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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ITGB4-SLC16A5 (FusionGDB2 ID:40375)

Fusion Gene Summary for ITGB4-SLC16A5

check button Fusion gene summary
Fusion gene informationFusion gene name: ITGB4-SLC16A5
Fusion gene ID: 40375
HgeneTgene
Gene symbol

ITGB4

SLC16A5

Gene ID

3691

9121

Gene nameintegrin subunit beta 4solute carrier family 16 member 5
SynonymsCD104|GP150MCT5|MCT6
Cytomap

17q25.1

17q25.1

Type of geneprotein-codingprotein-coding
Descriptionintegrin beta-4CD104 antigenmonocarboxylate transporter 6monocarboxylate transporter 5solute carrier family 16 (monocarboxylate transporter), member 5solute carrier family 16 (monocarboxylic acid transporters), member 5solute carrier family 16, member 5 (monocarboxylic acid tran
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000579662, ENST00000339591, 
ENST00000200181, ENST00000450894, 
ENST00000449880, ENST00000584558, 
ENST00000580123, ENST00000585293, 
ENST00000329783, ENST00000450736, 
ENST00000538213, 
Fusion gene scores* DoF score23 X 19 X 10=43707 X 6 X 5=210
# samples 298
** MAII scorelog2(29/4370*10)=-3.91350847437303
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/210*10)=-1.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ITGB4 [Title/Abstract] AND SLC16A5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointITGB4(73747192)-SLC16A5(73094133), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneITGB4

GO:0009611

response to wounding

19403692

HgeneITGB4

GO:0031581

hemidesmosome assembly

12482924


check buttonFusion gene breakpoints across ITGB4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across SLC16A5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-C8-A26X-01AITGB4chr17

73747192

+SLC16A5chr17

73094133

+
ChimerDB4BRCATCGA-C8-A26X-01AITGB4chr17

73747192

+SLC16A5chr17

73094133

+
ChimerDB4BRCATCGA-C8-A26X-01AITGB4chr17

73747192

-SLC16A5chr17

73094133

+


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Fusion Gene ORF analysis for ITGB4-SLC16A5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000579662ENST00000580123ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000579662ENST00000585293ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000579662ENST00000329783ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000579662ENST00000450736ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000579662ENST00000538213ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
In-frameENST00000339591ENST00000580123ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000339591ENST00000585293ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000339591ENST00000329783ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000339591ENST00000450736ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000339591ENST00000538213ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
In-frameENST00000200181ENST00000580123ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000200181ENST00000585293ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000200181ENST00000329783ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000200181ENST00000450736ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000200181ENST00000538213ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
In-frameENST00000450894ENST00000580123ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000450894ENST00000585293ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000450894ENST00000329783ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000450894ENST00000450736ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000450894ENST00000538213ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
In-frameENST00000449880ENST00000580123ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000449880ENST00000585293ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000449880ENST00000329783ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000449880ENST00000450736ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
5CDS-3UTRENST00000449880ENST00000538213ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
intron-3CDSENST00000584558ENST00000580123ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
intron-3UTRENST00000584558ENST00000585293ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
intron-3UTRENST00000584558ENST00000329783ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
intron-3UTRENST00000584558ENST00000450736ITGB4chr17

73747192

+SLC16A5chr17

73094133

+
intron-3UTRENST00000584558ENST00000538213ITGB4chr17

73747192

+SLC16A5chr17

73094133

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000579662ITGB4chr1773747192+ENST00000580123SLC16A5chr1773094133+5487403924653571703
ENST00000339591ITGB4chr1773747192+ENST00000580123SLC16A5chr1773094133+5428398016352981711
ENST00000200181ITGB4chr1773747192+ENST00000580123SLC16A5chr1773094133+5428398016352981711
ENST00000450894ITGB4chr1773747192+ENST00000580123SLC16A5chr1773094133+5367391910252371711
ENST00000449880ITGB4chr1773747192+ENST00000580123SLC16A5chr1773094133+52493801851191703

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000579662ENST00000580123ITGB4chr1773747192+SLC16A5chr1773094133+0.0036704130.9963296
ENST00000339591ENST00000580123ITGB4chr1773747192+SLC16A5chr1773094133+0.0036566040.99634343
ENST00000200181ENST00000580123ITGB4chr1773747192+SLC16A5chr1773094133+0.0036566040.99634343
ENST00000450894ENST00000580123ITGB4chr1773747192+SLC16A5chr1773094133+0.0034798720.99652016
ENST00000449880ENST00000580123ITGB4chr1773747192+SLC16A5chr1773094133+0.0030699950.99693006

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Fusion Genomic Features for ITGB4-SLC16A5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ITGB4chr1773747192+SLC16A5chr1773094132+1.25E-050.9999875
ITGB4chr1773747192+SLC16A5chr1773094132+1.25E-050.9999875

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ITGB4-SLC16A5


check button Go to

FGviewer for the breakpoints of chr17:73747192-chr17:73094133

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+30401129_12181264.33333333333331823.0DomainFibronectin type-III 1
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+3040131_3291264.33333333333331823.0DomainNote=VWFA
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+304029_731264.33333333333331823.0DomainNote=PSI
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+3040979_10841264.33333333333331823.0DomainNote=Calx-beta
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+30401129_12181264.33333333333331806.0DomainFibronectin type-III 1
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+3040131_3291264.33333333333331806.0DomainNote=VWFA
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+304029_731264.33333333333331806.0DomainNote=PSI
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+3040979_10841264.33333333333331806.0DomainNote=Calx-beta
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+29391129_12181264.33333333333331806.0DomainFibronectin type-III 1
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+2939131_3291264.33333333333331806.0DomainNote=VWFA
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+293929_731264.33333333333331806.0DomainNote=PSI
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+2939979_10841264.33333333333331806.0DomainNote=Calx-beta
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+30391129_12181264.33333333333331753.0DomainFibronectin type-III 1
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+3039131_3291264.33333333333331753.0DomainNote=VWFA
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+303929_731264.33333333333331753.0DomainNote=PSI
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+3039979_10841264.33333333333331753.0DomainNote=Calx-beta
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+30391129_12181264.33333333333331753.0DomainFibronectin type-III 1
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+3039131_3291264.33333333333331753.0DomainNote=VWFA
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+303929_731264.33333333333331753.0DomainNote=PSI
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+3039979_10841264.33333333333331753.0DomainNote=Calx-beta
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+3040194_1991264.33333333333331823.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+3040456_6191264.33333333333331823.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+3040732_7491264.33333333333331823.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+3040194_1991264.33333333333331806.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+3040456_6191264.33333333333331806.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+3040732_7491264.33333333333331806.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+2939194_1991264.33333333333331806.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+2939456_6191264.33333333333331806.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+2939732_7491264.33333333333331806.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+3039194_1991264.33333333333331753.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+3039456_6191264.33333333333331753.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+3039732_7491264.33333333333331753.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+3039194_1991264.33333333333331753.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+3039456_6191264.33333333333331753.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+3039732_7491264.33333333333331753.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+3040456_5021264.33333333333331823.0RepeatNote=I
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+3040503_5421264.33333333333331823.0RepeatNote=II
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+3040543_5811264.33333333333331823.0RepeatNote=III
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+3040582_6191264.33333333333331823.0RepeatNote=IV
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+3040456_5021264.33333333333331806.0RepeatNote=I
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+3040503_5421264.33333333333331806.0RepeatNote=II
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+3040543_5811264.33333333333331806.0RepeatNote=III
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+3040582_6191264.33333333333331806.0RepeatNote=IV
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+2939456_5021264.33333333333331806.0RepeatNote=I
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+2939503_5421264.33333333333331806.0RepeatNote=II
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+2939543_5811264.33333333333331806.0RepeatNote=III
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+2939582_6191264.33333333333331806.0RepeatNote=IV
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+3039456_5021264.33333333333331753.0RepeatNote=I
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+3039503_5421264.33333333333331753.0RepeatNote=II
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+3039543_5811264.33333333333331753.0RepeatNote=III
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+3039582_6191264.33333333333331753.0RepeatNote=IV
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+3039456_5021264.33333333333331753.0RepeatNote=I
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+3039503_5421264.33333333333331753.0RepeatNote=II
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+3039543_5811264.33333333333331753.0RepeatNote=III
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+3039582_6191264.33333333333331753.0RepeatNote=IV
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+304028_7101264.33333333333331823.0Topological domainExtracellular
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+304028_7101264.33333333333331806.0Topological domainExtracellular
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+293928_7101264.33333333333331806.0Topological domainExtracellular
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+303928_7101264.33333333333331753.0Topological domainExtracellular
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+303928_7101264.33333333333331753.0Topological domainExtracellular
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+3040711_7331264.33333333333331823.0TransmembraneHelical
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+3040711_7331264.33333333333331806.0TransmembraneHelical
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+2939711_7331264.33333333333331806.0TransmembraneHelical
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+3039711_7331264.33333333333331753.0TransmembraneHelical
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+3039711_7331264.33333333333331753.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327102_11066.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327132_13766.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327159_17166.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327193_23966.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327261_27466.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327296_30566.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327327_32966.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327351_36766.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327389_39666.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327418_50566.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST000003297832775_8066.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616102_11066.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616132_13766.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616159_17166.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616193_23966.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616261_27466.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616296_30566.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616327_32966.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616351_36766.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616389_39666.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616418_50566.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST000004507361675_8066.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327102_11066.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327132_13766.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327159_17166.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327193_23966.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327261_27466.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327296_30566.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327327_32966.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327351_36766.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327389_39666.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327418_50566.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST000005801232775_8066.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327111_13166.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327138_15866.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327172_19266.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327240_26066.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327275_29566.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327306_32666.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327330_35066.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327368_38866.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000032978327397_41766.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST000003297832781_10166.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616111_13166.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616138_15866.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616172_19266.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616240_26066.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616275_29566.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616306_32666.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616330_35066.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616368_38866.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000045073616397_41766.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST000004507361681_10166.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327111_13166.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327138_15866.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327172_19266.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327240_26066.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327275_29566.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327306_32666.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327330_35066.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327368_38866.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST0000058012327397_41766.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST000005801232781_10166.33333333333333506.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+30401222_13211264.33333333333331823.0DomainFibronectin type-III 2
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+30401530_16251264.33333333333331823.0DomainFibronectin type-III 3
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+30401643_17391264.33333333333331823.0DomainFibronectin type-III 4
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+30401222_13211264.33333333333331806.0DomainFibronectin type-III 2
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+30401530_16251264.33333333333331806.0DomainFibronectin type-III 3
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+30401643_17391264.33333333333331806.0DomainFibronectin type-III 4
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+29391222_13211264.33333333333331806.0DomainFibronectin type-III 2
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+29391530_16251264.33333333333331806.0DomainFibronectin type-III 3
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+29391643_17391264.33333333333331806.0DomainFibronectin type-III 4
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+30391222_13211264.33333333333331753.0DomainFibronectin type-III 2
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+30391530_16251264.33333333333331753.0DomainFibronectin type-III 3
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+30391643_17391264.33333333333331753.0DomainFibronectin type-III 4
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+30391222_13211264.33333333333331753.0DomainFibronectin type-III 2
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+30391530_16251264.33333333333331753.0DomainFibronectin type-III 3
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+30391643_17391264.33333333333331753.0DomainFibronectin type-III 4
HgeneITGB4chr17:73747192chr17:73094133ENST00000200181+3040734_18221264.33333333333331823.0Topological domainCytoplasmic
HgeneITGB4chr17:73747192chr17:73094133ENST00000339591+3040734_18221264.33333333333331806.0Topological domainCytoplasmic
HgeneITGB4chr17:73747192chr17:73094133ENST00000449880+2939734_18221264.33333333333331806.0Topological domainCytoplasmic
HgeneITGB4chr17:73747192chr17:73094133ENST00000450894+3039734_18221264.33333333333331753.0Topological domainCytoplasmic
HgeneITGB4chr17:73747192chr17:73094133ENST00000579662+3039734_18221264.33333333333331753.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST00000329783271_1766.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST000003297832739_5366.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST00000450736161_1766.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST000004507361639_5366.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST00000580123271_1766.33333333333333506.0Topological domainCytoplasmic
TgeneSLC16A5chr17:73747192chr17:73094133ENST000005801232739_5366.33333333333333506.0Topological domainExtracellular
TgeneSLC16A5chr17:73747192chr17:73094133ENST000003297832718_3866.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST000003297832754_7466.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST000004507361618_3866.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST000004507361654_7466.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST000005801232718_3866.33333333333333506.0TransmembraneHelical
TgeneSLC16A5chr17:73747192chr17:73094133ENST000005801232754_7466.33333333333333506.0TransmembraneHelical


Top

Fusion Gene Sequence for ITGB4-SLC16A5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000579662_ENST00000580123_TCGA-C8-A26X-01A_ITGB4_chr17_73747192_+_SLC16A5_chr17_73094133_length(transcript)=5487nt_BP=4039nt
CCGGCGGCGGCACCCAGCTCCTGCCCCGACAGGTGCGCGCCGCGCGAAGGAATGCAGCCGGTCTGACTCACCAGCGCCTCCTTCCTACCT
GCGCGCCCGCCCCATAAAGCGCTGCCCGCCTCGTCCCCACCCCCCCAACCCCCGCGCCCGCCCTCGGACAGTCCCTGCTCGCCCGCGCGC
TGCAGCCCCATCTCCTAGCGGCAGCCCAGGCGCGGAGGGAGCGAGTCCGCCCCGAGGAGGAAGAGGATGGCAGGGCCACGCCCCAGCCCA
TGGGCCAGGCTGCTCCTGGCAGCCTTGATCAGCGTCAGCCTCTCTGGGACCTTGGCAAACCGCTGCAAGAAGGCCCCAGTGAAGAGCTGC
ACGGAGTGTGTCCGTGTGGATAAGGACTGCGCCTACTGCACAGACGAGATGTTCAGGGACCGGCGCTGCAACACCCAGGCGGAGCTGCTG
GCCGCGGGCTGCCAGCGGGAGAGCATCGTGGTCATGGAGAGCAGCTTCCAAATCACAGAGGAGACCCAGATTGACACCACCCTGCGGCGC
AGCCAGATGTCCCCCCAAGGCCTGCGGGTCCGTCTGCGGCCCGGTGAGGAGCGGCATTTTGAGCTGGAGGTGTTTGAGCCACTGGAGAGC
CCCGTGGACCTGTACATCCTCATGGACTTCTCCAACTCCATGTCCGATGATCTGGACAACCTCAAGAAGATGGGGCAGAACCTGGCTCGG
GTCCTGAGCCAGCTCACCAGCGACTACACTATTGGATTTGGCAAGTTTGTGGACAAAGTCAGCGTCCCGCAGACGGACATGAGGCCTGAG
AAGCTGAAGGAGCCCTGGCCCAACAGTGACCCCCCCTTCTCCTTCAAGAACGTCATCAGCCTGACAGAAGATGTGGATGAGTTCCGGAAT
AAACTGCAGGGAGAGCGGATCTCAGGCAACCTGGATGCTCCTGAGGGCGGCTTCGATGCCATCCTGCAGACAGCTGTGTGCACGAGGGAC
ATTGGCTGGCGCCCGGACAGCACCCACCTGCTGGTCTTCTCCACCGAGTCAGCCTTCCACTATGAGGCTGATGGCGCCAACGTGCTGGCT
GGCATCATGAGCCGCAACGATGAACGGTGCCACCTGGACACCACGGGCACCTACACCCAGTACAGGACACAGGACTACCCGTCGGTGCCC
ACCCTGGTGCGCCTGCTCGCCAAGCACAACATCATCCCCATCTTTGCTGTCACCAACTACTCCTATAGCTACTACGAGAAGCTTCACACC
TATTTCCCTGTCTCCTCACTGGGGGTGCTGCAGGAGGACTCGTCCAACATCGTGGAGCTGCTGGAGGAGGCCTTCAATCGGATCCGCTCC
AACCTGGACATCCGGGCCCTAGACAGCCCCCGAGGCCTTCGGACAGAGGTCACCTCCAAGATGTTCCAGAAGACGAGGACTGGGTCCTTT
CACATCCGGCGGGGGGAAGTGGGTATATACCAGGTGCAGCTGCGGGCCCTTGAGCACGTGGATGGGACGCACGTGTGCCAGCTGCCGGAG
GACCAGAAGGGCAACATCCATCTGAAACCTTCCTTCTCCGACGGCCTCAAGATGGACGCGGGCATCATCTGTGATGTGTGCACCTGCGAG
CTGCAAAAAGAGGTGCGGTCAGCTCGCTGCAGCTTCAACGGAGACTTCGTGTGCGGACAGTGTGTGTGCAGCGAGGGCTGGAGTGGCCAG
ACCTGCAACTGCTCCACCGGCTCTCTGAGTGACATTCAGCCCTGCCTGCGGGAGGGCGAGGACAAGCCGTGCTCCGGCCGTGGGGAGTGC
CAGTGCGGGCACTGTGTGTGCTACGGCGAAGGCCGCTACGAGGGTCAGTTCTGCGAGTATGACAACTTCCAGTGTCCCCGCACTTCCGGG
TTCCTCTGCAATGACCGAGGACGCTGCTCCATGGGCCAGTGTGTGTGTGAGCCTGGTTGGACAGGCCCAAGCTGTGACTGTCCCCTCAGC
AATGCCACCTGCATCGACAGCAATGGGGGCATCTGTAATGGACGTGGCCACTGTGAGTGTGGCCGCTGCCACTGCCACCAGCAGTCGCTC
TACACGGACACCATCTGCGAGATCAACTACTCGGCGATCCACCCGGGCCTCTGCGAGGACCTACGCTCCTGCGTGCAGTGCCAGGCGTGG
GGCACCGGCGAGAAGAAGGGGCGCACGTGTGAGGAATGCAACTTCAAGGTCAAGATGGTGGACGAGCTTAAGAGAGCCGAGGAGGTGGTG
GTGCGCTGCTCCTTCCGGGACGAGGATGACGACTGCACCTACAGCTACACCATGGAAGGTGACGGCGCCCCTGGGCCCAACAGCACTGTC
CTGGTGCACAAGAAGAAGGACTGCCCTCCGGGCTCCTTCTGGTGGCTCATCCCCCTGCTCCTCCTCCTCCTGCCGCTCCTGGCCCTGCTA
CTGCTGCTATGCTGGAAGTACTGTGCCTGCTGCAAGGCCTGCCTGGCACTTCTCCCGTGCTGCAACCGAGGTCACATGGTGGGCTTTAAG
GAAGACCACTACATGCTGCGGGAGAACCTGATGGCCTCTGACCACTTGGACACGCCCATGCTGCGCAGCGGGAACCTCAAGGGCCGTGAC
GTGGTCCGCTGGAAGGTCACCAACAACATGCAGCGGCCTGGCTTTGCCACTCATGCCGCCAGCATCAACCCCACAGAGCTGGTGCCCTAC
GGGCTGTCCTTGCGCCTGGCCCGCCTTTGCACCGAGAACCTGCTGAAGCCTGACACTCGGGAGTGCGCCCAGCTGCGCCAGGAGGTGGAG
GAGAACCTGAACGAGGTCTACAGGCAGATCTCCGGTGTACACAAGCTCCAGCAGACCAAGTTCCGGCAGCAGCCCAATGCCGGGAAAAAG
CAAGACCACACCATTGTGGACACAGTGCTGATGGCGCCCCGCTCGGCCAAGCCGGCCCTGCTGAAGCTTACAGAGAAGCAGGTGGAACAG
AGGGCCTTCCACGACCTCAAGGTGGCCCCCGGCTACTACACCCTCACTGCAGACCAGGACGCCCGGGGCATGGTGGAGTTCCAGGAGGGC
GTGGAGCTGGTGGACGTACGGGTGCCCCTCTTTATCCGGCCTGAGGATGACGACGAGAAGCAGCTGCTGGTGGAGGCCATCGACGTGCCC
GCAGGCACTGCCACCCTCGGCCGCCGCCTGGTAAACATCACCATCATCAAGGAGCAAGCCAGAGACGTGGTGTCCTTTGAGCAGCCTGAG
TTCTCGGTCAGCCGCGGGGACCAGGTGGCCCGCATCCCTGTCATCCGGCGTGTCCTGGACGGCGGGAAGTCCCAGGTCTCCTACCGCACA
CAGGATGGCACCGCGCAGGGCAACCGGGACTACATCCCCGTGGAGGGTGAGCTGCTGTTCCAGCCTGGGGAGGCCTGGAAAGAGCTGCAG
GTGAAGCTCCTGGAGCTGCAAGAAGTTGACTCCCTCCTGCGGGGCCGCCAGGTCCGCCGTTTCCACGTCCAGCTCAGCAACCCTAAGTTT
GGGGCCCACCTGGGCCAGCCCCACTCCACCACCATCATCATCAGGGACCCAGATGAACTGGACCGGAGCTTCACGAGTCAGATGTTGTCA
TCACAGCCACCCCCTCACGGCGACCTGGGCGCCCCGCAGAACCCCAATGCTAAGGCCGCTGGGTCCAGGAAGATCCATTTCAACTGGCTG
CCCCCTTCTGGCAAGCCAATGGGGTACAGGGTAAAGTACTGGATTCAGGGTGACTCCGAATCCGAAGCCCACCTGCTCGACAGCAAGGTG
CCCTCAGTGGAGCTCACCAACCTGTACCCGTATTGCGACTATGAGATGAAGGTGTGCGCCTACGGGGCTCAGGGCGAGGGACCCTACAGC
TCCCTGGTGTCCTGCCGCACCCACCAGGAAGTGCCCAGCGAGCCAGGGCGTCTGGCCTTCAATGTCGTCTCCTCCACGGTGACCCAGCTG
AGCTGGGCTGAGCCGGCTGAGACCAACGGTGAGATCACAGCCTACGAGGTCTGCTATGGCCTGGTCAACGATGACAACCGGCCCCTGTGC
AGCATCCTGGTGGGACGCTTCGGCTGCCGAGTGACCGTGATGCTGGGGGGCGTGCTGGCCAGCCTGGGCATGGTGGCCAGCTCCTTCTCT
CACAACCTCAGCCAGCTCTACTTCACAGCAGGATTCATCACAGGCCTGGGCATGTGCTTCAGCTTCCAGTCAAGCATCACGGTGCTGGGC
TTCTACTTTGTCCGCCGGCGGGTGCTGGCCAACGCGCTGGCCTCGATGGGCGTCTCCCTGGGCATCACCCTCTGGCCGCTGCTCTCCCGC
TACCTTCTGGAGAACCTGGGCTGGAGGGGTACCTTCCTTGTCTTCGGCGGGATCTTTCTCCACTGCTGCATCTGCGGGGCCATCATAAGG
CCTGTGGCCACCAGTGTGGCCCCTGAGACCAAAGAATGTCCCCCGCCACCTCCCGAGACACCTGCACTTGGCTGCCTGGCTGCATGCGGC
CGGACCATCCAGCGCCACCTGGCCTTCGACATCCTGCGGCACAACACAGGCTACTGCGTGTACATACTGGGTGTGATGTGGTCCGTCCTG
GGCTTCCCACTGCCACAAGTCTTCCTGGTGCCATATGCCATGTGGCACAGCGTGGACGAGCAGCAGGCAGCCCTCCTCATCTCCATCATC
GGCTTCAGCAACATCTTCCTGAGGCCCCTAGCCGGGCTGATGGCAGGACGGCCGGCCTTTGCTAGCCACCGCAAGTACCTGTTCAGCCTG
GCACTCCTGCTCAATGGGCTCACTAACCTGGTGTGTGCGGCATCAGGTGACTTCTGGGTGCTCGTGGGCTACTGCCTGGCGTACAGCGTG
TCCATGAGTGGCATCGGCGCCCTCATCTTCCAGGTTCTCATGGACATCGTCCCCATGGATCAGTTCCCCAGAGCCCTGGGACTCTTCACT
GTCCTGGACGGCCTTGCTTTCCTCATCTCCCCACCACTGGCCGGGTTGCTCCTGGACGCCACCAACAACTTTAGCTATGTTTTCTACATG
TCCAGCTTCTTCCTCATCTCAGCTGCCCTCTTCATGGGTGGCAGCTTCTACGCCCTGCAGAAGAAGGAGCAAGGCAAGCAGGCTGTCGCG
GCGGATGCCCTGGAGCGGGATCTTTTCTTGGAAGCCAAAGACGGTCCTGGGAAGCAACGGTCCCCTGAGATCATGTGCCAGTCTTCCCGC
CAGCCACGTCCAGCTGGCGTCAATAAGCATCTTTGGGGATGTCCTGCCTCCTCCAGGACCAGCCATGAGTGGCTCTTATGGCCAAAGGCG
GTACTGCAGGCCAAGCAAACGGCTCTGGGCTGGAATAGCCCTACCTGAGTGCCCTGTTTGACTCCGCCACTATCTGCCATGTGAGTTGGG

>In-frame_ENST00000579662_ENST00000580123_TCGA-C8-A26X-01A_ITGB4_chr17_73747192_+_SLC16A5_chr17_73094133_length(amino acids)=1703AA_start in transcript=246_stop in transcript=5357
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITEET
QIDTTLRRSQMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYE
ADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSDGLKMDAGI
ICDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLR
SCVQCQAWGTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLRSGNLKGRDVVRWKVTNNMQRPGFATHAASI
NPTELVPYGLSLRLARLCTENLLKPDTRECAQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPAGTATLGRRLVNITIIKEQARD
VVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESE
AHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
NDDNRPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGI
TLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYI
LGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLV
GYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQKK

--------------------------------------------------------------
>In-frame_ENST00000339591_ENST00000580123_TCGA-C8-A26X-01A_ITGB4_chr17_73747192_+_SLC16A5_chr17_73094133_length(transcript)=5428nt_BP=3980nt
GCGCTGCCCGCCTCGTCCCCACCCCCCCAACCCCCGCGCCCGCCCTCGGACAGTCCCTGCTCGCCCGCGCGCTGCAGCCCCATCTCCTAG
CGGCAGCCCAGGCGCGGAGGGAGCGAGTCCGCCCCGAGGTAGGTCCAGGACGGGCGCACAGCAGCAGCCGAGGCTGGCCGGGAGAGGGAG
GAAGAGGATGGCAGGGCCACGCCCCAGCCCATGGGCCAGGCTGCTCCTGGCAGCCTTGATCAGCGTCAGCCTCTCTGGGACCTTGGCAAA
CCGCTGCAAGAAGGCCCCAGTGAAGAGCTGCACGGAGTGTGTCCGTGTGGATAAGGACTGCGCCTACTGCACAGACGAGATGTTCAGGGA
CCGGCGCTGCAACACCCAGGCGGAGCTGCTGGCCGCGGGCTGCCAGCGGGAGAGCATCGTGGTCATGGAGAGCAGCTTCCAAATCACAGA
GGAGACCCAGATTGACACCACCCTGCGGCGCAGCCAGATGTCCCCCCAAGGCCTGCGGGTCCGTCTGCGGCCCGGTGAGGAGCGGCATTT
TGAGCTGGAGGTGTTTGAGCCACTGGAGAGCCCCGTGGACCTGTACATCCTCATGGACTTCTCCAACTCCATGTCCGATGATCTGGACAA
CCTCAAGAAGATGGGGCAGAACCTGGCTCGGGTCCTGAGCCAGCTCACCAGCGACTACACTATTGGATTTGGCAAGTTTGTGGACAAAGT
CAGCGTCCCGCAGACGGACATGAGGCCTGAGAAGCTGAAGGAGCCCTGGCCCAACAGTGACCCCCCCTTCTCCTTCAAGAACGTCATCAG
CCTGACAGAAGATGTGGATGAGTTCCGGAATAAACTGCAGGGAGAGCGGATCTCAGGCAACCTGGATGCTCCTGAGGGCGGCTTCGATGC
CATCCTGCAGACAGCTGTGTGCACGAGGGACATTGGCTGGCGCCCGGACAGCACCCACCTGCTGGTCTTCTCCACCGAGTCAGCCTTCCA
CTATGAGGCTGATGGCGCCAACGTGCTGGCTGGCATCATGAGCCGCAACGATGAACGGTGCCACCTGGACACCACGGGCACCTACACCCA
GTACAGGACACAGGACTACCCGTCGGTGCCCACCCTGGTGCGCCTGCTCGCCAAGCACAACATCATCCCCATCTTTGCTGTCACCAACTA
CTCCTATAGCTACTACGAGAAGCTTCACACCTATTTCCCTGTCTCCTCACTGGGGGTGCTGCAGGAGGACTCGTCCAACATCGTGGAGCT
GCTGGAGGAGGCCTTCAATCGGATCCGCTCCAACCTGGACATCCGGGCCCTAGACAGCCCCCGAGGCCTTCGGACAGAGGTCACCTCCAA
GATGTTCCAGAAGACGAGGACTGGGTCCTTTCACATCCGGCGGGGGGAAGTGGGTATATACCAGGTGCAGCTGCGGGCCCTTGAGCACGT
GGATGGGACGCACGTGTGCCAGCTGCCGGAGGACCAGAAGGGCAACATCCATCTGAAACCTTCCTTCTCCGACGGCCTCAAGATGGACGC
GGGCATCATCTGTGATGTGTGCACCTGCGAGCTGCAAAAAGAGGTGCGGTCAGCTCGCTGCAGCTTCAACGGAGACTTCGTGTGCGGACA
GTGTGTGTGCAGCGAGGGCTGGAGTGGCCAGACCTGCAACTGCTCCACCGGCTCTCTGAGTGACATTCAGCCCTGCCTGCGGGAGGGCGA
GGACAAGCCGTGCTCCGGCCGTGGGGAGTGCCAGTGCGGGCACTGTGTGTGCTACGGCGAAGGCCGCTACGAGGGTCAGTTCTGCGAGTA
TGACAACTTCCAGTGTCCCCGCACTTCCGGGTTCCTCTGCAATGACCGAGGACGCTGCTCCATGGGCCAGTGTGTGTGTGAGCCTGGTTG
GACAGGCCCAAGCTGTGACTGTCCCCTCAGCAATGCCACCTGCATCGACAGCAATGGGGGCATCTGTAATGGACGTGGCCACTGTGAGTG
TGGCCGCTGCCACTGCCACCAGCAGTCGCTCTACACGGACACCATCTGCGAGATCAACTACTCGGCGATCCACCCGGGCCTCTGCGAGGA
CCTACGCTCCTGCGTGCAGTGCCAGGCGTGGGGCACCGGCGAGAAGAAGGGGCGCACGTGTGAGGAATGCAACTTCAAGGTCAAGATGGT
GGACGAGCTTAAGAGAGCCGAGGAGGTGGTGGTGCGCTGCTCCTTCCGGGACGAGGATGACGACTGCACCTACAGCTACACCATGGAAGG
TGACGGCGCCCCTGGGCCCAACAGCACTGTCCTGGTGCACAAGAAGAAGGACTGCCCTCCGGGCTCCTTCTGGTGGCTCATCCCCCTGCT
CCTCCTCCTCCTGCCGCTCCTGGCCCTGCTACTGCTGCTATGCTGGAAGTACTGTGCCTGCTGCAAGGCCTGCCTGGCACTTCTCCCGTG
CTGCAACCGAGGTCACATGGTGGGCTTTAAGGAAGACCACTACATGCTGCGGGAGAACCTGATGGCCTCTGACCACTTGGACACGCCCAT
GCTGCGCAGCGGGAACCTCAAGGGCCGTGACGTGGTCCGCTGGAAGGTCACCAACAACATGCAGCGGCCTGGCTTTGCCACTCATGCCGC
CAGCATCAACCCCACAGAGCTGGTGCCCTACGGGCTGTCCTTGCGCCTGGCCCGCCTTTGCACCGAGAACCTGCTGAAGCCTGACACTCG
GGAGTGCGCCCAGCTGCGCCAGGAGGTGGAGGAGAACCTGAACGAGGTCTACAGGCAGATCTCCGGTGTACACAAGCTCCAGCAGACCAA
GTTCCGGCAGCAGCCCAATGCCGGGAAAAAGCAAGACCACACCATTGTGGACACAGTGCTGATGGCGCCCCGCTCGGCCAAGCCGGCCCT
GCTGAAGCTTACAGAGAAGCAGGTGGAACAGAGGGCCTTCCACGACCTCAAGGTGGCCCCCGGCTACTACACCCTCACTGCAGACCAGGA
CGCCCGGGGCATGGTGGAGTTCCAGGAGGGCGTGGAGCTGGTGGACGTACGGGTGCCCCTCTTTATCCGGCCTGAGGATGACGACGAGAA
GCAGCTGCTGGTGGAGGCCATCGACGTGCCCGCAGGCACTGCCACCCTCGGCCGCCGCCTGGTAAACATCACCATCATCAAGGAGCAAGC
CAGAGACGTGGTGTCCTTTGAGCAGCCTGAGTTCTCGGTCAGCCGCGGGGACCAGGTGGCCCGCATCCCTGTCATCCGGCGTGTCCTGGA
CGGCGGGAAGTCCCAGGTCTCCTACCGCACACAGGATGGCACCGCGCAGGGCAACCGGGACTACATCCCCGTGGAGGGTGAGCTGCTGTT
CCAGCCTGGGGAGGCCTGGAAAGAGCTGCAGGTGAAGCTCCTGGAGCTGCAAGAAGTTGACTCCCTCCTGCGGGGCCGCCAGGTCCGCCG
TTTCCACGTCCAGCTCAGCAACCCTAAGTTTGGGGCCCACCTGGGCCAGCCCCACTCCACCACCATCATCATCAGGGACCCAGATGAACT
GGACCGGAGCTTCACGAGTCAGATGTTGTCATCACAGCCACCCCCTCACGGCGACCTGGGCGCCCCGCAGAACCCCAATGCTAAGGCCGC
TGGGTCCAGGAAGATCCATTTCAACTGGCTGCCCCCTTCTGGCAAGCCAATGGGGTACAGGGTAAAGTACTGGATTCAGGGTGACTCCGA
ATCCGAAGCCCACCTGCTCGACAGCAAGGTGCCCTCAGTGGAGCTCACCAACCTGTACCCGTATTGCGACTATGAGATGAAGGTGTGCGC
CTACGGGGCTCAGGGCGAGGGACCCTACAGCTCCCTGGTGTCCTGCCGCACCCACCAGGAAGTGCCCAGCGAGCCAGGGCGTCTGGCCTT
CAATGTCGTCTCCTCCACGGTGACCCAGCTGAGCTGGGCTGAGCCGGCTGAGACCAACGGTGAGATCACAGCCTACGAGGTCTGCTATGG
CCTGGTCAACGATGACAACCGGCCCCTGTGCAGCATCCTGGTGGGACGCTTCGGCTGCCGAGTGACCGTGATGCTGGGGGGCGTGCTGGC
CAGCCTGGGCATGGTGGCCAGCTCCTTCTCTCACAACCTCAGCCAGCTCTACTTCACAGCAGGATTCATCACAGGCCTGGGCATGTGCTT
CAGCTTCCAGTCAAGCATCACGGTGCTGGGCTTCTACTTTGTCCGCCGGCGGGTGCTGGCCAACGCGCTGGCCTCGATGGGCGTCTCCCT
GGGCATCACCCTCTGGCCGCTGCTCTCCCGCTACCTTCTGGAGAACCTGGGCTGGAGGGGTACCTTCCTTGTCTTCGGCGGGATCTTTCT
CCACTGCTGCATCTGCGGGGCCATCATAAGGCCTGTGGCCACCAGTGTGGCCCCTGAGACCAAAGAATGTCCCCCGCCACCTCCCGAGAC
ACCTGCACTTGGCTGCCTGGCTGCATGCGGCCGGACCATCCAGCGCCACCTGGCCTTCGACATCCTGCGGCACAACACAGGCTACTGCGT
GTACATACTGGGTGTGATGTGGTCCGTCCTGGGCTTCCCACTGCCACAAGTCTTCCTGGTGCCATATGCCATGTGGCACAGCGTGGACGA
GCAGCAGGCAGCCCTCCTCATCTCCATCATCGGCTTCAGCAACATCTTCCTGAGGCCCCTAGCCGGGCTGATGGCAGGACGGCCGGCCTT
TGCTAGCCACCGCAAGTACCTGTTCAGCCTGGCACTCCTGCTCAATGGGCTCACTAACCTGGTGTGTGCGGCATCAGGTGACTTCTGGGT
GCTCGTGGGCTACTGCCTGGCGTACAGCGTGTCCATGAGTGGCATCGGCGCCCTCATCTTCCAGGTTCTCATGGACATCGTCCCCATGGA
TCAGTTCCCCAGAGCCCTGGGACTCTTCACTGTCCTGGACGGCCTTGCTTTCCTCATCTCCCCACCACTGGCCGGGTTGCTCCTGGACGC
CACCAACAACTTTAGCTATGTTTTCTACATGTCCAGCTTCTTCCTCATCTCAGCTGCCCTCTTCATGGGTGGCAGCTTCTACGCCCTGCA
GAAGAAGGAGCAAGGCAAGCAGGCTGTCGCGGCGGATGCCCTGGAGCGGGATCTTTTCTTGGAAGCCAAAGACGGTCCTGGGAAGCAACG
GTCCCCTGAGATCATGTGCCAGTCTTCCCGCCAGCCACGTCCAGCTGGCGTCAATAAGCATCTTTGGGGATGTCCTGCCTCCTCCAGGAC
CAGCCATGAGTGGCTCTTATGGCCAAAGGCGGTACTGCAGGCCAAGCAAACGGCTCTGGGCTGGAATAGCCCTACCTGAGTGCCCTGTTT
GACTCCGCCACTATCTGCCATGTGAGTTGGGCAAATTGTTGACCACCTCTGAGCCTTGAAAAAGTAGGAGGTTACTTTGTTAGAGCAAAA

>In-frame_ENST00000339591_ENST00000580123_TCGA-C8-A26X-01A_ITGB4_chr17_73747192_+_SLC16A5_chr17_73094133_length(amino acids)=1711AA_start in transcript=163_stop in transcript=5298
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFG
KFVDKVSVPQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFS
TESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDS
SNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSD
GLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYE
GQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIH
PGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFW
WLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLRSGNLKGRDVVRWKVTNNMQRPG
FATHAASINPTELVPYGLSLRLARLCTENLLKPDTRECAQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPR
SAKPALLKLTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPAGTATLGRRLVNIT
IIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLR
GRQVRRFHVQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYW
IQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITA
YEVCYGLVNDDNRPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALA
SMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRH
NTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAA
SGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGG
SFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSP

--------------------------------------------------------------
>In-frame_ENST00000200181_ENST00000580123_TCGA-C8-A26X-01A_ITGB4_chr17_73747192_+_SLC16A5_chr17_73094133_length(transcript)=5428nt_BP=3980nt
GCGCTGCCCGCCTCGTCCCCACCCCCCCAACCCCCGCGCCCGCCCTCGGACAGTCCCTGCTCGCCCGCGCGCTGCAGCCCCATCTCCTAG
CGGCAGCCCAGGCGCGGAGGGAGCGAGTCCGCCCCGAGGTAGGTCCAGGACGGGCGCACAGCAGCAGCCGAGGCTGGCCGGGAGAGGGAG
GAAGAGGATGGCAGGGCCACGCCCCAGCCCATGGGCCAGGCTGCTCCTGGCAGCCTTGATCAGCGTCAGCCTCTCTGGGACCTTGGCAAA
CCGCTGCAAGAAGGCCCCAGTGAAGAGCTGCACGGAGTGTGTCCGTGTGGATAAGGACTGCGCCTACTGCACAGACGAGATGTTCAGGGA
CCGGCGCTGCAACACCCAGGCGGAGCTGCTGGCCGCGGGCTGCCAGCGGGAGAGCATCGTGGTCATGGAGAGCAGCTTCCAAATCACAGA
GGAGACCCAGATTGACACCACCCTGCGGCGCAGCCAGATGTCCCCCCAAGGCCTGCGGGTCCGTCTGCGGCCCGGTGAGGAGCGGCATTT
TGAGCTGGAGGTGTTTGAGCCACTGGAGAGCCCCGTGGACCTGTACATCCTCATGGACTTCTCCAACTCCATGTCCGATGATCTGGACAA
CCTCAAGAAGATGGGGCAGAACCTGGCTCGGGTCCTGAGCCAGCTCACCAGCGACTACACTATTGGATTTGGCAAGTTTGTGGACAAAGT
CAGCGTCCCGCAGACGGACATGAGGCCTGAGAAGCTGAAGGAGCCCTGGCCCAACAGTGACCCCCCCTTCTCCTTCAAGAACGTCATCAG
CCTGACAGAAGATGTGGATGAGTTCCGGAATAAACTGCAGGGAGAGCGGATCTCAGGCAACCTGGATGCTCCTGAGGGCGGCTTCGATGC
CATCCTGCAGACAGCTGTGTGCACGAGGGACATTGGCTGGCGCCCGGACAGCACCCACCTGCTGGTCTTCTCCACCGAGTCAGCCTTCCA
CTATGAGGCTGATGGCGCCAACGTGCTGGCTGGCATCATGAGCCGCAACGATGAACGGTGCCACCTGGACACCACGGGCACCTACACCCA
GTACAGGACACAGGACTACCCGTCGGTGCCCACCCTGGTGCGCCTGCTCGCCAAGCACAACATCATCCCCATCTTTGCTGTCACCAACTA
CTCCTATAGCTACTACGAGAAGCTTCACACCTATTTCCCTGTCTCCTCACTGGGGGTGCTGCAGGAGGACTCGTCCAACATCGTGGAGCT
GCTGGAGGAGGCCTTCAATCGGATCCGCTCCAACCTGGACATCCGGGCCCTAGACAGCCCCCGAGGCCTTCGGACAGAGGTCACCTCCAA
GATGTTCCAGAAGACGAGGACTGGGTCCTTTCACATCCGGCGGGGGGAAGTGGGTATATACCAGGTGCAGCTGCGGGCCCTTGAGCACGT
GGATGGGACGCACGTGTGCCAGCTGCCGGAGGACCAGAAGGGCAACATCCATCTGAAACCTTCCTTCTCCGACGGCCTCAAGATGGACGC
GGGCATCATCTGTGATGTGTGCACCTGCGAGCTGCAAAAAGAGGTGCGGTCAGCTCGCTGCAGCTTCAACGGAGACTTCGTGTGCGGACA
GTGTGTGTGCAGCGAGGGCTGGAGTGGCCAGACCTGCAACTGCTCCACCGGCTCTCTGAGTGACATTCAGCCCTGCCTGCGGGAGGGCGA
GGACAAGCCGTGCTCCGGCCGTGGGGAGTGCCAGTGCGGGCACTGTGTGTGCTACGGCGAAGGCCGCTACGAGGGTCAGTTCTGCGAGTA
TGACAACTTCCAGTGTCCCCGCACTTCCGGGTTCCTCTGCAATGACCGAGGACGCTGCTCCATGGGCCAGTGTGTGTGTGAGCCTGGTTG
GACAGGCCCAAGCTGTGACTGTCCCCTCAGCAATGCCACCTGCATCGACAGCAATGGGGGCATCTGTAATGGACGTGGCCACTGTGAGTG
TGGCCGCTGCCACTGCCACCAGCAGTCGCTCTACACGGACACCATCTGCGAGATCAACTACTCGGCGATCCACCCGGGCCTCTGCGAGGA
CCTACGCTCCTGCGTGCAGTGCCAGGCGTGGGGCACCGGCGAGAAGAAGGGGCGCACGTGTGAGGAATGCAACTTCAAGGTCAAGATGGT
GGACGAGCTTAAGAGAGCCGAGGAGGTGGTGGTGCGCTGCTCCTTCCGGGACGAGGATGACGACTGCACCTACAGCTACACCATGGAAGG
TGACGGCGCCCCTGGGCCCAACAGCACTGTCCTGGTGCACAAGAAGAAGGACTGCCCTCCGGGCTCCTTCTGGTGGCTCATCCCCCTGCT
CCTCCTCCTCCTGCCGCTCCTGGCCCTGCTACTGCTGCTATGCTGGAAGTACTGTGCCTGCTGCAAGGCCTGCCTGGCACTTCTCCCGTG
CTGCAACCGAGGTCACATGGTGGGCTTTAAGGAAGACCACTACATGCTGCGGGAGAACCTGATGGCCTCTGACCACTTGGACACGCCCAT
GCTGCGCAGCGGGAACCTCAAGGGCCGTGACGTGGTCCGCTGGAAGGTCACCAACAACATGCAGCGGCCTGGCTTTGCCACTCATGCCGC
CAGCATCAACCCCACAGAGCTGGTGCCCTACGGGCTGTCCTTGCGCCTGGCCCGCCTTTGCACCGAGAACCTGCTGAAGCCTGACACTCG
GGAGTGCGCCCAGCTGCGCCAGGAGGTGGAGGAGAACCTGAACGAGGTCTACAGGCAGATCTCCGGTGTACACAAGCTCCAGCAGACCAA
GTTCCGGCAGCAGCCCAATGCCGGGAAAAAGCAAGACCACACCATTGTGGACACAGTGCTGATGGCGCCCCGCTCGGCCAAGCCGGCCCT
GCTGAAGCTTACAGAGAAGCAGGTGGAACAGAGGGCCTTCCACGACCTCAAGGTGGCCCCCGGCTACTACACCCTCACTGCAGACCAGGA
CGCCCGGGGCATGGTGGAGTTCCAGGAGGGCGTGGAGCTGGTGGACGTACGGGTGCCCCTCTTTATCCGGCCTGAGGATGACGACGAGAA
GCAGCTGCTGGTGGAGGCCATCGACGTGCCCGCAGGCACTGCCACCCTCGGCCGCCGCCTGGTAAACATCACCATCATCAAGGAGCAAGC
CAGAGACGTGGTGTCCTTTGAGCAGCCTGAGTTCTCGGTCAGCCGCGGGGACCAGGTGGCCCGCATCCCTGTCATCCGGCGTGTCCTGGA
CGGCGGGAAGTCCCAGGTCTCCTACCGCACACAGGATGGCACCGCGCAGGGCAACCGGGACTACATCCCCGTGGAGGGTGAGCTGCTGTT
CCAGCCTGGGGAGGCCTGGAAAGAGCTGCAGGTGAAGCTCCTGGAGCTGCAAGAAGTTGACTCCCTCCTGCGGGGCCGCCAGGTCCGCCG
TTTCCACGTCCAGCTCAGCAACCCTAAGTTTGGGGCCCACCTGGGCCAGCCCCACTCCACCACCATCATCATCAGGGACCCAGATGAACT
GGACCGGAGCTTCACGAGTCAGATGTTGTCATCACAGCCACCCCCTCACGGCGACCTGGGCGCCCCGCAGAACCCCAATGCTAAGGCCGC
TGGGTCCAGGAAGATCCATTTCAACTGGCTGCCCCCTTCTGGCAAGCCAATGGGGTACAGGGTAAAGTACTGGATTCAGGGTGACTCCGA
ATCCGAAGCCCACCTGCTCGACAGCAAGGTGCCCTCAGTGGAGCTCACCAACCTGTACCCGTATTGCGACTATGAGATGAAGGTGTGCGC
CTACGGGGCTCAGGGCGAGGGACCCTACAGCTCCCTGGTGTCCTGCCGCACCCACCAGGAAGTGCCCAGCGAGCCAGGGCGTCTGGCCTT
CAATGTCGTCTCCTCCACGGTGACCCAGCTGAGCTGGGCTGAGCCGGCTGAGACCAACGGTGAGATCACAGCCTACGAGGTCTGCTATGG
CCTGGTCAACGATGACAACCGGCCCCTGTGCAGCATCCTGGTGGGACGCTTCGGCTGCCGAGTGACCGTGATGCTGGGGGGCGTGCTGGC
CAGCCTGGGCATGGTGGCCAGCTCCTTCTCTCACAACCTCAGCCAGCTCTACTTCACAGCAGGATTCATCACAGGCCTGGGCATGTGCTT
CAGCTTCCAGTCAAGCATCACGGTGCTGGGCTTCTACTTTGTCCGCCGGCGGGTGCTGGCCAACGCGCTGGCCTCGATGGGCGTCTCCCT
GGGCATCACCCTCTGGCCGCTGCTCTCCCGCTACCTTCTGGAGAACCTGGGCTGGAGGGGTACCTTCCTTGTCTTCGGCGGGATCTTTCT
CCACTGCTGCATCTGCGGGGCCATCATAAGGCCTGTGGCCACCAGTGTGGCCCCTGAGACCAAAGAATGTCCCCCGCCACCTCCCGAGAC
ACCTGCACTTGGCTGCCTGGCTGCATGCGGCCGGACCATCCAGCGCCACCTGGCCTTCGACATCCTGCGGCACAACACAGGCTACTGCGT
GTACATACTGGGTGTGATGTGGTCCGTCCTGGGCTTCCCACTGCCACAAGTCTTCCTGGTGCCATATGCCATGTGGCACAGCGTGGACGA
GCAGCAGGCAGCCCTCCTCATCTCCATCATCGGCTTCAGCAACATCTTCCTGAGGCCCCTAGCCGGGCTGATGGCAGGACGGCCGGCCTT
TGCTAGCCACCGCAAGTACCTGTTCAGCCTGGCACTCCTGCTCAATGGGCTCACTAACCTGGTGTGTGCGGCATCAGGTGACTTCTGGGT
GCTCGTGGGCTACTGCCTGGCGTACAGCGTGTCCATGAGTGGCATCGGCGCCCTCATCTTCCAGGTTCTCATGGACATCGTCCCCATGGA
TCAGTTCCCCAGAGCCCTGGGACTCTTCACTGTCCTGGACGGCCTTGCTTTCCTCATCTCCCCACCACTGGCCGGGTTGCTCCTGGACGC
CACCAACAACTTTAGCTATGTTTTCTACATGTCCAGCTTCTTCCTCATCTCAGCTGCCCTCTTCATGGGTGGCAGCTTCTACGCCCTGCA
GAAGAAGGAGCAAGGCAAGCAGGCTGTCGCGGCGGATGCCCTGGAGCGGGATCTTTTCTTGGAAGCCAAAGACGGTCCTGGGAAGCAACG
GTCCCCTGAGATCATGTGCCAGTCTTCCCGCCAGCCACGTCCAGCTGGCGTCAATAAGCATCTTTGGGGATGTCCTGCCTCCTCCAGGAC
CAGCCATGAGTGGCTCTTATGGCCAAAGGCGGTACTGCAGGCCAAGCAAACGGCTCTGGGCTGGAATAGCCCTACCTGAGTGCCCTGTTT
GACTCCGCCACTATCTGCCATGTGAGTTGGGCAAATTGTTGACCACCTCTGAGCCTTGAAAAAGTAGGAGGTTACTTTGTTAGAGCAAAA

>In-frame_ENST00000200181_ENST00000580123_TCGA-C8-A26X-01A_ITGB4_chr17_73747192_+_SLC16A5_chr17_73094133_length(amino acids)=1711AA_start in transcript=163_stop in transcript=5298
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFG
KFVDKVSVPQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFS
TESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDS
SNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSD
GLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYE
GQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIH
PGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFW
WLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLRSGNLKGRDVVRWKVTNNMQRPG
FATHAASINPTELVPYGLSLRLARLCTENLLKPDTRECAQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPR
SAKPALLKLTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPAGTATLGRRLVNIT
IIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLR
GRQVRRFHVQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYW
IQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITA
YEVCYGLVNDDNRPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALA
SMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRH
NTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAA
SGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGG
SFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSP

--------------------------------------------------------------
>In-frame_ENST00000450894_ENST00000580123_TCGA-C8-A26X-01A_ITGB4_chr17_73747192_+_SLC16A5_chr17_73094133_length(transcript)=5367nt_BP=3919nt
CGCCCGCGCGCTGCAGCCCCATCTCCTAGCGGCAGCCCAGGCGCGGAGGGAGCGAGTCCGCCCCGAGGTAGGTCCAGGACGGGCGCACAG
CAGCAGCCGAGGCTGGCCGGGAGAGGGAGGAAGAGGATGGCAGGGCCACGCCCCAGCCCATGGGCCAGGCTGCTCCTGGCAGCCTTGATC
AGCGTCAGCCTCTCTGGGACCTTGGCAAACCGCTGCAAGAAGGCCCCAGTGAAGAGCTGCACGGAGTGTGTCCGTGTGGATAAGGACTGC
GCCTACTGCACAGACGAGATGTTCAGGGACCGGCGCTGCAACACCCAGGCGGAGCTGCTGGCCGCGGGCTGCCAGCGGGAGAGCATCGTG
GTCATGGAGAGCAGCTTCCAAATCACAGAGGAGACCCAGATTGACACCACCCTGCGGCGCAGCCAGATGTCCCCCCAAGGCCTGCGGGTC
CGTCTGCGGCCCGGTGAGGAGCGGCATTTTGAGCTGGAGGTGTTTGAGCCACTGGAGAGCCCCGTGGACCTGTACATCCTCATGGACTTC
TCCAACTCCATGTCCGATGATCTGGACAACCTCAAGAAGATGGGGCAGAACCTGGCTCGGGTCCTGAGCCAGCTCACCAGCGACTACACT
ATTGGATTTGGCAAGTTTGTGGACAAAGTCAGCGTCCCGCAGACGGACATGAGGCCTGAGAAGCTGAAGGAGCCCTGGCCCAACAGTGAC
CCCCCCTTCTCCTTCAAGAACGTCATCAGCCTGACAGAAGATGTGGATGAGTTCCGGAATAAACTGCAGGGAGAGCGGATCTCAGGCAAC
CTGGATGCTCCTGAGGGCGGCTTCGATGCCATCCTGCAGACAGCTGTGTGCACGAGGGACATTGGCTGGCGCCCGGACAGCACCCACCTG
CTGGTCTTCTCCACCGAGTCAGCCTTCCACTATGAGGCTGATGGCGCCAACGTGCTGGCTGGCATCATGAGCCGCAACGATGAACGGTGC
CACCTGGACACCACGGGCACCTACACCCAGTACAGGACACAGGACTACCCGTCGGTGCCCACCCTGGTGCGCCTGCTCGCCAAGCACAAC
ATCATCCCCATCTTTGCTGTCACCAACTACTCCTATAGCTACTACGAGAAGCTTCACACCTATTTCCCTGTCTCCTCACTGGGGGTGCTG
CAGGAGGACTCGTCCAACATCGTGGAGCTGCTGGAGGAGGCCTTCAATCGGATCCGCTCCAACCTGGACATCCGGGCCCTAGACAGCCCC
CGAGGCCTTCGGACAGAGGTCACCTCCAAGATGTTCCAGAAGACGAGGACTGGGTCCTTTCACATCCGGCGGGGGGAAGTGGGTATATAC
CAGGTGCAGCTGCGGGCCCTTGAGCACGTGGATGGGACGCACGTGTGCCAGCTGCCGGAGGACCAGAAGGGCAACATCCATCTGAAACCT
TCCTTCTCCGACGGCCTCAAGATGGACGCGGGCATCATCTGTGATGTGTGCACCTGCGAGCTGCAAAAAGAGGTGCGGTCAGCTCGCTGC
AGCTTCAACGGAGACTTCGTGTGCGGACAGTGTGTGTGCAGCGAGGGCTGGAGTGGCCAGACCTGCAACTGCTCCACCGGCTCTCTGAGT
GACATTCAGCCCTGCCTGCGGGAGGGCGAGGACAAGCCGTGCTCCGGCCGTGGGGAGTGCCAGTGCGGGCACTGTGTGTGCTACGGCGAA
GGCCGCTACGAGGGTCAGTTCTGCGAGTATGACAACTTCCAGTGTCCCCGCACTTCCGGGTTCCTCTGCAATGACCGAGGACGCTGCTCC
ATGGGCCAGTGTGTGTGTGAGCCTGGTTGGACAGGCCCAAGCTGTGACTGTCCCCTCAGCAATGCCACCTGCATCGACAGCAATGGGGGC
ATCTGTAATGGACGTGGCCACTGTGAGTGTGGCCGCTGCCACTGCCACCAGCAGTCGCTCTACACGGACACCATCTGCGAGATCAACTAC
TCGGCGATCCACCCGGGCCTCTGCGAGGACCTACGCTCCTGCGTGCAGTGCCAGGCGTGGGGCACCGGCGAGAAGAAGGGGCGCACGTGT
GAGGAATGCAACTTCAAGGTCAAGATGGTGGACGAGCTTAAGAGAGCCGAGGAGGTGGTGGTGCGCTGCTCCTTCCGGGACGAGGATGAC
GACTGCACCTACAGCTACACCATGGAAGGTGACGGCGCCCCTGGGCCCAACAGCACTGTCCTGGTGCACAAGAAGAAGGACTGCCCTCCG
GGCTCCTTCTGGTGGCTCATCCCCCTGCTCCTCCTCCTCCTGCCGCTCCTGGCCCTGCTACTGCTGCTATGCTGGAAGTACTGTGCCTGC
TGCAAGGCCTGCCTGGCACTTCTCCCGTGCTGCAACCGAGGTCACATGGTGGGCTTTAAGGAAGACCACTACATGCTGCGGGAGAACCTG
ATGGCCTCTGACCACTTGGACACGCCCATGCTGCGCAGCGGGAACCTCAAGGGCCGTGACGTGGTCCGCTGGAAGGTCACCAACAACATG
CAGCGGCCTGGCTTTGCCACTCATGCCGCCAGCATCAACCCCACAGAGCTGGTGCCCTACGGGCTGTCCTTGCGCCTGGCCCGCCTTTGC
ACCGAGAACCTGCTGAAGCCTGACACTCGGGAGTGCGCCCAGCTGCGCCAGGAGGTGGAGGAGAACCTGAACGAGGTCTACAGGCAGATC
TCCGGTGTACACAAGCTCCAGCAGACCAAGTTCCGGCAGCAGCCCAATGCCGGGAAAAAGCAAGACCACACCATTGTGGACACAGTGCTG
ATGGCGCCCCGCTCGGCCAAGCCGGCCCTGCTGAAGCTTACAGAGAAGCAGGTGGAACAGAGGGCCTTCCACGACCTCAAGGTGGCCCCC
GGCTACTACACCCTCACTGCAGACCAGGACGCCCGGGGCATGGTGGAGTTCCAGGAGGGCGTGGAGCTGGTGGACGTACGGGTGCCCCTC
TTTATCCGGCCTGAGGATGACGACGAGAAGCAGCTGCTGGTGGAGGCCATCGACGTGCCCGCAGGCACTGCCACCCTCGGCCGCCGCCTG
GTAAACATCACCATCATCAAGGAGCAAGCCAGAGACGTGGTGTCCTTTGAGCAGCCTGAGTTCTCGGTCAGCCGCGGGGACCAGGTGGCC
CGCATCCCTGTCATCCGGCGTGTCCTGGACGGCGGGAAGTCCCAGGTCTCCTACCGCACACAGGATGGCACCGCGCAGGGCAACCGGGAC
TACATCCCCGTGGAGGGTGAGCTGCTGTTCCAGCCTGGGGAGGCCTGGAAAGAGCTGCAGGTGAAGCTCCTGGAGCTGCAAGAAGTTGAC
TCCCTCCTGCGGGGCCGCCAGGTCCGCCGTTTCCACGTCCAGCTCAGCAACCCTAAGTTTGGGGCCCACCTGGGCCAGCCCCACTCCACC
ACCATCATCATCAGGGACCCAGATGAACTGGACCGGAGCTTCACGAGTCAGATGTTGTCATCACAGCCACCCCCTCACGGCGACCTGGGC
GCCCCGCAGAACCCCAATGCTAAGGCCGCTGGGTCCAGGAAGATCCATTTCAACTGGCTGCCCCCTTCTGGCAAGCCAATGGGGTACAGG
GTAAAGTACTGGATTCAGGGTGACTCCGAATCCGAAGCCCACCTGCTCGACAGCAAGGTGCCCTCAGTGGAGCTCACCAACCTGTACCCG
TATTGCGACTATGAGATGAAGGTGTGCGCCTACGGGGCTCAGGGCGAGGGACCCTACAGCTCCCTGGTGTCCTGCCGCACCCACCAGGAA
GTGCCCAGCGAGCCAGGGCGTCTGGCCTTCAATGTCGTCTCCTCCACGGTGACCCAGCTGAGCTGGGCTGAGCCGGCTGAGACCAACGGT
GAGATCACAGCCTACGAGGTCTGCTATGGCCTGGTCAACGATGACAACCGGCCCCTGTGCAGCATCCTGGTGGGACGCTTCGGCTGCCGA
GTGACCGTGATGCTGGGGGGCGTGCTGGCCAGCCTGGGCATGGTGGCCAGCTCCTTCTCTCACAACCTCAGCCAGCTCTACTTCACAGCA
GGATTCATCACAGGCCTGGGCATGTGCTTCAGCTTCCAGTCAAGCATCACGGTGCTGGGCTTCTACTTTGTCCGCCGGCGGGTGCTGGCC
AACGCGCTGGCCTCGATGGGCGTCTCCCTGGGCATCACCCTCTGGCCGCTGCTCTCCCGCTACCTTCTGGAGAACCTGGGCTGGAGGGGT
ACCTTCCTTGTCTTCGGCGGGATCTTTCTCCACTGCTGCATCTGCGGGGCCATCATAAGGCCTGTGGCCACCAGTGTGGCCCCTGAGACC
AAAGAATGTCCCCCGCCACCTCCCGAGACACCTGCACTTGGCTGCCTGGCTGCATGCGGCCGGACCATCCAGCGCCACCTGGCCTTCGAC
ATCCTGCGGCACAACACAGGCTACTGCGTGTACATACTGGGTGTGATGTGGTCCGTCCTGGGCTTCCCACTGCCACAAGTCTTCCTGGTG
CCATATGCCATGTGGCACAGCGTGGACGAGCAGCAGGCAGCCCTCCTCATCTCCATCATCGGCTTCAGCAACATCTTCCTGAGGCCCCTA
GCCGGGCTGATGGCAGGACGGCCGGCCTTTGCTAGCCACCGCAAGTACCTGTTCAGCCTGGCACTCCTGCTCAATGGGCTCACTAACCTG
GTGTGTGCGGCATCAGGTGACTTCTGGGTGCTCGTGGGCTACTGCCTGGCGTACAGCGTGTCCATGAGTGGCATCGGCGCCCTCATCTTC
CAGGTTCTCATGGACATCGTCCCCATGGATCAGTTCCCCAGAGCCCTGGGACTCTTCACTGTCCTGGACGGCCTTGCTTTCCTCATCTCC
CCACCACTGGCCGGGTTGCTCCTGGACGCCACCAACAACTTTAGCTATGTTTTCTACATGTCCAGCTTCTTCCTCATCTCAGCTGCCCTC
TTCATGGGTGGCAGCTTCTACGCCCTGCAGAAGAAGGAGCAAGGCAAGCAGGCTGTCGCGGCGGATGCCCTGGAGCGGGATCTTTTCTTG
GAAGCCAAAGACGGTCCTGGGAAGCAACGGTCCCCTGAGATCATGTGCCAGTCTTCCCGCCAGCCACGTCCAGCTGGCGTCAATAAGCAT
CTTTGGGGATGTCCTGCCTCCTCCAGGACCAGCCATGAGTGGCTCTTATGGCCAAAGGCGGTACTGCAGGCCAAGCAAACGGCTCTGGGC
TGGAATAGCCCTACCTGAGTGCCCTGTTTGACTCCGCCACTATCTGCCATGTGAGTTGGGCAAATTGTTGACCACCTCTGAGCCTTGAAA

>In-frame_ENST00000450894_ENST00000580123_TCGA-C8-A26X-01A_ITGB4_chr17_73747192_+_SLC16A5_chr17_73094133_length(amino acids)=1711AA_start in transcript=102_stop in transcript=5237
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFG
KFVDKVSVPQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFS
TESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDS
SNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSD
GLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYE
GQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIH
PGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFW
WLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLRSGNLKGRDVVRWKVTNNMQRPG
FATHAASINPTELVPYGLSLRLARLCTENLLKPDTRECAQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPR
SAKPALLKLTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPAGTATLGRRLVNIT
IIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLR
GRQVRRFHVQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYW
IQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITA
YEVCYGLVNDDNRPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALA
SMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRH
NTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAA
SGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGG
SFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSP

--------------------------------------------------------------
>In-frame_ENST00000449880_ENST00000580123_TCGA-C8-A26X-01A_ITGB4_chr17_73747192_+_SLC16A5_chr17_73094133_length(transcript)=5249nt_BP=3801nt
GGAAGAGGATGGCAGGGCCACGCCCCAGCCCATGGGCCAGGCTGCTCCTGGCAGCCTTGATCAGCGTCAGCCTCTCTGGGACCTTGGCAA
ACCGCTGCAAGAAGGCCCCAGTGAAGAGCTGCACGGAGTGTGTCCGTGTGGATAAGGACTGCGCCTACTGCACAGACGAGATGTTCAGGG
ACCGGCGCTGCAACACCCAGGCGGAGCTGCTGGCCGCGGGCTGCCAGCGGGAGAGCATCGTGGTCATGGAGAGCAGCTTCCAAATCACAG
AGGAGACCCAGATTGACACCACCCTGCGGCGCAGCCAGATGTCCCCCCAAGGCCTGCGGGTCCGTCTGCGGCCCGGTGAGGAGCGGCATT
TTGAGCTGGAGGTGTTTGAGCCACTGGAGAGCCCCGTGGACCTGTACATCCTCATGGACTTCTCCAACTCCATGTCCGATGATCTGGACA
ACCTCAAGAAGATGGGGCAGAACCTGGCTCGGGTCCTGAGCCAGCTCACCAGCGACTACACTATTGGATTTGGCAAGTTTGTGGACAAAG
TCAGCGTCCCGCAGACGGACATGAGGCCTGAGAAGCTGAAGGAGCCCTGGCCCAACAGTGACCCCCCCTTCTCCTTCAAGAACGTCATCA
GCCTGACAGAAGATGTGGATGAGTTCCGGAATAAACTGCAGGGAGAGCGGATCTCAGGCAACCTGGATGCTCCTGAGGGCGGCTTCGATG
CCATCCTGCAGACAGCTGTGTGCACGAGGGACATTGGCTGGCGCCCGGACAGCACCCACCTGCTGGTCTTCTCCACCGAGTCAGCCTTCC
ACTATGAGGCTGATGGCGCCAACGTGCTGGCTGGCATCATGAGCCGCAACGATGAACGGTGCCACCTGGACACCACGGGCACCTACACCC
AGTACAGGACACAGGACTACCCGTCGGTGCCCACCCTGGTGCGCCTGCTCGCCAAGCACAACATCATCCCCATCTTTGCTGTCACCAACT
ACTCCTATAGCTACTACGAGAAGCTTCACACCTATTTCCCTGTCTCCTCACTGGGGGTGCTGCAGGAGGACTCGTCCAACATCGTGGAGC
TGCTGGAGGAGGCCTTCAATCGGATCCGCTCCAACCTGGACATCCGGGCCCTAGACAGCCCCCGAGGCCTTCGGACAGAGGTCACCTCCA
AGATGTTCCAGAAGACGAGGACTGGGTCCTTTCACATCCGGCGGGGGGAAGTGGGTATATACCAGGTGCAGCTGCGGGCCCTTGAGCACG
TGGATGGGACGCACGTGTGCCAGCTGCCGGAGGACCAGAAGGGCAACATCCATCTGAAACCTTCCTTCTCCGACGGCCTCAAGATGGACG
CGGGCATCATCTGTGATGTGTGCACCTGCGAGCTGCAAAAAGAGGTGCGGTCAGCTCGCTGCAGCTTCAACGGAGACTTCGTGTGCGGAC
AGTGTGTGTGCAGCGAGGGCTGGAGTGGCCAGACCTGCAACTGCTCCACCGGCTCTCTGAGTGACATTCAGCCCTGCCTGCGGGAGGGCG
AGGACAAGCCGTGCTCCGGCCGTGGGGAGTGCCAGTGCGGGCACTGTGTGTGCTACGGCGAAGGCCGCTACGAGGGTCAGTTCTGCGAGT
ATGACAACTTCCAGTGTCCCCGCACTTCCGGGTTCCTCTGCAATGACCGAGGACGCTGCTCCATGGGCCAGTGTGTGTGTGAGCCTGGTT
GGACAGGCCCAAGCTGTGACTGTCCCCTCAGCAATGCCACCTGCATCGACAGCAATGGGGGCATCTGTAATGGACGTGGCCACTGTGAGT
GTGGCCGCTGCCACTGCCACCAGCAGTCGCTCTACACGGACACCATCTGCGAGATCAACTACTCGGCGATCCACCCGGGCCTCTGCGAGG
ACCTACGCTCCTGCGTGCAGTGCCAGGCGTGGGGCACCGGCGAGAAGAAGGGGCGCACGTGTGAGGAATGCAACTTCAAGGTCAAGATGG
TGGACGAGCTTAAGAGAGCCGAGGAGGTGGTGGTGCGCTGCTCCTTCCGGGACGAGGATGACGACTGCACCTACAGCTACACCATGGAAG
GTGACGGCGCCCCTGGGCCCAACAGCACTGTCCTGGTGCACAAGAAGAAGGACTGCCCTCCGGGCTCCTTCTGGTGGCTCATCCCCCTGC
TCCTCCTCCTCCTGCCGCTCCTGGCCCTGCTACTGCTGCTATGCTGGAAGTACTGTGCCTGCTGCAAGGCCTGCCTGGCACTTCTCCCGT
GCTGCAACCGAGGTCACATGGTGGGCTTTAAGGAAGACCACTACATGCTGCGGGAGAACCTGATGGCCTCTGACCACTTGGACACGCCCA
TGCTGCGCAGCGGGAACCTCAAGGGCCGTGACGTGGTCCGCTGGAAGGTCACCAACAACATGCAGCGGCCTGGCTTTGCCACTCATGCCG
CCAGCATCAACCCCACAGAGCTGGTGCCCTACGGGCTGTCCTTGCGCCTGGCCCGCCTTTGCACCGAGAACCTGCTGAAGCCTGACACTC
GGGAGTGCGCCCAGCTGCGCCAGGAGGTGGAGGAGAACCTGAACGAGGTCTACAGGCAGATCTCCGGTGTACACAAGCTCCAGCAGACCA
AGTTCCGGCAGCAGCCCAATGCCGGGAAAAAGCAAGACCACACCATTGTGGACACAGTGCTGATGGCGCCCCGCTCGGCCAAGCCGGCCC
TGCTGAAGCTTACAGAGAAGCAGGTGGAACAGAGGGCCTTCCACGACCTCAAGGTGGCCCCCGGCTACTACACCCTCACTGCAGACCAGG
ACGCCCGGGGCATGGTGGAGTTCCAGGAGGGCGTGGAGCTGGTGGACGTACGGGTGCCCCTCTTTATCCGGCCTGAGGATGACGACGAGA
AGCAGCTGCTGGTGGAGGCCATCGACGTGCCCGCAGGCACTGCCACCCTCGGCCGCCGCCTGGTAAACATCACCATCATCAAGGAGCAAG
CCAGAGACGTGGTGTCCTTTGAGCAGCCTGAGTTCTCGGTCAGCCGCGGGGACCAGGTGGCCCGCATCCCTGTCATCCGGCGTGTCCTGG
ACGGCGGGAAGTCCCAGGTCTCCTACCGCACACAGGATGGCACCGCGCAGGGCAACCGGGACTACATCCCCGTGGAGGGTGAGCTGCTGT
TCCAGCCTGGGGAGGCCTGGAAAGAGCTGCAGGTGAAGCTCCTGGAGCTGCAAGAAGTTGACTCCCTCCTGCGGGGCCGCCAGGTCCGCC
GTTTCCACGTCCAGCTCAGCAACCCTAAGTTTGGGGCCCACCTGGGCCAGCCCCACTCCACCACCATCATCATCAGGGACCCAGATGAAC
TGGACCGGAGCTTCACGAGTCAGATGTTGTCATCACAGCCACCCCCTCACGGCGACCTGGGCGCCCCGCAGAACCCCAATGCTAAGGCCG
CTGGGTCCAGGAAGATCCATTTCAACTGGCTGCCCCCTTCTGGCAAGCCAATGGGGTACAGGGTAAAGTACTGGATTCAGGGTGACTCCG
AATCCGAAGCCCACCTGCTCGACAGCAAGGTGCCCTCAGTGGAGCTCACCAACCTGTACCCGTATTGCGACTATGAGATGAAGGTGTGCG
CCTACGGGGCTCAGGGCGAGGGACCCTACAGCTCCCTGGTGTCCTGCCGCACCCACCAGGAAGTGCCCAGCGAGCCAGGGCGTCTGGCCT
TCAATGTCGTCTCCTCCACGGTGACCCAGCTGAGCTGGGCTGAGCCGGCTGAGACCAACGGTGAGATCACAGCCTACGAGGTCTGCTATG
GCCTGGTCAACGATGACAACCGGCCCCTGTGCAGCATCCTGGTGGGACGCTTCGGCTGCCGAGTGACCGTGATGCTGGGGGGCGTGCTGG
CCAGCCTGGGCATGGTGGCCAGCTCCTTCTCTCACAACCTCAGCCAGCTCTACTTCACAGCAGGATTCATCACAGGCCTGGGCATGTGCT
TCAGCTTCCAGTCAAGCATCACGGTGCTGGGCTTCTACTTTGTCCGCCGGCGGGTGCTGGCCAACGCGCTGGCCTCGATGGGCGTCTCCC
TGGGCATCACCCTCTGGCCGCTGCTCTCCCGCTACCTTCTGGAGAACCTGGGCTGGAGGGGTACCTTCCTTGTCTTCGGCGGGATCTTTC
TCCACTGCTGCATCTGCGGGGCCATCATAAGGCCTGTGGCCACCAGTGTGGCCCCTGAGACCAAAGAATGTCCCCCGCCACCTCCCGAGA
CACCTGCACTTGGCTGCCTGGCTGCATGCGGCCGGACCATCCAGCGCCACCTGGCCTTCGACATCCTGCGGCACAACACAGGCTACTGCG
TGTACATACTGGGTGTGATGTGGTCCGTCCTGGGCTTCCCACTGCCACAAGTCTTCCTGGTGCCATATGCCATGTGGCACAGCGTGGACG
AGCAGCAGGCAGCCCTCCTCATCTCCATCATCGGCTTCAGCAACATCTTCCTGAGGCCCCTAGCCGGGCTGATGGCAGGACGGCCGGCCT
TTGCTAGCCACCGCAAGTACCTGTTCAGCCTGGCACTCCTGCTCAATGGGCTCACTAACCTGGTGTGTGCGGCATCAGGTGACTTCTGGG
TGCTCGTGGGCTACTGCCTGGCGTACAGCGTGTCCATGAGTGGCATCGGCGCCCTCATCTTCCAGGTTCTCATGGACATCGTCCCCATGG
ATCAGTTCCCCAGAGCCCTGGGACTCTTCACTGTCCTGGACGGCCTTGCTTTCCTCATCTCCCCACCACTGGCCGGGTTGCTCCTGGACG
CCACCAACAACTTTAGCTATGTTTTCTACATGTCCAGCTTCTTCCTCATCTCAGCTGCCCTCTTCATGGGTGGCAGCTTCTACGCCCTGC
AGAAGAAGGAGCAAGGCAAGCAGGCTGTCGCGGCGGATGCCCTGGAGCGGGATCTTTTCTTGGAAGCCAAAGACGGTCCTGGGAAGCAAC
GGTCCCCTGAGATCATGTGCCAGTCTTCCCGCCAGCCACGTCCAGCTGGCGTCAATAAGCATCTTTGGGGATGTCCTGCCTCCTCCAGGA
CCAGCCATGAGTGGCTCTTATGGCCAAAGGCGGTACTGCAGGCCAAGCAAACGGCTCTGGGCTGGAATAGCCCTACCTGAGTGCCCTGTT
TGACTCCGCCACTATCTGCCATGTGAGTTGGGCAAATTGTTGACCACCTCTGAGCCTTGAAAAAGTAGGAGGTTACTTTGTTAGAGCAAA

>In-frame_ENST00000449880_ENST00000580123_TCGA-C8-A26X-01A_ITGB4_chr17_73747192_+_SLC16A5_chr17_73094133_length(amino acids)=1703AA_start in transcript=8_stop in transcript=5119
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITEET
QIDTTLRRSQMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYE
ADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSDGLKMDAGI
ICDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLR
SCVQCQAWGTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLRSGNLKGRDVVRWKVTNNMQRPGFATHAASI
NPTELVPYGLSLRLARLCTENLLKPDTRECAQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPAGTATLGRRLVNITIIKEQARD
VVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESE
AHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
NDDNRPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGI
TLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYI
LGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLV
GYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQKK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ITGB4-SLC16A5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ITGB4-SLC16A5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ITGB4-SLC16A5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneITGB4C1856934Epidermolysis bullosa with pyloric atresia11CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneITGB4C0266159Pyloric Atresia2CTD_human
HgeneITGB4C0268374Adult junctional epidermolysis bullosa (disorder)2CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneITGB4C0282160Aplasia Cutis Congenita2CTD_human;ORPHANET
HgeneITGB4C0000786Spontaneous abortion1CTD_human
HgeneITGB4C0000822Abortion, Tubal1CTD_human
HgeneITGB4C0007131Non-Small Cell Lung Carcinoma1CTD_human
HgeneITGB4C0010606Adenoid Cystic Carcinoma1CTD_human
HgeneITGB4C0013575Ectodermal Dysplasia1CTD_human
HgeneITGB4C0014527Epidermolysis Bullosa1CTD_human
HgeneITGB4C0017639Gliosis1CTD_human
HgeneITGB4C0036095Salivary Gland Neoplasms1CTD_human
HgeneITGB4C0079297Epidermolysis Bullosa Progressiva1CTD_human
HgeneITGB4C0079301Junctional Epidermolysis Bullosa1CTD_human
HgeneITGB4C0079683Herlitz Disease1CTD_human
HgeneITGB4C0162361Hidrotic Ectodermal Dysplasia1CTD_human
HgeneITGB4C0220636Malignant neoplasm of salivary gland1CTD_human
HgeneITGB4C1706004Anhydrotic Ectodermal Dysplasias1CTD_human
HgeneITGB4C3830362Early Pregnancy Loss1CTD_human
HgeneITGB4C3887640Astrocytosis1CTD_human
HgeneITGB4C4552766Miscarriage1CTD_human