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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ITSN1-SH3BGR (FusionGDB2 ID:40582)

Fusion Gene Summary for ITSN1-SH3BGR

check button Fusion gene summary
Fusion gene informationFusion gene name: ITSN1-SH3BGR
Fusion gene ID: 40582
HgeneTgene
Gene symbol

ITSN1

SH3BGR

Gene ID

6453

6451

Gene nameintersectin 1SH3 domain binding glutamate rich protein like
SynonymsITSN|SH3D1A|SH3P17HEL-S-115|SH3BGR
Cytomap

21q22.11

Xq21.1

Type of geneprotein-codingprotein-coding
Descriptionintersectin-1SH3 domain-containing protein 1ASrc homology 3 domain-containing proteinhuman intersectin-SH3 domain-containing protein SH3P17intersectin 1 (SH3 domain protein)intersectin 1 short form variant 3intersectin 1 short form variant, 11interSH3 domain-binding glutamic acid-rich-like proteinSH3 domain binding glutamic acid-rich protein likeSH3-binding domain glutamic acid-rich protein likeepididymis secretory protein Li 115
Modification date2020031320200313
UniProtAcc

Q15811

.
Ensembl transtripts involved in fusion geneENST00000399353, ENST00000381318, 
ENST00000381291, ENST00000381285, 
ENST00000399367, ENST00000399352, 
ENST00000399355, ENST00000399349, 
ENST00000399338, ENST00000379960, 
ENST00000437442, ENST00000399326, 
ENST00000488166, 		ENST00000380637, 
ENST00000380634, ENST00000458295, 
ENST00000380631, ENST00000333634, 
Fusion gene scores* DoF score24 X 15 X 9=32408 X 7 X 6=336
# samples 269
** MAII scorelog2(26/3240*10)=-3.63941028474353
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/336*10)=-1.90046432644909
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ITSN1 [Title/Abstract] AND SH3BGR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointITSN1(35172233)-SH3BGR(40871749), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ITSN1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across SH3BGR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8365-01AITSN1chr21

35172233

+SH3BGRchr21

40871749

+


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Fusion Gene ORF analysis for ITSN1-SH3BGR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000399353ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399353ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399353ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399353ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399353ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000381318ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000381318ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000381318ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000381318ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000381318ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000381291ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000381291ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000381291ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000381291ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000381291ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
Frame-shiftENST00000381285ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
Frame-shiftENST00000381285ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000381285ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000381285ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000381285ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399367ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399367ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399367ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399367ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399367ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399352ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399352ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399352ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399352ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399352ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399355ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399355ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399355ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399355ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399355ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399349ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399349ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399349ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399349ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399349ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399338ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399338ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399338ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399338ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399338ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000379960ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000379960ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000379960ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000379960ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000379960ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000437442ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000437442ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000437442ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000437442ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000437442ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399326ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
In-frameENST00000399326ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399326ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399326ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
5CDS-intronENST00000399326ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
intron-3CDSENST00000488166ENST00000380637ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
intron-3CDSENST00000488166ENST00000380634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
intron-intronENST00000488166ENST00000458295ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
intron-intronENST00000488166ENST00000380631ITSN1chr21

35172233

+SH3BGRchr21

40871749

+
intron-intronENST00000488166ENST00000333634ITSN1chr21

35172233

+SH3BGRchr21

40871749

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000399353ITSN1chr2135172233+ENST00000380637SH3BGRchr2140871749+321125393462757803
ENST00000399353ITSN1chr2135172233+ENST00000380634SH3BGRchr2140871749+306025393462757803
ENST00000381318ITSN1chr2135172233+ENST00000380637SH3BGRchr2140871749+326425922882810840
ENST00000381318ITSN1chr2135172233+ENST00000380634SH3BGRchr2140871749+311325922882810840
ENST00000381291ITSN1chr2135172233+ENST00000380637SH3BGRchr2140871749+324425722682790840
ENST00000381291ITSN1chr2135172233+ENST00000380634SH3BGRchr2140871749+309325722682790840
ENST00000399367ITSN1chr2135172233+ENST00000380637SH3BGRchr2140871749+323925672632785840
ENST00000399367ITSN1chr2135172233+ENST00000380634SH3BGRchr2140871749+308825672632785840
ENST00000399352ITSN1chr2135172233+ENST00000380637SH3BGRchr2140871749+322625542502772840
ENST00000399352ITSN1chr2135172233+ENST00000380634SH3BGRchr2140871749+307525542502772840
ENST00000399355ITSN1chr2135172233+ENST00000380637SH3BGRchr2140871749+322425522482770840
ENST00000399355ITSN1chr2135172233+ENST00000380634SH3BGRchr2140871749+307325522482770840
ENST00000399349ITSN1chr2135172233+ENST00000380637SH3BGRchr2140871749+322425522482770840
ENST00000399349ITSN1chr2135172233+ENST00000380634SH3BGRchr2140871749+307325522482770840
ENST00000399338ITSN1chr2135172233+ENST00000380637SH3BGRchr2140871749+29952323192541840
ENST00000399338ITSN1chr2135172233+ENST00000380634SH3BGRchr2140871749+28442323192541840
ENST00000379960ITSN1chr2135172233+ENST00000380637SH3BGRchr2140871749+2977230512523840
ENST00000379960ITSN1chr2135172233+ENST00000380634SH3BGRchr2140871749+2826230512523840
ENST00000437442ITSN1chr2135172233+ENST00000380637SH3BGRchr2140871749+2977230512523840
ENST00000437442ITSN1chr2135172233+ENST00000380634SH3BGRchr2140871749+2826230512523840
ENST00000399326ITSN1chr2135172233+ENST00000380637SH3BGRchr2140871749+2977230512523840
ENST00000399326ITSN1chr2135172233+ENST00000380634SH3BGRchr2140871749+2826230512523840

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000399353ENST00000380637ITSN1chr2135172233+SH3BGRchr2140871749+0.016466840.9835331
ENST00000399353ENST00000380634ITSN1chr2135172233+SH3BGRchr2140871749+0.018152410.9818475
ENST00000381318ENST00000380637ITSN1chr2135172233+SH3BGRchr2140871749+0.0145323280.9854676
ENST00000381318ENST00000380634ITSN1chr2135172233+SH3BGRchr2140871749+0.0176286030.9823714
ENST00000381291ENST00000380637ITSN1chr2135172233+SH3BGRchr2140871749+0.0145431840.9854569
ENST00000381291ENST00000380634ITSN1chr2135172233+SH3BGRchr2140871749+0.0177919770.9822081
ENST00000399367ENST00000380637ITSN1chr2135172233+SH3BGRchr2140871749+0.0146587070.98534125
ENST00000399367ENST00000380634ITSN1chr2135172233+SH3BGRchr2140871749+0.0179991180.9820009
ENST00000399352ENST00000380637ITSN1chr2135172233+SH3BGRchr2140871749+0.0148952410.98510474
ENST00000399352ENST00000380634ITSN1chr2135172233+SH3BGRchr2140871749+0.0182219450.981778
ENST00000399355ENST00000380637ITSN1chr2135172233+SH3BGRchr2140871749+0.0147915360.9852085
ENST00000399355ENST00000380634ITSN1chr2135172233+SH3BGRchr2140871749+0.01807550.9819244
ENST00000399349ENST00000380637ITSN1chr2135172233+SH3BGRchr2140871749+0.0147915360.9852085
ENST00000399349ENST00000380634ITSN1chr2135172233+SH3BGRchr2140871749+0.01807550.9819244
ENST00000399338ENST00000380637ITSN1chr2135172233+SH3BGRchr2140871749+0.0150304610.9849695
ENST00000399338ENST00000380634ITSN1chr2135172233+SH3BGRchr2140871749+0.0193437190.98065627
ENST00000379960ENST00000380637ITSN1chr2135172233+SH3BGRchr2140871749+0.0153275570.9846725
ENST00000379960ENST00000380634ITSN1chr2135172233+SH3BGRchr2140871749+0.0196321680.9803679
ENST00000437442ENST00000380637ITSN1chr2135172233+SH3BGRchr2140871749+0.0153275570.9846725
ENST00000437442ENST00000380634ITSN1chr2135172233+SH3BGRchr2140871749+0.0196321680.9803679
ENST00000399326ENST00000380637ITSN1chr2135172233+SH3BGRchr2140871749+0.0153275570.9846725
ENST00000399326ENST00000380634ITSN1chr2135172233+SH3BGRchr2140871749+0.0196321680.9803679

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Fusion Genomic Features for ITSN1-SH3BGR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ITSN1chr2135172237+SH3BGRchr2140871748+0.000111280.99988866
ITSN1chr2135172237+SH3BGRchr2140871748+0.000111280.99988866

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ITSN1-SH3BGR


check button Go to

FGviewer for the breakpoints of chr21:35172233-chr21:40871749

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ITSN1

Q15811

.
FUNCTION: Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery (PubMed:11584276, PubMed:29887380). Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (PubMed:11584276). Plays a role in the assembly and maturation of clathrin-coated vesicles (By similarity). Recruits FCHSD2 to clathrin-coated pits (PubMed:29887380). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (By similarity). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2 (PubMed:22648170). Promotes ubiquitination and subsequent degradation of EGFR, and thereby contributes to the down-regulation of EGFR-dependent signaling pathways. In chromaffin cells, required for normal exocytosis of catecholamines. Required for rapid replenishment of release-ready synaptic vesicles at presynaptic active zones (By similarity). Inhibits ARHGAP31 activity toward RAC1 (PubMed:11744688). {ECO:0000250|UniProtKB:Q9WVE9, ECO:0000250|UniProtKB:Q9Z0R4, ECO:0000269|PubMed:11584276, ECO:0000269|PubMed:11744688, ECO:0000269|PubMed:22648170, ECO:0000269|PubMed:29887380}.; FUNCTION: [Isoform 1]: Plays a role in synaptic vesicle endocytosis in brain neurons. {ECO:0000250|UniProtKB:Q9Z0R4}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+1825267_278768.0960.6666666666666Calcium binding2
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+182566_77768.0960.6666666666666Calcium binding1
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+1930267_278768.01221.0Calcium binding2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+193066_77768.01221.0Calcium binding1
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+1940267_278768.01722.0Calcium binding2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+194066_77768.01722.0Calcium binding1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+1837267_278768.01091.3333333333333Calcium binding2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+183766_77768.01091.3333333333333Calcium binding1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+1821267_278768.01021.0Calcium binding2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+182166_77768.01021.0Calcium binding1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+1927267_278768.01145.0Calcium binding2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+192766_77768.01145.0Calcium binding1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+1929267_278768.01216.0Calcium binding2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+192966_77768.01216.0Calcium binding1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+1929267_278731.01179.0Calcium binding2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+192966_77731.01179.0Calcium binding1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+1939267_278768.01717.0Calcium binding2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+193966_77768.01717.0Calcium binding1
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+1837267_278768.01661.0Calcium binding2
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+183766_77768.01661.0Calcium binding1
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+1825355_659768.0960.6666666666666Coiled coilOntology_term=ECO:0000255
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+1930355_659768.01221.0Coiled coilOntology_term=ECO:0000255
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+1940355_659768.01722.0Coiled coilOntology_term=ECO:0000255
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+1837355_659768.01091.3333333333333Coiled coilOntology_term=ECO:0000255
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+1821355_659768.01021.0Coiled coilOntology_term=ECO:0000255
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+1927355_659768.01145.0Coiled coilOntology_term=ECO:0000255
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+1929355_659768.01216.0Coiled coilOntology_term=ECO:0000255
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+1929355_659731.01179.0Coiled coilOntology_term=ECO:0000255
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+1939355_659768.01717.0Coiled coilOntology_term=ECO:0000255
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+1837355_659768.01661.0Coiled coilOntology_term=ECO:0000255
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+182521_109768.0960.6666666666666DomainEH 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+1825221_310768.0960.6666666666666DomainEH 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+1825254_289768.0960.6666666666666DomainEF-hand 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+182553_88768.0960.6666666666666DomainEF-hand 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+193021_109768.01221.0DomainEH 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+1930221_310768.01221.0DomainEH 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+1930254_289768.01221.0DomainEF-hand 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+193053_88768.01221.0DomainEF-hand 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+194021_109768.01722.0DomainEH 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+1940221_310768.01722.0DomainEH 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+1940254_289768.01722.0DomainEF-hand 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+194053_88768.01722.0DomainEF-hand 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+183721_109768.01091.3333333333333DomainEH 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+1837221_310768.01091.3333333333333DomainEH 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+1837254_289768.01091.3333333333333DomainEF-hand 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+183753_88768.01091.3333333333333DomainEF-hand 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+182121_109768.01021.0DomainEH 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+1821221_310768.01021.0DomainEH 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+1821254_289768.01021.0DomainEF-hand 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+182153_88768.01021.0DomainEF-hand 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+192721_109768.01145.0DomainEH 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+1927221_310768.01145.0DomainEH 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+1927254_289768.01145.0DomainEF-hand 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+192753_88768.01145.0DomainEF-hand 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+192921_109768.01216.0DomainEH 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+1929221_310768.01216.0DomainEH 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+1929254_289768.01216.0DomainEF-hand 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+192953_88768.01216.0DomainEF-hand 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+192921_109731.01179.0DomainEH 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+1929221_310731.01179.0DomainEH 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+1929254_289731.01179.0DomainEF-hand 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+192953_88731.01179.0DomainEF-hand 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+193921_109768.01717.0DomainEH 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+1939221_310768.01717.0DomainEH 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+1939254_289768.01717.0DomainEF-hand 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+193953_88768.01717.0DomainEF-hand 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+183721_109768.01661.0DomainEH 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+1837221_310768.01661.0DomainEH 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+1837254_289768.01661.0DomainEF-hand 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+183753_88768.01661.0DomainEF-hand 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+1825326_702768.0960.6666666666666RegionNote=KLERQ
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+1930326_702768.01221.0RegionNote=KLERQ
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+1940326_702768.01722.0RegionNote=KLERQ
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+1837326_702768.01091.3333333333333RegionNote=KLERQ
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+1821326_702768.01021.0RegionNote=KLERQ
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+1927326_702768.01145.0RegionNote=KLERQ
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+1929326_702768.01216.0RegionNote=KLERQ
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+1929326_702731.01179.0RegionNote=KLERQ
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+1939326_702768.01717.0RegionNote=KLERQ
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+1837326_702768.01661.0RegionNote=KLERQ
TgeneSH3BGRchr21:35172233chr21:40871749ENST0000033363427170_239167.0275.6666666666667Compositional biasNote=Glu-rich (acidic)
TgeneSH3BGRchr21:35172233chr21:40871749ENST0000038063127170_23956.0122.33333333333333Compositional biasNote=Glu-rich (acidic)
TgeneSH3BGRchr21:35172233chr21:40871749ENST0000038063427170_23956.0209.0Compositional biasNote=Glu-rich (acidic)
TgeneSH3BGRchr21:35172233chr21:40871749ENST0000038063727170_23956.0243.66666666666666Compositional biasNote=Glu-rich (acidic)
TgeneSH3BGRchr21:35172233chr21:40871749ENST0000038063127124_13056.0122.33333333333333MotifSH3-binding
TgeneSH3BGRchr21:35172233chr21:40871749ENST0000038063427124_13056.0209.0MotifSH3-binding
TgeneSH3BGRchr21:35172233chr21:40871749ENST0000038063727124_13056.0243.66666666666666MotifSH3-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+18251002_1060768.0960.6666666666666DomainSH3 3
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+18251155_1214768.0960.6666666666666DomainSH3 5
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+18251237_1423768.0960.6666666666666DomainDH
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+18251462_1571768.0960.6666666666666DomainPH
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+18251579_1695768.0960.6666666666666DomainC2
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+1825740_806768.0960.6666666666666DomainSH3 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+1825913_971768.0960.6666666666666DomainSH3 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+19301002_1060768.01221.0DomainSH3 3
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+19301155_1214768.01221.0DomainSH3 5
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+19301237_1423768.01221.0DomainDH
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+19301462_1571768.01221.0DomainPH
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+19301579_1695768.01221.0DomainC2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+1930740_806768.01221.0DomainSH3 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+1930913_971768.01221.0DomainSH3 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+19401002_1060768.01722.0DomainSH3 3
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+19401155_1214768.01722.0DomainSH3 5
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+19401237_1423768.01722.0DomainDH
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+19401462_1571768.01722.0DomainPH
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+19401579_1695768.01722.0DomainC2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+1940740_806768.01722.0DomainSH3 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+1940913_971768.01722.0DomainSH3 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+18371002_1060768.01091.3333333333333DomainSH3 3
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+18371155_1214768.01091.3333333333333DomainSH3 5
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+18371237_1423768.01091.3333333333333DomainDH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+18371462_1571768.01091.3333333333333DomainPH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+18371579_1695768.01091.3333333333333DomainC2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+1837740_806768.01091.3333333333333DomainSH3 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+1837913_971768.01091.3333333333333DomainSH3 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+18211002_1060768.01021.0DomainSH3 3
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+18211155_1214768.01021.0DomainSH3 5
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+18211237_1423768.01021.0DomainDH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+18211462_1571768.01021.0DomainPH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+18211579_1695768.01021.0DomainC2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+1821740_806768.01021.0DomainSH3 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+1821913_971768.01021.0DomainSH3 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+19271002_1060768.01145.0DomainSH3 3
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+19271155_1214768.01145.0DomainSH3 5
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+19271237_1423768.01145.0DomainDH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+19271462_1571768.01145.0DomainPH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+19271579_1695768.01145.0DomainC2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+1927740_806768.01145.0DomainSH3 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+1927913_971768.01145.0DomainSH3 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+19291002_1060768.01216.0DomainSH3 3
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+19291155_1214768.01216.0DomainSH3 5
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+19291237_1423768.01216.0DomainDH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+19291462_1571768.01216.0DomainPH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+19291579_1695768.01216.0DomainC2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+1929740_806768.01216.0DomainSH3 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+1929913_971768.01216.0DomainSH3 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+19291002_1060731.01179.0DomainSH3 3
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+19291155_1214731.01179.0DomainSH3 5
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+19291237_1423731.01179.0DomainDH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+19291462_1571731.01179.0DomainPH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+19291579_1695731.01179.0DomainC2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+1929740_806731.01179.0DomainSH3 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+1929913_971731.01179.0DomainSH3 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+19391002_1060768.01717.0DomainSH3 3
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+19391155_1214768.01717.0DomainSH3 5
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+19391237_1423768.01717.0DomainDH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+19391462_1571768.01717.0DomainPH
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+19391579_1695768.01717.0DomainC2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+1939740_806768.01717.0DomainSH3 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+1939913_971768.01717.0DomainSH3 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+18371002_1060768.01661.0DomainSH3 3
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+18371155_1214768.01661.0DomainSH3 5
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+18371237_1423768.01661.0DomainDH
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+18371462_1571768.01661.0DomainPH
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+18371579_1695768.01661.0DomainC2
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+1837740_806768.01661.0DomainSH3 1
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+1837913_971768.01661.0DomainSH3 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000379960+18251104_1127768.0960.6666666666666MotifBipartite nuclear localization signal%3B in isoform 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381291+19301104_1127768.01221.0MotifBipartite nuclear localization signal%3B in isoform 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000381318+19401104_1127768.01722.0MotifBipartite nuclear localization signal%3B in isoform 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399326+18371104_1127768.01091.3333333333333MotifBipartite nuclear localization signal%3B in isoform 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399338+18211104_1127768.01021.0MotifBipartite nuclear localization signal%3B in isoform 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399349+19271104_1127768.01145.0MotifBipartite nuclear localization signal%3B in isoform 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399352+19291104_1127768.01216.0MotifBipartite nuclear localization signal%3B in isoform 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399353+19291104_1127731.01179.0MotifBipartite nuclear localization signal%3B in isoform 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000399367+19391104_1127768.01717.0MotifBipartite nuclear localization signal%3B in isoform 2
HgeneITSN1chr21:35172233chr21:40871749ENST00000437442+18371104_1127768.01661.0MotifBipartite nuclear localization signal%3B in isoform 2
TgeneSH3BGRchr21:35172233chr21:40871749ENST0000033363427124_130167.0275.6666666666667MotifSH3-binding


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Fusion Gene Sequence for ITSN1-SH3BGR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000399353_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3211nt_BP=2539nt
ACTTATGGGCGGAGATGGATGGTGGATGGGGGGCGGGGGAGGCAGCGGAGGGAGATGAGGAGATAGGCGGGAGCGAGGGAGCGAGGGAGG
GAGCGAAGGAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCGAGGAAGAATCCC
GAGCGGGCTCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCGCGTGAGCGGCAC
TGATTTGTCCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCATGGCTCAGTTTCC
AACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAGTTTAAAGCCAAT
ATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGATATGGGCACTAGC
TGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGGATATCAGCTACC
CTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGCAGCTGTGCCCCCCCTGGCTAACGGGGC
TCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTC
ACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAG
ACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTC
AAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGAGGAATTTATCCTGGC
AATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCG
ATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGATGAACAACAACAATT
AGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCT
CCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGA
GCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGA
GAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAA
CAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGATAAAAAGCATCAACT
AGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGC
CGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGATACTCAATGACCAATT
AAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCT
ACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGATATTTTCAATAATCAGCTGAAGGAACTAAGAGA
AATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACGAAAGATCATAGAATT
AGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAG
ACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACA
AGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACT
TACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGATGAAATCACTATCCA
GCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCT
CCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGC
CGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCC
AGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAAGCCGGCACACCCAGG
GTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGAATCATACAAAATTAAATGTGAAGACCGTTTATG
CATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCTCTGCATAGCTAGACCATCTTATTAATAATACTC
TGAAAAAAATGATTTCAAGGCATGGAAGTTCTCTGTGATACAACAATAGTATTTCTTCAAATGCGCCTTATGCTACTTATCTCAGAAACA

>In-frame_ENST00000399353_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=803AA_start in transcript=346_stop in transcript=2757
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAV
PQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPS
FRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERE
RQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALND
KKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKEL
ARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQE
DEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHD

--------------------------------------------------------------
>In-frame_ENST00000399353_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3060nt_BP=2539nt
ACTTATGGGCGGAGATGGATGGTGGATGGGGGGCGGGGGAGGCAGCGGAGGGAGATGAGGAGATAGGCGGGAGCGAGGGAGCGAGGGAGG
GAGCGAAGGAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCGAGGAAGAATCCC
GAGCGGGCTCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCGCGTGAGCGGCAC
TGATTTGTCCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCATGGCTCAGTTTCC
AACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAGTTTAAAGCCAAT
ATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGATATGGGCACTAGC
TGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGGATATCAGCTACC
CTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGCAGCTGTGCCCCCCCTGGCTAACGGGGC
TCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTC
ACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAG
ACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTC
AAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGAGGAATTTATCCTGGC
AATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCG
ATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGATGAACAACAACAATT
AGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCT
CCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGA
GCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGA
GAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAA
CAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGATAAAAAGCATCAACT
AGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGC
CGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGATACTCAATGACCAATT
AAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCT
ACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGATATTTTCAATAATCAGCTGAAGGAACTAAGAGA
AATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACGAAAGATCATAGAATT
AGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAG
ACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACA
AGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACT
TACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGATGAAATCACTATCCA
GCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCT
CCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGC
CGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCC
AGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAAGCCGGCACACCCAGG
GTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGAATCATACAAAATTAAATGTGAAGACCGTTTATG
CATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCTCTGCATAGCTAGACCATCTTATTAATAATACTC

>In-frame_ENST00000399353_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=803AA_start in transcript=346_stop in transcript=2757
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAV
PQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPS
FRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERE
RQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALND
KKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKEL
ARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQE
DEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHD

--------------------------------------------------------------
>In-frame_ENST00000381318_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3264nt_BP=2592nt
GGAGATAGGCGGGAGCGAGGGAGCGAGGGAGGGAGCGAAGGAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCT
CCGTAGTACGGCGGCTCGCGAGGAAGAATCCCGAGCGGGCTCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTC
CTGCGTCCCTCCCAGCGGCGCGTGAGCGGCACTGATTTGTCCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAA
GGTAAAAGTAACAGAACCATGGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAG
CATGATCAGCAGTTCCATAGTTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCT
CAACCTGTTTTAGCACAGATATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTT
ATCAAACTGAAGCTACAAGGATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCA
TTTGGTATGGGAGGTATCGCCAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCA
ACCCTAGTATCTTCTGTTCCCACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCAT
CCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTT
GATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAA
ACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAAT
CTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCA
CTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCT
GTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAG
CGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCC
CAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAA
AAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAA
CGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAG
AAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACC
ACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCT
CAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCA
CTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGA
TCAAAACTACAGGAGATTGATATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCC
ATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAG
GAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGG
GAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAA
CCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTAT
TACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAA
GAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAG
ACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCT
GGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCT
CTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATG
TACATGGAGGTATCTCCCGAATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAG
ATTTTTTTTTCTTTTTTGCTCTGCATAGCTAGACCATCTTATTAATAATACTCTGAAAAAAATGATTTCAAGGCATGGAAGTTCTCTGTG
ATACAACAATAGTATTTCTTCAAATGCGCCTTATGCTACTTATCTCAGAAACAGGTTTTAAAATGAAGTGCTTTCCAGAGAACCATCATA

>In-frame_ENST00000381318_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=288_stop in transcript=2810
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000381318_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3113nt_BP=2592nt
GGAGATAGGCGGGAGCGAGGGAGCGAGGGAGGGAGCGAAGGAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCT
CCGTAGTACGGCGGCTCGCGAGGAAGAATCCCGAGCGGGCTCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTC
CTGCGTCCCTCCCAGCGGCGCGTGAGCGGCACTGATTTGTCCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAA
GGTAAAAGTAACAGAACCATGGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAG
CATGATCAGCAGTTCCATAGTTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCT
CAACCTGTTTTAGCACAGATATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTT
ATCAAACTGAAGCTACAAGGATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCA
TTTGGTATGGGAGGTATCGCCAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCA
ACCCTAGTATCTTCTGTTCCCACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCAT
CCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTT
GATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAA
ACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAAT
CTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCA
CTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCT
GTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAG
CGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCC
CAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAA
AAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAA
CGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAG
AAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACC
ACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCT
CAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCA
CTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGA
TCAAAACTACAGGAGATTGATATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCC
ATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAG
GAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGG
GAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAA
CCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTAT
TACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAA
GAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAG
ACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCT
GGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCT
CTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATG
TACATGGAGGTATCTCCCGAATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAG

>In-frame_ENST00000381318_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=288_stop in transcript=2810
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000381291_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3244nt_BP=2572nt
GAGCGAGGGAGGGAGCGAAGGAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCG
AGGAAGAATCCCGAGCGGGCTCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCG
CGTGAGCGGCACTGATTTGTCCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCAT
GGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAG
TTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGAT
ATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGG
ATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTATCGC
CAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGTTCC
CACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAA
GAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACC
AGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAAC
AGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGA
TGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCC
AGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGA
GGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGG
CAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCA
GGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACG
GCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACG
GAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGA
ATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGA
GAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACT
TATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGC
CTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGA
TATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAA
ACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCT
GGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAA
GGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCA
GGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTT
TGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGC
ACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGA
AGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTA
GGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAAC
AGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGA
ATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCT
CTGCATAGCTAGACCATCTTATTAATAATACTCTGAAAAAAATGATTTCAAGGCATGGAAGTTCTCTGTGATACAACAATAGTATTTCTT
CAAATGCGCCTTATGCTACTTATCTCAGAAACAGGTTTTAAAATGAAGTGCTTTCCAGAGAACCATCATATAAATAAAGATTAATAGAAA

>In-frame_ENST00000381291_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=268_stop in transcript=2790
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000381291_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3093nt_BP=2572nt
GAGCGAGGGAGGGAGCGAAGGAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCG
AGGAAGAATCCCGAGCGGGCTCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCG
CGTGAGCGGCACTGATTTGTCCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCAT
GGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAG
TTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGAT
ATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGG
ATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTATCGC
CAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGTTCC
CACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAA
GAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACC
AGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAAC
AGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGA
TGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCC
AGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGA
GGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGG
CAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCA
GGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACG
GCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACG
GAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGA
ATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGA
GAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACT
TATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGC
CTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGA
TATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAA
ACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCT
GGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAA
GGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCA
GGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTT
TGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGC
ACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGA
AGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTA
GGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAAC
AGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGA
ATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCT

>In-frame_ENST00000381291_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=268_stop in transcript=2790
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399367_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3239nt_BP=2567nt
AGGGAGGGAGCGAAGGAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCGAGGAA
GAATCCCGAGCGGGCTCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCGCGTGA
GCGGCACTGATTTGTCCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCATGGCTC
AGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAGTTTAA
AGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGATATGGG
CACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGGATATC
AGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTATCGCCAGCA
TGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGTTCCCACAG
CAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAAGAGTT
CTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACCAGTGG
CAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAACAGGTC
CCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGATGGAA
AACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCCAGAAT
ACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGAGGAAC
CAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGGCAACC
TGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCAGGAGA
GGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACGGCAGA
GAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACGGAATC
GAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGAATTAG
AAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGAGAGCA
CAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACTTATTC
CAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGCCTTAG
AAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGATATTT
TCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAAACAGA
AAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCTGGAGC
ATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAAGGATG
GCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCAGGCAC
CCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTTTGAAT
CCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGCACAAA
AAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGAAGAAA
TAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTAGGCCT
TTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAACAGAAT
ACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGAATCAT
ACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCTCTGCA
TAGCTAGACCATCTTATTAATAATACTCTGAAAAAAATGATTTCAAGGCATGGAAGTTCTCTGTGATACAACAATAGTATTTCTTCAAAT

>In-frame_ENST00000399367_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=263_stop in transcript=2785
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399367_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3088nt_BP=2567nt
AGGGAGGGAGCGAAGGAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCGAGGAA
GAATCCCGAGCGGGCTCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCGCGTGA
GCGGCACTGATTTGTCCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCATGGCTC
AGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAGTTTAA
AGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGATATGGG
CACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGGATATC
AGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTATCGCCAGCA
TGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGTTCCCACAG
CAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAAGAGTT
CTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACCAGTGG
CAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAACAGGTC
CCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGATGGAA
AACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCCAGAAT
ACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGAGGAAC
CAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGGCAACC
TGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCAGGAGA
GGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACGGCAGA
GAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACGGAATC
GAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGAATTAG
AAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGAGAGCA
CAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACTTATTC
CAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGCCTTAG
AAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGATATTT
TCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAAACAGA
AAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCTGGAGC
ATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAAGGATG
GCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCAGGCAC
CCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTTTGAAT
CCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGCACAAA
AAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGAAGAAA
TAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTAGGCCT
TTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAACAGAAT
ACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGAATCAT
ACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCTCTGCA

>In-frame_ENST00000399367_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=263_stop in transcript=2785
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399352_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3226nt_BP=2554nt
AGGAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCGAGGAAGAATCCCGAGCGG
GCTCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCGCGTGAGCGGCACTGATTT
GTCCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCATGGCTCAGTTTCCAACACC
TTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAGTTTAAAGCCAATATCTGG
ATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGATATGGGCACTAGCTGACAT
GAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGGATATCAGCTACCCTCTGC
ACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTATCGCCAGCATGCCACCGCTTAC
AGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGTTCCCACAGCAGCTGTGCCCCC
CCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAG
ATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGT
TCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAAC
TATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGA
GGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTC
TTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGA
TGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAA
ACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGA
GCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAG
GAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACT
ACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGA
TAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAG
AGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGAT
ACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACT
AGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGATATTTTCAATAATCAGCT
GAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACG
AAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGA
GGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGG
CAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGC
AGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGA
TGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGA
AGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGG
TGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCAT
TTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAA
GCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGAATCATACAAAATTAAATG
TGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCTCTGCATAGCTAGACCATC
TTATTAATAATACTCTGAAAAAAATGATTTCAAGGCATGGAAGTTCTCTGTGATACAACAATAGTATTTCTTCAAATGCGCCTTATGCTA

>In-frame_ENST00000399352_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=250_stop in transcript=2772
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399352_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3075nt_BP=2554nt
AGGAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCGAGGAAGAATCCCGAGCGG
GCTCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCGCGTGAGCGGCACTGATTT
GTCCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCATGGCTCAGTTTCCAACACC
TTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAGTTTAAAGCCAATATCTGG
ATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGATATGGGCACTAGCTGACAT
GAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGGATATCAGCTACCCTCTGC
ACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTATCGCCAGCATGCCACCGCTTAC
AGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGTTCCCACAGCAGCTGTGCCCCC
CCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAG
ATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGT
TCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAAC
TATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGA
GGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTC
TTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGA
TGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAA
ACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGA
GCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAG
GAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACT
ACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGA
TAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAG
AGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGAT
ACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACT
AGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGATATTTTCAATAATCAGCT
GAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACG
AAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGA
GGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGG
CAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGC
AGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGA
TGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGA
AGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGG
TGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCAT
TTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAA
GCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGAATCATACAAAATTAAATG
TGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCTCTGCATAGCTAGACCATC

>In-frame_ENST00000399352_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=250_stop in transcript=2772
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399355_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3224nt_BP=2552nt
GAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCGAGGAAGAATCCCGAGCGGGC
TCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCGCGTGAGCGGCACTGATTTGT
CCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCATGGCTCAGTTTCCAACACCTT
TTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAGTTTAAAGCCAATATCTGGAT
TCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGATATGGGCACTAGCTGACATGA
ATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGGATATCAGCTACCCTCTGCAC
TTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTATCGCCAGCATGCCACCGCTTACAG
CTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGTTCCCACAGCAGCTGTGCCCCCCC
TGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAGAT
CTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGTTC
CTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAACTA
TTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGAGG
AATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTCTT
TTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGATG
AACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAAAC
GAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGAGC
GCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAGGA
GGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACTAC
TAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGATA
AAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAGAG
AGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGATAC
TCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACTAG
CTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGATATTTTCAATAATCAGCTGA
AGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACGAA
AGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGAGG
ACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGGCA
AACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGCAG
AAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGATG
AAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGAAG
ATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGGTG
CGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCATTT
CTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAAGC
CGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGAATCATACAAAATTAAATGTG
AAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCTCTGCATAGCTAGACCATCTT
ATTAATAATACTCTGAAAAAAATGATTTCAAGGCATGGAAGTTCTCTGTGATACAACAATAGTATTTCTTCAAATGCGCCTTATGCTACT

>In-frame_ENST00000399355_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=248_stop in transcript=2770
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399355_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3073nt_BP=2552nt
GAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCGAGGAAGAATCCCGAGCGGGC
TCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCGCGTGAGCGGCACTGATTTGT
CCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCATGGCTCAGTTTCCAACACCTT
TTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAGTTTAAAGCCAATATCTGGAT
TCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGATATGGGCACTAGCTGACATGA
ATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGGATATCAGCTACCCTCTGCAC
TTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTATCGCCAGCATGCCACCGCTTACAG
CTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGTTCCCACAGCAGCTGTGCCCCCCC
TGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAGAT
CTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGTTC
CTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAACTA
TTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGAGG
AATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTCTT
TTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGATG
AACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAAAC
GAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGAGC
GCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAGGA
GGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACTAC
TAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGATA
AAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAGAG
AGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGATAC
TCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACTAG
CTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGATATTTTCAATAATCAGCTGA
AGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACGAA
AGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGAGG
ACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGGCA
AACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGCAG
AAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGATG
AAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGAAG
ATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGGTG
CGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCATTT
CTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAAGC
CGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGAATCATACAAAATTAAATGTG
AAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCTCTGCATAGCTAGACCATCTT

>In-frame_ENST00000399355_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=248_stop in transcript=2770
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399349_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3224nt_BP=2552nt
GAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCGAGGAAGAATCCCGAGCGGGC
TCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCGCGTGAGCGGCACTGATTTGT
CCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCATGGCTCAGTTTCCAACACCTT
TTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAGTTTAAAGCCAATATCTGGAT
TCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGATATGGGCACTAGCTGACATGA
ATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGGATATCAGCTACCCTCTGCAC
TTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTATCGCCAGCATGCCACCGCTTACAG
CTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGTTCCCACAGCAGCTGTGCCCCCCC
TGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAGAT
CTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGTTC
CTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAACTA
TTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGAGG
AATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTCTT
TTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGATG
AACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAAAC
GAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGAGC
GCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAGGA
GGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACTAC
TAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGATA
AAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAGAG
AGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGATAC
TCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACTAG
CTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGATATTTTCAATAATCAGCTGA
AGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACGAA
AGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGAGG
ACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGGCA
AACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGCAG
AAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGATG
AAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGAAG
ATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGGTG
CGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCATTT
CTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAAGC
CGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGAATCATACAAAATTAAATGTG
AAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCTCTGCATAGCTAGACCATCTT
ATTAATAATACTCTGAAAAAAATGATTTCAAGGCATGGAAGTTCTCTGTGATACAACAATAGTATTTCTTCAAATGCGCCTTATGCTACT

>In-frame_ENST00000399349_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=248_stop in transcript=2770
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399349_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=3073nt_BP=2552nt
GAGGTAGAGAAGAGTGGAGGCGCCAGGGGAGGGAGCGTAGCTTGGTTGCTCCGTAGTACGGCGGCTCGCGAGGAAGAATCCCGAGCGGGC
TCCGGGACGGACAGAGAGGCGGGCGGGGATGGTGTGCGGGGCTGCGGCTCCTGCGTCCCTCCCAGCGGCGCGTGAGCGGCACTGATTTGT
CCCTGGGGCGGCAGCGCGGACCCGCCCGGAGATGAGGCGTCGATTAGCAAGGTAAAAGTAACAGAACCATGGCTCAGTTTCCAACACCTT
TTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCATAGTTTAAAGCCAATATCTGGAT
TCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACAGATATGGGCACTAGCTGACATGA
ATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACAAGGATATCAGCTACCCTCTGCAC
TTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTATCGCCAGCATGCCACCGCTTACAG
CTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGTTCCCACAGCAGCTGTGCCCCCCC
TGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAGAT
CTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGTTC
CTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAACTA
TTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGAGG
AATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTCTT
TTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGATG
AACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAAAC
GAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGAGC
GCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAGGA
GGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACTAC
TAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGATA
AAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAGAG
AGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGATAC
TCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACTAG
CTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGATTGATATTTTCAATAATCAGCTGA
AGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACGAA
AGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGAGG
ACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGGCA
AACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGCAG
AAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGATG
AAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGAAG
ATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGGTG
CGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCATTT
CTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAAGC
CGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCCCGAATCATACAAAATTAAATGTG
AAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTTGCTCTGCATAGCTAGACCATCTT

>In-frame_ENST00000399349_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=248_stop in transcript=2770
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399338_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=2995nt_BP=2323nt
AGGTAAAAGTAACAGAACCATGGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAA
GCATGATCAGCAGTTCCATAGTTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACC
TCAACCTGTTTTAGCACAGATATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACT
TATCAAACTGAAGCTACAAGGATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGC
ATTTGGTATGGGAGGTATCGCCAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCC
AACCCTAGTATCTTCTGTTCCCACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCA
TCCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATT
TGATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAA
AACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAA
TCTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACC
ACTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATC
TGTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAA
GCGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGC
CCAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGA
AAAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCA
ACGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAA
GAAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGAC
CACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATC
TCAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTC
ACTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAG
ATCAAAACTACAGGAGATTGATATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTC
CATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCA
GGAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAG
GGAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGA
ACCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTA
TTACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGA
AGAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGA
GACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCC
TGGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTC
TCTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGAT
GTACATGGAGGTATCTCCCGAATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAA
GATTTTTTTTTCTTTTTTGCTCTGCATAGCTAGACCATCTTATTAATAATACTCTGAAAAAAATGATTTCAAGGCATGGAAGTTCTCTGT
GATACAACAATAGTATTTCTTCAAATGCGCCTTATGCTACTTATCTCAGAAACAGGTTTTAAAATGAAGTGCTTTCCAGAGAACCATCAT

>In-frame_ENST00000399338_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=19_stop in transcript=2541
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399338_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=2844nt_BP=2323nt
AGGTAAAAGTAACAGAACCATGGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAA
GCATGATCAGCAGTTCCATAGTTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACC
TCAACCTGTTTTAGCACAGATATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACT
TATCAAACTGAAGCTACAAGGATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGC
ATTTGGTATGGGAGGTATCGCCAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCC
AACCCTAGTATCTTCTGTTCCCACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCA
TCCTGCAGCCACATTGCCAAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATT
TGATGTGGCCAGTGTCCCACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAA
AACTATGAGTGGACACTTAACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAA
TCTTTCTGACATTGATCAAGATGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACC
ACTGCCACCTGTCCTGCCTCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATC
TGTAGATCAGAGGCTACCAGAGGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAA
GCGGGAGAACTTTGAACGTGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGC
CCAGCTGGAGCGGGCGGAGCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGA
AAAGCAGCGGGAGCTAGAACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCA
ACGACAACTTGAGTGGGAACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAA
GAAAAAGACTTTGGAATTTGAATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGAC
CACCCAAAGGCAAGAAATTGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATC
TCAGCAAATGCTTGGAAGACTTATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTC
ACTTGTTACACTTAAAAGAGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAG
ATCAAAACTACAGGAGATTGATATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTC
CATGGAGGCTGAACGACTGAAACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCA
GGAAAGGGACAAGCAGTGGCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAG
GGAGGAGAGTGTCAAAAAGAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGA
ACCAGCTAAGCCAGCTGTCCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTA
TTACCGGGCACTGTACCCCTTTGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGA
AGAAGGTGGAGAAACTGAGGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGA
GACAGCCACAGAAGAGACGGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCC
TGGAGAAGACGAAGATTCCTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTC
TCTCCACAAACCAAACTCAACAGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGAT
GTACATGGAGGTATCTCCCGAATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAA

>In-frame_ENST00000399338_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=19_stop in transcript=2541
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000379960_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=2977nt_BP=2305nt
CATGGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCA
TAGTTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACA
GATATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACA
AGGATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTAT
CGCCAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGT
TCCCACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCC
AAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCC
ACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTT
AACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCA
AGATGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCC
TCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACC
AGAGGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACG
TGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGA
GCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGA
ACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGA
ACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATT
TGAATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAAT
TGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAG
ACTTATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAG
AGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGAT
TGATATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACT
GAAACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTG
GCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAA
GAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGT
CCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCC
CTTTGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGA
GGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGAC
GGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTC
CTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTC
AACAGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCC
CGAATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTT
GCTCTGCATAGCTAGACCATCTTATTAATAATACTCTGAAAAAAATGATTTCAAGGCATGGAAGTTCTCTGTGATACAACAATAGTATTT
CTTCAAATGCGCCTTATGCTACTTATCTCAGAAACAGGTTTTAAAATGAAGTGCTTTCCAGAGAACCATCATATAAATAAAGATTAATAG

>In-frame_ENST00000379960_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=1_stop in transcript=2523
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000379960_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=2826nt_BP=2305nt
CATGGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCA
TAGTTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACA
GATATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACA
AGGATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTAT
CGCCAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGT
TCCCACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCC
AAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCC
ACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTT
AACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCA
AGATGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCC
TCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACC
AGAGGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACG
TGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGA
GCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGA
ACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGA
ACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATT
TGAATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAAT
TGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAG
ACTTATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAG
AGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGAT
TGATATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACT
GAAACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTG
GCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAA
GAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGT
CCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCC
CTTTGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGA
GGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGAC
GGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTC
CTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTC
AACAGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCC
CGAATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTT

>In-frame_ENST00000379960_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=1_stop in transcript=2523
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000437442_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=2977nt_BP=2305nt
CATGGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCA
TAGTTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACA
GATATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACA
AGGATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTAT
CGCCAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGT
TCCCACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCC
AAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCC
ACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTT
AACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCA
AGATGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCC
TCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACC
AGAGGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACG
TGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGA
GCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGA
ACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGA
ACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATT
TGAATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAAT
TGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAG
ACTTATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAG
AGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGAT
TGATATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACT
GAAACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTG
GCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAA
GAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGT
CCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCC
CTTTGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGA
GGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGAC
GGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTC
CTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTC
AACAGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCC
CGAATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTT
GCTCTGCATAGCTAGACCATCTTATTAATAATACTCTGAAAAAAATGATTTCAAGGCATGGAAGTTCTCTGTGATACAACAATAGTATTT
CTTCAAATGCGCCTTATGCTACTTATCTCAGAAACAGGTTTTAAAATGAAGTGCTTTCCAGAGAACCATCATATAAATAAAGATTAATAG

>In-frame_ENST00000437442_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=1_stop in transcript=2523
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000437442_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=2826nt_BP=2305nt
CATGGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCA
TAGTTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACA
GATATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACA
AGGATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTAT
CGCCAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGT
TCCCACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCC
AAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCC
ACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTT
AACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCA
AGATGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCC
TCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACC
AGAGGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACG
TGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGA
GCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGA
ACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGA
ACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATT
TGAATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAAT
TGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAG
ACTTATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAG
AGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGAT
TGATATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACT
GAAACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTG
GCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAA
GAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGT
CCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCC
CTTTGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGA
GGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGAC
GGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTC
CTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTC
AACAGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCC
CGAATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTT

>In-frame_ENST00000437442_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=1_stop in transcript=2523
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399326_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=2977nt_BP=2305nt
CATGGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCA
TAGTTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACA
GATATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACA
AGGATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTAT
CGCCAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGT
TCCCACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCC
AAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCC
ACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTT
AACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCA
AGATGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCC
TCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACC
AGAGGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACG
TGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGA
GCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGA
ACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGA
ACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATT
TGAATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAAT
TGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAG
ACTTATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAG
AGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGAT
TGATATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACT
GAAACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTG
GCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAA
GAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGT
CCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCC
CTTTGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGA
GGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGAC
GGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTC
CTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTC
AACAGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCC
CGAATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTT
GCTCTGCATAGCTAGACCATCTTATTAATAATACTCTGAAAAAAATGATTTCAAGGCATGGAAGTTCTCTGTGATACAACAATAGTATTT
CTTCAAATGCGCCTTATGCTACTTATCTCAGAAACAGGTTTTAAAATGAAGTGCTTTCCAGAGAACCATCATATAAATAAAGATTAATAG

>In-frame_ENST00000399326_ENST00000380637_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=1_stop in transcript=2523
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------
>In-frame_ENST00000399326_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(transcript)=2826nt_BP=2305nt
CATGGCTCAGTTTCCAACACCTTTTGGTGGCAGCCTGGATATCTGGGCCATAACTGTAGAGGAAAGAGCGAAGCATGATCAGCAGTTCCA
TAGTTTAAAGCCAATATCTGGATTCATTACTGGTGATCAAGCTAGAAACTTTTTTTTTCAATCTGGGTTACCTCAACCTGTTTTAGCACA
GATATGGGCACTAGCTGACATGAATAATGATGGAAGAATGGATCAAGTGGAGTTTTCCATAGCTATGAAACTTATCAAACTGAAGCTACA
AGGATATCAGCTACCCTCTGCACTTCCCCCTGTCATGAAACAGCAACCAGTTGCTATTTCTAGCGCACCAGCATTTGGTATGGGAGGTAT
CGCCAGCATGCCACCGCTTACAGCTGTTGCTCCAGTGCCAATGGGATCCATTCCAGTTGTTGGAATGTCTCCAACCCTAGTATCTTCTGT
TCCCACAGCAGCTGTGCCCCCCCTGGCTAACGGGGCTCCCCCTGTTATACAACCTCTGCCTGCATTTGCTCATCCTGCAGCCACATTGCC
AAAGAGTTCTTCCTTTAGTAGATCTGGTCCAGGGTCACAACTAAACACTAAATTACAAAAGGCACAGTCATTTGATGTGGCCAGTGTCCC
ACCAGTGGCAGAGTGGGCTGTTCCTCAGTCATCAAGACTGAAATACAGGCAATTATTCAATAGTCATGACAAAACTATGAGTGGACACTT
AACAGGTCCCCAAGCAAGAACTATTCTTATGCAGTCAAGTTTACCACAGGCTCAGCTGGCTTCAATATGGAATCTTTCTGACATTGATCA
AGATGGAAAACTTACAGCAGAGGAATTTATCCTGGCAATGCACCTCATTGATGTAGCTATGTCTGGCCAACCACTGCCACCTGTCCTGCC
TCCAGAATACATTCCACCTTCTTTTAGAAGAGTTCGATCTGGCAGTGGTATATCTGTCATAAGCTCAACATCTGTAGATCAGAGGCTACC
AGAGGAACCAGTTTTAGAAGATGAACAACAACAATTAGAAAAGAAATTACCTGTAACGTTTGAAGATAAGAAGCGGGAGAACTTTGAACG
TGGCAACCTGGAACTGGAGAAACGAAGGCAAGCTCTCCTGGAACAGCAGCGCAAGGAGCAGGAGCGCCTGGCCCAGCTGGAGCGGGCGGA
GCAGGAGAGGAAGGAGCGTGAGCGCCAGGAGCAAGAGCGCAAAAGACAACTGGAACTGGAGAAGCAACTGGAAAAGCAGCGGGAGCTAGA
ACGGCAGAGAGAGGAGGAGAGGAGGAAAGAAATTGAGAGGCGAGAGGCTGCAAAACGGGAACTTGAAAGGCAACGACAACTTGAGTGGGA
ACGGAATCGAAGGCAAGAACTACTAAATCAAAGAAACAAAGAACAAGAGGACATAGTTGTACTGAAAGCAAAGAAAAAGACTTTGGAATT
TGAATTAGAAGCTCTAAATGATAAAAAGCATCAACTAGAAGGGAAACTTCAAGATATCAGATGTCGATTGACCACCCAAAGGCAAGAAAT
TGAGAGCACAAACAAATCTAGAGAGTTGAGAATTGCCGAAATCACCCATCTACAGCAACAATTACAGGAATCTCAGCAAATGCTTGGAAG
ACTTATTCCAGAAAAACAGATACTCAATGACCAATTAAAACAAGTTCAGCAGAACAGTTTGCACAGAGATTCACTTGTTACACTTAAAAG
AGCCTTAGAAGCAAAAGAACTAGCTCGGCAGCACCTACGAGACCAACTGGATGAAGTGGAGAAAGAAACTAGATCAAAACTACAGGAGAT
TGATATTTTCAATAATCAGCTGAAGGAACTAAGAGAAATACACAATAAGCAACAACTCCAGAAGCAAAAGTCCATGGAGGCTGAACGACT
GAAACAGAAAGAACAAGAACGAAAGATCATAGAATTAGAAAAACAAAAAGAAGAAGCCCAAAGACGAGCTCAGGAAAGGGACAAGCAGTG
GCTGGAGCATGTGCAGCAGGAGGACGAGCATCAGAGACCAAGAAAACTCCACGAAGAGGAAAAACTGAAAAGGGAGGAGAGTGTCAAAAA
GAAGGATGGCGAGGAAAAAGGCAAACAGGAAGCACAAGACAAGCTGGGTCGGCTTTTCCATCAACACCAAGAACCAGCTAAGCCAGCTGT
CCAGGCACCCTGGTCCACTGCAGAAAAAGGTCCACTTACCATTTCTGCACAGGAAAATGTAAAAGTGGTGTATTACCGGGCACTGTACCC
CTTTGAATCCAGAAGCCATGATGAAATCACTATCCAGCCAGGAGACATAGTCATGGGATCAGAGAAGGCTGAAGAAGGTGGAGAAACTGA
GGCACAAAAAGAGGGCAGTGAAGATGTGGGCAACCTCCCTGAAGCCCAGGAGAAGAATGAAGAAGAAGGAGAGACAGCCACAGAAGAGAC
GGAAGAAATAGCCATGGAGGGTGCGGAAGGGGAAGCCGAGGAGGAGGAAGAAACTGCAGAAGGAGAAGAGCCTGGAGAAGACGAAGATTC
CTAGGCCTTTTCATGCTTCATTTCTTCCACTTCTCCAGAAAATGGAAGCTATGAAGCAACATTTCAAATGTCTCTCCACAAACCAAACTC
AACAGAATACTTTGGCTTGAAGCCGGCACACCCAGGGTTACTGAGGACTTATGCTGCCTGACCTGGTTAGATGTACATGGAGGTATCTCC
CGAATCATACAAAATTAAATGTGAAGACCGTTTATGCATACCTTCATGTGCCTGACAGTCTTGGCTTTTGAAGATTTTTTTTTCTTTTTT

>In-frame_ENST00000399326_ENST00000380634_TCGA-BR-8365-01A_ITSN1_chr21_35172233_+_SH3BGR_chr21_40871749_length(amino acids)=840AA_start in transcript=1_stop in transcript=2523
MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQ
GYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLP
KSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ
DGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFER
GNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWE
RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGR
LIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERL
KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAV
QAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEET

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ITSN1-SH3BGR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ITSN1-SH3BGR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ITSN1-SH3BGR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneITSN1C0033578Prostatic Neoplasms1CTD_human
HgeneITSN1C0376358Malignant neoplasm of prostate1CTD_human