|
||||||
|
 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:KDM4B-SBNO2 (FusionGDB2 ID:41624) |
Fusion Gene Summary for KDM4B-SBNO2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KDM4B-SBNO2 | Fusion gene ID: 41624 | Hgene | Tgene | Gene symbol | KDM4B | SBNO2 | Gene ID | 23030 | 22904 |
| Gene name | lysine demethylase 4B | strawberry notch homolog 2 | |
| Synonyms | JMJD2B|TDRD14B | KIAA0963|SNO|STNO | |
| Cytomap | 19p13.3 | 19p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | lysine-specific demethylase 4BjmjC domain-containing histone demethylation protein 3Bjumonji domain containing 2Bjumonji domain-containing protein 2Blysine (K)-specific demethylase 4Btudor domain containing 14B | protein strawberry notch homolog 2 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | O94953 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000159111, ENST00000381759, ENST00000536461, ENST00000592175, | ENST00000361757, ENST00000587024, ENST00000438103, | |
| Fusion gene scores | * DoF score | 30 X 16 X 14=6720 | 8 X 5 X 6=240 |
| # samples | 38 | 10 | |
| ** MAII score | log2(38/6720*10)=-4.14438990933518 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/240*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: KDM4B [Title/Abstract] AND SBNO2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | KDM4B(5082515)-SBNO2(1127764), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | KDM4B | GO:0033169 | histone H3-K9 demethylation | 21914792 |
| Hgene | KDM4B | GO:0070544 | histone H3-K36 demethylation | 21914792 |
| Tgene | SBNO2 | GO:0071354 | cellular response to interleukin-6 | 25903009 |
| Fusion gene breakpoints across KDM4B (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across SBNO2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LGG | TCGA-WY-A85E-01A | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
Top |
Fusion Gene ORF analysis for KDM4B-SBNO2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000159111 | ENST00000361757 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| In-frame | ENST00000159111 | ENST00000587024 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| In-frame | ENST00000159111 | ENST00000438103 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| In-frame | ENST00000381759 | ENST00000361757 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| In-frame | ENST00000381759 | ENST00000587024 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| In-frame | ENST00000381759 | ENST00000438103 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| In-frame | ENST00000536461 | ENST00000361757 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| In-frame | ENST00000536461 | ENST00000587024 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| In-frame | ENST00000536461 | ENST00000438103 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| intron-3CDS | ENST00000592175 | ENST00000361757 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| intron-3CDS | ENST00000592175 | ENST00000587024 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| intron-3CDS | ENST00000592175 | ENST00000438103 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000159111 | KDM4B | chr19 | 5082515 | - | ENST00000361757 | SBNO2 | chr19 | 1127764 | - | 5541 | 1136 | 218 | 4957 | 1579 |
| ENST00000159111 | KDM4B | chr19 | 5082515 | - | ENST00000587024 | SBNO2 | chr19 | 1127764 | - | 5507 | 1136 | 218 | 4927 | 1569 |
| ENST00000159111 | KDM4B | chr19 | 5082515 | - | ENST00000438103 | SBNO2 | chr19 | 1127764 | - | 5536 | 1136 | 218 | 4957 | 1579 |
| ENST00000381759 | KDM4B | chr19 | 5082515 | - | ENST00000361757 | SBNO2 | chr19 | 1127764 | - | 5530 | 1125 | 207 | 4946 | 1579 |
| ENST00000381759 | KDM4B | chr19 | 5082515 | - | ENST00000587024 | SBNO2 | chr19 | 1127764 | - | 5496 | 1125 | 207 | 4916 | 1569 |
| ENST00000381759 | KDM4B | chr19 | 5082515 | - | ENST00000438103 | SBNO2 | chr19 | 1127764 | - | 5525 | 1125 | 207 | 4946 | 1579 |
| ENST00000536461 | KDM4B | chr19 | 5082515 | - | ENST00000361757 | SBNO2 | chr19 | 1127764 | - | 5363 | 958 | 40 | 4779 | 1579 |
| ENST00000536461 | KDM4B | chr19 | 5082515 | - | ENST00000587024 | SBNO2 | chr19 | 1127764 | - | 5329 | 958 | 40 | 4749 | 1569 |
| ENST00000536461 | KDM4B | chr19 | 5082515 | - | ENST00000438103 | SBNO2 | chr19 | 1127764 | - | 5358 | 958 | 40 | 4779 | 1579 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000159111 | ENST00000361757 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - | 0.002687097 | 0.99731284 |
| ENST00000159111 | ENST00000587024 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - | 0.003132243 | 0.9968677 |
| ENST00000159111 | ENST00000438103 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - | 0.002733152 | 0.9972669 |
| ENST00000381759 | ENST00000361757 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - | 0.00261162 | 0.9973884 |
| ENST00000381759 | ENST00000587024 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - | 0.00304463 | 0.9969554 |
| ENST00000381759 | ENST00000438103 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - | 0.002655954 | 0.9973441 |
| ENST00000536461 | ENST00000361757 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - | 0.002230469 | 0.9977696 |
| ENST00000536461 | ENST00000587024 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - | 0.002611101 | 0.9973889 |
| ENST00000536461 | ENST00000438103 | KDM4B | chr19 | 5082515 | - | SBNO2 | chr19 | 1127764 | - | 0.002266631 | 0.99773335 |
Top |
Fusion Genomic Features for KDM4B-SBNO2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
Top |
Fusion Protein Features for KDM4B-SBNO2 |
| Go to FGviewer for the breakpoints of chr19:5082515-chr19:1127764 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KDM4B | . |
| FUNCTION: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. {ECO:0000269|PubMed:16603238, ECO:0000269|PubMed:28262558}. | FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000159111 | - | 9 | 23 | 146_309 | 306.0 | 1097.0 | Domain | JmjC |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000159111 | - | 9 | 23 | 15_57 | 306.0 | 1097.0 | Domain | JmjN |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000381759 | - | 9 | 12 | 146_309 | 306.0 | 449.0 | Domain | JmjC |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000381759 | - | 9 | 12 | 15_57 | 306.0 | 449.0 | Domain | JmjN |
| Tgene | SBNO2 | chr19:5082515 | chr19:1127764 | ENST00000361757 | 3 | 32 | 1234_1294 | 93.0 | 1367.0 | Compositional bias | Note=Pro-rich | |
| Tgene | SBNO2 | chr19:5082515 | chr19:1127764 | ENST00000361757 | 3 | 32 | 183_195 | 93.0 | 1367.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | SBNO2 | chr19:5082515 | chr19:1127764 | ENST00000438103 | 0 | 29 | 1234_1294 | 36.0 | 1310.0 | Compositional bias | Note=Pro-rich | |
| Tgene | SBNO2 | chr19:5082515 | chr19:1127764 | ENST00000438103 | 0 | 29 | 183_195 | 36.0 | 1310.0 | Compositional bias | Note=Poly-Glu |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000159111 | - | 9 | 23 | 463_535 | 306.0 | 1097.0 | Compositional bias | Note=Pro-rich |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000381759 | - | 9 | 12 | 463_535 | 306.0 | 449.0 | Compositional bias | Note=Pro-rich |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000159111 | - | 9 | 23 | 917_974 | 306.0 | 1097.0 | Domain | Note=Tudor 1 |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000159111 | - | 9 | 23 | 975_1031 | 306.0 | 1097.0 | Domain | Note=Tudor 2 |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000381759 | - | 9 | 12 | 917_974 | 306.0 | 449.0 | Domain | Note=Tudor 1 |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000381759 | - | 9 | 12 | 975_1031 | 306.0 | 449.0 | Domain | Note=Tudor 2 |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000159111 | - | 9 | 23 | 731_789 | 306.0 | 1097.0 | Zinc finger | Note=PHD-type 1 |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000159111 | - | 9 | 23 | 794_827 | 306.0 | 1097.0 | Zinc finger | C2HC pre-PHD-type |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000159111 | - | 9 | 23 | 850_907 | 306.0 | 1097.0 | Zinc finger | PHD-type 2 |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000381759 | - | 9 | 12 | 731_789 | 306.0 | 449.0 | Zinc finger | Note=PHD-type 1 |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000381759 | - | 9 | 12 | 794_827 | 306.0 | 449.0 | Zinc finger | C2HC pre-PHD-type |
| Hgene | KDM4B | chr19:5082515 | chr19:1127764 | ENST00000381759 | - | 9 | 12 | 850_907 | 306.0 | 449.0 | Zinc finger | PHD-type 2 |
Top |
Fusion Gene Sequence for KDM4B-SBNO2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000159111_ENST00000361757_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(transcript)=5541nt_BP=1136nt GTCGCCAGCAACCGAGCGGGGCCCGGCCCGAGCGGGGCCTGGGGGTGCGACGCCGAGGGCGGGGGAGAGCGCGCCGCTGCTCCCGGACCG GGCCGCGCACGCCGCCTCAGGAACCATCACTGTTGCTGGAGGCACCTGACAAATCCTAGCGAATTTTTGGAGCATCTCCACCCAGGAACC TCGCCATCCAGAAGTGTGCTTCCCGCACAGCTGCAGCCATGGGGTCTGAGGACCACGGCGCCCAGAACCCCAGCTGTAAAATCATGACGT TTCGCCCAACCATGGAAGAATTTAAAGACTTCAACAAATACGTGGCCTACATAGAGTCGCAGGGAGCCCACCGGGCGGGCCTGGCCAAGA TCATCCCCCCGAAGGAGTGGAAGCCGCGGCAGACGTATGATGACATCGACGACGTGGTGATCCCGGCGCCCATCCAGCAGGTGGTGACGG GCCAGTCGGGCCTCTTCACGCAGTACAATATCCAGAAGAAGGCCATGACAGTGGGCGAGTACCGCCGCCTGGCCAACAGCGAGAAGTACT GTACCCCGCGGCACCAGGACTTTGATGACCTTGAACGCAAATACTGGAAGAACCTCACCTTTGTCTCCCCGATCTACGGGGCTGACATCA GCGGCTCTTTGTATGATGACGACGTGGCCCAGTGGAACATCGGGAGCCTCCGGACCATCCTGGACATGGTGGAGCGCGAGTGCGGCACCA TCATCGAGGGCGTGAACACGCCCTACCTGTACTTCGGCATGTGGAAGACCACCTTCGCCTGGCACACCGAGGACATGGACCTGTACAGCA TCAACTACCTGCACTTTGGGGAGCCTAAGTCCTGGTACGCCATCCCACCAGAGCACGGCAAGCGCCTGGAGCGGCTGGCCATCGGCTTCT TCCCCGGGAGCTCGCAGGGCTGCGACGCCTTCCTGCGGCATAAGATGACCCTCATCTCGCCCATCATCCTGAAGAAGTACGGGATCCCCT TCAGCCGGATCACGCAGGAGGCCGGGGAATTCATGATCACATTTCCCTACGGCTACCACGCCGGCTTCAATCACGGGTTCAACTGCGCAG AATCTACCAACTTCGCCACCCTGCGGTGGATTGACTACGGCAAAGTGGCCACTCAGGACTCCTCCTATTTTGAGGACTTCTCCAACATCT CCATCTTCTCCTCGTCCGTGGACTCCCTGTCGGACATCGTGGACACGCCCGACTTCCTGCCGGCTGACAGCCTCAACCAGGTGTCCACCA TCTGGGACGATAACCCTGCCCCCTCCACCCACGATAAGCTGTTCCAGCTCAGCAGGCCGTTTGCAGGCTTCGAGGACTTTCTGCCCTCCC ACAGCACCCCGCTTCTCGTCAGCTACCAGGAGCAGAGTGTGCAGAGCCAGCCAGAGGAGGAGGACGAGGCTGAGGAGGAGGAGGCGGAGG AGCTGGGGCACACAGAGACCTACGCCGACTACGTGCCGTCCAAGTCCAAGATCGGGAAGCAGCACCCAGACCGCGTGGTGGAGACCAGCA CACTGTCCAGCGTCCCACCCCCAGACATCACCTACACCCTGGCCCTGCCCTCGGACAGCGGGGCCCTGTCTGCCCTGCAGCTAGAGGCCA TCACCTACGCCTGCCAGCAACACGAGGTCCTGCTCCCCAGCGGGCAGCGCGCGGGCTTTCTCATCGGCGATGGGGCCGGCGTGGGCAAAG GCCGGACGGTGGCCGGAGTCATCCTGGAGAACCACCTGCGCGGCCGGAAGAAAGCATTGTGGTTCAGCGTCTCCAACGACCTCAAGTACG ATGCGGAGCGCGACCTGCGGGACATCGAAGCCACGGGCATCGCGGTGCACGCGCTCAGCAAGATCAAGTACGGTGACACCACTACCTCAG AGGGCGTCCTCTTCGCCACCTACTCCGCCCTGATTGGGGAGAGCCAGGCCGGCGGCCAGCACCGCACTCGCCTCCGGCAGATCCTGGACT GGTGTGGGGAGGCCTTCGAGGGCGTCATCGTGTTCGACGAGTGTCACAAAGCCAAGAATGCCGGCTCCACCAAGATGGGCAAGGCTGTGC TAGACCTGCAGAACAAGCTGCCCCTGGCCCGCGTGGTCTACGCCAGCGCCACAGGTGCCTCTGAGCCTCGGAACATGATCTACATGAGCC GCTTGGGTATCTGGGGCGAGGGCACACCCTTCCGGAACTTTGAGGAGTTCCTGCACGCCATCGAGAAGAGGGGCGTTGGCGCCATGGAGA TCGTGGCCATGGACATGAAGGTCAGCGGCATGTACATCGCACGCCAGCTCAGCTTCTCCGGCGTCACCTTCCGCATCGAGGAGATCCCGC TGGCCCCAGCCTTCGAGTGCGTCTACAACCGCGCGGCCCTGCTGTGGGCCGAGGCCCTGAACGTGTTCCAGCAGGCGGCCGACTGGATCG GCCTGGAGTCGCGCAAGTCCCTGTGGGGCCAGTTCTGGTCGGCACACCAGCGCTTCTTCAAGTATCTGTGCATCGCAGCCAAGGTGCGCC GGCTGGTGGAGCTGGCCCGAGAGGAGCTGGCGCGAGACAAGTGCGTGGTCATCGGGCTGCAGTCCACGGGCGAGGCGCGCACGCGGGAGG TGCTGGGGGAGAACGATGGGCACCTCAACTGCTTCGTCTCGGCCGCTGAAGGCGTGTTCCTGTCGCTAATTCAGAAGCACTTTCCGTCCA CCAAGAGAAAGCGGGACAGAGGAGCGGGCAGCAAGCGGAAACGGCGACCTCGGGGACGCGGGGCCAAAGCCCCCCGGCTGGCGTGCGAGA CAGCGGGCGTCATCCGCATCAGTGACGACAGCAGCACGGAGTCGGACCCTGGCCTGGACAGCGACTTCAACTCCTCCCCCGAGTCCCTGG TGGATGACGACGTTGTCATCGTTGATGCAGTCGGGCTCCCCAGTGACGACCGGGGACCCCTGTGCCTCCTGCAGAGAGACCCGCATGGCC CCGGGGTCCTGGAGCGGGTGGAGCGGCTGAAGCAGGATCTGCTGGACAAAGTGCGGCGGCTGGGCCGGGAACTGCCAGTCAACACCCTGG ACGAGCTCATCGACCAGCTGGGCGGCCCCCAGCGGGTGGCGGAGATGACCGGCAGGAAAGGCCGCGTGGTGTCCAGGCCCGACGGGACGG TGGCCTTCGAGTCGCGGGCAGAGCAGGGTCTGTCCATCGACCACGTGAACCTCAGGGAGAAGCAGCGCTTCATGAGCGGCGAGAAGCTCG TGGCCATCATCTCGGAGGCCTCCAGCTCGGGTGTCTCCCTCCAAGCCGACCGCCGTGTCCAGAACCAGCGGCGCCGCGTGCACATGACCT TGGAGCTGCCGTGGAGCGCCGACCGCGCCATCCAGCAGTTCGGCCGCACCCACCGGTCCAACCAGGTCTCCGCGCCAGAGTATGTCTTCC TCATCTCGGAGCTGGCCGGGGAGCGCCGGTTCGCCTCCATCGTGGCCAAGCGCCTGGAGAGTCTGGGGGCCCTGACCCACGGAGACCGCC GCGCCACGGAGTCCCGTGACCTCAGCAAGTACAACTTTGAGAACAAGTATGGCACCCGGGCCCTGCACTGTGTCCTCACCACCATCCTGA GCCAGACTGAGAACAAAGTGCCTGTGCCCCAGGGATACCCTGGAGGGGTCCCCACCTTCTTCCGGGACATGAAGCAGGGCCTGCTGTCTG TGGGCATTGGTGGCCGGGAGTCCCGGAATGGCTGCCTGGACGTGGAGAAGGACTGTTCCATCACCAAGTTCCTGAACCGCATCCTGGGGC TGGAGGTGCACAAGCAGAACGCCCTGTTCCAGTACTTCTCAGACACCTTCGACCACCTCATCGAGATGGACAAGCGGGAGGGCAAATACG ACATGGGCATCCTGGACCTTGCTCCCGGTATCGAGGAGATCTACGAGGAGAGCCAGCAGGTGTTCCTGGCTCCCGGGCACCCGCAGGACG GGCAGGTGGTCTTCTACAAGATCAGCGTGGACCGCGGCCTGAAGTGGGAGGACGCCTTTGCCAAGTCGCTGGCGCTGACGGGCCCCTATG ACGGCTTCTACCTCTCCTACAAGGTCCGCGGTAACAAGCCCAGCTGCCTGCTGGCGGAGCAGAACCGCGGCCAGTTCTTCACGGTGTACA AGCCCAACATCGGCCGGCAGAGCCAGCTGGAGGCCCTGGACAGCCTCCGCCGCAAGTTCCACCGGGTCACCGCGGAGGAGGCCAAGGAGC CCTGGGAGAGTGGCTACGCTTTGTCGCTGACGCACTGCAGCCACAGCGCCTGGAACCGGCACTGCCGGCTGGCGCAGGAGGGTAAGGACT GCCTGCAGGGGCTGCGGCTGCGGCACCACTACATGCTGTGCGGCGCGCTGCTGCGCGTGTGGGGCCGCATCGCCGCCGTCATGGCCGACG TCAGCAGCAGCAGCTACCTGCAGATCGTGCGGCTGAAGACCAAGGACAGGAAGAAGCAAGTGGGCATCAAGATCCCCGAGGGCTGCGTGC GCCGGGTGCTGCAGGAGCTGCGGCTGATGGATGCGGACGTGAAGCGCAGGCAGGCGCCCGCCCTGGGCTGCCCCGCCCCGCCCGCCCCGC GCCCGCTGGCGCTGCCTTGCGGCCCCGGAGAGGTGCTGGACCTCACCTACAGCCCCCCGGCCGAGGCCTTCCCGCCGCCCCCGCACTTCT CTTTCCCGGCGCCGCTGTCCCTGGACGCCGGCCCCGGCGTCGTGCCGCTGGGCACCCCCGACGCCCAGGCCGACCCTGCGGCCCTCGCGC ACCAGGGCTGCGACATCAACTTCAAGGAGGTGCTGGAGGACATGCTGCGCTCGCTGCACGCGGGGCCGCCCTCCGAGGGCGCGCTGGGGG AGGGCGCGGGGGCGGGGGGCGCGGCGGGCGGTGGTCCCGAGCGGCAGAGCGTGATCCAGTTCAGCCCACCCTTCCCCGGCGCCCAGGCTC CTCTCTGACACGCCTTTAGGCGAAACATGCCCCAAGACACAGGGACCGTTTCTCCCCTAGGAGCAGCGGTGGGGAGCAGGGCCAAGGTCC CCTGACCACTGCTCAGAGGAGCCCTAGGCCCTGGCCGCAGTGCCTTCAGCGCCCGACCCGGGCCCCCACCTGGTCAGCCCTGGCGGGGCC CACTCAGGACAGCTGGGGGCCGGGGCGTGGCAGGGCCCTCTCTGTGCCTCTCCTCCCAAGTAGGAAGGGGCTCCGGGTGGCTGCTCTGGG ACTGGGCACCCACAAGGGCTCAGTGGGCCCAAACCCTTGAAATCCGTGAAACCGGGTGGTCCCAAGAGCTAGAAACTCAGGAAACCCCAG GTGCTCAGGGCCCCGCGTCTCGGGGGCTCCGTGGGGCAGACCCCTGCTAATATATGCAATTCTCCCTCCCCCAGCCCTTCCCTGACCCCT AAGTTATTGCCCGCTCACCTCTCCCAGGCCCCAGGCCGCGGAGCTGGCAGGGTGGCGCCTGCGGTTTCTATGTATTTATAGCAAGTTCTG >In-frame_ENST00000159111_ENST00000361757_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(amino acids)=1579AA_start in transcript=218_stop in transcript=4957 MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQK KAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFG MWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMI TFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDK LFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYT LALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATG IAVHALSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVV YASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAA LLWAEALNVFQQAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFV SAAEGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGL PSDDRGPLCLLQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSI DHVNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFAS IVAKRLESLGALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCL DVEKDCSITKFLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRG LKWEDAFAKSLALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHC SHSAWNRHCRLAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDAD VKRRQAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLE -------------------------------------------------------------- >In-frame_ENST00000159111_ENST00000587024_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(transcript)=5507nt_BP=1136nt GTCGCCAGCAACCGAGCGGGGCCCGGCCCGAGCGGGGCCTGGGGGTGCGACGCCGAGGGCGGGGGAGAGCGCGCCGCTGCTCCCGGACCG GGCCGCGCACGCCGCCTCAGGAACCATCACTGTTGCTGGAGGCACCTGACAAATCCTAGCGAATTTTTGGAGCATCTCCACCCAGGAACC TCGCCATCCAGAAGTGTGCTTCCCGCACAGCTGCAGCCATGGGGTCTGAGGACCACGGCGCCCAGAACCCCAGCTGTAAAATCATGACGT TTCGCCCAACCATGGAAGAATTTAAAGACTTCAACAAATACGTGGCCTACATAGAGTCGCAGGGAGCCCACCGGGCGGGCCTGGCCAAGA TCATCCCCCCGAAGGAGTGGAAGCCGCGGCAGACGTATGATGACATCGACGACGTGGTGATCCCGGCGCCCATCCAGCAGGTGGTGACGG GCCAGTCGGGCCTCTTCACGCAGTACAATATCCAGAAGAAGGCCATGACAGTGGGCGAGTACCGCCGCCTGGCCAACAGCGAGAAGTACT GTACCCCGCGGCACCAGGACTTTGATGACCTTGAACGCAAATACTGGAAGAACCTCACCTTTGTCTCCCCGATCTACGGGGCTGACATCA GCGGCTCTTTGTATGATGACGACGTGGCCCAGTGGAACATCGGGAGCCTCCGGACCATCCTGGACATGGTGGAGCGCGAGTGCGGCACCA TCATCGAGGGCGTGAACACGCCCTACCTGTACTTCGGCATGTGGAAGACCACCTTCGCCTGGCACACCGAGGACATGGACCTGTACAGCA TCAACTACCTGCACTTTGGGGAGCCTAAGTCCTGGTACGCCATCCCACCAGAGCACGGCAAGCGCCTGGAGCGGCTGGCCATCGGCTTCT TCCCCGGGAGCTCGCAGGGCTGCGACGCCTTCCTGCGGCATAAGATGACCCTCATCTCGCCCATCATCCTGAAGAAGTACGGGATCCCCT TCAGCCGGATCACGCAGGAGGCCGGGGAATTCATGATCACATTTCCCTACGGCTACCACGCCGGCTTCAATCACGGGTTCAACTGCGCAG AATCTACCAACTTCGCCACCCTGCGGTGGATTGACTACGGCAAAGTGGCCACTCAGGACTCCTCCTATTTTGAGGACTTCTCCAACATCT CCATCTTCTCCTCGTCCGTGGACTCCCTGTCGGACATCGTGGACACGCCCGACTTCCTGCCGGCTGACAGCCTCAACCAGGTGTCCACCA TCTGGGACGATAACCCTGCCCCCTCCACCCACGATAAGCTGTTCCAGCTCAGCAGGCCGTTTGCAGGCTTCGAGGACTTTCTGCCCTCCC ACAGCACCCCGCTTCTCGTCAGCTACCAGGAGCAGAGTGTGCAGAGCCAGCCAGAGGAGGAGGACGAGGCTGAGGAGGAGGAGGCGGAGG AGCTGGGGCACACAGAGACCTACGCCGACTACGTGCCGTCCAAGTCCAAGATCGGGAAGCAGCACCCAGACCGCGTGGTGGAGACCAGCA CACTGTCCAGCGTCCCACCCCCAGACATCACCTACACCCTGGCCCTGCCCTCGGACAGCGGGGCCCTGTCTGCCCTGCAGCTAGAGGCCA TCACCTACGCCTGCCAGCAACACGAGGTCCTGCTCCCCAGCGGGCAGCGCGCGGGCTTTCTCATCGGCGATGGGGCCGGCGTGGGCAAAG GCCGGACGGTGGCCGGAGTCATCCTGGAGAACCACCTGCGCGGCCGGAAGAAAGCATTGTGGTTCAGCGTCTCCAACGACCTCAAGTACG ATGCGGAGCGCGACCTGCGGGACATCGAAGCCACGGGCATCGCGGTGCACGCGCTCAGCAAGATCAAGTACGGTGACACCACTACCTCAG AGGGCGTCCTCTTCGCCACCTACTCCGCCCTGATTGGGGAGAGCCAGGCCGGCGGCCAGCACCGCACTCGCCTCCGGCAGATCCTGGACT GGTGTGGGGAGGCCTTCGAGGGCGTCATCGTGTTCGACGAGTGTCACAAAGCCAAGAATGCCGGCTCCACCAAGATGGGCAAGGCTGTGC TAGACCTGCAGAACAAGCTGCCCCTGGCCCGCGTGGTCTACGCCAGCGCCACAGGTGCCTCTGAGCCTCGGAACATGATCTACATGAGCC GCTTGGGTATCTGGGGCGAGGGCACACCCTTCCGGAACTTTGAGGAGTTCCTGCACGCCATCGAGAAGAGGGGCGTTGGCGCCATGGAGA TCGTGGCCATGGACATGAAGGTCAGCGGCATGTACATCGCACGCCAGCTCAGCTTCTCCGGCGTCACCTTCCGCATCGAGGAGATCCCGC TGGCCCCAGCCTTCGAGTGCGTCTACAACCGCGCGGCCCTGCTGGCGGCCGACTGGATCGGCCTGGAGTCGCGCAAGTCCCTGTGGGGCC AGTTCTGGTCGGCACACCAGCGCTTCTTCAAGTATCTGTGCATCGCAGCCAAGGTGCGCCGGCTGGTGGAGCTGGCCCGAGAGGAGCTGG CGCGAGACAAGTGCGTGGTCATCGGGCTGCAGTCCACGGGCGAGGCGCGCACGCGGGAGGTGCTGGGGGAGAACGATGGGCACCTCAACT GCTTCGTCTCGGCCGCTGAAGGCGTGTTCCTGTCGCTAATTCAGAAGCACTTTCCGTCCACCAAGAGAAAGCGGGACAGAGGAGCGGGCA GCAAGCGGAAACGGCGACCTCGGGGACGCGGGGCCAAAGCCCCCCGGCTGGCGTGCGAGACAGCGGGCGTCATCCGCATCAGTGACGACA GCAGCACGGAGTCGGACCCTGGCCTGGACAGCGACTTCAACTCCTCCCCCGAGTCCCTGGTGGATGACGACGTTGTCATCGTTGATGCAG TCGGGCTCCCCAGTGACGACCGGGGACCCCTGTGCCTCCTGCAGAGAGACCCGCATGGCCCCGGGGTCCTGGAGCGGGTGGAGCGGCTGA AGCAGGATCTGCTGGACAAAGTGCGGCGGCTGGGCCGGGAACTGCCAGTCAACACCCTGGACGAGCTCATCGACCAGCTGGGCGGCCCCC AGCGGGTGGCGGAGATGACCGGCAGGAAAGGCCGCGTGGTGTCCAGGCCCGACGGGACGGTGGCCTTCGAGTCGCGGGCAGAGCAGGGTC TGTCCATCGACCACGTGAACCTCAGGGAGAAGCAGCGCTTCATGAGCGGCGAGAAGCTCGTGGCCATCATCTCGGAGGCCTCCAGCTCGG GTGTCTCCCTCCAAGCCGACCGCCGTGTCCAGAACCAGCGGCGCCGCGTGCACATGACCTTGGAGCTGCCGTGGAGCGCCGACCGCGCCA TCCAGCAGTTCGGCCGCACCCACCGGTCCAACCAGGTCTCCGCGCCAGAGTATGTCTTCCTCATCTCGGAGCTGGCCGGGGAGCGCCGGT TCGCCTCCATCGTGGCCAAGCGCCTGGAGAGTCTGGGGGCCCTGACCCACGGAGACCGCCGCGCCACGGAGTCCCGTGACCTCAGCAAGT ACAACTTTGAGAACAAGTATGGCACCCGGGCCCTGCACTGTGTCCTCACCACCATCCTGAGCCAGACTGAGAACAAAGTGCCTGTGCCCC AGGGATACCCTGGAGGGGTCCCCACCTTCTTCCGGGACATGAAGCAGGGCCTGCTGTCTGTGGGCATTGGTGGCCGGGAGTCCCGGAATG GCTGCCTGGACGTGGAGAAGGACTGTTCCATCACCAAGTTCCTGAACCGCATCCTGGGGCTGGAGGTGCACAAGCAGAACGCCCTGTTCC AGTACTTCTCAGACACCTTCGACCACCTCATCGAGATGGACAAGCGGGAGGGCAAATACGACATGGGCATCCTGGACCTTGCTCCCGGTA TCGAGGAGATCTACGAGGAGAGCCAGCAGGTGTTCCTGGCTCCCGGGCACCCGCAGGACGGGCAGGTGGTCTTCTACAAGATCAGCGTGG ACCGCGGCCTGAAGTGGGAGGACGCCTTTGCCAAGTCGCTGGCGCTGACGGGCCCCTATGACGGCTTCTACCTCTCCTACAAGGTCCGCG GTAACAAGCCCAGCTGCCTGCTGGCGGAGCAGAACCGCGGCCAGTTCTTCACGGTGTACAAGCCCAACATCGGCCGGCAGAGCCAGCTGG AGGCCCTGGACAGCCTCCGCCGCAAGTTCCACCGGGTCACCGCGGAGGAGGCCAAGGAGCCCTGGGAGAGTGGCTACGCTTTGTCGCTGA CGCACTGCAGCCACAGCGCCTGGAACCGGCACTGCCGGCTGGCGCAGGAGGGTAAGGACTGCCTGCAGGGGCTGCGGCTGCGGCACCACT ACATGCTGTGCGGCGCGCTGCTGCGCGTGTGGGGCCGCATCGCCGCCGTCATGGCCGACGTCAGCAGCAGCAGCTACCTGCAGATCGTGC GGCTGAAGACCAAGGACAGGAAGAAGCAAGTGGGCATCAAGATCCCCGAGGGCTGCGTGCGCCGGGTGCTGCAGGAGCTGCGGCTGATGG ATGCGGACGTGAAGCGCAGGCAGGCGCCCGCCCTGGGCTGCCCCGCCCCGCCCGCCCCGCGCCCGCTGGCGCTGCCTTGCGGCCCCGGAG AGGTGCTGGACCTCACCTACAGCCCCCCGGCCGAGGCCTTCCCGCCGCCCCCGCACTTCTCTTTCCCGGCGCCGCTGTCCCTGGACGCCG GCCCCGGCGTCGTGCCGCTGGGCACCCCCGACGCCCAGGCCGACCCTGCGGCCCTCGCGCACCAGGGCTGCGACATCAACTTCAAGGAGG TGCTGGAGGACATGCTGCGCTCGCTGCACGCGGGGCCGCCCTCCGAGGGCGCGCTGGGGGAGGGCGCGGGGGCGGGGGGCGCGGCGGGCG GTGGTCCCGAGCGGCAGAGCGTGATCCAGTTCAGCCCACCCTTCCCCGGCGCCCAGGCTCCTCTCTGACACGCCTTTAGGCGAAACATGC CCCAAGACACAGGGACCGTTTCTCCCCTAGGAGCAGCGGTGGGGAGCAGGGCCAAGGTCCCCTGACCACTGCTCAGAGGAGCCCTAGGCC CTGGCCGCAGTGCCTTCAGCGCCCGACCCGGGCCCCCACCTGGTCAGCCCTGGCGGGGCCCACTCAGGACAGCTGGGGGCCGGGGCGTGG CAGGGCCCTCTCTGTGCCTCTCCTCCCAAGTAGGAAGGGGCTCCGGGTGGCTGCTCTGGGACTGGGCACCCACAAGGGCTCAGTGGGCCC AAACCCTTGAAATCCGTGAAACCGGGTGGTCCCAAGAGCTAGAAACTCAGGAAACCCCAGGTGCTCAGGGCCCCGCGTCTCGGGGGCTCC GTGGGGCAGACCCCTGCTAATATATGCAATTCTCCCTCCCCCAGCCCTTCCCTGACCCCTAAGTTATTGCCCGCTCACCTCTCCCAGGCC CCAGGCCGCGGAGCTGGCAGGGTGGCGCCTGCGGTTTCTATGTATTTATAGCAAGTTCTGATGTACATATGTAAAGGACTTTTTTAAATA >In-frame_ENST00000159111_ENST00000587024_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(amino acids)=1569AA_start in transcript=218_stop in transcript=4927 MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQK KAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFG MWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMI TFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDK LFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYT LALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATG IAVHALSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVV YASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAA LLAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFVSAAEGVFLSL IQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGLPSDDRGPLCL LQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSIDHVNLREKQR FMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFASIVAKRLESLG ALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCLDVEKDCSITK FLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRGLKWEDAFAKS LALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHCSHSAWNRHCR LAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDADVKRRQAPALG CPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGP -------------------------------------------------------------- >In-frame_ENST00000159111_ENST00000438103_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(transcript)=5536nt_BP=1136nt GTCGCCAGCAACCGAGCGGGGCCCGGCCCGAGCGGGGCCTGGGGGTGCGACGCCGAGGGCGGGGGAGAGCGCGCCGCTGCTCCCGGACCG GGCCGCGCACGCCGCCTCAGGAACCATCACTGTTGCTGGAGGCACCTGACAAATCCTAGCGAATTTTTGGAGCATCTCCACCCAGGAACC TCGCCATCCAGAAGTGTGCTTCCCGCACAGCTGCAGCCATGGGGTCTGAGGACCACGGCGCCCAGAACCCCAGCTGTAAAATCATGACGT TTCGCCCAACCATGGAAGAATTTAAAGACTTCAACAAATACGTGGCCTACATAGAGTCGCAGGGAGCCCACCGGGCGGGCCTGGCCAAGA TCATCCCCCCGAAGGAGTGGAAGCCGCGGCAGACGTATGATGACATCGACGACGTGGTGATCCCGGCGCCCATCCAGCAGGTGGTGACGG GCCAGTCGGGCCTCTTCACGCAGTACAATATCCAGAAGAAGGCCATGACAGTGGGCGAGTACCGCCGCCTGGCCAACAGCGAGAAGTACT GTACCCCGCGGCACCAGGACTTTGATGACCTTGAACGCAAATACTGGAAGAACCTCACCTTTGTCTCCCCGATCTACGGGGCTGACATCA GCGGCTCTTTGTATGATGACGACGTGGCCCAGTGGAACATCGGGAGCCTCCGGACCATCCTGGACATGGTGGAGCGCGAGTGCGGCACCA TCATCGAGGGCGTGAACACGCCCTACCTGTACTTCGGCATGTGGAAGACCACCTTCGCCTGGCACACCGAGGACATGGACCTGTACAGCA TCAACTACCTGCACTTTGGGGAGCCTAAGTCCTGGTACGCCATCCCACCAGAGCACGGCAAGCGCCTGGAGCGGCTGGCCATCGGCTTCT TCCCCGGGAGCTCGCAGGGCTGCGACGCCTTCCTGCGGCATAAGATGACCCTCATCTCGCCCATCATCCTGAAGAAGTACGGGATCCCCT TCAGCCGGATCACGCAGGAGGCCGGGGAATTCATGATCACATTTCCCTACGGCTACCACGCCGGCTTCAATCACGGGTTCAACTGCGCAG AATCTACCAACTTCGCCACCCTGCGGTGGATTGACTACGGCAAAGTGGCCACTCAGGACTCCTCCTATTTTGAGGACTTCTCCAACATCT CCATCTTCTCCTCGTCCGTGGACTCCCTGTCGGACATCGTGGACACGCCCGACTTCCTGCCGGCTGACAGCCTCAACCAGGTGTCCACCA TCTGGGACGATAACCCTGCCCCCTCCACCCACGATAAGCTGTTCCAGCTCAGCAGGCCGTTTGCAGGCTTCGAGGACTTTCTGCCCTCCC ACAGCACCCCGCTTCTCGTCAGCTACCAGGAGCAGAGTGTGCAGAGCCAGCCAGAGGAGGAGGACGAGGCTGAGGAGGAGGAGGCGGAGG AGCTGGGGCACACAGAGACCTACGCCGACTACGTGCCGTCCAAGTCCAAGATCGGGAAGCAGCACCCAGACCGCGTGGTGGAGACCAGCA CACTGTCCAGCGTCCCACCCCCAGACATCACCTACACCCTGGCCCTGCCCTCGGACAGCGGGGCCCTGTCTGCCCTGCAGCTAGAGGCCA TCACCTACGCCTGCCAGCAACACGAGGTCCTGCTCCCCAGCGGGCAGCGCGCGGGCTTTCTCATCGGCGATGGGGCCGGCGTGGGCAAAG GCCGGACGGTGGCCGGAGTCATCCTGGAGAACCACCTGCGCGGCCGGAAGAAAGCATTGTGGTTCAGCGTCTCCAACGACCTCAAGTACG ATGCGGAGCGCGACCTGCGGGACATCGAAGCCACGGGCATCGCGGTGCACGCGCTCAGCAAGATCAAGTACGGTGACACCACTACCTCAG AGGGCGTCCTCTTCGCCACCTACTCCGCCCTGATTGGGGAGAGCCAGGCCGGCGGCCAGCACCGCACTCGCCTCCGGCAGATCCTGGACT GGTGTGGGGAGGCCTTCGAGGGCGTCATCGTGTTCGACGAGTGTCACAAAGCCAAGAATGCCGGCTCCACCAAGATGGGCAAGGCTGTGC TAGACCTGCAGAACAAGCTGCCCCTGGCCCGCGTGGTCTACGCCAGCGCCACAGGTGCCTCTGAGCCTCGGAACATGATCTACATGAGCC GCTTGGGTATCTGGGGCGAGGGCACACCCTTCCGGAACTTTGAGGAGTTCCTGCACGCCATCGAGAAGAGGGGCGTTGGCGCCATGGAGA TCGTGGCCATGGACATGAAGGTCAGCGGCATGTACATCGCACGCCAGCTCAGCTTCTCCGGCGTCACCTTCCGCATCGAGGAGATCCCGC TGGCCCCAGCCTTCGAGTGCGTCTACAACCGCGCGGCCCTGCTGTGGGCCGAGGCCCTGAACGTGTTCCAGCAGGCGGCCGACTGGATCG GCCTGGAGTCGCGCAAGTCCCTGTGGGGCCAGTTCTGGTCGGCACACCAGCGCTTCTTCAAGTATCTGTGCATCGCAGCCAAGGTGCGCC GGCTGGTGGAGCTGGCCCGAGAGGAGCTGGCGCGAGACAAGTGCGTGGTCATCGGGCTGCAGTCCACGGGCGAGGCGCGCACGCGGGAGG TGCTGGGGGAGAACGATGGGCACCTCAACTGCTTCGTCTCGGCCGCTGAAGGCGTGTTCCTGTCGCTAATTCAGAAGCACTTTCCGTCCA CCAAGAGAAAGCGGGACAGAGGAGCGGGCAGCAAGCGGAAACGGCGACCTCGGGGACGCGGGGCCAAAGCCCCCCGGCTGGCGTGCGAGA CAGCGGGCGTCATCCGCATCAGTGACGACAGCAGCACGGAGTCGGACCCTGGCCTGGACAGCGACTTCAACTCCTCCCCCGAGTCCCTGG TGGATGACGACGTTGTCATCGTTGATGCAGTCGGGCTCCCCAGTGACGACCGGGGACCCCTGTGCCTCCTGCAGAGAGACCCGCATGGCC CCGGGGTCCTGGAGCGGGTGGAGCGGCTGAAGCAGGATCTGCTGGACAAAGTGCGGCGGCTGGGCCGGGAACTGCCAGTCAACACCCTGG ACGAGCTCATCGACCAGCTGGGCGGCCCCCAGCGGGTGGCGGAGATGACCGGCAGGAAAGGCCGCGTGGTGTCCAGGCCCGACGGGACGG TGGCCTTCGAGTCGCGGGCAGAGCAGGGTCTGTCCATCGACCACGTGAACCTCAGGGAGAAGCAGCGCTTCATGAGCGGCGAGAAGCTCG TGGCCATCATCTCGGAGGCCTCCAGCTCGGGTGTCTCCCTCCAAGCCGACCGCCGTGTCCAGAACCAGCGGCGCCGCGTGCACATGACCT TGGAGCTGCCGTGGAGCGCCGACCGCGCCATCCAGCAGTTCGGCCGCACCCACCGGTCCAACCAGGTCTCCGCGCCAGAGTATGTCTTCC TCATCTCGGAGCTGGCCGGGGAGCGCCGGTTCGCCTCCATCGTGGCCAAGCGCCTGGAGAGTCTGGGGGCCCTGACCCACGGAGACCGCC GCGCCACGGAGTCCCGTGACCTCAGCAAGTACAACTTTGAGAACAAGTATGGCACCCGGGCCCTGCACTGTGTCCTCACCACCATCCTGA GCCAGACTGAGAACAAAGTGCCTGTGCCCCAGGGATACCCTGGAGGGGTCCCCACCTTCTTCCGGGACATGAAGCAGGGCCTGCTGTCTG TGGGCATTGGTGGCCGGGAGTCCCGGAATGGCTGCCTGGACGTGGAGAAGGACTGTTCCATCACCAAGTTCCTGAACCGCATCCTGGGGC TGGAGGTGCACAAGCAGAACGCCCTGTTCCAGTACTTCTCAGACACCTTCGACCACCTCATCGAGATGGACAAGCGGGAGGGCAAATACG ACATGGGCATCCTGGACCTTGCTCCCGGTATCGAGGAGATCTACGAGGAGAGCCAGCAGGTGTTCCTGGCTCCCGGGCACCCGCAGGACG GGCAGGTGGTCTTCTACAAGATCAGCGTGGACCGCGGCCTGAAGTGGGAGGACGCCTTTGCCAAGTCGCTGGCGCTGACGGGCCCCTATG ACGGCTTCTACCTCTCCTACAAGGTCCGCGGTAACAAGCCCAGCTGCCTGCTGGCGGAGCAGAACCGCGGCCAGTTCTTCACGGTGTACA AGCCCAACATCGGCCGGCAGAGCCAGCTGGAGGCCCTGGACAGCCTCCGCCGCAAGTTCCACCGGGTCACCGCGGAGGAGGCCAAGGAGC CCTGGGAGAGTGGCTACGCTTTGTCGCTGACGCACTGCAGCCACAGCGCCTGGAACCGGCACTGCCGGCTGGCGCAGGAGGGTAAGGACT GCCTGCAGGGGCTGCGGCTGCGGCACCACTACATGCTGTGCGGCGCGCTGCTGCGCGTGTGGGGCCGCATCGCCGCCGTCATGGCCGACG TCAGCAGCAGCAGCTACCTGCAGATCGTGCGGCTGAAGACCAAGGACAGGAAGAAGCAAGTGGGCATCAAGATCCCCGAGGGCTGCGTGC GCCGGGTGCTGCAGGAGCTGCGGCTGATGGATGCGGACGTGAAGCGCAGGCAGGCGCCCGCCCTGGGCTGCCCCGCCCCGCCCGCCCCGC GCCCGCTGGCGCTGCCTTGCGGCCCCGGAGAGGTGCTGGACCTCACCTACAGCCCCCCGGCCGAGGCCTTCCCGCCGCCCCCGCACTTCT CTTTCCCGGCGCCGCTGTCCCTGGACGCCGGCCCCGGCGTCGTGCCGCTGGGCACCCCCGACGCCCAGGCCGACCCTGCGGCCCTCGCGC ACCAGGGCTGCGACATCAACTTCAAGGAGGTGCTGGAGGACATGCTGCGCTCGCTGCACGCGGGGCCGCCCTCCGAGGGCGCGCTGGGGG AGGGCGCGGGGGCGGGGGGCGCGGCGGGCGGTGGTCCCGAGCGGCAGAGCGTGATCCAGTTCAGCCCACCCTTCCCCGGCGCCCAGGCTC CTCTCTGACACGCCTTTAGGCGAAACATGCCCCAAGACACAGGGACCGTTTCTCCCCTAGGAGCAGCGGTGGGGAGCAGGGCCAAGGTCC CCTGACCACTGCTCAGAGGAGCCCTAGGCCCTGGCCGCAGTGCCTTCAGCGCCCGACCCGGGCCCCCACCTGGTCAGCCCTGGCGGGGCC CACTCAGGACAGCTGGGGGCCGGGGCGTGGCAGGGCCCTCTCTGTGCCTCTCCTCCCAAGTAGGAAGGGGCTCCGGGTGGCTGCTCTGGG ACTGGGCACCCACAAGGGCTCAGTGGGCCCAAACCCTTGAAATCCGTGAAACCGGGTGGTCCCAAGAGCTAGAAACTCAGGAAACCCCAG GTGCTCAGGGCCCCGCGTCTCGGGGGCTCCGTGGGGCAGACCCCTGCTAATATATGCAATTCTCCCTCCCCCAGCCCTTCCCTGACCCCT AAGTTATTGCCCGCTCACCTCTCCCAGGCCCCAGGCCGCGGAGCTGGCAGGGTGGCGCCTGCGGTTTCTATGTATTTATAGCAAGTTCTG >In-frame_ENST00000159111_ENST00000438103_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(amino acids)=1579AA_start in transcript=218_stop in transcript=4957 MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQK KAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFG MWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMI TFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDK LFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYT LALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATG IAVHALSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVV YASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAA LLWAEALNVFQQAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFV SAAEGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGL PSDDRGPLCLLQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSI DHVNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFAS IVAKRLESLGALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCL DVEKDCSITKFLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRG LKWEDAFAKSLALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHC SHSAWNRHCRLAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDAD VKRRQAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLE -------------------------------------------------------------- >In-frame_ENST00000381759_ENST00000361757_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(transcript)=5530nt_BP=1125nt CCGAGCGGGGCCCGGCCCGAGCGGGGCCTGGGGGTGCGACGCCGAGGGCGGGGGAGAGCGCGCCGCTGCTCCCGGACCGGGCCGCGCACG CCGCCTCAGGAACCATCACTGTTGCTGGAGGCACCTGACAAATCCTAGCGAATTTTTGGAGCATCTCCACCCAGGAACCTCGCCATCCAG AAGTGTGCTTCCCGCACAGCTGCAGCCATGGGGTCTGAGGACCACGGCGCCCAGAACCCCAGCTGTAAAATCATGACGTTTCGCCCAACC ATGGAAGAATTTAAAGACTTCAACAAATACGTGGCCTACATAGAGTCGCAGGGAGCCCACCGGGCGGGCCTGGCCAAGATCATCCCCCCG AAGGAGTGGAAGCCGCGGCAGACGTATGATGACATCGACGACGTGGTGATCCCGGCGCCCATCCAGCAGGTGGTGACGGGCCAGTCGGGC CTCTTCACGCAGTACAATATCCAGAAGAAGGCCATGACAGTGGGCGAGTACCGCCGCCTGGCCAACAGCGAGAAGTACTGTACCCCGCGG CACCAGGACTTTGATGACCTTGAACGCAAATACTGGAAGAACCTCACCTTTGTCTCCCCGATCTACGGGGCTGACATCAGCGGCTCTTTG TATGATGACGACGTGGCCCAGTGGAACATCGGGAGCCTCCGGACCATCCTGGACATGGTGGAGCGCGAGTGCGGCACCATCATCGAGGGC GTGAACACGCCCTACCTGTACTTCGGCATGTGGAAGACCACCTTCGCCTGGCACACCGAGGACATGGACCTGTACAGCATCAACTACCTG CACTTTGGGGAGCCTAAGTCCTGGTACGCCATCCCACCAGAGCACGGCAAGCGCCTGGAGCGGCTGGCCATCGGCTTCTTCCCCGGGAGC TCGCAGGGCTGCGACGCCTTCCTGCGGCATAAGATGACCCTCATCTCGCCCATCATCCTGAAGAAGTACGGGATCCCCTTCAGCCGGATC ACGCAGGAGGCCGGGGAATTCATGATCACATTTCCCTACGGCTACCACGCCGGCTTCAATCACGGGTTCAACTGCGCAGAATCTACCAAC TTCGCCACCCTGCGGTGGATTGACTACGGCAAAGTGGCCACTCAGGACTCCTCCTATTTTGAGGACTTCTCCAACATCTCCATCTTCTCC TCGTCCGTGGACTCCCTGTCGGACATCGTGGACACGCCCGACTTCCTGCCGGCTGACAGCCTCAACCAGGTGTCCACCATCTGGGACGAT AACCCTGCCCCCTCCACCCACGATAAGCTGTTCCAGCTCAGCAGGCCGTTTGCAGGCTTCGAGGACTTTCTGCCCTCCCACAGCACCCCG CTTCTCGTCAGCTACCAGGAGCAGAGTGTGCAGAGCCAGCCAGAGGAGGAGGACGAGGCTGAGGAGGAGGAGGCGGAGGAGCTGGGGCAC ACAGAGACCTACGCCGACTACGTGCCGTCCAAGTCCAAGATCGGGAAGCAGCACCCAGACCGCGTGGTGGAGACCAGCACACTGTCCAGC GTCCCACCCCCAGACATCACCTACACCCTGGCCCTGCCCTCGGACAGCGGGGCCCTGTCTGCCCTGCAGCTAGAGGCCATCACCTACGCC TGCCAGCAACACGAGGTCCTGCTCCCCAGCGGGCAGCGCGCGGGCTTTCTCATCGGCGATGGGGCCGGCGTGGGCAAAGGCCGGACGGTG GCCGGAGTCATCCTGGAGAACCACCTGCGCGGCCGGAAGAAAGCATTGTGGTTCAGCGTCTCCAACGACCTCAAGTACGATGCGGAGCGC GACCTGCGGGACATCGAAGCCACGGGCATCGCGGTGCACGCGCTCAGCAAGATCAAGTACGGTGACACCACTACCTCAGAGGGCGTCCTC TTCGCCACCTACTCCGCCCTGATTGGGGAGAGCCAGGCCGGCGGCCAGCACCGCACTCGCCTCCGGCAGATCCTGGACTGGTGTGGGGAG GCCTTCGAGGGCGTCATCGTGTTCGACGAGTGTCACAAAGCCAAGAATGCCGGCTCCACCAAGATGGGCAAGGCTGTGCTAGACCTGCAG AACAAGCTGCCCCTGGCCCGCGTGGTCTACGCCAGCGCCACAGGTGCCTCTGAGCCTCGGAACATGATCTACATGAGCCGCTTGGGTATC TGGGGCGAGGGCACACCCTTCCGGAACTTTGAGGAGTTCCTGCACGCCATCGAGAAGAGGGGCGTTGGCGCCATGGAGATCGTGGCCATG GACATGAAGGTCAGCGGCATGTACATCGCACGCCAGCTCAGCTTCTCCGGCGTCACCTTCCGCATCGAGGAGATCCCGCTGGCCCCAGCC TTCGAGTGCGTCTACAACCGCGCGGCCCTGCTGTGGGCCGAGGCCCTGAACGTGTTCCAGCAGGCGGCCGACTGGATCGGCCTGGAGTCG CGCAAGTCCCTGTGGGGCCAGTTCTGGTCGGCACACCAGCGCTTCTTCAAGTATCTGTGCATCGCAGCCAAGGTGCGCCGGCTGGTGGAG CTGGCCCGAGAGGAGCTGGCGCGAGACAAGTGCGTGGTCATCGGGCTGCAGTCCACGGGCGAGGCGCGCACGCGGGAGGTGCTGGGGGAG AACGATGGGCACCTCAACTGCTTCGTCTCGGCCGCTGAAGGCGTGTTCCTGTCGCTAATTCAGAAGCACTTTCCGTCCACCAAGAGAAAG CGGGACAGAGGAGCGGGCAGCAAGCGGAAACGGCGACCTCGGGGACGCGGGGCCAAAGCCCCCCGGCTGGCGTGCGAGACAGCGGGCGTC ATCCGCATCAGTGACGACAGCAGCACGGAGTCGGACCCTGGCCTGGACAGCGACTTCAACTCCTCCCCCGAGTCCCTGGTGGATGACGAC GTTGTCATCGTTGATGCAGTCGGGCTCCCCAGTGACGACCGGGGACCCCTGTGCCTCCTGCAGAGAGACCCGCATGGCCCCGGGGTCCTG GAGCGGGTGGAGCGGCTGAAGCAGGATCTGCTGGACAAAGTGCGGCGGCTGGGCCGGGAACTGCCAGTCAACACCCTGGACGAGCTCATC GACCAGCTGGGCGGCCCCCAGCGGGTGGCGGAGATGACCGGCAGGAAAGGCCGCGTGGTGTCCAGGCCCGACGGGACGGTGGCCTTCGAG TCGCGGGCAGAGCAGGGTCTGTCCATCGACCACGTGAACCTCAGGGAGAAGCAGCGCTTCATGAGCGGCGAGAAGCTCGTGGCCATCATC TCGGAGGCCTCCAGCTCGGGTGTCTCCCTCCAAGCCGACCGCCGTGTCCAGAACCAGCGGCGCCGCGTGCACATGACCTTGGAGCTGCCG TGGAGCGCCGACCGCGCCATCCAGCAGTTCGGCCGCACCCACCGGTCCAACCAGGTCTCCGCGCCAGAGTATGTCTTCCTCATCTCGGAG CTGGCCGGGGAGCGCCGGTTCGCCTCCATCGTGGCCAAGCGCCTGGAGAGTCTGGGGGCCCTGACCCACGGAGACCGCCGCGCCACGGAG TCCCGTGACCTCAGCAAGTACAACTTTGAGAACAAGTATGGCACCCGGGCCCTGCACTGTGTCCTCACCACCATCCTGAGCCAGACTGAG AACAAAGTGCCTGTGCCCCAGGGATACCCTGGAGGGGTCCCCACCTTCTTCCGGGACATGAAGCAGGGCCTGCTGTCTGTGGGCATTGGT GGCCGGGAGTCCCGGAATGGCTGCCTGGACGTGGAGAAGGACTGTTCCATCACCAAGTTCCTGAACCGCATCCTGGGGCTGGAGGTGCAC AAGCAGAACGCCCTGTTCCAGTACTTCTCAGACACCTTCGACCACCTCATCGAGATGGACAAGCGGGAGGGCAAATACGACATGGGCATC CTGGACCTTGCTCCCGGTATCGAGGAGATCTACGAGGAGAGCCAGCAGGTGTTCCTGGCTCCCGGGCACCCGCAGGACGGGCAGGTGGTC TTCTACAAGATCAGCGTGGACCGCGGCCTGAAGTGGGAGGACGCCTTTGCCAAGTCGCTGGCGCTGACGGGCCCCTATGACGGCTTCTAC CTCTCCTACAAGGTCCGCGGTAACAAGCCCAGCTGCCTGCTGGCGGAGCAGAACCGCGGCCAGTTCTTCACGGTGTACAAGCCCAACATC GGCCGGCAGAGCCAGCTGGAGGCCCTGGACAGCCTCCGCCGCAAGTTCCACCGGGTCACCGCGGAGGAGGCCAAGGAGCCCTGGGAGAGT GGCTACGCTTTGTCGCTGACGCACTGCAGCCACAGCGCCTGGAACCGGCACTGCCGGCTGGCGCAGGAGGGTAAGGACTGCCTGCAGGGG CTGCGGCTGCGGCACCACTACATGCTGTGCGGCGCGCTGCTGCGCGTGTGGGGCCGCATCGCCGCCGTCATGGCCGACGTCAGCAGCAGC AGCTACCTGCAGATCGTGCGGCTGAAGACCAAGGACAGGAAGAAGCAAGTGGGCATCAAGATCCCCGAGGGCTGCGTGCGCCGGGTGCTG CAGGAGCTGCGGCTGATGGATGCGGACGTGAAGCGCAGGCAGGCGCCCGCCCTGGGCTGCCCCGCCCCGCCCGCCCCGCGCCCGCTGGCG CTGCCTTGCGGCCCCGGAGAGGTGCTGGACCTCACCTACAGCCCCCCGGCCGAGGCCTTCCCGCCGCCCCCGCACTTCTCTTTCCCGGCG CCGCTGTCCCTGGACGCCGGCCCCGGCGTCGTGCCGCTGGGCACCCCCGACGCCCAGGCCGACCCTGCGGCCCTCGCGCACCAGGGCTGC GACATCAACTTCAAGGAGGTGCTGGAGGACATGCTGCGCTCGCTGCACGCGGGGCCGCCCTCCGAGGGCGCGCTGGGGGAGGGCGCGGGG GCGGGGGGCGCGGCGGGCGGTGGTCCCGAGCGGCAGAGCGTGATCCAGTTCAGCCCACCCTTCCCCGGCGCCCAGGCTCCTCTCTGACAC GCCTTTAGGCGAAACATGCCCCAAGACACAGGGACCGTTTCTCCCCTAGGAGCAGCGGTGGGGAGCAGGGCCAAGGTCCCCTGACCACTG CTCAGAGGAGCCCTAGGCCCTGGCCGCAGTGCCTTCAGCGCCCGACCCGGGCCCCCACCTGGTCAGCCCTGGCGGGGCCCACTCAGGACA GCTGGGGGCCGGGGCGTGGCAGGGCCCTCTCTGTGCCTCTCCTCCCAAGTAGGAAGGGGCTCCGGGTGGCTGCTCTGGGACTGGGCACCC ACAAGGGCTCAGTGGGCCCAAACCCTTGAAATCCGTGAAACCGGGTGGTCCCAAGAGCTAGAAACTCAGGAAACCCCAGGTGCTCAGGGC CCCGCGTCTCGGGGGCTCCGTGGGGCAGACCCCTGCTAATATATGCAATTCTCCCTCCCCCAGCCCTTCCCTGACCCCTAAGTTATTGCC CGCTCACCTCTCCCAGGCCCCAGGCCGCGGAGCTGGCAGGGTGGCGCCTGCGGTTTCTATGTATTTATAGCAAGTTCTGATGTACATATG >In-frame_ENST00000381759_ENST00000361757_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(amino acids)=1579AA_start in transcript=207_stop in transcript=4946 MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQK KAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFG MWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMI TFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDK LFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYT LALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATG IAVHALSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVV YASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAA LLWAEALNVFQQAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFV SAAEGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGL PSDDRGPLCLLQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSI DHVNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFAS IVAKRLESLGALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCL DVEKDCSITKFLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRG LKWEDAFAKSLALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHC SHSAWNRHCRLAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDAD VKRRQAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLE -------------------------------------------------------------- >In-frame_ENST00000381759_ENST00000587024_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(transcript)=5496nt_BP=1125nt CCGAGCGGGGCCCGGCCCGAGCGGGGCCTGGGGGTGCGACGCCGAGGGCGGGGGAGAGCGCGCCGCTGCTCCCGGACCGGGCCGCGCACG CCGCCTCAGGAACCATCACTGTTGCTGGAGGCACCTGACAAATCCTAGCGAATTTTTGGAGCATCTCCACCCAGGAACCTCGCCATCCAG AAGTGTGCTTCCCGCACAGCTGCAGCCATGGGGTCTGAGGACCACGGCGCCCAGAACCCCAGCTGTAAAATCATGACGTTTCGCCCAACC ATGGAAGAATTTAAAGACTTCAACAAATACGTGGCCTACATAGAGTCGCAGGGAGCCCACCGGGCGGGCCTGGCCAAGATCATCCCCCCG AAGGAGTGGAAGCCGCGGCAGACGTATGATGACATCGACGACGTGGTGATCCCGGCGCCCATCCAGCAGGTGGTGACGGGCCAGTCGGGC CTCTTCACGCAGTACAATATCCAGAAGAAGGCCATGACAGTGGGCGAGTACCGCCGCCTGGCCAACAGCGAGAAGTACTGTACCCCGCGG CACCAGGACTTTGATGACCTTGAACGCAAATACTGGAAGAACCTCACCTTTGTCTCCCCGATCTACGGGGCTGACATCAGCGGCTCTTTG TATGATGACGACGTGGCCCAGTGGAACATCGGGAGCCTCCGGACCATCCTGGACATGGTGGAGCGCGAGTGCGGCACCATCATCGAGGGC GTGAACACGCCCTACCTGTACTTCGGCATGTGGAAGACCACCTTCGCCTGGCACACCGAGGACATGGACCTGTACAGCATCAACTACCTG CACTTTGGGGAGCCTAAGTCCTGGTACGCCATCCCACCAGAGCACGGCAAGCGCCTGGAGCGGCTGGCCATCGGCTTCTTCCCCGGGAGC TCGCAGGGCTGCGACGCCTTCCTGCGGCATAAGATGACCCTCATCTCGCCCATCATCCTGAAGAAGTACGGGATCCCCTTCAGCCGGATC ACGCAGGAGGCCGGGGAATTCATGATCACATTTCCCTACGGCTACCACGCCGGCTTCAATCACGGGTTCAACTGCGCAGAATCTACCAAC TTCGCCACCCTGCGGTGGATTGACTACGGCAAAGTGGCCACTCAGGACTCCTCCTATTTTGAGGACTTCTCCAACATCTCCATCTTCTCC TCGTCCGTGGACTCCCTGTCGGACATCGTGGACACGCCCGACTTCCTGCCGGCTGACAGCCTCAACCAGGTGTCCACCATCTGGGACGAT AACCCTGCCCCCTCCACCCACGATAAGCTGTTCCAGCTCAGCAGGCCGTTTGCAGGCTTCGAGGACTTTCTGCCCTCCCACAGCACCCCG CTTCTCGTCAGCTACCAGGAGCAGAGTGTGCAGAGCCAGCCAGAGGAGGAGGACGAGGCTGAGGAGGAGGAGGCGGAGGAGCTGGGGCAC ACAGAGACCTACGCCGACTACGTGCCGTCCAAGTCCAAGATCGGGAAGCAGCACCCAGACCGCGTGGTGGAGACCAGCACACTGTCCAGC GTCCCACCCCCAGACATCACCTACACCCTGGCCCTGCCCTCGGACAGCGGGGCCCTGTCTGCCCTGCAGCTAGAGGCCATCACCTACGCC TGCCAGCAACACGAGGTCCTGCTCCCCAGCGGGCAGCGCGCGGGCTTTCTCATCGGCGATGGGGCCGGCGTGGGCAAAGGCCGGACGGTG GCCGGAGTCATCCTGGAGAACCACCTGCGCGGCCGGAAGAAAGCATTGTGGTTCAGCGTCTCCAACGACCTCAAGTACGATGCGGAGCGC GACCTGCGGGACATCGAAGCCACGGGCATCGCGGTGCACGCGCTCAGCAAGATCAAGTACGGTGACACCACTACCTCAGAGGGCGTCCTC TTCGCCACCTACTCCGCCCTGATTGGGGAGAGCCAGGCCGGCGGCCAGCACCGCACTCGCCTCCGGCAGATCCTGGACTGGTGTGGGGAG GCCTTCGAGGGCGTCATCGTGTTCGACGAGTGTCACAAAGCCAAGAATGCCGGCTCCACCAAGATGGGCAAGGCTGTGCTAGACCTGCAG AACAAGCTGCCCCTGGCCCGCGTGGTCTACGCCAGCGCCACAGGTGCCTCTGAGCCTCGGAACATGATCTACATGAGCCGCTTGGGTATC TGGGGCGAGGGCACACCCTTCCGGAACTTTGAGGAGTTCCTGCACGCCATCGAGAAGAGGGGCGTTGGCGCCATGGAGATCGTGGCCATG GACATGAAGGTCAGCGGCATGTACATCGCACGCCAGCTCAGCTTCTCCGGCGTCACCTTCCGCATCGAGGAGATCCCGCTGGCCCCAGCC TTCGAGTGCGTCTACAACCGCGCGGCCCTGCTGGCGGCCGACTGGATCGGCCTGGAGTCGCGCAAGTCCCTGTGGGGCCAGTTCTGGTCG GCACACCAGCGCTTCTTCAAGTATCTGTGCATCGCAGCCAAGGTGCGCCGGCTGGTGGAGCTGGCCCGAGAGGAGCTGGCGCGAGACAAG TGCGTGGTCATCGGGCTGCAGTCCACGGGCGAGGCGCGCACGCGGGAGGTGCTGGGGGAGAACGATGGGCACCTCAACTGCTTCGTCTCG GCCGCTGAAGGCGTGTTCCTGTCGCTAATTCAGAAGCACTTTCCGTCCACCAAGAGAAAGCGGGACAGAGGAGCGGGCAGCAAGCGGAAA CGGCGACCTCGGGGACGCGGGGCCAAAGCCCCCCGGCTGGCGTGCGAGACAGCGGGCGTCATCCGCATCAGTGACGACAGCAGCACGGAG TCGGACCCTGGCCTGGACAGCGACTTCAACTCCTCCCCCGAGTCCCTGGTGGATGACGACGTTGTCATCGTTGATGCAGTCGGGCTCCCC AGTGACGACCGGGGACCCCTGTGCCTCCTGCAGAGAGACCCGCATGGCCCCGGGGTCCTGGAGCGGGTGGAGCGGCTGAAGCAGGATCTG CTGGACAAAGTGCGGCGGCTGGGCCGGGAACTGCCAGTCAACACCCTGGACGAGCTCATCGACCAGCTGGGCGGCCCCCAGCGGGTGGCG GAGATGACCGGCAGGAAAGGCCGCGTGGTGTCCAGGCCCGACGGGACGGTGGCCTTCGAGTCGCGGGCAGAGCAGGGTCTGTCCATCGAC CACGTGAACCTCAGGGAGAAGCAGCGCTTCATGAGCGGCGAGAAGCTCGTGGCCATCATCTCGGAGGCCTCCAGCTCGGGTGTCTCCCTC CAAGCCGACCGCCGTGTCCAGAACCAGCGGCGCCGCGTGCACATGACCTTGGAGCTGCCGTGGAGCGCCGACCGCGCCATCCAGCAGTTC GGCCGCACCCACCGGTCCAACCAGGTCTCCGCGCCAGAGTATGTCTTCCTCATCTCGGAGCTGGCCGGGGAGCGCCGGTTCGCCTCCATC GTGGCCAAGCGCCTGGAGAGTCTGGGGGCCCTGACCCACGGAGACCGCCGCGCCACGGAGTCCCGTGACCTCAGCAAGTACAACTTTGAG AACAAGTATGGCACCCGGGCCCTGCACTGTGTCCTCACCACCATCCTGAGCCAGACTGAGAACAAAGTGCCTGTGCCCCAGGGATACCCT GGAGGGGTCCCCACCTTCTTCCGGGACATGAAGCAGGGCCTGCTGTCTGTGGGCATTGGTGGCCGGGAGTCCCGGAATGGCTGCCTGGAC GTGGAGAAGGACTGTTCCATCACCAAGTTCCTGAACCGCATCCTGGGGCTGGAGGTGCACAAGCAGAACGCCCTGTTCCAGTACTTCTCA GACACCTTCGACCACCTCATCGAGATGGACAAGCGGGAGGGCAAATACGACATGGGCATCCTGGACCTTGCTCCCGGTATCGAGGAGATC TACGAGGAGAGCCAGCAGGTGTTCCTGGCTCCCGGGCACCCGCAGGACGGGCAGGTGGTCTTCTACAAGATCAGCGTGGACCGCGGCCTG AAGTGGGAGGACGCCTTTGCCAAGTCGCTGGCGCTGACGGGCCCCTATGACGGCTTCTACCTCTCCTACAAGGTCCGCGGTAACAAGCCC AGCTGCCTGCTGGCGGAGCAGAACCGCGGCCAGTTCTTCACGGTGTACAAGCCCAACATCGGCCGGCAGAGCCAGCTGGAGGCCCTGGAC AGCCTCCGCCGCAAGTTCCACCGGGTCACCGCGGAGGAGGCCAAGGAGCCCTGGGAGAGTGGCTACGCTTTGTCGCTGACGCACTGCAGC CACAGCGCCTGGAACCGGCACTGCCGGCTGGCGCAGGAGGGTAAGGACTGCCTGCAGGGGCTGCGGCTGCGGCACCACTACATGCTGTGC GGCGCGCTGCTGCGCGTGTGGGGCCGCATCGCCGCCGTCATGGCCGACGTCAGCAGCAGCAGCTACCTGCAGATCGTGCGGCTGAAGACC AAGGACAGGAAGAAGCAAGTGGGCATCAAGATCCCCGAGGGCTGCGTGCGCCGGGTGCTGCAGGAGCTGCGGCTGATGGATGCGGACGTG AAGCGCAGGCAGGCGCCCGCCCTGGGCTGCCCCGCCCCGCCCGCCCCGCGCCCGCTGGCGCTGCCTTGCGGCCCCGGAGAGGTGCTGGAC CTCACCTACAGCCCCCCGGCCGAGGCCTTCCCGCCGCCCCCGCACTTCTCTTTCCCGGCGCCGCTGTCCCTGGACGCCGGCCCCGGCGTC GTGCCGCTGGGCACCCCCGACGCCCAGGCCGACCCTGCGGCCCTCGCGCACCAGGGCTGCGACATCAACTTCAAGGAGGTGCTGGAGGAC ATGCTGCGCTCGCTGCACGCGGGGCCGCCCTCCGAGGGCGCGCTGGGGGAGGGCGCGGGGGCGGGGGGCGCGGCGGGCGGTGGTCCCGAG CGGCAGAGCGTGATCCAGTTCAGCCCACCCTTCCCCGGCGCCCAGGCTCCTCTCTGACACGCCTTTAGGCGAAACATGCCCCAAGACACA GGGACCGTTTCTCCCCTAGGAGCAGCGGTGGGGAGCAGGGCCAAGGTCCCCTGACCACTGCTCAGAGGAGCCCTAGGCCCTGGCCGCAGT GCCTTCAGCGCCCGACCCGGGCCCCCACCTGGTCAGCCCTGGCGGGGCCCACTCAGGACAGCTGGGGGCCGGGGCGTGGCAGGGCCCTCT CTGTGCCTCTCCTCCCAAGTAGGAAGGGGCTCCGGGTGGCTGCTCTGGGACTGGGCACCCACAAGGGCTCAGTGGGCCCAAACCCTTGAA ATCCGTGAAACCGGGTGGTCCCAAGAGCTAGAAACTCAGGAAACCCCAGGTGCTCAGGGCCCCGCGTCTCGGGGGCTCCGTGGGGCAGAC CCCTGCTAATATATGCAATTCTCCCTCCCCCAGCCCTTCCCTGACCCCTAAGTTATTGCCCGCTCACCTCTCCCAGGCCCCAGGCCGCGG AGCTGGCAGGGTGGCGCCTGCGGTTTCTATGTATTTATAGCAAGTTCTGATGTACATATGTAAAGGACTTTTTTAAATATATGTGCCTTT >In-frame_ENST00000381759_ENST00000587024_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(amino acids)=1569AA_start in transcript=207_stop in transcript=4916 MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQK KAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFG MWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMI TFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDK LFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYT LALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATG IAVHALSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVV YASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAA LLAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFVSAAEGVFLSL IQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGLPSDDRGPLCL LQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSIDHVNLREKQR FMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFASIVAKRLESLG ALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCLDVEKDCSITK FLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRGLKWEDAFAKS LALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHCSHSAWNRHCR LAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDADVKRRQAPALG CPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGP -------------------------------------------------------------- >In-frame_ENST00000381759_ENST00000438103_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(transcript)=5525nt_BP=1125nt CCGAGCGGGGCCCGGCCCGAGCGGGGCCTGGGGGTGCGACGCCGAGGGCGGGGGAGAGCGCGCCGCTGCTCCCGGACCGGGCCGCGCACG CCGCCTCAGGAACCATCACTGTTGCTGGAGGCACCTGACAAATCCTAGCGAATTTTTGGAGCATCTCCACCCAGGAACCTCGCCATCCAG AAGTGTGCTTCCCGCACAGCTGCAGCCATGGGGTCTGAGGACCACGGCGCCCAGAACCCCAGCTGTAAAATCATGACGTTTCGCCCAACC ATGGAAGAATTTAAAGACTTCAACAAATACGTGGCCTACATAGAGTCGCAGGGAGCCCACCGGGCGGGCCTGGCCAAGATCATCCCCCCG AAGGAGTGGAAGCCGCGGCAGACGTATGATGACATCGACGACGTGGTGATCCCGGCGCCCATCCAGCAGGTGGTGACGGGCCAGTCGGGC CTCTTCACGCAGTACAATATCCAGAAGAAGGCCATGACAGTGGGCGAGTACCGCCGCCTGGCCAACAGCGAGAAGTACTGTACCCCGCGG CACCAGGACTTTGATGACCTTGAACGCAAATACTGGAAGAACCTCACCTTTGTCTCCCCGATCTACGGGGCTGACATCAGCGGCTCTTTG TATGATGACGACGTGGCCCAGTGGAACATCGGGAGCCTCCGGACCATCCTGGACATGGTGGAGCGCGAGTGCGGCACCATCATCGAGGGC GTGAACACGCCCTACCTGTACTTCGGCATGTGGAAGACCACCTTCGCCTGGCACACCGAGGACATGGACCTGTACAGCATCAACTACCTG CACTTTGGGGAGCCTAAGTCCTGGTACGCCATCCCACCAGAGCACGGCAAGCGCCTGGAGCGGCTGGCCATCGGCTTCTTCCCCGGGAGC TCGCAGGGCTGCGACGCCTTCCTGCGGCATAAGATGACCCTCATCTCGCCCATCATCCTGAAGAAGTACGGGATCCCCTTCAGCCGGATC ACGCAGGAGGCCGGGGAATTCATGATCACATTTCCCTACGGCTACCACGCCGGCTTCAATCACGGGTTCAACTGCGCAGAATCTACCAAC TTCGCCACCCTGCGGTGGATTGACTACGGCAAAGTGGCCACTCAGGACTCCTCCTATTTTGAGGACTTCTCCAACATCTCCATCTTCTCC TCGTCCGTGGACTCCCTGTCGGACATCGTGGACACGCCCGACTTCCTGCCGGCTGACAGCCTCAACCAGGTGTCCACCATCTGGGACGAT AACCCTGCCCCCTCCACCCACGATAAGCTGTTCCAGCTCAGCAGGCCGTTTGCAGGCTTCGAGGACTTTCTGCCCTCCCACAGCACCCCG CTTCTCGTCAGCTACCAGGAGCAGAGTGTGCAGAGCCAGCCAGAGGAGGAGGACGAGGCTGAGGAGGAGGAGGCGGAGGAGCTGGGGCAC ACAGAGACCTACGCCGACTACGTGCCGTCCAAGTCCAAGATCGGGAAGCAGCACCCAGACCGCGTGGTGGAGACCAGCACACTGTCCAGC GTCCCACCCCCAGACATCACCTACACCCTGGCCCTGCCCTCGGACAGCGGGGCCCTGTCTGCCCTGCAGCTAGAGGCCATCACCTACGCC TGCCAGCAACACGAGGTCCTGCTCCCCAGCGGGCAGCGCGCGGGCTTTCTCATCGGCGATGGGGCCGGCGTGGGCAAAGGCCGGACGGTG GCCGGAGTCATCCTGGAGAACCACCTGCGCGGCCGGAAGAAAGCATTGTGGTTCAGCGTCTCCAACGACCTCAAGTACGATGCGGAGCGC GACCTGCGGGACATCGAAGCCACGGGCATCGCGGTGCACGCGCTCAGCAAGATCAAGTACGGTGACACCACTACCTCAGAGGGCGTCCTC TTCGCCACCTACTCCGCCCTGATTGGGGAGAGCCAGGCCGGCGGCCAGCACCGCACTCGCCTCCGGCAGATCCTGGACTGGTGTGGGGAG GCCTTCGAGGGCGTCATCGTGTTCGACGAGTGTCACAAAGCCAAGAATGCCGGCTCCACCAAGATGGGCAAGGCTGTGCTAGACCTGCAG AACAAGCTGCCCCTGGCCCGCGTGGTCTACGCCAGCGCCACAGGTGCCTCTGAGCCTCGGAACATGATCTACATGAGCCGCTTGGGTATC TGGGGCGAGGGCACACCCTTCCGGAACTTTGAGGAGTTCCTGCACGCCATCGAGAAGAGGGGCGTTGGCGCCATGGAGATCGTGGCCATG GACATGAAGGTCAGCGGCATGTACATCGCACGCCAGCTCAGCTTCTCCGGCGTCACCTTCCGCATCGAGGAGATCCCGCTGGCCCCAGCC TTCGAGTGCGTCTACAACCGCGCGGCCCTGCTGTGGGCCGAGGCCCTGAACGTGTTCCAGCAGGCGGCCGACTGGATCGGCCTGGAGTCG CGCAAGTCCCTGTGGGGCCAGTTCTGGTCGGCACACCAGCGCTTCTTCAAGTATCTGTGCATCGCAGCCAAGGTGCGCCGGCTGGTGGAG CTGGCCCGAGAGGAGCTGGCGCGAGACAAGTGCGTGGTCATCGGGCTGCAGTCCACGGGCGAGGCGCGCACGCGGGAGGTGCTGGGGGAG AACGATGGGCACCTCAACTGCTTCGTCTCGGCCGCTGAAGGCGTGTTCCTGTCGCTAATTCAGAAGCACTTTCCGTCCACCAAGAGAAAG CGGGACAGAGGAGCGGGCAGCAAGCGGAAACGGCGACCTCGGGGACGCGGGGCCAAAGCCCCCCGGCTGGCGTGCGAGACAGCGGGCGTC ATCCGCATCAGTGACGACAGCAGCACGGAGTCGGACCCTGGCCTGGACAGCGACTTCAACTCCTCCCCCGAGTCCCTGGTGGATGACGAC GTTGTCATCGTTGATGCAGTCGGGCTCCCCAGTGACGACCGGGGACCCCTGTGCCTCCTGCAGAGAGACCCGCATGGCCCCGGGGTCCTG GAGCGGGTGGAGCGGCTGAAGCAGGATCTGCTGGACAAAGTGCGGCGGCTGGGCCGGGAACTGCCAGTCAACACCCTGGACGAGCTCATC GACCAGCTGGGCGGCCCCCAGCGGGTGGCGGAGATGACCGGCAGGAAAGGCCGCGTGGTGTCCAGGCCCGACGGGACGGTGGCCTTCGAG TCGCGGGCAGAGCAGGGTCTGTCCATCGACCACGTGAACCTCAGGGAGAAGCAGCGCTTCATGAGCGGCGAGAAGCTCGTGGCCATCATC TCGGAGGCCTCCAGCTCGGGTGTCTCCCTCCAAGCCGACCGCCGTGTCCAGAACCAGCGGCGCCGCGTGCACATGACCTTGGAGCTGCCG TGGAGCGCCGACCGCGCCATCCAGCAGTTCGGCCGCACCCACCGGTCCAACCAGGTCTCCGCGCCAGAGTATGTCTTCCTCATCTCGGAG CTGGCCGGGGAGCGCCGGTTCGCCTCCATCGTGGCCAAGCGCCTGGAGAGTCTGGGGGCCCTGACCCACGGAGACCGCCGCGCCACGGAG TCCCGTGACCTCAGCAAGTACAACTTTGAGAACAAGTATGGCACCCGGGCCCTGCACTGTGTCCTCACCACCATCCTGAGCCAGACTGAG AACAAAGTGCCTGTGCCCCAGGGATACCCTGGAGGGGTCCCCACCTTCTTCCGGGACATGAAGCAGGGCCTGCTGTCTGTGGGCATTGGT GGCCGGGAGTCCCGGAATGGCTGCCTGGACGTGGAGAAGGACTGTTCCATCACCAAGTTCCTGAACCGCATCCTGGGGCTGGAGGTGCAC AAGCAGAACGCCCTGTTCCAGTACTTCTCAGACACCTTCGACCACCTCATCGAGATGGACAAGCGGGAGGGCAAATACGACATGGGCATC CTGGACCTTGCTCCCGGTATCGAGGAGATCTACGAGGAGAGCCAGCAGGTGTTCCTGGCTCCCGGGCACCCGCAGGACGGGCAGGTGGTC TTCTACAAGATCAGCGTGGACCGCGGCCTGAAGTGGGAGGACGCCTTTGCCAAGTCGCTGGCGCTGACGGGCCCCTATGACGGCTTCTAC CTCTCCTACAAGGTCCGCGGTAACAAGCCCAGCTGCCTGCTGGCGGAGCAGAACCGCGGCCAGTTCTTCACGGTGTACAAGCCCAACATC GGCCGGCAGAGCCAGCTGGAGGCCCTGGACAGCCTCCGCCGCAAGTTCCACCGGGTCACCGCGGAGGAGGCCAAGGAGCCCTGGGAGAGT GGCTACGCTTTGTCGCTGACGCACTGCAGCCACAGCGCCTGGAACCGGCACTGCCGGCTGGCGCAGGAGGGTAAGGACTGCCTGCAGGGG CTGCGGCTGCGGCACCACTACATGCTGTGCGGCGCGCTGCTGCGCGTGTGGGGCCGCATCGCCGCCGTCATGGCCGACGTCAGCAGCAGC AGCTACCTGCAGATCGTGCGGCTGAAGACCAAGGACAGGAAGAAGCAAGTGGGCATCAAGATCCCCGAGGGCTGCGTGCGCCGGGTGCTG CAGGAGCTGCGGCTGATGGATGCGGACGTGAAGCGCAGGCAGGCGCCCGCCCTGGGCTGCCCCGCCCCGCCCGCCCCGCGCCCGCTGGCG CTGCCTTGCGGCCCCGGAGAGGTGCTGGACCTCACCTACAGCCCCCCGGCCGAGGCCTTCCCGCCGCCCCCGCACTTCTCTTTCCCGGCG CCGCTGTCCCTGGACGCCGGCCCCGGCGTCGTGCCGCTGGGCACCCCCGACGCCCAGGCCGACCCTGCGGCCCTCGCGCACCAGGGCTGC GACATCAACTTCAAGGAGGTGCTGGAGGACATGCTGCGCTCGCTGCACGCGGGGCCGCCCTCCGAGGGCGCGCTGGGGGAGGGCGCGGGG GCGGGGGGCGCGGCGGGCGGTGGTCCCGAGCGGCAGAGCGTGATCCAGTTCAGCCCACCCTTCCCCGGCGCCCAGGCTCCTCTCTGACAC GCCTTTAGGCGAAACATGCCCCAAGACACAGGGACCGTTTCTCCCCTAGGAGCAGCGGTGGGGAGCAGGGCCAAGGTCCCCTGACCACTG CTCAGAGGAGCCCTAGGCCCTGGCCGCAGTGCCTTCAGCGCCCGACCCGGGCCCCCACCTGGTCAGCCCTGGCGGGGCCCACTCAGGACA GCTGGGGGCCGGGGCGTGGCAGGGCCCTCTCTGTGCCTCTCCTCCCAAGTAGGAAGGGGCTCCGGGTGGCTGCTCTGGGACTGGGCACCC ACAAGGGCTCAGTGGGCCCAAACCCTTGAAATCCGTGAAACCGGGTGGTCCCAAGAGCTAGAAACTCAGGAAACCCCAGGTGCTCAGGGC CCCGCGTCTCGGGGGCTCCGTGGGGCAGACCCCTGCTAATATATGCAATTCTCCCTCCCCCAGCCCTTCCCTGACCCCTAAGTTATTGCC CGCTCACCTCTCCCAGGCCCCAGGCCGCGGAGCTGGCAGGGTGGCGCCTGCGGTTTCTATGTATTTATAGCAAGTTCTGATGTACATATG >In-frame_ENST00000381759_ENST00000438103_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(amino acids)=1579AA_start in transcript=207_stop in transcript=4946 MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQK KAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFG MWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMI TFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDK LFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYT LALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATG IAVHALSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVV YASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAA LLWAEALNVFQQAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFV SAAEGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGL PSDDRGPLCLLQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSI DHVNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFAS IVAKRLESLGALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCL DVEKDCSITKFLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRG LKWEDAFAKSLALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHC SHSAWNRHCRLAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDAD VKRRQAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLE -------------------------------------------------------------- >In-frame_ENST00000536461_ENST00000361757_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(transcript)=5363nt_BP=958nt CCTCGCCATCCAGAAGTGTGCTTCCCGCACAGCTGCAGCCATGGGGTCTGAGGACCACGGCGCCCAGAACCCCAGCTGTAAAATCATGAC GTTTCGCCCAACCATGGAAGAATTTAAAGACTTCAACAAATACGTGGCCTACATAGAGTCGCAGGGAGCCCACCGGGCGGGCCTGGCCAA GATCATCCCCCCGAAGGAGTGGAAGCCGCGGCAGACGTATGATGACATCGACGACGTGGTGATCCCGGCGCCCATCCAGCAGGTGGTGAC GGGCCAGTCGGGCCTCTTCACGCAGTACAATATCCAGAAGAAGGCCATGACAGTGGGCGAGTACCGCCGCCTGGCCAACAGCGAGAAGTA CTGTACCCCGCGGCACCAGGACTTTGATGACCTTGAACGCAAATACTGGAAGAACCTCACCTTTGTCTCCCCGATCTACGGGGCTGACAT CAGCGGCTCTTTGTATGATGACGACGTGGCCCAGTGGAACATCGGGAGCCTCCGGACCATCCTGGACATGGTGGAGCGCGAGTGCGGCAC CATCATCGAGGGCGTGAACACGCCCTACCTGTACTTCGGCATGTGGAAGACCACCTTCGCCTGGCACACCGAGGACATGGACCTGTACAG CATCAACTACCTGCACTTTGGGGAGCCTAAGTCCTGGTACGCCATCCCACCAGAGCACGGCAAGCGCCTGGAGCGGCTGGCCATCGGCTT CTTCCCCGGGAGCTCGCAGGGCTGCGACGCCTTCCTGCGGCATAAGATGACCCTCATCTCGCCCATCATCCTGAAGAAGTACGGGATCCC CTTCAGCCGGATCACGCAGGAGGCCGGGGAATTCATGATCACATTTCCCTACGGCTACCACGCCGGCTTCAATCACGGGTTCAACTGCGC AGAATCTACCAACTTCGCCACCCTGCGGTGGATTGACTACGGCAAAGTGGCCACTCAGGACTCCTCCTATTTTGAGGACTTCTCCAACAT CTCCATCTTCTCCTCGTCCGTGGACTCCCTGTCGGACATCGTGGACACGCCCGACTTCCTGCCGGCTGACAGCCTCAACCAGGTGTCCAC CATCTGGGACGATAACCCTGCCCCCTCCACCCACGATAAGCTGTTCCAGCTCAGCAGGCCGTTTGCAGGCTTCGAGGACTTTCTGCCCTC CCACAGCACCCCGCTTCTCGTCAGCTACCAGGAGCAGAGTGTGCAGAGCCAGCCAGAGGAGGAGGACGAGGCTGAGGAGGAGGAGGCGGA GGAGCTGGGGCACACAGAGACCTACGCCGACTACGTGCCGTCCAAGTCCAAGATCGGGAAGCAGCACCCAGACCGCGTGGTGGAGACCAG CACACTGTCCAGCGTCCCACCCCCAGACATCACCTACACCCTGGCCCTGCCCTCGGACAGCGGGGCCCTGTCTGCCCTGCAGCTAGAGGC CATCACCTACGCCTGCCAGCAACACGAGGTCCTGCTCCCCAGCGGGCAGCGCGCGGGCTTTCTCATCGGCGATGGGGCCGGCGTGGGCAA AGGCCGGACGGTGGCCGGAGTCATCCTGGAGAACCACCTGCGCGGCCGGAAGAAAGCATTGTGGTTCAGCGTCTCCAACGACCTCAAGTA CGATGCGGAGCGCGACCTGCGGGACATCGAAGCCACGGGCATCGCGGTGCACGCGCTCAGCAAGATCAAGTACGGTGACACCACTACCTC AGAGGGCGTCCTCTTCGCCACCTACTCCGCCCTGATTGGGGAGAGCCAGGCCGGCGGCCAGCACCGCACTCGCCTCCGGCAGATCCTGGA CTGGTGTGGGGAGGCCTTCGAGGGCGTCATCGTGTTCGACGAGTGTCACAAAGCCAAGAATGCCGGCTCCACCAAGATGGGCAAGGCTGT GCTAGACCTGCAGAACAAGCTGCCCCTGGCCCGCGTGGTCTACGCCAGCGCCACAGGTGCCTCTGAGCCTCGGAACATGATCTACATGAG CCGCTTGGGTATCTGGGGCGAGGGCACACCCTTCCGGAACTTTGAGGAGTTCCTGCACGCCATCGAGAAGAGGGGCGTTGGCGCCATGGA GATCGTGGCCATGGACATGAAGGTCAGCGGCATGTACATCGCACGCCAGCTCAGCTTCTCCGGCGTCACCTTCCGCATCGAGGAGATCCC GCTGGCCCCAGCCTTCGAGTGCGTCTACAACCGCGCGGCCCTGCTGTGGGCCGAGGCCCTGAACGTGTTCCAGCAGGCGGCCGACTGGAT CGGCCTGGAGTCGCGCAAGTCCCTGTGGGGCCAGTTCTGGTCGGCACACCAGCGCTTCTTCAAGTATCTGTGCATCGCAGCCAAGGTGCG CCGGCTGGTGGAGCTGGCCCGAGAGGAGCTGGCGCGAGACAAGTGCGTGGTCATCGGGCTGCAGTCCACGGGCGAGGCGCGCACGCGGGA GGTGCTGGGGGAGAACGATGGGCACCTCAACTGCTTCGTCTCGGCCGCTGAAGGCGTGTTCCTGTCGCTAATTCAGAAGCACTTTCCGTC CACCAAGAGAAAGCGGGACAGAGGAGCGGGCAGCAAGCGGAAACGGCGACCTCGGGGACGCGGGGCCAAAGCCCCCCGGCTGGCGTGCGA GACAGCGGGCGTCATCCGCATCAGTGACGACAGCAGCACGGAGTCGGACCCTGGCCTGGACAGCGACTTCAACTCCTCCCCCGAGTCCCT GGTGGATGACGACGTTGTCATCGTTGATGCAGTCGGGCTCCCCAGTGACGACCGGGGACCCCTGTGCCTCCTGCAGAGAGACCCGCATGG CCCCGGGGTCCTGGAGCGGGTGGAGCGGCTGAAGCAGGATCTGCTGGACAAAGTGCGGCGGCTGGGCCGGGAACTGCCAGTCAACACCCT GGACGAGCTCATCGACCAGCTGGGCGGCCCCCAGCGGGTGGCGGAGATGACCGGCAGGAAAGGCCGCGTGGTGTCCAGGCCCGACGGGAC GGTGGCCTTCGAGTCGCGGGCAGAGCAGGGTCTGTCCATCGACCACGTGAACCTCAGGGAGAAGCAGCGCTTCATGAGCGGCGAGAAGCT CGTGGCCATCATCTCGGAGGCCTCCAGCTCGGGTGTCTCCCTCCAAGCCGACCGCCGTGTCCAGAACCAGCGGCGCCGCGTGCACATGAC CTTGGAGCTGCCGTGGAGCGCCGACCGCGCCATCCAGCAGTTCGGCCGCACCCACCGGTCCAACCAGGTCTCCGCGCCAGAGTATGTCTT CCTCATCTCGGAGCTGGCCGGGGAGCGCCGGTTCGCCTCCATCGTGGCCAAGCGCCTGGAGAGTCTGGGGGCCCTGACCCACGGAGACCG CCGCGCCACGGAGTCCCGTGACCTCAGCAAGTACAACTTTGAGAACAAGTATGGCACCCGGGCCCTGCACTGTGTCCTCACCACCATCCT GAGCCAGACTGAGAACAAAGTGCCTGTGCCCCAGGGATACCCTGGAGGGGTCCCCACCTTCTTCCGGGACATGAAGCAGGGCCTGCTGTC TGTGGGCATTGGTGGCCGGGAGTCCCGGAATGGCTGCCTGGACGTGGAGAAGGACTGTTCCATCACCAAGTTCCTGAACCGCATCCTGGG GCTGGAGGTGCACAAGCAGAACGCCCTGTTCCAGTACTTCTCAGACACCTTCGACCACCTCATCGAGATGGACAAGCGGGAGGGCAAATA CGACATGGGCATCCTGGACCTTGCTCCCGGTATCGAGGAGATCTACGAGGAGAGCCAGCAGGTGTTCCTGGCTCCCGGGCACCCGCAGGA CGGGCAGGTGGTCTTCTACAAGATCAGCGTGGACCGCGGCCTGAAGTGGGAGGACGCCTTTGCCAAGTCGCTGGCGCTGACGGGCCCCTA TGACGGCTTCTACCTCTCCTACAAGGTCCGCGGTAACAAGCCCAGCTGCCTGCTGGCGGAGCAGAACCGCGGCCAGTTCTTCACGGTGTA CAAGCCCAACATCGGCCGGCAGAGCCAGCTGGAGGCCCTGGACAGCCTCCGCCGCAAGTTCCACCGGGTCACCGCGGAGGAGGCCAAGGA GCCCTGGGAGAGTGGCTACGCTTTGTCGCTGACGCACTGCAGCCACAGCGCCTGGAACCGGCACTGCCGGCTGGCGCAGGAGGGTAAGGA CTGCCTGCAGGGGCTGCGGCTGCGGCACCACTACATGCTGTGCGGCGCGCTGCTGCGCGTGTGGGGCCGCATCGCCGCCGTCATGGCCGA CGTCAGCAGCAGCAGCTACCTGCAGATCGTGCGGCTGAAGACCAAGGACAGGAAGAAGCAAGTGGGCATCAAGATCCCCGAGGGCTGCGT GCGCCGGGTGCTGCAGGAGCTGCGGCTGATGGATGCGGACGTGAAGCGCAGGCAGGCGCCCGCCCTGGGCTGCCCCGCCCCGCCCGCCCC GCGCCCGCTGGCGCTGCCTTGCGGCCCCGGAGAGGTGCTGGACCTCACCTACAGCCCCCCGGCCGAGGCCTTCCCGCCGCCCCCGCACTT CTCTTTCCCGGCGCCGCTGTCCCTGGACGCCGGCCCCGGCGTCGTGCCGCTGGGCACCCCCGACGCCCAGGCCGACCCTGCGGCCCTCGC GCACCAGGGCTGCGACATCAACTTCAAGGAGGTGCTGGAGGACATGCTGCGCTCGCTGCACGCGGGGCCGCCCTCCGAGGGCGCGCTGGG GGAGGGCGCGGGGGCGGGGGGCGCGGCGGGCGGTGGTCCCGAGCGGCAGAGCGTGATCCAGTTCAGCCCACCCTTCCCCGGCGCCCAGGC TCCTCTCTGACACGCCTTTAGGCGAAACATGCCCCAAGACACAGGGACCGTTTCTCCCCTAGGAGCAGCGGTGGGGAGCAGGGCCAAGGT CCCCTGACCACTGCTCAGAGGAGCCCTAGGCCCTGGCCGCAGTGCCTTCAGCGCCCGACCCGGGCCCCCACCTGGTCAGCCCTGGCGGGG CCCACTCAGGACAGCTGGGGGCCGGGGCGTGGCAGGGCCCTCTCTGTGCCTCTCCTCCCAAGTAGGAAGGGGCTCCGGGTGGCTGCTCTG GGACTGGGCACCCACAAGGGCTCAGTGGGCCCAAACCCTTGAAATCCGTGAAACCGGGTGGTCCCAAGAGCTAGAAACTCAGGAAACCCC AGGTGCTCAGGGCCCCGCGTCTCGGGGGCTCCGTGGGGCAGACCCCTGCTAATATATGCAATTCTCCCTCCCCCAGCCCTTCCCTGACCC CTAAGTTATTGCCCGCTCACCTCTCCCAGGCCCCAGGCCGCGGAGCTGGCAGGGTGGCGCCTGCGGTTTCTATGTATTTATAGCAAGTTC >In-frame_ENST00000536461_ENST00000361757_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(amino acids)=1579AA_start in transcript=40_stop in transcript=4779 MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQK KAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFG MWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMI TFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDK LFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYT LALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATG IAVHALSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVV YASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAA LLWAEALNVFQQAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFV SAAEGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGL PSDDRGPLCLLQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSI DHVNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFAS IVAKRLESLGALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCL DVEKDCSITKFLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRG LKWEDAFAKSLALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHC SHSAWNRHCRLAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDAD VKRRQAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLE -------------------------------------------------------------- >In-frame_ENST00000536461_ENST00000587024_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(transcript)=5329nt_BP=958nt CCTCGCCATCCAGAAGTGTGCTTCCCGCACAGCTGCAGCCATGGGGTCTGAGGACCACGGCGCCCAGAACCCCAGCTGTAAAATCATGAC GTTTCGCCCAACCATGGAAGAATTTAAAGACTTCAACAAATACGTGGCCTACATAGAGTCGCAGGGAGCCCACCGGGCGGGCCTGGCCAA GATCATCCCCCCGAAGGAGTGGAAGCCGCGGCAGACGTATGATGACATCGACGACGTGGTGATCCCGGCGCCCATCCAGCAGGTGGTGAC GGGCCAGTCGGGCCTCTTCACGCAGTACAATATCCAGAAGAAGGCCATGACAGTGGGCGAGTACCGCCGCCTGGCCAACAGCGAGAAGTA CTGTACCCCGCGGCACCAGGACTTTGATGACCTTGAACGCAAATACTGGAAGAACCTCACCTTTGTCTCCCCGATCTACGGGGCTGACAT CAGCGGCTCTTTGTATGATGACGACGTGGCCCAGTGGAACATCGGGAGCCTCCGGACCATCCTGGACATGGTGGAGCGCGAGTGCGGCAC CATCATCGAGGGCGTGAACACGCCCTACCTGTACTTCGGCATGTGGAAGACCACCTTCGCCTGGCACACCGAGGACATGGACCTGTACAG CATCAACTACCTGCACTTTGGGGAGCCTAAGTCCTGGTACGCCATCCCACCAGAGCACGGCAAGCGCCTGGAGCGGCTGGCCATCGGCTT CTTCCCCGGGAGCTCGCAGGGCTGCGACGCCTTCCTGCGGCATAAGATGACCCTCATCTCGCCCATCATCCTGAAGAAGTACGGGATCCC CTTCAGCCGGATCACGCAGGAGGCCGGGGAATTCATGATCACATTTCCCTACGGCTACCACGCCGGCTTCAATCACGGGTTCAACTGCGC AGAATCTACCAACTTCGCCACCCTGCGGTGGATTGACTACGGCAAAGTGGCCACTCAGGACTCCTCCTATTTTGAGGACTTCTCCAACAT CTCCATCTTCTCCTCGTCCGTGGACTCCCTGTCGGACATCGTGGACACGCCCGACTTCCTGCCGGCTGACAGCCTCAACCAGGTGTCCAC CATCTGGGACGATAACCCTGCCCCCTCCACCCACGATAAGCTGTTCCAGCTCAGCAGGCCGTTTGCAGGCTTCGAGGACTTTCTGCCCTC CCACAGCACCCCGCTTCTCGTCAGCTACCAGGAGCAGAGTGTGCAGAGCCAGCCAGAGGAGGAGGACGAGGCTGAGGAGGAGGAGGCGGA GGAGCTGGGGCACACAGAGACCTACGCCGACTACGTGCCGTCCAAGTCCAAGATCGGGAAGCAGCACCCAGACCGCGTGGTGGAGACCAG CACACTGTCCAGCGTCCCACCCCCAGACATCACCTACACCCTGGCCCTGCCCTCGGACAGCGGGGCCCTGTCTGCCCTGCAGCTAGAGGC CATCACCTACGCCTGCCAGCAACACGAGGTCCTGCTCCCCAGCGGGCAGCGCGCGGGCTTTCTCATCGGCGATGGGGCCGGCGTGGGCAA AGGCCGGACGGTGGCCGGAGTCATCCTGGAGAACCACCTGCGCGGCCGGAAGAAAGCATTGTGGTTCAGCGTCTCCAACGACCTCAAGTA CGATGCGGAGCGCGACCTGCGGGACATCGAAGCCACGGGCATCGCGGTGCACGCGCTCAGCAAGATCAAGTACGGTGACACCACTACCTC AGAGGGCGTCCTCTTCGCCACCTACTCCGCCCTGATTGGGGAGAGCCAGGCCGGCGGCCAGCACCGCACTCGCCTCCGGCAGATCCTGGA CTGGTGTGGGGAGGCCTTCGAGGGCGTCATCGTGTTCGACGAGTGTCACAAAGCCAAGAATGCCGGCTCCACCAAGATGGGCAAGGCTGT GCTAGACCTGCAGAACAAGCTGCCCCTGGCCCGCGTGGTCTACGCCAGCGCCACAGGTGCCTCTGAGCCTCGGAACATGATCTACATGAG CCGCTTGGGTATCTGGGGCGAGGGCACACCCTTCCGGAACTTTGAGGAGTTCCTGCACGCCATCGAGAAGAGGGGCGTTGGCGCCATGGA GATCGTGGCCATGGACATGAAGGTCAGCGGCATGTACATCGCACGCCAGCTCAGCTTCTCCGGCGTCACCTTCCGCATCGAGGAGATCCC GCTGGCCCCAGCCTTCGAGTGCGTCTACAACCGCGCGGCCCTGCTGGCGGCCGACTGGATCGGCCTGGAGTCGCGCAAGTCCCTGTGGGG CCAGTTCTGGTCGGCACACCAGCGCTTCTTCAAGTATCTGTGCATCGCAGCCAAGGTGCGCCGGCTGGTGGAGCTGGCCCGAGAGGAGCT GGCGCGAGACAAGTGCGTGGTCATCGGGCTGCAGTCCACGGGCGAGGCGCGCACGCGGGAGGTGCTGGGGGAGAACGATGGGCACCTCAA CTGCTTCGTCTCGGCCGCTGAAGGCGTGTTCCTGTCGCTAATTCAGAAGCACTTTCCGTCCACCAAGAGAAAGCGGGACAGAGGAGCGGG CAGCAAGCGGAAACGGCGACCTCGGGGACGCGGGGCCAAAGCCCCCCGGCTGGCGTGCGAGACAGCGGGCGTCATCCGCATCAGTGACGA CAGCAGCACGGAGTCGGACCCTGGCCTGGACAGCGACTTCAACTCCTCCCCCGAGTCCCTGGTGGATGACGACGTTGTCATCGTTGATGC AGTCGGGCTCCCCAGTGACGACCGGGGACCCCTGTGCCTCCTGCAGAGAGACCCGCATGGCCCCGGGGTCCTGGAGCGGGTGGAGCGGCT GAAGCAGGATCTGCTGGACAAAGTGCGGCGGCTGGGCCGGGAACTGCCAGTCAACACCCTGGACGAGCTCATCGACCAGCTGGGCGGCCC CCAGCGGGTGGCGGAGATGACCGGCAGGAAAGGCCGCGTGGTGTCCAGGCCCGACGGGACGGTGGCCTTCGAGTCGCGGGCAGAGCAGGG TCTGTCCATCGACCACGTGAACCTCAGGGAGAAGCAGCGCTTCATGAGCGGCGAGAAGCTCGTGGCCATCATCTCGGAGGCCTCCAGCTC GGGTGTCTCCCTCCAAGCCGACCGCCGTGTCCAGAACCAGCGGCGCCGCGTGCACATGACCTTGGAGCTGCCGTGGAGCGCCGACCGCGC CATCCAGCAGTTCGGCCGCACCCACCGGTCCAACCAGGTCTCCGCGCCAGAGTATGTCTTCCTCATCTCGGAGCTGGCCGGGGAGCGCCG GTTCGCCTCCATCGTGGCCAAGCGCCTGGAGAGTCTGGGGGCCCTGACCCACGGAGACCGCCGCGCCACGGAGTCCCGTGACCTCAGCAA GTACAACTTTGAGAACAAGTATGGCACCCGGGCCCTGCACTGTGTCCTCACCACCATCCTGAGCCAGACTGAGAACAAAGTGCCTGTGCC CCAGGGATACCCTGGAGGGGTCCCCACCTTCTTCCGGGACATGAAGCAGGGCCTGCTGTCTGTGGGCATTGGTGGCCGGGAGTCCCGGAA TGGCTGCCTGGACGTGGAGAAGGACTGTTCCATCACCAAGTTCCTGAACCGCATCCTGGGGCTGGAGGTGCACAAGCAGAACGCCCTGTT CCAGTACTTCTCAGACACCTTCGACCACCTCATCGAGATGGACAAGCGGGAGGGCAAATACGACATGGGCATCCTGGACCTTGCTCCCGG TATCGAGGAGATCTACGAGGAGAGCCAGCAGGTGTTCCTGGCTCCCGGGCACCCGCAGGACGGGCAGGTGGTCTTCTACAAGATCAGCGT GGACCGCGGCCTGAAGTGGGAGGACGCCTTTGCCAAGTCGCTGGCGCTGACGGGCCCCTATGACGGCTTCTACCTCTCCTACAAGGTCCG CGGTAACAAGCCCAGCTGCCTGCTGGCGGAGCAGAACCGCGGCCAGTTCTTCACGGTGTACAAGCCCAACATCGGCCGGCAGAGCCAGCT GGAGGCCCTGGACAGCCTCCGCCGCAAGTTCCACCGGGTCACCGCGGAGGAGGCCAAGGAGCCCTGGGAGAGTGGCTACGCTTTGTCGCT GACGCACTGCAGCCACAGCGCCTGGAACCGGCACTGCCGGCTGGCGCAGGAGGGTAAGGACTGCCTGCAGGGGCTGCGGCTGCGGCACCA CTACATGCTGTGCGGCGCGCTGCTGCGCGTGTGGGGCCGCATCGCCGCCGTCATGGCCGACGTCAGCAGCAGCAGCTACCTGCAGATCGT GCGGCTGAAGACCAAGGACAGGAAGAAGCAAGTGGGCATCAAGATCCCCGAGGGCTGCGTGCGCCGGGTGCTGCAGGAGCTGCGGCTGAT GGATGCGGACGTGAAGCGCAGGCAGGCGCCCGCCCTGGGCTGCCCCGCCCCGCCCGCCCCGCGCCCGCTGGCGCTGCCTTGCGGCCCCGG AGAGGTGCTGGACCTCACCTACAGCCCCCCGGCCGAGGCCTTCCCGCCGCCCCCGCACTTCTCTTTCCCGGCGCCGCTGTCCCTGGACGC CGGCCCCGGCGTCGTGCCGCTGGGCACCCCCGACGCCCAGGCCGACCCTGCGGCCCTCGCGCACCAGGGCTGCGACATCAACTTCAAGGA GGTGCTGGAGGACATGCTGCGCTCGCTGCACGCGGGGCCGCCCTCCGAGGGCGCGCTGGGGGAGGGCGCGGGGGCGGGGGGCGCGGCGGG CGGTGGTCCCGAGCGGCAGAGCGTGATCCAGTTCAGCCCACCCTTCCCCGGCGCCCAGGCTCCTCTCTGACACGCCTTTAGGCGAAACAT GCCCCAAGACACAGGGACCGTTTCTCCCCTAGGAGCAGCGGTGGGGAGCAGGGCCAAGGTCCCCTGACCACTGCTCAGAGGAGCCCTAGG CCCTGGCCGCAGTGCCTTCAGCGCCCGACCCGGGCCCCCACCTGGTCAGCCCTGGCGGGGCCCACTCAGGACAGCTGGGGGCCGGGGCGT GGCAGGGCCCTCTCTGTGCCTCTCCTCCCAAGTAGGAAGGGGCTCCGGGTGGCTGCTCTGGGACTGGGCACCCACAAGGGCTCAGTGGGC CCAAACCCTTGAAATCCGTGAAACCGGGTGGTCCCAAGAGCTAGAAACTCAGGAAACCCCAGGTGCTCAGGGCCCCGCGTCTCGGGGGCT CCGTGGGGCAGACCCCTGCTAATATATGCAATTCTCCCTCCCCCAGCCCTTCCCTGACCCCTAAGTTATTGCCCGCTCACCTCTCCCAGG CCCCAGGCCGCGGAGCTGGCAGGGTGGCGCCTGCGGTTTCTATGTATTTATAGCAAGTTCTGATGTACATATGTAAAGGACTTTTTTAAA >In-frame_ENST00000536461_ENST00000587024_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(amino acids)=1569AA_start in transcript=40_stop in transcript=4749 MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQK KAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFG MWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMI TFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDK LFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYT LALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATG IAVHALSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVV YASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAA LLAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFVSAAEGVFLSL IQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGLPSDDRGPLCL LQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSIDHVNLREKQR FMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFASIVAKRLESLG ALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCLDVEKDCSITK FLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRGLKWEDAFAKS LALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHCSHSAWNRHCR LAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDADVKRRQAPALG CPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGP -------------------------------------------------------------- >In-frame_ENST00000536461_ENST00000438103_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(transcript)=5358nt_BP=958nt CCTCGCCATCCAGAAGTGTGCTTCCCGCACAGCTGCAGCCATGGGGTCTGAGGACCACGGCGCCCAGAACCCCAGCTGTAAAATCATGAC GTTTCGCCCAACCATGGAAGAATTTAAAGACTTCAACAAATACGTGGCCTACATAGAGTCGCAGGGAGCCCACCGGGCGGGCCTGGCCAA GATCATCCCCCCGAAGGAGTGGAAGCCGCGGCAGACGTATGATGACATCGACGACGTGGTGATCCCGGCGCCCATCCAGCAGGTGGTGAC GGGCCAGTCGGGCCTCTTCACGCAGTACAATATCCAGAAGAAGGCCATGACAGTGGGCGAGTACCGCCGCCTGGCCAACAGCGAGAAGTA CTGTACCCCGCGGCACCAGGACTTTGATGACCTTGAACGCAAATACTGGAAGAACCTCACCTTTGTCTCCCCGATCTACGGGGCTGACAT CAGCGGCTCTTTGTATGATGACGACGTGGCCCAGTGGAACATCGGGAGCCTCCGGACCATCCTGGACATGGTGGAGCGCGAGTGCGGCAC CATCATCGAGGGCGTGAACACGCCCTACCTGTACTTCGGCATGTGGAAGACCACCTTCGCCTGGCACACCGAGGACATGGACCTGTACAG CATCAACTACCTGCACTTTGGGGAGCCTAAGTCCTGGTACGCCATCCCACCAGAGCACGGCAAGCGCCTGGAGCGGCTGGCCATCGGCTT CTTCCCCGGGAGCTCGCAGGGCTGCGACGCCTTCCTGCGGCATAAGATGACCCTCATCTCGCCCATCATCCTGAAGAAGTACGGGATCCC CTTCAGCCGGATCACGCAGGAGGCCGGGGAATTCATGATCACATTTCCCTACGGCTACCACGCCGGCTTCAATCACGGGTTCAACTGCGC AGAATCTACCAACTTCGCCACCCTGCGGTGGATTGACTACGGCAAAGTGGCCACTCAGGACTCCTCCTATTTTGAGGACTTCTCCAACAT CTCCATCTTCTCCTCGTCCGTGGACTCCCTGTCGGACATCGTGGACACGCCCGACTTCCTGCCGGCTGACAGCCTCAACCAGGTGTCCAC CATCTGGGACGATAACCCTGCCCCCTCCACCCACGATAAGCTGTTCCAGCTCAGCAGGCCGTTTGCAGGCTTCGAGGACTTTCTGCCCTC CCACAGCACCCCGCTTCTCGTCAGCTACCAGGAGCAGAGTGTGCAGAGCCAGCCAGAGGAGGAGGACGAGGCTGAGGAGGAGGAGGCGGA GGAGCTGGGGCACACAGAGACCTACGCCGACTACGTGCCGTCCAAGTCCAAGATCGGGAAGCAGCACCCAGACCGCGTGGTGGAGACCAG CACACTGTCCAGCGTCCCACCCCCAGACATCACCTACACCCTGGCCCTGCCCTCGGACAGCGGGGCCCTGTCTGCCCTGCAGCTAGAGGC CATCACCTACGCCTGCCAGCAACACGAGGTCCTGCTCCCCAGCGGGCAGCGCGCGGGCTTTCTCATCGGCGATGGGGCCGGCGTGGGCAA AGGCCGGACGGTGGCCGGAGTCATCCTGGAGAACCACCTGCGCGGCCGGAAGAAAGCATTGTGGTTCAGCGTCTCCAACGACCTCAAGTA CGATGCGGAGCGCGACCTGCGGGACATCGAAGCCACGGGCATCGCGGTGCACGCGCTCAGCAAGATCAAGTACGGTGACACCACTACCTC AGAGGGCGTCCTCTTCGCCACCTACTCCGCCCTGATTGGGGAGAGCCAGGCCGGCGGCCAGCACCGCACTCGCCTCCGGCAGATCCTGGA CTGGTGTGGGGAGGCCTTCGAGGGCGTCATCGTGTTCGACGAGTGTCACAAAGCCAAGAATGCCGGCTCCACCAAGATGGGCAAGGCTGT GCTAGACCTGCAGAACAAGCTGCCCCTGGCCCGCGTGGTCTACGCCAGCGCCACAGGTGCCTCTGAGCCTCGGAACATGATCTACATGAG CCGCTTGGGTATCTGGGGCGAGGGCACACCCTTCCGGAACTTTGAGGAGTTCCTGCACGCCATCGAGAAGAGGGGCGTTGGCGCCATGGA GATCGTGGCCATGGACATGAAGGTCAGCGGCATGTACATCGCACGCCAGCTCAGCTTCTCCGGCGTCACCTTCCGCATCGAGGAGATCCC GCTGGCCCCAGCCTTCGAGTGCGTCTACAACCGCGCGGCCCTGCTGTGGGCCGAGGCCCTGAACGTGTTCCAGCAGGCGGCCGACTGGAT CGGCCTGGAGTCGCGCAAGTCCCTGTGGGGCCAGTTCTGGTCGGCACACCAGCGCTTCTTCAAGTATCTGTGCATCGCAGCCAAGGTGCG CCGGCTGGTGGAGCTGGCCCGAGAGGAGCTGGCGCGAGACAAGTGCGTGGTCATCGGGCTGCAGTCCACGGGCGAGGCGCGCACGCGGGA GGTGCTGGGGGAGAACGATGGGCACCTCAACTGCTTCGTCTCGGCCGCTGAAGGCGTGTTCCTGTCGCTAATTCAGAAGCACTTTCCGTC CACCAAGAGAAAGCGGGACAGAGGAGCGGGCAGCAAGCGGAAACGGCGACCTCGGGGACGCGGGGCCAAAGCCCCCCGGCTGGCGTGCGA GACAGCGGGCGTCATCCGCATCAGTGACGACAGCAGCACGGAGTCGGACCCTGGCCTGGACAGCGACTTCAACTCCTCCCCCGAGTCCCT GGTGGATGACGACGTTGTCATCGTTGATGCAGTCGGGCTCCCCAGTGACGACCGGGGACCCCTGTGCCTCCTGCAGAGAGACCCGCATGG CCCCGGGGTCCTGGAGCGGGTGGAGCGGCTGAAGCAGGATCTGCTGGACAAAGTGCGGCGGCTGGGCCGGGAACTGCCAGTCAACACCCT GGACGAGCTCATCGACCAGCTGGGCGGCCCCCAGCGGGTGGCGGAGATGACCGGCAGGAAAGGCCGCGTGGTGTCCAGGCCCGACGGGAC GGTGGCCTTCGAGTCGCGGGCAGAGCAGGGTCTGTCCATCGACCACGTGAACCTCAGGGAGAAGCAGCGCTTCATGAGCGGCGAGAAGCT CGTGGCCATCATCTCGGAGGCCTCCAGCTCGGGTGTCTCCCTCCAAGCCGACCGCCGTGTCCAGAACCAGCGGCGCCGCGTGCACATGAC CTTGGAGCTGCCGTGGAGCGCCGACCGCGCCATCCAGCAGTTCGGCCGCACCCACCGGTCCAACCAGGTCTCCGCGCCAGAGTATGTCTT CCTCATCTCGGAGCTGGCCGGGGAGCGCCGGTTCGCCTCCATCGTGGCCAAGCGCCTGGAGAGTCTGGGGGCCCTGACCCACGGAGACCG CCGCGCCACGGAGTCCCGTGACCTCAGCAAGTACAACTTTGAGAACAAGTATGGCACCCGGGCCCTGCACTGTGTCCTCACCACCATCCT GAGCCAGACTGAGAACAAAGTGCCTGTGCCCCAGGGATACCCTGGAGGGGTCCCCACCTTCTTCCGGGACATGAAGCAGGGCCTGCTGTC TGTGGGCATTGGTGGCCGGGAGTCCCGGAATGGCTGCCTGGACGTGGAGAAGGACTGTTCCATCACCAAGTTCCTGAACCGCATCCTGGG GCTGGAGGTGCACAAGCAGAACGCCCTGTTCCAGTACTTCTCAGACACCTTCGACCACCTCATCGAGATGGACAAGCGGGAGGGCAAATA CGACATGGGCATCCTGGACCTTGCTCCCGGTATCGAGGAGATCTACGAGGAGAGCCAGCAGGTGTTCCTGGCTCCCGGGCACCCGCAGGA CGGGCAGGTGGTCTTCTACAAGATCAGCGTGGACCGCGGCCTGAAGTGGGAGGACGCCTTTGCCAAGTCGCTGGCGCTGACGGGCCCCTA TGACGGCTTCTACCTCTCCTACAAGGTCCGCGGTAACAAGCCCAGCTGCCTGCTGGCGGAGCAGAACCGCGGCCAGTTCTTCACGGTGTA CAAGCCCAACATCGGCCGGCAGAGCCAGCTGGAGGCCCTGGACAGCCTCCGCCGCAAGTTCCACCGGGTCACCGCGGAGGAGGCCAAGGA GCCCTGGGAGAGTGGCTACGCTTTGTCGCTGACGCACTGCAGCCACAGCGCCTGGAACCGGCACTGCCGGCTGGCGCAGGAGGGTAAGGA CTGCCTGCAGGGGCTGCGGCTGCGGCACCACTACATGCTGTGCGGCGCGCTGCTGCGCGTGTGGGGCCGCATCGCCGCCGTCATGGCCGA CGTCAGCAGCAGCAGCTACCTGCAGATCGTGCGGCTGAAGACCAAGGACAGGAAGAAGCAAGTGGGCATCAAGATCCCCGAGGGCTGCGT GCGCCGGGTGCTGCAGGAGCTGCGGCTGATGGATGCGGACGTGAAGCGCAGGCAGGCGCCCGCCCTGGGCTGCCCCGCCCCGCCCGCCCC GCGCCCGCTGGCGCTGCCTTGCGGCCCCGGAGAGGTGCTGGACCTCACCTACAGCCCCCCGGCCGAGGCCTTCCCGCCGCCCCCGCACTT CTCTTTCCCGGCGCCGCTGTCCCTGGACGCCGGCCCCGGCGTCGTGCCGCTGGGCACCCCCGACGCCCAGGCCGACCCTGCGGCCCTCGC GCACCAGGGCTGCGACATCAACTTCAAGGAGGTGCTGGAGGACATGCTGCGCTCGCTGCACGCGGGGCCGCCCTCCGAGGGCGCGCTGGG GGAGGGCGCGGGGGCGGGGGGCGCGGCGGGCGGTGGTCCCGAGCGGCAGAGCGTGATCCAGTTCAGCCCACCCTTCCCCGGCGCCCAGGC TCCTCTCTGACACGCCTTTAGGCGAAACATGCCCCAAGACACAGGGACCGTTTCTCCCCTAGGAGCAGCGGTGGGGAGCAGGGCCAAGGT CCCCTGACCACTGCTCAGAGGAGCCCTAGGCCCTGGCCGCAGTGCCTTCAGCGCCCGACCCGGGCCCCCACCTGGTCAGCCCTGGCGGGG CCCACTCAGGACAGCTGGGGGCCGGGGCGTGGCAGGGCCCTCTCTGTGCCTCTCCTCCCAAGTAGGAAGGGGCTCCGGGTGGCTGCTCTG GGACTGGGCACCCACAAGGGCTCAGTGGGCCCAAACCCTTGAAATCCGTGAAACCGGGTGGTCCCAAGAGCTAGAAACTCAGGAAACCCC AGGTGCTCAGGGCCCCGCGTCTCGGGGGCTCCGTGGGGCAGACCCCTGCTAATATATGCAATTCTCCCTCCCCCAGCCCTTCCCTGACCC CTAAGTTATTGCCCGCTCACCTCTCCCAGGCCCCAGGCCGCGGAGCTGGCAGGGTGGCGCCTGCGGTTTCTATGTATTTATAGCAAGTTC >In-frame_ENST00000536461_ENST00000438103_TCGA-WY-A85E-01A_KDM4B_chr19_5082515_-_SBNO2_chr19_1127764_length(amino acids)=1579AA_start in transcript=40_stop in transcript=4779 MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQK KAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFG MWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMI TFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDK LFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYT LALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATG IAVHALSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVV YASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAA LLWAEALNVFQQAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFV SAAEGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGL PSDDRGPLCLLQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSI DHVNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFAS IVAKRLESLGALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCL DVEKDCSITKFLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRG LKWEDAFAKSLALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHC SHSAWNRHCRLAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDAD VKRRQAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLE -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for KDM4B-SBNO2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for KDM4B-SBNO2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for KDM4B-SBNO2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | KDM4B | C0025149 | Medulloblastoma | 1 | CTD_human |
| Hgene | KDM4B | C0025202 | melanoma | 1 | CTD_human |
| Hgene | KDM4B | C0205833 | Medullomyoblastoma | 1 | CTD_human |
| Hgene | KDM4B | C0278510 | Childhood Medulloblastoma | 1 | CTD_human |
| Hgene | KDM4B | C0278876 | Adult Medulloblastoma | 1 | CTD_human |
| Hgene | KDM4B | C0751291 | Desmoplastic Medulloblastoma | 1 | CTD_human |
| Hgene | KDM4B | C1275668 | Melanotic medulloblastoma | 1 | CTD_human |
| Tgene | SBNO2 | C0036341 | Schizophrenia | 1 | PSYGENET |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies