506.0RepeatNote=HEAT 5
HgeneINTS4chr11:77690041chr11:78154804ENST00000529807-412369_405157.0506.0RepeatNote=HEAT 6
HgeneINTS4chr11:77690041chr11:78154804ENST00000529807-412406_444157.0506.0RepeatNote=HEAT 7
HgeneINTS4chr11:77690041chr11:78154804ENST00000529807-412446_484157.0506.0RepeatNote=HEAT 8
HgeneINTS4chr11:77690041chr11:78154804ENST00000534064-423145_183157.0964.0RepeatNote=HEAT 2
HgeneINTS4chr11:77690041chr11:78154804ENST00000534064-423190_228157.0964.0RepeatNote=HEAT 3
HgeneINTS4chr11:77690041chr11:78154804ENST00000534064-423229_263157.0964.0RepeatNote=HEAT 4
HgeneINTS4chr11:77690041chr11:78154804ENST00000534064-423277_313157.0964.0RepeatNote=HEAT 5
HgeneINTS4chr11:77690041chr11:78154804ENST00000534064-423369_405157.0964.0RepeatNote=HEAT 6
HgeneINTS4chr11:77690041chr11:78154804ENST00000534064-423406_444157.0964.0RepeatNote=HEAT 7
HgeneINTS4chr11:77690041chr11:78154804ENST00000534064-423446_484157.0964.0RepeatNote=HEAT 8
HgeneINTS4chr11:77690041chr11:78154804ENST00000535943-19145_1830339.0RepeatNote=HEAT 2
HgeneINTS4chr11:77690041chr11:78154804ENST00000535943-19190_2280339.0RepeatNote=HEAT 3
HgeneINTS4chr11:77690041chr11:78154804ENST00000535943-19229_2630339.0RepeatNote=HEAT 4
HgeneINTS4chr11:77690041chr11:78154804ENST00000535943-19277_3130339.0RepeatNote=HEAT 5
HgeneINTS4chr11:77690041chr11:78154804ENST00000535943-19369_4050339.0RepeatNote=HEAT 6
HgeneINTS4chr11:77690041chr11:78154804ENST00000535943-19406_4440339.0RepeatNote=HEAT 7
HgeneINTS4chr11:77690041chr11:78154804ENST00000535943-19446_4840339.0RepeatNote=HEAT 8
HgeneINTS4chr11:77690041chr11:78154804ENST00000535943-1966_1050339.0RepeatNote=HEAT 1
HgeneINTS4chr11:77690042chr11:78154804ENST00000529807-412145_183157.0506.0RepeatNote=HEAT 2
HgeneINTS4chr11:77690042chr11:78154804ENST00000529807-412190_228157.0506.0RepeatNote=HEAT 3
HgeneINTS4chr11:77690042chr11:78154804ENST00000529807-412229_263157.0506.0RepeatNote=HEAT 4
HgeneINTS4chr11:77690042chr11:78154804ENST00000529807-412277_313157.0506.0RepeatNote=HEAT 5
HgeneINTS4chr11:77690042chr11:78154804ENST00000529807-412369_405157.0506.0RepeatNote=HEAT 6
HgeneINTS4chr11:77690042chr11:78154804ENST00000529807-412406_444157.0506.0RepeatNote=HEAT 7
HgeneINTS4chr11:77690042chr11:78154804ENST00000529807-412446_484157.0506.0RepeatNote=HEAT 8
HgeneINTS4chr11:77690042chr11:78154804ENST00000534064-423145_183157.0964.0RepeatNote=HEAT 2
HgeneINTS4chr11:77690042chr11:78154804ENST00000534064-423190_228157.0964.0RepeatNote=HEAT 3
HgeneINTS4chr11:77690042chr11:78154804ENST00000534064-423229_263157.0964.0RepeatNote=HEAT 4
HgeneINTS4chr11:77690042chr11:78154804ENST00000534064-423277_313157.0964.0RepeatNote=HEAT 5
HgeneINTS4chr11:77690042chr11:78154804ENST00000534064-423369_405157.0964.0RepeatNote=HEAT 6
HgeneINTS4chr11:77690042chr11:78154804ENST00000534064-423406_444157.0964.0RepeatNote=HEAT 7
HgeneINTS4chr11:77690042chr11:78154804ENST00000534064-423446_484157.0964.0RepeatNote=HEAT 8
HgeneINTS4chr11:77690042chr11:78154804ENST00000535943-19145_1830339.0RepeatNote=HEAT 2
HgeneINTS4chr11:77690042chr11:78154804ENST00000535943-19190_2280339.0RepeatNote=HEAT 3
HgeneINTS4chr11:77690042chr11:78154804ENST00000535943-19229_2630339.0RepeatNote=HEAT 4
HgeneINTS4chr11:77690042chr11:78154804ENST00000535943-19277_3130339.0RepeatNote=HEAT 5
HgeneINTS4chr11:77690042chr11:78154804ENST00000535943-19369_4050339.0RepeatNote=HEAT 6
HgeneINTS4chr11:77690042chr11:78154804ENST00000535943-19406_4440339.0RepeatNote=HEAT 7
HgeneINTS4chr11:77690042chr11:78154804ENST00000535943-19446_4840339.0RepeatNote=HEAT 8
HgeneINTS4chr11:77690042chr11:78154804ENST00000535943-1966_1050339.0RepeatNote=HEAT 1


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Fusion Gene Sequence for INTS4-NARS2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000534064_ENST00000281038_TCGA-57-1993-01A_INTS4_chr11_77666988_-_NARS2_chr11_78177059_length(transcript)=2070nt_BP=953nt
TAGTGTACGGAAGCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGC
CACAGGAGGAAATTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCC
CAGCAGATGCTTTGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAAC
ATTATTACAAGGAGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACT
GCATTATGGATGATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCA
CTAAGCTACCAGAGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGCATCTGACAGATACGTCTCATGGTGTAAGAAATA
AGTGCCTGCAGTTACTTGGCAATCTTGGCTCTTTGGAGAAAAGTGTCACAAAAGATGCAGAAGGCCTAGCTGCCAGAGATGTCCAGAAGA
TTATAGGGGATTACTTCAGTGACCAAGACCCACGTGTCAGAACAGCAGCTATAAAAGCCATGTTGCAGCTCCATGAAAGAGGACTGAAAT
TACACCAAACAATTTATAATCAGGCCTGTAAATTACTCTCTGATGACTATGAACAAGTGCGCAGTGCTGCAGTCCAGCTTATCTGGGTCG
TCAGTCAGCTCTATCCTGAAAGCATTGTCCCAATTCCTTCTTCTAATGAAGAAATACGCTTAGTTGATGATGCGTTTGGCAAAATTTGTC
ACATGGTCAGTGATGGCTCTTGGGTGGTTCGTGTTCAGGCAGCAAAACTGTTGTGGGGTGCTGACCTACGGACTGAACATGAAAAGTACC
TGGTGAAGCACTGTGGCAACATACCTGTCTTCGTTATTAATTATCCATTAACACTCAAGCCTTTCTACATGAGGGATAATGAAGATGGCC
CTCAGCACACGGTTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTGGGGAACTCTTTGGAGGAGGCCTCAGAGAAGAACGATACCATTTCT
TAGAGGAGCGCTTAGCCAGATCGGGACTTACAGAAGTCTACCAATGGTATCTGGACCTTCGTCGATTTGGATCTGTGCCACATGGAGGTT
TTGGGATGGGATTTGAACGCTACCTGCAGTGCATCTTGGGTGTTGACAATATCAAAGATGTTATCCCTTTCCCAAGGTTTCCTCATTCAT
GCCTTTTATAGCTGGAAGATTGGTTAAGGAAAAGCACCCCCCATGGCAGAGACACTGCACATGATTGTGCATACAGCAGAATGCATGTTT
GGATTTTAGAAATGCAGATTTCAATATGTAATTGTTGTGCCATAAGATATCATAGAAAAAATATAAGTGGTTGTGATTTTCTTAGAAAGT
TGAGGGTATTTCACGTAAGGATGAGCTCCCGCAAGAAGAGGTACTTATAGCAAGGGGACTCTCAAATCCATTACCTCAATTAAGAAATGA
AGAAATTGAATTAGTCTCAAAGTTTCTTTTAAACTCTAAAACAGAATGAGATAATGTATTTTACGTTGTCTATAATCATTAAATCACTCC
CTGTGTAATTTGTGAGAACCATCTAGTAGCTCGAAATAAAATAATGTTGCATCTTTTCTCCCTTGCCATATACTTTGTGATAAATCCTTA
TCTCATTTTCAGTACTTCATTAAACATTGCAGAAAAAAATATTCCTTAAGGTCTTAATTGATTTAAAGAAGTAGCTATTCTGAATTGAAA
TCTCCTTTCATTGAACTGGATGAAAAAATCATGTTTAATAACTGTTGCTTTTCAATTTTCAAAGCTGTTGAGATATTACATTAAGTATTT
CAACTCTTTAATCACTGTTGTTATAATTTGTTTATATTTGATGTTTATAATTTGTCTAATAAAATAGATTTTTTTAATAGACACCTATGG

>In-frame_ENST00000534064_ENST00000281038_TCGA-57-1993-01A_INTS4_chr11_77666988_-_NARS2_chr11_78177059_length(amino acids)=441AA_start in transcript=35_stop in transcript=1360
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSL
EKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPI
PSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLWGADLRTEHEKYLVKHCGNIPVFVINYPLTLKPFYMRDNEDGPQHTVAAVDLLV

--------------------------------------------------------------
>In-frame_ENST00000534064_ENST00000528850_TCGA-57-1993-01A_INTS4_chr11_77666988_-_NARS2_chr11_78177059_length(transcript)=1808nt_BP=953nt
TAGTGTACGGAAGCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGC
CACAGGAGGAAATTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCC
CAGCAGATGCTTTGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAAC
ATTATTACAAGGAGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACT
GCATTATGGATGATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCA
CTAAGCTACCAGAGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGCATCTGACAGATACGTCTCATGGTGTAAGAAATA
AGTGCCTGCAGTTACTTGGCAATCTTGGCTCTTTGGAGAAAAGTGTCACAAAAGATGCAGAAGGCCTAGCTGCCAGAGATGTCCAGAAGA
TTATAGGGGATTACTTCAGTGACCAAGACCCACGTGTCAGAACAGCAGCTATAAAAGCCATGTTGCAGCTCCATGAAAGAGGACTGAAAT
TACACCAAACAATTTATAATCAGGCCTGTAAATTACTCTCTGATGACTATGAACAAGTGCGCAGTGCTGCAGTCCAGCTTATCTGGGTCG
TCAGTCAGCTCTATCCTGAAAGCATTGTCCCAATTCCTTCTTCTAATGAAGAAATACGCTTAGTTGATGATGCGTTTGGCAAAATTTGTC
ACATGGTCAGTGATGGCTCTTGGGTGGTTCGTGTTCAGGCAGCAAAACTGTTGTGGGGTGCTGACCTACGGACTGAACATGAAAAGTACC
TGGTGAAGCACTGTGGCAACATACCTGTCTTCGTTATTAATTATCCATTAACACTCAAGCCTTTCTACATGAGGGATAATGAAGATGGCC
CTCAGCACACGGTTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTGGGGAACTCTTTGGAGGAGGCCTCAGAGAAGAACGATACCATTTCT
TAGAGGAGCGCTTAGCCAGATCGGGACTTACAGAAGTCTACCAATGGTATCTGGACCTTCGTCGATTTGGATCTGTGCCACATGGAGGTT
TTGGGATGGGATTTGAACGCTACCTGCAGTGCATCTTGGGTGTTGACAATATCAAAGATGTTATCCCTTTCCCAAGGTTTCCTCATTCAT
GCCTTTTATAGCTGGAAGATTGGTTAAGGAAAAGCACCCCCCATGGCAGAGACACTGCACATGATTGTGCATACAGCAGAATGCATGTTT
GGATTTTAGAAATGCAGATTTCAATATGTAATTGTTGTGCCATAAGATATCATAGAAAAAATATAAGTGGTTGTGATTTTCTTAGAAAGT
TGAGGGTATTTCACGTAAGGATGAGCTCCCGCAAGAAGAGGTACTTATAGCAAGGGGACTCTCAAATCCATTACCTCAATTAAGAAATGA
AGAAATTGAATTAGTCTCAAAGTTTCTTTTAAACTCTAAAACAGAATGAGATAATGTATTTTACGTTGTCTATAATCATTAAATCACTCC
CTGTGTAATTTGTGAGAACCATCTAGTAGCTCGAAATAAAATAATGTTGCATCTTTTCTCCCTTGCCATATACTTTGTGATAAATCCTTA

>In-frame_ENST00000534064_ENST00000528850_TCGA-57-1993-01A_INTS4_chr11_77666988_-_NARS2_chr11_78177059_length(amino acids)=441AA_start in transcript=35_stop in transcript=1360
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSL
EKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPI
PSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLWGADLRTEHEKYLVKHCGNIPVFVINYPLTLKPFYMRDNEDGPQHTVAAVDLLV

--------------------------------------------------------------
>In-frame_ENST00000529807_ENST00000281038_TCGA-57-1993-01A_INTS4_chr11_77666988_-_NARS2_chr11_78177059_length(transcript)=2058nt_BP=941nt
GCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGCCACAGGAGGAAA
TTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCCCAGCAGATGCTT
TGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAACATTATTACAAGG
AGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACTGCATTATGGATG
ATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCACTAAGCTACCAG
AGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGCATCTGACAGATACGTCTCATGGTGTAAGAAATAAGTGCCTGCAGT
TACTTGGCAATCTTGGCTCTTTGGAGAAAAGTGTCACAAAAGATGCAGAAGGCCTAGCTGCCAGAGATGTCCAGAAGATTATAGGGGATT
ACTTCAGTGACCAAGACCCACGTGTCAGAACAGCAGCTATAAAAGCCATGTTGCAGCTCCATGAAAGAGGACTGAAATTACACCAAACAA
TTTATAATCAGGCCTGTAAATTACTCTCTGATGACTATGAACAAGTGCGCAGTGCTGCAGTCCAGCTTATCTGGGTCGTCAGTCAGCTCT
ATCCTGAAAGCATTGTCCCAATTCCTTCTTCTAATGAAGAAATACGCTTAGTTGATGATGCGTTTGGCAAAATTTGTCACATGGTCAGTG
ATGGCTCTTGGGTGGTTCGTGTTCAGGCAGCAAAACTGTTGTGGGGTGCTGACCTACGGACTGAACATGAAAAGTACCTGGTGAAGCACT
GTGGCAACATACCTGTCTTCGTTATTAATTATCCATTAACACTCAAGCCTTTCTACATGAGGGATAATGAAGATGGCCCTCAGCACACGG
TTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTGGGGAACTCTTTGGAGGAGGCCTCAGAGAAGAACGATACCATTTCTTAGAGGAGCGCT
TAGCCAGATCGGGACTTACAGAAGTCTACCAATGGTATCTGGACCTTCGTCGATTTGGATCTGTGCCACATGGAGGTTTTGGGATGGGAT
TTGAACGCTACCTGCAGTGCATCTTGGGTGTTGACAATATCAAAGATGTTATCCCTTTCCCAAGGTTTCCTCATTCATGCCTTTTATAGC
TGGAAGATTGGTTAAGGAAAAGCACCCCCCATGGCAGAGACACTGCACATGATTGTGCATACAGCAGAATGCATGTTTGGATTTTAGAAA
TGCAGATTTCAATATGTAATTGTTGTGCCATAAGATATCATAGAAAAAATATAAGTGGTTGTGATTTTCTTAGAAAGTTGAGGGTATTTC
ACGTAAGGATGAGCTCCCGCAAGAAGAGGTACTTATAGCAAGGGGACTCTCAAATCCATTACCTCAATTAAGAAATGAAGAAATTGAATT
AGTCTCAAAGTTTCTTTTAAACTCTAAAACAGAATGAGATAATGTATTTTACGTTGTCTATAATCATTAAATCACTCCCTGTGTAATTTG
TGAGAACCATCTAGTAGCTCGAAATAAAATAATGTTGCATCTTTTCTCCCTTGCCATATACTTTGTGATAAATCCTTATCTCATTTTCAG
TACTTCATTAAACATTGCAGAAAAAAATATTCCTTAAGGTCTTAATTGATTTAAAGAAGTAGCTATTCTGAATTGAAATCTCCTTTCATT
GAACTGGATGAAAAAATCATGTTTAATAACTGTTGCTTTTCAATTTTCAAAGCTGTTGAGATATTACATTAAGTATTTCAACTCTTTAAT

>In-frame_ENST00000529807_ENST00000281038_TCGA-57-1993-01A_INTS4_chr11_77666988_-_NARS2_chr11_78177059_length(amino acids)=441AA_start in transcript=23_stop in transcript=1348
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSL
EKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPI
PSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLWGADLRTEHEKYLVKHCGNIPVFVINYPLTLKPFYMRDNEDGPQHTVAAVDLLV

--------------------------------------------------------------
>In-frame_ENST00000529807_ENST00000528850_TCGA-57-1993-01A_INTS4_chr11_77666988_-_NARS2_chr11_78177059_length(transcript)=1796nt_BP=941nt
GCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGCCACAGGAGGAAA
TTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCCCAGCAGATGCTT
TGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAACATTATTACAAGG
AGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACTGCATTATGGATG
ATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCACTAAGCTACCAG
AGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGCATCTGACAGATACGTCTCATGGTGTAAGAAATAAGTGCCTGCAGT
TACTTGGCAATCTTGGCTCTTTGGAGAAAAGTGTCACAAAAGATGCAGAAGGCCTAGCTGCCAGAGATGTCCAGAAGATTATAGGGGATT
ACTTCAGTGACCAAGACCCACGTGTCAGAACAGCAGCTATAAAAGCCATGTTGCAGCTCCATGAAAGAGGACTGAAATTACACCAAACAA
TTTATAATCAGGCCTGTAAATTACTCTCTGATGACTATGAACAAGTGCGCAGTGCTGCAGTCCAGCTTATCTGGGTCGTCAGTCAGCTCT
ATCCTGAAAGCATTGTCCCAATTCCTTCTTCTAATGAAGAAATACGCTTAGTTGATGATGCGTTTGGCAAAATTTGTCACATGGTCAGTG
ATGGCTCTTGGGTGGTTCGTGTTCAGGCAGCAAAACTGTTGTGGGGTGCTGACCTACGGACTGAACATGAAAAGTACCTGGTGAAGCACT
GTGGCAACATACCTGTCTTCGTTATTAATTATCCATTAACACTCAAGCCTTTCTACATGAGGGATAATGAAGATGGCCCTCAGCACACGG
TTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTGGGGAACTCTTTGGAGGAGGCCTCAGAGAAGAACGATACCATTTCTTAGAGGAGCGCT
TAGCCAGATCGGGACTTACAGAAGTCTACCAATGGTATCTGGACCTTCGTCGATTTGGATCTGTGCCACATGGAGGTTTTGGGATGGGAT
TTGAACGCTACCTGCAGTGCATCTTGGGTGTTGACAATATCAAAGATGTTATCCCTTTCCCAAGGTTTCCTCATTCATGCCTTTTATAGC
TGGAAGATTGGTTAAGGAAAAGCACCCCCCATGGCAGAGACACTGCACATGATTGTGCATACAGCAGAATGCATGTTTGGATTTTAGAAA
TGCAGATTTCAATATGTAATTGTTGTGCCATAAGATATCATAGAAAAAATATAAGTGGTTGTGATTTTCTTAGAAAGTTGAGGGTATTTC
ACGTAAGGATGAGCTCCCGCAAGAAGAGGTACTTATAGCAAGGGGACTCTCAAATCCATTACCTCAATTAAGAAATGAAGAAATTGAATT
AGTCTCAAAGTTTCTTTTAAACTCTAAAACAGAATGAGATAATGTATTTTACGTTGTCTATAATCATTAAATCACTCCCTGTGTAATTTG

>In-frame_ENST00000529807_ENST00000528850_TCGA-57-1993-01A_INTS4_chr11_77666988_-_NARS2_chr11_78177059_length(amino acids)=441AA_start in transcript=23_stop in transcript=1348
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSL
EKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPI
PSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLWGADLRTEHEKYLVKHCGNIPVFVINYPLTLKPFYMRDNEDGPQHTVAAVDLLV

--------------------------------------------------------------
>In-frame_ENST00000534064_ENST00000281038_TCGA-VQ-A928-01A_INTS4_chr11_77690042_-_NARS2_chr11_78154804_length(transcript)=1485nt_BP=506nt
TAGTGTACGGAAGCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGC
CACAGGAGGAAATTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCC
CAGCAGATGCTTTGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAAC
ATTATTACAAGGAGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACT
GCATTATGGATGATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCA
CTAAGCTACCAGAGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGGTTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTG
GGGAACTCTTTGGAGGAGGCCTCAGAGAAGAACGATACCATTTCTTAGAGGAGCGCTTAGCCAGATCGGGACTTACAGAAGTCTACCAAT
GGTATCTGGACCTTCGTCGATTTGGATCTGTGCCACATGGAGGTTTTGGGATGGGATTTGAACGCTACCTGCAGTGCATCTTGGGTGTTG
ACAATATCAAAGATGTTATCCCTTTCCCAAGGTTTCCTCATTCATGCCTTTTATAGCTGGAAGATTGGTTAAGGAAAAGCACCCCCCATG
GCAGAGACACTGCACATGATTGTGCATACAGCAGAATGCATGTTTGGATTTTAGAAATGCAGATTTCAATATGTAATTGTTGTGCCATAA
GATATCATAGAAAAAATATAAGTGGTTGTGATTTTCTTAGAAAGTTGAGGGTATTTCACGTAAGGATGAGCTCCCGCAAGAAGAGGTACT
TATAGCAAGGGGACTCTCAAATCCATTACCTCAATTAAGAAATGAAGAAATTGAATTAGTCTCAAAGTTTCTTTTAAACTCTAAAACAGA
ATGAGATAATGTATTTTACGTTGTCTATAATCATTAAATCACTCCCTGTGTAATTTGTGAGAACCATCTAGTAGCTCGAAATAAAATAAT
GTTGCATCTTTTCTCCCTTGCCATATACTTTGTGATAAATCCTTATCTCATTTTCAGTACTTCATTAAACATTGCAGAAAAAAATATTCC
TTAAGGTCTTAATTGATTTAAAGAAGTAGCTATTCTGAATTGAAATCTCCTTTCATTGAACTGGATGAAAAAATCATGTTTAATAACTGT
TGCTTTTCAATTTTCAAAGCTGTTGAGATATTACATTAAGTATTTCAACTCTTTAATCACTGTTGTTATAATTTGTTTATATTTGATGTT

>In-frame_ENST00000534064_ENST00000281038_TCGA-VQ-A928-01A_INTS4_chr11_77690042_-_NARS2_chr11_78154804_length(amino acids)=246AA_start in transcript=35_stop in transcript=775
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKVAAVDLLVPGVGELFGGGLREER

--------------------------------------------------------------
>In-frame_ENST00000534064_ENST00000528850_TCGA-VQ-A928-01A_INTS4_chr11_77690042_-_NARS2_chr11_78154804_length(transcript)=1223nt_BP=506nt
TAGTGTACGGAAGCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGC
CACAGGAGGAAATTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCC
CAGCAGATGCTTTGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAAC
ATTATTACAAGGAGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACT
GCATTATGGATGATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCA
CTAAGCTACCAGAGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGGTTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTG
GGGAACTCTTTGGAGGAGGCCTCAGAGAAGAACGATACCATTTCTTAGAGGAGCGCTTAGCCAGATCGGGACTTACAGAAGTCTACCAAT
GGTATCTGGACCTTCGTCGATTTGGATCTGTGCCACATGGAGGTTTTGGGATGGGATTTGAACGCTACCTGCAGTGCATCTTGGGTGTTG
ACAATATCAAAGATGTTATCCCTTTCCCAAGGTTTCCTCATTCATGCCTTTTATAGCTGGAAGATTGGTTAAGGAAAAGCACCCCCCATG
GCAGAGACACTGCACATGATTGTGCATACAGCAGAATGCATGTTTGGATTTTAGAAATGCAGATTTCAATATGTAATTGTTGTGCCATAA
GATATCATAGAAAAAATATAAGTGGTTGTGATTTTCTTAGAAAGTTGAGGGTATTTCACGTAAGGATGAGCTCCCGCAAGAAGAGGTACT
TATAGCAAGGGGACTCTCAAATCCATTACCTCAATTAAGAAATGAAGAAATTGAATTAGTCTCAAAGTTTCTTTTAAACTCTAAAACAGA
ATGAGATAATGTATTTTACGTTGTCTATAATCATTAAATCACTCCCTGTGTAATTTGTGAGAACCATCTAGTAGCTCGAAATAAAATAAT

>In-frame_ENST00000534064_ENST00000528850_TCGA-VQ-A928-01A_INTS4_chr11_77690042_-_NARS2_chr11_78154804_length(amino acids)=246AA_start in transcript=35_stop in transcript=775
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKVAAVDLLVPGVGELFGGGLREER

--------------------------------------------------------------
>In-frame_ENST00000529807_ENST00000281038_TCGA-VQ-A928-01A_INTS4_chr11_77690042_-_NARS2_chr11_78154804_length(transcript)=1473nt_BP=494nt
GCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGCCACAGGAGGAAA
TTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCCCAGCAGATGCTT
TGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAACATTATTACAAGG
AGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACTGCATTATGGATG
ATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCACTAAGCTACCAG
AGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGGTTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTGGGGAACTCTTTG
GAGGAGGCCTCAGAGAAGAACGATACCATTTCTTAGAGGAGCGCTTAGCCAGATCGGGACTTACAGAAGTCTACCAATGGTATCTGGACC
TTCGTCGATTTGGATCTGTGCCACATGGAGGTTTTGGGATGGGATTTGAACGCTACCTGCAGTGCATCTTGGGTGTTGACAATATCAAAG
ATGTTATCCCTTTCCCAAGGTTTCCTCATTCATGCCTTTTATAGCTGGAAGATTGGTTAAGGAAAAGCACCCCCCATGGCAGAGACACTG
CACATGATTGTGCATACAGCAGAATGCATGTTTGGATTTTAGAAATGCAGATTTCAATATGTAATTGTTGTGCCATAAGATATCATAGAA
AAAATATAAGTGGTTGTGATTTTCTTAGAAAGTTGAGGGTATTTCACGTAAGGATGAGCTCCCGCAAGAAGAGGTACTTATAGCAAGGGG
ACTCTCAAATCCATTACCTCAATTAAGAAATGAAGAAATTGAATTAGTCTCAAAGTTTCTTTTAAACTCTAAAACAGAATGAGATAATGT
ATTTTACGTTGTCTATAATCATTAAATCACTCCCTGTGTAATTTGTGAGAACCATCTAGTAGCTCGAAATAAAATAATGTTGCATCTTTT
CTCCCTTGCCATATACTTTGTGATAAATCCTTATCTCATTTTCAGTACTTCATTAAACATTGCAGAAAAAAATATTCCTTAAGGTCTTAA
TTGATTTAAAGAAGTAGCTATTCTGAATTGAAATCTCCTTTCATTGAACTGGATGAAAAAATCATGTTTAATAACTGTTGCTTTTCAATT
TTCAAAGCTGTTGAGATATTACATTAAGTATTTCAACTCTTTAATCACTGTTGTTATAATTTGTTTATATTTGATGTTTATAATTTGTCT

>In-frame_ENST00000529807_ENST00000281038_TCGA-VQ-A928-01A_INTS4_chr11_77690042_-_NARS2_chr11_78154804_length(amino acids)=246AA_start in transcript=23_stop in transcript=763
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKVAAVDLLVPGVGELFGGGLREER

--------------------------------------------------------------
>In-frame_ENST00000529807_ENST00000528850_TCGA-VQ-A928-01A_INTS4_chr11_77690042_-_NARS2_chr11_78154804_length(transcript)=1211nt_BP=494nt
GCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGCCACAGGAGGAAA
TTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCCCAGCAGATGCTT
TGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAACATTATTACAAGG
AGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACTGCATTATGGATG
ATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCACTAAGCTACCAG
AGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGGTTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTGGGGAACTCTTTG
GAGGAGGCCTCAGAGAAGAACGATACCATTTCTTAGAGGAGCGCTTAGCCAGATCGGGACTTACAGAAGTCTACCAATGGTATCTGGACC
TTCGTCGATTTGGATCTGTGCCACATGGAGGTTTTGGGATGGGATTTGAACGCTACCTGCAGTGCATCTTGGGTGTTGACAATATCAAAG
ATGTTATCCCTTTCCCAAGGTTTCCTCATTCATGCCTTTTATAGCTGGAAGATTGGTTAAGGAAAAGCACCCCCCATGGCAGAGACACTG
CACATGATTGTGCATACAGCAGAATGCATGTTTGGATTTTAGAAATGCAGATTTCAATATGTAATTGTTGTGCCATAAGATATCATAGAA
AAAATATAAGTGGTTGTGATTTTCTTAGAAAGTTGAGGGTATTTCACGTAAGGATGAGCTCCCGCAAGAAGAGGTACTTATAGCAAGGGG
ACTCTCAAATCCATTACCTCAATTAAGAAATGAAGAAATTGAATTAGTCTCAAAGTTTCTTTTAAACTCTAAAACAGAATGAGATAATGT
ATTTTACGTTGTCTATAATCATTAAATCACTCCCTGTGTAATTTGTGAGAACCATCTAGTAGCTCGAAATAAAATAATGTTGCATCTTTT

>In-frame_ENST00000529807_ENST00000528850_TCGA-VQ-A928-01A_INTS4_chr11_77690042_-_NARS2_chr11_78154804_length(amino acids)=246AA_start in transcript=23_stop in transcript=763
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKVAAVDLLVPGVGELFGGGLREER

--------------------------------------------------------------
>In-frame_ENST00000534064_ENST00000281038_TCGA-VQ-A928_INTS4_chr11_77690041_-_NARS2_chr11_78154804_length(transcript)=1485nt_BP=506nt
TAGTGTACGGAAGCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGC
CACAGGAGGAAATTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCC
CAGCAGATGCTTTGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAAC
ATTATTACAAGGAGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACT
GCATTATGGATGATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCA
CTAAGCTACCAGAGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGGTTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTG
GGGAACTCTTTGGAGGAGGCCTCAGAGAAGAACGATACCATTTCTTAGAGGAGCGCTTAGCCAGATCGGGACTTACAGAAGTCTACCAAT
GGTATCTGGACCTTCGTCGATTTGGATCTGTGCCACATGGAGGTTTTGGGATGGGATTTGAACGCTACCTGCAGTGCATCTTGGGTGTTG
ACAATATCAAAGATGTTATCCCTTTCCCAAGGTTTCCTCATTCATGCCTTTTATAGCTGGAAGATTGGTTAAGGAAAAGCACCCCCCATG
GCAGAGACACTGCACATGATTGTGCATACAGCAGAATGCATGTTTGGATTTTAGAAATGCAGATTTCAATATGTAATTGTTGTGCCATAA
GATATCATAGAAAAAATATAAGTGGTTGTGATTTTCTTAGAAAGTTGAGGGTATTTCACGTAAGGATGAGCTCCCGCAAGAAGAGGTACT
TATAGCAAGGGGACTCTCAAATCCATTACCTCAATTAAGAAATGAAGAAATTGAATTAGTCTCAAAGTTTCTTTTAAACTCTAAAACAGA
ATGAGATAATGTATTTTACGTTGTCTATAATCATTAAATCACTCCCTGTGTAATTTGTGAGAACCATCTAGTAGCTCGAAATAAAATAAT
GTTGCATCTTTTCTCCCTTGCCATATACTTTGTGATAAATCCTTATCTCATTTTCAGTACTTCATTAAACATTGCAGAAAAAAATATTCC
TTAAGGTCTTAATTGATTTAAAGAAGTAGCTATTCTGAATTGAAATCTCCTTTCATTGAACTGGATGAAAAAATCATGTTTAATAACTGT
TGCTTTTCAATTTTCAAAGCTGTTGAGATATTACATTAAGTATTTCAACTCTTTAATCACTGTTGTTATAATTTGTTTATATTTGATGTT

>In-frame_ENST00000534064_ENST00000281038_TCGA-VQ-A928_INTS4_chr11_77690041_-_NARS2_chr11_78154804_length(amino acids)=246AA_start in transcript=35_stop in transcript=775
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKVAAVDLLVPGVGELFGGGLREER

--------------------------------------------------------------
>In-frame_ENST00000534064_ENST00000528850_TCGA-VQ-A928_INTS4_chr11_77690041_-_NARS2_chr11_78154804_length(transcript)=1223nt_BP=506nt
TAGTGTACGGAAGCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGC
CACAGGAGGAAATTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCC
CAGCAGATGCTTTGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAAC
ATTATTACAAGGAGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACT
GCATTATGGATGATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCA
CTAAGCTACCAGAGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGGTTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTG
GGGAACTCTTTGGAGGAGGCCTCAGAGAAGAACGATACCATTTCTTAGAGGAGCGCTTAGCCAGATCGGGACTTACAGAAGTCTACCAAT
GGTATCTGGACCTTCGTCGATTTGGATCTGTGCCACATGGAGGTTTTGGGATGGGATTTGAACGCTACCTGCAGTGCATCTTGGGTGTTG
ACAATATCAAAGATGTTATCCCTTTCCCAAGGTTTCCTCATTCATGCCTTTTATAGCTGGAAGATTGGTTAAGGAAAAGCACCCCCCATG
GCAGAGACACTGCACATGATTGTGCATACAGCAGAATGCATGTTTGGATTTTAGAAATGCAGATTTCAATATGTAATTGTTGTGCCATAA
GATATCATAGAAAAAATATAAGTGGTTGTGATTTTCTTAGAAAGTTGAGGGTATTTCACGTAAGGATGAGCTCCCGCAAGAAGAGGTACT
TATAGCAAGGGGACTCTCAAATCCATTACCTCAATTAAGAAATGAAGAAATTGAATTAGTCTCAAAGTTTCTTTTAAACTCTAAAACAGA
ATGAGATAATGTATTTTACGTTGTCTATAATCATTAAATCACTCCCTGTGTAATTTGTGAGAACCATCTAGTAGCTCGAAATAAAATAAT

>In-frame_ENST00000534064_ENST00000528850_TCGA-VQ-A928_INTS4_chr11_77690041_-_NARS2_chr11_78154804_length(amino acids)=246AA_start in transcript=35_stop in transcript=775
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKVAAVDLLVPGVGELFGGGLREER

--------------------------------------------------------------
>In-frame_ENST00000529807_ENST00000281038_TCGA-VQ-A928_INTS4_chr11_77690041_-_NARS2_chr11_78154804_length(transcript)=1473nt_BP=494nt
GCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGCCACAGGAGGAAA
TTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCCCAGCAGATGCTT
TGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAACATTATTACAAGG
AGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACTGCATTATGGATG
ATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCACTAAGCTACCAG
AGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGGTTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTGGGGAACTCTTTG
GAGGAGGCCTCAGAGAAGAACGATACCATTTCTTAGAGGAGCGCTTAGCCAGATCGGGACTTACAGAAGTCTACCAATGGTATCTGGACC
TTCGTCGATTTGGATCTGTGCCACATGGAGGTTTTGGGATGGGATTTGAACGCTACCTGCAGTGCATCTTGGGTGTTGACAATATCAAAG
ATGTTATCCCTTTCCCAAGGTTTCCTCATTCATGCCTTTTATAGCTGGAAGATTGGTTAAGGAAAAGCACCCCCCATGGCAGAGACACTG
CACATGATTGTGCATACAGCAGAATGCATGTTTGGATTTTAGAAATGCAGATTTCAATATGTAATTGTTGTGCCATAAGATATCATAGAA
AAAATATAAGTGGTTGTGATTTTCTTAGAAAGTTGAGGGTATTTCACGTAAGGATGAGCTCCCGCAAGAAGAGGTACTTATAGCAAGGGG
ACTCTCAAATCCATTACCTCAATTAAGAAATGAAGAAATTGAATTAGTCTCAAAGTTTCTTTTAAACTCTAAAACAGAATGAGATAATGT
ATTTTACGTTGTCTATAATCATTAAATCACTCCCTGTGTAATTTGTGAGAACCATCTAGTAGCTCGAAATAAAATAATGTTGCATCTTTT
CTCCCTTGCCATATACTTTGTGATAAATCCTTATCTCATTTTCAGTACTTCATTAAACATTGCAGAAAAAAATATTCCTTAAGGTCTTAA
TTGATTTAAAGAAGTAGCTATTCTGAATTGAAATCTCCTTTCATTGAACTGGATGAAAAAATCATGTTTAATAACTGTTGCTTTTCAATT
TTCAAAGCTGTTGAGATATTACATTAAGTATTTCAACTCTTTAATCACTGTTGTTATAATTTGTTTATATTTGATGTTTATAATTTGTCT

>In-frame_ENST00000529807_ENST00000281038_TCGA-VQ-A928_INTS4_chr11_77690041_-_NARS2_chr11_78154804_length(amino acids)=246AA_start in transcript=23_stop in transcript=763
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKVAAVDLLVPGVGELFGGGLREER

--------------------------------------------------------------
>In-frame_ENST00000529807_ENST00000528850_TCGA-VQ-A928_INTS4_chr11_77690041_-_NARS2_chr11_78154804_length(transcript)=1211nt_BP=494nt
GCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGCCACAGGAGGAAA
TTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCCCAGCAGATGCTT
TGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAACATTATTACAAGG
AGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACTGCATTATGGATG
ATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCACTAAGCTACCAG
AGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGGTTGCTGCTGTTGATCTTCTGGTTCCTGGAGTTGGGGAACTCTTTG
GAGGAGGCCTCAGAGAAGAACGATACCATTTCTTAGAGGAGCGCTTAGCCAGATCGGGACTTACAGAAGTCTACCAATGGTATCTGGACC
TTCGTCGATTTGGATCTGTGCCACATGGAGGTTTTGGGATGGGATTTGAACGCTACCTGCAGTGCATCTTGGGTGTTGACAATATCAAAG
ATGTTATCCCTTTCCCAAGGTTTCCTCATTCATGCCTTTTATAGCTGGAAGATTGGTTAAGGAAAAGCACCCCCCATGGCAGAGACACTG
CACATGATTGTGCATACAGCAGAATGCATGTTTGGATTTTAGAAATGCAGATTTCAATATGTAATTGTTGTGCCATAAGATATCATAGAA
AAAATATAAGTGGTTGTGATTTTCTTAGAAAGTTGAGGGTATTTCACGTAAGGATGAGCTCCCGCAAGAAGAGGTACTTATAGCAAGGGG
ACTCTCAAATCCATTACCTCAATTAAGAAATGAAGAAATTGAATTAGTCTCAAAGTTTCTTTTAAACTCTAAAACAGAATGAGATAATGT
ATTTTACGTTGTCTATAATCATTAAATCACTCCCTGTGTAATTTGTGAGAACCATCTAGTAGCTCGAAATAAAATAATGTTGCATCTTTT

>In-frame_ENST00000529807_ENST00000528850_TCGA-VQ-A928_INTS4_chr11_77690041_-_NARS2_chr11_78154804_length(amino acids)=246AA_start in transcript=23_stop in transcript=763
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKVAAVDLLVPGVGELFGGGLREER

--------------------------------------------------------------

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Fusion Gene PPI Analysis for INTS4-NARS2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for INTS4-NARS2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneNARS2Q96I59DB00174AsparagineSmall moleculeApproved|Investigational|Nutraceutical

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Related Diseases for INTS4-NARS2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneINTS4C0033578Prostatic Neoplasms1CTD_human
HgeneINTS4C0376358Malignant neoplasm of prostate1CTD_human
TgeneNARS2C4015643COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 243CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneNARS2C0023264Leigh Disease2CLINGEN
TgeneNARS2C1838951LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY2CLINGEN
TgeneNARS2C1850597Leigh Syndrome Due To Mitochondrial Complex II Deficiency2CLINGEN
TgeneNARS2C1850598Leigh Syndrome due to Mitochondrial Complex III Deficiency2CLINGEN
TgeneNARS2C1850599Leigh Syndrome due to Mitochondrial Complex IV Deficiency2CLINGEN
TgeneNARS2C1850600Leigh Syndrome due to Mitochondrial Complex V Deficiency2CLINGEN
TgeneNARS2C2931891Necrotizing encephalopathy, infantile subacute, of Leigh2CLINGEN
TgeneNARS2C0036572Seizures1GENOMICS_ENGLAND
TgeneNARS2C3711374Nonsyndromic Deafness1CLINGEN